NAOKI ISHIUCHI

Last Updated :2025/06/04

Affiliations, Positions
Health Service Center, Assistant Professor
E-mail
ishiuchihiroshima-u.ac.jp

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical & Health Sciences, Japan, 2016/04, 2020/05
  • Hiroshima University, School of Medicine, Japan, 2005/04, 2011/03

Academic Degrees

  • Hiroshima University

Affiliated Academic Societies

  • The Japanese Society of Internal Medicine
  • Japanese Society of Nephrology
  • The Japanese Society for Dialysis Therapy
  • Japanese Society for Peritoneal Dialysis
  • The Japanese Society for Regenerative Medicine

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 3Term, Introduction to Student Wellness
  2. 2025, Undergraduate Education, 3Term, Family Nursing
  3. 2025, Undergraduate Education, Year, Clinical diagnosis and treatment I

Research Activities

Academic Papers

  1. Renal protective effects of extracellular vesicle-encapsulated tumor necrosis factor-alpha-induced protein 6 derived from mesenchymal stem cells, Stem Cells, 43(5), 20250515
    Link to Paper Search Results by DOI
  2. Effect of Haemodiafiltration Versus Haemodialysis on Vascular Access Patency in Patients, Nephrol Dial Transplant, in press, 2025
  3. Targeting MLL1/WDR5-Mediated Epigenetic Regulation Mitigates Peritoneal Fibrosis by Reducing p16INK4a, FASEB J, 39, e70543, 20250430
    Link to Paper Search Results by DOI
  4. Peritoneal dialysis-associated polymicrobial peritonitis with slow onset after root canal treatment: the first case and review of the literature, BMC NEPHROLOGY, 26(1), 20250313
    Link to Paper Search Results by DOI
  5. Successful treatment of severe renal failure caused by malignant hypertension using a combination of renin-angiotensin-aldosterone system inhibitors: a case report., CEN Case Rep, 14, 200-207, 20250414
    Link to Paper Search Results by DOI
  6. Peritoneal dialysis-associated peritonitis, caused by superior mesenteric artery thrombosis with intestinal necrosis: a case report., CEN Case Rep, 14, 1-5, 20250214
    Link to Paper Search Results by DOI
  7. Selective activation of PPARα by pemafibrate mitigates peritoneal inflammation and fibrosis through suppression of NLRP3 inflammasome and modulation of inflammation, SCIENTIFIC REPORTS, 14(1), 20241011
    Link to Paper Search Results by DOI
  8. Impact of immunosuppressive drugs on efficacy of mesenchymal stem cell therapy for suppressing renal fibrosis, STEM CELLS TRANSLATIONAL MEDICINE, 13(11), 1067-1085, 20241014
    Link to Paper Search Results by DOI
  9. Comparison between the 0- and 30-second balloon dilation time in percutaneous transluminal Angioplasty for Restenosed arteriovenous fistula among hemodialysis Patients: A multicenter, prospective, randomized trial (CARP study), Clin Exp Nephrol, 28, 647-655, 202407
    Link to Paper Search Results by DOI
  10. Mesenchymal stem cells pretreated with interferon-gamma attenuate renal fibrosis by enhancing regulatory T cell induction, SCIENTIFIC REPORTS, 14(1), 20240504
    Link to Paper Search Results by DOI
  11. Adipose-derived mesenchymal stem cells cultured in serum-free medium attenuate acute contrast-induced nephropathy by exerting anti-apoptotic effects, STEM CELL RESEARCH & THERAPY, 14(1), 337, 20231122
    Link to Paper Search Results by DOI
  12. Comparison of the Therapeutic Effects of Adipose- and Bone Marrow-Derived Mesenchymal Stem Cells on Renal Fibrosis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(23), 202312
    Link to Paper Search Results by DOI
  13. ★, Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissues, STEM CELL RESEARCH & THERAPY, 14(1), 20230504
    Link to Paper Search Results by DOI
  14. Age estimation using post-mortem computed tomography and fetal dental radiographic findings in an early to mid-pregnancy fetus: A case report, LEGAL MEDICINE, 62, 202305
    Link to Paper Search Results by DOI
  15. Comparison of survival rates between incident hemodialysis patients and peritoneal dialysis patients: a 5-year prospective cohort study with propensity score matching, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 27(5), 419-426, 202305
    Link to Paper Search Results by DOI
  16. Four cases of cytokine storm after COVID-19 vaccination: Case report, FRONTIERS IN IMMUNOLOGY, 20220815
    Link to Paper Search Results by DOI
  17. A method for determining valproic acid in human whole blood and urine via gas chromatography-mass spectrometry and small-scale inter-laboratory trial, LEGAL MEDICINE, 202211
    Link to Paper Search Results by DOI
  18. Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis, STEM CELLS INTERNATIONAL, 20220320
    Link to Paper Search Results by DOI
  19. The hypoxia-inducible factor-alpha prolyl hydroxylase inhibitor FG4592 ameliorates renal fibrosis by inducing the H3K9 demethylase JMJD1A, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 323(5), F539-F552, 202211
    Link to Paper Search Results by DOI
  20. Interferon-gamma enhances the therapeutic effect of mesenchymal stem cells on experimental renal fibrosis, SCIENTIFIC REPORTS, 20210113
    Link to Paper Search Results by DOI
  21. Mesenchymal stem cells cultured in serum-free medium ameliorate experimental peritoneal fibrosis, STEM CELL RESEARCH & THERAPY, 203, 20210323
    Link to Paper Search Results by DOI
  22. Localization and Maintenance of Engrafted Mesenchymal Stem Cells Administered via Renal Artery in Kidneys with Ischemia-Reperfusion Injury, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 202104
    Link to Paper Search Results by DOI
  23. ★, Serum-free medium and hypoxic preconditioning synergistically enhance the therapeutic effects of mesenchymal stem cells on experimental renal fibrosis, STEM CELL RESEARCH & THERAPY, 20210823
    Link to Paper Search Results by DOI
  24. Lower Geriatric Nutritional Risk Index (GNRI) Is Associated with Higher Risk of Fractures in Patients Undergoing Hemodialysis, NUTRIENTS, 202108
    Link to Paper Search Results by DOI
  25. ★, Hypoxia-preconditioned mesenchymal stem cells prevent renal fibrosis and inflammation in ischemia reperfusion rats., Stem Cell Res Ther, 130, 2020

Invited Lecture, Oral Presentation, Poster Presentation

  1. Mesenchymal stem cells, Keisuke Morimoto, Ayumu Nakashima, Naoki Ishiuchi, Kisho Miyasako, Yoshiki Tanaka, Kensuke Sasaki, Takao Masaki:, The 57th American Society of Nephrology, 2024, Without Invitation, English, San Diego, USA
  2. Thrombomodulin overexpressing adipose-derived mesenchymal stem cells prevent thromboembolism and ameliorate renal fibrosis in rats., Yoshiki Tanaka, Ayumu Nakashima, Naoki Ishiuchi, Kisho Miyasako, Keisuke Morimoto, Kensuke Sasaki, Takao Masaki, The 57th American Society of Nephrology, 2024, Without Invitation, English, San Diego, USA
  3. Comparison of therapeutic effects of adipose-derived and bone marrow mesenchymal stem cells on renal fibrosis, Maria Yoshida, Ayumu Nakashima, Naoki Ishiuchi, Kisho Miyasako, Yoshiki Tanaka, Keisuke Morimoto, Kensuke Sasaki, Takao Masaki, The 56th American Society of Nephrology, 2023, Without Invitation, English, Philadelphia, USA
  4. Mesenchymal stem cells pretreated with interferon-gamma attenuate renal fibrosis by enhancing regulatory T cell induction, So Kurawaki, Ayumu Nakashima, Naoki Ishiuchi, Ryo Kanai, Kensuke Sasaki, Takao Masaki, The 56th American Society of Nephrology, 2023, Without Invitation, English, Philadelphia, USA
  5. Magnesium protects against CKD progression by reducing DNA damage, Makoto Matsubara, Kensuke Sasaki, Naoki Ishiuchi, Akira Takahashi, Yosuke Osaki, Yujiro Maeoka, Takao Masaki, The 56th American Society of Nephrology, 2023, Without Invitation, English, Philadelphia, USA
  6. PPARa modulator ameliorates methylglyoxal-induced peritoneal fibrosis, Yutaka Shinkai, Ryo Tamura, Naoki Ishiuchi, Yosuke Osaki, Yujiro Maeoka, Kensuke Sasaki, Takao Masaki, The 56th American Society of Nephrology, 2023, Without Invitation, English, Philadelphia, USA
  7. Adipose-Derived Mesenchymal Stem Cells Cultured in Serum-Free Medium Attenuate Acute Contrast-Induced Nephropathy by Exerting Anti-Apoptotic Effects, Mitsuki Kadono, Naoki Ishiuchi, Ayumu Nakashima, Kensuke Sasaki, and Takao Masaki, The 55th American Society of Nephrology, 2022, Without Invitation, English, Orlando, USA
  8. Mesenchymal stem cells cultured in serum-free medium ameliorate experimental peritoneal fibrosis, Ryo Tamura, Ayumu Nakashima, Kohei Nagasaki, Toshinori Ueno, Naoki Ishiuchi, Toshiki Doi, Shigehiro Doi,Yukio Kato, and Takao Masaki, The 9th Asia Pacific Chapter Meeting of International Society for Peritoneal Dialysis, 2019, Without Invitation, Nagoya, Japan
  9. Mesenchymal stem cells cultured in IFN-gamma-containing medium ameliorate experimental renal fibrosis, Ryo Kanai, Ayumu Nakashima, Shigenori Doi, Tomoe Kimura, Ken Yosida, Naoki Ishiuchi, Yumi Yamada, Toshiki Doi,Yukio Kato, and Takao Masaki, The 52th American Society of Nephrology, 2019, Without Invitation, Washington DC, USA
  10. Hypoxia-preconditioned mesenchymal stem cells prevent AKI to CKD progression, Naoki Ishiuchi, Ayumu Nakashima, Shigehiro Doi, Ken Yoshida, Satoshi Maeda, Ryo Kanai, Yumi Yamada, Toshiki Doi, Yukio Kato, and Takao Masaki, The 52th American Society of Nephrology, 2019, Without Invitation, Washington DC, USA

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2024, 2025
  2. KAKENHI, 2023, 2026
  3. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2022, 2023
  4. 2021, 2024

Social Activities

History as Peer Reviews of Academic Papers

  1. 2025, Internal Medicine, Others, 2
  2. 2025, Scientific Reports, Others, 2
  3. 2024, Cell Comunication and Signaling, Others, 1