TAKEHIRO HIRAO

Last Updated :2025/10/07

Affiliations, Positions
Graduate School of Advanced Science and Engineering, Associate Professor
Web Site
E-mail
thiraohiroshima-u.ac.jp
Other Contact Details
1–3–1 Kagamiyama, Higashi-Hiroshima, Hiroshima, Japan, Japan
TEL : (+81)82-424-7138 FAX : (+81)
Self-introduction
My research currently focuses on the development of non-covalently linked supramolecular polymeric ensembles.

Basic Information

Major Professional Backgrounds

  • 2013/04, Japan Society for the Promotion of Science, JSPS research fellow (DC1)
  • 2016/04, University of Texas at Austin, postdoctoral fellow
  • 2018/04, 2020/03/31, Hiroshima University, Graduate School of Science, Assistant Professor
  • 2020/04/01, 2024/03/31, Hiroshima University, Graduate School of Advanced Science and Engineering, Assistant Professor
  • 2024/04/01, Hiroshima University, Graduate School of Advanced Science and Engineering, Associate Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Science , Chemistry Ph.D., Japan, 2013/04, 2016/03
  • Hiroshima University, Graduate School of Science , Japan, 2011/04, 2013/03

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Research Fields

  • Chemistry;Basic chemistry;Organic chemistry

Research Keywords

  • Supramolecular chemistry
  • Noncovalent polymer
  • Organic Chemistry

Affiliated Academic Societies

  • The chemical society of Japan
  • The society of polymer science, Japan
  • The society of synthetic organic chemistry, Japan

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  2. 2025, Undergraduate Education, First Semester, Special Study for Graduation
  3. 2025, Undergraduate Education, Second Semester, Special Study for Graduation
  4. 2025, Undergraduate Education, Second Semester, Exercises in Organic Chemistry
  5. 2025, Undergraduate Education, First Semester, Chemical Experiments I
  6. 2025, Undergraduate Education, Second Semester, Chemical Experiments II
  7. 2025, Undergraduate Education, 2Term, Basic Chemistry B
  8. 2025, Graduate Education (Master's Program) , 1Term, Introduction to Organic Chemistry
  9. 2025, Graduate Education (Master's Program) , First Semester, Exercises in Chemistry A
  10. 2025, Graduate Education (Master's Program) , Second Semester, Exercises in Chemistry B
  11. 2025, Graduate Education (Master's Program) , Year, Master's Thesis in Chemistry
  12. 2025, Graduate Education (Doctoral Program) , Year, Doctoral Thesis in Chemistry

Research Activities

Academic Papers

  1. Vortex-Flow-Directed Chiral Macroscopic Ordering of Platelet Nanostructures Formed via the Supramolecular Assembly of Platinum Complexes with Bis(phenylisoxazolyl)benzene, J. Am. Chem. Soc., 147, 30674-30683, 2025
  2. Mechano-responsive color changes of a Pt(II) complex possessing triethylene glycol towards pressure sensors, RSC Adv., 15, 21401-21407, 2025
  3. Single-crystal-to-single-crystal transformation based on ionophore-like transport, Chem. Lett., upae252, 2025
  4. Chiral Induction of a Tetrakis(porphyrin) in Various Chiral Solvents, Chem. –Eur. J., 30, e202403569, 2024
  5. Controlled Helical Organization in Supramolecular Polymers of Pseudo-Macrocyclic Tetrakisporphyrins, Angew. Chem. Int. Ed., 63, e202416770, 2024
  6. ★, Latent porosity of planar tris(phenylisoxazolyl)benzene, Nature Commun., 15, 8314, 2024
  7. Synthesis of Supramolecular Polymers, Handbook of Functional Polymers, Chapter 40: Supramolecule, Y. Chujo Ed., 2024
  8. Spectrally Selectuve Leakage of Light from Self-Assembled Supramolecular Nanofiber Waveguides Induced by Surface Plasmon Polaritons, J. Phys. Chem. C, 128, 4295-4302, 2024
  9. Supramolecular polymerization behavior of a ditopic self-folding biscavitand, Bull. Chem. Soc. Jpn., 97, uoad016, 2024
  10. Nanoarchitectonics of supramolecular porphyrins based on a bis(porphyrin) cleft molecule, JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 27(07N10), 966-979, 202310
  11. Supramolecular chiral sensing by supramolecular helical polymers, CHEMICAL COMMUNICATIONS, 59(17), 2421-2424, 20230223
  12. Macromolecular architectures constructed by biscalix[5]arene-[60]fullerene host-guest interactions, POLYMER JOURNAL, 55(2), 95-104, 202302
  13. Development of Supramolecular Polymers with Unique Chain Structures, Supramolecular Nanotechnology: Advanced Design of Self-Assembled Functional Materials, ISBN-10: 3527349480, 2023
  14. Lanthanide and Actinide Ion Complexes Containing Organic Ligands Investigated by Surface-Enhanced Infrared Absorption Spectroscopy, Inorg. Chem., 62, 474-496, 2023
  15. Improved synthesis of tetrakis(porphyrin) molecular cleft via palladium-mediated cross-coupling between a bis(porphyrin) boronic ester and bis(iodophenyl)butadiyne, J. Porphyr. Phthalocyanines, 2022
  16. Nonporous Adaptive Crystals for Separations, Kagaku, 77(8), 64-65, 2022
  17. Self-assembly of neutral platinum complexes controlled by thermal inputs, Chem. Commun., 58, 8356-8359, 2022
  18. Supramolecular Ensembles Formed via Calix[5]arene-Fullerene Host-Guest Interactions, Chem. Asian J., 17, e202200344, 2022
  19. Chiral Supramolecular Polymer Formed via Host-Guest Complexation of an Octaphosphonate Biscavitand and a Chiral Diammonium Guest, Bull. Chem. Soc. Jpn., 95, 621-627, 2022
  20. Non-Racemically Twisted Supramolecular Fullerene Polymers, KOBUNSHI, 71(1), 6-6, 2022
  21. ★, Self-Sorting Behavior in Supramolecular Fullerene Polymerization Directed by Host-Guest Complexation between Calix[5]arene and C60, Chem. Commun., 57, 11831-11834, 2021
  22. Solvent-Directed Formation of Helically Twisted Stacking Constructs via Self-Assembly of Tris(phenylisoxazolyl)benzene Dimers, Org. Biomol. Chem., 19, 7165-7171, 2021
  23. Gas-Phase UV Spectroscopy of Chemical Intermediates Produced in Solution: Oxidation Reactions of Phenylhydrazines by DDQ, J. Phys. Chem. A, 125, 6697-6702, 2021
  24. Self-Complementary Structure of Bisporphyrin Dimer, Chem. Lett., 50, 1844-1847, 2021
  25. Negative Cooperativity in Guest Binding of a Ditopic Self-Folding Biscavitand, Org. Lett., 23, 6217-6221, 2021
  26. SUPRAMOLECULAR CHEMISTRY OF FULLERENES, Handbook of Fullerene Science and Technology, in Press, 2021
  27. ★, Polymerization of a biscalix[5]arene derivative, RSC Adv., 11, 17587-17594, 2021
  28. Self-assembly of neutral platinum complexes possessing chiral hydrophilic TEG chains, Org. Bio. Chem., 19, 5303-5311, 2021
  29. Self-Assembling Behavior and Chiroptical Properties of Carbazole-Cored Phenyl Isoxazolyl Benzenes, J. Org. Chem., 86(8), 5499-5505, 2021
  30. ★, Helically Organized Fullerene Array in a Supramolecular Polymer Main Chain, J. Am. Chem. Soc., 143, 4339-4345, 2021
  31. Stereoselectivity in Dehydrative Cyclic Trimerization of Substituted 4-Alkylaminobenzoic Acids, New J. Chem., 45, 1187-1193, 2021
  32. A Light Harvesting/Charge Separation Model with Energy Gradient Made of Assemblies of meta-pyridyl Zinc Porphyrins, Chem. Eur. J., 27, 4053-4063, 2021
  33. Supramolecular fluorescent sensors: An historical overview and update, Coord. Chem. Rev., 15(427), Article number 213560, 2021
  34. Self-Healing Supramolecular Materials Constructed by Copolymerization via Molecular Recognition of Cavitand-based Coordination Capsules, Angew. Chem. Int. Ed., 59, 16690-16697, 2020
  35. A dual redox-responsive supramolecular polymer driven by molecular recognition between bisporphyrin and trinitrofluorenone, Chemical Communications, 56, 7553-7556, 2020
  36. Helicity of a polyacetylene directed by molecular recognition of biscalixarene and fullerene, Chemical Communications, 56, 6672-6675, 2020
  37. Columnar Organization of Carbo[5]helicene Directed by Peripheral Steric Perturbation, Organic Letter, 22, 5294-5298, 2020
  38. ★, Supramolecular Approach to Polymer-Shape Transformation via Calixarene–Fullerene Complexation, Macromolecules, 53(9), 3563-3570, 2020
  39. Supramolecular Polymerization and Functions of Isoxazole Ring Monomers, Chem. Lett., 49, 574-584, 2020
  40. AIE-active micelles formed by self-assembly of an amphiphilic platinum complex possessing isoxazole moieties, Chem. Commun., 56, 1137-1140, 2020
  41. Helical assembly of a dithienogermole exhibiting switchable circularly polarized luminescence, Chemical Communications, 55, 10607-10610, 2019
  42. Ring–Chain Competition in Supramolecular Polymerization Directed by Molecular Recognition of the Bisporphyrin Cleft, Macromolecules, 52(16), 6160-6168, 2019
  43. Supramolecular Properties of a Monocarboxylic Acid-Functionalized Texas-Sized Molecular Box, J. Am. Chem. Soc., 6823-6831, 2018
  44. ★, Control over multiple molecular states with directional changes driven by molecular recognition, Nat. Commun., 823, 2018
  45. ★, Sequence-controlled supramolecular terpolymerization directed by specific molecular recognitions, Nat. Commun., 634, 2017
  46. Slow Intermolecular Complexation–Decomplexation Exchanges of Cyclodextrins in Fullerene and Its Derivative Complexes, ChemistrySelect, 11322-11327, 2017
  47. Synthesis of Optically Active Conjugated Polymers Containing Platinum in the Main Chain: Control of the Higher-Order Structures by Substituents and Solvents, J. Polym. Sci., Part A: Polym. Chem., 2452-2461, 2015
  48. Synthesis and Properties of Novel Optically Active Platinum-containing Poly(phenyleneethynylene)s, Chem. Lett., 937-939, 2016
  49. Supramoelcular Porphyrin Copolymer Assembled through Host-Guest Interactions and Metal-Ligand Coordination, Angew. Chem. Int. Ed., 14830-14834, 2015
  50. Liposome collapse resulting from an allosteric interaction between 2,6-dimethyl-b-cyclodextrins and lipids, RSC Adv., 77746-77754, 2015
  51. ★, Supramolecular Fullerene Polymers and Networks Directed by Molecular Recognition between Calix[5]arene and C60, Chem. –Eur. J., 16136-16146, 2014
  52. Self-Assembly of Oligo(phenylisoxazolyl)benzenes Induced by Multiple Dipole-Dipole Interactions, Chem. Lett., 414-416, 2013
  53. Synthesis of Optically Active Poly(m-phenyleneethynylene-aryleneethynylene)s Bearing Hydroxy Groups and Examination of the Higher Order Structures, Macromolecules, 8161-8170, 2013
  54. Circular Dichroism and Circularly Polarized Luminescence Triggered by Self-Assembly of Tris(phenylisoxazolyl)benzene Possessing Perylenebisimide, Chem. Commun., 6025-6027, 2012
  55. Supramolecular Polymerization Triggered by Molecular Recognitioin between Bisporphyrin and Trinitrofluorenone, Angew. Chem. Int. Ed., 1473-1476, 2012

Invited Lecture, Oral Presentation, Poster Presentation

  1. N/A, Yuma Nakamura, Shin-ichi Kihara, Takehiro Hirao. Takeharu Haino, 2025/09/16, Without Invitation, Japanese
  2. N/A, 2025/09/05, Without Invitation, Japanese
  3. N/A, Mao kawasaki, Masaya Yoshida, Yudai Ono, Takehiro Hirao, Takeharu Haino, 2025/08/28, Without Invitation, Japanese
  4. N/A, Ayako Ema, Chikara Azuma, Yuma Nakamura, Takehiro Hirao, Takeharu Haino, 2025/08/28, Without Invitation, Japanese
  5. N/A, Masato Yomori, Takehiro Hirao, Takeharu Haino, 2025/08/28, Without Invitation, Japanese
  6. Selective Solvent Adsorption and Separation Using Latent Porosity in Crystalline Compound of Tris(phenylisoxazolyl)benzene Derivative, Yudai Ono, Takehiro Hirao, Naomi Kawata, Takeharu Haino, The 19th Pacific Polymer Conference (PCC19), 2025/07/09, Without Invitation, English
  7. Mechano-responsive emission color change of platinum complexes possessing pheny|(isoxazolyl) group, Takehiro Hirao, Masaya Yoshida, Shin-ichi Kihara, Takeharu Haino, The 19th Pacific Polymer Conference (PCC19), 2025/07/09, Without Invitation, English
  8. N/A, Ayako Ema, Koki Hamada, Chikara Azuma, Yuma Nakamura, Takehiro Hirao, Takeharu Haino, 2025/06/08, Without Invitation, Japanese
  9. N/A, Yuma Nakamura, Shin-ichi Kihara, Takehiro Hirao, Takeharu Haino, 2025/06/07, Without Invitation, Japanese
  10. Selective Molecular Adsorption and Separation Using Latent Porosity in Crystalline Compound of Tris (phenylisoxazolyl) benzene, Yudai Ono, Takehiro Hirao, Naomi Kawata, Takeharu Haino, The 19th International Symposium on Macrocyclic and Supramolecular Chemistry in conjunction with 9th NanoLSI Symposium (ISMSC 2025), 2025/05/29, Without Invitation, English
  11. N/A, Yuma Nakamura, Shin-ichi Kihara, Takehiro Hirao, Takeharu Haino, 2025/03/28, Without Invitation, Japanese
  12. N/A, Sumireko Sasaki, Naoka Fujii, Takehiro Hirao, Takeharu Haino, 2025/03/27, Without Invitation, Japanese
  13. N/A, Yudai Ono, Takehiro Hirao, Naomi Kawata, Takeharu Haino, 2025/03/27, Without Invitation, Japanese
  14. Mechano-responsive behaviors of platinum complexes possessing phenyl(isoxazolyl) groups, Takehiro Hirao, Masaya Yoshida, Takeharu Haino, CSJ Annual Meeting, 2025/03/27, Without Invitation, English, Osaka
  15. N/A, Ayako Ema, Takehiro Hirao, Takeharu Haino, 2025/03/26, Without Invitation, Japanese
  16. Development of Photo-Degradable Supramolecular Graft Polymer Gels Formed by Molecular Recognition of Cavitand-Based Self-Assembled Capsule and Guest-Attached Polyester, Yuma Nakamura, Natsumi Nitta, Shin-ichi Kihara, Takehiro Hirao, and Takeharu Haino, The 21st Nano Bio Info Chemistry Symposium, 2024/12/05, Without Invitation, English
  17. N/A, Yuma Nakamura, Takehiro Hirao, Takeharu Haino, 2024/11/12, Without Invitation, Japanese
  18. N/A, Ryota Kameda, Takehiro Hirao, Takeharu Haino, 2024/11/12, Without Invitation, Japanese
  19. N/A, Naoyuki Hisano, Soichiro Koya, Naoka Fujii, Takehiro Hirao, Takeharu Haino, 2024/09/25, With Invitation, Japanese
  20. N/A, Yudai Ono, Takehiro Hirao, Naomi Kawata, Takeharu Haino, 2024/09/25, With Invitation, Japanese
  21. N/A, 2024/09/11, Without Invitation, Japanese
  22. Chiroptical response in supramolecular assemblies of isoxazole-equipped platinum(II) complex, Masaya Yoshida, Takehiro Hirao, Kyota Yasuda, Takuma Matsumoto, Shin-ichi Tate, Martin Vacha, Takeharu Haino, Chirality 2024, 2024/08/26, Without Invitation, Japanese
  23. Latent Porosity of a Tris(methoxyphenylisoxazolyl)benzene, Takehiro Hirao, Yudai Ono, Naomi Kawata, and Takeharu Haino, 2024/06/07, Without Invitation, English
  24. N/A, Yudai Ono, Nozomu Suzuki, Takehiro Hirao, Takeharu Haino, 2024/06/01, Without Invitation, Japanese
  25. N/A, Yuki Seno, Yudai Ono, Takehiro Hirao, Takeharu Haino, 2024/06/01, Without Invitation, Japanese
  26. Guest encapsulation behaviors of a tris(phenylisoxazolyl)benzene derivative, 2024/06/01, Without Invitation, Japanese, Kyoto
  27. Vortex flow induced chiroptical response of self-assembled supramolecular objects of isoxazole-equipped platinum(II) complex, Masaya Yoshida, Takehiro Hirao, Takeharu Haino, 2024/03/21, Without Invitation, English
  28. Latent Porosity and Selective Molecular Adsorption in a Molecular Crystal of Tris(phenylisoxazolyl)benzene, Yudai Ono, Takehiro Hirao, Takeharu Haino, 2024/03/18, Without Invitation, Japanese
  29. Selective Solvent Adsorption in Molecular Crystal of Tris(phenylisoxazolyl)benzene, Yudai Ono, Takehiro Hirao, and Takeharu Haino, The 20th Nano Bio Info Chemistry Symposium, 2023/12/08, Without Invitation, English
  30. Synthesis and chiroptical properties of supramolecular porphyrin polymers, Takehiro Hirao, Sei Kishino, Takeharu Haino, 72nd Symposium on Macromolecules, 2023/09/27, With Invitation, Japanese, kagawa
  31. N/A, 2023/09/26, Without Invitation, Japanese
  32. N/A, 2023/09/26, Without Invitation, Japanese
  33. N/A, 2023/09/26, Without Invitation, Japanese
  34. N/A, 2023/09/21, Without Invitation, English
  35. Self-Assembly of Hydrogen-BondedTris(phenylisoxazolyl)benzene Dimers, Yudai Ono, Takehiro Hirao, Takeharu Haino, 19th International Conference on Chiroptical Spectroscopy, 2023/09/17, Without Invitation, Japanese
  36. N/A, 2023/09/05, Without Invitation, Japanese
  37. Development of supramolecular fullerene assemblies via host-guest interactions, Takehiro Hirao, 2023/09/05, With Invitation, Japanese
  38. N/A, 2023/06/21, Without Invitation, Japanese
  39. Pathway complexity in the self-assembly process of platinum complexes possessing TEG chains, Takehiro Hirao, Masaya Yoshida, Takeharu Haino, The 103rd CSJ Annual Meeting, 2023/03/24, Without Invitation, English, Chiba
  40. N/A, 2023/03/22, Without Invitation, Japanese
  41. N/A, 2023/03/18, Without Invitation, Japanese
  42. Takehiro, Hirao, School of Chemistry and Chemical Engineering, Huazhong University of Science & Technology (HUST), Invited Lecture, 2022/12/22, With Invitation, English
  43. Supramolecular helical polymers generated by metal coordination of biscavitand, Koiki Hamada, Daisuke Shimoyama, Takehiro Hirao, and Takeharu Haino, The 19th Nano Bio Info Chemistry Symposium, 2022/12/16, Without Invitation, Japanese
  44. Takehiro, Hirao, Naoka Fujii, Yoshiki Iwabe, Takeharu Haino, 2022/12/16, Without Invitation, Japanese
  45. Self-assembly of platinum(II) complexes possessing chiral triethylene glycol chains, Masaya Yoshida, Takehiro Hirao, and Tekeharu Haino, 8th Asian Conference on Coordination Chemistry (ACCC8), 2022/08/07, Without Invitation, English
  46. Self-Assembling Behavior of Hydrogen-Bonded Tris(phenylisoxazolyl)benzene Dimer, Yudai Ono, Takehiro Hirao, and Takeharu Haino, 25th IUPAC International Conference on Physical Organic Chemistry (ICPOC-25), 2022/07/10, Without Invitation, Japanese
  47. Takehiro, Hirao, 2022 International Conference on Modern Challenges in Polymer Science and Technology (2022 MCPST), 2022/01/18, With Invitation, English, Taiwan (online)
  48. Takehiro, Hirao, 2021/11/04, With Invitation, Japanese
  49. Synthesis and Cooperative Molecular Recognition of Homoditopic Host Molecule with Rebek's Cavitands, Haruna Fujimoto, Daisuke Shimoyama, Takehiro Hirao, and Takeharu Haino, 2021/03/19, Without Invitation, English
  50. Self-assembling behaviors of platinum (II) complexes possessing hydrophilic triethylene glycol chains, Masaya Yoshida, Takehiro Hirao, and Takeharu Haino, The 17th Nano Bio Info Chemistry Symposium, 2020/12/09, Without Invitation, English
  51. A Switchable Dual Redox-Responsive Supramolecular Polymer Possessing Bisporphyrin Cleft and Trinitrofluorenone, Naoyuki Hisano, Takehiro Hirao, and Takeharu Haino, 3rd GLowing Polymer Symposium in KANTO, 2020/11/28, Without Invitation, English
  52. Helically Organized Supramolecular Polymer Formed via Self-Assembly of Tetrakisporphyrin with Chiral Side Chain, Naoka Fujii, Tekehiro Hirao, and Takeharu Haino, 3rd GLowing Polymer Symposium in KANTO, 2020/11/28, Without Invitation, English
  53. Non-racemic helical polymers with fullerene array on the polymer backbone, Takehiro Hirao, Yoshiki Iwabe, Naoka Fujii, Takeharu Haino, 3rd GLowing Polymer Symposium in KANTO, 2020/11/28, Without Invitation, English
  54. Development of supramolecular network polymer through molecular recognition of bisporphyrin cleft, HISANO, Naoyuki; LAI, Nang Duy; HIRAO, Takehiro; HAINO,Takeharu, 2020/03/22, Without Invitation, English
  55. Ring–chain mechanism in supramolecular polymerization through molecular recognition of bisporphyrin cleft and trinitrofluorenone, Naoyuki Hisano, Takehiro Hirao, Shigehisa Akine, Shin-ichi Kihara, Takeharu Haino., The 16th Nano Bio Info Chemistry Symposium, 2019/12/07, Without Invitation, English
  56. Supramolecular Polymers Formed by Molecular Association of Bisporphyrin and Trinitrofluorene, Takehiro Hirao, 15th IUPAC International Conference on Novel Materials and their Synthesis (NMS-XV), 2019/09/06, With Invitation, English, Shenyang, China
  57. Mechanistic consideration on supramolecular polymerization of heteroditopic monomers possessing bisporphyrin cleft and trinitrofluorenone, Takehiro Hirao, Naoyuki Hisano, Shin-ichi Kihara, Shigehisa Akine, Takeharu Haino, 68th SPSJ Annual meeting, 2019/05/29, Without Invitation, English
  58. Self-Sorting-Directed Supramolecular Terpolymerization, Takehiro Hirao, Hiroaki Kudo, Tomoko Amimoto, Takeharu Haino, The 12th SPSJ International Polymer Conference (IPC2018), 2018/12/05, Without Invitation, English
  59. Synthesis of the noncovalently-linked sequence-regulated polymers formed by molecular recognition, Takehiro Hirao, Takeharu Haino, PACIFICHEM 2015, 2015/12/15, Without Invitation, English
  60. Development of supramolecular fullerene constructs via host-guest interaction between calix[5]arene and fullerene, Takehiro Hirao, 2023/11, With Invitation, Japanese

Awards

  1. 2022/05/31, the Matsuura Award, 広島化学同窓会

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI (Grant-in-Aid for Scientific Research (B))(daihyo), 2025, 2029
  2. KAKENHI (Grant-in-Aid for Scientific Research (A))(Buntan), 2025, 2029
  3. KAKENHI (Grant-in-Aid for Young Scientists), 2022, 2025
  4. KAKENHI (Grant-in-Aid for Scientific Research (A)) (collaborator), 2021, 2025
  5. 2021, 2024
  6. KAKENHI (Grant-in-Aid for Young Scientists), 2020, 2022
  7. KAKENHI (Grant-in-Aid for Research Activity Start-up), 2018, 2020
  8. KAKENHI (Grant-in-Aid for JSPS Fellows), 2013, 2016