Naoki Isobe

Last Updated :2024/07/04

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor
Web Site
http://anat.hiroshima-u.ac.jp/english2/
https://www.youtube.com/watch?v=AD10JVAmd3I
https://gsbstop.hiroshima-u.ac.jp/taidan/en/vol3.html
E-mail
nisohiroshima-u.ac.jp
Other Contact Details
1-4-4 HIGASHI-HIROSHIMA, Japan
TEL : (+81)82-424-7993 FAX : (+81)82-424-7993
Self-introduction
My research aims to prevent mastitis in dairy cows. I found that various antimicrobial components are synthesized in different sites of udder and that they cooperatively remove pathogens. I proposed method decreasing frequency of milking for new mastitis treatment. I elucidated that mastitis can be caused by not only viable bacteria but also bacterial components translocated from other organs.

Basic Information

Major Professional Backgrounds

  • 1996/08/01, 2005/03/31, Hiroshima University, Graduate School for International Development and Cooperation, Research Associate
  • 2016/09/26, 2017/09/26, Gadjah Mada University, Faculty of Agriculture, Visiting professor

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Biophere Sciences, Japan, 1993/04, 1996/03
  • Hiroshima University, Faculty of Applied Biological Science, Japan, 1987/04, 1991/03

Academic Degrees

  • Doctor of Agriculture, Hiroshima University
  • Master of Agriculture, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Applied Biological Science : Department of Applied Biological Science : Applied Animal and Plant Science Program
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Bioresource Science
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Bioresource Science

In Charge of Primary Major Programs

  • Applied Animal and Plant Science Program

Research Fields

  • Agricultural sciences;Animal life science;Animal production science

Research Keywords

  • mammary gland
  • EIA
  • Somatic cell count
  • immunohistochemistry
  • hormone
  • milk
  • feces
  • Mastitis
  • Innate immunity
  • Antimicrobial peptide

Affiliated Academic Societies

  • Japanese Society of Veterinary Science, 2016
  • The American Dairy Science Association, 2009
  • Japanese Association of Animal Science, 1990
  • Japanese Association of Animal Reproduction, 1993
  • Japanese Association of Mastitis, 2006
  • Kansai Association of Animal Science, 1990
  • Chushikoku Mastitis Council, 2013

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 1Term, Introduction to Applied Biological Sciences toward SDGs
  2. 2024, Undergraduate Education, 1Term, Introduction to Applied Biological Sciences
  3. 2024, Undergraduate Education, Intensive, Laboratory Work in General Biology II
  4. 2024, Undergraduate Education, 1Term, Introduction to Physiology
  5. 2024, Undergraduate Education, 3Term, Research Front of Bioresource Science
  6. 2024, Undergraduate Education, 3Term, Animal Functional Anatomy
  7. 2024, Undergraduate Education, 1Term, Animal Physiology and Production
  8. 2024, Undergraduate Education, Intensive, Laboratory and Field Works in Animal Production I
  9. 2024, Undergraduate Education, 2Term, Reading of Foreign Literature in Applied Animal and Plant Schience
  10. 2024, Undergraduate Education, Intensive, Topics in Applied Animal and Plant Science III
  11. 2024, Undergraduate Education, Second Semester, Graduation Thesis I
  12. 2024, Undergraduate Education, First Semester, Graduation Thesis II
  13. 2024, Undergraduate Education, Second Semester, Graduation Thesis III
  14. 2024, Undergraduate Education, Intensive, Life, food and agricultural education through experimental studies of dairy farming
  15. 2024, Undergraduate Education, Intensive, (AIMS) Introduction Physiology of Domestic Animals
  16. 2024, Undergraduate Education, 3Term, Introductory Physiology of Domestic Animals
  17. 2024, Graduate Education (Master's Program) , 1Term, Exercises in Bioresource Science A
  18. 2024, Graduate Education (Master's Program) , 2Term, Exercises in Bioresource Science A
  19. 2024, Graduate Education (Master's Program) , 3Term, Exercises in Bioresource ScienceB
  20. 2024, Graduate Education (Master's Program) , 4Term, Exercises in Bioresource ScienceB
  21. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Bioresource Science
  22. 2024, Graduate Education (Master's Program) , 2Term, Animal Production Science I
  23. 2024, Graduate Education (Master's Program) , 4Term, Animal Production Science II
  24. 2024, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences

Research Activities

Academic Papers

  1. Innate Immune Training in Chickens for Improved Defense against Pathogens: A Review, JOURNAL OF POULTRY SCIENCE, 61, 2024
    Link to Paper Search Results by DOI
  2. Effect of sodium butyrate treatment at the basolateral membranes on the tight junction barrier function via a monocarboxylate transporter in goat mammary epithelial cells, EXPERIMENTAL CELL RESEARCH, 436(1), 20240301
    Link to Paper Search Results by DOI
  3. Effect of mastitis during early-stage pregnancy on the immunity levels and pregnancy function of goats, ANIMAL REPRODUCTION SCIENCE, 262, 202403
    Link to Paper Search Results by DOI
  4. Effects of topical application of resveratrol on tight junction barrier and antimicrobial compound production in lactating goat mammary glands, VETERINARY RESEARCH, 55(1), 20240216
    Link to Paper Search Results by DOI
  5. Effects of tributyrin supplementation in calf starter on growth, blood parameters and development of rumen and small intestine in Holstein calves fed milk replacers with different fatty acid profile, ANIMAL FEED SCIENCE AND TECHNOLOGY, 308, 202402
    Link to Paper Search Results by DOI
  6. Effect of different inflammation states on the antimicrobial components in milk of goat udders after milking cessation, ANIMAL SCIENCE JOURNAL, 95(1), 202401
    Link to Paper Search Results by DOI
  7. Effects of oral administration of lipopolysaccharide derived from Pantoea agglomerans on innate immunity of mammary glands in dairy goats, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 265, 202311
    Link to Paper Search Results by DOI
  8. Potential effects of gingerol topical application on components of the innate immunity in lactating goat mammary glands, INNATE IMMUNITY, 29(7), 135-149, 202310
    Link to Paper Search Results by DOI
  9. Effect of intramammary lipopolysaccharide challenge after repeated intrauterine infusion of lipopolysaccharide on the inflammation status of goat mammary glands, THERIOGENOLOGY, 212, 104-110, 202312
    Link to Paper Search Results by DOI
  10. Effects of hydrostatic compression on milk production-related signaling pathways in mouse mammary epithelial cells, EXPERIMENTAL CELL RESEARCH, 431(1), 20231001
    Link to Paper Search Results by DOI
  11. Intravaginal injection of Lactobacillus johnsonii may modulates oviductal microbiota and mucosal barrier function of laying hens, POULTRY SCIENCE, 102(8), 202308
    Link to Paper Search Results by DOI
  12. Aging-associated increased nitric oxide production is a potential cause of inferior eggshell quality produced by aged laying hens, THERIOGENOLOGY, 205, 63-72, 20230715
    Link to Paper Search Results by DOI
  13. Menthol application on healthy and inflamed goat udders changes antimicrobial components in milk, ANIMAL SCIENCE JOURNAL, 94(1), e13832, 202301
    Link to Paper Search Results by DOI
  14. Valine Treatment Enhances Antimicrobial Component Production in Mammary Epithelial Cells and the Milk of Lactating Goats Without Influencing the Tight Junction Barrier, JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 28(1), 202312
    Link to Paper Search Results by DOI
  15. Effects of Newcastle Disease/Infectious Bronchitis Vaccine and Feeding Yeast Products on the Innate Immune System in the Proventriculus and Ileum of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 60(1), 2023005, 202301
    Link to Paper Search Results by DOI
  16. Investigating mammary glands of lactating goats for the presence of tertiary lymphoid organs, FRONTIERS IN IMMUNOLOGY, 13, 941333, 20220810
    Link to Paper Search Results by DOI
  17. Effect of 6-n-propyl-2-thiouracil or dexamethasone administration on the responses of antimicrobial components in goat milk to intramammary lipopolysaccharide infusion, ANIMAL SCIENCE JOURNAL, 93(1), 202201
    Link to Paper Search Results by DOI
  18. Effects of ozonized glycerin on inflammation of mammary glands induced by intramammary lipopolysaccharide infusion in goats, ANIMAL SCIENCE JOURNAL, 93(1), 202201
    Link to Paper Search Results by DOI
  19. Effects of Newcastle disease and infectious bronchitis vaccine and yeast products feeding on the innate immune system in the proventriculus and ileum of broiler chicks ., Journal of Poultry Science, 20220000
  20. Differences in antimicrobial components between bacterial culture-positive and -negative bovine clinical mastitis milk., Animal Science Journal, 93, e13771, 20220601
  21. Investigating mammary glands of lactating goats for the presence of tertiary lymphoid organs., Frontiers in Immunology, 13, 941333, 20220810
  22. Effect of repeated intrauterine infusion of lipopolysaccharides on mastitis in goats, THERIOGENOLOGY, 193, 87-92, 202211
    Link to Paper Search Results by DOI
  23. Effect of temporary cessation of milking and estradiol combination on the antimicrobial components in goat milk, RESEARCH IN VETERINARY SCIENCE, 152, 387-394, 20221220
    Link to Paper Search Results by DOI
  24. Differences in antimicrobial components between bacterial culture-positive and culture-negative bovine clinical mastitis milk, ANIMAL SCIENCE JOURNAL, 93(1), 202201
    Link to Paper Search Results by DOI
  25. Adverse Effects of High Temperature On Mammary Alveolar Development In Vitro, JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 27(2), 155-170, 202206
    Link to Paper Search Results by DOI
  26. Sodium Acetate and Sodium Butyrate Differentially Upregulate Antimicrobial Component Production in Mammary Glands of Lactating Goats, JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 27(2), 133-144, 202206
    Link to Paper Search Results by DOI
  27. Modulation of the innate immune system by lipopolysaccharide in the proventriculus of chicks inoculated with or without Newcastle disease and infectious bronchitis vaccine, POULTRY SCIENCE, 101(4), 202204
    Link to Paper Search Results by DOI
  28. Effects of frequent teat stimulation on antimicrobial component production in mammary glands of lactating goats, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 249, 202207
    Link to Paper Search Results by DOI
  29. Sodium acetate and sodium butyrate differentially upregulate antimicrobial component production in mammary glands of lactating goats., Journal of Mammary Gland Biology and Neoplasia, 2022
  30. Effects of frequent teat stimulation on antimicrobial component production in mammary glands of lactating goats., Veterinary Immunology and Immunopathology, 249, 110431, 20220701
  31. Modulation of the innate immune system by lipopolysaccharide in the proventriculus of chicks inoculated with or without Newcastle disease and infectious bronchitis vaccine., Poultry Science, 101(4), 101719, 20220401
  32. Adverse effects of heat stress on mammary alveolar development in vitro., Journal of Mammary Gland Biology and Neoplasia, 2022
  33. Regression tree analysis of the relationship between the concentrations of antimicrobial components and the microbiota of normal milk from dairy cows, JOURNAL OF VETERINARY MEDICAL SCIENCE, 84(3), 310-318, 202203
    Link to Paper Search Results by DOI
  34. Rapid determination of pathogens in mastitic milk of dairy cows using Gram staining, JOURNAL OF VETERINARY MEDICAL SCIENCE, 84(3), 325-329, 202203
    Link to Paper Search Results by DOI
  35. Local Heat Treatment of Goat Udders Influences Innate Immune Functions in Mammary Glands, JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 26(4), 387-397, 202112
    Link to Paper Search Results by DOI
  36. Effect of oral administration of colostrum on inflammation in the udders of dairy cows suffering from mastitis, JOURNAL OF VETERINARY MEDICAL SCIENCE, 84(1), 59-63, 202201
    Link to Paper Search Results by DOI
  37. Slight Disruption in Intestinal Environment by Dextran Sodium Sulfate Reduces Egg Yolk Size Through Disfunction of Ovarian Follicle Growth, FRONTIERS IN PHYSIOLOGY, 11, 20210115
    Link to Paper Search Results by DOI
  38. Immune response during the onset of coliform mastitis in dairy cows vaccinated with STARTVAC (R), ANIMAL SCIENCE JOURNAL, 92(1), 2021
    Link to Paper Search Results by DOI
  39. Association of endometritis and ovarian follicular cyst with mastitis in dairy cows., The Journal of Veterinary Medical Science, 83(2), 338-343, 2021
  40. ★, Effect of temporary cessation of milking on the innate immune components in goat milk., Journal of Dairy Science, 104(9), 10374-10381, 20210901
  41. Effect of temporary cessation of milking on the innate immune components in goat milk, JOURNAL OF DAIRY SCIENCE, 104(9), 10374-10381, 202109
    Link to Paper Search Results by DOI
  42. Concentration patterns of antibacterial factors and immunoglobulin A antibody in foremilk fractions of healthy cows., Animal Science Journal, 91(1), e13372., 2020
  43. Effect of oral administration of colostrum whey to peripartum goat on antimicrobial peptides in postpartum milk., Animal Science Journal, 91(1), e13365, 2020
  44. Seasonal variations in the concentration of antimicrobial components in milk of dairy cows., Animal Science Journal, 91, e13427, 2020
  45. Effects of intrauterine infusion of bacterial lipopolysaccharides on the mammary gland inflammatory response in goats, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 219, 202001
    Link to Paper Search Results by DOI
  46. Effects of Oral Administration of Lactobacillus reuteri on Mucosal Barrier Function in the Digestive Tract of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 57(1), 67-76, 202001
    Link to Paper Search Results by DOI
  47. Intestinal inflammation induced by dextran sodium sulphate causes liver inflammation and lipid metabolism disfunction in laying hens, POULTRY SCIENCE, 99(3), 1663-1677, 202003
    Link to Paper Search Results by DOI
  48. Lactobacillus reuteri Enhances the Mucosal Barrier Function against Heat-killed Salmonella Typhimurium in the Intestine of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 57(2), 148-159, 202004
    Link to Paper Search Results by DOI
  49. Effect of antibiotic treatment on microbial composition and expression of antimicrobial peptides and cytokines in the chick cecum, POULTRY SCIENCE, 99(7), 3385-3392, 202007
    Link to Paper Search Results by DOI
  50. Changes in ionized calcium concentration in the blood of dairy cows with peracute coliform mastitis, JOURNAL OF VETERINARY MEDICAL SCIENCE, 82(4), 457-462, 202004
    Link to Paper Search Results by DOI
  51. Effects of Testicular and Non-Testicular Testosterone on Territorial and Isolation-induced Aggressive Behavior of Male Layer Chicks, JOURNAL OF POULTRY SCIENCE, 57(3), 236-240, 202007
    Link to Paper Search Results by DOI
  52. Effects of Toll-like Receptor Ligands on the Expression of Proinflammatory Cytokines and Avian beta-defensins in Cultured Chick Intestine, JOURNAL OF POULTRY SCIENCE, 57(3), 210-222, 202007
    Link to Paper Search Results by DOI
  53. Translocation of intrauterine-infused bacterial lipopolysaccharides to the mammary gland in dexamethasone-treated goats, Reproduction in Domestic Animals, 2020
  54. Outcome prediction from the first examination in clinical mastitis using ultrasonography in dairy cows., Animal Science Journal, 91(1), e13452, 2020
  55. Effects of Probiotics Lactobacillus reuteri and Clostridium butyricum on the Expression of Toll-like Receptors, Pro- and Anti-inflammatory Cytokines, and Antimicrobial Peptides in Broiler Chick Intestine, JOURNAL OF POULTRY SCIENCE, 57(4), 310-318, 202010
    Link to Paper Search Results by DOI
  56. Effects of oral administration of colostrum whey in peripartum goat on antimicrobial peptides in postpartum milk, ANIMAL SCIENCE JOURNAL, 91(1), 2020
    Link to Paper Search Results by DOI
  57. Concentration patterns of antibacterial factors and immunoglobulin A antibody in foremilk fractions of healthy cows, ANIMAL SCIENCE JOURNAL, 91(1), 2020
    Link to Paper Search Results by DOI
  58. Seasonal variations in the concentration of antimicrobial components in milk of dairy cows, ANIMAL SCIENCE JOURNAL, 91(1), 2020
    Link to Paper Search Results by DOI
  59. Outcome prediction from the first examination in clinical mastitis using ultrasonography in dairy cows, ANIMAL SCIENCE JOURNAL, 91(1), 2020
    Link to Paper Search Results by DOI
  60. Effects of avian infectious bronchitis with Newcastle disease and Marek's disease vaccinations on the expression of toll-like receptors and avian beta-defensins in the kidneys of broiler chicks, POULTRY SCIENCE, 99(12), 7092-7100, 202012
    Link to Paper Search Results by DOI
  61. Translocation of intrauterine-infused bacterial lipopolysaccharides to the mammary gland in dexamethasone-treated goats, REPRODUCTION IN DOMESTIC ANIMALS, 55(12), 1688-1697, 202012
    Link to Paper Search Results by DOI
  62. Short communication: Production of antimicrobial peptide S100A8 in the goat mammary gland and effect of intramammary infusion of lipopolysaccharide on S100A8 concentration in milk, JOURNAL OF DAIRY SCIENCE, 102(5), 4674-4681, 201905
    Link to Paper Search Results by DOI
  63. Age-related modulation of the isthmic and uterine mucosal innate immune defense system in laying hens, POULTRY SCIENCE, 98(7), 3022-3028, 201907
    Link to Paper Search Results by DOI
  64. Effects of the routine multiple vaccinations on the expression of innate immune molecules and induction of histone modification in ovarian cells of layer chicks, POULTRY SCIENCE, 98(10), 5127-5136, 201910
    Link to Paper Search Results by DOI
  65. Blood Testosterone Concentration and Testosterone-induced Aggressive Behavior in Male Layer Chicks: Comparison between Isolated- and Grouped-Raising, JOURNAL OF POULTRY SCIENCE, 56(4), 290-297, 201910
    Link to Paper Search Results by DOI
  66. Effects of Salmonella enteritidis Vaccination on the Expression of Innate Immune Molecules and Histone Modifications in the Follicular Theca of Laying Hens, JOURNAL OF POULTRY SCIENCE, 56(4), 298-307, 201910
    Link to Paper Search Results by DOI
  67. Association between bovine leukemia virus proviral load and severity of clinical mastitis, JOURNAL OF VETERINARY MEDICAL SCIENCE, 81(10), 1431-1437, 201910
    Link to Paper Search Results by DOI
  68. Detection of APAF1 mutation in Holstein cows and mummified foetuses in Japanese dairy herds, REPRODUCTION IN DOMESTIC ANIMALS, 53(1), 137-142, 201802
    Link to Paper Search Results by DOI
  69. Microcystin-leucine-arginine Modulates the Expression Patterns of Proinflammatory Cytokines and an Apoptotic Gene in Chicken Liver, JOURNAL OF POULTRY SCIENCE, 55(1), 70-77, 201801
    Link to Paper Search Results by DOI
  70. Blood ionized calcium levels and acute-phase blood glucose kinetics in goats after intramammary infusion of lipopolysaccharide, JOURNAL OF VETERINARY MEDICAL SCIENCE, 80(2), 242-246, 201802
    Link to Paper Search Results by DOI
  71. Innate antiviral immune response against infectious bronchitis virus and involvement of prostaglandin E2 in the uterine mucosa of laying hens, THERIOGENOLOGY, 110, 122-129, 20180401
    Link to Paper Search Results by DOI
  72. Effects of Interleukin-1 beta and-6 on the Expression of Ion Transporters Involved in Eggshell Mineralization in Cultured Hen Uterine Mucosal Tissue, JOURNAL OF POULTRY SCIENCE, 55(2), 142-149, 201804
    Link to Paper Search Results by DOI
  73. Changes in plasma concentrations of S100A7 and S100A8 in dairy cows during pregnancy, REPRODUCTION IN DOMESTIC ANIMALS, 53(4), 1013-1015, 201808
    Link to Paper Search Results by DOI
  74. Effects of colostrum whey on immune function in the digestive tract of goats, ANIMAL SCIENCE JOURNAL, 89(8), 1152-1160, 201808
    Link to Paper Search Results by DOI
  75. Effect of intramammary lipopolysaccharide infusion on milk pH of uninfused udder in goat, JOURNAL OF VETERINARY MEDICAL SCIENCE, 80(8), 1287-1290, 201808
    Link to Paper Search Results by DOI
  76. Changes in the Expression of Avian beta-defensins (AvBDs) and Proinflammatory Cytokines and Localization of AvBD2 in the Intestine of Broiler Embryos and Chicks during Growth, JOURNAL OF POULTRY SCIENCE, 55(4), 280-287, 201810
    Link to Paper Search Results by DOI
  77. Effects of TLR Ligands on the Expression of Cytokines and Possible Role of NF kappa B in its Process in the Theca of Chicken Follicles, JOURNAL OF POULTRY SCIENCE, 55(4), 288-300, 201810
    Link to Paper Search Results by DOI
  78. Investigation of the binding of goat cathelicidin-7 to lipopolysaccharide and leucocidal suppression of pro-inflammatory cytokines, SMALL RUMINANT RESEARCH, 168, 101-106, 201811
    Link to Paper Search Results by DOI
  79. Expression of pro- and anti-inflammatory cytokines and chemokines during the ovulatory cycle and effects of aging on their expression in the uterine mucosa of laying hens, CYTOKINE, 111, 303-308, 201811
    Link to Paper Search Results by DOI
  80. Investigation of the binding of goat cathelicidin-7 to lipopolysaccharide and leucocidal suppression of pro-inflammatory cytokines., Small Ruminant Research, 168:, 101-106, 2018
  81. Expression and localization of cyclooxygenases in the oviduct of laying hens during the ovulatory cycle, THERIOGENOLOGY, 101, 1-7, 20171001
    Link to Paper Search Results by DOI
  82. Changes in localization and density of CD63-positive exosome-like substances in the hen oviduct with artificial insemination and their effect on sperm viability, THERIOGENOLOGY, 101, 135-143, 20171001
    Link to Paper Search Results by DOI
  83. Effect of nutrient levels during the far-off period on postpartum productivity in dairy cows, ANIMAL SCIENCE JOURNAL, 88(8), 1162-1170, 2017
    Link to Paper Search Results by DOI
  84. Cellular and soluble components decrease the viable pathogen counts in milk from dairy cows with subclinical mastitis, JOURNAL OF VETERINARY MEDICAL SCIENCE, 79(8), 1389-1393, 201712
    Link to Paper Search Results by DOI
  85. Changes in the concentrations of somatic cell counts, lingual antimicrobial peptide and lactoperoxidase activity in milk at periovulatory period in dairy cows, ANIMAL SCIENCE JOURNAL, 88(3), 484-488, 2017
    Link to Paper Search Results by DOI
  86. Effects of inhibitors of transcription factors, nuclear factor-kappa B and activator protein 1, on the expression of proinflammatory cytokines and chemokines induced by stimulation with Toll-like receptor ligands in hen vaginal cells, POULTRY SCIENCE, 96(3), 723-730, 2017
    Link to Paper Search Results by DOI
  87. Control mechanisms for producing antimicrobial factors in ruminant mammary gland, ANIMAL SCIENCE JOURNAL, 88(7), 937-943, 2017
    Link to Paper Search Results by DOI
  88. Effect of steroid hormones on the innate immune response induced by Staphylococcus aureus in the goat mammary gland, REPRODUCTION IN DOMESTIC ANIMALS, 52(4), 579-584, 2017
    Link to Paper Search Results by DOI
  89. Changes in the concentrations of somatic cell counts, lingual antimicrobial peptide and lactoperoxidase activity in milk at periovulatory period in dairy cows., Animal Science Journal, 88(3), 484-488, 20170301
  90. Effect of nutrient levels during the far-off period on postpartum productivity in dairy cows., Animal Science Journal, 2017
  91. The extension of raw milk quality during storage through supplementation of hydrocyanic acid from fresh cassava peel in dairy cattle diet. Songklanakarin Journal of Science and Technology (in press), Songklanakarin Journal of Science and Technology, 2017
  92. The inhibitory effect of sodium thiocyanate and sodium percarbonate rations on microorganism growth in raw milk samples as an effective treatment to extend milk quality during storage., Songklanakarin Journal of Science and Technology, 39(1), 2017
  93. Effects of dietary levels of fresh cassava pulp in dairy cattle diet on productive performance and keeping quality of raw milk. Songklanakarin Journal of Science and Technology (in press), Songklanakarin Journal of Science and Technology, 2017
  94. Microcystin-LR modulates the expression patterns of proinflammatory cytokines and apoptotic gene in the liver of chicken., Journal of Poultry Science, 2017
  95. Cellular and soluble components decrease the viable pathogen counts in milk from dairy cows with subclinical mastitis., The Journal of Veterinary Medical Science, 79(8), 1389-1393, 201708
  96. Melatonin Does Not Affect Progesterone Basal Secretion but Suppresses the Luteinizing Hormone Receptor Expression in Granulosa Cells of the Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(4), 312-318, 201710
    Link to Paper Search Results by DOI
  97. Protective Effect of Melatonin on LPS-stimulated Granulosa Cells in Japanese Quail, JOURNAL OF POULTRY SCIENCE, 54(4), 319-325, 201710
    Link to Paper Search Results by DOI
  98. Modulatory roles of proinflammatory cytokines on the expression of cathelicidins in the lower regions of the oviduct of laying hens, CYTOKINE, 99, 66-72, 201711
    Link to Paper Search Results by DOI
  99. Effects of Probiotics on the Expression of Cathelicidins in Response to Stimulation by Salmonella Minnesota Lipopolysaccharides in the Proventriculus and Cecum of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 53(4), 298-304, 2016
    Link to Paper Search Results by DOI
  100. Goat cathelicidin-2 is secreted by blood leukocytes regardless of lipopolysaccharide stimulation, ANIMAL SCIENCE JOURNAL, 87(3), 423-427, 2016
    Link to Paper Search Results by DOI
  101. Expression of lipases and lipid receptors in sperm storage tubules and possible role of fatty acids in sperm survival in the hen oviduct, THERIOGENOLOGY, 85(7), 1334-1342, 20160415
    Link to Paper Search Results by DOI
  102. Change in viable bacterial count during preservation of milk derived from dairy cows with subclinical mastitis and its relationship with antimicrobial components in milk., The Journal of Veterinary Medical Science, 78(8), 1245-1250, 201608
  103. Expression of lipases and lipid receptors in sperm storage tubules and possible role of fatty acids in sperm survival in the hen oviduct., Theriogenology, 85, 1334-1342, 20160415
  104. Effects of viral-associated molecular patterns on the expression of cathelicidins in the hen vagina., Journal of Poultry Science, 2016
  105. The inhibitory effect of sodium thiocyanate and sodium percarbonate rations on microorganism growth in raw milk samples as an effective treatment to extend milk quality during storage., Songklanakarin Journal of Science and Technology, 39(1), 2016
  106. Effects of inhibitors of transcription factors, nuclear factor-κB and activator protein 1, on the expression of proinflammatory cytokines and chemokines induced by stimulation with Toll-like receptor ligands in hen vaginal cells, Poultry Science, 2016
  107. The effect of estrogen on the early cytotoxic response to IB virus infection in hen oviduct, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 164(42737), 56-66, 20150315
    Link to Paper Search Results by DOI
  108. Dynamics of lingual antimicrobial peptide, lactoferrin concentrations and lactoperoxidase activity in the milk of cows treated for clinical mastitis, ANIMAL SCIENCE JOURNAL, 86(2), 153-158, 201502
    Link to Paper Search Results by DOI
  109. Effects of Probiotics on the Expression and Localization of Avian beta-defensins in the Proventriculus of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 52(1), 57-67, 201501
    Link to Paper Search Results by DOI
  110. Expression of cathelicidins mRNA in the goat mammary gland and effect of the intramammary infusion of lipopolysaccharide on milk cathelicidin-2 concentration, VETERINARY MICROBIOLOGY, 170(42737), 125-134, 20140514
    Link to Paper Search Results by DOI
  111. Effects of different TLR ligands on the expression of proinflammatory cytokines and avian beta-defensins in the uterine and vaginal tissues of laying hens, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 162(42798), 132-141, 20141215
    Link to Paper Search Results by DOI
  112. Innate immune functions in hen reproductive organs, AVIAN BIOLOGY RESEARCH, 7(1), 39-47, 2014
    Link to Paper Search Results by DOI
  113. Effects of calcium salts of medium-chain fatty acids on plasma metabolite and hormone concentrations in early lactating dairy cows, ANIMAL PRODUCTION SCIENCE, 54(10), 1699-1702, 2014
    Link to Paper Search Results by DOI
  114. Messenger RNA expression and immunolocalization of psoriasin in the goat mammary gland and its milk concentration after an intramammary infusion of lipopolysaccharide, VETERINARY JOURNAL, 202(1), 89-93, 2014
    Link to Paper Search Results by DOI
  115. Effects of avian infectious bronchitis virus antigen on eggshell formation and immunoreaction in hen oviduct, THERIOGENOLOGY, 81(8), 1129-1138, 2014
    Link to Paper Search Results by DOI
  116. Toll-like receptor signaling for the induction of mucin expression by lipopolysaccharide in the hen vagina, POULTRY SCIENCE, 93(3), 673-679, 2014
    Link to Paper Search Results by DOI
  117. Relationship between the somatic cell count in milk and reproductive function in peripartum dairy cows, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 60(6), 433-437, 2014
  118. Relationship between concentration of lingual antimicrobial peptide and somatic cell count in milk of dairy cows, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 153(42798), 298-301, 20130615
    Link to Paper Search Results by DOI
  119. Expression of tight junction molecule claudins" in the lower oviductal segments and their changes with egg-laying phase and gonadal steroid stimulation in hens", THERIOGENOLOGY, 79(2), 211-218, 20130115
    Link to Paper Search Results by DOI
  120. Comparison of cadherin and integrin localization in bovine cystic and healthy follicles, ANIMAL SCIENCE JOURNAL, 84(4), 303-309, 2013
    Link to Paper Search Results by DOI
  121. Dectin-1 gene polymorphism is associated with susceptibility to nonspecific digestive disorders and cytokine expression in rabbits, JOURNAL OF ANIMAL SCIENCE, 91(9), 4051-4059, 2013
    Link to Paper Search Results by DOI
  122. Lingual antimicrobial peptide and lactoferrin concentrations and lactoperoxidase activity in bovine colostrum are associated with subsequent somatic cell count, ANIMAL SCIENCE JOURNAL, 84(11), 751-756, 2013
    Link to Paper Search Results by DOI
  123. Induction of avian beta-defensins by CpG oligodeoxynucleotides and proinflammatory cytokines in hen vaginal cells in vitro, REPRODUCTION, 145(6), 621-631, 2013
    Link to Paper Search Results by DOI
  124. Effects of Probiotics on the Localization of T Cell Subsets in the Intestine of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 50(3), 275-281, 2013
    Link to Paper Search Results by DOI
  125. Effects of Lipopolysaccharide on the Recruitment of T Cells in the Seminal Tract of Roosters, JOURNAL OF POULTRY SCIENCE, 50(1), 68-73, 2013
    Link to Paper Search Results by DOI
  126. Effects of Repeated Lipopolysaccharide Stimulation on the Development of Antigen-presenting Cells and T Cells Pool in Hen Vagina, JOURNAL OF POULTRY SCIENCE, 50(1), 83-89, 2013
    Link to Paper Search Results by DOI
  127. Induction of mucin expression by estrogen and lipopolysaccharide in the lower oviductal segments in hens, POULTRY SCIENCE, 92(12), 3205-3213, 2013
    Link to Paper Search Results by DOI
  128. Relationship between concentration of lingual antimicrobial peptide and somatic cell count in milk of dairy cows, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 153(3-4), 298-301, 2013
  129. Effects of Probiotics on the Localization of T Cell Subsets in the Intestine of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 50(3), 275-281, 2013
  130. Expression of Toll-like receptors and effects of lipopolysaccharide on the expression of proinflammatory cytokines and chemokine in the testis and epididymis of roosters, POULTRY SCIENCE, 91(8), 1997-2003, 2012
    Link to Paper Search Results by DOI
  131. Differences in the mucosal surface barrier formed by mucin in the lower oviductal segments between laying and molting hens, POULTRY SCIENCE, 91(5), 1173-1178, 20120501
    Link to Paper Search Results by DOI
  132. Differential immunolocalization between lingual antimicrobial peptide and lactoferrin in mammary gland of dairy cows, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 145(42737), 499-504, 20120115
    Link to Paper Search Results by DOI
  133. Effect of enterotoxigenic Escherichia coli vaccine on innate immune function of bovine mammary gland infused with lipopolysaccharide, JOURNAL OF DAIRY SCIENCE, 95(9), 5067-5074, 2012
    Link to Paper Search Results by DOI
  134. Effects of lipopolysaccharide and interleukins on the expression of avian beta-defensins in hen ovarian follicular tissue, POULTRY SCIENCE, 91(11), 2877-2884, 2012
    Link to Paper Search Results by DOI
  135. Effects of lipopolysaccharide on the expression of proinflammatory cytokines and chemokines and influx of leukocytes in the hen ovary, POULTRY SCIENCE, 90(9), 2054-2062, 20110901
    Link to Paper Search Results by DOI
  136. Effects of lipopolysaccharide on the expression of proinflammatory cytokines and chemokines and the subsequent recruitment of immunocompetent cells in the oviduct of laying and molting hens, POULTRY SCIENCE, 90(10), 2332-2341, 20111001
    Link to Paper Search Results by DOI
  137. Differential localization of lingual antimicrobial peptide in the digestive tract mucosal epithelium of calves, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 142(42737), 87-94, 20110715
    Link to Paper Search Results by DOI
  138. Expression of Toll-like receptors and avian beta-defensins and their changes in response to bacterial components in chicken sperm, POULTRY SCIENCE, 90(2), 417-425, 20110201
    Link to Paper Search Results by DOI
  139. Detection of Avian Beta-defensins mRNA and Proteins in Male Reproductive Organs in Chicken, JOURNAL OF POULTRY SCIENCE, 48(4), 275-280, 2011
    Link to Paper Search Results by DOI
  140. Changes in the Density of Immunoreactive Avian beta-Defensin-3 and-11 in the Hen Uterus in Response to Lipopolysaccharide Inoculation, JOURNAL OF POULTRY SCIENCE, 48(1), 73-77, 2011
    Link to Paper Search Results by DOI
  141. Lactoperoxidase activity in milk is correlated with somatic cell count in dairy cows, JOURNAL OF DAIRY SCIENCE, 94(8), 3868-3874, 2011
    Link to Paper Search Results by DOI
  142. Follicular Persistence Induced by Adrenocorticotropic Hormone Administration in Goats, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 57(2), 212-216, 2011
    Link to Paper Search Results by DOI
  143. Analysis of Changes in the Expression of Transforming Growth Factor-beta s in the Utero-vaginal Junction of Hen Oviduct in Response to Sperm Concerning Their Significance in Sperm Survivability, JOURNAL OF POULTRY SCIENCE, 47(4), 326-332, 2010
    Link to Paper Search Results by DOI
  144. Effects of Feeding Probiotics on the Localization of Cells Containing Immunoreactive Interleukin-6 in the Intestine of Broiler Chicks, JOURNAL OF POULTRY SCIENCE, 47(3), 250-255, 2010
    Link to Paper Search Results by DOI
  145. Changes in the Localization of Immunoreactive Avian Beta-Defensin-8,-10 and-12 in Hen Ovarian Follicles during Follicular Growth, JOURNAL OF POULTRY SCIENCE, 47(1), 77-84, 2010
    Link to Paper Search Results by DOI
  146. Expression of Toll-like receptors (TLRs) and TLR4 response to lipopolysaccharide in hen oviduct, VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 127(42798), 259-268, 20090215
    Link to Paper Search Results by DOI
  147. Co-transfer of parthenogenotes and single porcine embryos leads to full-term development of the embryos, ANIMAL REPRODUCTION SCIENCE, 112(42737), 8-21, 2009
    Link to Paper Search Results by DOI
  148. Changes in the expression of interleukin-1 beta and lipopolysaccharide-induced TNF factor in the oviduct of laying hens in response to artificial insemination, REPRODUCTION, 137(3), 527-536, 2009
    Link to Paper Search Results by DOI
  149. Existence of functional lingual antimicrobial peptide in bovine milk, JOURNAL OF DAIRY SCIENCE, 92(6), 2691-2695, 2009
    Link to Paper Search Results by DOI
  150. Identification of Ghrelin in Fertilized Eggs of Chicken, JOURNAL OF POULTRY SCIENCE, 46(3), 257-259, 2009
    Link to Paper Search Results by DOI
  151. Intramammary challenge of lipopolysaccharide stimulates secretion of lingual antimicrobial peptide into milk of dairy cows, JOURNAL OF DAIRY SCIENCE, 92(12), 6046-6051, 2009
    Link to Paper Search Results by DOI
  152. Immunolocalization of avian beta-defensins in the hen oviduct and their changes in the uterus during eggshell formation, REPRODUCTION, 138(6), 971-978, 2009
    Link to Paper Search Results by DOI
  153. ★, Existence of Functional Lingual Antimicrobial Peptide (LAP) in Bovine Milk, Journal of Dairy Science, 92(6), 2691-2695, 20090601
  154. Immunolocalization of lingual antimicrobial peptide (LAP) in the bovine mammary gland, ANIMAL SCIENCE JOURNAL, 80(4), 446-450, 2009
    Link to Paper Search Results by DOI
  155. Immunolocalization of lingual antimicrobial peptide (LAP) in the bovine mammary gland, ANIMAL SCIENCE JOURNAL, 80(4), 446-450, 2009
  156. Expression of avian beta-defensins in the oviduct and effects of lipopolysaccharide on their expression in the vagina of hens, POULTRY SCIENCE, 87(5), 979-984, 2008
    Link to Paper Search Results by DOI
  157. Poultry production profile and expected future projection in Bangladesh, WORLDS POULTRY SCIENCE JOURNAL, 64(1), 99-117, 2008
    Link to Paper Search Results by DOI
  158. Expression of vascular endothelial growth factor receptors in bovine cystic follicles, REPRODUCTION IN DOMESTIC ANIMALS, 43(3), 267-271, 2008
    Link to Paper Search Results by DOI
  159. Changes in the localization of immunoreactive avian beta-defensin-12 in ovarian follicles during follicular growth and in response to lipopolysaccharide, JOURNAL OF POULTRY SCIENCE, 45(3), 210-214, 2008
    Link to Paper Search Results by DOI
  160. Mechanism of Prolonged Sperm Storage and Sperm Survivability in Hen Oviduct: A Review, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 60(6), 477-481, 2008
    Link to Paper Search Results by DOI
  161. Expression of Avian beta-Defensin 3, an Antimicrobial Peptide, by Sperm in the Male Reproductive Organs and Oviduct in Chickens: An Immunohistochemical Study, POULTRY SCIENCE, 87(12), 2653-2659, 2008
    Link to Paper Search Results by DOI
  162. Ovarian Cyclicity and Reproductive Performance of Holstein Cows Carrying the Mutation of Complex Vertebral Malformation in Japan., Reproduction in Domestic Animals, IN PRESS, 20080101
  163. Changes in fecal progestagen profile after excretion in miniature pigs, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 53(5), 1107-1112, 2007
    Link to Paper Search Results by DOI
  164. Deficient proliferation and apoptosis in the granulosa and theca interna cells of the bovine cystic follicle, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 53(5), 1119-1124, 2007
    Link to Paper Search Results by DOI
  165. Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus), REPRODUCTION, 133(1), 127-133, 2007
    Link to Paper Search Results by DOI
  166. Follicular cysts in dairy cows, ANIMAL SCIENCE JOURNAL, 78(1), 1-6, 2007
    Link to Paper Search Results by DOI
  167. Fecal progestagen and estrone during pregnancy in a giraffe: A case report, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 53(1), 159-164, 2007
    Link to Paper Search Results by DOI
  168. Changes in the expression of Toll-like receptor mRNAs during follicular growth and in response to lipopolysaccharide in the ovarian follicles of laying hens, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 53(6), 1227-1235, 2007
    Link to Paper Search Results by DOI
  169. Involvement of plasma progesterone, Oestradiol-17 beta and cortisol in ovulatory response to gonadotropin-releasing hormone in dairy cows with cystic follicles, REPRODUCTION IN DOMESTIC ANIMALS, 42(4), 370-375, 2007
    Link to Paper Search Results by DOI
  170. Preparation and Application for Immunocytochemistry of Antibody to Gallinacin-3, an Antimicrobial Peptide, in Chicken., Journal of Poultry Science, 44(4), 433-438, 20071001
  171. Changes in the mRNA expressions of sperm Transforming Growth Factor beta-isoforms and their receptors with reference to fertility during in vitro storage of fowl semen., Journal of Poultry Science, 44(2), 189-197, 20070401
  172. Studies of the role of steroid hormone in the regulation of oocyte maturation in cattle, REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 4, 20060203
    Link to Paper Search Results by DOI
  173. Expression of transforming growth factor-beta isoforms and their receptors in utero-vaginal junction of hen oviduct in presence or absence of resident sperm with reference to sperm storage, REPRODUCTION, 132(5), 781-790, 2006
    Link to Paper Search Results by DOI
  174. Effects of age and gonadal steroids on the localization of antigen presenting cells in the epididymis of the male chicken, gallus domesticus, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 52(3), 363-371, 2006
    Link to Paper Search Results by DOI
  175. Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 52(2), 211-218, 2006
    Link to Paper Search Results by DOI
  176. Enzyme Histochemical Localization of Peroxidase Activity in the Oviduct of Immature, Laying and Non-laying Hens. (),, Journal of Poultry Science, 43(4), 401-407, 20061001
  177. Measurement of fecal progesterone concentration in miniature pig using the direct EIA method, 3, 27-29, 20060301
  178. Studies on substantially increased proteins in follicular fluid of bovine ovarian follicular cysts using 2-D PAGE and MALDI-TOF MS, REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 3, 20050608
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  179. Expression of gap junction protein connexin 43 during follicular atresia in the ovary of swamp buffaloes, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 51(5), 675-681, 2005
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  180. Microvascular distribution and vascular endothelial growth factor expression in bovine cystic follicles, DOMESTIC ANIMAL ENDOCRINOLOGY, 29(4), 634-645, 2005
    Link to Paper Search Results by DOI
  181. Enzyme immunoassay of progesterone in the feces from beef cattle to monitor the ovarian cycle, ANIMAL REPRODUCTION SCIENCE, 87(42737), 1-10, 2005
    Link to Paper Search Results by DOI
  182. Gonadotropin-induced Delta 14-reductase and Delta 7-reductase gene expression in cumulus cells during meiotic resumption of porcine oocytes, ENDOCRINOLOGY, 146(1), 186-194, 2005
    Link to Paper Search Results by DOI
  183. Pregnancy diagnosis based on the fecal progesterone concentration in beef and dairy heifers and beef cows, ANIMAL REPRODUCTION SCIENCE, 90(42798), 211-218, 2005
    Link to Paper Search Results by DOI
  184. Immunolocalization of von Willebrand factor and vascular endothelial growth factor during follicular atresia in the swamp buffalo ovary, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 51(4), 419-426, 2005
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  185. Apoptosis in the antral follicles of swamp buffalo and cattle ovary: TUNEL and caspase-3 histochemistry, REPRODUCTION IN DOMESTIC ANIMALS, 40(2), 111-116, 2005
    Link to Paper Search Results by DOI
  186. Expressions of antimicrobial peptide gallinacin-1,-2 and -3 mRNAs in the oviduct of laying hens., Journal of Poultry Science, 42(4), 337-345, 20051025
  187. Direct enzyme immunoassay of fecal estrone derivatives in dairy cows. :, Animal Science Journal, 76(3), 203-207, 20050701
  188. Characteristics of cryopreserved spermatozoa from a holstein friesian bull thawed at different temperature., Journal of Internatinal Development and Cooperation, 12(1), 107-110, 20050401
  189. Pregnancy diagnosis in miniature pig by direct ELISA of oestrone derivatives in faeces, REPRODUCTION IN DOMESTIC ANIMALS, 39(1), 48-51, 2004
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  190. Cell proliferation in the atretic follicles of buffalo and cattle ovary, REPRODUCTION IN DOMESTIC ANIMALS, 39(6), 405-409, 2004
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  191. Determination of estrous cycle and pregnancy diagnosis in miniature pig by measuring plasma progesterone concentrations., 1, 25-28, 20040301
  192. Atresia ani with diphallus and separate scrota in a calf: a case report, THERIOGENOLOGY, 61(42924), 1205-1213, 2004
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  193. Changes in the thecal vasculature during follicular atresia in the ovary of swamp buffalo, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 50(3), 315-321, 2004
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  194. Incidence of silent ovulation in dairy cows during post partum period, DEUTSCHE TIERARZTLICHE WOCHENSCHRIFT, 111(1), 35-38, 2004
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  195. Phosphatidylinositol 3-kinase in cumulus cells is responsible for both suppression of spontaneous maturation and induction of gonadotropin-stimulated maturation of porcine oocytes, JOURNAL OF ENDOCRINOLOGY, 179(1), 25-34, 2003
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  196. Distribution of cytochrome p450-side chain cleavage in the theca interna layers of bovine small antral and cystic follicles, REPRODUCTION IN DOMESTIC ANIMALS, 38(5), 405-409, 2003
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  197. Plasma concentration of estrone sulfate during pregnancy in different breeds of Japanese beef cattle, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 49(5), 369-374, 2003
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  198. Effects of body condition score in cows peripartum on the onset of postpartum ovarian cyclicity and conception rates after ovulation synchronization/fixed-time artificial insemination, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 49(5), 381-388, 2003
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  199. Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase in the granulosa and theca interna layers of bovine cystic follicles, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 49(3), 227-233, 2003
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  200. Luteinizing hormone receptor formation in cumulus cells surrounding porcine oocytes and its role during meiotic maturation of porcine oocytes, BIOLOGY OF REPRODUCTION, 68(4), 1142-1149, 2003
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  201. Effects of estrone sulfate injection on reproductive functions in male Japanese quail., Journal of Poultry Science, 40, 243-247, 20031001
  202. Direct enzyme immunoassay of progesterone in bovine plasma., Anim Sci J, 74, 369-373, 20031001
  203. Direct enzyme immunoassay of estrone sulfate in the plasma of cattle, J Reprod Dev, 48(1), 75-78, 20020201
  204. Direct enzyme immunoassay of estrone sulfate in the plasma of cattle, JOURNAL OF REPRODUCTION AND DEVELOPMENT, 48(1), 75-78, 2002
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  205. Survival of boar spermatozoa frozen in diluents of varying osmolality, THERIOGENOLOGY, 56(3), 447-458, 20010801
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  206. Changes in the Localization of Immunoreactive von Willebrand Factor in Microvascular Network of Bovine Ovarian Follicles during Atresia, Animal Science Journal, 72(6), 473-482, 20011101
  207. An in situ hybridization study of the effects of artificial insemination on the localization of cells expressing MHC class II mRNA in the chicken oviduct, Reproduction, 122(4), 581‐586, 20011001
  208. An in situ hybridization study of the effects of artificial insemination on the localization of cells expressing MHC class II mRNA in the chicken oviduct, REPRODUCTION, 122(4), 581-586, 2001
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  209. Effect of the Factor inhibiting germinal vesicle breakdown on the disruption of gap junctions and cumulus expansion of pig cumulus-oocyte complexes cultured in vitro, REPRODUCTION, 121(2), 249-257, 2001
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  210. Immunocytochemical study of cell proliferation in the cystic ovarian follicles in cows, THERIOGENOLOGY, 54(7), 1159-1169, 20001015
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  211. Localization of apoptotic cells in the cystic ovarian follicles of cows: A DNA-end labeling histochemical study, THERIOGENOLOGY, 53(4), 897-904, 20000301
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  212. Involvement of meiotic resumption in the disruption of gap junctions between cumulus cells attached to pig oocytes., Journal of Reproduction and Fertility, 113, 167-172, 1998
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Invited Lecture, Oral Presentation, Poster Presentation

  1. Effect of milking time on yield, composition and antimicrobial component in milk of lactating goats., Zi-Long Liang, Naoki Suzuki, Takahiro Nii, Naoki Isobe, 2023/09/19, Without Invitation, English
  2. Leukocytes function in goat milk after intrauterine infusion of lipopolysaccharide., Jaisue Jirapat, Nii Takahiro, Suzuki Naoki, Isobe Naoki., 2023/09/19, Without Invitation, English
  3. Decrease in viable bacterial counts by leukocytes during preservation of milk from mastitic dairy cows., Naoki Isobe, Keiichi Hisaeda, Tomoko Koshiishi, Naoki Suzuki, 10th Internatinal seminorof tropical Animal Production (ISTAP), 2023/11/08, Without Invitation, English, Yogyakarta, Indonesia
  4. Continued Intrauterine Lipopolysaccharide Infusion: Its Effect on Goat Mastitis.(Nov. 8-9, Yogyakarta, Indonesia), Jaisue Jirapat, Nii Takahiro, Suzuki Naoki, Isobe Naoki., 10th Internatinal seminorof tropical Animal Production (ISTAP), 2023/11/08, Without Invitation, English, Yogyakarta, Indonesia
  5. Suppression of neutrophil phagocytosis in mastitic milk., 2022/09/15, Without Invitation, English
  6. Influence of sodium acetate and sodium butyrate on tight junction barrier and antimicrobial component production in goat mammary glands., Tsugami Y, Nii T, Yoshimura Y, Isobe N, 19th AAAP Congress., 2022/08/23, Without Invitation, English, AAAP, Jeju, Korea
  7. Effect of Continual Intrauterine Infusion of Lipopolysaccharide on Mastitis in Goats., Jaisue J, Nii T, Tsugami Y, Isobe N, 19th AAAP Congress., 2022/08/24, Without Invitation, English, AAAP, Jeju, Korea
  8. Innate immunity of mammary gland and recent developments in treatments for mastitis, Naoki Isobe, 75th Annual Scientific Sessions 2023, 2023/09/15, With Invitation, English, 75th Annual Scientific Sessions 2023, Sri Lanka
  9. Cause of NG milk, Naoki Isobe, Japan Dairy Farming Youth Research Federation Kansai Council, 2023/07/06, With Invitation, Japanese, Japan Dairy Farming Youth Research Federation Kansai Council, Himeji Labor Hall
  10. cause of no growth milk, Naoki Isobe, NOSAI Hiroshima Technical Seminor, 2023/03/10, With Invitation, Japanese
  11. innate immunity in dairy cows, Naoki Isobe, Chiba prefecture technical seminor, 2022/12/09, With Invitation, Japanese, Shiyokai, NOSAI chiba
  12. No growth milk: cause and solution, Naoki Isobe, 7th Hiroshima University Dairy Seminor, 2022/11/16, With Invitation, Japanese, RCAS, Kurara, Higashi-Hiroshima center
  13. Antimicrobial components in mastitis, Naoki Isobe, 20220821, 2022/08/21, With Invitation, Japanese, Bovine Mastitis Rresearch, Aenoac
  14. Effect of Repeated Intrauterine Infusion of Lipopolysaccharide on Mastitis in Goat., Jirapat Jaisue, Takahiro Nii, Yukinori Yoshimura, Yusaku Tsugami, Naoki Isobe, Jirapat Jaisue, Takahiro Nii, Yukinori Yoshimura, Yusaku Tsugami, Naoki Isobe, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  15. Effects of medium-chain fatty acids supplementation on immunoglobulin level in dairy calves., Shimizu M,, Sugino T, Isobe N, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia,
  16. Changes in innate immune components in goat mammary gland applied with menthol., Ruri Ohno, Yusaku Tsugami, Takahiro Nii, Yukinori Yoshimura, Ken Kobayashi, Naoki Isobe, Ruri Ohno, Yusaku Tsugami, Takahiro Nii, Yukinori Yoshimura, Ken Kobayashi, Naoki Isobe, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  17. Anti-inflammatory effect of ozone infused into mammary gland of goat., Masato Hirano, Takahiro Nii, Yukinori Yoshimura, Gotaro Shiota, Naoki Isobe, Masato Hirano, Takahiro Nii, Yukinori Yoshimura, Gotaro Shiota, Naoki Isobe, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  18. Effect of oral administration of nucleotide on immunoglobulin production in goat., Kohei Murata, Takahiro Nii, Yukinori Yoshimura, Kazutoshi Ueno, Naoki Isobe, Kohei Murata, Takahiro Nii, Yukinori Yoshimura, Kazutoshi Ueno, Naoki Isobe, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  19. Effects of intra-vaginal administration of lactic acid bacteria on the oviductal mucosal barrier function of the laying hens., Taro Shinkoda, Naoki Isobe, Yukinori Yoshimura, Takahiro Nii, Taro Shinkoda, Naoki Isobe, Yukinori Yoshimura, Takahiro Nii, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  20. Effect of local heat treatment on innate immune function in goat mammary glands., Yusaku Tsugami, Yuki Ishiba, Naoki Suzuki, Takahiro Nii, Yukinori Yoshimura, Ken Kobayashi, and Naoki Isobe, Yusaku Tsugami, Yuki Ishiba, Naoki Suzuki, Takahiro Nii, Yukinori Yoshimura, Ken Kobayashi, and Naoki Isobe, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, Gadjah Mada University, Gadjah Mada University, Indonesia
  21. Effects of Partially Hydrolyzed Guar Gum Feeding on Intestinal Environment of Laying Hens., Takahiro Nii, Naoki Isobe, Yukinori Yoshimura, Takahiro Nii, Naoki Isobe, Yukinori Yoshimura, The 9th International Seminar on Tropical Animal Production (ISTAP), 2021/09/21, Without Invitation, English, University of Gadjah Mada, Indonesia
  22. Relationship between milk Ig level and inflammation status induced by intramammary infusion of E.coli, Shimizu M,Nii T,Yoshimura Y,Isobe N, Shimizu M,Nii T,Yoshimura Y,Isobe N, Animal Science Congress, 2021/09/14, Without Invitation, Japanese, Japanese Animal Science Association
  23. Lipopolysaccharides infusion into the uterus causes inflammation in the mammary gland, Fika Yuliza Purba1, Takahiro Nii, Yukinori Yoshimura, Naoki Isobe, Fika Yuliza Purba1, Takahiro Nii, Yukinori Yoshimura, Naoki Isobe, 2021/03/28, Without Invitation, Japanese
  24. Antimicrobial components for the local defense in ruminant mammary gland, ISOBE Naoki, The 3rd International Conference of Animal Science and Technology (ICAST 3), 2020/11, With Invitation, English, Hasanuddin University, Hasanuddin University
  25. Inflammatory responses in the mammary gland after intrauterine infusion of lipopolysaccharide in dexamethasone-treated goats, Purba FY, Nii T, Yoshimura Y, Isobe N, Purba FY, Nii T, Yoshimura Y, Isobe N, 1st International Veterinay Science Virtual Conference (ICVS), 2020/10/04, Without Invitation, English, Hasanuddin University, Hasanuddin University
  26. Effect of oral administration of colostrum on the antimicrobial peptides concentration in goat milk., Isobe N, Kubo K, Ueno K, Nii T, Yoshimura Y, The 8th International Seminar on Tropical Animal Production (ISTAP)　, 2019/09/23, Without Invitation, English, The 8th International Seminar on Tropical Animal Production (ISTAP)　, Yogyakarta, Indonesia
  27. Different concentration of antimicrobial components in bovine milk infected with different pathogens, Isobe N, Kawai K, Shinozuka Y, Purba YF, Nii T, Yoshimura Y, The 30th World Buiatrics Congress, 2018/08/29, Without Invitation, English, World Buiatrics, Sapporo Convention Center, Sapporo
  28. Effect of mastitis on the reproductive functions in pregnant goat., Isobe N, Kodama N, Nii T, Yoshimura Y, 18th AAAP Congress., 2018/08/01, Without Invitation, English, Asian Austrasian Animal Production, Sarawak, Malaysia
  29. Effect of tentative cessation of milking for 3 days on innate immune components in goat milk, Naoki Isobe, Jo Ueda, Yukinori Yoshimura, 2018 Annual Meeting of the American Dairy Science Association, 2018/07/25, Without Invitation, English, American Dairy Science Association, Knoxville,Tennessee, USA
  30. innate immune function for the prevention of mastitis, Naoki Isobe, 2017/10/06, With Invitation, Japanese
  31. mastitis and innate immunity, Naoki Isobe, 2017/05/27, With Invitation, Japanese
  32. Cessation of milking and antimicrobial peptides, Naoki Isobe, Bovine Mastitis Research, 2017/04/15, With Invitation, Japanese
  33. changes in vial bacterial count in mastitic milk and its reason, Naoki Isobe, 2017/03/07, With Invitation, Japanese
  34. Mastitis and innate immunity, Naoki Isobe, 2016/11/05, With Invitation, Japanese, Rakuno Gakuen University
  35. Effect of steroid hormone on innate immune response induced by Staphylococcus aureus in mammary gland of goat．, Isobe N, Kuwahara K, Yoshimura Y, The 17th AAAP Animal Science Congress, 2016/08/22, Without Invitation, English, AAAP, Kyusyusangyo University
  36. Changes in pathogen number during preservation of milk derived from mastitic dairy cows., Isobe N, Hisaeda K, Koshiishi T, Watanabe M, Miyake H, Yoshimura Y, The 6th International Seminar on Tropical Animal Production (ISTAP), 2015/10/20, Without Invitation, English, Yogyakarta, Indonesia
  37. Innate immunity in mammary gland, Naoki Isobe, 2015/02/15, With Invitation, Japanese
  38. Association of reproductive performance with somatic cell count in milk of dairy cows., Isobe N, Iwamoto C, Yoshimura Y, The 16th AAAP Animal Science Congress, 2014/10/10, Without Invitation, English, Yogyakarta, Indonesia
  39. Antimicrobial factors in milk, Naoki Isobe, 2014/08/22, With Invitation, Japanese, NOSAI

Awards

  1. 2023/11/18, English Presentation Award, 日本畜産学会, Effect of milking time on yield, composition and antimicrobial component in milk of lactating goats.
  2. 2023/09/19, English Presentation Award, 日本畜産学会, Leukocytes function in goat milk after intrauterine infusion of lipopolysaccharide.
  3. 2024, Top Cited Article 2022-2023, Wiley, Differences in antimicrobial components between bacterial culture-positive and -negative bovine clinical mastitis milk.
  4. 2022/08/26, Outstanding Student competition Award, President of AAAP, Effect of Continual Intrauterine Infusion of Lipopolysaccharide on Mastitis in Goats
  5. 2021/09/28, English Presentation Award, Japan Animal Science Association, Relationship between milk Ig level and inflammation status induced by intramammary infusion of E.coli
  6. 2021/03/28, Best presenter, Japan Animal Science Association, Lipopolysaccharides infusion into the uterus causes inflammation in the mammary gland
  7. 2019/09/24, Best oral presenter, Dean of Faculty of Animal Science, Universitas Gadjah Mada, Chairman of Organizing Committee, Effect of low milking frequency on the concentration of antimicrobial peptides in goat milk
  8. 2018/03/28, The 2018 Award for Excellence in Reviewing for Animal Science Journal in 2017, 公益社団法人日本畜産学会編集委員長
  9. 2015/03/28, Animal Science Journal Reviewers Award (Reviewers賞), 日本畜産学会編集委員会

Patented

  1. Patent, 7244029, 2023/03/13
  2. Patent, 11026961, 2021/06/08
  3. Patent, 7038364, 2022/03/10

External Funds

Acceptance Results of Competitive Funds

  1. 2024, 2028
  2. 2024, 2026
  3. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  4. 2021, 2024
  5. 2019, 2021
  6. 2019/04, 2021/03
  7. Prevention of calf diarrhea by utilizing antimicrobial peptide in colostrum, 2017, 2017
  8. KAKENHI, 2015, 2017
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  9. 2015
  10. KAKENHI, 2012, 2014
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  11. 2012
  12. 2011, 2013
  13. KAKENHI, Studies on the mechanism of antimicrobial peptide synthesis for a strategy to enhance the innate immunity in hen oviduct, 2009, 2012
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  14. KAKENHI, Development of Fertility Improvement Program in Dairy Cows based on Postpartum Reproductive Monitoring System, 2008, 2010
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  15. KAKENHI, 2006, 2008
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  16. KAKENHI, 2006, 2008
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  17. KAKENHI, 2004, 2005
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  18. KAKENHI, Environmental pollution by sex steroids and assessment for their effects on animals and plants, 2003, 2004
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  19. KAKENHI, 2000, 2000
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  20. KAKENHI, Studies on potential of domestic ruminants in tropical Asia, 2000, 2003
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  21. KAKENHI, Feto-Placental Function during Pregnancy and the Calf Viability, 2000, 2001
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  22. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2018/12/01, 2019/03/31
  23. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2018, 2020
  24. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2019/04/01, 2021/03/31

Social Activities

History as Peer Reviews of Academic Papers

  1. 2023, Animal Science Journal, Editor, 5
  2. 2021, Animal Science Journal, Editor
  3. 2020, Bioscience, Biotechnology, and Biochemistry, Others, 1
  4. 2020, Animal Science Journal, Editor, 5
  5. 2014, Animal Science Journal, Others
  6. 2014, Journal of Reproduction and Development
  7. 2014, Domestic Animal Endocrinology
  8. 2014, BMC Veterinary
  9. 2014, Current Protein & Peptide Science
  10. Veterinary Research