ATSUO YOSHINO

Last Updated :2025/04/03

Affiliations, Positions
Health Service Center, Associate Professor
E-mail
yoshinohiroshima-u.ac.jp
Self-introduction
I have been studying pain from the view of psychiatry and neuroimaging. I have been also treating chronic pain by psychosocial approach such as cognitive behavioral therapy.

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Medicine, Japan, 2006/04, 2010/03
  • Hiroshima University, Faculty of Medicine, Japan, 1996/04, 2002/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Psychiatric science

Research Keywords

  • Neuroimaging
  • Chronic pain
  • Cognitive behavioral therapy

Affiliated Academic Societies

  • Sigma Xi
  • Society for Neuroscience
  • World Federation of Societies of Biological Psychiatry
  • International Association for the Study of Pain

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 3Term, Introduction to Student Wellness
  2. 2025, Undergraduate Education, Intensive, Practice of Medicine I

Research Activities

Academic Papers

  1. Clinical effects of online cognitive behavioral group therapy for chronic pain patients and developing a therapeutic alliance: A pre–post pilot trial, HEALTH SCIENCE REPORTS, 7, e2141, 20240501
  2. Changes in Resting-State Brain Activity After Cognitive Behavioral Therapy for Chronic Pain: A Magnetoencephalography Study, JOURNAL OF PAIN, 20240404
  3. A Case of a Father and Son With Complex Regional Pain Syndrome Type 1 Exhibiting Different Resting-State Functional Connectivity on Functional MRI, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(1), 20240119
    Link to Paper Search Results by DOI
  4. Verification of the brain network marker of major depressive disorder: Test-retest reliability and anterograde generalization performance for newly acquired data, JOURNAL OF AFFECTIVE DISORDERS, 326, 262-266, 20230401
    Link to Paper Search Results by DOI
  5. Interoceptive accuracy is related to the psychological mechanisms of the burning mouth syndrome: a cross-sectional study, BMC ORAL HEALTH, 22(1), 20220719
    Link to Paper Search Results by DOI
  6. Left DLPFC activity is associated with plasma kynurenine levels and can predict treatment response to escitalopram in major depressive disorder, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 76(8), 367-376, 202208
    Link to Paper Search Results by DOI
  7. Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 75(2), 46-56, 202102
    Link to Paper Search Results by DOI
  8. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation, JOURNAL OF AFFECTIVE DISORDERS, 279, 20-30, 20210115
    Link to Paper Search Results by DOI
  9. Peripheral arterial stiffness during electrocutaneous stimulation is positively correlated with pain-related brain activity and subjective pain intensity: an fMRI study, SCIENTIFIC REPORTS, 11(1), 20210224
    Link to Paper Search Results by DOI
  10. Cardiorespiratory synchronisation and systolic blood pressure correlation of peripheral arterial stiffness during endoscopic thoracic sympathectomy, Scientific Reports, 11, 5966, 2021
  11. Peripheral arterial stiffness during electrocutaneous stimulation is positively correlated with pain-related brain activity and subjective pain intensity: an fMRI study, Scientific Reports, 11, 4425, 2021
  12. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation, Journal of Affective Disorders, 279, 20-30, 2021
  13. Pain-related beliefs, cognitive processes, and electroencephalography band power as predictors and mediators of the effects of psychological chronic pain interventions, Pain, 162, 2036-2050, 2021
  14. Brain changes associated with impaired attention function in chronic pain, Brain and Cognition, in press, 2021
  15. Resting-state brain activity can predict target-independent aptitude in fMRI-neurofeedback training, NEUROIMAGE, 245, 20211215
    Link to Paper Search Results by DOI
  16. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation., Journal of affective disorders, 279, 2021
  17. Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls., Psychiatry and clinical neurosciences, 75(2), 2021
  18. Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report, JOURNAL OF AFFECTIVE DISORDERS, 271, 224-227, 2020
  19. Importance of the Habenula for Avoidance Learning Including Contextual Cues in the Human Brain: A Preliminary fMRI Study, FRONTIERS IN HUMAN NEUROSCIENCE, 14, 2020
  20. Neuroimaging studies about the relationship between negative emotions and pain, PAIN RESEARCH, 35(1), 17-23, 2020
    Link to Paper Search Results by DOI
  21. Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome analysis, SCIENTIFIC REPORTS, 10(1), 20201008
    Link to Paper Search Results by DOI
  22. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis, JOURNAL OF PAIN RESEARCH, 13, 3227-3234, 2020
    Link to Paper Search Results by DOI
  23. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder, BRAIN AND BEHAVIOR, 10(12), 202012
    Link to Paper Search Results by DOI
  24. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder, Brain and Behavior, 10, e1868, 2020
  25. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis, Journal of Pain Research, 13, 3227-3234, 2020
  26. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder., Brain and behavior, 10(12), 2020
  27. Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report., Journal of affective disorders, 271, 2020
  28. Importance of the Habenula for Avoidance Learning Including Contextual Cues in the Human Brain: A Preliminary fMRI Study., Frontiers in human neuroscience, 14, 2020
  29. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis., Journal of pain research, 13, 2020
  30. Role of coping with negative emotions in cognitive behavioral therapy for persistent somatoform pain disorder: Is it more important than pain catastrophizing?, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 73(9), 560-565, 2019
  31. Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest, FRONTIERS IN HUMAN NEUROSCIENCE, 13, 2019
  32. Role of coping with negative emotions in cognitive behavioral therapy for persistent somatoform pain disorder: Is it more important than pain catastrophizing?, Psychiatry and clinical neurosciences, 73(9), 2019
  33. Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest., Frontiers in human neuroscience, 13, 2019
  34. Quantitative Evaluation of Pain during Electrocutaneous Stimulation using a Log-Linearized Peripheral Arterial Viscoelastic Model, SCIENTIFIC REPORTS, 8, 20180215
    Link to Paper Search Results by DOI
  35. Changes in resting-state brain networks after cognitive-behavioral therapy for chronic pain, PSYCHOLOGICAL MEDICINE, 48(7), 1148-1156, 201805
    Link to Paper Search Results by DOI
  36. Effects of behavioural activation on the neural circuit related to intrinsic motivation, BJPSYCH OPEN, 4(5), 317-323, 201809
    Link to Paper Search Results by DOI
  37. Effects of behavioral activation program without psychotropic medication treatment for depression in late adolescence: case report, NEUROPSYCHIATRIC DISEASE AND TREATMENT, 14, 2159-2164, 2018
    Link to Paper Search Results by DOI
  38. Effects of behavioural activation on the neural circuit related to intrinsic motivation, BJPSYCH OPEN, 4(5), 317-323, 2018
  39. Effects of behavioral activation program without psychotropic medication treatment for depression in late adolescence: case report., Neuropsychiatric disease and treatment, 14, 2018
  40. Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices, JOURNAL OF AFFECTIVE DISORDERS, 208, 610-614, 20170115
    Link to Paper Search Results by DOI
  41. Regional brain functions in the resting state indicative of potential differences between depression and chronic pain, SCIENTIFIC REPORTS, 7, 20170617
    Link to Paper Search Results by DOI
  42. Functional alterations of Postcentral gyrus Modulated by angry Facial expressions during intraoral Tactile stimuli in Patients with Burning Mouth syndrome: a Functional Magnetic resonance imaging study, FRONTIERS IN PSYCHIATRY, 8, 20171106
    Link to Paper Search Results by DOI
  43. Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices, JOURNAL OF AFFECTIVE DISORDERS, 208, 610-614, 2017
  44. Regional brain functions in the resting state indicative of potential differences between depression and chronic pain, SCIENTIFIC REPORTS, 7, 2017
  45. Functional alterations of Postcentral gyrus Modulated by angry Facial expressions during intraoral Tactile stimuli in Patients with Burning Mouth syndrome: a Functional Magnetic resonance imaging study, FRONTIERS IN PSYCHIATRY, 8, 2017
  46. fMRI Study of Social Anxiety during Social Ostracism with and without Emotional Support, PLOS ONE, 10(5), 20150522
    Link to Paper Search Results by DOI
  47. Do Individuals with Alcohol Dependence Show Higher Unfairness Sensitivity? The Relationship Between Impulsivity and Unfairness Sensitivity in Alcohol-Dependent Adults, ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 39(10), 2016-2021, 201510
    Link to Paper Search Results by DOI
  48. Effectiveness of group cognitive behavioral therapy for somatoform pain disorder patients in Japan: A preliminary non-case-control study, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 69(12), 763-772, 201512
    Link to Paper Search Results by DOI
  49. Neural Basis of Anticipatory Anxiety Reappraisals, PLOS ONE, 9(7), 2014
  50. ★, Distinctive spontaneous regional neural activity in patients with somatoform pain disorder: A preliminary resting-state fMRI study, PSYCHIATRY RESEARCH-NEUROIMAGING, 221(3), 246-248, 20140330
    Link to Paper Search Results by DOI
  51. Psychosocial functioning is correlated with activation in the anterior cingulate cortex and left lateral prefrontal cortex during a verbal fluency task in euthymic bipolar disorder: A preliminary fMRI study, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 68(3), 188-196, 201403
    Link to Paper Search Results by DOI
  52. Visual imagery while reading concrete and abstract Japanese kanji words: An fMRI study, NEUROSCIENCE RESEARCH, 79, 61-66, 201402
    Link to Paper Search Results by DOI
  53. Cognitive behavioral therapy for depression changes medial prefrontal and ventral anterior cingulate cortex activity associated with self-referential processing, SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 9(4), 487-493, 201404
    Link to Paper Search Results by DOI
  54. The dorsolateral prefrontal network is involved in pain perception in knee osteoarthritis patients, NEUROSCIENCE LETTERS, 581, 109-114, 2014
  55. ★, Distinctive neural responses to pain stimuli during induced sadness in patients with somatoform pain disorder: An fMRI study, NEUROIMAGE-CLINICAL, 2, 782-789, 2013
    Link to Paper Search Results by DOI
  56. ★, Sadness Enhances the Experience of Pain and Affects Pain-Evoked Cortical Activities: An MEG Study, JOURNAL OF PAIN, 13(7), 628-635, 201207
    Link to Paper Search Results by DOI
  57. F-MRI analysis using self-referential negative emotion task on the effect of cognitive behavioral therapy for depressive patients, NEUROSCIENCE RESEARCH, 71, E210-E210, 2011
  58. Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy, BMC PSYCHIATRY, 10, 20100316
    Link to Paper Search Results by DOI
  59. ★, Sadness enhances the experience of pain via neural activation in the anterior cingulate cortex and amygdala: An fMRI study, NEUROIMAGE, 50(3), 1194-1201, 2010

Publications such as books

  1. 2017, Neuroimaging of Pain, Neuroimaging studies of somatoform pain disorder: How far have we come?, Springer, 2017, Scholarly Book, Joint work, English, Atsuo Yoshino, Yasumasa Okamoto, Shigeto Yamawaki

Invited Lecture, Oral Presentation, Poster Presentation

  1. Changes in resting-state functional connectivity after cognitive behavioral therapy for chronic pain, Yoshino A, Okamoto Y, Okada G, Yokoyama S, Jinnin R, Takamura M, Ichikawa N and Yamawaki S, Neuroscience 2018, 2018/11/05, Without Invitation, English
  2. Similarities and differences of spontaneous neural activity in patients with chronic pain and depression: A resting state fMRI study, Atsuo Yoshino, Yasumasa Okamoto, Naofumi Otsuru, Go Okada, Shigeto Yamawaki, 16th World Congress on Pain, 2016, Without Invitation, English
  3. Distinctive spontaneous neural activity in patients with somatoform pain disorder: A resting state fMRI study, Yoshino Atuo, Yamawaki Shigeto, The International College of Neuropsychopharmacology, 2014/06/22, Without Invitation, English
  4. Neural responses to low-pain stimuli during sadness in patients with somatoform pain disorder: An fMRI study, World Congress of Biological Psychiatry, 2013, Without Invitation
  5. Sadness enhances the experience of pain and affects brain regions associated with pain, The International College of Neuropsychopharmacology, 2012, Without Invitation
  6. Emotional regulation of cortical activations evoked by pain perception – an MEG study–, Society for Neuroscience, 2008, Without Invitation
  7. Usefulness of spatial filter on the pain perception: an MEG study., International Society for the Advancement of Clinical Magnetoencephalography, 2006, Without Invitation

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2018, 2021
  2. KAKENHI, 2015, 2017
    Permalink
  3. KAKENHI, 2015, 2018
  4. KAKENHI, 2012, 2014
    Permalink

Social Activities

History as Peer Reviews of Academic Papers

  1. 2020, Journal of Pain Research
  2. 2020, Journal of Affective Disorders
  3. 2020, Frontiers in Human Neuroscience
  4. 2019, Frontiers in Psychology
  5. 2019, Frontiers in Neuroscience
  6. 2019, Brain and Behavior
  7. 2019, Biopsychosocial Medicine
  8. 2018, Scientific Reports
  9. 2018, Brain Imaging and Behavior
  10. 2017, Neuropsychiatry
  11. 2017, Journal of Neuroimaging
  12. 2016, Scientific Reports
  13. 2016, PlosOne
  14. 2016, Journal of International Medical Research
  15. 2016, Brain and Behavior, Others
  16. 2015, Psychology & Psychotherapy, 1
  17. 2015, Psychiatry and Clinical Neuroscience, 1
  18. 2015, The Tohoku Journal of Experimental Medicine, 1
  19. 2014, Clinical Neurophysiology, 1