Hisato Kuniyoshi

Last Updated :2025/10/02

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
Web Site
http://home.hiroshima-u.ac.jp/hkuni/
E-mail
hkunihiroshima-u.ac.jp
Other Contact Details
Hiroshima University, 1-4-4 Kagamiyama, Higashi-hiroshima, 739-8528 Japan, Japan
TEL : (+81)82-424-7948 FAX : (+81)82-424-2459
Self-introduction
I am studying the molecular mechanisms of metamorphosis in jellyfish using techniques of organic chemistry and molecular biology.

Basic Information

Major Professional Backgrounds

  • 2002/04/01, 2006/10/31, Hiroshima University, Graduate School of Biosphere Science, Research Assistant
  • 2000/11/01, 2002/03/31, Hiroshima University, Department of Applied Biochemistry, Research Assistant
  • 1999/10/01, 2000/10/31, University of Toronto, Post-doctoral fellow
  • 1998/10/01, 1999/08/31, ERATO, Yamamoto Behavior Genes Project, Researcher
  • 1995/04/01, 1998/04/30, ERATO, Yamamoto Behavior Genes Project, Researcher
  • 1998/05/01, 1998/09/30, RIKEN, Brain Science Institute, Researcher
  • 2006/11/01, 2012/09/30, Hiroshima University, Graduate School of Biosphere Science, Lecturer
  • 1994/04/01, 1995/03/31, Japan Society for the Promotion, Research fellow
  • 2012/10/01, 2019/03/31, Hiroshima University, Graduate School of Biosphere Science, Associate Professor

Educational Backgrounds

  • The University of Tokyo, Graduate School, Division of Agricultural Science, Japan, 1991/04, 1994/03
  • The University of Tokyo, Faculty of Agriculture, Japan, 1985/04, 1989/03

Academic Degrees

  • Doctor of Agriculture, The University of Tokyo
  • Master of Agriculture, The University of Tokyo

Educational Activity

  • [Bachelor Degree Program] School of Applied Biological Science : Department of Applied Biological Science : Integrative Hydrospheric Science Program
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Food and AgriLife Science

In Charge of Primary Major Programs

  • Integrative Hydrospheric Science Program
  • Molecular Agro-Life Science Program

Research Fields

  • Agricultural sciences;Agricultural chemistry;Bioorganic chemistry

Research Keywords

  • jellyfish
  • metamorphosis
  • bioactive substance

Affiliated Academic Societies

  • Japan Society for Bioscience, Biotechnology, and Agrochemistry, 1989
  • The Japanese Peptide Society, 1990
  • The Molecular Biology Society of Japan, 1991
  • The Zoological Society of Japan, 2001
  • The Japanese Society of Fisheries Science, 2006

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Intensive, Laboratory Work in General Physics
  2. 2025, Undergraduate Education, 4Term, Introduction to Molecular Biochemistry
  3. 2025, Undergraduate Education, Intensive, Introduction to Molecular Biochemistry
  4. 2025, Undergraduate Education, 3Term, Research Front of Bioresource Science
  5. 2025, Undergraduate Education, Intensive, Laboratory Work in Hydrospheric BiologyII
  6. 2025, Undergraduate Education, 1Term, Exercises in Integrative Hydrospheric ScienceI
  7. 2025, Undergraduate Education, Second Semester, Graduation Thesis I
  8. 2025, Undergraduate Education, First Semester, Graduation Thesis II
  9. 2025, Undergraduate Education, Second Semester, Graduation Thesis III
  10. 2025, Undergraduate Education, 2Term, Hydrospheric Biochemistry
  11. 2025, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  12. 2025, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  13. 2025, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  14. 2025, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  15. 2025, Graduate Education (Master's Program) , Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  16. 2025, Graduate Education (Master's Program) , 2Term, Applied Molecular Cell Biology I
  17. 2025, Graduate Education (Master's Program) , 4Term, Applied Molecular Cell Biology II

Research Activities

Academic Papers

  1. Cloning and expression profile of the alanine aminotransferase gene from kuruma shrimp Penaeus japonicus exposed to different salinities, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 341(5), 615-626, 202406
    Link to Paper Search Results by DOI
  2. The potential for egg-guarding care in females of the damselfish, Dascyllus reticulatus, in the absence of uniparental male care, JOURNAL OF FISH BIOLOGY, 104(4), 979-988, 202404
    Link to Paper Search Results by DOI
  3. ★, Role of cell proliferation in strobilation of moon jellyfish Aurelia coerulea, FISHERIES SCIENCE, 90(2), 179-190, 202403
    Link to Paper Search Results by DOI
  4. A newly identified enzyme from Japanese common squid Todarodes pacificus has the ability to biosynthesize D -aspartate, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 750, 202312
    Link to Paper Search Results by DOI
  5. 4-Methoxy-2,2'-bipyrrole-5-carbaldehyde, a biosynthetic intermediate of bipyrrole-containing natural products from the Streptomyces culture, arrests the strobilation of moon jellyfish Aurelia coerulea, FRONTIERS IN MARINE SCIENCE, 10, 20230824
    Link to Paper Search Results by DOI
  6. Cloning of glutamine synthetase gene from abdominal muscle of kuruma shrimp Marsupenaeus japonicus and its expression profile, FISHERIES SCIENCE, 89(2), 215-222, 202303
    Link to Paper Search Results by DOI
  7. Changes in metabolite concentrations in the abdominal muscle of the kuruma shrimp Marsupenaeus japonicus in response to different salinities, FISHERIES SCIENCE, 87(3), 383-401, 20210501
    Link to Paper Search Results by DOI
  8. Screening for substances that regulate strobilation of the moon jellyfish, Aurelia coerulea, Aquabiology, 41(1), 47-53, 20190101
  9. ★, Molecular characterization of aspartylglucosaminidase, a lysosomal hydrolase upregulated during strobilation in the moon jellyfish, Aurelia aurita., BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 81(5), 938-950, 20170213
    Link to Paper Search Results by DOI
  10. Characterization of clonal polyp strains established from Aurelia sp. inhabiting the Seto Inland Sea of Japan, Biosphere Sci., 54, 45-54, 20151201
  11. Molecular Cloning and Expression Profile of Sex-specific Genes, Figla and Dmrt1, in the Protogynous Hermaphroditic Fish, Halichoeres poecilopterus, ZOOLOGICAL SCIENCE, 29(10), 690-701, 20121001
    Link to Paper Search Results by DOI
  12. ★, Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish, Aurelia aurita, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 76(7), 1397-1400, 20120701
    Link to Paper Search Results by DOI
  13. Ovarian degeneration during the female-to-male sex change in the protogynous hermaphroditic fish, Halichoeres poecilopterus, ICHTHYOLOGICAL RESEARCH, 59(3), 276-281, 20120701
    Link to Paper Search Results by DOI
  14. Ten novel polymorphic microsatellite loci of Red-spotted grouper (Epinephelus akaara) revealed from full-sib progeny and unrelated individuals, CONSERVATION GENETICS RESOURCES, 3(4), 613-616, 20111001
    Link to Paper Search Results by DOI
  15. Phylogenetic relationship of two Mola sunfishes (Tetraodontiformes: Molidae) occurring around the coast of Japan, with notes on their geographical distribution and morphological characteristics, ICHTHYOLOGICAL RESEARCH, 56(3), 232-244, 20090701
    Link to Paper Search Results by DOI
  16. Examination of the ability of gonadal sex change in primary males of the diandric wrasses Halichoeres poecilopterus and Halichoeres tenuispinis: estrogen implantation experiments, Zoological Science, 25(2), 220-224, 20080201
  17. Social control of terminal phase transition in primary males of the diandric wrasse, Halichoeres poecilopterus (Pisces: Labridae), Journal of Ethology, 25(1), 57-61, 20070401
  18. ★, Cloning of full-length cDNA of teleost corticotropin-releasing hormone precursor by improved inverse PCR, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 70(8), 1983-1986, 20060801
    Link to Paper Search Results by DOI
  19. Phylogenetic analysis among populations of the ocean sunfish Mola mola (Molidae) around the Japan coast, based on the mitochondrial DNA sequences., 13, 171-174, 20050401
  20. Coexistence of two clades of the ocean sunfish Mola mola (Molidae) around Japan coast., Jpn. J. Ichthyol., 52(1), 35-39, 20050401
  21. Molecular cloning of the prothoracicotropic hormone from the tobacco hornworm, Manduca sexta, INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 33(8), 795-801, 20030801
    Link to Paper Search Results by DOI
  22. Expression analysis of the lingerer gene in the larval central nervous system of Drosophila melanogaster., J. Neurogenet., 17, 117-137, 20030401
  23. ★, lingerer, a Drosophila gene involved in initiation and termination of copulation, encodes a set of novel cytoplasmic proteins., Genetics, 162(4), 1775-1789, 20021201
  24. Molecular characterization of a novel nuclear transglutaminase that is expressed during starfish embryogenesis, EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(7), 1957-1967, 20020401
    Link to Paper Search Results by DOI
  25. Genomic structure of a Drosophila melanogaster gene, Dglt-1, encoding a glutamate transporter and analyses of the spatial distribution of the transcript., J. Biochem. Molec. Biol. Biophys., 5, 31-36, 20010101
  26. Cloning and characterization of a Drosophila melanogaster cDNA encoding a glutamate transporter., Biosci. Biotech. Biochem., 63(11), 2042-2044, 19991101
  27. Neural inactivation of sex pheromone production in mated females of the silkworm moth, Bombyx mori ., Zool. Sci., 13(1), 27-33, 19960101
  28. Characterization of a Bombyx mori cDNA encoding a novel member of the attacin family of insect antibacterial proteins., Insect Biochem. Molec. Biol., 25(3), 385-392, 19950301
  29. Structure and activity of Bombyx PBAN., Arch. Insect Biochem. Physiol., 25(4), 261-270, 19930701
  30. Effects of several peptides with Pro-Arg-Leu-NH2 C-terminal sequence on invertebrate muscles., Comp. Biochem. Physiol. C, 105(3), 471-477, 19930701
  31. Active conformation of the pyrokinin/PBAN neuropeptide family for pheromone biosynthesis in the silkworm., Biochem. Biophys. Res. Commun., 193(2), 661-666, 19930601
  32. Structure-activity relationship and metabolism of pheromone biosynthesis activating neuropeptide (PBAN) from the silkmoth, Bombyx mori., Peptide Chemistry 1991, 221-226, 19920401
  33. N-terminal modified analogs of C-terminal fragments of PBAN with pheromonotropic activity., Insect Biochem. Molec. Biol., 22(4), 399-403, 19920401
  34. Cross-activity between pheromone biosynthesis activating neuropeptide (PBAN) and myotropic pyrokinin insect peptides., Biosci. Biotech. Biochem., 56(1), 167-168, 19920101
  35. Structure-activity relationship of pheromone biosynthesis activating neuropeptide (PBAN) from the silkmoth, Bombyx mori., Peptide Chemistry 1990, 251-254, 19910401

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, Chemical genetic study on segmentation in metamorphosis of moon jellyfish, 2024, 2026
  2. KAKENHI, 2019, 2021
  3. KAKENHI, 2016, 2019
  4. KAKENHI, 2016, 2018
  5. KAKENHI, 2012, 2015
    Permalink
  6. KAKENHI, Experimental study on potential plasticity of the care-taker' s sex in fishes, 2008, 2010
    Permalink
  7. KAKENHI, 2004, 2006
    Permalink
  8. KAKENHI, 2002, 2003
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  9. KAKENHI(Grant-in-Aid for Scientific Research (C)), Identification of signaling molecules that control the metamorphosis in the moon jellyfish by chemical genetics, 2020, 2023

Social Activities

Organizing Academic Conferences, etc.

  1. THE 61st SYMPOSIUM ON THE CHEMISTRY OF NATURAL PRODUCTS, 2019/09, 2019/09

History as Peer Reviews of Academic Papers

  1. 2021, Fisheries Science, Others, reviewer, 1
  2. 2019, Fisheries Science, Others, reviewer, 1
  3. 2017, Bioscience, Biotechnology, and Biochemistry, Others, reviewer, 2
  4. 2016, PeerJ, Others, reviewer, 1
  5. 2020, Bioscience, Biotechnology, and Biochemistry, Others, reviewer, 1
  6. 2021, Aquaculture Science, Others, reviewer, 1
  7. 2020, Kuroshio Biosphere, Others, reviewer, 1