ATSUO YOSHINO

Last Updated :2024/04/03

Affiliations, Positions
Health Service Center, Associate Professor
E-mail
yoshinohiroshima-u.ac.jp
Self-introduction
I have been studying pain from the view of psychiatry and neuroimaging. I have been also treating chronic pain by psychosocial approach such as cognitive behavioral therapy.

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Medicine, Japan, 2006/04, 2010/03
  • Hiroshima University, Faculty of Medicine, Japan, 1996/04, 2002/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Psychiatric science

Research Keywords

  • Neuroimaging
  • Chronic pain
  • Cognitive behavioral therapy

Affiliated Academic Societies

  • Sigma Xi
  • Society for Neuroscience
  • World Federation of Societies of Biological Psychiatry
  • International Association for the Study of Pain

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 3Term, Introduction to Student Wellness
  2. 2024, Undergraduate Education, Intensive, Practice of Medicine I

Research Activities

Academic Papers

  1. Verification of the brain network marker of major depressive disorder: Test-retest reliability and anterograde generalization performance for newly acquired data, JOURNAL OF AFFECTIVE DISORDERS, 326, 262-266, 20230401
  2. Interoceptive accuracy is related to the psychological mechanisms of the burning mouth syndrome: a cross-sectional study, BMC ORAL HEALTH, 22(1), 20220719
  3. Left DLPFC activity is associated with plasma kynurenine levels and can predict treatment response to escitalopram in major depressive disorder, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 76(8), 367-376, 202208
  4. Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 75(2), 46-56, 202102
  5. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation, JOURNAL OF AFFECTIVE DISORDERS, 279, 20-30, 20210115
  6. Peripheral arterial stiffness during electrocutaneous stimulation is positively correlated with pain-related brain activity and subjective pain intensity: an fMRI study, SCIENTIFIC REPORTS, 11(1), 20210224
  7. Cardiorespiratory synchronisation and systolic blood pressure correlation of peripheral arterial stiffness during endoscopic thoracic sympathectomy, Scientific Reports, 11, 5966, 2021
  8. Peripheral arterial stiffness during electrocutaneous stimulation is positively correlated with pain-related brain activity and subjective pain intensity: an fMRI study, Scientific Reports, 11, 4425, 2021
  9. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation, Journal of Affective Disorders, 279, 20-30, 2021
  10. Pain-related beliefs, cognitive processes, and electroencephalography band power as predictors and mediators of the effects of psychological chronic pain interventions, Pain, 162, 2036-2050, 2021
  11. Brain changes associated with impaired attention function in chronic pain, Brain and Cognition, in press, 2021
  12. Resting-state brain activity can predict target-independent aptitude in fMRI-neurofeedback training, NEUROIMAGE, 245, 20211215
  13. Personality classification enhances blood metabolome analysis and biotyping for major depressive disorders: two-species investigation., Journal of affective disorders, 279, 2021
  14. Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls., Psychiatry and clinical neurosciences, 75(2), 2021
  15. Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report, JOURNAL OF AFFECTIVE DISORDERS, 271, 224-227, 2020
  16. Importance of the Habenula for Avoidance Learning Including Contextual Cues in the Human Brain: A Preliminary fMRI Study, FRONTIERS IN HUMAN NEUROSCIENCE, 14, 2020
  17. Neuroimaging studies about the relationship between negative emotions and pain, PAIN RESEARCH, 35(1), 17-23, 2020
  18. Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome analysis, SCIENTIFIC REPORTS, 10(1), 20201008
  19. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis, JOURNAL OF PAIN RESEARCH, 13, 3227-3234, 2020
  20. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder, BRAIN AND BEHAVIOR, 10(12), 202012
  21. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder, Brain and Behavior, 10, e1868, 2020
  22. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis, Journal of Pain Research, 13, 3227-3234, 2020
  23. White matter abnormalities and cognitive function in euthymic patients with bipolar disorder and major depressive disorder., Brain and behavior, 10(12), 2020
  24. Antidepressive effect of left dorsolateral prefrontal cortex neurofeedback in patients with major depressive disorder: A preliminary report., Journal of affective disorders, 271, 2020
  25. Importance of the Habenula for Avoidance Learning Including Contextual Cues in the Human Brain: A Preliminary fMRI Study., Frontiers in human neuroscience, 14, 2020
  26. Altered Resting-State Connectivity with Pain-Related Expectation Regions in Female Patients with Severe Knee Osteoarthritis., Journal of pain research, 13, 2020
  27. Role of coping with negative emotions in cognitive behavioral therapy for persistent somatoform pain disorder: Is it more important than pain catastrophizing?, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 73(9), 560-565, 2019
  28. Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest, FRONTIERS IN HUMAN NEUROSCIENCE, 13, 2019
  29. Role of coping with negative emotions in cognitive behavioral therapy for persistent somatoform pain disorder: Is it more important than pain catastrophizing?, Psychiatry and clinical neurosciences, 73(9), 2019
  30. Predicting Ventral Striatal Activation During Reward Anticipation From Functional Connectivity at Rest., Frontiers in human neuroscience, 13, 2019
  31. Quantitative Evaluation of Pain during Electrocutaneous Stimulation using a Log-Linearized Peripheral Arterial Viscoelastic Model, SCIENTIFIC REPORTS, 8, 20180215
  32. Changes in resting-state brain networks after cognitive-behavioral therapy for chronic pain, PSYCHOLOGICAL MEDICINE, 48(7), 1148-1156, 201805
  33. Effects of behavioural activation on the neural circuit related to intrinsic motivation, BJPSYCH OPEN, 4(5), 317-323, 201809
  34. Effects of behavioral activation program without psychotropic medication treatment for depression in late adolescence: case report, NEUROPSYCHIATRIC DISEASE AND TREATMENT, 14, 2159-2164, 2018
  35. Effects of behavioural activation on the neural circuit related to intrinsic motivation, BJPSYCH OPEN, 4(5), 317-323, 2018
  36. Effects of behavioral activation program without psychotropic medication treatment for depression in late adolescence: case report., Neuropsychiatric disease and treatment, 14, 2018
  37. Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices, JOURNAL OF AFFECTIVE DISORDERS, 208, 610-614, 20170115
  38. Regional brain functions in the resting state indicative of potential differences between depression and chronic pain, SCIENTIFIC REPORTS, 7, 20170617
  39. Functional alterations of Postcentral gyrus Modulated by angry Facial expressions during intraoral Tactile stimuli in Patients with Burning Mouth syndrome: a Functional Magnetic resonance imaging study, FRONTIERS IN PSYCHIATRY, 8, 20171106
  40. Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices, JOURNAL OF AFFECTIVE DISORDERS, 208, 610-614, 2017
  41. Regional brain functions in the resting state indicative of potential differences between depression and chronic pain, SCIENTIFIC REPORTS, 7, 2017
  42. Functional alterations of Postcentral gyrus Modulated by angry Facial expressions during intraoral Tactile stimuli in Patients with Burning Mouth syndrome: a Functional Magnetic resonance imaging study, FRONTIERS IN PSYCHIATRY, 8, 2017
  43. fMRI Study of Social Anxiety during Social Ostracism with and without Emotional Support, PLOS ONE, 10(5), 20150522
  44. Do Individuals with Alcohol Dependence Show Higher Unfairness Sensitivity? The Relationship Between Impulsivity and Unfairness Sensitivity in Alcohol-Dependent Adults, ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 39(10), 2016-2021, 201510
  45. Effectiveness of group cognitive behavioral therapy for somatoform pain disorder patients in Japan: A preliminary non-case-control study, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 69(12), 763-772, 201512
  46. Neural Basis of Anticipatory Anxiety Reappraisals, PLOS ONE, 9(7), 2014
  47. ★, Distinctive spontaneous regional neural activity in patients with somatoform pain disorder: A preliminary resting-state fMRI study, PSYCHIATRY RESEARCH-NEUROIMAGING, 221(3), 246-248, 20140330
  48. Psychosocial functioning is correlated with activation in the anterior cingulate cortex and left lateral prefrontal cortex during a verbal fluency task in euthymic bipolar disorder: A preliminary fMRI study, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 68(3), 188-196, 201403
  49. Visual imagery while reading concrete and abstract Japanese kanji words: An fMRI study, NEUROSCIENCE RESEARCH, 79, 61-66, 201402
  50. Cognitive behavioral therapy for depression changes medial prefrontal and ventral anterior cingulate cortex activity associated with self-referential processing, SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 9(4), 487-493, 201404
  51. The dorsolateral prefrontal network is involved in pain perception in knee osteoarthritis patients, NEUROSCIENCE LETTERS, 581, 109-114, 2014
  52. ★, Distinctive neural responses to pain stimuli during induced sadness in patients with somatoform pain disorder: An fMRI study, NEUROIMAGE-CLINICAL, 2, 782-789, 2013
  53. ★, Sadness Enhances the Experience of Pain and Affects Pain-Evoked Cortical Activities: An MEG Study, JOURNAL OF PAIN, 13(7), 628-635, 201207
  54. F-MRI analysis using self-referential negative emotion task on the effect of cognitive behavioral therapy for depressive patients, NEUROSCIENCE RESEARCH, 71, E210-E210, 2011
  55. Psychosocial functioning in patients with treatment-resistant depression after group cognitive behavioral therapy, BMC PSYCHIATRY, 10, 20100316
  56. ★, Sadness enhances the experience of pain via neural activation in the anterior cingulate cortex and amygdala: An fMRI study, NEUROIMAGE, 50(3), 1194-1201, 2010

Publications such as books

  1. 2017, Neuroimaging of Pain, Neuroimaging studies of somatoform pain disorder: How far have we come?, Springer, 2017, Scholarly Book, Joint work, English, Atsuo Yoshino, Yasumasa Okamoto, Shigeto Yamawaki

Invited Lecture, Oral Presentation, Poster Presentation

  1. Changes in resting-state functional connectivity after cognitive behavioral therapy for chronic pain, Yoshino A, Okamoto Y, Okada G, Yokoyama S, Jinnin R, Takamura M, Ichikawa N and Yamawaki S, Neuroscience 2018, 2018/11/05, Without Invitation, English
  2. Similarities and differences of spontaneous neural activity in patients with chronic pain and depression: A resting state fMRI study, Atsuo Yoshino, Yasumasa Okamoto, Naofumi Otsuru, Go Okada, Shigeto Yamawaki, 16th World Congress on Pain, 2016, Without Invitation, English
  3. Distinctive spontaneous neural activity in patients with somatoform pain disorder: A resting state fMRI study, Yoshino Atuo, Yamawaki Shigeto, The International College of Neuropsychopharmacology, 2014/06/22, Without Invitation, English
  4. Neural responses to low-pain stimuli during sadness in patients with somatoform pain disorder: An fMRI study, World Congress of Biological Psychiatry, 2013, Without Invitation
  5. Sadness enhances the experience of pain and affects brain regions associated with pain, The International College of Neuropsychopharmacology, 2012, Without Invitation
  6. Emotional regulation of cortical activations evoked by pain perception – an MEG study–, Society for Neuroscience, 2008, Without Invitation
  7. Usefulness of spatial filter on the pain perception: an MEG study., International Society for the Advancement of Clinical Magnetoencephalography, 2006, Without Invitation

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2018, 2021
  2. KAKENHI, 2015, 2017
  3. KAKENHI, 2015, 2018
  4. KAKENHI, 2012, 2014

Social Activities

History as Peer Reviews of Academic Papers

  1. 2020, Journal of Pain Research
  2. 2020, Journal of Affective Disorders
  3. 2020, Frontiers in Human Neuroscience
  4. 2019, Frontiers in Psychology
  5. 2019, Frontiers in Neuroscience
  6. 2019, Brain and Behavior
  7. 2019, Biopsychosocial Medicine
  8. 2018, Scientific Reports
  9. 2018, Brain Imaging and Behavior
  10. 2017, Neuropsychiatry
  11. 2017, Journal of Neuroimaging
  12. 2016, Scientific Reports
  13. 2016, PlosOne
  14. 2016, Journal of International Medical Research
  15. 2016, Brain and Behavior, Others
  16. 2015, Psychology & Psychotherapy, 1
  17. 2015, Psychiatry and Clinical Neuroscience, 1
  18. 2015, The Tohoku Journal of Experimental Medicine, 1
  19. 2014, Clinical Neurophysiology, 1