Hitoshi Komatsuzawa
Last Updated :2023/06/01
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Professor
- E-mail
- komatsuz
hiroshima-u.ac.jp
- Self-introduction
- Bacteriology is important for the understanding oral and systemic infectious diseases.Regarding to bacterial research, we are studying 1) Pathogenicity and antibiotic resistance of antibiotic resistant bacteria, 2)Pathogenicity of cariogenic and periodontopathogenic bacteria, 3)Formation of oral microbiome.
Basic Information
Major Professional Backgrounds
- 1992/10/01, 2000/05/31, Hiroshima University, School of Dentistry, Research Associate
- 2000/06/01, 2002/03/31, Hiroshima University, School of Dentistry, Associate Professor
- 2002/04/01, 2008/02/29, Hiroshima University, Graduate School of Biomedical & Health Sciences, Associate Professor
- 2008/03/01, 2019/04/30, Kagoshima University, Professor
- 2019/05/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Professor
Academic Degrees
Educational Activity
- [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
- [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences
Educational Activity
Course in Charge
- 2023, Liberal Arts Education Program1, 2Term, General Health and Oral Sciences I
- 2023, Undergraduate Education, Year, Biological Responses
- 2023, Undergraduate Education, 4Term, Life Science
- 2023, Undergraduate Education, 3Term, Microbiology I
- 2023, Undergraduate Education, 4Term, Microbiology II
- 2023, Undergraduate Education, First Semester, Basic Technique for Microbiology and Immunology
- 2023, Undergraduate Education, 3Term, Examination and Diagnosis
- 2023, Undergraduate Education, 3Term, Endodontics I
- 2023, Undergraduate Education, 4Term, Endodontics II
- 2023, Undergraduate Education, 3Term, Periodontology I
- 2023, Undergraduate Education, First Semester, Dental Research Practices I
- 2023, Undergraduate Education, Second Semester, Dental Research Practices II
- 2023, Undergraduate Education, 2Term, Basic and clinical integrated theory
- 2023, Undergraduate Education, First Semester, Dental Research Practices III
- 2023, Undergraduate Education, 2Term, Dental Research Practices IV
- 2023, Undergraduate Education, 1Term, Microbiology and Oral Microbiology
- 2023, Undergraduate Education, Second Semester, Practice on Basic Dental Sciences
- 2023, Undergraduate Education, 1Term, Microbiology and Oral Microbiology
- 2023, Graduate Education (Master's Program) , First Semester, Seminar
- 2023, Graduate Education (Master's Program) , Second Semester, Seminar
- 2023, Graduate Education (Master's Program) , First Semester, Research
- 2023, Graduate Education (Master's Program) , Second Semester, Research
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
- 2023, Graduate Education (Master's Program) , 3Term, Seminar on Host Defense
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Bacteriology
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Bacteriology
- 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Bacteriology
- 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Bacteriology
Research Activities
Academic Papers
- ★, Single mutations in BraRS confer high resistance against nisin A in Staphylococcus aureus., MicrobiologyOpen, 17, e791, 20190117
- Antibacterial activity of disodium succinoyl glycyrrhetinate, a derivative of glycyrrhetinic acid against Streptococcus mutans., Microbiology and Immunology, 63(7), 251-260
- Heparin-LL37 complexes are less cytotoxic for human dental pulp cells and have undiminished antimicrobial and LPS-neutralizing abilities., Int Endod J, 52(9), 1327-1343
- Small RNA repertoires and their intraspecies variation in Aggregatibacter actinomycetemcomitans., DNA Res., 25(2), 207-215
- Impact of a 7-Day field training on oral health condition in Japan ground self-defense force personnel., Mil Med., 182(7), e1869-e1877
- Recombinant Sox enzymes from Paracoccus pantotrophus degrade hydrogen sulfide, a major component of oral malodor., Microbes Environ., 32(1), 54-60
- Significant increase of oral bacteria in the early pregnancy period in Japanese women. J Investig, Clin Dent., 8, e12189
- Antibacterial effects of glycyrrhetinic acid and its derivatives on Staphylococcus aureus., PLoS One., 11(11), e0165831
- Lysine and threonine biosynthesis from aspartate contributes to Staphylococcus aureus growth in calf serum., Appl Environ Microbiol, 82(20), 6150-6157
- ★, Two-component systems involved in susceptibility to nisin A in Streptococcus pyogenes. 82(19):5930-5939, 2016, Appl Environ Microbiol., 82(19), 5930-5939
- Staphylococcus aureus SrrAB affects susceptibility to hydrogen peroxide and co-existence with Streptococcus sanguinis., PLoS One, 11(7), e0159768
- Aggregatibacter actinomycetemcomitans outer membrane protein 29 (Omp29) induces TGF-β-regulated apoptosis signal in human gingival epithelial cells via fibronectin/integrinβ1/FAK cascade., Cell Microbiol., 18(12), 1723-1738
- C55 bacteriocin produced by ETB-plasmid positive Staphylococcus aureus strains is a key factor for competition with S. aureus strains. 2016 Mar;60(3):139-147, 2016, Microbiol Immunol., 60(3), 139-147
- LL37 induces VEGF expression in dental pulp cells through ERK signalling. 48(7):673-679, Int Endod J., 48(7), 673-679
- The antimicrobial peptide LL37 promotes bone regeneration in a rat calvarial bone defect., Peptides, 46, 136-142
- Three distinct two-component systems are involved in resistance to the class I bacteriocins, Nukacin ISK-1 and nisin A, in Staphylococcus aureus., PLoS One, 22(8), e69455
- Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans., Appl Environ Microbiol., 79(15), 4751-4755
- ★, Staphylococcus aureus SasA is responsible for binding to salivary agglutinin, gp340, derived from human saliva., Infect Immun., 81(6), 1870-1879
- ★, The S-layer of Tannerella forsythia contributes to serum resistance and oral bacterial co-aggregation., Infect Immun., 81(4), 1198-1206
- Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cells., J Periodontal Res., 48(2), 228-234
- ★, dpr and sod in Streptococcus mutans are involved in coexistence with S. sanguinis, and PerR is associated with resistance to H2O2., Appl Environ Microbiol., 79(5), 1436-1443
- ★, GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence., PLoS One, 7(3), e33382
- ★, Association of CiaRH with resistance of Streptococcus mutans to antimicrobial peptides in biofilms. 27(2):124-135, 2012, Mol Oral Microbiol., 27(2), 124-135
- ★, Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus, , Microbiology, 157, 1786-1797
- Lipopolysaccharides mediate leukotoxin secretion in Aggregatibacter actinomycetemcomitans., Mol Oral Microbiol., 27(2), 70-82
- Detection of Fusobacterium nucleatum in chorionic tissues of high-risk pregnant women., J Clin Periodontol., 39(5), 417-424
- ★, Expressions of virulence factors in Staphylococcus aureus grown in serum., Appl Environ Microbiol., 77(22), 8097-8105
- ★, Bacitracin sensing and resistance in Staphylococcus aureus., FEMS Microbiol Lett., 320(1), 33-39
- MK615: a new therapeutic approach for the treatment of oral disease., Med Hypotheses., 77(2), 258-260
- Aggregatibacter actinomycetemcomitans Omp29 is associated with bacterial entry to gingival epithelial cells by F-actin rearrangement., PLoS One, 29(6), e18287
- Regulatory mechanism for exfoliative toxin production in Staphylococcus aureus. 79(4):1660-1670, 2011, Infect Immun., 79(4), 1660-1670
- Additive effects of orexin B and vasoactive intestinal polypeptide on LL-37-mediated antimicrobial activities. 233(1-2):37-45, 2011, J Neuroimmunol., 233(1-2), 37-45
- Distinct two-component systems in methicillin-resistant Staphylococcus aureus can change the susceptibility to antimicrobial agents., J Antimicrob Chemother., 65(7), 1536-1537
- The antimicrobial peptide LL37 induces the migration of human pulp cells: a possible adjunct for regenerative endodontics. 36(6):1009-1013, 2010, J Endod., 36(6), 1009-1013
- Automutanolysin disrupts clinical isolates of cariogenic streptococci in biofilms and planktonic cells., Oral Microbiol Immunol., 24, 451-455
- ★, Increased resistance to cationic antimicrobial peptide LL-37 in methicillin-resistant strains of Staphylococcus aureus., J Antimicrob Chemother., 61(6), 1266-1269
- Cytolethal distending toxin induces caspase-dependent and -independent cell death in MOLT-4 cells., Infect Immun., 76, 4783-4791
- Irsogladine maleate abolishes the increase in interleukin-8 levels caused by outer membrane protein 29 from Aggregatibacter (Actinobacillus) actinomycetemcomitans through the ERK pathway in human gingival epithelial cells., J Periodontal Res., 43, 508-513
- First isolation of blaIMP-7 in a Pseudomonas aeruginosa in Japan. 13(4):276-7, 2007, J Infect Chemother., 13(4), 276-277
- CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes., Int. Immunol., 19(9), 1095-1102
- Cross-reactive adaptive immune response to oral commensal bacteria results in an induction of receptor activator of nuclear factor-kappaB ligand (RANKL)-dependent periodontal bone resorption in a mouse model. Oral Microbiol Immunol. (Mol. Oral Microbiol.), Oral Microbiol Immunol. (Mol. Oral Microbiol.), 22(3), 208-215
- Molecular characterization of imipenem-resistant Pseudomonas aeruginosa in Hiroshima, Japan., Microbiol Immunol., 51(3), 271-277
- Kawai T: Innate immune peptide LL-37 displays distinct expression pattern from beta-defensins in inflamed gingival tissue., Clin Exp Immunol., 146(2), 218-225
- ★, Actinobacillus actinomycetemcomitans outer membrane protein 100 triggers innate immunity and production of beta-defensin and the 18-kilodalton cationic antimicrobial protein through the fibronectin-integrin pathway in human gingival epithelial cells., Infect Immun., 74(9), 5211-5220
- Identification and molecular characterization of an N-Acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation., Microbiol Immunol., 50(9), 729-742
- Single nucleotide polymorphism in the cytolethal distending toxin B gene confers heterogeneity in the cytotoxicity of Actinobacillus actinomycetemcomitans., Infect Immun., 74(12), 7014-7020
- Biogenesis of the Actinobacillus actinomycetemcomitans cytolethal distending toxin holotoxin. 74:3480-3487, 2006, Infect Immun., 74, 3480-3487
- Identification and molecular characterization of an N-acetylmuramyl-L-alanine amidase Sle1 involved in cell separation of Staphylococcus aureus. Mol Microbiol. 58(4):1087-1101, 2005, 58(4), 1087-1101
- Cell wall-targeting domain of glycylglycine endopeptidase distinguishes among peptidoglycan cross-bridges., J Biol Chem., 28(1), 549-558
- Staphylococcus hyicus exfoliative toxins selectively digest porcine desmoglein 1., Microb Pathog., 39(5-6), 171-176
- Induction of keratinocyte migration via transactivation of the EGF receptor by the antimicrobial peptide LL37., J Immunol., 175, 4662-4668
- Irsogladine maleate influences the response of gap junctional intercellular communication and IL-8 of human gingival epithelial cells following periodontopathogenic bacterial challenge. 333(2):502-507,2005, Biochem Biophys Res Commun., 333(2), 502-507
- ★, Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, beta-defensins and LL37, produced by human epithelial cells., J Antimicrob Chemother., 55(6), 888-896
- New mechanisms of skin innate immunity: ASK1-mediated keratinocyte differentiation regulates the expression of beta-defensins, LL37, and TLR2., Eur J Immunol., 35(6), 1886-1895
- Mutation analysis of the histidine residues in the glycylglycine endopeptidase ALE-1., J Bacteriol., 187(2), 480-487
- ★, Reduced content of lysyl-phosphatidylglycerol in the cytoplasmic membrane affects susceptibility to moenomycin, as well as vancomycin, gentamicin, and antimicrobial peptides, in Staphylococcus aureus. 48(12):4800-4807,2004, Antimicrob Agents Chemother., 48(12), 4800-4807
- The gate controlling cell wall synthesis in Staphylococcus aureus., Mol Microbiol., 53(4), 1221-1231
- Zymographic characterization of bacteriolytic enzymes produced by oral streptococci., Microbiol Immunol., 48(6), 465-469
- Syntheses of prostaglandin E2 and E-cadherin and gene expression of beta-defensin-2 by human gingival epithelial cells in response to Actinobacillus actinomycetemcomitans., Inflammation., 27(6), 341-349
- ★, Moenomycin-resistance is associated with vancomycin-intermediate susceptibility in Staphylococcus aureus., Microbiol Immunol., 47(12), 927-935
- ★, Outer membrane protein 100, a versatile virulence factor of Actinobacillus actinomycetemcomitans., Mol Microbiol., 50(4), 1125-1139
- Enhancement of alkaline phosphatase synthesis in pulp cells co-cultured with epithelial cells derived from lower rabbit incisors., Cell Biol Int., 27(10), 815-823
- An N-terminal segment of the active component of the bacterial genotoxin cytolethal distending toxin B (CDTB) directs CDTB into the nucleus., J Biol Chem., 278(50), 50671-50681
- Macrophage inflammatory protein-3alpha and beta-defensin-2 stimulate dentin sialophosphoprotein gene expression in human pulp cells., Biochem Biophys Res Commun., 306(4), 867-871
- ★, Staphylococcus aureus susceptibility to innate antimicrobial peptides, beta-defensins and CAP18, expressed by human keratinocytes., Infect Immun., 71(7), 3730-3739
- Prevalence of cytolethal distending toxin production in periodontopathogenic bacteria., J Clin Microbiol., 41(4), 1391-1398
- Molecular characterization of an atl null mutant of Staphylococcus aureus., Microbiol Immunol., 46(9), 601-612
- Antibacterial activity of disodium succinoyl glycyrrhetinate, a derivative of glycyrrhetinic acid against Streptococcus mutans., Microbiol Immunol., 63(7), 251-260, 201907
- ★, Staphylococcus aureus Virulence Affected by an Alternative Nisin A Resistance Mechanism, Appl Environ Microbiol, 86 1;86(8):e02923-19.(8), e02923, 20200401
- Antibacterial activity of phellodendron bark against Streptococcus mutans., Microbiol Immunol., 64(6), 424-434, 202006
- Rapid detection of the Streptococcus mutans cnm gene by loop-mediated isothermal amplification., Anal Biochem., 15(605), 113812, 202009
- Biogenesis of the Actinobacillus actinomycetemcomitans cytolethal distending toxin holotoxin, INFECTION AND IMMUNITY, 74(6), 3480-3487, 2006
- Identification and molecular characterization of an N-acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation, MICROBIOLOGY AND IMMUNOLOGY, 50(9), 729-742, 2006
- Actinobacillus actinomycetemcomitans outer membrane protein 100 triggers innate immunity and production of beta-defensin and the 18-kilodalton cationic antimicrobial protein through the fibronectin-integrin pathway in human gingival epithelial cells, INFECTION AND IMMUNITY, 74(9), 5211-5220, 2006
- Single nucleotide polymorphism in the cytolethal distending toxin B gene confers heterogeneity in the cytotoxicity of Actinobacillus actinomycetemcomitans, INFECTION AND IMMUNITY, 74(12), 7014-7020, 2006
- Molecular characterization of imipenem-resistant Pseudomonas aeruginosa in Hiroshima, Japan, MICROBIOLOGY AND IMMUNOLOGY, 51(3), 271-277, 2007
- Susceptibility of periodontopathogenic and cariogenic bacteria to Defensins and potential therapeutic use of Defensins in oral diseases, CURRENT PHARMACEUTICAL DESIGN, 13(30), 3084-3095, 2007
- CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes, INTERNATIONAL IMMUNOLOGY, 19(9), 1095-1102, 2007
- Increased resistance to cationic antimicrobial peptide LL-37 in methicillin-resistant strains of Staphylococcus aureus, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 61(6), 1266-1269, 2008
- Cytolethal distending toxin induces caspase-dependent and -independent cell death in MOLT-4 cells, INFECTION AND IMMUNITY, 76(10), 4783-4791, 2008
- The Antimicrobial Peptide LL37 Induces the Migration of Human Pulp Cells: A Possible Adjunct for Regenerative Endodontics, JOURNAL OF ENDODONTICS, 36(6), 1009-1013, 2010
- Distinct two-component systems in methicillin-resistant Staphylococcus aureus can change the susceptibility to antimicrobial agents, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 65(7), 1536-1537, 2010
- Regulatory Mechanism for Exfoliative Toxin Production in Staphylococcus aureus, INFECTION AND IMMUNITY, 79(4), 1660-1670, 2011
- Aggregatibacter actinomycetemcomitans Omp29 Is Associated with Bacterial Entry to Gingival Epithelial Cells by F-Actin Rearrangement, PLOS ONE, 6(4), 2011
- Additive effects of orexin B and vasoactive intestinal polypeptide on LL-37-mediated antimicrobial activities, JOURNAL OF NEUROIMMUNOLOGY, 233(1-2), 37-45, 2011
- Bacitracin sensing and resistance in Staphylococcus aureus, FEMS MICROBIOLOGY LETTERS, 320(1), 33-39, 2011
- Growth-phase dependence of susceptibility to antimicrobial peptides in Staphylococcus aureus, MICROBIOLOGY-SGM, 157, 1786-1797, 2011
- MK615: A new therapeutic approach for the treatment of oral disease, MEDICAL HYPOTHESES, 77(2), 258-260, 2011
- Expression of Virulence Factors by Staphylococcus aureus Grown in Serum, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 77(22), 8097-8105, 2011
- Role of two-component systems in the resistance of Staphylococcus aureus to antibacterial agents, VIRULENCE, 2(5), 427-430, 2011
- Detection of Fusobacterium nucleatum in chorionic tissues of high-risk pregnant women, JOURNAL OF CLINICAL PERIODONTOLOGY, 39(5), 417-424, 2012
- GlmS and NagB Regulate Amino Sugar Metabolism in Opposing Directions and Affect Streptococcus mutans Virulence, PLOS ONE, 7(3), 2012
- dpr and sod in Streptococcus mutans Are Involved in Coexistence with S. sanguinis, and PerR Is Associated with Resistance to H2O2, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(5), 1436-1443, 2013
- The Surface Layer of Tannerella forsythia Contributes to Serum Resistance and Oral Bacterial Coaggregation, INFECTION AND IMMUNITY, 81(4), 1198-1206, 2013
- Staphylococcus aureus SasA Is Responsible for Binding to the Salivary Agglutinin gp340, Derived from Human Saliva, INFECTION AND IMMUNITY, 81(6), 1870-1879, 2013
- Involvement of the Novel Two-Component NsrRS and LcrRS Systems in Distinct Resistance Pathways against Nisin A and Nukacin ISK-1 in Streptococcus mutans, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(15), 4751-4755, 2013
- Three Distinct Two-Component Systems Are Involved in Resistance to the Class I Bacteriocins, Nukacin ISK-1 and Nisin A, in Staphyloccus aureus, PLOS ONE, 8(7), 2013
- The antimicrobial peptide LL37 promotes bone regeneration in a rat calvarial bone defect, PEPTIDES, 46, 136-142, 2013
- C55 bacteriocin produced by ETB-plasmid positive Staphylococcus aureus strains is a key factor for competition with S-aureus strains, MICROBIOLOGY AND IMMUNOLOGY, 60(3), 139-147, 2016
- Staphylococcus aureus SrrAB Affects Susceptibility to Hydrogen Peroxide and Co-Existence with Streptococcus sanguinis, PLOS ONE, 11(7), 2016
- Two-Component Systems Involved in Susceptibility to Nisin A in Streptococcus pyogenes, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(19), 5930-5939, 2016
- Lysine and Threonine Biosynthesis from Aspartate Contributes to Staphylococcus aureus Growth in Calf Serum, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(20), 6150-6157, 2016
- Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus, PLOS ONE, 11(11), 2016
- Aggregatibacter actinomycetemcomitans outer membrane protein 29 (Omp29) induces TGF--regulated apoptosis signal in human gingival epithelial cells via fibronectin/integrin1/FAK cascade, CELLULAR MICROBIOLOGY, 18(12), 1723-1738, 2016
- Sugar Allocation to Metabolic Pathways is Tightly Regulated and Affects the Virulence of Streptococcus mutans, GENES, 8(1), 2017
- Recombinant Sox Enzymes from Paracoccus pantotrophus Degrade Hydrogen Sulfide, a Major Component of Oral Malodor, MICROBES AND ENVIRONMENTS, 32(1), 54-60, 2017
- Impact of a 7-Day Field Training on Oral Health Condition in Japan Ground Self-Defense Force Personnel, MILITARY MEDICINE, 182(7), E1869-E1877, 2017
- Small RNA repertoires and their intraspecies variation in Aggregatibacter actinomycetemcomitans, DNA RESEARCH, 25(2), 207-215, 2018
- Antibacterial activity of disodium succinoyl glycyrrhetinate, a derivative of glycyrrhetinic acid against Streptococcus mutans, MICROBIOLOGY AND IMMUNOLOGY, 63(7), 251-260, 2019
- Single mutations in BraRS confer high resistance against nisin A in Staphylococcus aureus, MICROBIOLOGYOPEN, 8(11), 2019
- Staphylococcus aureus Virulence Affected by an Alternative Nisin A Resistance Mechanism, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 86(8), 2020
- Antibacterial activity of phellodendron bark against Streptococcus mutans, MICROBIOLOGY AND IMMUNOLOGY, 64(6), 424-434, 2020
- Rapid detection of the Streptococcus mutans cnm gene by loop-mediated isothermal amplification, ANALYTICAL BIOCHEMISTRY, 605, 2020
- Expression of virulence factors under different environmental conditions in Aggregatibacter actinomycetemcomitans, MICROBIOLOGY AND IMMUNOLOGY, 2021
- Periodontitis and the outcome of atrial fibrillation ablation: Porphyromonas gingivalis is related to atrial fibrillation recurrence, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2021
Publications such as books
- 2019/02/20, Oral microbiology and Immunology, Textbook, Compilation, 日本語, ISBN978-4-263-45791-7, 303, 28
Invited Lecture, Oral Presentation, Poster Presentation
- Complete sequences of bacteriocin plasmids of S. epidermidis and their antibacterial activity, 2022/03/29, Without Invitation, Japanese
- Isolation and characterization of oral antibiotic-resistant Gram-negative bacteria in the long-term care facility, Azusa Haruta, Miki Matsuo, Mineka Yoshikawa, Maho Takeuchi, Le Nguyen Tra Mi, Koji Yahara, Toshiki Kajihara, Syoko Kutsuno, Hiroki Ohge, Kazuhiro Tsuga, Motoyuki Sugai, Hitoshi Komatsuzawa, MIRAI 2.0 Digital Research and Innovation Week, 2021/06/07, Without Invitation, English
- Isolation and characterization of oral antibiotic-resistant Gram-negative bacteria in the long-term care facility, Azusa Haruta, Miki Matsuo, Mineka Yoshikawa, Maho Takeuchi, Le Nguyen Tra Mi, Koji Yahara, Toshiki Kajihara, Syoko Kutsuno, Hiroki Ohge, Kazuhiro Tsuga, Motoyuki Sugai, Hitoshi Komatsuzawa, The 6th JSMid, 2021/08/01, Without Invitation, English
- Evaluation of high resistant mechanism against nisin A in nisin A high resistant MRSA, 2019/10/12, Without Invitation, Japanese, preprint
- Effect of plant-derived extract , Phellodendron bark, against cariogenic bacteria, 2020/02/21, Without Invitation, Japanese, preprint
- Characterization of bacteriocin-KO mutants in S. mutans, 2020/02/21, Without Invitation, Japanese, preprint
- Skillful survival strategies with two-component systems of commensal bacteria against human- and bacterial-derived antimicrobial peptides, 2020/02/21, With Invitation, Japanese, preprint
- Survival strategy of Staphylococcus aureus in the host, Komatsuzawa H, 2019/10/04, With Invitation, Japanese, preprint
External Funds
Acceptance Results of Competitive Funds
- Development of novel prevention method for dental caries by bacteriophage, 2020, 2021
- Grants-in-Aid for Scientific Research, 2016, 2018
- Grants-in Aid for Scientific research (C), 2013, 2015
- 2007, 2008
- 2007, 2008