KEN YAMAGUCHI

Last Updated :2026/06/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Professor
E-mail
soulkenhiroshima-u.ac.jp
Self-introduction
The discipline of obstetrics and gynecology encompasses four major subspecialties: gynecologic oncology, perinatology, reproductive medicine, and women's healthcare/ My primary focus lies in gynecologic oncology, within which I actively advance the implementation of robotic surgery, digital health technologies, and patient-centered care. In addition, I place strong emphasis on education initiatives designed to ensure that trainees and colleagues are empowered to excel within their respective areas of specialization.

Basic Information

Major Professional Backgrounds

  • 1999/05, 1999/08, Kyoto University, Clinical Resident
  • 1999/09, 1999/11, Clinical Resident
  • 1999/12, 2000/09, Kyoto University, Clinical Resident
  • 2000/10, 2003/03, Japanese Red Cross Otsu Hospital, Doctor
  • 2003/04, 2004/03, Nagahama City Hospital, Doctor
  • 2004/04, 2005/03, Kyoto University, Clinical Fellow
  • 2009/02, 2011/03, Duke University Medical Center
  • 2011/04, 2011/09, Kyoto University
  • 2011/10, 2013/05, Japan Baptist hospital, Doctor
  • 2013/06, 2013/11, Kyoto University
  • 2013/11, 2017/03, Kyoto University, Assistant Professor
  • 2017/04, National Hospital Organization Kyoto Medical Center
  • 2019/03, 2025/03, Kyoto University, Lecturer
  • 2025/06/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Professor

Educational Backgrounds

  • Kyoto University, Japan, 2005/04, 2009/03
  • Osaka City University, School of Medicine, Japan, 1993/04, 1999/03

Academic Degrees

  • Kyoto University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Biological Sciences;Oncology;Tumor biology
  • Biological Sciences;Oncology;Tumor diagnostics
  • Biological Sciences;Oncology;Tumor therapeutics
  • Medicine,dentistry, and pharmacy;Clinical surgery;Obstetrics and gynecology

Affiliated Academic Societies

  • Japan Society of Clinical Genetics in Obstetrics and Gynecology, 2026/02
  • Japanese Society of Female Pelvic Floor Medicine, 2025/11
  • Asian Society for Gynecologic Robotic Surgery, 2025/04
  • Japan Society of Gynecological and Obstetrical Surgery, 2025/04
  • Japan Society for Endoscopic Surgery, 2023/03
  • Japan Society for Menopause and Women's Health, 2020/09
  • Japanese Society of Genetic Counseling, 2019/06
  • Japan Sarcoma Association, 2018/10
  • Japan Society of Human Genetics, 2017/08
  • Japanese Society for Clinical Molecular Morphology, 2017/04
  • Japan Society of Endometriosis, 2017/01
  • Japanese Cancer Association, 2007/09
  • Japan Society of Perinatal and Neonatal Medicine, 2011/11
  • Japan Society of Gynecologic Oncology, 2007/12
  • Japan Society of Clinical Oncology, 2006/04
  • Japan Society of Obstetrics and Gynecology, 1999/04

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, Year, Systemic Disease Control
  2. 2026, Undergraduate Education, Intensive, Practice for medical research
  3. 2026, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2026, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  5. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Obstetrics and Gynecology
  6. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Obstetrics and Gynecology
  7. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Obstetrics and Gynecology
  8. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Obstetrics and Gynecology
  9. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Gynecologic Cancer Treatment
  10. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Gynecologic Cancer Treatment

Research Activities

Academic Papers

  1. Electronic patient-reported outcomes as digital therapeutics for patients with cancer: a narrative review of current practices and future directions., Int J Clin Oncol., 20241216
  2. Feasibility/clinical utility of half-Fourier single-shot turbo spin echo imaging combined with deep learning reconstruction in gynecologic magnetic resonance imaging., Abdom Radiol (NY)., 20241218
  3. Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study., JMIR Cancer., 11, e58093, 20250120
  4. Prognostic significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in uterine carcinosarcoma., Int J Clin Oncol., 202501008
  5. Re-evaluating prognostic factors for cervical cancer with lymph node metastasis: a Japanese multicenter cohort study based on FIGO 2018., Int J Clin Oncol., 20250116
  6. Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer., Cancer Immunol Immunother., 74(3), 84, 20250201
  7. Awareness and attitude toward cardio-oncology among Japanese gynecologic oncologists in managing patients with endometrial cancer: The Japanese Gynecologic Oncology Group (JGOG) questionnaire surveys., J Obstet Gynaecol Res., 20250205
  8. A Rare Case of Ovarian Serous Borderline Tumor Recurrence with Muscle Metastasis., Am J Case Rep., 26, e946680, 20250403
  9. Online Live Streaming System for Robotic Surgery With Bidirectional Discussion Through a Commentator: A Multi-Institutional Observational Study., Asian J Endosc Surg., 18(1), e70072, 20250427
  10. Usefulness of video explanation for informed consent in gynecologic surgery., Int J Gynaecol Obstet., 20250612
  11. A Case of Intramural Adenosarcoma With Sarcomatous Overgrowth Associated With Adenomyosis and Endometriosis., Cureus., 17(7), e88422, 20250721
  12. Defecation disorder after anterior pelvic exenteration., J Obstet Gynaecol Res., 51(7), e16353, 20250727
  13. Origin of Endometrioid Carcinoma Adjacent to Extraovarian Endometriosis: Detailed Molecular Analyses., Int J Gynecol Pathol., 20250729
  14. Therapeutic impact of neoadjuvant chemotherapy on lymph node metastasis in locally advanced cervical cancer., J Obstet Gynaecol Res., 52(8), e70022, 20250828
  15. High-grade gliomas derived from an ovarian mature teratoma: clonal dynamics and genetic insights., Int Cancer Conf J., 14(4), 421-427, 20250908
  16. Real-world application of large language models for automated TNM staging using unstructured gynecologic oncology reports., NPJ Precis Oncol., 9(1), 366, 20251119
  17. Possible overestimation of treatment effects of pelvic and para-aortic lymphadenectomy for early-stage ovarian clear cell carcinoma: a retrospective propensity-score weighted multi-center cohort study., J Gynecol Oncol., 37(2), e24, 20251224
  18. Oligoclonal B cell expansion and passenger fusion genes predict response to Nivolumab in recurrent ovarian cancer: phase II Kyoto trial., Cancer Immunol Immunother., 75(2), 52, 20260127
  19. Healthcare provider bias in cancer treatment decisions for elderly patients., Taiwan J Obstet Gynecol., 65(1), 29-33, 20260128
  20. Digital spatial profiling reveals additive effects of triple therapy on tumor microenvironment: anti-PD-L1, anti-VEGF, and PARP inhibition in mouse models., Cancer Immunol Immunother., 75(3), 70, 20260207
  21. Adjuvant Chemotherapy in Stage I Ovarian Clear Cell Carcinoma: A Systematic Review and Meta-analysis., Obstet Gynecol., 147(3), 344-354, 20260301
  22. Reirradiation for Recurrent Cervical Cancer Within the Previous Radiation Field Using a Bioabsorbable Spacer: A Case Report., J Obstet Gynaecol Res., 52(3), e70225, 20260306
  23. Progressive MRI changes in lobular endocervical glandular hyperplasia suggesting malignant transformation: report of two cases with histopathologic correlation., Abdom Radiol (NY)., 20260309
  24. Photodynamic diagnosis using 5-aminolevulinic acid for detecting residual ovarian cancer within post-chemotherapy scarring: A case report., Photodiagnosis Photodyn Ther., 20260409
  25. ★, HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma., Int J Cancer., 158(11), 2957-2971, 20260601
  26. Comparison of nedaplatin and cisplatin in concurrent chemoradiotherapy for cervical cancer: a systematic review and meta-analysis, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 31(3), 537-547, 202603
  27. Clinical Characteristics and Predictive Factors of Immune-Mediated Cholangitis: A Large Single-Center Retrospective Observational Study, CANCERS, 18(4), 20260219
  28. Risk stratification of preterm birth using the uterocervical angle and its rate of change in mid- and late-pregnancy: a single-center retrospective study., J Med Ultrason, 20260518