NOBUTAKA HORIE

Last Updated :2024/02/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medical), Professor
E-mail
horiehiroshima-u.ac.jp
Self-introduction
I was appointed as a professor of neurosurgery at the Graduate School of Biomedical and Health Sciences(Medical), Hiroshima University on October 1, 2021.

Basic Information

Major Professional Backgrounds

  • 2021/10/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Professor
  • 2016/04/01, 2021/09/30, Nagasaki University, Neurosurgery, Lecturer/ Medical Office Manager
  • 2009/04/01, 2016/03/31, Nagasaki University, Neurosurgery, Assistant professor
  • 2008/04/01, 2009/03/31, Stanford University, Neurosurgery, postdoctoral fellow
  • 2006/04/01, 2008/03/31, Stanford University, Neurosurgery, Japan Society for the Promotion of Science Special Overseas Researcher
  • 2005/04/01, 2006/03/31, Ebisumachi Hospital, Neurosurgery, Doctor
  • 2002/06/01, 2005/03/31, Nagasaki University, Neurosurgery, Doctor
  • 2001/06/01, 2002/05/31, Fukuoka kinen hospital, Neurosurgery, doctor
  • 2000/06/01, 2001/05/31, Miyazaki hospital, Neurosurgery, doctor
  • 1999/06/01, 2000/05/31, Kitakyushu city yahata hospital, Neurosurgery, Resident
  • 1998/06/01, 1999/05/31, Nagasaki Rosai Hospital, Neurosurgery, Resident

Educational Backgrounds

  • Stanford University, Neurosurgery, USA, 2006/04/01, 2009/03/31
  • Nagasaki University, Graduate School of Biomedical Sciences, Medical science, Japan, 2002/04/01, 2006/03/31
  • Nagasaki University, School of medicine, Japan, 1992/04/01, 1998/03/31

Academic Degrees

  • Nagasaki University

Affiliated Academic Societies

  • The Japan Neurosurgical Society
  • The Japanese Society For Neuroendovascular Therapy
  • The Japan Stroke Society
  • The Japanese Congress of Neurological Surgeons
  • The Japanese Society of Cerebral Blood Flow and Metabolism
  • The Japan Society of Neurosurgical Emergency
  • Cardiovascular Stroke Society of Japan
  • Japanese Society for Neuroendoscopy
  • Neurosurgical Techniques and Tools
  • The Japan Academy of Neurosonology
  • American Stroke Association active member
  • European Stroke Organization active member

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, 4Term, Medical Neuroscience I
  2. 2023, Undergraduate Education, Year, Medical Neuroscience III
  3. 2023, Undergraduate Education, Intensive, Practice for medical research
  4. 2023, Undergraduate Education, Intensive, Practice of Medicine I
  5. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Neurosurgery
  6. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Neurosurgery
  7. 2023, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Neurosurgery
  8. 2023, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Neurosurgery

Research Activities

Academic Papers

  1. Epstein-barr Virus Negative Primary Central Nervous System Lymphoma Developed after Treatment of Glioblastoma: A Case Report, NMC Case Rep J, 15(9), 395-400, 202211
  2. Stem Cell Therapy for Acute/Subacute Ischemic Stroke with a Focus on Intraarterial Stem Cell Transplantation: From Basic Research to Clinical Trials, Bioengineering (Basel), 10(1):33(10(1):33), 10(1):33-10(1):33, 20221227
  3. Characteristics and therapeutic strategies of radiation-induced glioma: case series and comprehensive literature review, JOURNAL OF NEURO-ONCOLOGY, 159(3), 531-538, 202209
  4. Hypertension and Advanced Age Increase the Risk of Cognitive Impairment after Mild Traumatic Brain Injury: A Registry-Based Study, WORLD NEUROSURGERY, 162, E273-E280, 202206
  5. Diagnostic accuracy of MR vessel wall imaging at 2 weeks to predict morphological healing of vertebral artery dissection, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 31(10), 202210
  6. Assessment of intraoperative spinal angiography via the popliteal artery for spinal vascular diseases, World Neurosurgery, 20221014
  7. Recent Declining Trend of Incidence Rate of Subarachnoid Hemorrhage in Shimane, Japan: The Japan Incidence of Subarachnoid Hemorrhage (JIS) Study, Neurologia medico-chirurgica, 62(10), 458-464, 20221015
  8. Factors contributing to restenosis after carotid artery stenting and the usefulness of magnetic resonance plaque imaging: A study of 308 consecutive patients, European Journal of Radiology, 154, 20220901
  9. Diagnostic accuracy of MR vessel wall imaging at 2 weeks to predict morphological healing of vertebral artery dissection, Journal of Stroke and Cerebrovascular Diseases, 31(10), 20221001
  10. Hypertension and Advanced Age Increase the Risk of Cognitive Impairment after Mild Traumatic Brain Injury: A Registry-Based Study, World Neurosurgery, 162, 273-280, 20220101
  11. A nationwide registry study: The 5-factor modified frailty index of meningioma surgery in non-elderly and elderly patients, Clin Neurol Neurosurgery, 222, 20221101
  12. Natural history of acute unruptured vertebral basilar artery dissection: Temporal changes in imaging findings and contributory factors, Clin Neurol Neurosurgery, 20221101
  13. Changes in Short-Term Outcomes After Discharge in Patients with Aneurysmal Subarachnoid Hemorrhage: A Multicenter, Prospective, Observational Study, World Neurosurgery, 164, 1214-1225, 20220801
  14. Usefulness of stent placement for innominate artery stenosis via the right brachial artery under protection by balloon guide catheter: a technical case report, Acta Neurochir (Wien), 164(11), 2875-2880, 20221101
  15. Longitudinal electrophysiological changes after mesenchymal stem cell transplantation in a spinal cord injury rat model, PLoS One, 17(8), 20220805
  16. Abdominal Aortic Calcification Volume Is Associated with Wall Enhancement of Unruptured Intracranial Aneurysm, World Neurosurg, 167, 122-126, 20220807
  17. Characterization of cortical activity in juvenile myoclonic epilepsy by gradient magnetic field topography, Clin Neurophysiol., 141, 62-74, 20220901
  18. Natural course of Rathke's cleft cysts and risk factors for progression, Journal of Neurosurgery, 1-7, 20220902
  19. Characteristics and therapeutic strategies of radiation-induced glioma: case series and comprehensive literature review, J Neurooncol, 159(3), 531-538, 20220901
  20. Influence of growth hormone therapy on germinoma survivors, Pituitary, 20220820
  21. [Indications for Extracranial-Intracranial Bypass Surgery], No Shinkei Geka, 50(4), 727-734, 20220710
  22. Clinical Trial of the New Stent Retriever Tron FX for both Proximal and Distal Intracranial Large Vessel Occlusions, Journal of Stroke and Cerebrovascular Diseases, 30(3), 20210301
  23. Impact of Pre-operative Embolization With Onyx for Brain Arteriovenous Malformation Surgery, Frontiers in Neurology, 13, 20220426
  24. Ischemic Stroke as a Warning Sign of Impending Aneurysmal Rupture: A Report of Two Cases, NMC Case Report Journal, 8(1), 85-88, 20210402
  25. Clinical Trial of the New Stent Retriever Tron FX for both Proximal and Distal Intracranial Large Vessel Occlusions, Journal of Stroke and Cerebrovascular Diseases, 30(7), 20210701
  26. MAP Kinase Pathways in Brain Endothelial Cells and Crosstalk with Pericytes and Astrocytes Mediate Contrast-Induced Blood-Brain Barrier Disruption., Pharmaceutics., 13(8), 20210817
  27. Current status of a helicopter transportation system on remote islands for patients undergoing mechanical thrombectomy., PLoS One, 16(1), 20210119
  28. Hematoma expansion unrelated to rebleeding in ruptured anterior cerebral artery aneurysms treated by early endovascular embolization., Surgical Neurology International, 20211123
  29. Characteristics of aneurysmal subarachnoid hemorrhage associated with rheumatic disease, Neurosurgical Review, 44(5), 2611-2618, 20211001
  30. Ruptured aneurysm-induced pituitary apoplexy: illustrative case., Journal of Neurosurgery Case Lessons, 1, 20210628
  31. Characterization of cortical activity in juvenile myoclonic epilepsy by gradient magnetic field topography, CLINICAL NEUROPHYSIOLOGY, 141, 62-74, 202209
  32. Microsurgical Versus Endovascular Treatment of Spinal Epidural Arteriovenous Fistulas With Intradural Venous Drainage: A Multicenter Study of 81 Patients., J Neurosurg Spine, Apr 24(Apr 24), 1-11, 20200401
  33. Delayed Vasospasm Associated with Mechanical Thrombectomy for Acute Ischemic Stroke, World neurosurgery, 138, 197-199, 20200101
  34. Comparison of the rate of dedifferentiation with increasing passages among cell sources for an in vitro model of the blood-brain barrier, Journal of neural transmission (Vienna, Austria : 1996), 20200101
  35. Hyperhomocysteinemia Causes Severe Intraoperative Thrombotic Tendency in Superficial Temporal Artery-middle Cerebral Artery Bypass., Journal of stroke and cerebrovascular diseases. ahead of print, 20200101
  36. Traumatic Middle Meningeal Arteriovenous Fistula of Non-fractured Site Detected by Four-dimensional Computed Tomography Angiography: A Case Report., NMC case report journal, 7(2)(7(2)), 57-61, 20200101
  37. Surgical Venous Drainage Disconnection from Cavernous Sinus Dural Arteriovenous Fistula and Ruptured Varix, World neurosurgery, 137, 18-23, 20200101
  38. ★, Impact of perioperative aneurysm rebleeding after subarachnoid hemorrhage, J Neurosurg, Sep 13(Sep 13), 1-10, 20190901
  39. Impact of Mechanical Thrombectomy Device on Thrombus Histology in Acute Embolic Stroke, World Neurosurg, Dec;132(Dec;132), e418-e422, 20191201
  40. ★, Impact of basal ganglia damage after successful endovascular recanalization for acute ischemic stroke involving lenticulostriate arteries, J Neurosurg, May 31(May 31), 1-9, 20190501
  41. Arterial Spin Labeling Magnetic Resonance Imaging Can Identify the Occlusion Site and Collateral Perfusion in Patients with Acute Ischemic Stroke: Comparison with Digital Subtraction Angiography, Cerebrovasc Dis, 48, 70-76, 20190101
  42. Biomarkers of Cardiac Dysfunction as Risk Factors in Cryptogenic Stroke, Cerebrovasc Dis, 48(3-6)(48(3-6)), 132-139, 20190101
  43. Initial Experience of ORBEYE™ Surgical Microscope for Carotid Endarterectomy, Asian J Neurosurg, Jul-Sep;14(3)(Jul-Sep;14(3)), 839-842, 20190901
  44. Pericytes Suppress Brain Metastasis from Lung Cancer In Vitro, Cell Mol Neurobiol, Jan;40(1)(Jan;40(1)), 113-121, 20190101
  45. A score using left ventricular diastolic dysfunction to predict 90-day mortality in acute ischemic stroke, The DONE J Neurol Sci, Mar 15;398(Mar 15;398), 157-162, 20190301
  46. A Case of Dural Arteriovenous Fistula Involving the Superior Sagittal Sinus that Presented as a Primary Intraventricular Hemorrhage, No Shinkei Geka, Aug;47(8)(Aug;47(8)), 859-867, 20190801
  47. Middle Cerebral Artery Fenestration with M2 Fusion Detected during Aneurysm Clipping:A Case Report, No Shinkei Geka, Oct;47(10)(Oct;47(10)), 1089-1092, 20191001
  48. Assessment of veins in T2*-weighted MR angiography predicts infarct growth in hyperacute ischemic stroke., PLoS One., 20180401
  49. ★, Working Group for Guidelines on Development of Cell-Based Products for the Treatment of Cerebral Infarction. Accelerating Cell Therapy for Stroke in Japan: Regulatory Framework and Guidelines on Development of Cell-Based Products, Stroke, Apr;49(4)(Apr;49(4)), e145-e152, 20180401
  50. Early Diagnosis of Infective Endocarditis by Brain T2*-Weighted Magnetic Resonance Imaging, Circ J, Jan 25;82(2)(Jan 25;82(2)), 464-468, 20180101
  51. Revascularization for Aplastic or Twiglike Middle Cerebral Artery: A Case Report, J Stroke Cerebrovasc Dis, May;27(5)(May;27(5)), e78-e79, 20180501
  52. Iatrogenic Removal of the Intima in the Middle Cerebral Artery by a Stent Retriever: A Report of Two Cases., World Neurosurg, 203-208, 20181001
  53. A Case of Rapid Malignant Brain Swelling Subacutely After Reperfusion Therapy for Internal Carotid Artery Occlusion, World Neurosurg, 311-315, 20181001
  54. A Case of Subgaleal Hematoma after Minor Head Trauma Leading to the Diagnosis of von Willebrand Disease., No Shinkei Geka, 46(7), 629-631, 20180701
  55. ★, Age of donor of human mesenchymal stem cells affects structural and functional recovery after cell therapy following ischaemic stroke, J Cereb Blood Flow Metab, 38(7), 1199-1212, 20180701
  56. "Black butterfly" sign on T2*-weighted and susceptibility-weighted imaging: A novel finding of chronic venous congestion of the brain stem and spinal cord associated with dural arteriovenous fistulas, J Neurol Sci, 379, 64-68, 20170815
  57. Rapid Recanalization Using TrevoProVue through a 4.2 Fr Catheter without a Guiding Catheter via Transbrachial Approach A Case Report., NMC Case Rep J, 4(4), 97-99, 20170823
  58. A Case of Moyamoya Disease Associated with SAPHO Syndrome, No Shinkei Geka, 45(6), 533-539, 20170601
  59. Subacute lesion volume as a potential prognostic biomarker for acute ischemic stroke after intravenous thrombolysis, J Neurol Sci, 77-81, 20161015
  60. Point-by-point parent artery/sinus obliteration using detachable, pushable, 0.035-inch coils, Acta Neurochir (Wien), 158(11), 2089-2094, 20160101
  61. Acute stroke with major intracranial vessel occlusion: Characteristics of cardioembolism and atherosclerosis-related in situ stenosis/occlusion, J Clin Neurosci., 24-29, 20161001
  62. Significance of the Hemorrhagic Site for Recurrent Bleeding: Prespecified Analysis in the Japan Adult Moyamoya Trial., Stroke Jan, 47(1), 37-43, 20160101
  63. One Cause of Secondary Hypertension: Neurogenic Etiology, Circulation, 133(20), 1985-1986, 20160517
  64. ★, Communication of inwardly projecting neovessels with the lumen contributes to symptomatic intraplaque hemorrhage in carotid artery stenosis, J Neurosurg, 19, 1-8, 20150101
  65. Intraoperative Angiography Using Portable Fluoroscopy Unit in the Treatment of Vascular Malformation, Neurol Med Chir (Tokyo), 55(6), 505-509, 20150101
  66. Intra-arterial transplantation of low-dose stem cells provides functional recovery without adverse effects after stroke, Cell Mol Neurobiol, 35, 399-406, 20150101
  67. Microsurgical clipping for recurrent aneurysms after initial endovascular coil embolization., World Neurosurg, 83, 211-218, 20150101
  68. A Novel Method for Super-selective Coil Embolization Using An Extremely Soft Bare Coil through A Liquid Embolic Delivery Microcatheter, Neurol Med Chir (Tokyo)., 55, 605-609, 20150101
  69. A Ruptured Basilar Tip Aneurysm Showing Repeated Perianeurysmal Edema After Endovascular Coil Embolization, Neurol Med Chir (Tokyo), 55, 519-523, 20150101
  70. A Case of Neurofibromatosis Type 1 Complicated with Repeated Intracerebral Hemorrhage due to Quasi-Moyamoya Disease., J Stroke Cerebrovasc Dis, 24, 109-113, 20150101
  71. De Novo Vertebral Artery Dissection after Endovascular Trapping for Ruptured Dissecting Internal Carotid Artery Aneurysm, Neurol Med Chir (Tokyo), 55, 524-527, 20150101
  72. Cilostazol may prevent cardioembolic stroke in patients undergoing antiplatelet therapy, Neurol Res, Jul;37(7), 619-623, 20150101
  73. Cardiac diastolic dysfunction predicts in-hospital mortality in acute ischemic stroke with atrial fibrillation, J Neurol Sci., 15, 83-86, 20140101
  74. The rim pattern of meningioma on 3D FLAIR imaging: correlation with tumor-brain adhesion and histological grading,, Magn Reson Med Sci, 13, 251-260, 20140101
  75. Nationwide survey of decompressive hemicraniectomy for malignant middle cerebral artery infarction in Japan, World Neurosurg, 82, 1158-1163, 20140101
  76. A nationwide survey on unilateral moyamoya disease in Japan, Clin Neurol Neurosurg, 124, 1-5, 20140101
  77. Nationwide survey on quasi-moyamoya disease in Japan, Acta Neurochir (Wien), 156, 935-940, 20140101
  78. Usefulness of C-stopper coil for neurointervention., Neurol Med Chir (Tokyo), 47, 450-456, 20140101
  79. Impact of Aneurysm Locati Son on Cardiopulmonary Dysfunction after Subarachnoid Hemorrhage, The Journal of Stroke and Cerebrovascular Diseases, 23, 1795-1804, 20140101
  80. ★, Impact of Clipping versus Coiling on Postoperative Hemodynamics and Pulmonary Edema after Subarachnoid Hemorrhage Special Issue Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: Mechanism and Therapies, Clinical Study, 2014, 20140101
  81. ★, De Novo Ivy Sign Indicates Postoperative Hyperperfusion in Moyamoya Disease, Stroke, 45, 1488-1491, 20140101
  82. A case of iliac artery injury treated by covered stent during carotid artery stenting, Acta Neurochir (Wien), 156, 561-564, 20140101
  83. "Snake fang" sign without carotid stenosis on duplex ultrasonography indicates high risk of artery-to-artery embolic stroke, J Neuroimaging, 24, 407-410, 20140101
  84. Indocyanine Green Videoangiography for Assessment of Postoperative Hyperperfusion in Moyamoya Disease, Acta Neurochir (Wien), 156, 919-926, 20140101
  85. JAM Trial Investigators (Horie N as collaborators), Stroke, May;45(5), 1415-1421, 20140401
  86. A case of unilateral moyamoya disease suffered from intracerebral hemorrhage due to the rupture of cerebral aneurysm, which appeared seven years later, Surg Neurol Int, 4, 13-13, 20130101
  87. Measurement of Carotid Stenosis Using Duplex Ultrasonography with a Microconvex Array Transducer: A Validation with Cerebral Angiography, The Journal of Stroke and Cerebrovascular Diseases, 360-365, 20130101
  88. Intra-Arterial Cell Transplantation Provides Timing-Dependent Cell Distribution and Functional Recovery After Stroke, Stroke, 44, 720-726, 20130101
  89. ★, Assessment of carotid plaque stability based on the dynamic enhancement pattern in plaque components with multidetector CT angiography, Stroke, 43, 393-398, 20120101
  90. Incidence and clinical features of symptomatic cerebral hyperperfusion syndrome after vascular reconstruction, World Neurosurg, 78, 447-454, 20120101
  91. Selective coil embolization through flow-directed microcatheter for intracranial arteriovenous malformations, Acta Neurochir (Wien), 154, 989-991, 20120101
  92. New variant of persistent primitive olfactory artery associated with a ruptured aneurysm, Journal of Neurosurgery, 117, 26-28, 20120101
  93. Intra-arterial indocyanine green angiography in the management of spinal arteriovenous fistulae: technical case reports, Spine (Phila Pa 1976), 37, 264-267, 20120101
  94. Endovascular treatment of intractable bleeding from a traumatic pseudoaneurysm of the internal maxillary artery, Neuroradiol J, 25, 469-474, 20120101
  95. Aortic Dissection Complicated withFatal Cerebral Infarction: Case Report and Review of Literatures, Open Journal of Modem Neurosurgery, 2, 21-24, 20120101
  96. Clinical features and long-term follow-up of quasi-moyamoya disease in children, Pediatr Neurosurg, 47, 15-21, 20110101
  97. ★, "Brush Sign" on susceptibility-weighted MR imaging indicates the severity of moyamoya disease, AJNR Am J Neuroradiol, 32, 1697-1702, 20110101
  98. ★, Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair, Stem Cells, 29, 274-285, 20110101
  99. Long-term behavioral assessment of function in an experimental model for ischemic stroke, J Neurosci Methods, 196, 247-257, 20110101
  100. Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain, Brain, 134, 1777-1789, 20110101
  101. Detection of blood blister-like aneurysm and intramural hematoma with high-resolution magnetic resonance imaging, Journal of Neurosurgery, 115, 1206-1209, 20110101
  102. Cerebellar variant of posterior reversible encephalopathy syndrome (PRES) after coil embolization for the hemorrhagic dissecting aneurysm, Acta Neurochir (Wien), 153, 1135-1139, 20110101
  103. Positron emission tomography imaging of poststroke angiogenesis, Stroke, 40, 270-277, 20090101
  104. Efficacy of DynaCT digital angiography in the detection of the fistulous point of dural arteriovenous fistulas, AJNR Am J Neuroradiol, 30, 487-491, 20090101
  105. Long-term follow-up of endovascular coil embolization for cerebral aneurysms using three-dimensional time-of-flight magnetic resonance angiography, Neurol Res, 31, 674-680, 20090101
  106. Effects of oxygen concentration on the proliferation and differentiation of mouse neural stem cells in vitro, Cell Mol Neurobiol, 28, 833-845, 20080101
  107. Mouse model of focal cerebral ischemia using endothelin-1, J Neurosci Methods, 173, 286-290, 20080101
  108. Intracranial internal carotid artery stenosis with vulnerable plaques successfully treated by stenting under cerebral protection, Clin Neurol Neurosurg, 110, 1031-1034, 20080101
  109. Successful endovascular occlusion of an aneurysm of the cervical vertebral artery associated with neurofibromatosis-1, Acta Neurochir (Wien), 150, 847-848, 20080101
  110. Recanalization after endovascular occlusion of a dissecting aneurysm of the posterior cerebral artery-A case report and review of the literature-, Clin Neurol Neurosurg, 110, 411-415, 20080101
  111. Agenesis of the internal carotid artery with transcavernous anastomosis presenting with an anterior communicating artery aneurysm -A case report and review of the literature, Clin Neurol Neurosurg, 110, 622-626, 20080101
  112. Recurrence of the Cavernous Sinus Dural Arteriovenous Fistula at Adjacent Sinuses Following Repeated Transvenous Embolizations: Case Report and Literature Review, Radiation Medicine, 26, 431-437, 20080101
  113. Melatonin influences the proliferative and differentiative activity of neural stem cells, J Pineal Res, 42, 411-418, 20070101
  114. Giant thrombosed fusiform aneurysm at the basilar trunk successfully treated with endovascular coil occlusion following bypass surgery: A case report and review of the literature, Neurol Res, 29, 842-846, 20070101
  115. .Progressive Perianeurysmal Edema Induced after Endovascular Coil Embolization, Journal of Neurosurgery, 106, 916-920, 20070101
  116. Radiation-induced meningioma following prophylactic radiotherapy for acute lymphoblastic leukemia in childhood, Pediatr Neurosurg, 43, 36-41, 20070101
  117. Correlative association between circadian expression of mousePer2 gene and the proliferation of the neural stem cells, Neuroscience, 146, 494-498, 20070101
  118. 2D Thick-section MR digital subtraction angiography for the assessment of dural arteriovenous fistulas, AJNR Am J Neuroradiol, 27, 264-269, 20060101
  119. Monitoring of regional cerebral oxygenation by near-infrared spectroscopy in carotid arterial stenting: preliminary study, Neuroradiology, 47, 375-379, 20050101
  120. ★, Lowered glucose suppressed the proliferation and increased the differentiation of murine neural stem cells in vitro, FEBS Letters, 237-242, 20040101
  121. Ruptured aneurysm at the choroidal branch of the posterior inferior cerebellar artery: A case report and review of the literature, Surgical Neurology (World Neurosurgery), 540-544, 20030101
  122. Giant fusiform aneurysm in the middle cerebral artery presenting hemorrhage with different etiology., Journal of Neurosurgery, 391-396, 20030101
  123. Asymptomatic brain tumor detected at brain check-up, Neurologia Medico-Chirurgica, 41(41), 431-434, 20010101
  124. Stenting with GDC embolization for dissecting test restenosis of the internal carotid artery after balloon angioplasty, Acta Medica Nagasakinesia, 46(46), 73-76, 20010101

Publications such as books

  1. Neural Stem Cells, Cell therapy against cerebral stroke, Springer, 2017, Single work

Invited Lecture, Oral Presentation, Poster Presentation

  1. Assessemt of futile recanalization after endovascular thrombectomy for acute large vessel occlusion, Nobutaka Horie, 2022/08/21, Without Invitation, English, World Federation of Interventional and Therapeutic Neuroradiology, KYOTO
  2. How to use CERENOVUS Enterprise 2 -tips and tricks-, Nobutaka Horie, Jinjang Conference of Neuroendovascular Disease, 2018, With Invitation, English, Jinjang Conference of Neuroendovascular Disease, Nanjing, China
  3. Maximize endogenous recovery after stroke with endovascular stem cell therapy, Nobutaka Horie, Symposium III (Invited): Regenerative medicine in cerebral stroke (14th Korea-Japan Joint Conference on Surgery for Cerebral Stroke, With Invitation, English, 14th Korea-Japan Joint Conference on Surgery for Cerebral Stroke, Sapporo
  4. Stem Cell Transplantation for Experimental Stroke invited, Nobutaka Horie, The 1st joint symposium between Nagasaki University and Würzburg University, 2016, With Invitation, English, Nagasaki University and Würzburg University
  5. Stem Cell Transplantation Enhance BBB Integrity Through VEGF After Ischemic Stroke, Nobutaka Horie, BRI International Symposium 2012, 2012, With Invitation, English, BRI International Symposium, Niigata
  6. Vascular regenerative effects of human neural progenitor cells in the ischemic brain: a role in functional recovery, Nobutaka Horie, Shunsuke Ishizaka, Tonya Bliss,Gary K. Steinberg, Nobutaka Horie, Shunsuke Ishizaka, Tonya Bliss,Gary K. Steinberg, Nagasaki-Hallym Symposium, 2010, With Invitation, English, Hallym University Nagasaki University, Nagasaki
  7. Impact of Basal Ganglia Damage After Successful Endovascular Recanalization for Acute Ischemic Stroke Involving Lenticulostriate Arteries, Nobutaka HorieY. Morofuji, Y. Iki, Y. Matsunaga, E.Sadakata, T. Kanamoto, Y. Tateishi, T. Izumo, T. Anda, M. Morikawa, A. Tsujino, T. Matsuo, Nobutaka HorieY. Morofuji, Y. Iki, Y. Matsunaga, E.Sadakata, T. Kanamoto, Y. Tateishi, T. Izumo, T. Anda, M. Morikawa, A. Tsujino, T. Matsuo, World Federation of Interventional and Therapeutic Neuroradiology, 2019/10/21, Without Invitation, English, World Federation of Interventional and Therapeutic Neuroradiology, Napoli
  8. Impact of Basal Ganglia Damage After Successful Endovascular Recanalization for Acute Ischemic Stroke Involving Lenticulostriate Arteries, Nobutaka Horie, Yoichi Morofuji, Yusuke Iki, Eisaku Sadakata, Tadashi Kanamoto, Yohei Tateishi, Tsuyoshi Izumo, Takeo Anda, Minoru Morikawa, Akira Tsujino, and Takayuki Matsuo, Nobutaka Horie, Yoichi Morofuji, Yusuke Iki, Eisaku Sadakata, Tadashi Kanamoto, Yohei Tateishi, Tsuyoshi Izumo, Takeo Anda, Minoru Morikawa, Akira Tsujino, and Takayuki Matsuo, East Asian Conference of Neurointervention, 2019/07/10, Without Invitation, English, East Asian Conference of Neurointervention
  9. Impact of Mechanical Thrombectomy Device on the Thrombus Histology in Acute Embolic Stroke, Nobutaka Horie, Yoichi Morofuji, Eisaku Sadakata, Yohei Tateishi, Tsuyoshi Izumo, Minoru Morikawa, Akira Tsujino, Takayuki Matsuo, Nobutaka Horie, Yoichi Morofuji, Eisaku Sadakata, Yohei Tateishi, Tsuyoshi Izumo, Minoru Morikawa, Akira Tsujino, Takayuki Matsuo, ISC2017, 2017, Without Invitation, English, ISC, Houston
  10. Factors of Rebleeding After Aneurysmal Subarachnoid Hemorrhage Differ Depending on Clipping and Coiling oral presentation, Nobutaka Horie, Shuntaro Sato, Makio Kaminogo, Eisaku Sadakata, Tsuyoshi Izumo, Yoichi Morofuji, Takayuki Matsuo, Nobutaka Horie, Shuntaro Sato, Makio Kaminogo, Eisaku Sadakata, Tsuyoshi Izumo, Yoichi Morofuji, Takayuki Matsuo, WFITN 2017, 2017, Without Invitation, English, WFITN, Budapest
  11. Impact of Mechanical Thrombectomy Device on Thrombus Histology in Acute Embolic Stroke oral presentation, Nobutaka Horie, Eisaku Sadakata, Yoichi Morofuji, Tsuyoshi Izumo, Takayuki Matsuo, Nobutaka Horie, Eisaku Sadakata, Yoichi Morofuji, Tsuyoshi Izumo, Takayuki Matsuo, WFITN 2017, 2017, Without Invitation, English, WFITN, Budapest
  12. De Novo Ivy Sign Indicates Postoperative Hyperperfusion in Moyamoya Disease, Nobutaka Horie, Minoru Morikawa, Youichi Morofuji, Takeshi Hiu, Tsuyoshi Izumo, Kentaro Hayashi, Izumi Nagata, Nobutaka Horie, Minoru Morikawa, Youichi Morofuji, Takeshi Hiu, Tsuyoshi Izumo, Kentaro Hayashi, Izumi Nagata, International Stroke Conference 2016, 2016, Without Invitation, English, International Stroke Conference, Los Angeles
  13. Risk Factors Related to Aneurysmal Rebleeding after Subarachnoid Hemorrhage: Characteristics in the Pre-, Intra- and Postoperative Period Moderated Presentation, Nobutaka Horie, Makio Kaminogo, Tsuyoshi Izumo, Hajime Maeda, Yoichi Morofuji, Izumi Nagata, Takayuki Matsuo, Nobutaka Horie, Makio Kaminogo, Tsuyoshi Izumo, Hajime Maeda, Yoichi Morofuji, Izumi Nagata, Takayuki Matsuo, International Stroke Conference 2016, 2016, Without Invitation, English, International Stroke Conference, Los Angeles
  14. Acute stroke showing major intracranial vessel occlusion characteristics of cardioembolics and atherosclerosis related in situ stenosis/occlusion, East Asian Conference of Neurointervention 2016, 2016, Without Invitation, English, East Asian Conference of Neurointervention, Kobe
  15. Luminal Neovascular Sprouting with Inflammation Contributes to Symptomatic Intraplaque Hemorrhage in Carotid Stenosis, Nobutaka Horie, Minoru Morikawa, Youichi Morofuji,, Tsuyoshi Izumo, Kentaro Hayashi, Takayuki Matsuo, Izumi Nagata, Nobutaka Horie, Youichi Morofuji, Minoru Morikawa, Yohei Tateishi, Tsuyoshi Izumo, Kentaro Hayashi, Akira Tsujino, Izumi Nagata, International Stroke Conference, 2015/02/11, Without Invitation, English, International Stroke Conference, Nashville
  16. Indocyanine Green Videoangiography for Assessment of Postoperative Hyperperfusion in Moyamoya Disease moderated presentation, Nobutaka Horie, Minoru Morikawa, Youichi, Morofuji, HiuYuhtaka Fukuda, Kentaro Hayashi, Tsuyoshi Izumo, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Minoru Morikawa, Youichi, Morofuji, HiuYuhtaka Fukuda, Kentaro Hayashi, Tsuyoshi Izumo, Kazuhiko Suyama, Izumi Nagata, International Stroke Conference 2014, 2014, Without Invitation, English, International Stroke Conference, San Diego
  17. Impact of clipping versus coiling on postoperative hemodynamics and pulmonary edema after subarachnoid hemorrhage,, Nobutaka Horie, Mitsutoshi Iwaasa, Eiji Isotani, Shunsuke Ishizaka, Motohiro Sekino, Tsuyoshi Izumo, Kentaro Hayashi, Kazuhiko Suyama, Tooru Inoue, Izumi Nagata, on behalf of the SAH PiCCO Study Group, Nobutaka Horie, Mitsutoshi Iwaasa, Eiji Isotani, Shunsuke Ishizaka, Motohiro Sekino, Tsuyoshi Izumo, Kentaro Hayashi, Kazuhiko Suyama, Tooru Inoue, Izumi Nagata, on behalf of the SAH PiCCO Study Group, International Stroke Conference 2014,, 2014, Without Invitation, English, International Stroke Conference, San Diego
  18. Impact of the Type of Prior Antithrombotic Agents on Secondary Hemorrhagic Stroke: Location, Severity and Outcome, Nobutaka Horie, Makio Kaminogo, Tomohito Hirao, Masaaki Fukushima, Akira Izaki, Katsuharu Mori, Akira Shibayama, Wataru Haraguchi, Kiyoshi Shirakawa, Makoto Hirose, Hideaki Takahata, Akira Tsujino, Gohei So, Tsuyoshi Izumo, Kunihiko Nagasato, Izumi Nagata on behalf of Retrospective Study of Stroke Risk in Antithrombotic Therapy (RESTATE) Group,, Nobutaka Horie, Makio Kaminogo, Tomohito Hirao, Masaaki Fukushima, Akira Izaki, Katsuharu Mori, Akira Shibayama, Wataru Haraguchi, Kiyoshi Shirakawa, Makoto Hirose, Hideaki Takahata, Akira Tsujino, Gohei So, Tsuyoshi Izumo, Kunihiko Nagasato, Izumi Nagata on behalf of Retrospective Study of Stroke Risk in Antithrombotic Therapy (RESTATE) Group,, International Stroke Conference 2014, 2014, Without Invitation, English, International Stroke Conference, San Diego
  19. Postoperative Hemodynamics is Different between Clipping and Coiling after Aneurismal Subarachnoid Hemorrhage -A Multicenter Prospective Cohort Study, International, Nobutaka Horie, Mitsutoshi Iwaasa, Eiji Isotani, Shunsuke Ishizaka, Tooru Inoue, Izumi Nagata, Nobutaka Horie, Mitsutoshi Iwaasa, Eiji Isotani, Shunsuke Ishizaka, Tooru Inoue, Izumi Nagata, International Stroke Conference 2013, 2013, Without Invitation, English, International Stroke Conference, Hawaii
  20. Indocyanine Green Videoangiography for the Assessment of Postoperative Hyperperfusion in Moyamoya Disease, Nobutaka Horie, Minoru Morikawa, Yuhtaka Fukuda, Kentaro Hayashi, Tsuyoshi Izumo, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Minoru Morikawa, Yuhtaka Fukuda, Kentaro Hayashi, Tsuyoshi Izumo, Kazuhiko Suyama, Izumi Nagata, The 3rd International Moyamoya meeteing,, 2013, Without Invitation, English, Sapporo
  21. Characteristics of the Hemorrhagic Event in the Patients Taking Different Types of Antiplatelet Agent for the Prevention of the Secondary Stroke, Nobutaka Horie, Makio Kaminogo, Tomohito Hirao, Masaaki Fukushima, Akira Izaki, Katsuharu Mori, Akira Shibayama, Wataru Haraguchi, Kiyoshi Shirakawa, Makoto Hirose, Hideaki Takahata, Akira Tsujino, Gohei So, Tsuyoshi Izumo, Kunihiko Nagasato, Izumi Nagata,, Nobutaka Horie, Makio Kaminogo, Tomohito Hirao, Masaaki Fukushima, Akira Izaki, Katsuharu Mori, Akira Shibayama, Wataru Haraguchi, Kiyoshi Shirakawa, Makoto Hirose, Hideaki Takahata, Akira Tsujino, Gohei So, Tsuyoshi Izumo, Kunihiko Nagasato, Izumi Nagata,, The 6th Korea-Japan Joint Stroke Conference, 2013, Without Invitation, English, Osaka
  22. Decreased glomerular filtration rate has a greater impact on the outcome in hemorrhagic stroke than in ischemic stroke in the acute stage, Nobutaka Horie, Shunsuke Ishizaka, Youhei Tateishi , Kentaro Hayashi , Akira Tsujino, Kazuhiko Suyama , Izumi Nagata, Nobutaka Horie, Shunsuke Ishizaka, Youhei Tateishi , Kentaro Hayashi , Akira Tsujino, Kazuhiko Suyama , Izumi Nagata, International Stroke Conference 2012, 2012, Without Invitation, English, International Stroke, New Orleans
  23. Endovascular stem cell transplantation is promising for the post-stroke functional recovery, Nobutaka Horie, Shunsuke Ishizaka, Katsuya Satoh, Noriyuki Nishida, Izumi Nagata, Nobutaka Horie, Shunsuke Ishizaka, Katsuya Satoh, Noriyuki Nishida, Izumi Nagata, The 10th meeting of Asian Australasian Federation of Interventional and Therapeutic Neuroradiology AAFITN 2012, 2012, Without Invitation, English, Asian Australasian Federation of Interventional and Therapeutic Neuroradiology, nagoya
  24. Significance of the Thrombus Component as a Prediction for the Malignant Middle Cerebral Artery Infarction, Nobutaka Horie, Minoru Morikawa, Yohhei Tateishi, Tujino Akira, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Minoru Morikawa, Yohhei Tateishi, Tujino Akira, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, Asia Pacific Stroke Conference 2012, 2012, Without Invitation, English, Asia Pacific Stroke, tokyo
  25. Delayed absorption of the contrast media in CT angiography indicates plaque stability in carotid stenosis, Nobutaka Horie, Minoru Morikawa, Shunsuke Ishizaka, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Minoru Morikawa, Shunsuke Ishizaka, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, International Stroke Conference 2011, 2011, Without Invitation, English, International Stroke, Los Angeles
  26. Brush Sign on Susceptibility Weighted MR Imaging Indicates the Severity of Moyamoya Disease, Without Invitation, Japanese
  27. Vascular regenerative effects of human neural progenitor cells in the ischemic brain: a role in functional recovery, Nobutaka Horie, Tonya Bliss, Kuniyasu Niizuma, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Stephen Huhn, and Gary K. Steinberg, Nobutaka Horie, Tonya Bliss, Kuniyasu Niizuma, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Stephen Huhn, and Gary K. Steinberg, International Stroke Conference 2010, 2010, Without Invitation, English, International Stroke, San Antonio
  28. Careful follow up is mandatory after endovascular PTA/Stenting for Takayasu arteritis: report of three cases and review of the literature, Nobutaka Horie, Kentaro Hayashi, Hideaki Takahata, Minoru Morikawa, Gohei So, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Kentaro Hayashi, Hideaki Takahata, Minoru Morikawa, Gohei So, Kazuhiko Suyama, Izumi Nagata, East Asian Conference of Neurointervention 2010, 2010, English
  29. Outcome and early prognosis of treated aneurismal subarachnoid hemorrhage in a defined population -Nagasaki SAH registry-,, Nobutaka Horie, Makio, Kaminogo, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Makio, Kaminogo, Kentaro Hayashi, Kazuhiko Suyama, Izumi Nagata, The 10th Korean and Japanese Friendship Conference on Surgery for Cerebral Stroke, 2010, Without Invitation, English, Nagasaki
  30. Transplantation of human neural progenitor/stem cells enhances neovascularization and blood brain barrier integrity after stroke in rat, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg, International Stroke Conference 2009, 2009, Without Invitation, English, International Stroke, San Diego
  31. Transplanted human neural progenitor cells enhance endogenous dendritic plasticity and axonal sprouting after stroke in ra, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg, International Stroke Conference 2009, 2009, Without Invitation, English, International Stroke, San Diego
  32. Transplantation of human neural progenitor/stem cells enhances neovascularization and blood brain barrier integrity after stroke, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill, Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg, American Association of Neurological Surgeons 2009, 2009, Without Invitation, English, American Association of Neurological Surgeons, San Diego
  33. Transplanted human neural progenitor cells enhance endogenous dendritic plasticity and axonal sprouting after stroke in rat, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg, American Association of Neurological Surgeons 2009, 2009, Without Invitation, English, American Association of Neurological Surgeons, San Diego
  34. Transplantation of human neural progenitor cells after stroke, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg,, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg,, WFNS World Federation of Neurosurgical Societies, 2009, Without Invitation, English, Neurosurgical Societies, Boston
  35. Vascular regenerative effects of human neural progenitor cells in the ischemic brain: a role in functional recovery?, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg,, Nobutaka Horie, Robert H Andres, Hadar Keren-Gill, William Slikker, GuoHua Sun, Erin McMillan, Clive Svendsen, Tonya Bliss, and Gary K. Steinberg,, WFNS World Federation of Neurosurgical Societies, 2009, Without Invitation, English, Neurosurgical Societies, Boston
  36. PTA/Stenting for Takayasu arteritis; is this durable option?, Nobutaka Horie, Kentaro Hayashi, Hideaki Takahata, Minoru Morikawa, Gohei So, Kazuhiko Suyama, Izumi Nagata, Nobutaka Horie, Kentaro Hayashi, Hideaki Takahata, Minoru Morikawa, Gohei So, Kazuhiko Suyama, Izumi Nagata, The 11th Kyushu and Young-Honam Neurosurgical Joint meeting, Gwangju, 2009, Without Invitation, English, Fukuoka University, Korea
  37. Ischemia-induced Angiogenesis Is Enhanced By hCNS-SCn Transplantation, Nobutaka Horie, Tonya Bliss, Hideo Shichinohe, Theo Palmer, Gary K Steinberg, Nobutaka Horie, Tonya Bliss, Hideo Shichinohe, Theo Palmer, Gary K Steinberg, International Stroke Conference 2008, 2008, Without Invitation, English, International Stroke, New Orleans
  38. Mouse model of focal cerebral ischemia using endothelin-1, Nobutaka Horie, Anne-Lise Maag, Scott A. Hamilton, Hideo Shichinohe, Tonya M. Blissa , Gary K. Steinberg, Nobutaka Horie, Anne-Lise Maag, Scott A. Hamilton, Hideo Shichinohe, Tonya M. Blissa , Gary K. Steinberg, American Association of Neurological Surgeons (AANS) Annual meeting, 2008, Without Invitation, English, American Association of Neurological Surgeons (AANS), Chicago
  39. Transplantation of human neural progenitor cells enhances endogenous angiogenesis and dendritic plasticity after stroke, Nobutaka Horie, William Slikker, Hadar Keren-Gill, Guohua Sun, Marta Pereira, Tonya Bliss, Clive Svendson, Erin McMillan, Gary Steinberg,, Nobutaka Horie, William Slikker, Hadar Keren-Gill, Guohua Sun, Marta Pereira, Tonya Bliss, Clive Svendson, Erin McMillan, Gary Steinberg,, Annual Meeting of Congress of Neurological Surgeons, 2008, Without Invitation, English, Congress of Neurological Surgeons, Orlando
  40. Transplantation of human neural progenitor cells enhances neovascularization and blood brain barrier integrity after stroke in rat, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill,Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg,, Nobutaka Horie, Marta P. Pereira, GuoHua Sun, Hadar Keren-Gill,Kewen Jiang, Angelo Encarnacion, Mehrdad Shamloo, Tonya Bliss, and Gary K. Steinberg,, Society for Neuroscience (J Neuroscience) Annual Meeting 2008, 2008, Without Invitation, English, Neuroscience, Washington DC
  41. Ischemia-induced angiogenesis is enhanced by human CNS stem cell transplantation, Nobutaka Horie, Tonya Bliss, Anne-Lise Maag, Theo Palmer and Gary Steinberg, Nobutaka Horie, Tonya Bliss, Anne-Lise Maag, Theo Palmer and Gary Steinberg, Annual Meeting of Congress of Neurological Surgeons (Neurosurgery) 2007, 2007, Without Invitation, English, Congress of Neurological Surgeons, San Diego
  42. Human neural stem cell therapy for stroke: a role in neovascularization, Nobutaka Horie, Tonya Bliss, Anne-Lise Maag, Theo Palmer and Gary Steinberg, Nobutaka Horie, Tonya Bliss, Anne-Lise Maag, Theo Palmer and Gary Steinberg, Society for Neuroscience (J Neuroscience) Annual Meeting 2007, 2007, Without Invitation, English, Society for Neuroscience, San Diego

Awards

  1. 2009/05/02, The 77th American Association of Neurological SurgeonsThird Place Award in Cerebrovascular, American Association of Neurological Surgeons, Transplanted Human Neural Progenitor Cells Enhance Endogeneous Dendritic Plasticity And Axonal Sprouting After Stroke in Rat
  2. 2009/02/18, Top Abstract Award, International Stroke Conference, Transplanted Human Neural Progenitor Cells Enhance Endogeneous Dendritic Plasticity And Axonal Sprouting After Stroke in Rat
  3. 2008/04/26, The 76th American Association of Neurological SurgeonsThird Place Award in Cerebrovascular, American Association of Neurological Surgeons, Mouse Model of Focal Ischemia Using Enfdothelin-1