HIDEHIKO TAKIGAWA

Last Updated :2026/11/05

Affiliations, Positions
Endoscopy Center, Associate Professor/Lecturer
E-mail
hidehikohiroshima-u.ac.jp
Self-introduction
My research focuses on bridging basic science with clinical application. In the field of basic research, I investigate the interaction between cancer and the tumor microenvironment, the mechanisms of anti-tumor chemotherapy, and drug repositioning. My clinical work centers on diseases associated with Non-helicobacter pylori Helicobacter (NHPH) infection, gastrointestinal malignant lymphoma, and the relationship between gastritis and carcinogenesis.

Basic Information

Major Professional Backgrounds

  • 2026/10/01, Hiroshima University Hospital, Endoscopy Center, Lecturer
  • 2024/06/01, 2026/09/30, Hiroshima University Hospital, Endoscopy Center, Clinical Lecturer
  • 2021/10/01, 2026/09/30, Hiroshima University Hospital, Department of Endoscopy, Assistant Professor
  • 2020/04/01, 2021/09/30, Hiroshima University Hospital, Department of Gastroenterology, Clinical Fellow
  • 2013/04/01, 2013/10/31, Hiroshima University Hospital, Department of Gastroenterology, Clinical Fellow

Academic Degrees

  • Hiroshima University

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2026, Undergraduate Education, Intensive, Introduction to clinical clerkship
  3. 2026, Undergraduate Education, Intensive, Practice for medical research
  4. 2026, Undergraduate Education, Intensive, Practice of Medicine I
  5. 2026, Undergraduate Education, Intensive, Practice of Medicine II
  6. 2026, Undergraduate Education, First Semester, Internal Medicine I

Research Activities

Academic Papers

  1. Gel Immersion Endoscopic Mucosal Resection With Submucosal Injection for Superficial Esophageal Squamous Neoplasms (With Video)., DEN open, 7(1), 2027
  2. Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into Cancer-Associated Fibroblasts and Promote Tumor Growth in Renal Cell Carcinoma., Cancers, 18(11), 2026
  3. ★, Increased Extracolonic Cancer Incidence and Mortality in Patients with Serrated Polyposis Syndrome with a History of Colorectal Cancer: A Comparative Cohort Study., Digestion, 2026
  4. Gel immersion endoscopic mucosal resection for superficial esophageal cancer in a patient with pharyngoesophageal stenosis., Endoscopy, 2026
  5. Association Between Arterial Calcification and Small Bowel Vascular Lesions: A Comparative Study of Angioectasia and Dieulafoy's Lesions., Digestive diseases and sciences, 2026
  6. High-resolution Spatial Transcriptomics Reveals Contrasting Tumor States in Two Early Gastric Cancers., Anticancer research, 46(11), 2026
  7. ★, A Three-Way Comparison of Nodular Lesions in H. pylori-Induced Gastritis, Non-Helicobacter pylori Helicobacter (NHPH)-Induced Gastritis, and NHPH-Induced MALT Lymphoma Reveals Their Distinct Endoscopic Predictors: Distribution for Bacterial Etiology and Morphology for Malignancy., Helicobacter, 30(5), 2025
  8. ★, Clinical utility of repeated IgH gene rearrangement testing for the diagnosis and surveillance of gastric MALT lymphoma, SCIENTIFIC REPORTS, 15(1), 20250827
    Link to Paper Search Results by DOI
  9. Efficacy of Hybrid Endoscopic Submucosal Dissection to Ensure Adequate Submucosal Layer for T1b Colorectal Carcinomas of 20-30 mm in Diameter., Journal of the anus, rectum and colon, 9(3), 2025
  10. Efficacy of Hybrid Endoscopic Submucosal Dissection to Ensure Adequate Submucosal Layer for T1b Colorectal Carcinomas of 20-30 mm in Diameter, JOURNAL OF THE ANUS RECTUM AND COLON, 9(3), 295-301, 2025
    Link to Paper Search Results by DOI
  11. Lymphangiogenesis in the Deepest Invasive Areas of Human Early-Stage Colorectal Cancer., International journal of molecular sciences, 26(7), 2025
  12. ★, Endoscopic features differentiating non-Helicobacter pylori Helicobacter-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance and H. pylori-induced conventional nodular gastritis., Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2025
  13. ★, Clinical Outcomes of Endoscopic Submucosal Dissection for Early Gastric Cancer Patients With Concurrent Advanced Malignancies With Expected Poor Prognosis, JGH OPEN, 9(7), 202507
    Link to Paper Search Results by DOI
  14. ★, Helicobacter pylori-positive colorectal MALT lymphoma with repeated metachronous recurrence after a complete response to eradication therapy and regression after a watch-and-wait strategy., Internal medicine (Tokyo, Japan), 2025
  15. Efficiency of Real-time Computer-aided Polyp Detection during Surveillance Colonoscopy: A Pilot Study, Journal of the Anus, Rectum and Colon, 9(1), 127-133, 20250101
  16. Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas, DEN OPEN, 5(1), 202504
    Link to Paper Search Results by DOI
  17. Clinical usefulness of hybrid endoscopic submucosal dissection for T1b colorectal carcinomas ≤20 mm to ensure adequate vertical margins, DEN OPEN, 5(1), 202504
    Link to Paper Search Results by DOI
  18. Clinical usefulness and acceptability of small-bowel capsule endoscopy with panoramic imaging compared with axial imaging in Japanese patients, DEN Open, 5(1), 20250401
  19. A case of esophageal squamous cell carcinoma with epidermization showing a unique morphology., Clinical journal of gastroenterology, 18(1), 2025
  20. Investigating tumor-infiltrating lymphocytes as predictors of lymph node metastasis in deep submucosal invasive esophageal squamous cell carcinoma: a retrospective cross-sectional study., Journal of gastroenterology, 2025
  21. Efficacy of Hybrid Endoscopic Submucosal Dissection to Ensure Adequate Submucosal Layer for T1b Colorectal Carcinomas of 20-30 mm in Diameter., Journal of the anus, rectum and colon, 9(3), 2025
  22. Efficiency of Real-time Computer-aided Polyp Detection during Surveillance Colonoscopy: A Pilot Study., Journal of the anus, rectum and colon, 9(1), 2025
  23. Clinical Significance of Small-Bowel Mucosal Changes in Liver Cirrhosis Patients With Suspected Small-Bowel Bleeding: A Capsule Endoscopy Study., Journal of gastroenterology and hepatology, 2025
  24. Lymph node metastasis and treatment outcomes of endoscopic submucosal dissection for superficial spreading esophageal squamous cell carcinoma ≥ 50 mm in size., Esophagus : official journal of the Japan Esophageal Society, 2025
  25. Comparative analyses of short- and long-term outcomes between endoscopic submucosal dissection and endoscopic laryngo-pharyngeal surgery for superficial pharyngeal carcinomas., DEN open, 5(1), 2025
  26. ★, Analysis of anti-tumor effect and mechanism of GLS1 inhibitor CB-839 in colorectal cancer using a stroma-abundant tumor model., Experimental and molecular pathology, 137, 20240503
  27. ★, A Proton Pump Inhibitor Independently Elevates Gastrin Levels as a Marker for Metachronous Gastric Cancer After Endoscopic Submucosal Dissection, Journal of Clinical Medicine, 13(21), 20241101
  28. WEE1 Inhibitor Adavosertib Exerts Antitumor Effects on Colorectal Cancer, Especially in Cases with p53 Mutations, Cancers, 16(18), 20240901
  29. Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 39(1), 20240816
    Link to Paper Search Results by DOI
  30. Predictive factors of portal hypertensive enteropathy exacerbations based on long-term outcomes, BMC GASTROENTEROLOGY, 24(1), 20240826
    Link to Paper Search Results by DOI
  31. Predictive factors for esophageal stenosis in patients receiving prophylactic steroid therapy after endoscopic submucosal dissection for esophageal squamous cell carcinoma, BMC Gastroenterology, 24(1), 20241201
  32. Pexidartinib and Immune Checkpoint Inhibitors Combine to Activate Tumor Immunity in a Murine Colorectal Cancer Model by Depleting M2 Macrophages Differentiated by Cancer-Associated Fibroblasts, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(13), 202407
    Link to Paper Search Results by DOI
  33. Long-term prognosis after endoscopic submucosal dissection for esophageal cancer in older adult patients, BMC Gastroenterology, 24(1), 20241201
  34. Long-term outcomes of patients with obscure gastrointestinal bleeding after negative capsule endoscopy, Journal of Gastroenterology and Hepatology (Australia), 39(1), 165-171, 20240101
  35. Hybrid endoscopic submucosal dissection as a salvage option for difficult colorectal conventional endoscopic submucosal dissection, Surgical Endoscopy, 38(1), 222-228, 20240101
  36. Genetic Analysis of Biopsy Tissues from Colorectal Tumors in Patients with Ulcerative Colitis, Cancers, 16(19), 20241001
  37. Fructose-bisphosphate Aldolase C Expression is Associated with Poor Prognosis and Stemness in Gastric Cancer, Acta Histochemica et Cytochemica, 57(5), 165-174, 20240101
  38. Comparative prediction of lymph node metastasis in pT1 colorectal cancer among Western and Japanese guidelines, FRONTIERS IN ONCOLOGY, 14, 20241031
    Link to Paper Search Results by DOI
  39. Clinicopathological and genomic features of superficial esophageal squamous cell carcinomas in nondrinker, nonsmoker females, CANCER MEDICINE, 13(4), 202402
    Link to Paper Search Results by DOI
  40. Clinicopathological and genomic features of superficial esophageal squamous cell carcinomas in nondrinker, nonsmoker females, Cancer Medicine, 13(4), 20240201
  41. Clinicopathologic Features of Early Gastric Cancer after Heli-cobacter pylori Eradication in Japanese Patients: Comparative Study between Early (<10 Years) and Late (>10 Years) Onset, Cancers, 16(18), 20240901
  42. Clinical factors associated with stable treatment of chronic constipation in Japanese patients, BMC Gastroenterology, 24(1), 20241201
  43. Can underwater endoscopic mucosal resection be an alternative to conventional endoscopic mucosal resection for superficial non-ampullary duodenal epithelial tumors?, DEN OPEN, 4(1), 202404
    Link to Paper Search Results by DOI
  44. A case of esophageal squamous cell carcinoma with epidermization showing a unique morphology, Clinical Journal of Gastroenterology, 20240101
  45. Vertical margin distance in T1 colorectal carcinoma resected by endoscopic submucosal dissection affects prognosis after additional surgery., International journal of colorectal disease, 39(1), 2024
  46. Predictive factors of portal hypertensive enteropathy exacerbations based on long-term outcomes., BMC gastroenterology, 24(1), 2024
  47. WEE1 Inhibitor Adavosertib Exerts Antitumor Effects on Colorectal Cancer, Especially in Cases with p53 Mutations., Cancers, 16(18), 2024
  48. ★, Comprehensive Analysis of Gene Expression Profiling to Explore Predictive Markers for Eradication Therapy Efficacy against Helicobacter pylori-Negative Gastric MALT Lymphoma, CANCERS, 15(4), 202302
    Link to Paper Search Results by DOI
  49. ★, The Anti-Tumor Effect of the Newly Developed LAT1 Inhibitor JPH203 in Colorectal Carcinoma, According to a Comprehensive Analysis, Cancers, 15(5), 20230301
  50. ★, No significant association between non-Helicobacter pylori Helicobacter infection with gastritis-related indices and gastric cancer, American Journal of the Medical Sciences, 366(6), 421-429, 20231201
  51. ★, Diagnostic performance of the normal range of gastrin calculated using strict criteria based on a combination of serum markers and pathological evaluation for detecting gastritis: a retrospective study, BMC Gastroenterology, 23(1), 20231201
  52. ★, Synchronous gastric MALT lymphoma and gastric adenocarcinoma of fundic gland type arising from a hamartomatous inverted polyp in a Helicobacter pylori naive patient, Clinical Journal of Gastroenterology, 16(4), 521-526, 20230801
  53. Investigating the Role of Tumor-Infiltrating Lymphocytes as Predictors of Lymph Node Metastasis in Deep Submucosal Invasive Colorectal Cancer: A Retrospective Cross-Sectional Study, Cancers, 15(21), 20231101
  54. Endoscopic findings suggestive of a high risk of non-radical cure after definitive chemoradiotherapy for cT1bN0M0 esophageal squamous cell carcinoma, Esophagus, 20(3), 541-547, 20230701
  55. Efficacy of the specialized scissor-type knife for gastric endoscopic submucosal dissection: a propensity score matched retrospective study., Endoscopy international open, 11(4), 2023
  56. Disease surveillance evaluation of primary small-bowel follicular lymphoma using capsule endoscopy images based on a deep convolutional neural network (with video), Gastrointestinal Endoscopy, 98(6), 968-976.e3, 20231201
  57. Usefulness and Educational Benefit of a Virtual Scale Endoscope in Measuring Colorectal Polyp Size, Digestion, 105(2), 73-80, 20230905
  58. Anti-tumor necrosis factor-alpha monoclonal antibody suppresses colorectal cancer growth in an orthotopic transplant mouse model, PLoS ONE, 18(3 MARCH), 20230301
  59. ★, Serum Gastrin and Pepsinogen Levels after Administration of Acid Secretion Inhibitors for Ulcers due to Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer., Gastroenterology research and practice, 2022, 20220128
  60. ★, Identification of Helicobacter pylori-related gastric cancer risk using serological gastritis markers and endoscopic findings: a large-scale retrospective cohort study., BMC gastroenterology, 22(1), 20220620
  61. Promoting mechanism of serum amyloid a family expression in mouse intestinal epithelial cells., PloS one, 17(3), 20220318
  62. Predictive factors for the progression of primary localized stage small-bowel follicular lymphoma., Journal of gastroenterology, 20220713
  63. Outcomes of endoscopic submucosal dissection in patients who develop metachronous superficial esophageal squamous cell carcinoma close to a post-endoscopic submucosal dissection scar., Esophagus : official journal of the Japan Esophageal Society, 20220802
  64. Investigation of endoscopic findings in nine cases of Helicobacter suis-infected gastritis complicated by gastric mucosa-associated lymphoid tissue lymphoma., Helicobacter, 20220627
  65. Anti-Programmed Cell Death-1 Antibody and Dasatinib Combination Therapy Exhibits Efficacy in Metastatic Colorectal Cancer Mouse Models, Cancers, 14(24), 20221201
  66. ★, Involvement of non-Helicobacter pylori helicobacter infections in Helicobacter pylori-negative gastric MALT lymphoma pathogenesis and efficacy of eradication therapy, Gastric Cancer, 24(4), 937-945, 20210701
  67. Stromal reaction inhibitor and immune-checkpoint inhibitor combination therapy attenuates excluded-type colorectal cancer in a mouse model, Cancer Letters, 498, 111-120, 20210201
  68. Role of tumor-associated macrophages at the invasive front in human colorectal cancer progression, Cancer Science, 112(7), 2692-2704, 20210701
  69. Mesenchymal stem cells induce tumor stroma formation and epithelial-mesenchymal transition through SPARC expression in colorectal cancer, Oncology Reports, 45(6), 20210601
  70. Gastric mucosa-associated lymphoid tissue lymphoma in conjunction with multiple lymphomatous polyposis in the context of Helicobacter pylori and Helicobacter suis superinfection, Clinical Journal of Gastroenterology, 14(2), 478-483, 20210401
  71. Characteristics and Treatment Outcomes of Small-bowel Angioectasia in Systemic Sclerosis Patients: A Retrospective Observational Study., Internal medicine (Tokyo, Japan), 20210824
  72. Serum amyloid A is a better predictive biomarker of mucosal healing than C-reactive protein in ulcerative colitis in clinical remission, BMC Gastroenterology, 20(1), 20200403
  73. Association between Helicobacter suis infection and the pathogenesis of gastric mucosa-associated lymphoid tissue lymphoma, Hiroshima Journal of Medical Sciences, 69(2), 33-37, 20200601
  74. Unusual complication of frailty: Superior mesenteric artery syndrome, Internal Medicine, 58(14), 2119-2120, 20190101
  75. ★, Helicobacter suis infection is associated with nodular gastritis-like appearance of gastric mucosa-associated lymphoid tissue lymphoma, Cancer Medicine, 8(9), 4370-4379, 20190801
  76. Watch-and-wait policy versus rituximab-combined chemotherapy in Japanese patients with intestinal follicular lymphoma, Journal of Gastroenterology and Hepatology (Australia), 33(8), 1461-1468, 20180801
  77. Silencing of Discoidin Domain Receptor-1 (DDR1) Concurrently Inhibits Multiple Steps of Metastasis Cascade in Gastric Cancer, Translational Oncology, 11(3), 575-584, 20180601
  78. ★, Mesenchymal Stem Cells Induce Epithelial to Mesenchymal Transition in Colon Cancer Cells through Direct Cell-to-Cell Contact, Neoplasia (United States), 19(5), 429-438, 20170501
  79. ★, Multikinase inhibitor regorafenib inhibits the growth and metastasis of colon cancer with abundant stroma, Cancer Science, 107(5), 601-608, 20160501
  80. A case of primary peritoneal carcinoma with gastric metastasis that was diagnosed by endosonography-guided fine needle aspiration, Gastroenterological Endoscopy, 55(11), 3562-3567, 20131101
  81. A case of acute hepatitis C with hepatitis C virus (HCV) genotype 3A -discussion of IL28-B-, Acta Hepatologica Japonica, 54(2), 120-127, 20130101

Invited Lecture, Oral Presentation, Poster Presentation

  1. Impact of Genetic Mutations and Mild Inflammation on Colorectal Tumorigenesis, Ishibashi K, Urabe Y, Uda T, Sako Y, Takasago T, Tanaka H, Tsuboi A, Yamashita K, Kishida Y, Hiyama Y, Takigawa H, Kuwai T, Hiroaki N, Takao H, Oka S., UEGW 2025, 2025/10/04, Without Invitation, English
  2. Diagnostic endoscopic characteristics of non-Helicobacter pylori Helicobacter-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance and Helicobacter pylori-induced conventional nodular gastritis, Kitadai Y, Takigawa H, Shimizu D, Ariyoshi M, Tsuboi A, Tanaka H, Yamashita K, Hiyama Y, Kishida Y, Urabe Y, Ishikawa A, Kuwai T, Oka S., JGES international 2025, 2025/09/05, Without Invitation, English
  3. Efficacy of image enhanced endoscopy using a novel double balloon enteroscope for visibility of small bowel lesions, Shigenobu S, Tsuboi A, Sugata S, Matsubara Y, Takasago T, Tanaka H, Yamashita K, Hiyama Y, Kishida Y, Takigawa H, Urabe Y, Kuwai T, Oka S., UEGW 2025, 2025/10/04, Without Invitation, English
  4. Efficacy and safety of cold snare polypectomy in intensive downstaging polypectomy for colorectal polyps as patients with familial adenomatous polyposis, Urabe Y, Ishibashi K, Uda T, Sako Y, Gurita T, Masuda S, Hatsushika Y, Nakamura T, Konishi H, Tsuboi A, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Kuwai T, Oka S., UEGW 2025, 2025/10/04, Without Invitation, English
  5. CLINICAL SIGNIFICANCE OF SMALL-BOWEL MUCOSAL CHANGES IN LIVER CIRRHOSIS PATIENTS WITH SUSPECTED SMALL-BOWEL BLEEDING: A CAPSULE ENDOSCOPY STUDY, Matsubara Y, Tsuboi A, Shigenobu S, Hirata I, Takasago T, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Kishida Y, Murakami E, Urabe Y, Tsuge M, Kuwai T, Oka S., UEGW 2025, 2025/10/04, Without Invitation, English
  6. Investigating tumor-infiltrating lymphocytes as predictors of lymph node metastasis in deep submucosal invasive esophageal squamous cell carcinoma : a retrospective cross-sectional study, Konishi H, Urabe Y, Hatsushika Y, Masuda K, Nakamura T, Ishibashi K, Takasago T, Tanaka H, Tsuboi A, Yamashita K, Hiyama Y, Kishida Y, Takigawa H, Ishikawa A, Kuwai T, Oka S., DDW 2025, 2025/05/03, Without Invitation, English
  7. COMPARISON OF NON-HELICOBACTER PYLORI HELICOBACTER-INDUCED GASTRIC MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA WITH A NODULAR GASTRITIS-LIKE APPEARANCE AND HELICOBACTER PYLORI-INDUCED CONVENTIONAL NODULAR GASTRITIS, Yuki Kitadai, Hidehiko Takigawa, Daisuke Shimizu, Misa Ariyoshi, Akiyoshi Tsuboi, Hidenori Tanaka, Ken Yamashita, Yuichi Hiyama, Yoshihiro Kishida, Yuji Urabe, Akira Ishikawa, Toshio Kuwai, Shiro Oka, DDW 2025, 2025/05/03, Without Invitation, English
  8. Clinical Usefulness and Acceptability of Small-bowel Capsule Endoscopy with Panoramic Imaging Compared with Axial Imaging, Hirata I, Tsuboi A, Shigenobu S, Matsubara Y, Takasago T, Nishimura T, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Urabe Y, Kuwai T, Oka S., APDW 2024, 2024/11/21, Without Invitation, English
  9. Clinical Usefulness and Acceptability of Small-bowel Capsule Endoscopy with Panoramic Imaging Compared with Axial Imaging, Hirata I, Tsuboi A, Shigenobu S, Matsubara Y, Takasago T, Nishimura T, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Urabe Y, Kuwai T, Oka S., JDDW 2024, 2024/10/31, Without Invitation, English
  10. Anti-tumor effect of Wee1 inhibitor AZD1775 on colorectal cancer., Ariyoshi M, Takigawa H, Kitadai Y, Shimizu D, Miyamoto R, Hiyama Y, Urabe Y, Oka S, , ,., UEGW 2024, 2024/10/12, Without Invitation, English
  11. Utility of cancer genome analysis using biopsy tissues from colorectal neoplasias developing from ulcerative colitis mucosa, Yamamoto N, Urabe Y, Takasago T, Ishikawa A, Tsuboi A, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Kuwai T, Arihiro K, Simamoto F, Oka S., UEGW 2024, 2024/10/12, Without Invitation, English
  12. Clinical utility and safety profile of endoscopic ischemic polypectomy for small-bowel polyps with Peutz-Jeghers syndrome compared with those of conventional polypectomy, Shigenobu S, Tsuboi A, Matsubara Y, Hirata I, Takasago T, Tanaka H, Yamashita K, Takigawa H, Urabe Y, Arihiro K, Oka S., ENDO 2024, 2024/07/04, Without Invitation, English
  13. Effect of operator's experience on delayed bleeding after colorectal EMR, Hamada T, Yamashita K, Saino M, Miyahara M, Takehara Y, Morimoto S, Yamamoto N, Tanino F, Kamigaichi Y, Takasago T, Tsuboi A, Tanaka H, Hiyama Y, Takigawa H, Kotachi T, Yuge R, Urabe Y, Oka S., ENDO 2024, 2024/07/04, Without Invitation, English
  14. Safety of balloon-assisted enteroscopy for patients taking antithrombotic medications, Hirata I, Tsuboi A, Shigenobu S, Matsubara Y, Takasago T, Nishimura T, Tanaka H, Yamashita K, Hiyama Y, Takigawa H, Urabe Y, Kuwai T, Oka S., 2024/05/30, Without Invitation, English
  15. Predictive factors of portal hypertensive enteropathy exacerbations based on long-term outcomes using capsule endoscopic findings, Matsubara Y, Tsuboi A, Shigenobu S, Hirata I, Takasago T, Tanaka H, Yamashita K, Takigawa H, Urabe Y, Oka S,., DDW 2024, 2024/05/18, Without Invitation, English
  16. LONG-TERM PROGNOSIS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION FOR ESOPHAGEAL CANCER IN ELDERLY PATIENTS, Konishi H, Urabe Y, Nakamura T, Ishibashi K, Mizuno J, Fukuhara M, Tanaka H, Tsuboi A, Yamashita K, Hiyama Y, Takigawa H, Oka S., DDW 2024, 2024/05/18, Without Invitation, English
  17. Comparison of outcomes between endoscopic submucosal dissection and Endoscopic laryngo-pharyngeal surgery for superficial laryngo-pharyngeal cancer, Urabe Y, Fukuhara M, Nakamura T, Ishibashi K, Konishi H, Mizuno J, Tanaka H, Tsuboi A, Yamashita K, Hiyama Y, Takigawa H, Kotachi T, Yuge R, Ueda T, Takeno S, Oka S., DDW 2024, 2024/05/18, Without Invitation, English
  18. LONG-TERM OUTCOMES OF PATIENTS WITH OBSCURE GASTROINTESTINAL BLEEDING AFTER NEGATIVE CAPSULE ENDOSCOPY​​​​, Hirata I, Tsuboi A, Matsubara Y, Sumioka A, Takasago T, Tanaka H, Yamashita K, Takigawa H, Kotachi T, Yuge R, Urabe Y, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  19. CLINICAL FEATURES AND PROGNOSIS OF SPORADIC NEOPLASIAS DETECTED IN ULCERATIVE COLITIS PATIENTS, Yamamoto N, Yamashita K, Takehara Y, Morimoto S, Tanino F, Kamigaichi Y, Tanaka H, Takigawa H, Yuge R, Urabe Y, Shimamoto F, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  20. OUTCOMES OF ESD IN EARLY GASTRIC CANCER PATIENTS WITH ADVANCED MALIGNANT TUMORS OF OTHER ORGANS, Takemoto H, Kotachi T, Teshima H, Tamari H, Tsuboi A, Tanaka H, Yamashita K, Takigawa H, Yuge R, Urabe Y, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  21. FOXP3+ T-CELLS AS PREDICTORS OF LYMPH NODE METASTASIS IN T1B COLORECTAL CANCER, Tamari H, Kitadai Y, Tanaka H, Tsuboi A, Yamashita K, Kotachi T, Takigawa H, Yuge R, Urabe Y, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  22. EVALUATION FOR DISEASE SURVEILLANCE OF PRIMARY SMALL-BOWEL FOLLICULAR LYMPHOMA IN CAPSULE ENDOSCOPY IMAGES BASED ON A DEEp CONVOLUTIONAL NEURAL NETWORK: A PILOT STUDY, Sumioka A, Tsuboi A, Matsubara Y, Hirata I, Takigawa H, Yuge R, Tada T, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  23. EFFECTS OF THE NEWLY DEVELOPED LARGE NEUTRAL AMINO ACID TRANSPORTER1 INHIBITOR, JPH203 ON TUMOR MICROENVIRONMENT IN COLORECTAL CANCER, Otani R, Takigawa H, Ariyoshi M, Shimizu D, Miyamoto R, Hiyama Y, Yuge R, Urabe Y, Ishikawa A, Kitadai Y, Oka S, 31th United European Gastroenterology Week (UEGW) 2023, 2023/10/12, Without Invitation, Japanese
  24. Clinicopathological features of metachronous gastric cancer after eradication, Teshima H, Kotachi T, Oka S, Takemoto H, Tamari H, Tanaka H, Tsuboi A, Hiyama Y, Yamashita K, Takigawa H, Yuge R, Hayashi R, Urabe Y, Oue N, Tanaka S, International Gastric Cancer Congress (IGCC) 2023, 2023/06/14, Without Invitation, Japanese
  25. CLINICOPATHOLOGICAL CHARACTERISTICS OF EARLY GASTRIC CANCER DISCOVERED AFTER HELICOBACTER PYLORI ERADICATION IN RELATION TO THE PERIOD AFTER ERADICATION AND HISTOLOGICAL TYPE, Teshima H, Kotachi T, Oka S, Mizuno J, Tamari H, Fukuhara M, Abudwaili M, Tanaka H, Tsuboi A, Yamashita K, Takigawa H, Yuge R, Hayashi R, Urabe Y, Ito M, Kitadai Y, Arihiro K, Tanaka S., American Society for Gastrointestinal Endoscopy (ASGE), DDW2022, 2022/05/21, Without Invitation, Japanese
  26. INDICATIONS OF A DENTAL FLOSS CLIP TRACTION DURING GASTRIC ENDOSCOPIC SUBMUCOSAL DISSECTION PERFORMED BY LESS-EXPERIENCED ENDOSCOPISTS, Tamari H, Oka S, Kotachi T, Teshima H, Tanaka H, Tsuboi A, Yamashita K, Takigawa H, Yuge R, Urabe Y, Tanaka S., American Society for Gastrointestinal Endoscopy (ASGE), DDW2022, 2022/05/21, Without Invitation, Japanese
  27. Evaluation of therapeutic efficacy of primary small-bowel follicular lymphoma using artificial intelligence system of capsule endoscopy: a pilot study, Sumioka A, Oka S, Tsuboi A, Hirata I, Iio S, Takigawa H, Yuge R, Tada T, Tanaka S., ENDO2022 (The 3rd World Congress of GI Endoscopy), 2022/05/13, Without Invitation, Japanese
  28. Efficacy of scissor type knife specialized for gastric endoscopic submucosal dissection, Tamari H, Oka S, Kotachi T, Teshima H, Tanaka H, Tsuboi A, Yamashita K, Takigawa H, Yuge R, Urabe Y, Arihiro K, Tanaka S., ENDO2022 (The 3rd World Congress of GI Endoscopy), 2022/05/13, Without Invitation, Japanese
  29. Predictive factors for esophageal stenosis in patients with the preventive administered steroids after endoscopic submucosal resection for esophageal squamous cell carcinoma, Mizuno J, Urabe Y, Oka S, Fukuhara M, Tanaka H, Tsuboi A, Yamashita K, Hiyama Y, Kotachi T, Takigawa H, Yuge R, Hayashi R, Tanaka S., ENDO2022 (The 3rd World Congress of GI Endoscopy), 2022/05/13, Without Invitation, Japanese
  30. Outcomes of Endoscopic Polidocanol Injection Therapy for Small-bowel Angioectasia in Systemic Sclerosis Patients, Iio S, Oka S, Sumioka A, Tsuboi A, Hiyama Y, Yamashita K, Kotachi T, Takigawa H, Yuge R, Urabe Y, Tanaka S., Asian Pacific Digestive Week (APDW) 2021, 2021/08/19, Without Invitation, English
  31. Expression of SPARC is associated with poor prognosis in human colorectal cancer, Toshikatsu Naito, Yasuhiko Kitadai, Hidehiko Takigawa, Ryo Yuge, Toshio Kuwai, Wataru Yasui, Shinji Tanaka, Kazuaki Chayama, Annual meeting of the Japanese Cancer Association, Without Invitation, Japanese

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Early-Career Scientists), Evaluation of anti-tumor effects of oral antidiabetic agent, SGLT inhibitors focusing on SGLT1/2 inhibition profiles., 2024/04/01, 2027/03/31
  2. Nozomi H Foundation, subsidy for the promotion of cancer treatment research, Exploring the potential of oral diabetic drugs, SGLT family inhibitors, as anti-tumor agents, 2023/02/01, 2025/01/31
  3. KAKENHI(Grant-in-Aid for Early-Career Scientists), Evaluation of the efficacy of LAT1 inhibitor to tumor stroma and immunity in an allogenic mouse model of colon cancer having abundant stroma., 2021/04/01, 2024/03/31
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  4. Ryokufukai Research Grant, Research on LAT1 Expression in Colorectal Cancer and Its Potential as a Therapeutic Target, 2020/04/01, 2021/03/31

Social Activities

History as Peer Reviews of Academic Papers

  1. 2026, Internal Medicine, Others, reviewer, 3
  2. 2026, Cancer Cell International, Others, reviewer, 1
  3. 2026, Therapeutic Advances in Gastroenterology, Others, reviewer, 1
  4. 2025, DEN open, Others, reviewer, 1
  5. 2025, BMC Cancer, Others, reviewer, 1
  6. 2025, Endoscopy International Open, Others, reviewer, 1
  7. 2025, Cancer Medicine, Others, reviewer, 4
  8. 2025, Internal Medicine, Others, reviewer, 8
  9. 2025, Journal of the Anus, Rectum and Colon, Others, reviewer, 1
  10. 2025, Plos One, Others, reviewer, 3
  11. 2025, The New England Journal of Medicine, Others, reviewer, 1
  12. 2025, Gastric Cancer, Others, reviewer, 2
  13. 2024, Cancer Science, Others, reviewer, 2
  14. 2024, Gastric Cancer, Others, reviewer, 1
  15. 2024, Cancer Medicine, Others, reviewer, 3
  16. 2023, Heliyon, Others, reviewer, 1
  17. 2023, Journal of Cancer Research and Clinical Oncology, Others, reviewer, 1
  18. 2023, Cancer Cell International, Others, reviewer, 1
  19. 2023, Cancer Medicine, Others, reviewer, 2
  20. 2023, Cancers, Others, reviewer, 2
  21. 2023, Diagnostics, Others, reviewer, 2
  22. 2023, International Journal of Molecular Sciences, Others, reviewer, 2
  23. 2022, Internal Medicine, Others, reviewer, 1
  24. 2022, Diagnostics, Others, reviewer, 2
  25. 2022, Cancers, Others, reviewer, 5
  26. 2021, International Journal of Hematology, Others, reviewer, 1