Tatsuya Ueki
Last Updated :2025/04/03
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Associate Professor
- Web Site
- E-mail
- ueki
hiroshima-u.ac.jp
- Self-introduction
- I have been conducting molecular and cellular research such as discovery of proteins and genes related to vanadium accumulation mechanism of marine animal ascidians, biochemical elucidation of accumulation / reduction processes, and isolation and identification of symbiotic bacteria related to vanadium accumulation.
Basic Information
Academic Degrees
- Doctor of Science, Kyoto University
- Master of Science, Kyoto University
Educational Activity
- [Bachelor Degree Program] School of Science : Biological Sciences : Biology
- [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Basic Biology
- [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Basic Biology
Research Fields
- Biology;Basic biology;Animal physiology / Animal behavior
Research Keywords
- physiology/biochemistry
- metal accumulation / rare metal recovery /waste recycling
- metal-binding proteins / membrane metal transporters / metal reductases
- vanadium
- marine invertebrates / tunicates / ascidians / costal habitats
- marine bacteria / metal-accumulating bacteria
Affiliated Academic Societies
- Zoological Society of Japan, 1991
- Japanese Society for Marine Biotechnology, 1998
- Japanese Society for Comparative Biochemistryu and Physiology, 1998
Educational Activity
Course in Charge
- 2025, Liberal Arts Education Program1, 2Term, Introductory Seminar for First-Year Students
- 2025, Undergraduate Education, 2Term, Advanced Biology
- 2025, Undergraduate Education, Second Semester, Seminar for Molecular Physiology
- 2025, Undergraduate Education, First Semester, Special Study for Graduation
- 2025, Undergraduate Education, Second Semester, Special Study for Graduation
- 2025, Undergraduate Education, First Semester, Summer Course for Marine Biology A
- 2025, Undergraduate Education, First Semester, Summer Course for Marine Biology B
- 2025, Undergraduate Education, First Semester, Marine Biological Course
- 2025, Undergraduate Education, Year, New marine course for marine biological education
- 2025, Undergraduate Education, First Semester, Shimanami Kaido Marine Biology Course
- 2025, Undergraduate Education, Second Semester, Shimanami Kaido Marine Biology Course
- 2025, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Basic Biology
- 2025, Graduate Education (Master's Program) , 2Term, Molecular Physiology
- 2025, Graduate Education (Master's Program) , First Semester, Exercises in Basic Biology A
- 2025, Graduate Education (Master's Program) , Second Semester, Exercises in Basic Biology B
Research Activities
Academic Papers
- Isolation of cDNA clones for epidermis-specific genes of the ascidian embryo, Development, Growth and Differentiation, 33(6), 579-586, 19910401
- Autonomy of expression of epidermis-specific genes in the ascidian embryo, Developmental Biology, 164, 207-218, 19940401
- An ascidian homolog of SEC61 is expressed predominantly in epidermal cells of the emnbryo, Developmental Biology, 165, 185-192, 19940401
- Spatiotemporal expression of eight epidermis-specific genes in the ascidian embryo, Zoological Science, 13, 699-709, 19960401
- Peripheral development of cranial nerves in a cyclostome, Lampetra japonica- Morphological distribution of nerve branches and the vertebrate body plan, Journal of Comparative Neurology, 384, 483-500, 19970401
- Early development of the peripheral nervous system in a lancelet species., Journal of Comparative Neurology, 415-425, 19980401
- Stereotyped axonal bundle formation and neuromeric patterns in embryos of a cyclostome, Lampetra japonica, Journal of Comparative Neurology, 391, 99-114, 19980401
- Rostral truncation of a cyclostome, Lampetra japonica, induced by all-trans retinoic acid defines the head/trunk interface of the vertebrate body, Developmental Dynamics, 211, 35-51, 19980401
- ★, Otx cognates in a lamprey, Lampetra japonica, Development Genes and Evolution, 208, 223-228, 19980401
- A 100-kDa antigen recognized by a newly prepared monoclonal antibody specific to the vanadocytes of the vanadium-rich ascidian, Ascidia sydneiensis samea, is glycogen phosphorylase, Zoological Science, 15, 815-821, 19980401
- Isolation of cDNAs encoding subunits A and B of the vacuolar-type ATPase from the vanadium-rich ascidian, Ascidia sydneiensis samea, Zoological Science, 15, 823-829, 19980401
- Development of cephalic neural crest cells in embryos of Lampetra japonica, with special reference to the evolution of the jaw, Developmental Biology, 207, 287-308, 19990401
- Direct reduction from vanadium(V) to vanadium(IV) by NADPH in the presence of EDTA. A Consideration of the reduction and accumulation of vanadium in the ascidian blood cells., Journal of Inorganic Biochemistry, 77, 157-161, 19990401
- ★, Exclusive expression of transketolase in the vanadocytes of the vanadium-rich ascidian, Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1494(1-2), 83-90, 20001115
- Subunit C of the vacuolar-type ATPase from the vanadium-rich ascidian Ascidia sydneiensis samea rescued the pH sensitivity of yeast vma5 mutants, MARINE BIOTECHNOLOGY, 3(4), 316-321, 200107
- Conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution, Journal of Experimental Zoology, 291, 68-84, 20010401
- Isolation of Dlx and Emx gene cognates in an agnathan species, Lampetra japonica, and their expression patterns during embryonic and larval development: Conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution, JOURNAL OF EXPERIMENTAL ZOOLOGY, 291(1), 68-84, 20010415
- Scanning X-ray microscopy of living and freeze-dried blood cells in two vanadium-rich ascidian species, Phallusia mammillata and Ascidia sydneiensis samea, ZOOLOGICAL SCIENCE, 19(1), 27-35, 200201
- Expressed sequence tag analysis of blood cells in the vanadium-rich ascidian, Ascidia sydneiensis samea - A survey of genes for metal accumulation, ZOOLOGICAL SCIENCE, 19(9), 1001-1008, 200209
- Vanadocytes, cells hold the key to resolving the highly selective accumulation and reduction of vanadium in ascidians, MICROSCOPY RESEARCH AND TECHNIQUE, 56(6), 421-434, 20020315
- Molecular biological approaches to the accumulation and reduction of vanadium by ascidians, COORDINATION CHEMISTRY REVIEWS, 237(1-2), 41-51, 200302
- X-ray microscopy in Ritsumeikan Synchrotron Radiation Center, JOURNAL DE PHYSIQUE IV, 104, 57-61, 200303
- Local distribution of vanadium in the living blood cells of ascidians by fluorescence scanning X-ray microscopy ID21 at ESRF, JOURNAL DE PHYSIQUE IV, 104, 333-336, 200303
- Chloride channel in vanadocytes of a vanadium-rich ascidian Ascidia sydneiensis samea, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 136(1), 91-98, 200309
- Bioaccumulation of copper ions by Escherichia coli expressing vanabin genes from the vanadium-rich ascidian Ascidia sydneiensis samea, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69(11), 6442-6446, 200311
- ★, Vanadium-binding proteins (vanabins) from a vanadium-rich ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1626(1-3), 43-50, 20030415
- Vanadium-binding protein in a vanadium-rich ascidian Ascidia sydneiensis samea: CW and pulsed EPR studies, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 125(21), 6352-6353, 20030528
- Novel vanadium-binding proteins (vanabins) identified in cDNA libraries and the genome of the ascidian Ciona intestinalis, BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1630(2-3), 64-70, 20031130
- Expressed sequence tag analysis of vanadocytes in a vanadium-rich Ascidian, Ascidia sydneiensis samea, MARINE BIOTECHNOLOGY, 6(2), 165-174, 200403
- 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy, JOURNAL OF IMMUNOLOGY, 172(10), 6373-6381, 20040515
- Toxicity and bioaccumulation of hexavalent chromium in green paramecium, Paramecium bursaria, JOURNAL OF HEALTH SCIENCE, 51(6), 676-682, 200512
- Solution structure of vanabin2, a vanadium(IV)-binding protein from the vanadium-rich ascidian Ascidia sydneiensis samea, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 127(12), 4216-4222, 20050330
- VanabinP, a novel vanadium-binding protein in the blood plasma of an ascidian, Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1730(3), 206-214, 20050925
- Glutathione transferases with vanadium-binding activity isolated from the vanadium-rich ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760(3), 495-503, 200603
- Selective metal binding by Vanabin2 from the vanadium-rich ascidian, Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1760(7), 1096-1101, 200607
- Localization of Vanabins, vanadium-binding proteins, in the blood cells of the vanadium-rich ascidian, Ascidia sydneiensis samea, ZOOLOGICAL SCIENCE, 23(10), 909-915, 200610
- Identification of Vanabin-interacting protein 1 (VIP1) from blood cells of the vanadium-rich ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(6), 951-957, 200706
- Reduction of vanadium(V) to vanadium(IV) by NADPH, and vanadium(IV) to vanadium(III) by cysteine methyl ester in the presence of biologically relevant ligands, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(8), 1212-1218, 200708
- Metal binding ability of glutathione transferases conserved between two animal species, the vanadium-rich ascidian Ascidia sydneiensis samea and the schistosome Schistosoma japonicum, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1770(9), 1413-1418, 200709
- Characterization of a novel vanadium-binding protein (VBP-129) from blood plasma of the vanadium-rich ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1780(2), 256-263, 200802
- Sequence variation of Vanabin2-like vanadium-binding proteins in blood cells of the vanadium-accumulating ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1780(7-8), 1010-1015, 200807
- A novel vanadium reductase, Vanabin2, forms a possible cascade involved in electron transfer, BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1794(4), 674-679, 200904
- Identification and biochemical analysis of a homolog of a sulfate transporter from a vanadium-rich ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1790(10), 1295-1300, 200910
- Characterization of vanadium-binding sites of the vanadium-binding protein Vanabin2 by site-directed mutagenesis, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1790(10), 1327-1333, 200910
- Advances in research on the accumulation, redox behavior, and function of vanadium in ascidians., Biomolecular Concepts, 1(1), 97-107, 20100501
- ★, A novel vanadium transporter of the Nramp family expressed at the vacuole of vanadium-accumulating cells of the ascidian Ascidia sydneiensis samea, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1810(4), 457-464, 201104
- Molecular mechanism of the transport and reduction pathway of vanadium in ascidians, COORDINATION CHEMISTRY REVIEWS, 255(19-20), 2249-2257, 201110
- Identification of a Novel Vanadium-binding Protein by EST Analysis on the Most Vanadium-rich Ascidian, Ascidia gemmata, MARINE BIOTECHNOLOGY, 14(2), 143-154, 201204
- Differential gene regulation by V-IV and V-V ions in the branchial sac, intestine, and blood cells of a vanadium-rich ascidian, Ciona intestinalis, BIOMETALS, 25(5), 1037-1050, 201210
- ★, Metal-binding domains and the metal selectivity of the vanadium(IV)-binding protein VBP-129 in blood plasma, JOURNAL OF INORGANIC BIOCHEMISTRY, 116, 70-76, 201211
- Metal ion selectivity of the vanadium(V)-reductase Vanabin2, DALTON TRANSACTIONS, 42(33), 11921-11925, 2013
- Participation of thioredoxin in the V(V)-reduction reaction by Vanabin2, BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1840(11), 3238-3245, 201411
- Role of cysteine residues in the V(V)-reductase activity of Vanabin2, INORGANICA CHIMICA ACTA, 420, 47-52, 20140824
- Vanadium accumulation in ascidians: A system overview, Coordination Chemistry Review, 301, 300-308, 20151001
- Bioaccumulation of vanadium by vanadium-resistant bacteria isolated from the intestine of Ascidia sydneiensis samea, Marine Biotechnology, 18(3), 359-371, 20160601
- Vanadium-binding ability of nucleoside diphosphate kinase from vanadium-rich fan worm, Pseudopotamilla occelata, Zoological Science, 33(3), 266-271, 20160601
- Structural and mass spectrometric imaging analyses of adhered tunic and adhesive projections of solitary ascidians, Zoological Science, 35, 535-548, 20181201
- ★, Symbiotic bacteria associated with ascidian vanadium accumulation identified by 16S rRNA amplicon sequencing, Marine Genomics, 43, 33-42, 20190201
- A draft genome assembly of the acoel flatworm Praesagittifera naikaiensis, GigaDB Datasets, 8(4), 1-8, 20190401
- Mechanism of vanadium accumulation and possible function of vanadium in underwater adhesion in ascidians., AIP Conference Proceedings, 2120(1), 020001, 20190703
- Xenacoelomorph-specific Hox peptides: Insights into the phylogeny of acoels, nemertodermatids, and xenoturbellids., Zoological Science, 36(5), 395-404, 20191001
- Characterization of vanadium of biological origin for possible applications in physics experiments, Journal of Environmental Radioactivity, 225, 106426, 20201201
- The acidic amino acid-rich C-terminal domain of VanabinX enhances reductase activity, attaining 1.3- to 1.7-fold vanadium reduction., Biochemistry and Biophysics Reports, 32, 101349, 20221201
- Concomitant downregulation of neuropeptide genes in a marine snail with consecutive sexual maturation after a nuclear disaster in Japan, FRONTIERS IN ENDOCRINOLOGY, 14, 20230310
- Vanadium Accumulation and Reduction by Vanadium-Accumulating Bacteria Isolated from the Intestinal Contents of Ciona robusta, MARINE BIOTECHNOLOGY, 26(2), 338-350, 20240401
- Cell-wide arrangement of Golgi/RE units depends on the microtubule organization, Cell Structure and Function, 20241003
Publications such as books
- 2007/08, Genes and proteins involved in vanadium accumulation by ascidians , 2007, 08, Scholarly Book, Joint work, 448
- 2007/12, Vanadium-protein interaction inferred from the studies on vanadium-binding proteins in ascidians , 2007, 12, Scholarly Book, Joint work, 999
- 2012/01, High levels of vanadium in ascidians, in Vanadium: biochemical and molecular biological approaches (H. Michibata, ed.), Springer-Verlag, 2012, 01, Scholarly Book, Cocompilation, 9789400709126, 228
- 2016, Plants, Pollutants and Remediation (Chapter), Vanadium in the Environment and Its Bioremediation, Springer, 2016, 2016, Scholarly Book, Single work, 英語, T. Ueki, 978-94-017-7194-8, 418
- 2020/02/01, Marine Ecology: Current and Future Developments Vol. 1 - Monitoring Artificial Materials and Microbes in Marine Ecosystems, Isolation of Vanadium-Accumulating or Reducing Bacteria from Ascidians and Their Functional Analysis, Bentham Books, 2020, 2020, Scholarly Book, Joint work, English, Tatsuya Ueki, Tri Kustono Adi, Romaidi, 978-981-14-3723-6, 281, 14
Invited Lecture, Oral Presentation, Poster Presentation
- The identification and analyses of the vacuolar-type proton ATPase in the vanadocytes of the ascidian Ascidia sydneiensis samea., 1999, Without Invitation, English
- Metal ion selectivity and affinity of wild type and mutant Vanabin2., Tatuya Ueki, The 5th International Vanadium Symposium, 2006/09, With Invitation, English
- Molecular mechanism of the transport and reduction pathway of vanadium in ascidians., Tatsuya Ueki, The 7th International Vanadium Symposium, 2010/10, With Invitation, English
- Differential Contribution of Vanabins as Vanadium Reductases on the reduction of V(V) to V(IV) in blood cells of an ascidian Ascidia sydneiensis samea, Tatsuya Ueki, The 8th International Vanadium Symposium, 2012/08, With Invitation, English, Washington D.C.
- Vanadium Accumulation in Ascidians: An Overview as a System, Tatsuya Ueki, The 9th International vanadium Symposium, 2014/06, With Invitation, English, Padova
- Vanadium Accumulation and Reduction in Ascidians: Contribution of symbiotic bacteria, Tatsuya Ueki ; Taichi Maeshige ; Toshihiro Hino ; Tri Kustono Adi ; Romaidi, The 10th International vanadium Symposium, 2016/11/06, With Invitation, English, Taipei
- Genetic Mechanism of Vanadium Accumulation and Possible Function of Vanadium in Underwater Adhesion in Ascidians, Tatsuya Ueki, 2018/11/08, With Invitation, English, International Vanadium Symposium, Montevideo (Uruguay)
- Mechanism of Vanadium Accumulation and Possible Function of Vanadium in Underwater Adhesion in Ascidians, Tatsuya Ueki, International Conference on Biology and Applied Science (ICOBAS), 2019/03/20, With Invitation, English, Biology Department, UIN Maulana Malik Ibrahim Malang., Malang, Indonesia
Awards
- 2013/06/01, Best Article Award for Marine Biotechnology 2013, Japanese Society for Marine Biotechnology, Identification of a Novel vanadium-binding Proteins by EST Analysis on the Most vanadium-Rich Ascidian, Ascidia gemmata
- 2020/09/04, Fujii Award, Zoological Society of Japan, Xenacoelomorph-Specific Hox Peptides: Insights into the Phylogeny of Acoels, Nemertodermatids, and Xenoturbellids
- 2020/09/04, Zoological Science Award, Zoological Society of Japan, Xenacoelomorph-Specific Hox Peptides: Insights into the Phylogeny of Acoels, Nemertodermatids, and Xenoturbellids
Social Activities
History as Committee Members
- Committee Member, 2020/09, 2022/09, Zoological Society of Japan
- International Advisory Board, 2017/01/01, 2025/12/31, Internatinal Vanadium Symposium
Organizing Academic Conferences, etc.
- The Seventh International Symposium on the Chemistry and Biological Chemistry of Vanadium, Secretary for general Affairs, 2010/10, 2010/10
Other Social Contributions
- Visiting lecture, Biotechnology and biomimetics: lessons from marine animals, University of Brawijaya (UB), 2014/11/10, 2014/11/10, Malang, Indonesia, Lecturer, Visiting lecture, Graduate students
- Visiting Lecture, Biotechnology and biomimetics: lessons from marine animals, State Islamic University of Malang (UIN), 2014/11/11, 2014/11/11, Malang, Indonesia, Lecturer, Visiting lecture, College students
- Visiting Lecture, Recent Advance of Study on Vanadium Accumulation: Biochemistry, Molecular and Physiological Work, 2017/03/27, 2017/03/27, Malang, Indonesia, Lecturer, Visiting lecture, College students
- Visiting Lecture, Recent Advance of Study on Vanadium Accumulation: Biochemistry, Molecular and Physiological Work, University of Brawijaya (UB), 2017/03/28, 2017/03/28, Malang, Indonesia, Lecturer, Visiting lecture, Graduate students
- Visiting Lecture, Recent Advance of Study on Vanadium Accumulation: Biochemistry, Molecular and Physiological Work, State Islamic University of Surabaya (UISB), 2017/03/30, 2017/03/30, Surabaya, Indonesia, Lecturer, Visiting lecture, College students
- Visiting Lecture, Vanadium in Ascidians: Molecular and Cellular Mechanism of Accumulation and Possible Function of Vanadium., State Islamic University of Malang (UIN Malang), 2018/03/26, 2018/03/26, Malang, Indonesia, Lecturer, Visiting lecture, College students
- Visiting Lecture, Ascidians: Its Unique Physiological Features and the Biotechnological and Biomimetic Application., IAIN Tulungagung, 2018/03/28, 2018/03/28, Tulungagung, Indonesia, Lecturer, Visiting lecture, College students
- Visiting Lecture, Mechanism of Vanadium Accumulation in Ascidians, IAIN Tulugangung, 2019/03/18, 2019/03/18, Tulungagung, Indonesia
- visiting lecture, Molecular and Cellular Mechanism of Accumulation and Possible Function of Vanadium, State Islamic University, Malang, 2020/11/26, 2020/11/26, ZOOM, Lecturer, Visiting lecture, Graduate students