KUNIKO MIZUTA

Last Updated :2026/07/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Assistant Professor
E-mail
mihtahiroshima-u.ac.jp
Self-introduction
I am an oral surgeon and specialize in the treatment of jaw deformities and maxillofacial trauma. I'm also interested in the research of cemento-osseous lesions of the jaws.

Basic Information

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Affiliated Academic Societies

  • The Japanese Society of Oral and Maxillofacial Surgeons
  • The Japanese Society for Jaw Deformities
  • Japanese Society of Oral Oncology
  • Japanese Association for Oral Infectious Diseases

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, 4Term, Overview of Dentistry
  2. 2026, Undergraduate Education, 3Term, Examination and Diagnosis
  3. 2026, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
  4. 2026, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
  5. 2026, Undergraduate Education, First Semester, Dental Research Practices I
  6. 2026, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine III
  7. 2026, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine IV
  8. 2026, Undergraduate Education, Second Semester, Dental Research Practices II
  9. 2026, Undergraduate Education, 2Term, Advanced Course in Applied Oral Biology and Medicine
  10. 2026, Undergraduate Education, 2Term, Advanced Course in Oral and Maxillofacial Medicine
  11. 2026, Undergraduate Education, First Semester, Dental Research Practices III
  12. 2026, Undergraduate Education, Year, Clinical Practice (Oral Surgery II)
  13. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Oral and Maxillofacial Surgery
  14. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Oral and Maxillofacial Surgery
  15. 2026, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Oral and Maxillofacial Surgery
  16. 2026, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Oral and Maxillofacial Surgery

Research Activities

Academic Papers

  1. Malignant ossifying fibromyxoid tumor of the tongue: case report and review of the literature, HEAD & FACE MEDICINE, 9, 20130624
    Link to Paper Search Results by DOI
  2. TMEM16E (GDD1) exhibits protein instability and distinct characteristics in chloride channel/pore forming ability., J Cell Physiol, 20130701
  3. Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: Predominant localization in pancreatic polypeptide-secreting PP-cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 351(2), 474-480, 20061215
    Link to Paper Search Results by DOI
  4. Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies, AMERICAN JOURNAL OF HUMAN GENETICS, 86(2), 213-221, 20100212
    Link to Paper Search Results by DOI
  5. Toll-like receptor (TLR) expression and TLR‑mediated interleukin-8 production by human submandibular gland epithelial cells., Molecular medicine reports, 10(5), 2377-2382, 2014
    Link to Paper Search Results by DOI
  6. TMEM16E (GDD1) exhibits protein instability and distinct characteristics in chloride channel/pore forming ability., Journal of cellular physiology, 229(2), 181-190, 2014
    Link to Paper Search Results by DOI
  7. Transgenic expression of a mutated cyclin-dependent kinase 4 (CDK4/R24C) in pancreatic beta-cells prevents progression of diabetes in db/db mice., Diabetes research and clinical practice., 82(1), 33-41, 2008
  8. A case of synchronous double cancer of the posterior mandible : cystadenocarcinoma and papillary thyroid carcinoma, Journal of Oral Surgery Society of Japan, 58(5), 322-326, 20120520
  9. Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients., Experimental and therapeutic medicine, 12(3), 2016
  10. Correlation of CENP-F gene expression with tumor-proliferating activity in human salivary gland tumors., Oral oncology, 41(7), 2005
  11. Increased expression of CENP-H gene in human oral squamous cell carcinomas harboring high-proliferative activity., Oncology reports, 16(5), 2006
  12. Histopathological evaluation including cytokeratin 13 and Ki-67 in the border between Lugol-stained and -unstained areas., Oncology reports, 24(1), 9-14, 20100701
  13. Molecular characterization of GDD1/TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia., Biochemical and biophysical research communications, 357(1), 126-132, 20070501

Invited Lecture, Oral Presentation, Poster Presentation

  1. Usefulness of Ketamine in Total Intravenous Anesthesia During Maxillomandibular Osteotomy, Mitsuhiro Yoshida, Shigehiro Ono, Eiji Imado, Hisanobu Kamio, Kuniko Mizuta, Serika Imamura, Aya Oda, Kana Oue, Mitsuru Doi, Yoshitaka Shimizu, Hiroshi Hanamoto, 2026 IADR/AADOCR/CADR General Session & Exhibition, 2026/03/27, Without Invitation, English
  2. A Case of Basal Cell Nevus Syndrome Undergoing Simultaneous Orthognathic Surgery and Maxillary Cystectomy., Mihiro KITAMURA, Kuniko MIZUTA, Miyuki SAKUMA, Yuko SHINTAKU, Yutaka MATSUSHITA, Masataka HIGUCHI, Tomonao AIKAWA, The 64th congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, 2025/11/06, Without Invitation, English
  3. Pattern of Pterygomaxillary Disjunction in Le Fort I Osteotomy by Leverage Technique., Yuzo TAKEDA, Kuniko MIZUTA, Shigehiro ONO, Ryo UETSUKI, Rena SHIDO, Takayuki NAKAGAWA, Yuka MIYAHARA, Yasuki ISHIOKA, Miyuki SAKUMA, Mihiro KITAMURA, and Tomonao AIKAWA, The 64th congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, 2025/11/06, Without Invitation, English
  4. A Case of Basal Cell Nevus Syndrome Undergoing Simultaneous Orthognathic Surgery and Maxillary Cystectomy., Mihiro KITAMURA, Kuniko MIZUTA, Miyuki SAKUMA, Yuko SHINTAKU, Yutaka MATSUSHITA, Masataka HIGUCHI, Tomonao AIKAWA, The 64th congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, 2025/11/06, Without Invitation, English
  5. Stability of Multi-segmental Le Fort I Osteotomy using CAD/CAM Splints, Yuka MIYAHARA, Yuzo TAKEDA, Rena SHIDO, Ryo UETSUKI, Yasuki ISHIOKA, Takayuki NAKAGAWA, Shigehiro ONO, Sayuri INOUE, Ayako INOUE, Yasuko INOUE, Yuko SHINTAKU, Masataka HIGUCHI, Yutaka MATSUSHITA, Miyuki SAKUMA, Kuniko MIZUTA, Tomonao AIKAWA, The 64th congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, 2025/11/06, Without Invitation, English
  6. A retrospective study of unfavorable splits/fractures in orthognathic surgery., Miyuki SAKUMA, Kuniko MIZUTA, Ryo UETSUKI, Takayuki NAKAGAWA, Rena SHIDO, Masataka HIGUCHI, Yutaka MATSUSHITA, Shigehiro ONO, and Tomonao AIKAWA., The 5th Joint German-Japanese CMF (Goethe Symposium), 2025/06/07, Without Invitation, English
  7. Remodeling of glenoid fossa of temporal bone after costochondral grafting for bilateral condylar process defects., Ryo Uetsuki, Kuniko Mizuta, Shigehiro Ono, Hiroshi Murozumi, Yasuki Ishioka, Yuko Shintaku, Yutaka Matsushita, Masataka Higuchi, and Tomonao Aikawa., The 5th Joint German-Japanese CMF symposium (Goethe Symposium), 2025/11/06, Without Invitation, English
  8. A Retrospective Study of unfavorable splits/fractures in Bilateral Sagittal Split Ramus Osteotomy, Miyuki SAKUMA, Kuniko MIZUTA, Ryo UETSUKI, Takayuki NAKAGAWA, Rena SHIDO, Masataka HIGUCHI, Yutaka MATSUSHITA, Shigehiro ONO, Tomonao AIKAWA., 2025/05/10, Without Invitation, English
  9. A Comprehensive Checklist for skeletal Class II dentofacial deformity with temporomandibular disorder, Kuniko MIZUTA, Miyuki SAKUMA, Tomonao AIKAWA, 2026 TAOMS, 2026/03/15, With Invitation, English
  10. Management of preventing unfavorable split / fracture in orthognathic surgery., Sakuma M, Mizuta K, Ono S, Aikawa T, 2024/10/05, Without Invitation, English
  11. Orthognathic surgery for retrognathia patients with mandibular condylar resorption, Mizuta K, Aikawa T, 74th congress of the German association for Oral and Maxillofacial Surgery, JAPANESE-GERMAN SESSION – ORTHOGNATHIC SURGERY., 2024/06/07, Without Invitation, English
  12. A case of bone resorption in mentum caused by hyaluronic acid filler in patient with skeletal Class II jaw deformity., Nakagawa T, Ono S, Sakuma M, Ishida Y, Mizuta K, Uetsuki R, Ohdan K, Shintaku U, Higuchi M, Matsushita Y, Kojima S, Hirata I, Kato K, Aikawa T, 2023/10/26, Without Invitation, English
  13. Total temporomandibular joint replacement in ICR / PCR: two case reports., Ono S, Uetsuki R, Nakagawa T, Sakuma M, Mizuta K, Ishida Y, Ishioka Y, Aikawa T, The 62nd Congress of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons, 2023/10/26, Without Invitation, English
  14. A case of costochondral graft reconstruction applied to a patient with micrognathia with open bite due to bilateral mandibular condyle defects., Mizuta K, Uetsuki R, Ono S, Shintaku U, Matsushita Y, Higuchi M, Nakagawa T, Morita C, Kurosaka H, Yamashiro T, Aikawa T, 2023/10/26, Without Invitation, English
  15. Chemical inhibition of LSD1 leads to epithelial to mesenchymal transition in vitro of an oral squamous cell carcinoma OM-1 cell line via release from LSD-1 dependent suppression of ZEB1, Yamakado N, Tobiume K, Uetsuki R, Ono S, Mizuta K, Nakagawa T, Aikawa T, 2023/06/03, Without Invitation, English
  16. A Case of Horizontal Alveolar Bone Resorption treated by Splitcrest Technique and GBR with Interconnected Porous Hydroxyapatite Ceramics, Sasaki K, Ninomiya Y, Tsuka H, Ishida F, Mizuta K, Ono S, Ohta K, Tsuga K, Takechi M, 2019/06/15, Without Invitation, English
  17. A case of skeletal maxillary protrusion with open bite and hypoplasia of the condyle treated using maxillary surgery alone, 2019/06/15, Without Invitation, English
  18. Docetaxel markedly reduced lung metastases of epithelioid angiosarcoma arising in the mandible: A case report, MIZUTA Kuniko, OHTA Kouji, FUJIMOTO Shinichi, TAKECHI Masaaki, 2016/11/26, Without Invitation, Japanese
  19. Clinico-statistical study of prognostic prediction using pre-treatment PET/CT in oral cancer patients, 2014/10/17, Without Invitation, Japanese
  20. Study of prognostic prediction using pre-treatment PET/CT in oral cancer patients, Kuniko Mizuta, Kouji Ohta, Shinichi Fujimoto, Ryo Uetsuki, Masaaki Takechi, 96th AAOMS Annual Meeting, 2014/09/11, Without Invitation, English
  21. Characterization of TMEM16E/GDD1 That Causes Gnatho-Diaphyseal Dysplaseia and Limb-Girdle Muscular Dystrophy through Distinct Gene Mutations, Kazumi Kubozono, Kuniko Mizuta, Shinichi Fujimoto, Masaaki Takechi, 96th AAOMS Annual Meeting, 2014/09/11, Without Invitation, English
  22. Prognostic utility of standardized uptake value using pre-treatment PET/CT in oral cancer patients., Kuniko Mizuta, Kouji Ohta, Shigehiro Ono, Takayuki Nakagawa, Shinichi Fujimoto, Toshiya Okumura, Ryo Uetsuki, Masaaki Takechi, 2014/06/21, Without Invitation, English
  23. Functional analysis of gene TMEM16E/GDD1 that causes Gnatho-Diaphyseal Dysplaseia and Limb-Girdle Muscular Dystrophy, Kazumi Kubozono, Kuniko Mizuta, Shinichi Fujimoto, Masaaki Takechi, 2014/06/21, Without Invitation, English
  24. Osteosynthesis of bilateral sagittal split ramus osteotomy for jaw deformities with degenerative temporomandibular joint disease using flexible titanium plates., Sakuma M,Mizuta K, Shintaku U, Higuchi M, Matsushita Y, Shido R, Uetsuki R, Nakagawa T, Ono S, , Aikawa T, 2024/11/08, Without Invitation, English
  25. A study of modified Inverted L-Shaped Ramus Osteotomy for patients with condylar resorption., Shido R,Nakagawa T, Ono S, Mizuta K, Uetsuki R, Shintaku U, Ishioka Y, Ishia Y, Sakuma M, Higuchi M, Matsushita Y, ,Aikawa T, 2024/11/08, Without Invitation, English
  26. A Retrospective Study of unfavorable split / fracture in Bilateral Sagittal Split Ramus Osteotomy, Mizuta K, Sakuma M, Uetsuki R, Nakagawa T, Shido R, Ono S, , Aikawa T, 2024/11/08, Without Invitation, English