Toshiki DOI

Last Updated :2021/01/05

Affiliations, Positions
Hiroshima University Hospital(Medical), Contributing Professor

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2006/04, 2014/05
  • Hiroshima University, Faculty of Medicine, Japan, 1993/04, 1999/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Kidney internal medicine

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Intensive, Introduction to clinical clerkship

Research Activities

Academic Papers

  1. Oral mizoribine pulse therapy for steroid-dependent focal segmental glomerulosclerosis., Clinical Nephrology, 69(6), 433-435
  2. How do dialysis physicians use and evaluate the guidelines for dialysis initiation?, Journal of Japanese Society for Dialysis Therapy, 42(11), 879-884
  3. PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta., Laboratory Investigation, 89(1), 47-58
  4. Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta 1 signaling, KIDNEY INTERNATIONAL, 84(2), 297-307, AUG 2013
  5. Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats, PLOS ONE, 9(4), APR 2 2014
  6. Expression of age-related factors during the development of renal damage in patients with IgA nephropathy., Clinical and Experimental Nephrology, 19(5), 830-837
  7. The serum lipids levels may be underestimated in patients on hemodialysis., Internal Medicine, 54(8), 887-894
  8. Risk Score to Predict 1-Year Mortality after Haemodialysis Initiation in Patients with Stage 5 Chronic Kidney Disease under Predialysis Nephrology Care., PLoS One, 10(6), e0129180
  9. Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression., Kidney International, 89(1), 147-157
  10. Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis., Journal of the American Society of Nephrology, 27(1), 203-215
  11. High glucose promotes TGF-beta1 production by inducing FOS expression in human peritoneal mesothelial cells., Clinical and Experimental Nephrology, 20(1), 30-38
  12. Valproic acid attenuates renal fibrosis through the induction of autophagy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 21(5), 771-780, OCT 2017
  13. Protective Effects of Japanese Soybean Paste (Miso) on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP), AMERICAN JOURNAL OF HYPERTENSION, 31(1), 43-47
  14. Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 315(2), F300-F312, AUG 2018
  15. Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction., PLoS One., 13(8), e0202409, 2018, 8, 18
  16. Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction, PLOS ONE, 13(8), AUG 16 2018
  17. Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a, Kidney International
  18. High-normal albuminuria is associated with subclinical atherosclerosis in male population with estimated glomerular filtration rate ≥60 mL/min/1.73 m2: A cross-sectional study, PLoS One, e0218290