ATSUSI OONO
Last Updated :2025/02/04
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Medical), Associate Professor or Lecturer
- E-mail
- atsushi-o
hiroshima-u.ac.jp
Basic Information
Academic Degrees
Educational Activity
- [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine
Research Fields
- Medicine,dentistry, and pharmacy;Clinical internal medicine;Gastroenterology
Research Keywords
- Liver cancer, Viral hepatitis
Affiliated Academic Societies
- the Japan Society of Hepatology
- the Japanese Society of Internal Medicine
- the Japanese Society of Gastroenterology
- Japan Gastroenterological Endoscopy Society
Educational Activity
Course in Charge
- 2024, Undergraduate Education, Year, Clinical diagnosis and treatment I
- 2024, Undergraduate Education, Intensive, Introduction to clinical clerkship
- 2024, Undergraduate Education, Intensive, Practice of Medicine I
- 2024, Undergraduate Education, Intensive, Practice of Medicine II
- 2024, Undergraduate Education, First Semester, Internal Medicine I
Research Activities
Academic Papers
- Association of Hepatobiliary Phase of Gadoxetic-Acid-Enhanced MRI Imaging with Immune Microenvironment and Response to Atezolizumab Plus Bevacizumab Treatment, CANCERS, 15(17), 202309
- Sodium-glucose cotransporter-2 inhibitors improve FibroScan-aspartate aminotransferase scores in patients with nonalcoholic fatty liver disease complicated by type 2 diabetes, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 35(9), 989-996, 202309
- Successful Lenvatinib Re-challenge following Atezolizumab Plus Bevacizumab Combination Therapy Failure for Unresectable Hepatocellular Carcinoma, INTERNAL MEDICINE, 62(12), 1771-1774, 2023
- Impact and usefulness of the transition to the new MAFLD classification for non-B, non-C HCC: a retrospective cohort study, BMC GASTROENTEROLOGY, 23(1), 20230628
- Evaluation of Response to Atezolizumab Plus Bevacizumab in Patients with Advanced Hepatocellular Carcinoma Using the Combination of Response Evaluation Criteria in Solid Tumors and Alpha-Fetoprotein, CANCERS, 15(8), 202304
- Hepatitis B Virus (HBV) Upregulates TRAIL-R3 Expression in Hepatocytes Resulting in Escape From Both Cell Apoptosis and Suppression of HBV Replication by TRAIL, JOURNAL OF INFECTIOUS DISEASES, 227(5), 686-695, 20230301
- Effectiveness of Repeated Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma-Consideration of the Locations of Target Lesions, CANCERS, 15(3), 202302
- Evaluation of atezolizumab plus bevacizumab combination therapy for hepatocellular carcinoma using contrast-enhanced ultrasonography, JOURNAL OF MEDICAL ULTRASONICS, 50(1), 57-62, 202301
- Low-Dose Alcohol-Induced Inhibition of Mouse Orthotopically Transplanted Tumors Is Associated with T-Cell Response, PATHOBIOLOGY, 90(1), 22-30, 202301
- Hepatic venous pressure gradient after balloon-occluded retrograde transvenous obliteration and liver stiffness measurement predict the prognosis of patients with gastric varices, BMC GASTROENTEROLOGY, 22(1), 20221222
- Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets, NATURE COMMUNICATIONS, 13(1), 20221029
- Comprehensive analysis of full-length transcripts reveals novel splicing abnormalities and oncogenic transcripts in liver cancer, PLOS GENETICS, 18(8), 202208
- ★, The presence of vessels encapsulating tumor clusters is associated with an immunosuppressive tumor microenvironment in hepatocellular carcinoma, INTERNATIONAL JOURNAL OF CANCER, 151(12), 2278-2290, 20221215
- Analysis of Lenvatinib's Efficacy against Intermediate-Stage Unresectable Hepatocellular Carcinoma, CANCERS, 14(20), 202210
- ★, Molecular Signature Predictive of Long-Term Liver Fibrosis Progression to Inform Antifibrotic Drug Development, GASTROENTEROLOGY, 162(4), 1210-1225, 202204
- The effect of the skin-liver capsule distance on the accuracy of ultrasound diagnosis for liver steatosis and fibrosis, JOURNAL OF MEDICAL ULTRASONICS, 49(3), 443-450, 202207
- Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease, SCIENCE TRANSLATIONAL MEDICINE, 14(650), 20220622
- HBV upregulates TRAIL-R3 expression in hepatocytes for escaping both cell apoptosis and suppression of their replication by TRAIL, J Infect Dis, 2022
- Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population, Oncotarget, 10(41), 4139-4148, 2019
- Pathological Complete Response to Lenvatinib after Failure of Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma, Liver Cancer, 202111
- ★, Molecular Signature Predictive of Long-Term Liver Fibrosis Progression to Inform Antifibrotic Drug Development, 162(4), 1210-1225, 202204
- Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease, Sci Transl Med, 14, 202206
- Efficacy and safety of chemoradiation therapy using one-shot cisplatin via hepatic arterial infusion for advanced hepatocellular carcinoma with major macrovascular invasion: a single-arm retrospective cohort study, BMC GASTROENTEROLOGY, 22(1), 20220602
- Construction of an anti-hepatitis B virus preS1 antibody and usefulness of preS1 measurement for chronic hepatitis B patients Anti-HBV PreS1 antibody, JOURNAL OF INFECTION, 84(3), 391-399, 202203
- Benign Recurrent Intrahepatic Cholestasis Type 1 with Novel Nonsense Mutations in the ATP8B1 Gene, CASE REPORTS IN GASTROENTEROLOGY, 16(1), 110-115, 2022
- ★, Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy, Cellular and Molecular Gastroenterology and Hepatology, 1(5), 516-534, 2015
- ★, Long-term continuous entecavir therapy in nucleos(t)ide-naïve chronic hepatitis B patients, J Hepatol, 57((3),), 508-514, 2012
- Development of hepatocellular carcinoma in patients with hepatitis C virus infection who achieved sustained virological response following interferon therapy: A large-scale, long-term cohort study, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(5), 1009-1015, 201605
- Improvement of renal dysfunction in a patient with hepatitis C virus-related liver cirrhosis by daclatasvir and asunaprevir combination therapy: A case report, HEPATOLOGY RESEARCH, 46(9), 944-948, 201608
- Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection, JOURNAL OF GASTROENTEROLOGY, 51(11), 1073-1080, 201611
- Effects of ITPA polymorphism on decrease of hemoglobin during simeprevir, peg-interferon, and ribavirin combination treatment for chronic hepatitis C, HEPATOLOGY RESEARCH, 46(12), 1256-1263, 201611
- The relationship between HBcrAg and HBV reinfection in HBV related post-liver transplantation patients, JOURNAL OF GASTROENTEROLOGY, 52(3), 366-375, 201703
- Hepatitis C-related hepatocellular carcinoma in the era of new generation antivirals, BMC MEDICINE, 15, 20170314
- Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy., J Gastroenterol. 2017 May 4. doi: 10.1007/s00535-017-1348-8., 20170504
- The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy, PLOS ONE, 12(8), 20170810
- Serum HMGB1 concentrations at 4 weeks is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy, JOURNAL OF GASTROENTEROLOGY, 53(1), 107-118, 201801
- Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease, JOURNAL OF GASTROENTEROLOGY, 53(2), 269-280, 201802
- Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients, INTERNATIONAL JOURNAL OF CANCER, 142(7), 1418-1426, 20180401
- Cell type-specific pharmacological kinase inhibition for cancer chemoprevention, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 14(2), 317-325, 201802
- miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis, GUT, 67(5), 953-962, 201805
- ★, Persisting risk of hepatocellular carcinoma after hepatitis C virus cure monitored by a liver transcriptome signature, 66(4), 1344-1346, 20170408
- Real-world efficacy of glecaprevir plus pibrentasvir for chronic hepatitis C patient with previous direct-acting antiviral therapy failures, JOURNAL OF GASTROENTEROLOGY, 54(3), 291-296, 201903
- HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response, GASTROENTEROLOGY, 156(8), 2313-+, 201906
- Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes, CANCER CELL, 35(6), 932-+, 20190610
- Comparison of intracellular responses between HBV genotype A and C infection in human hepatocyte chimeric mice, JOURNAL OF GASTROENTEROLOGY, 54(7), 650-659, 201907
- Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice, . J Gen Virol., 100(7), 1123-1131, 201907
- Genomic landscape of epithelium with low-grade atypia on gastric cancer after Helicobacter pylori eradiation therapy, JOURNAL OF GASTROENTEROLOGY, 54(10), 907-915, 201910
- eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA, SCIENTIFIC REPORTS, 9, 20191022
- Pruritus in patients with chronic liver disease and serum autotaxin levels in patients with primary biliary cholangitis, BMC GASTROENTEROLOGY, 19(1), 20191024
- Successful retreatment with 12 weeks of glecaprevir and pibrentasvir for a genotype 2a HCV-infected hemodialysis patient who failed to respond to 8 weeks of prior glecaprevir and pibrentasvir therapy, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(2), 267-270, 202004
- Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations, EBIOMEDICINE, 53, 202003
- Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese Population, CANCERS, 12(2), 202002
- ★, Circulating cytokines and angiogenic factors based signature associated with the relative dose intensity during treatment in patients with advanced hepatocellular carcinoma receiving lenvatinib, THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 12, 202005
- Incidence of microsatellite instability-high hepatocellular carcinoma among Japanese patients and response to pembrolizumab, HEPATOLOGY RESEARCH, 50(7), 885-888, 202007
- Tumor Fibroblast Growth Factor Receptor 4 Level Predicts the Efficacy of Lenvatinib in Patients With Advanced Hepatocellular Carcinoma, CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 11, 202005
- Risk factors for histological progression of non-alcoholic steatohepatitis analyzed from repeated biopsy cases, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 35(8), 1412-1419, 202008
- Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability, CLINICAL JOURNAL OF GASTROENTEROLOGY, 13(5), 867-872, 202010
- Impact of viral eradication by direct-acting antivirals on the risk of hepatocellular carcinoma development, prognosis, and portal hypertension in hepatitis C virus-related compensated cirrhosis patients, HEPATOLOGY RESEARCH, 50(11), 1222-1233, 202011
- Real-world efficacy of sofosbuvir plus velpatasvir therapy for patients with hepatitis C virus-related decompensated cirrhosis, HEPATOLOGY RESEARCH, 50(11), 1234-1243, 202011
- Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model, CANCER LETTERS, 498, 111-120, 20210201
- Abatacept treatment for patients with severe acute hepatitis caused by hepatitis B virus infection-Pilot study, JOURNAL OF VIRAL HEPATITIS, 28(2), 400-409, 202102
- Signal Activation of Hepatitis B Virus-Related Hepatocarcinogenesis by Up-regulation of SUV39h1, JOURNAL OF INFECTIOUS DISEASES, 222(12), 2061-2070, 20201215
- yRibavirin induces hepatitis C virus genome mutations in chronic hepatitis patients who failed to respond to prior daclatasvir plus asunaprevir therapy, JOURNAL OF MEDICAL VIROLOGY, 92(2), 210-218, 202002
- Novel drug resistance-associated substitutions against pibrentasvir emerged in genotype 1b hepatitis C virus-infected human hepatocyte transplanted mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 559, 78-83, 20210625
- Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma, GUT, 70(1), 157-169, 202101
- In vitro analysis of hepatic stellate cell activation influenced by transmembrane 6 superfamily 2 polymorphism, MOLECULAR MEDICINE REPORTS, 23(1), 202101
- ★, Identification and monitoring of mutations in circulating cell-free tumor DNA in hepatocellular carcinoma treated with lenvatinib, JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 40(1), 20210626
- Increasing incidence of non-HBV- and non-HCV-related hepatocellular carcinoma: single-institution 20-year study, BMC GASTROENTEROLOGY, 21(1), 20210731
- Serum PreS1 and HBsAg ratio reflects liver fibrosis and predicts the development of hepatocellular carcinoma in chronic hepatitis B patients, JOURNAL OF VIRAL HEPATITIS, 28(9), 1304-1311, 202109
- Analysis of Survival and Response to Lenvatinib in Unresectable Hepatocellular Carcinoma, CANCERS, 14(2), 202201
Invited Lecture, Oral Presentation, Poster Presentation
- Alteration of gene expression after entecavir and pegylated interferon therapy in HBV infected chimeric mouse liver, 2023 International HBV meeting, 2023/09/21, Without Invitation, English
- The Inpact of Bevacizumab Withdrawal on Prognosis in Atezolizmab + Bevacizumab Combiation Therapy for Unresectable Hepatocellular Carcinoma, APASL Oncology 2023 Sendai, 2023/10/27, Without Invitation, English
- Effectiveness of Repeated Stereotactic Body Radiation Therapy for Hepetocellular Carcinoma, APASL Oncology 2023 Sendai, 2023/10/27, Without Invitation, English
- Circulating cell free tumor DNA analysis in advanced hepatocellular carcinoma treated with Lenvatinib,, Atsushi Ono, Yasutoshi Fujii, C. Nelson Hayes, Masami Yamauchi, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Daiki Miki, Tomokazu Kawaoka, Michio Imamura, Wataru Okamoto, Kazuaki Chayama and Hiroshi Aikata, 2021/11/12, Without Invitation, English
- A COMPREHENSIVE ANALYSIS OF A WIDE RANGE OF LIVER DISEASES BY 16S rRNA SEQUENCING REVEALS CHARACTERISTIC PATTERNS OF GUT MICROBIOTA IN EACH ETIOLOGY, Daiki Miki, Yumi Shimomura, Nelson Hayes, Hiromi Abe-Chayama, Hatsue Fujino, Maiko Numba, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Grace Naswa Makokha, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/11, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, United State
- INDEPENDENT IMPACT OF POLYMORPHISM IN IRF5 AS WELL AS STAT4 ON HBV-RELATED HEPATOCARCINOGENESIS, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, Nelson Hayes, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/11, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, United State
- ASSOCIATION OF FNDC5, PNPLA3 AND TM6SF2 POLYMORPHISMS WITH HEPATIC STEATOSIS IN NAFLD PATIENTS, Daiki Miki, Takashi Nakahara, Eisuke Murakami, Hiromi Abe-Chayama, Hatsue Fujino, Atsushi Ono, Masami Yamauchi, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Nelson Hayes, Grace Naswa Makokha, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/10, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, USA
- DIFFERENTIAL EFFECTS OF HOST GENETIC FACTORS ON HCV PERSISTENCE ACCORDING TO HCV GENOTYPES, Daiki Miki, Tomokazu Kawaoka, Nelson Hayes, Hiromi Abe-Chayama, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/10, Without Invitation, English, American Association for the Study of Liver Diseases
- RESISTANCE ANALYSIS FOR GLECAPREVIR AND PIBRENTASVIR ON GENOTYPE 1b HEPATITIS C VIRUS INFECTION IN SUBGENOMIC REPLICON SYSTEMS AND HUMAN HEPATOCYTE TRANSPLANTED MICE, Mitsutaka Osawa, Michio Imamura, Takuro Uchida, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Akira Hiramatsu, Hiromi Abe-Chayama, Nelson Hayes, Grace Naswa Makokha, Hiroshi Aikata, Yuji Ishida, Chise Tateno, Yohei Miyayama, Makoto Hijikata, Kazuaki Chayama, The Liver Meeting 2019, The Liver Meeting 2019, 2019/11/10, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, USA
- TUMOR AND BLOOD FGFR4 LEVELS PREDICT THE EFFICACY OF LENVATINIB IN PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA, Masami Yamauchi, Atsushi Ono, Haruna Hatooka, Kenichiro Kodama, Peiyi Zhang, Yuji Teraoka, Kei Morio, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Daiki Miki, Tomokazu Kawaoka, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Clair Nelson Hayes, Hiroshi Aikata, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/09, Without Invitation, English, American Association for the Study of Liver Diseases
- PERMISSION OF HEPATITIS B VIRUS INFECTION IN Jak3KORag2KO MOUSE, Yuji Teraoka, Michio Imamura, Takuro Uchida, Kazuki Ohya, Mitsutaka Osawa, Kei Morio, Hatsue Fujino, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Masataka Tsuge, Daiki Miki, Akira Hiramatsu, Hiromi Abe-Chayama, Nelson Hayes, Yuji Ishida, Chise Tateno, Hiroshi Aikata, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/09, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, USA
- GENETIC POLYMORPHISM OF IP-10, NOT IFNL4 OR HLA-DPS, AFFECTS LIVER INFLAMMATION IN CHRONIC HEPATITIS B PATIENTS, Daiki Miki, Masataka Tsuge, Hiromi Abe-Chayama, Nelson Hayes, Hatsue Fujino, Grace Naswa Makokha, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Tomokazu Kawaoka, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/08, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, USA
- EXPLORATORY ANALYSIS OF BIOMARKERS ASSOCIATED WITH CLINICAL OUTCOMES OF LENVATINIB IN HEPATOCELLULAR CARCINOMA, Atsushi Ono, Hiroshi Aikata, Masami Yamauchi, Kenichiro Kodama, Daiki Miki, Waka Ohishi, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Eisuke Murakami, Tomokazu Kawaoka, Hiromi Abe-Chayama, Masataka Tsuge, Michio Imamura, Clair Nelson Hayes, Kazuaki Chayama, The Liver Meeting 2019, 2019/11/08, Without Invitation, English, American Association for the Study of Liver Diseases, Boston, USA
- The SNP allele corresponding to higher IRF5 expression reduces susceptibility to HBV-related hepatocellular carcinoma, Daiki Miki, Masataka Tsuge, Masami Yamauchi, Atsushi Ono, Hiroshi Aikata, Tatsuhiko Tsunoda, Kazuaki Chayama, The 78th Annual Meeting of the Japanese Cancer Association, 2019/09/26, Without Invitation, English, Japanese Cancer Association, Kyoto, Japan
- Multiple genetic factors affecting nonalcoholic fatty liver disease and nonalcoholic steatohepatitis-related hepatocellular carcinoma in the Japanese population, Daiki Miki, Yuichi Hiyama, Atsushi Ono, Masami Yamauchi, Masataka Tsuge, Hiroshi Aikata, Tatsuhiko Tsunoda, Kazuaki Chayama, 11th AACR-JCA Joint Conference, 2019/02/10, Without Invitation, English, American Association for Cancer Research, Japanese Cancer Association, Maui, Hawaii, USA
- Association of TLL1 Polymorphism with Development of Hepatocellular Carcinoma after Hepatitis C Virus Eradication and Fibrosis Severity, Daiki Miki, Tomokazu Kawaoka, Yuko Nagaoki, Nelson Hayes, Atsushi Ono, Takashi Nakahara, Eisuke Murakami, Masami Yamauchi, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Hiroshi Aikata, Hiromi Abe-Chayama, Hidenori Ochi, Tatsuhiko Tsunoda, Kazuaki Chayama, The Liver Meeting 2018, 2018/11/10, Without Invitation, English, American Association for the Study of Liver Diseases
- Serum HMGB1 concentrations is a useful predictor of extreme poor prognosis for advanced hepatocellular carcinoma treated with sorafenib and hepatic arterial infusion chemotherapy, The Liver Meeting 2017, 2017/10/22, Without Invitation, English, other
- Hepatic stellate cell-targeted pharmacological EGFR inhibition for HCC chemoprevention, The Liver Meeting 2017, 2017/10/20, Without Invitation, English, other
- Serial profiling of circulating tumor DNA identifies biomarkers for anti-VEGF chemotherapy in mCRC patients, Yamauchi, Masami; Chayama, Kazuaki; Urabe, Yuji; Ono, Atsushi; Ochi, Hidenori; Miki, Daiki, 2017 Annual Meeting of the Japanese-Society-of-Medical-Oncology, 2017/07, Without Invitation, Japanese, Japanese-Society-of-Medical-Oncology
- Japanese genetic study could not suggest the importance of the NTCP locus for HBV persistence, Miki D, Ochi H, Hayes CN, Abe H, Akamatsu S, Ono A, Nakahara T, Zhang Y, Masaki K, Fujino H, Miyaki E, Kan H, Uchida T, Hiraga N, Tsuge M, Kawaoka T, Imamura M, Kawakami Y, Aikata H, Chayama K, The 25th Conference of the Asian Pacific Association for the Study of the Liver, 2016/02/22, Without Invitation, English, Asian Pacific Association for the Study of the Liver (APASL)
- The relationship between hepatocellular carcinoma development and reduced expression levels of the major germline genotype of PROSC, which is frequently deleted in hepatocellular carcinoma, Miki, Daiki; Ochi, Hidenori; Hayes, C. Nelson; Abe, Hiromi; Akamatsu, Sakura; Ono, Atsushi; Nakahara, Takashi; Zhang, Yizhou; Masaki, Keiichi; Fujino, Hatsue; Miyaki, Eisuke; Kan, Hiromi; Uchida, Takuro; Hiraga, Nobuhiko; Tsuge, Masataka; Kawaoka, Tomokazu; Imamura, Michio; Kawakami, Yoshiiku; Aikata, Hiroshi; Chayama, Kazuaki, 66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), 2015/11, Without Invitation, English, American-Association-for-the-Study-of-Liver-Diseases (AASLD)
- Circulating tumor DNA analysis for liver cancers and its usefulness as a liquid biopsy, Ono A, Hayes CN, Uchida T, Kan H, Masaki K, Nakahara T, Miki D, Kawaoka T, Tsuge M, Hiraga N, Imamura M, Kawakami Y, Aikata H, Ochi H, Abe H, Nakagawa H, Chayama K, AASLD the LIVER MEETING, San Francisco, CA, November 2015., 2015, Without Invitation, English
- The IL28B SNP has a stronger regulatory effect on the expression of OAS1 than a nearby SNP located downstream of OAS1 in chronic HCV patients, Miki, Daiki; Abe, Hiromi; Hayes, C. Nelson; Ochi, Hidenori; Kawaoka, Tomokazu; Akamatsu, Sakura; Ono, Atsushi; Nakahara, Takashi; Seki, Noriaki; Murakami, Eisuke; Zhang, Yizhou; Uchida, Takuro; Honda, Yohji; Masaki, Keiichi; Kan, Hiromi; Tsuge, Masataka; Hiraga, Nobuhiko; Imamura, Michio; Kawakami, Yoshiiku; Aikata, Hiroshi; Kubo, Michiaki; Chayama, Kazuaki, 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, 2014/11, Without Invitation, English
- A single amino acid substitution in HLA-DQB1 as well as an IFNL4 variant strongly affect susceptibility to chronic hepatitis C, Miki, Daiki; Ochi, Hidenori; Takahashi, Atsushi; Hayes, C. Nelson; Urabe, Yuji; Abe, Hiromi; Ono, Atsushi; Akamatsu, Sakura; Nakahara, Takashi; Seki, Noriaki; Murakami, Eisuke; Zhang, Yizhou; Uchida, Takuro; Honda, Yohji; Yoshimi, Satoshi; Kobayashi, Tomoki; Masaki, Keiichi; Kan, Hiromi; Kawaoka, Tomokazu; Tsuge, Masataka; Hiraga, Nobuhiko; Imamura, Michio; Kawakami, Yoshiiku; Aikata, Hiroshi; Takahashi, Shoichi; Akuta, Norio; Suzuki, Fumitaka; Ikeda, Kenji; Kumada, Hiromitsu; Karino, Yoshiyasu; Toyota, Joji; Tsunoda, Tatsuhiko; Kubo, Michiaki; Kamatani, Naoyuki; Nakamura, Yusuke; Chayama, Kazuaki, 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, 2014/11, Without Invitation, English
- Two microRNA polymorphisms are associated with hepatitis B virus-related but not hepatitis C virus-related hepatocellular carcinoma in the Japanese population, Miki, Daiki; Ochi, Hidenori; Hayes, C. Nelson; Abe, Hiromi; Kawaoka, Tomokazu; Ono, Atsushi; Akamatsu, Sakura; Nakahara, Takashi; Seki, Noriaki; Murakami, Eisuke; Zhang, Yizhou; Uchida, Takuro; Honda, Yohji; Masaki, Keiichi; Kan, Hiromi; Tsuge, Masataka; Hiraga, Nobuhiko; Imamura, Michio; Kawakami, Yoshiiku; Aikata, Hiroshi; Kubo, Michiaki; Chayama, Kazuaki, 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, 2014/11, Without Invitation, Japanese
- Analysis Of Circulating Tumor DNA In Hepatocellular Carcinoma, International Liver Cancer Association 8th Annual Conference, 5–7 September 2014, Kyoto, Japan, 2014/09/05, Without Invitation, English
- Analysis Of Circulating Tumor DNA In Hepatocellular Carcinoma, Ono A, Aikata H, Chayama K, International Liver Cancer Association 8th Annual Conference, 2014, Without Invitation, English
- Antiviral effect of tenofovir disoproxil fumarate on drug-resistant HBV clones and different susceptibility between HBV genotype A and C, Murakami, Eisuke; Tsuge, Masataka; Hiraga, Nobuhiko; Kawaoka, Tomokazu; Ono, Atsushi; Miki, Daiki; Abe, Hiromi; Imamura, Michio; Aikata, Hiroshi; Ochi, Hidenori; Hayes, C. Nelson; Chayama, Kazuaki, 64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases, 2013/11, Without Invitation, English
- Exploratory analysis of biomarkers associated with clinical outcomes in advanced HCC patients receiving lenvatinib, The 79th Annual Meeting of the Japanese Cancer Association, Without Invitation, Japanese
- Germline variants of highly point-mutated genes in hepatocellular carcinoma do not have strong effects on HCV-related hepatocarcinogenesis, Miki, Daiki; Ochi, Hidenori; Hayes, C. Nelson; Ono, Atsushi; Akamatsu, Sakura; Urabe, Yuji; Masaki, Keiichi; Abe, Hiromi; Kawaoka, Tomokazu; Nakahara, Takashi; Seki, Noriaki; Murakami, Eisuke; Zhang, Yizhou; Uchida, Takuro; Honda, Yohji; Kan, Hiromi; Tsuge, Masataka; Hiraga, Nobuhiko; Imamura, Michio; Kawakami, Yoshiiku; Aikata, Hiroshi; Kubo, Michiaki; Chayama, Kazuaki, 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Without Invitation, Japanese
External Funds
Acceptance Results of Competitive Funds
- 2022/04/01, 2024/03/31
- Grants-in-Aid for Scientific Research, 2020, 2021
- KAKENHI(Grant-in-Aid for Young Scientists (B)), 2017, 2019
Social Activities
History as Peer Reviews of Academic Papers
- 2023, Liver international, Others, 1
- 2023, Hepatology Research, Others, 1
- 2023, Cancer Science, Others, 1
- 2023, Scientific Reports, Others, 1
- 2023, Cancer Reports, Others, Reviewer, 1
- 2022, Liver Internationalnternational, Others
- 2022, Cancer Science, Others, Reviewer, 1
- 2021, Kanzo, Others, Reviewer, 3
- 2021, Frontiers in Immunology, Others, Reviewer, 1
- 2021, Journal of gastroenterology, Others, Reviewer, 1
- 2021, Journal of Hepatocellular Carcinoma, Others, Reviewer, 1
- 2021, Expert Review of Gastroenterology & Hepatology, Others, Reviewer, 1
- 2022, Kanzo, Others, Reviewer, 6
- 2022, Liver Cancer, Others, Reviewer, 1
- 2022, Journal of Hepatocellular carcinoma, Others, Reviewer, 1
- 2022, Expert Review of Gastroenterology & Hepatology, Others, Reviewer, 1
- 2022, Clinical Gastroenterology and Hepatology, Others, Reviewer, 1
- 2022, Cancers, Others, 1
- 2020, Journal of Gastroenterology, Others, 1
- 2020, Genome Medicine, Others, 1
- 2020, Cancer Management and Research, Others, reviewer, 1
- 2021, Computational and Structural Biotechnology Journal, Others, reviewer, 1
- 2021, Cancer Management and Research, Others, reviewer, 1