広島大学

Basic Information

Educational Backgrounds

• Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2006/04, 2014/05
• Hiroshima University, Faculty of Medicine, Japan, 1993/04, 1999/03

Academic Degrees

• Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

• Medicine,dentistry, and pharmacy;Clinical internal medicine;Kidney internal medicine

Educational Activity

Course in Charge

1. 2024, Undergraduate Education, Year, Clinical diagnosis and treatment I
2. 2024, Undergraduate Education, Intensive, Practice of Medicine II

Research Activities

Academic Papers

1. Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta 1 signaling, KIDNEY INTERNATIONAL, 84(2), 297-307, 201308
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2. Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats, PLOS ONE, 9(4), 20140402
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3. Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression., Kidney International, 89(1), 147-157
4. Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis., Journal of the American Society of Nephrology, 27(1), 203-215
5. High glucose promotes TGF-beta1 production by inducing FOS expression in human peritoneal mesothelial cells., Clinical and Experimental Nephrology, 20(1), 30-38
6. The serum lipids levels may be underestimated in patients on hemodialysis., Internal Medicine, 54(8), 887-894
7. Expression of age-related factors during the development of renal damage in patients with IgA nephropathy., Clinical and Experimental Nephrology, 19(5), 830-837
8. PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta., Laboratory Investigation, 89(1), 47-58
9. Oral mizoribine pulse therapy for steroid-dependent focal segmental glomerulosclerosis., Clinical Nephrology, 69(6), 433-435
10. Risk Score to Predict 1-Year Mortality after Haemodialysis Initiation in Patients with Stage 5 Chronic Kidney Disease under Predialysis Nephrology Care., PLoS One, 10(6), e0129180
11. How do dialysis physicians use and evaluate the guidelines for dialysis initiation?, Journal of Japanese Society for Dialysis Therapy, 42(11), 879-884
12. Valproic acid attenuates renal fibrosis through the induction of autophagy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 21(5), 771-780, 201710
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13. Protective Effects of Japanese Soybean Paste (Miso) on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP), AMERICAN JOURNAL OF HYPERTENSION, 31(1), 43-47
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14. Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 315(2), F300-F312, 201808
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15. Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction., PLoS One., 13(8), e0202409, 20180818
16. Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction, PLOS ONE, 13(8), 20180816
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17. Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a, Kidney International
18. High-normal albuminuria is associated with subclinical atherosclerosis in male population with estimated glomerular filtration rate ≥60 mL/min/1.73 m2: A cross-sectional study, PLoS One, e0218290