KEN YAMAGUCHI

Last Updated :2026/06/16

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Professor
E-mail
soulkenhiroshima-u.ac.jp
Self-introduction
The discipline of obstetrics and gynecology encompasses four major subspecialties: gynecologic oncology, perinatology, reproductive medicine, and women's healthcare/ My primary focus lies in gynecologic oncology, within which I actively advance the implementation of robotic surgery, digital health technologies, and patient-centered care. In addition, I place strong emphasis on education initiatives designed to ensure that trainees and colleagues are empowered to excel within their respective areas of specialization.

Basic Information

Major Professional Backgrounds

  • 1999/05, 1999/08, Kyoto University, Clinical Resident
  • 1999/09, 1999/11, Clinical Resident
  • 1999/12, 2000/09, Kyoto University, Clinical Resident
  • 2000/10, 2003/03, Japanese Red Cross Otsu Hospital, Doctor
  • 2003/04, 2004/03, Nagahama City Hospital, Doctor
  • 2004/04, 2005/03, Kyoto University, Clinical Fellow
  • 2009/02, 2011/03, Duke University Medical Center
  • 2011/04, 2011/09, Kyoto University
  • 2011/10, 2013/05, Japan Baptist hospital, Doctor
  • 2013/06, 2013/11, Kyoto University
  • 2013/11, 2017/03, Kyoto University, Assistant Professor
  • 2017/04, National Hospital Organization Kyoto Medical Center
  • 2019/03, 2025/03, Kyoto University, Lecturer
  • 2025/06/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Professor

Educational Backgrounds

  • Kyoto University, Japan, 2005/04, 2009/03
  • Osaka City University, School of Medicine, Japan, 1993/04, 1999/03

Academic Degrees

  • Kyoto University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

Research Fields

  • Biological Sciences;Oncology;Tumor biology
  • Biological Sciences;Oncology;Tumor diagnostics
  • Biological Sciences;Oncology;Tumor therapeutics
  • Medicine,dentistry, and pharmacy;Clinical surgery;Obstetrics and gynecology

Affiliated Academic Societies

  • Japan Society of Clinical Genetics in Obstetrics and Gynecology, 2026/02
  • Japanese Society of Female Pelvic Floor Medicine, 2025/11
  • Asian Society for Gynecologic Robotic Surgery, 2025/04
  • Japan Society of Gynecological and Obstetrical Surgery, 2025/04
  • Japan Society for Endoscopic Surgery, 2023/03
  • Japan Society for Menopause and Women's Health, 2020/09
  • Japanese Society of Genetic Counseling, 2019/06
  • Japan Sarcoma Association, 2018/10
  • Japan Society of Human Genetics, 2017/08
  • Japanese Society for Clinical Molecular Morphology, 2017/04
  • Japan Society of Endometriosis, 2017/01
  • Japanese Cancer Association, 2007/09
  • Japan Society of Perinatal and Neonatal Medicine, 2011/11
  • Japan Society of Gynecologic Oncology, 2007/12
  • Japan Society of Clinical Oncology, 2006/04
  • Japan Society of Obstetrics and Gynecology, 1999/04

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, Year, Systemic Disease Control
  2. 2026, Undergraduate Education, Intensive, Practice for medical research
  3. 2026, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2026, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  5. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Obstetrics and Gynecology
  6. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Obstetrics and Gynecology
  7. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Obstetrics and Gynecology
  8. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Obstetrics and Gynecology
  9. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Gynecologic Cancer Treatment
  10. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Gynecologic Cancer Treatment

Research Activities

Academic Papers

  1. ★, HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma., Int J Cancer., 158(11), 2957-2971, 20260601
  2. Risk stratification of preterm birth using the uterocervical angle and its rate of change in mid- and late-pregnancy: a single-center retrospective study., J Med Ultrason, 20260518
  3. Photodynamic diagnosis using 5-aminolevulinic acid for detecting residual ovarian cancer within post-chemotherapy scarring: A case report., Photodiagnosis Photodyn Ther., 20260409
  4. Progressive MRI changes in lobular endocervical glandular hyperplasia suggesting malignant transformation: report of two cases with histopathologic correlation., Abdom Radiol (NY)., 20260309
  5. Reirradiation for Recurrent Cervical Cancer Within the Previous Radiation Field Using a Bioabsorbable Spacer: A Case Report., J Obstet Gynaecol Res., 52(3), e70225, 20260306
  6. Adjuvant Chemotherapy in Stage I Ovarian Clear Cell Carcinoma: A Systematic Review and Meta-analysis., Obstet Gynecol., 147(3), 344-354, 20260301
  7. Clinical Characteristics and Predictive Factors of Immune-Mediated Cholangitis: A Large Single-Center Retrospective Observational Study, CANCERS, 18(4), 20260219
  8. Digital spatial profiling reveals additive effects of triple therapy on tumor microenvironment: anti-PD-L1, anti-VEGF, and PARP inhibition in mouse models., Cancer Immunol Immunother., 75(3), 70, 20260207
  9. Healthcare provider bias in cancer treatment decisions for elderly patients., Taiwan J Obstet Gynecol., 65(1), 29-33, 20260128
  10. Oligoclonal B cell expansion and passenger fusion genes predict response to Nivolumab in recurrent ovarian cancer: phase II Kyoto trial., Cancer Immunol Immunother., 75(2), 52, 20260127
  11. Possible overestimation of treatment effects of pelvic and para-aortic lymphadenectomy for early-stage ovarian clear cell carcinoma: a retrospective propensity-score weighted multi-center cohort study., J Gynecol Oncol., 37(2), e24, 20251224
  12. Real-world application of large language models for automated TNM staging using unstructured gynecologic oncology reports., NPJ Precis Oncol., 9(1), 366, 20251119
  13. High-grade gliomas derived from an ovarian mature teratoma: clonal dynamics and genetic insights., Int Cancer Conf J., 14(4), 421-427, 20250908
  14. Therapeutic impact of neoadjuvant chemotherapy on lymph node metastasis in locally advanced cervical cancer., J Obstet Gynaecol Res., 52(8), e70022, 20250828
  15. Origin of Endometrioid Carcinoma Adjacent to Extraovarian Endometriosis: Detailed Molecular Analyses., Int J Gynecol Pathol., 20250729
  16. Defecation disorder after anterior pelvic exenteration., J Obstet Gynaecol Res., 51(7), e16353, 20250727
  17. A Case of Intramural Adenosarcoma With Sarcomatous Overgrowth Associated With Adenomyosis and Endometriosis., Cureus., 17(7), e88422, 20250721
  18. Usefulness of video explanation for informed consent in gynecologic surgery., Int J Gynaecol Obstet., 20250612
  19. Origin of Peritoneal Cancer With Features of High-grade Serous Carcinoma: A Detailed Molecular Analysis., Int J Gynecol Pathol., 44(3), 280-285, 20250501
  20. Online Live Streaming System for Robotic Surgery With Bidirectional Discussion Through a Commentator: A Multi-Institutional Observational Study., Asian J Endosc Surg., 18(1), e70072, 20250427
  21. A Rare Case of Ovarian Serous Borderline Tumor Recurrence with Muscle Metastasis., Am J Case Rep., 26, e946680, 20250403
  22. Awareness and attitude toward cardio-oncology among Japanese gynecologic oncologists in managing patients with endometrial cancer: The Japanese Gynecologic Oncology Group (JGOG) questionnaire surveys., J Obstet Gynaecol Res., 20250205
  23. Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer., Cancer Immunol Immunother., 74(3), 84, 20250201
  24. ★, Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study., JMIR Cancer., 11, e58093, 20250120
  25. Re-evaluating prognostic factors for cervical cancer with lymph node metastasis: a Japanese multicenter cohort study based on FIGO 2018., Int J Clin Oncol., 20250116
  26. ★, Prognostic significance of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in uterine carcinosarcoma., Int J Clin Oncol., 20250108
  27. Feasibility/clinical utility of half-Fourier single-shot turbo spin echo imaging combined with deep learning reconstruction in gynecologic magnetic resonance imaging., Abdom Radiol (NY)., 20241218
  28. ★, Electronic patient-reported outcomes as digital therapeutics for patients with cancer: a narrative review of current practices and future directions., Int J Clin Oncol., 20241216
  29. Colorectal anastomotic leakage after conversion surgery for advanced endometrial cancer treated with lenvatinib plus pembrolizumab: a case report., Int Cancer Conf J., 14(1), 64-71, 20241210
  30. A stearate-rich diet and oleate restriction directly inhibit tumor growth via the unfolded protein response, Exp Mol Med., 56(12), 2659-2672, 20241202
  31. ★, YAP1 Suppression by ZDHHC7 Is Associated with Ferroptosis Resistance and Poor Prognosis in Ovarian Clear Cell Carcinoma., Mol Cancer Ther., 23(11), 1652-1665, 20241104
  32. Vaginal Cuff Infection Caused by Ureaplasma parvum After Hysterectomy for Uterine Cervical Cancer: A Case Report., Case Rep Infect Dis., 2024, 4114954, 20241021
  33. SMARCA4-deficient uterine tumors in young women: response to immune checkpoint inhibitors., Int Cancer Conf J., 13(4), 515-519, 20240917
  34. A case of grade1 follicular lymphoma diagnosed by laparoscopic lymph node resection: differentiating from late lymph node recurrence of endometrial cancer., Int Cancer Conf J., 13(4), 525-531, 20240917
  35. A case report of mucinous borderline ovarian tumor with recurrence as invasive carcinoma with high copy number alterations., Int Cancer Conf J., 13(4), 520-524, 20240917
  36. Adjuvant Chemotherapy for Stage I Ovarian Clear Cell Carcinoma., O G Open., 1(3), 31, 20240912
  37. Successful correction of the transverse vaginal septum with a pinhole vaginal foramen using Y-V plasty: A case report., Case Rep Womens Health., 42, e00598, 20240327
  38. Clinical significance of initial symptoms in endometriosis-associated ovarian cancer., Turk J Obstet Gynecol., 42(1), 28-36, 20240304
  39. Imiquimod for Cervical and Vaginal Intraepithelial Neoplasia: A Systematic Review and Meta-analysis., Obstet Gynecol., 142(2), 307-318, 20230801
  40. Time-Dependent Changes in Risk of Progression During Use of Bevacizumab for Ovarian Cancer., JAMA Netw Open., 6(8), e2326834, 20230801
  41. Investigation of the Effect of Puncture Order and Position on the Difficulty of Lower and Middle Abdominal Port Placement., Gynecol Minim Invasive Ther., 12(4), 218-224, 20230731
  42. A case of solitary lymph node recurrence 9 years after initial treatment for advanced premenopausal endometrioid endometrial cancer; clinical usefulness of hormonal replacement therapy., Int Cancer Conf J., 12(3), 168-172, 20230310
  43. ★, ATM mutation in aggressive uterine adenosarcoma in which systemic chemotherapies had remarkable effects., Int Cancer Conf J., 12(2), 120-125, 20230112
  44. A case of paraovarian tumor of borderline malignancy with decrease of apparent diffusion coefficient value and marked 18F-fluorodeoxyglucose accumulation., Int Cancer Conf J., 12(2), 126-130, 20221231
  45. Nivolumab for malignant transformation of ovarian mature cystic teratoma., Gynecol Oncol Rep., 44, 101115, 20221210
  46. Immunosuppressive tumor microenvironment in uterine serous carcinoma via CCL7 signal with myeloid-derived suppressor cells., Carcinogenesis., 43(7), 647-658, 20220830
  47. Clinical Features of Neurodevelopmental Outcomes in Children with Preterm Severe Fetal Growth Restriction: A Retrospective Observational Study., JMA J., 5(3), 341-348, 20220715
  48. CXCL13-producing CD4+ T cells accumulate in the early phase of tertiary lymphoid structures in ovarian cancer., JCI Insight., 7(12), e157215, 20220622
  49. Superradical Hysterectomy for Cervical Cancer as an Alternative to the Usual Okabayashi-Type Radical Hysterectomy., Surg J (N Y)., 7(Suppl 2), S108-S114, 20211022
  50. Laparoscopic hysterectomy for endometrial cancer after the Fontan procedure: The first case report., Int Cancer Conf J., 11(1), 41-45, 20211009
  51. Tumor Immune Microenvironment during Epithelial-Mesenchymal Transition., Clin Cancer Res., 27(17), 4669-4679, 20210901
  52. A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis., Case Rep Obstet Gynecol., 2021, 1371611, 20210823
  53. A 36 kg Giant Ovarian Fibroma with Meigs Syndrome: A Case Report and Literature Review of Extremely Giant Ovarian Tumor., Case Rep Obstet Gynecol., 2021, 1076855, 20210815
  54. Combination of gene set signatures correlates with response to nivolumab in platinum-resistant ovarian cancer., Sci Rep., 11(1), 11427, 20210601
  55. ★, Acquired Evolution of Mitochondrial Metabolism Regulated by HNF1B in Ovarian Clear Cell Carcinoma., Cancers (Basel)., 13(10), 2413, 20210517
  56. Sebaceous carcinoma of the vulva treated with sentinel lymph node biopsy: a case report and literature review., Int Cancer Conf J., 10(3), 239-243, 20210505
  57. Three cases of seromucinous carcinoma of the ovary arising in endometriotic cysts., Int Cancer Conf J., 10(1), 46-53, 20200921
  58. UGT1A1 polymorphism has a prognostic effect in patients with stage IB or II uterine cervical cancer and one or no metastatic pelvic nodes receiving irinotecan chemotherapy: a retrospective study., BMC Cancer., 20(1), 729, 20200805
  59. Low-Grade Endometrial Stromal Sarcoma with a Nodule-in-Nodule Appearance in Preoperative Magnetic Resonance Images., Case Rep Obstet Gynecol., 2020, 8973262, 20200730
  60. Full-term low birth weight infants have differentially hypermethylated DNA related to immune system and organ growth: a comparison with full-term normal birth weight infants., BMC Res Notes., 13(1), 199, 20200403
  61. Anti-VEGF therapy resistance in ovarian cancer is caused by GM-CSF-induced myeloid-derived suppressor cell recruitment., Br J Cancer., 122(6), 778-788, 20200114
  62. Acquisition of a side population fraction augments malignant phenotype in ovarian cancer., Sci Rep., 9(1), 14215, 20191002
  63. Phosphorylation of STAT1 serine 727 enhances platinum resistance in uterine serous carcinoma., Int J Cancer., 145(6), 1635-1647, 20190915
  64. ★, Primary retroperitoneal squamous cell carcinoma: a case report with review of the literature., Int Cancer Conf J., 8(2), 61-65, 20190123
  65. The effect of the type of dietary protein on the development of ovarian cancer., Oncotarget., 9(35), 23987-23999, 20180508
  66. Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation., Nat Commun., 9(1), 1685, 20180427
  67. ★, Two cases of recurrent uterine cervical cancer with arterio-enteric fistula treated by femoro-femoral artery bypass in hybrid operation room., Int Cancer Conf J., 7(1), 26-29, 20171031
  68. Four cases of endometrioid borderline ovarian tumour: case reports and literature review., BJR Case Rep., 4(1), 20170062, 20171021
  69. ★, Distinct preoperative clinical features predict four histopathological subtypes of high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum., BMC Cancer., 17(1), 580, 20170829
  70. Combination of Aprepitant, Azasetron, and Dexamethasone as Antiemetic Prophylaxis in Women with Gynecologic Cancers Receiving Paclitaxel/Carboplatin Therapy., Med Sci Monit., 23, 826-833, 20170215
  71. Expression of Vascular Endothelial Growth Factor in Ovarian Cancer Inhibits Tumor Immunity through the Accumulation of Myeloid-Derived Suppressor Cells., Clin Cancer Res., 23(2), 587-599, 20170115
  72. ★, Comprehensive assessment of the expression of the SWI/SNF complex defines two distinct prognostic subtypes of ovarian clear cell carcinoma., Oncotarget., 7(34), 54758-54770, 20160823
  73. Suppression of ABHD2, identified through a functional genomics screen, causes anoikis resistance, chemoresistance and poor prognosis in ovarian cancer., Oncotarget., 7(30), 47620-47636, 20160726
  74. Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer., Cancer Res., 75(23), 5034-5045, 20151201
  75. Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer., J Clin Oncol., 33(34), 4015-4022, 20151201
  76. Genomic profile predicts the efficacy of neoadjuvant chemotherapy for cervical cancer patients., BMC Cancer., 15, 739, 20151019
  77. ★, Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reduction., Oncotarget., 6(31), 30704-30714, 20151013
  78. ★, Epigenetic and genetic dispositions of ovarian carcinomas., Oncoscience., 1(9), 574-579, 20150922
  79. ★, Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival., Oncotarget., 6(28), 26002-26017, 20150922
  80. IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer., Br J Cancer., 112(9), 1501-1509, 20150428
  81. Clinical approaches to treating papillary squamous cell carcinoma of the uterine cervix., BMC Cancer., 14, 784, 20141027
  82. STAT1 drives tumor progression in serous papillary endometrial cancer., Cancer Res., 74(22), 6519-6530, 20141015
  83. ★, Epigenetic determinants of ovarian clear cell carcinoma biology., Int J Cancer., 135(3), 585-597, 20140801
  84. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction., Clin Cancer Res., 19(6), 1363-1374, 20130315
  85. The activated transforming growth factor-beta signaling pathway in peritoneal metastases is a potential therapeutic target in ovarian cancer., Int J Cancer., 130(1), 20-28, 20120101
  86. ★, Ovarian clear cell carcinoma as a stress-responsive cancer: influence of the microenvironment on the carcinogenesis and cancer phenotype., Cancer Lett., 310(2), 129-133, 20111128
  87. Targeting slow-proliferating ovarian cancer cells., Int J Cancer., 126(10), 2448-2456, 20100515
  88. ★, Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes., Oncogene., 29(12), 1741-1752, 20100325
  89. ★, Contents of endometriotic cysts, especially the high concentration of free iron, are a possible cause of carcinogenesis in the cysts through the iron-induced persistent oxidative stress., Clin Cancer Res., 14(1), 32-40, 20080101
  90. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer., Proc Natl Acad Sci U S A., 104(9), 3360-3365, 20070227
  91. Comparison of nedaplatin and cisplatin in concurrent chemoradiotherapy for cervical cancer: a systematic review and meta-analysis, INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 31(3), 537-547, 202603
  92. Real-world application of comprehensive genomic profiling for gynecological malignancies: a multicenter observational study., Int J Clin Oncol., 29(12), 1967-1976, 202412
  93. Proposal for Managing Cancer-Related Insomnia: A Systematic Literature Review of Associated Factors and a Narrative Review of Treatment., Cancer Med., 13(22), e70365, 202411
  94. Investigation of the clinical implications of anterior cervical invasion in locally advanced cervical squamous cell carcinoma., J Obstet Gynaecol Res., 50(9), 1581-1590, 202409
  95. A deep learning-based assessment pipeline for intraepithelial and stromal tumor-infiltrating lymphocytes in high-grade serous ovarian carcinoma., Am J Pathol., 194(7), 1272-1284, 202407
  96. Clinical Significance of Serum SCC Levels Before Treatment for Locally Advanced Cervical Squamous Cell Carcinoma., Anticancer Res., 44(5), 2009-2019, 202405
  97. Neuroendocrine carcinoma of the uterine cervix with extensive pagetoid spread pattern., J Obstet Gynaecol Res., 50(4), 758-763, 202404
  98. Endometrial gastric-type mucinous carcinoma: A clinicopathological study of an unfavorable histological type of endometrial carcinoma., Pathol Int., 73(12), 609-611, 202312
  99. ★, Real-world practice of estrogen and progestogen prescriptions in menopausal women in Japan: A descriptive study using a Japanese claims database., J Obstet Gynaecol Res., 49(12), 2952-2961, 202312
  100. High-grade vaginal intraepithelial neoplasia after hysterectomy for high-grade cervical intraepithelial neoplasia: Is hysterectomy a "definitive" treatment compared to conization?, J Obstet Gynaecol Res., 49(9), 2361-2369, 202309
  101. ★, Hormone replacement therapy and cancer risks in perimenopausal women: A retrospective cohort study using a Japanese claims database., J Obstet Gynaecol Res., 49(7), 1805-1814, 202307
  102. ★, Real-world practice of estrogen therapy after surgery for endometrial cancer: a descriptive study using a Japanese claims database., Int J Clin Oncol., 28(3), 445-453, 202303
  103. Versican provides the provisional matrix for uterine spiral artery dilation and fetal growth., Matrix Biol., 115, 16-31, 202301
  104. Chronic abruption-oligohydramnios sequence (CAOS) revisited: possible implication of premature rupture of membranes., J Matern Fetal Neonatal Med., 35(25), 6894-6900, 202212
  105. Clinical practice guidelines for endometriosis in Japan (The 3rd edition)., J Obstet Gynaecol Res., 48(12), 2993-3044, 202212
  106. ★, Development of healthy lifestyle consciousness index for gynecological cancer patients., Support Care Cancer., 30(9), 7569-7574, 202209
  107. Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics., J Gynecol Oncol., 33(5), e83, 202209
  108. Mutation burden-orthogonal tumor genomic subtypes delineate responses to immune checkpoint therapy., J Immunother Cancer., 10(7), e004831, 202207
  109. Tertiary lymphoid structures are associated with favorable survival outcomes in patients with endometrial cancer., Cancer Immunol Immunother., 71(6), 1431-1442, 202206
  110. MR findings of polypoid endometriosis of female genital organs: report of three cases., Abdom Radiol (NY)., 47(6), 1968-1974, 202206
  111. Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types., JCO Precis Oncol., 6, e2200085, 202205
  112. The effect of celecoxib for treatment of preterm labor on fetuses during the second trimester of pregnancy: A pilot case series., Taiwan J Obstet Gynecol., 61(2), 277-281, 202203
  113. ★, Visceral-to-subcutaneous fat ratio is a possible prognostic factor for type 1 endometrial cancer., Int J Clin Oncol., 27(2), 434-440, 202202
  114. ★, Fertility preservation of polypoid endometriosis: Case series and literature review., J Obstet Gynaecol Res., 48(2), 502-509, 202202
  115. B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression., Cancer Immunol Res., 10(1), 56-69, 202201
  116. Feasibility of Laparoscopic Para-Aortic Lymphadenectomy for Locally Advanced Cervical Cancer., JSLS., 26(1), e2021.00096, 202201
  117. ★, PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma., Cancer Sci., 112(11), 4627-4640, 202111
  118. CT scan assessment of intrauterine balloon tamponade failure for the treatment of atonic postpartum haemorrhage: implications for treatment., BJOG., 128(11), 1726-1731, 202110
  119. A Novel Direct Approach to the Deep Uterine Vein in Laparoscopic Radical Hysterectomy., J Minim Invasive Gynecol., 28(8), 1444-1445, 202108
  120. Survey of the clinical practice pattern of using sentinel lymph node biopsy in patients with gynecological cancers in Japan: the Japan Society of Gynecologic Oncology study., Int J Clin Oncol., 26(5), 971-979, 202105
  121. Potential Novel Ovarian Cancer Treatment Targeting Myeloid-Derived Suppressor Cells., Cancer Invest., 39(4), 310-314, 202104
  122. ★, Serum lactate dehydrogenase is a possible predictor of platinum resistance in ovarian cancer., Obstet Gynecol Sci., 63(6), 709-718, 202011
  123. New method for determining fibrinogen and FDP threshold criteria by artificial intelligence in cases of massive hemorrhage during delivery., J Obstet Gynaecol Res., 46(2), 256-265, 202002
  124. Association between socioeconomic status and small-for-gestational-age in Japan: A single center retrospective cohort study., J Obstet Gynaecol Res., 46(1), 110-118, 202001
  125. Thoracoscopic Resection of Fluorodeoxyglucose-Avid Mediastinal Lymph Nodes Associated with Advanced Ovarian Carcinoma., Thorac Cardiovasc Surg., 67(8), 692-696, 201912
  126. High-intensity breastfeeding improves insulin sensitivity during early post-partum period in obese women with gestational diabetes., Diabetes Metab Res Rev., 35(4), e3127, 201905
  127. ★, Mucinous adenocarcinoma, gastric type of the uterine cervix: clinical features and HER2 amplification., Med Mol Morphol., 52(1), 52-59, 201903
  128. VISTA expressed in tumour cells regulates T cell function., Br J Cancer., 120(1), 115-127, 201901
  129. Prevalence and Risk Factors of Elevated Liver Enzymes in Japanese Women With Polycystic Ovary Syndrome., J Clin Med Res., 10(12), 904-910, 201812
  130. Antitumor Effect of Nivolumab on Subsequent Chemotherapy for Platinum-Resistant Ovarian Cancer., Oncologist., 23(11), 1382-1384, 201811
  131. Invasive Paget's disease of the vulva treated with a combination of surgery and concurrent chemoradiotherapy: A case report., Mol Clin Oncol., 9(5), 489, 201811
  132. Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks., Am J Pathol., 187(10), 2246-2258, 201710
  133. ★, Unenhanced region on magnetic resonance imaging represents tumor progression in uterine carcinosarcoma., J Gynecol Oncol., 28(5), e62, 201709
  134. ★, Groin lymph node detection and sentinel lymph node biopsy in vulvar cancer., J Gynecol Oncol., 27(6), e57, 201611
  135. [Perspectives of Individualized Treatment by Genome-Wide Analyses in Ovarian Cancer]., Gan To Kagaku Ryoho., 43(11), 1316-1320, 201611
  136. Two cases of Wolffian tumor with novel magnetic resonance imaging findings reflecting characteristic pathology., J Obstet Gynaecol Res., 42(8), 1046-1051, 201608
  137. Significance of histologic pattern of carcinoma and sarcoma components on survival outcomes of uterine carcinosarcoma., Ann Oncol., 27(7), 1257-1266, 201607
  138. Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes., Am J Pathol., 186(5), 1103-1113, 201605
  139. ★, Magnetic resonance imaging findings and prognosis of gastric-type mucinous adenocarcinoma (minimal deviation adenocarcinoma or adenoma malignum) of the uterine corpus: Two case reports., Mol Clin Oncol., 4(5), 699-704, 201605
  140. The BMP signaling pathway leads to enhanced proliferation in serous ovarian cancer-A potential therapeutic target., Mol Carcinog., 55(4), 335-345, 201604
  141. Clinical efficacy of neoadjuvant chemotherapy with irinotecan (CPT-11) and nedaplatin followed by radical hysterectomy for locally advanced cervical cancer., J Int Med Res., 44(2), 346-356, 201604
  142. Prediction of taxane and platinum sensitivity in ovarian cancer based on gene expression profiles., Gynecol Oncol., 141(1), 49-56, 201604
  143. Menstrual cyclic change of metastin/GPR54 in endometrium., Med Mol Morphol., 48(2), 76-84, 201506
  144. ★, Hepatocyte nuclear factor-1β (HNF-1β) promotes glucose uptake and glycolytic activity in ovarian clear cell carcinoma., Mol Carcinog., 54(1), 35-49, 201501
  145. Invasion of uterine cervical squamous cell carcinoma cells is facilitated by locoregional interaction with cancer-associated fibroblasts via activating transforming growth factor-beta., Gynecol Oncol., 136(1), 104-111, 201501
  146. Clear cell carcinoma arising from a uterus-like mass., Pathol Int., 64(11), 576-580, 201411
  147. Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib., Cancer Biol Ther., 15(1), 22-25, 201401
  148. A novel diagnostic criterion for lymph node metastasis in cervical cancer using multi-detector computed tomography., Gynecol Oncol., 131(3), 701-707, 201312
  149. Utilization of genomic signatures to identify high-efficacy candidate drugs for chemorefractory endometrial cancers., Int J Cancer., 133(9), 2234-2244, 201310
  150. Ileal perforation and massive intestinal haemorrhage from endometriosis in pregnancy: case report and literature review., Eur J Obstet Gynecol Reprod Biol., 170(1), 20-24, 201309
  151. Expression pattern of Galectin 4 in rat placentation., Placenta., 33(10), 885-887, 201210
  152. ★, Clinical management of ovarian endometriotic cyst(chocolate cyst):diagnosis, medical treatment, and minimally invasive surgery., Curr Obstet Gynecol Rep., 16-24, 201201
  153. Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling., Cancer Sci., 101(12), 2658-2663, 201012
  154. Activated local immunity by CC chemokine ligand 19-transduced embryonic endothelial progenitor cells suppresses metastasis of murine ovarian cancer., Stem Cells., 28(1), 164-173, 201001
  155. ★, Ovarian cancer in endometriosis: molecular biology, pathology, and clinical management., Int J Clin Oncol., 14(5), 383-391, 200910
  156. Clinical significance of the NKG2D ligands, MICA/B and ULBP2 in ovarian cancer: high expression of ULBP2 is an indicator of poor prognosis., Cancer Immunol Immunother., 58(5), 641-652, 200905
  157. ★, Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period., Oncol Rep., 19(3), 705-711, 200803
  158. Immunostimulatory effect of Fms-like tyrosine kinase 3 ligand on peripheral monocyte-derived dendritic cells and natural killer cells: utilization for ovarian cancer treatment., Oncol Rep., 19(2), 505-515, 200802
  159. Immortalized ovarian surface epithelial cells acquire tumorigenicity by Acrogranin gene overexpression., Oncol Rep., 17(2), 329-333, 200702
  160. ★, Postpartum hemorrhage is associated with neonatal body weight, pre-pregnancy body mass index, and maternal weight gain., Clin. Exp. Obstet. Gynecol., 47(6), 820-925, 2020
  161. Association of Dietary Change during Pregnancy with Large-for-Gestational Age Births: A Prospective Observational Study., J Nutr Sci Vitaminol (Tokyo)., 66(3), 246-254, 2020
  162. Tight systolic blood pressure control early in pregnancy improves pregnancy outcomes in women with chronic hypertension., Hypertension Research in Pregnancy., 7(2), 75-81, 2019