YUKIO TAKESHIMA

Last Updated :2024/07/04

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Professor
Web Site
https://pathology.hiroshima-u.ac.jp/index-en.html
E-mail
ykotakehiroshima-u.ac.jp
Self-introduction
We purse a technique for more precise & rapid pathogical diagnosis by fusion of pathological morphology and molecular biology. Among various diseases, we are making efforts of novel markes detection for accurate pathological malignant mesotheliomas related asbestos-exposure.

Basic Information

Major Professional Backgrounds

  • 2000/04/07, 2012/06/30, Hiroshima University, Assistant Professor
  • 1991/04/01, 1995/03/31, Hiroshima University, Research Associate
  • 1995/04/01, 1995/04/30, Hiroshima University, Research Associate
  • 1995/05/01, 2000/03/31, Hiroshima University, Lecturer
  • 2012/07/01, 2019/03/31, Dept of Pathology, Institutes of Biomedical & Health Sciences, Professor
  • 2019/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Professor

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Medicine : Program of Medicine : Medicine
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences : Program of Biomedical Science
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Medicine

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Basic medicine;Human pathology

Research Keywords

  • Pathology
  • Environmental Carcinogenesis
  • Occupational cancer
  • mesothelioma
  • Lung cancer
  • molecular biology
  • Pathological Diagnosis
  • Autopsy
  • Digital pathology

Affiliated Academic Societies

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 2Term, Peace Messages from "Kasumi Campus"
  2. 2024, Undergraduate Education, Second Semester, Clinical Pathology
  3. 2024, Undergraduate Education, 2Term, Introduction for medical research
  4. 2024, Undergraduate Education, Intensive, Practice for medical research
  5. 2024, Undergraduate Education, Intensive, Practice of Medicine I
  6. 2024, Undergraduate Education, Intensive, Practice of Medicine II
  7. 2024, Undergraduate Education, First Semester, General Pathology
  8. 2024, Undergraduate Education, First Semester, Pathology
  9. 2024, Undergraduate Education, First Semester, Pathology
  10. 2024, Undergraduate Education, Intensive, Pathology
  11. 2024, Undergraduate Education, First Semester, Outline of Pathology
  12. 2024, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  13. 2024, Graduate Education (Master's Program) , First Semester, Seminar
  14. 2024, Graduate Education (Master's Program) , Second Semester, Seminar
  15. 2024, Graduate Education (Master's Program) , First Semester, Research
  16. 2024, Graduate Education (Master's Program) , Second Semester, Research
  17. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  18. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  19. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  20. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  21. 2024, Graduate Education (Master's Program) , Second Semester, Pathologic Basis of Diseases
  22. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Pathology
  23. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Pathology
  24. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Pathology
  25. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Pathology

Research Activities

Academic Papers

  1. SPARC Is a Novel Positive Immunohistochemical Marker of Epithelioid Mesothelioma to Differentiate It From Lung Adenocarcinoma and/or Squamous Cell Carcinoma, AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 48(2), 140-149, 202402
    Link to Paper Search Results by DOI
  2. miR-142-3p Suppresses Invasion and Adhesion of Mesothelioma Cells by Downregulating ITGAV, PATHOBIOLOGY, 90(4), 270-280, 202308
    Link to Paper Search Results by DOI
  3. FOXM1 Promotes Mesothelioma Cell Migration and Invasion via Activation of SMAD Signaling, ANTICANCER RESEARCH, 43(9), 3961-3968, 202309
    Link to Paper Search Results by DOI
  4. Downregulation of lncRNA PVT1 inhibits proliferation and migration of mesothelioma cells by targeting FOXM1, ONCOLOGY REPORTS, 47(2), 202202
    Link to Paper Search Results by DOI
  5. Glypican-1 is a novel immunohistochemical marker to differentiate poorly differentiated squamous cell carcinoma from solid predominant adenocarcinoma of the lung., Transl Lung Cancer Res, 10(2), 766-775, 202102
    Link to Paper Search Results by DOI
  6. SOX6 is a Novel Immunohistochemical Marker for Differential Diagnosis of Epithelioid Mesothelioma From Lung Adenocarcinoma, AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 44(9), 1259-1265, 202009
    Link to Paper Search Results by DOI
  7. Optic tract edema in craniopharyngioma as a predictor of BRAFV600E mutation presence, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 53(5), 378-385, 20230429
    Link to Paper Search Results by DOI
  8. Residual diffusion-weighted imaging hyperintense signal in primary central nervous system lymphoma can predict early recurrence, JOURNAL OF NEURO-ONCOLOGY, 165(1), 171-179, 202310
    Link to Paper Search Results by DOI
  9. Musashi-1 Is a Novel Immunohistochemical Marker of Neuroendocrine Carcinoma of the Lung, CANCERS, 15(23), 202312
    Link to Paper Search Results by DOI
  10. Long Non-coding RNA LINC00152 Requires EZH2 to Promote Mesothelioma Cell Proliferation, Migration, and Invasion, ANTICANCER RESEARCH, 43(12), 5367-5375, 202312
    Link to Paper Search Results by DOI
  11. Differences in invasiveness and recurrence rate among nonfunctioning pituitary neuroendocrine tumors depending on tumor subtype, NEUROSURGICAL REVIEW, 46(1), 20231130
    Link to Paper Search Results by DOI
  12. Characteristics and therapeutic strategies of brain and cranial radiation-induced sarcoma: analysis of 165 cases from our case experience and comprehensive review, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 53(10), 905-911, 20231004
    Link to Paper Search Results by DOI
  13. Usefulness of NF2 hemizygous loss detected by fluorescence in situ hybridization in diagnosing pleural mesothelioma in tissue and cytology material: A multi-institutional study, LUNG CANCER, 175, 27-35, 202301
    Link to Paper Search Results by DOI
  14. Usefulness of NF2 hemizygous loss detected by fluorescence in situ hybridization in diagnosing pleural mesothelioma in tissue and cytology material: A multi-institutional study, Lung Cancer, 175(1), 27-35, 2022
  15. Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma, BMC CANCER, 23(1), 20230314
    Link to Paper Search Results by DOI
  16. Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27(Kip1), FRONTIERS IN ONCOLOGY, 11, 20220119
    Link to Paper Search Results by DOI
  17. Serum S100 calcium-binding protein A4 as a novel predictive marker of acute exacerbation of interstitial pneumonia after surgery for lung cancer, BMC PULMONARY MEDICINE, 21(1), 20210602
    Link to Paper Search Results by DOI
  18. MUC4 immunohistochemistry is useful in distinguishing epithelioid mesothelioma from adenocarcinoma and squamous cell carcinoma of the lung, SCIENTIFIC REPORTS, 8, 20180109
    Link to Paper Search Results by DOI
  19. Therapeutic strategies and genetic profile comparisons in small cell carcinoma and large cell neuroendocrine carcinoma of the lung using next-generation sequencing, ONCOTARGET, 8(65), 108936-108945, 20171212
    Link to Paper Search Results by DOI
  20. Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1, MOLECULAR CELL, 64(1), 176-188, 20161006
    Link to Paper Search Results by DOI
  21. Multicentric Glioma Develops via a Mutant IDH1-Independent Pathway: Immunohistochemical Study of Multicentric Glioma., Pathobiology., 2016 Aug 24. [Epub ahead of print](2016 Aug 24. [Epub ahead of print]), 2016 Aug 24. [Epub ahead of print]-2016 Aug 24. [Epub ahead of print], 20160824
  22. CD26 Overexpression Is Associated with Prolonged Survival and Enhanced Chemosensitivity in Malignant Pleural Mesothelioma, CLINICAL CANCER RESEARCH, 18(5), 1447-1456, 20120301
    Link to Paper Search Results by DOI
  23. Myogenic antigen expression is useful for differentiation between epithelioid mesothelioma and non-neoplastic mesothelial cells., Histopathology, 56(7), 969-74, 20100601
  24. Evaluation of apoptosis and immunohistochemical expression of the apoptosis-related proteins in mesothelioma., Hiroshima Journal of Medical Sciences, 59(2), 27-33, 20100601
  25. A case of nodular female breast fasciitis, J. Jpn. Soc. Clin. Cytol., 48(4), 201-205, 20090722
  26. Letter to the Editor, PATHOLOGY INTERNATIONAL, 59(4), 274-274, 20090401
  27. Clinicopathological and immunohistochemical features of three pilomyxoid astrocytomas : Comparative study with 11 pilocytic astrocytomas, 59(2), 80-85, 20090201
  28. Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer, Cancer Sci, 99(8), 1570-1577, 20080810
  29. Differential diagnosis of sarcomatoid mesothelioma from true sarcoma and sarcomatoid carcinoma using immunohistochemistry, Pathol Int, 58(2), 75-83, 20080201
  30. Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer, Cancer Sci, 97(8), 737-745, 20060810
  31. Expression of vascular endothelial growth factor-C and its receptor in invasive micropapillary carcinoma of the breast, 56(5), 256-261, 20060501
  32. The Reversed Apical Pattern of MUC1 Expression Is Characteristics of Invasive Micropapillary Carcinoma of the Breast, Breast Cancer, 13(1), 58-63, 20060105
  33. A Case of Desmoplastic Malignant Pleural Mesothelioma Treated With Induction Chemotherapy and Subsequent Extrapleural Pneumonectomy, Japanese Journal of Lung Cancer, 45(7), 851-856, 20051220
  34. Increases of amphiregulin and transforming growth factor-alpha in serum as predictors of poor response to gefitinib among patients with advanced non-small cell lung cancers, CANCER RESEARCH, 65(20), 9176-9184, 20051015
    Link to Paper Search Results by DOI
  35. Loss of expression of E-cadherin and β-catenin is associated with progression of pulmonary adenocarcinoma, 55(1), 14-18, 20050101
  36. Esophageal carcinosarcoma with basaloid squamous carcinoma and rhabdomyosarcoma components with TP53 mutation, Pathol Int, 54(10), 803-809, 20041001
  37. Inactivation of the p16 gene by hypermethylation and loss of heterozygosity in adenocarcinoma of the lung, Pathol Int, 54(7), 486-489, 20040701
  38. Meningioma in mature cystic teratoma of the ovary, Pathol Int, 54(7), 543-548, 20040701
  39. Granulocyte-Macrophage Colony-Stimulating Factor and Granulocyte Colony-Stimulating Factor-Producing Malignant Pleural Mesothelioma Accompanied by Eosinophilic Pleural Fluid, Japanese Journal of Lung Cancer, 44(1), 25-30, 20040220
  40. Myxopapillary ependymoma with anaplastic features, 53(10), 700-703, 20031001
  41. Case of clear cell ependymoma of medulla oblongata : Clinicopathological and immunohistochemical study with literature review, Pathol Int, 53(5), 297-302, 20030501
  42. Co-existence of Carcinosarcoma and Adenoid Basal Carcinoma of the Uterine Cervix with Special Reference toits Correlation with Human Papilloma Virus Infection., Int. J Gynecol Pathol., 21(2), 186-190, 20020401
  43. Loss of heterozygosity and microsatellite instability in epithelial hyperplasia of the breast, Journal of Experimental Therapeutics and Oncology, 2(1), 9-18, 20020401
  44. Co-existent carcinosarcoma and adenoid basal carcinoma of the uterine cervix and correlation with human papilloma virus infection, International Journal of Gynecological Pathology, 21(2), 186-190, 20020401
  45. Co-existent carcinosarcoma and adenoid basal carcinoma of the uterine cervix and correlation with human papillomavirus infection., Int. J Gynecol Pathol., 21(2), 186-90, 20020401
  46. Heterogeneity of expression of cytokeratin subtypes in squamous cell carcinoma of the lung : With special reference to CK14 overexpression in cancer of high-proliferative and lymphogenous metastatic potential, 52(4), 286-293, 20020401
  47. Meningioangiomatosis Occurring in a Young Male without Neurofibromatosis -With Special Reference to its Histogenesis and LOH in the NF2 Gene Region-, Am. J. Surg. Pathol., 26(1), 125-126, 20020101
  48. Meningioangiomatosis occurring in a young male without neurofibromatosis: with special reference to its histogenesis and loss of heterozygosity in the NF2 gene region., Am. J. Surg. Pathol., 26(1), 125-129, 20020101
  49. Heterogeneous Genetic Alterations in Ovarian Mucinous Tumors-Application and Usefulness of Laser Capture Microdissection-, Human Pathology, 32(11), 1203-1208, 20011101
  50. An Extraabdominal Desmoid Tumor Presenting as an Intrathoracic Tumor (Intrathoracic Desmoid Tumor): A Case Report and Review of Literature., Pathol. Int., 824-828, 20011001
  51. Extra-abdominal desmoid tumor presenting as an intrathoracic tumor : Case report and literature review, Pathol Int, 51(10), 824-828, 20011001
  52. Loss of heterozygosity and microsatellite instability in epithelial hyperplasia of the breast, J. Exp. Ther. Oncol., 2(1), 1-10, 20010901
  53. PARAGANGLIOMA OF THE URINARY BLADDER : A CASE REPORT, 63(3), 151-153, 20010320
  54. In Vivo Histological Changes Occurring in Hydroxyapatite Cranial Reconstruction, 神経外科, 41(2), 100-104, 20010215
  55. Correlation between morphological heterogeneity and genetic alteration within one tumor in adenocarcinomas of the lung, Pathology International, 50(11), 891-896, 20001101
  56. Correlation between genetic alterations and histopathological subtypes in bronchiolo-alveolar carcinoma and atypical adenomatous hyperplasia of the lung, Pathology International, 50(10), 778-785, 20001001
  57. Genetic Alterations in Ovarian Mucinous Tumors -with Special Reference to the Histogenesis-, Acta Histochem Cytochem, 123-129, 20000201
  58. Idiopathic granulomatous meningoencephalitis presenting as an intracranial tumor., Pathol. Int., 49(12), 1084-1088, 19991201
  59. Idiopathic granulomatous meningoencephalitis presenting as an intracranial tumor, Pathology International, 49(12), 1084-1088, 19991201
  60. Correlation Among Histological Subtypes, Clinicopathological Factors, Expression of p53 Protein and Proliferative Activity in Adenocarcinoma of the Lung, Japanese Journal of Lung Cancer, 39(7), 995-1000, 19991201
  61. Down-regulation of KAI1 Messenger RNA Expression Is Not Associated with Loss of Heterozygosity of the KAI1 Gene Region in Lung Adenocarcinoma, Jpn J Cancer Res, 90(9), 970-976, 19990930
  62. p21WAF1/CIP1 Expression in Primary Lung Adenocarcinomas: Heterogeneous Expression in Tumor Tissues and Correlation with p53 Expression and Proliferative Activities., Carcinogenesis, 19(10), 1755-1761, 19981001
  63. Angiomyofibroblastoma of the vulva : A mitotically active variant?, Pathology International, 48, 292-296, 19980401
  64. Tubular Seminoma of the testis : Report of a Case, Patholgy International, 49, 676-679, 19980401
  65. Solitary fibrous tumor of the prostate, Pathology International, 47, 713-717, 19970401
  66. p16/CDKN2 gene and p53 gene alterations in Japanese non-smoking female lung adenocarcinoma, Jpn.J.Cancer Res., 87, 134-140, 19960401
  67. p16/CDKN2 Gene and p53 Geno Alteration in Japanese Non-smoking Female Lung Adenocarcinoma, Jpn J Cancer Res, 87(2), 134-140, 19960229
  68. p16/CDKN2 Gene and p53 Gene Alterations in Japanese Non-smoking Female Lung Adenocarcioma., Jpn.J.Cancer Res., 134-140, 19960201
  69. Primary Carcinoid Tumor of the Kidney with Special Reference to its Histogenesis., Pathol. Int., 894-900, 19960101
  70. Effects of K-ras Gene Mutations in the Development of Lung Lesions Induced by 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone in A/J Mice, Jpn J Cancer Res, 87(1), 44-50, 19960101
  71. PATHOLOGY OF RESPIRATORY TRACT IN FORMER WORKERS IN MUSTARD GAS FACTORY : A REVIEW, J Toxicol Pathol, 8(4), 343-353, 19951201
  72. An Autopsy Case of Malignant Pleural Mesothelioma with Prominent Deposition of Chrysotile in the Lung, Japanese Journal of Lung Cancer, 35(6), 783-788, 19951020
  73. Pathological Findings of Atypical Carcinoid Tumors of the Thymus, Japanese Journal of Lung Cancer, 34(7), 1093-1098, 19941220
  74. p53 Protein Accumulates Frequently in Early Bronchial Neoplasia., Cancer Res., 1-6, 19930701
  75. Ovarian Sex Cord Tumor with Annular Tubules - A Case Report and Review of the Literature in Japanese., Hiroshima J. Med. Sci., 37-42, 19920201
  76. Quantitative risk assessment of carcinogenicity of urethane (ethyl carbamate) on the basis of long-term oral administration to B6C3F1 mice, 380-385, 19910401
  77. Usefulness of serum S100A4 and positron-emission tomography on lung cancer accompanied by interstitial pneumonia, THORACIC CANCER, 14(4), 381-388, 202302
    Link to Paper Search Results by DOI
  78. Challenges and limitation of MTAP immunohistochemistry in diagnosing desmoplastic mesothelioma/sarcomatoid pleural mesothelioma with desmoplastic features, ANNALS OF DIAGNOSTIC PATHOLOGY, 60, 202210
    Link to Paper Search Results by DOI
  79. Characteristics and therapeutic strategies of radiation-induced glioma: case series and comprehensive literature review, JOURNAL OF NEURO-ONCOLOGY, 159(3), 531-538, 202209
    Link to Paper Search Results by DOI
  80. Downregulation of FTL decreases proliferation of malignant mesothelioma cells by inducing G(1) cell cycle arrest, ONCOLOGY LETTERS, 23(6), 202206
    Link to Paper Search Results by DOI
  81. Sensitivity and optimal clinicopathological features for mutation-targeted liquid biopsy in pN0M0 EGFR-mutant lung adenocarcinoma, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 148(6), 1419-1428, 202206
    Link to Paper Search Results by DOI
  82. Identification of Novel Diagnostic Markers for Malignant Pleural Mesothelioma Using a Reverse Translational Approach Based on a Rare Synchronous Tumor, DIAGNOSTICS, 12(2), 202202
    Link to Paper Search Results by DOI
  83. Intratumoral Hemorrhage After Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus Caused by Brain Tumors, WORLD NEUROSURGERY, 158, E256-E264, 202202
    Link to Paper Search Results by DOI
  84. Diffusion-weighted imaging-gadolinium enhancement mismatch sign in diffuse midline glioma, EUROPEAN JOURNAL OF RADIOLOGY, 147, 202202
    Link to Paper Search Results by DOI
  85. Clinical Behavior of Combined Versus Pure High-Grade Neuroendocrine Carcinoma, CLINICAL LUNG CANCER, 23(1), E9-+, 202201
    Link to Paper Search Results by DOI
  86. Comprehensive analysis of the clinicopathological features, targetable profile, and prognosis of mucinous adenocarcinoma of the lung, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 147(12), 3709-3718, 202112
    Link to Paper Search Results by DOI
  87. Pathological high malignant grade is higher risk of recurrence in pN0M0 invasive lung adenocarcinoma, even with small invasive size, THORACIC CANCER, 12(23), 3141-3149, 202112
    Link to Paper Search Results by DOI
  88. Tumor contact length of prostate cancer determined by a three-dimensional method on multiparametric magnetic resonance imaging predicts extraprostatic extension and biochemical recurrence, INTERNATIONAL JOURNAL OF UROLOGY, 28(10), 1012-1018, 202110
    Link to Paper Search Results by DOI
  89. TUBB3 is associated with PTEN, neuroendocrine differentiation, and castration resistance in prostate cancer, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 39(6), 202106
    Link to Paper Search Results by DOI
  90. Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor, EUROPEAN JOURNAL OF RADIOLOGY, 136, 202103
    Link to Paper Search Results by DOI
  91. Bronchial mucosal ablation for bronchial stump closure in right pneumonectomy: a case report., J Med Case Rep, 15(1), 71-71, 202102
    Link to Paper Search Results by DOI
  92. Clinicopathological significance of intelectin-1 in colorectal cancer: Intelectin-1 participates in tumor suppression and favorable progress, PATHOLOGY INTERNATIONAL, 70(12), 943-952, 202012
    Link to Paper Search Results by DOI
  93. Radiological and Immunostaining Characteristics of H3.3 G34R-Mutant Glioma: A Report of 3 Cases and Review of the Literature, PEDIATRIC NEUROSURGERY, 55(5), 319-325, 202012
    Link to Paper Search Results by DOI
  94. Clinicopathological significance of intelectin-1 in colorectal cancer: Intelectin-1 participates in tumor suppression and favorable progress., Pathol Int, 70(12), 943-952, 202012
    Link to Paper Search Results by DOI
  95. Microtubule-associated protein tau (MAPT) promotes bicalutamide resistance and is associated with survival in prostate cancer, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 38(10), 202010
    Link to Paper Search Results by DOI
  96. Microtubule-Associated Protein Tau (Mapt) Promotes Bicalutamide Resistance and Is Associated with Survival in Prostate Cancer., Urol Oncol, 38(10), 319-325, 202010
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  97. ★, SOX6 Is a Novel Immunohistochemical Marker for Differential Diagnosis of Epithelioid Mesothelioma From Lung Adenocarcinoma., Am J Surg Pathol, 44(9), 1259-1265, 202009
    Link to Paper Search Results by DOI
  98. Radiology Profile as a Potential Instrument to Differentiate Between Posterior Fossa Ependymoma (PF-EPN) Group A and B, WORLD NEUROSURGERY, 140, E320-E327, 202008
    Link to Paper Search Results by DOI
  99. Radiology Profile as a Potential Instrument to Differentiate between Posterior Fossa Ependymoma (Pf-Epn) Group a and B., World Neurosurg, 140(8), e320-e327, 202008
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  100. A Case of Peritoneal Dissemination and Splenic Metastasis after Gastric Cancer Surgery That Could Be Controlled with Multidisciplinary Treatment., Case Rep Oncol, 13(3), 1164-1170, 202008
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  101. Advantage of high b value diffusion -weighted imaging for differentiation of common pediatric brain tumors in posterior fossa, EUROPEAN JOURNAL OF RADIOLOGY, 128, 202007
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  102. LPrognostic Impact of Programmed Death-ligand 1 and Surrounding Immune Status on Stage I Lung Cancer, CLINICAL LUNG CANCER, 21(4), E302-E314, 202007
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  103. Prognostic Impact of Programmed Death-Ligand 1 and Surrounding Immune Status on Stage I Lung Cancer., Clin Lung Cancer, 21(4), e302-e314, 202007
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  104. Investigation of surgical technique for bronchial stump closure after lobectomy in animal model, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 68(6), 609-614, 202006
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  105. Inhibition of miR-18a-3p reduces proliferation of mesothelioma cells and sensitizes them to cisplatin, ONCOLOGY LETTERS, 19(6), 4161-4168, 202006
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  106. Inhibition of Mir-18a-3p Reduces Proliferation of Mesothelioma Cells and Sensitizes Them to Cisplatin., Oncol Lett, 19(6), 4161-4168, 202006
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  107. T2-FLAIR mismatch sign in dysembryoplasticneuroepithelial tumor, EUROPEAN JOURNAL OF RADIOLOGY, 126, 202005
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  108. Radiological and Immunostaining Characteristics of H3.3 G34R-Mutant Glioma: A Report of 3 Cases and Review of the Literature., Pediatr Neurosurg, 55(5), 319-325, 202005
    Link to Paper Search Results by DOI
  109. Intense Expression of EGFR L858R Characterizes the Micropapillary Component and L858R Is Associated with the Risk of Recurrence in pN0M0 Lung Adenocarcinoma with the Micropapillary Component, ANNALS OF SURGICAL ONCOLOGY, 27(3), 945-955, 202003
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  110. Intense Expression of Egfr L858r Characterizes the Micropapillary Component and L858r Is Associated with the Risk of Recurrence in Pn0m0 Lung Adenocarcinoma with the Micropapillary Component., Ann Surg Oncol, 27(3), 945-955, 202003
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  111. Magnetic resonance imaging/transrectal ultrasonography fusion targeted prostate biopsy finds more significant prostate cancer in biopsy-naive Japanese men compared with the standard biopsy, INTERNATIONAL JOURNAL OF UROLOGY, 27(2), 140-146, 202002
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  112. Utility of dual-energy CT for predicting the vascularity of meningiomas, EUROPEAN JOURNAL OF RADIOLOGY, 123, 202002
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  113. Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature, WORLD NEUROSURGERY, 134, E360-E371, 202002
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  114. Magnetic Resonance Imaging/Transrectal Ultrasonography Fusion Targeted Prostate Biopsy Finds More Significant Prostate Cancer in Biopsy-Naive Japanese Men Compared with the Standard Biopsy., Int J Urol., 27(2), 140-146, 202002
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  115. A Rare Case of Gastric Schwannoma: A Case Report and Literature Review, Case Rep Oncol., 13(1), 330-335, 202001
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  116. Retrospective immunohistological study of autopsied lungs in patients with acute exacerbation of interstitial pneumonia managed with extracorporeal membrane oxygenation, JOURNAL OF THORACIC DISEASE, 11(11), 4436-4443, 201911
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  117. Effect of bevacizumab against cystic components of brain tumors, CANCER MEDICINE, 8(15), 6519-6527, 201911
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  118. Synchronicity of genetic variants between primary sites and metastatic lymph nodes, and prognostic impact in nodal metastatic lung adenocarcinoma, JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 145(9), 2325-2333, 201909
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  119. Characteristics of 5015 Salivary Gland Neoplasms Registered in the Hiroshima Tumor Tissue Registry over a Period of 39 Years, JOURNAL OF CLINICAL MEDICINE, 8(5), 201905
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  120. Mucin 21 is a novel, negative immunohistochemical marker for epithelioid mesothelioma for its differentiation from lung adenocarcinoma, HISTOPATHOLOGY, 74(4), 545-554, 201903
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  121. Increased risk of recurrence in resected EGFR-positive pN0M0 invasive lung adenocarcinoma, THORACIC CANCER, 9(12), 1594-1602, 201812
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  122. Perfusion Computed Tomography Parameters Are Useful for Differentiating Glioblastoma, Lymphoma, and Metastasis, WORLD NEUROSURGERY, 119, E890-E897, 201811
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  123. Improved differentiation between high- and low-grade gliomas by combining dual-energy CT analysis and perfusion CT, MEDICINE, 97(32), 201808
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  124. Glypican-1 immunohistochemistry is a novel marker to differentiate epithelioid mesothelioma from lung adenocarcinoma, MODERN PATHOLOGY, 31(5), 809-815, 201805
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  125. Proton Magnetic Resonance Spectroscopy Detection of High Lipid Levels and Low Apparent Diffusion Coefficient Is Characteristic of Germinomas, WORLD NEUROSURGERY, 112, E84-E94, 201804
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  126. RELA fusion-positive anaplastic ependymoma: molecular characterization and advanced MR imaging., Brain Tumor Pathol., 35(1), 41-45, 201801
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  127. PIM1 knockdown inhibits cell proliferation and invasion of mesothelioma cells, INTERNATIONAL JOURNAL OF ONCOLOGY, 50(3), 1029-1034, 201703
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  128. Utility and pitfalls of immunohistochemistry in the differential diagnosis between epithelioid mesothelioma and poorly differentiated lung squamous cell carcinoma, HISTOPATHOLOGY, 70(3), 375-384, 201702
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  129. Prognostic significance of vascular invasion in intermediate-grade subtype of lung adenocarcinoma, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 46(11), 1015-1021, 201611
    Link to Paper Search Results by DOI
  130. Prognostic Role of Subtype Classification in Small-Sized Pathologic N0 Invasive Lung Adenocarcinoma, ANNALS OF THORACIC SURGERY, 102(5), 1668-1673, 201611
    Link to Paper Search Results by DOI
  131. Pleural irregularities and mediastinal pleural involvement in early stages of malignant pleural mesothelioma and benign asbestos pleural effusion, EUROPEAN JOURNAL OF RADIOLOGY, 85(9), 1594-1600, 201609
    Link to Paper Search Results by DOI
  132. Fatal pleural mesothelioma in Japan (2003-2008): evaluation of computed tomography findings, JAPANESE JOURNAL OF RADIOLOGY, 34(6), 432-438, 201606
    Link to Paper Search Results by DOI
  133. Computed Tomographic Features of Malignant Peritoneal Mesothelioma, ANTICANCER RESEARCH, 36(3), 1067-1072, 201603
  134. Magnetic resonance spectroscopy detection of high lipid levels in intraaxial tumors without central necrosis: a characteristic of malignant lymphoma, JOURNAL OF NEUROSURGERY, 122(6), 1370-1379, 201506
    Link to Paper Search Results by DOI
  135. Prognostic impact of lymphatic invasion for pathological stage I squamous cell carcinoma of the lung, GENERAL THORACIC AND CARDIOVASCULAR SURGERY, 63(3), 153-158, 201503
    Link to Paper Search Results by DOI
  136. Propensity score-matched analysis of adjuvant chemotherapy for stage I non-small cell lung cancer, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 148(4), 1179-1185, 201410
    Link to Paper Search Results by DOI
  137. Prediction for prognosis of resected pT1a-lbN0M0 adenocarcinoma based on tumor size and histological status: Relationship of TNM and IASLC/ATS/ERS classifications, LUNG CANCER, 85(2), 270-275, 201408
    Link to Paper Search Results by DOI
  138. Role of lymphatic invasion in the prognosis of patients with clinical node-negative and pathologic node-positive lung adenocarcinoma., J Thorac Cardiovasc Surg, 147(6), 1820-1826, 201406
  139. The prognostic role of pathologic invasive component size, excluding lepidic growth, in stage I lung adenocarcinoma, JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 146(3), 580-585, 201309
    Link to Paper Search Results by DOI
  140. Treatment and survival analyses of malignant mesothelioma in Japan, ACTA ONCOLOGICA, 52(4), 803-808, 201305
    Link to Paper Search Results by DOI
  141. CD9 expression as a favorable prognostic marker for patients with malignant mesothelioma, ONCOLOGY REPORTS, 29(1), 21-28, 201301
    Link to Paper Search Results by DOI
  142. Role of perfusion-weighted imaging at 3 T in the histopathological differentiation between astrocytic and oligodendroglial tumors, EUROPEAN JOURNAL OF RADIOLOGY, 81(8), 1863-1869, 201208
    Link to Paper Search Results by DOI
  143. National survey of malignant mesothelioma and asbestos exposure in Japan, CANCER SCIENCE, 103(3), 483-490, 201203
    Link to Paper Search Results by DOI
  144. Lymphomas and glioblastomas: Differences in the apparent diffusion coefficient evaluated with high b-value diffusion-weighted magnetic resonance imaging at 3 T, EUROPEAN JOURNAL OF RADIOLOGY, 81(2), 339-344, 201202
    Link to Paper Search Results by DOI
  145. Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas, EUROPEAN JOURNAL OF RADIOLOGY, 80(2), 412-417, 201111
    Link to Paper Search Results by DOI
  146. Clinical Study on Mesothelioma in Japan: Relevance to Occupational Asbestos Exposure, AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, 53(11), 1081-1087, 201011
    Link to Paper Search Results by DOI
  147. Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesothelioma, ONCOLOGY REPORTS, 24(2), 423-431, 201008
    Link to Paper Search Results by DOI
  148. TRIGEMINAL NEUROPATHY FROM PERINEURAL SPREAD OF AN AMYLOIDOMA DETECTED BY BLINK REFLEX AND THIN-SLICE MAGNETIC RESONANCE IMAGING, MUSCLE & NERVE, 41(6), 875-878, 201006
    Link to Paper Search Results by DOI
  149. Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions, EUROPEAN JOURNAL OF RADIOLOGY, 74(3), 420-427, 201006
    Link to Paper Search Results by DOI
  150. Evaluation of Apoptosis and Immunohistochemical Expression of the Apoptosis-related Proteins in Mesothelioma, Hiroshima Journal of Medical Sciences, 59(2), 27-33, 201006
  151. Glioblastoma treated with postoperative radio-chemotherapy: Prognostic value of apparent diffusion coefficient at MR imaging, EUROPEAN JOURNAL OF RADIOLOGY, 73(3), 532-537, 201003
    Link to Paper Search Results by DOI
  152. Accuracy of pathological diagnosis of mesothelioma cases in Japan: Clinicopathological analysis of 382 cases, LUNG CANCER, 66(2), 191-197, 200911
    Link to Paper Search Results by DOI
  153. Caveolin-1 is a novel immunohistochemical marker to differentiate epithelioid mesothelioma from lung adenocarcinoma, HISTOPATHOLOGY, 55(1), 10-19, 200907
    Link to Paper Search Results by DOI
  154. ★, Value of immunohistochemistry in the differential diagnosis of pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma, HISTOPATHOLOGY, 54(6), 667-676, 200905
    Link to Paper Search Results by DOI
  155. Clinicopathological and immunohistochemical features of three pilomyxoid astrocytomas: Comparative study with 11 pilocytic astrocytomas, PATHOLOGY INTERNATIONAL, 59(2), 80-85, 200902
    Link to Paper Search Results by DOI
  156. Asbestos and lung cancer, 57(9), 2274-2277, 200809
  157. Differential diagnosis of sarcomatoid mesothelioma from true sarcoma and sarcomatoid carcinoma using immunohistochemistry, PATHOLOGY INTERNATIONAL, 58(2), 75-83, 200802
    Link to Paper Search Results by DOI
  158. Immunohistochemical marker panels for distinguishing between epithelioid mesothelioma and lung adenocarcinoma, PATHOLOGY INTERNATIONAL, 57(4), 190-199, 200704
    Link to Paper Search Results by DOI
  159. Characterization of SEZ6L2 cell-surface protein as a novel prognostic marker for lung cancer, CANCER SCIENCE, 97(8), 737-745, 200608
    Link to Paper Search Results by DOI
  160. Expression of vascular endothelial growth factor-C and its receptor in invasive micropapillary carcinoma of the breast, PATHOLOGY INTERNATIONAL, 56(5), 256-261, 200605
    Link to Paper Search Results by DOI
  161. Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung, JOURNAL OF CLINICAL PATHOLOGY, 58(10), 1076-1080, 200510
    Link to Paper Search Results by DOI
  162. Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma, JOURNAL OF PATHOLOGY, 207(2), 185-198, 200510
    Link to Paper Search Results by DOI
  163. Aberrant methylation and loss of expression of O-6-methylguanine-DNA methyltransferase in pulmonary squamous cell carcinoma and adenocarcinoma, PATHOLOGY INTERNATIONAL, 55(6), 303-309, 200506
    Link to Paper Search Results by DOI
  164. Loss of expression of E-cadherin and beta-catenin is associated with progression of pulmonary adenocarcinoma, PATHOLOGY INTERNATIONAL, 55(1), 14-18, 200501
    Link to Paper Search Results by DOI
  165. Esophageal carcinosarcoma with basaloid squamous carcinoma and rhabdomyosarcoma components with TP53 mutation, PATHOLOGY INTERNATIONAL, 54(10), 803-809, 200410
    Link to Paper Search Results by DOI
  166. Aberrant methylation of p14(ARF), p15(INK4b) and p16(INK4a) genes and location of the primary site in pulmonary squamous cell carcinoma, PATHOLOGY INTERNATIONAL, 54(8), 549-555, 200408
    Link to Paper Search Results by DOI
  167. Inactivation of the p16 gene by hypermethylation and loss of heterozygosity in adenocarcinoma of the lung, PATHOLOGY INTERNATIONAL, 54(7), 486-489, 200407
    Link to Paper Search Results by DOI
  168. Meningioma in mature cystic teratoma of the ovary, PATHOLOGY INTERNATIONAL, 54(7), 543-548, 200407
    Link to Paper Search Results by DOI
  169. Methylation of p14(ARF) gene in meningiomas and its correlation to the p53 expression and mutation, MODERN PATHOLOGY, 17(6), 705-710, 200406
    Link to Paper Search Results by DOI
  170. Expression of MUC1, MUC2, MUC5AC, and MUC6 in atypical adenomatous hyperplasia, bronchioloalveolar carcinoma, adenocarcinoma with mixed subtypes, and mucinous bronchioloalveolar carcinoma of the lung, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 121(5), 644-653, 200405
    Link to Paper Search Results by DOI
  171. Myxopapillary ependymoma with anaplastic features, PATHOLOGY INTERNATIONAL, 53(10), 700-703, 200310
    Link to Paper Search Results by DOI
  172. Heterogeneity of expression of cytokeratin subtypes in squamous cell carcinoma of the lung: With special reference to CK14 overexpression in cancer of high-proliferative and lymphogenous metastatic potential, PATHOLOGY INTERNATIONAL, 52(4), 286-293, 200204
    Link to Paper Search Results by DOI
  173. Meningioangiomatosis occurring in a young male without neurofibromatosis - With special reference to its histogenesis and loss of heterozygosity in the NF2 gene region, AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 26(1), 125-129, 200201
    Link to Paper Search Results by DOI
  174. In vivo histological changes occurring in hydroxyapatite cranial reconstruction - Case report, NEUROLOGIA MEDICO-CHIRURGICA, 41(2), 100-104, 200102
    Link to Paper Search Results by DOI
  175. 'Adenomyomatous' hamartoma of the lung, PATHOLOGY INTERNATIONAL, 50(12), 984-986, 200012
    Link to Paper Search Results by DOI
  176. Correlation between morphological heterogeneity and genetic alteration within one tumor in adenocarcinomas of the lung, PATHOLOGY INTERNATIONAL, 50(11), 891-896, 200011
    Link to Paper Search Results by DOI
  177. Correlation between genetic alterations and histopathological subtypes in bronchiolo-alveolar carcinoma and atypical adenomatous hyperplasia of the lung, PATHOLOGY INTERNATIONAL, 50(10), 778-785, 200010
    Link to Paper Search Results by DOI
  178. Tubular seminoma of the testis, Pathology International, 49(7), 676-679, 199907
  179. Angiomyofibroblastoma of the vulva : A mitotically active variant?, Pathology International, 48(4), 292-296, 199804
  180. Solitary fibrous tumor of the prostate, Pathology International, 47(10), 713-717, 199710
  181. Primary carcinoid tumor of the kidney with special reference to its histogenesis, Pathology International, 46(11), 894-900, 199611
  182. Alteration of the p53 gene of lung carcinomas with sarcomatous transformation (spindle cell carcinoma) : Analysis of four cases, Pathol Int., 46(1), 38-45, 199601
  183. ★, p53 mutations in lung cancers from Japanese mustard gas workers., Carcinogenesis, 15(10):2075-9.(10), 2075-2079, 199412
  184. ★, p53 mutations in lung cancers from non-smoking atomic-bomb survivors., 342, 1520-1521, 199312
  185. ★, Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27/KIP1, Front Oncol, 2022
  186. Diffusion-weighted imaging-gadolinium enhancement mismatch sign in diffuse midline glioma., Eur J Radiol, 147, 110103, 2022
  187. Histopathological Analysis of False-positive Lesions in mpMRI/TRUS Fusion Prostate Biopsy, IN VIVO, 36(1), 496-500, 2022
    Link to Paper Search Results by DOI
  188. Metachronous Double Pituitary Adenoma with Altered Transcriptional Factor Profile: A Case Report and Literature Review., NMC Case Rep J, 4(6), 397-402, 2021
  189. The secondary tumor of the prostate derived from upper tract urothelial carcinoma: An autopsy case., IJU Case Rep, 4(6), 397-402, 2021
  190. Utility of Newly Proposed Grading System From International Association for the Study of Lung Cancer for Invasive Lung Adenocarcinoma., JTO Clin Res Rep, 2(2), 100126, 2021
  191. Sensitivity and optimal clinicopathological features for mutation-targeted liquid biopsy in pN0M0 EGFR-mutant lung adenocarcinoma., J Cancer Res Clin Oncol, 2021
  192. Intratumoral Hemorrhage After Endoscopic Third Ventriculostomy for Obstructive Hydrocephalus Caused by Brain Tumors., World Neurosurg, 2021
  193. Primary Small Intestinal Sarcomatoid Carcinoma: Report of a Rare Case and Literature Review, CASE REPORTS IN ONCOLOGY, 14(1), 538-544, 2021
    Link to Paper Search Results by DOI
  194. A Rare Case of Gastric Schwannoma: A Case Report and Literature Review, CASE REPORTS IN ONCOLOGY, 13(1), 330-335, 2020
    Link to Paper Search Results by DOI
  195. Drug-Induced Interstitial Pneumonia due to Application of FOLFOX as Adjuvant Chemotherapy after Rectal Cancer Surgery: A Case Report and Literature Review, CASE REPORTS IN ONCOLOGY, 13(2), 768-773, 2020
    Link to Paper Search Results by DOI
  196. A Case of Peritoneal Dissemination and Splenic Metastasis after Gastric Cancer Surgery That Could Be Controlled with Multidisciplinary Treatment, CASE REPORTS IN ONCOLOGY, 13(3), 1164-1170, 2020
    Link to Paper Search Results by DOI
  197. Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature., World Neurosurg., 134, e360-e371, 2020
    Link to Paper Search Results by DOI
  198. Utility of Dual-Energy Ct for Predicting the Vascularity of Meningiomas., Eur J Radiol., 123, 2020
    Link to Paper Search Results by DOI
  199. T2-Flair Mismatch Sign in Dysembryoplasticneuroepithelial Tumor., Eur J Radiol, 126, 2020
    Link to Paper Search Results by DOI
  200. Advantage of High B Value Diffusion-Weighted Imaging for Differentiation of Common Pediatric Brain Tumors in Posterior Fossa., Eur J Radiol, 2020
    Link to Paper Search Results by DOI
  201. Segmentectomy vs. lobectomy for clinical stage IA lung adenocarcinoma with spread through air spaces., Ann Thorac Surg, 2020
    Link to Paper Search Results by DOI
  202. Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the "Target Sign", INTERNAL MEDICINE, 58(8), 1157-1162, 2019
    Link to Paper Search Results by DOI
  203. Complete Response to Chemotherapy against the Recurrence of Neuroendocrine Carcinoma of the Breast in the Anterior Mediastinal Lymph Nodes of a Patient on Hemodialysis: A Case Report, CASE REPORTS IN ONCOLOGY, 12(1), 205-210, 2019
    Link to Paper Search Results by DOI
  204. Immunostaining of Increased Expression of Enhancer of Zeste Homolog 2 (EZH2) in Diffuse Midline Glioma H3K27M-Mutant Patients with Poor Survival, PATHOBIOLOGY, 86(2), 152-161, 2019
    Link to Paper Search Results by DOI
  205. Rare Cases of Low-Grade Appendiceal Mucinous Neoplasm: Two Case Reports and a Literature Review, CASE REPORTS IN ONCOLOGY, 12(2), 488-493, 2019
    Link to Paper Search Results by DOI
  206. Effect of bevacizumab against cystic components of brain tumors, Cancer Medicine, 8(15), 6519-6527, 2019
  207. Role for loss of nuclear PTEN in a harbinger of brain metastases., 2018
    Link to Paper Search Results by DOI
  208. The differences in histological changes among pulmonary vessels divided with an energy device., Interact Cardiovasc Thorac Surg., 2018
  209. Coexistence of gastrointestinal stromal tumor and leiomyosarcoma of the stomach presenting as a collision tumor: A case report and review of literature, Pathology International, 68, 313-317, 2018
  210. Improved differentiation between high- and low-grade gliomas by combining dual-energy CT analysis and perfusion CT., Medicine (Baltimore), 97(32), E11670, 2018
  211. Characteristics of Benign and Malignant Bone Tumors Registered in the Hiroshima Tumor Tissue Registry, 1973-2012., JB JS Open Access., 29(3), e0064, 2018
  212. Increased risk of recurrence in resected EGFR-positive pN0M0 invasive lung adenocarcinoma., Thorac Cancer., 2018
  213. ★, MUC21 is a novel, negative immunohistochemical marker for epithelioid mesothelioma for its differentiation from lung adenocarcinoma., Histopathology, 2018
  214. ★, miR-182 and miR-183 Promote Cell Proliferation and Invasion by Targeting FOXO1 in Mesothelioma, Front. Oncol., 2018
  215. Prognostic Role of Subtype Classification in Small-Sized Pathologic N0 Invasive Lung Adenocarcinoma., Ann Thorac Surg., 102(5), 1668-1673., 2017
  216. ★, MUC4, a novel immunohistochemical marker identified by gene expression profiling, differentiates pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma., Mod Pathol, 30([Epub ahead of print]), [Epub ahead of print]-[Epub ahead of print], 2017
  217. Multicentric Glioma Develops via a Mutant IDH1-Independent Pathway: Immunohistochemical Study of Multicentric Glioma, PATHOBIOLOGY, 84(2), 99-107, 2017
    Link to Paper Search Results by DOI
  218. ★, Identification of DAB2 and Intelectin-1 as Novel Positive Immunohistochemical Markers of Epithelioid Mesothelioma by Transcriptome Microarray Analysis for its Differentiation From Pulmonary Adenocarcinoma., Am J Surg Pathol., 2017
  219. Prognostic implications of the subcellular localization of survivin in glioblastomas treated with radiotherapy plus concomitant and adjuvant temozolomide., J Neurosurg., 2017(21), 2017
  220. Sellar Atypical Teratoid/Rhabdoid Tumor (AT/RT): A Clinicopathologically and Genetically Distinct Variant of AT/RT, Am J Surg Pathol, 41(7), 932-940, 2017
  221. Role for loss of nuclear PTEN in a harbinger of brain metastases, Journal of Clinical Neuroscience, 2017
  222. A comparison of clinicopathological features and prognosis in prostate cancer between atomic bomb survivors and control patients., Oncol Lett., 14(1), 299-305, 2017
    Link to Paper Search Results by DOI
  223. Inflammatory myofibroblastic tumors of the lung carrying a chimeric A2M-ALK gene: report of two infantile cases and review of the differential diagnosis of infantile pulmonary lesions., Hum Pathol., 2017, 2017
    Link to Paper Search Results by DOI
  224. Nonenhancing peritumoral hyperintense lesion on diffusion-weighted imaging in glioblastoma: a novel diagnostic and specific prognostic indicator., J Neurosurg, 2017
  225. ★, Use of Anti-Noxa Antibody for Differential Diagnosis between Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia., Pathobiology, 83((1):), 33-40, 2016
  226. ★, Differential microRNA expression profiling of mesothelioma and expression analysis of miR-1 and miR-214 in mesothelioma, International Journal of Oncology, 48(4), 1599-1607, 2016
  227. Benign fibrous histiocytoma arising at the temporal bone of an infant-case report and review of the literature., Childs Nerv Syst, [Epub ahead of print]([Epub ahead of print]), 2015
  228. CD26 overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma., Clin Cancer Res, 18(5), 1447-1456, 2012
  229. Clinical, Radiological, and Pathological Investigation of Asbestosis, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 8(3), 899-912, 2011
    Link to Paper Search Results by DOI
  230. Overexpression of CD26/DPPIV in mesothelioma tissue and mesothelioma cell lines, ONCOLOGY REPORTS, 26(6), 1369-1375, 2011
  231. Clinical Study on Mesothelioma in Japan: Relevance to Occupational Asbestos Exposure, AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, 53(11), 1081-1087, 2010
  232. WIF1 expression is down-regulated by its promoter methylation in mesothelioma, JOURNAL OF THORACIC ONCOLOGY, 4(9), S767-S767, 2009
  233. Familial occurrence of dysembryoplastic neuroepithelial tumor-like neoplasm of the septum pellucidum: Case report, NEUROSURGERY, 63(2), 370-372, 2008
    Link to Paper Search Results by DOI
  234. A Useful Antibody Panel for Differential Diagnosis Between Peritoneal Mesothelioma and Ovarian Serous Carcinoma in Japanese Cases, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 130(5), 771-779, 2008
  235. Immunohistochemical marker panels for distinguishing between epithelioid mesothelioma and lung adenocarcinoma, PATHOLOGY INTERNATIONAL, 57(4), 190-199, 2007
  236. A case of micronodular pneumocyte hyperplasia diagnosed through lung biopsy using thoracoscopy, RESPIRATION, 69(3), 277-279, 2002
    Link to Paper Search Results by DOI
  237. Extra-abdominal desmoid tumor presenting as an intrathoracic tumor: Case report and literature review, PATHOLOGY INTERNATIONAL, 51(10), 824-828, 2001
    Link to Paper Search Results by DOI
  238. Genetic alterations in ovarian mucinous tumors - With special reference to the histogenesis, ACTA HISTOCHEMICA ET CYTOCHEMICA, 33(2), 123-129, 2000
    Link to Paper Search Results by DOI
  239. A case of malignant pericardial mesothelioma with secondary pulmonary hypertension due to pulmonary vein occulusion:Comprehensive review of 56 cases reported in Japan, Shinzo, 32(5), 438-445, 2000
  240. Immunohistochemical and Molecular Pathological Analysis of Cell Cycle-related Factors in Human Multistep Carcinogenesis, Acta histochemica et cytochemica, 32(6), 1999
  241. Abstracts:THE 40TH MEMORIAL SCIENTIFIC MEETING OF THE JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY, Proceedings of the Japanese Histochemical Association, 32(6), 502-516, 1999
  242. Histopathological former workers engaged in mustard gas factory, Med J Hiroshima Univ, 38, 853-863, 1990
  243. Idipatic granulomatous meningoencepalitis presenting as an intracranial tumor, Pathology International, 49, 1084-1088
  244. Immunohistochemical study of Ki-67 (MIB-1), p53 protein, p21WAF1, p27KIP1expression in benign, atypical, and anplastic meningiomas, Human Pathology, 32, 970-975

Publications such as books

  1. 1991, Sporadic, Late-Onset Case of Familial Amyloid Polyneuropathy Type I (Andrade), A Clinical Study. , Kluwer Academic Publ., 1991, Joint work

Invited Lecture, Oral Presentation, Poster Presentation

  1. Pathological Diagnosis of Mesothelioma Using Immunohistochemistry, Yukio Takeshima, JICA project "The improvement of diagnostic ability in early phase of pneumoconiosis and asbestosis-exposure related respiratory disease", 2019/11/19, Without Invitation, English, other
  2. Pathological diagnosis of lung cancer, Yukio Takeshima, JICA project "The improvement of diagnostic ability in early phase of pneumoconiosis and asbestosis-exposure related respiratory disease", 2019/06/27, Without Invitation, English, other
  3. Practice and Utility of Immunohistochemistry and genetic analysis for Pathological Diagnosis, Yukio Takeshima, JICA project "The improvement of diagnostic ability in early phase of pneumoconiosis and asbestosis-exposure related respiratory disease", 2019/06/27, Without Invitation, English, Ulaanbaatar, Mongolia, other
  4. Diagnostic utility of MUC4 expression to differentiate epithelioid mesothelioma from lung adenocarcinoma and squamous cell carcinoma, Amatya V.J., Mawas A.S., Kushitani K., Kai Y., Miyata Y., Okada M. and Takeshima Y., IASLC 18th World Conference on Lung Cancer, 2017/10/15, Without Invitation, English, published
  5. Identification of DAB2 and Intelection-1 as novel positive immunohistochemical markers of epithelioid mesothelioma, Kushitani K., Amatya V.J., Okada Y., Katayama Y., Mawas A.S., Miyata Y., Okada M., Inai K., Kishimoto T. and Takeshima Y., IASLC 18th World Conference on Lung Cancer, 2017/10/15, Without Invitation, English, experimental
  6. Usefulness of immunohistochemistry in the differential diagnosis of epithelioid mesothelioma and lung squamous cell carcinoma, Kushitani K., Amatya V.J., Okada Y., Katayama Y., Mawas A.S., Miyata Y., Okada M., Inai K., Kishimoto T. and Takeshima Y., IASLC 18th World Conference on Lung Cancer, 2017/10/15, Without Invitation, English, published
  7. Therapeutic strategies and genetic comparisons in SCLC and LCNEC of the lung using next-generation sequencing, Ito M., Miyata Y., Hirano S., Kimura S., Irisuna F., Kushitani K., Tsutani Y., Takeshima Y. and Okada M., IASLC 18th World Conference on Lung Cancer, 2017/10/15, With Invitation, English, published

Social Activities

History as Peer Reviews of Academic Papers

  1. 2014, Pathology International, Editor, Editorial board
  2. 2015, Pathology International, Editor, Editorial board
  3. 2015, Hiroshima J Medical Sciences, Editor
  4. 2016, Pathobiology, Others, Reviewer, 2
  5. 2016, Cancer Science, Others, Reviewer, 1
  6. 2016, Pathology International, Editor
  7. 2016, Pathology International, Others, reviwer, 1
  8. 2016, Hiroshima J Medical Sciences, Editor
  9. 2017, Pathology International, Editor, Editor, 1