SACHIKO YAMASAKI

Last Updated :2025/04/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Assistant Professor

Basic Information

Major Professional Backgrounds

  • 2024/02/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Assistant Professor
  • 2007/04/01, 2007/04/30, Hiroshima University Hospital, Oral surgery, Clinical Resident
  • 2008/04/01, 2009/03/31, Hiroshima University Hospital, Oral surgery, Clinical Fellow
  • 2011/10/01, 2011/10/31, Hiroshima University Hospital, Oral surgery, Clinical staff
  • 2012/04/01, 2014/09/30, Hiroshima University Hospital, Oral surgery, Clinical Fellow
  • 2014/10/01, 2024/01/31, Hiroshima University, Hospital Oral surgery, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2008/04, 2012/03

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Research Keywords

  • stem cell
  • Regenerative medicine

Affiliated Academic Societies

  • Japan Society for Head and Neck Cancer
  • Japanese Society of Oral Oncology
  • Japanese Society of Oral and Maxillofacial Surgeons
  • Japanese Stomatological Society
  • The Hiroshima University Dental Society
  • Society for In Vitro Biology
  • International Society for Stem Cell Research
  • Japanese Society of Oral Medicine

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, 4Term, Overview of Dentistry
  2. 2025, Undergraduate Education, 2Term, Topics in Dental Research II
  3. 2025, Undergraduate Education, 3Term, Stomatognathic Function
  4. 2025, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
  5. 2025, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
  6. 2025, Undergraduate Education, First Semester, Dental Research Practices I
  7. 2025, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine III
  8. 2025, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine IV
  9. 2025, Undergraduate Education, Second Semester, Dental Research Practices II
  10. 2025, Undergraduate Education, 2Term, Advanced Course in Applied Oral Biology and Medicine
  11. 2025, Undergraduate Education, 2Term, Advanced Course in Oral and Maxillofacial Medicine
  12. 2025, Undergraduate Education, First Semester, Dental Research Practices III
  13. 2025, Undergraduate Education, Academic Year, Clinical Practice (Oral Surgery I)
  14. 2025, Undergraduate Education, Second Semester, Clinical Practice on Oral Health
  15. 2025, Undergraduate Education, Intensive, Clinical Practice on Oral Health
  16. 2025, Undergraduate Education, Intensive, Clinical Practice on Oral Health Management

Research Activities

Academic Papers

  1. Trend Survey and Case Study of Oral Cancer Patients Visiting the Department of Oral and Maxillofacial Surgery at Hiroshima University Hospital, The journal of Hiroshima University Dental Society, 55(1), 9-16, 20230101
  2. Oral surgery under general anesthesia in a patient with catecholaminergic polymorphic ventricular tachycardia: A case report, ORAL SCIENCE INTERNATIONAL, 21(2), 275-279, 202405
    Link to Paper Search Results by DOI
  3. Two case reports of medication-related osteonecrosis of the jaw with mandibular reconstruction using a fully customized "Cosmofix®" plate, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 36(3), 347-353, 202405
    Link to Paper Search Results by DOI
  4. A Study of the Prognostic Factors for Late Cervical Lymph Node Metastasis and Distant Metastasis in Patients with cT1-2N0 Tongue Cancer, JOURNAL OF CLINICAL MEDICINE, 13(4), 202402
    Link to Paper Search Results by DOI
  5. Transformation of an odontogenic keratocyst into a solid variant of odontogenic keratocyst/keratoameloblastoma during long-term follow-up: A case report, MOLECULAR MEDICINE REPORTS, 29(3), 202403
    Link to Paper Search Results by DOI
  6. Clinical significance of integrin αV and β superfamily members and focal adhesion kinase activity in oral squamous cell carcinoma: a retrospective observational study, PATHOLOGY & ONCOLOGY RESEARCH, 30, 20240118
    Link to Paper Search Results by DOI
  7. Clinical Efficacy and Safety of Lidocaine Tape for Topical Anesthesia of the Oral Mucosa: A Preliminary Controlled Trial, DENTISTRY JOURNAL, 11(12), 202312
    Link to Paper Search Results by DOI
  8. A case of recurrent lip cancer with middle skull base invasion with response to cetuximab and paclitaxel combination chemotherapy after nivolumab monotherapy, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 36(1), 71-76, 202401
    Link to Paper Search Results by DOI
  9. Molecular and histopathological findings in malignant transformation of proliferative verrucous leukoplakia that was successfully controlled for 15 years, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 36(1), 153-158, 202401
    Link to Paper Search Results by DOI
  10. Tumor-Infiltrating CD45RO(+) Memory Cells Are Associated with Favorable Prognosis in Oral Squamous Cell Carcinoma Patients, CANCERS, 15(8), 202304
    Link to Paper Search Results by DOI
  11. A rare case of pleomorphic adenoma originating at the tip of palatine uvula, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 34(6), 784-787, 202211
    Link to Paper Search Results by DOI
  12. A rare case of pleomorphic adenoma originating at the tip of palatine uvula., Journal of Oral and Maxillofacial Surgery, Medicine, and Patholog, 2022
    Link to Paper Search Results by DOI
  13. Identification of a familial cleidocranial dysplasia with a novel RUNX2 mutation and establishment of patient-derived induced pluripotent stem cells, ODONTOLOGY, 110(3), 444-451, 202207
    Link to Paper Search Results by DOI
  14. Two Cases of Temporomandibular Synovial Chondromatosis Associated with Gli1 Gene Mutation, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 19(8), 202204
    Link to Paper Search Results by DOI
  15. Identification of a Cowden syndrome patient with a novel PTEN mutation and establishment of patient‑derived induced pluripotent stem cells, In Vitro Cellular & Developmental Biology - Animal, 1-10, 20220103
    Link to Paper Search Results by DOI
  16. Identification of a familial cleidocranial dysplasia with a novel RUNX2 mutation and establishment of patient‑derived induced pluripotent stem cells, Odontology, 2021, 1-8, 20211115
    Link to Paper Search Results by DOI
  17. A Clinical Study of Salivary Gland Tumors in the Department of Oral and Maxillofacial Surgery at Hiroshima University Hospital, 53(1), 16-22, 202106
  18. MICA A5.1 homozygous genotype is associated with a risk for early-onset oral cancer, ORAL ONCOLOGY, 116, 202105
    Link to Paper Search Results by DOI
  19. Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 56(10), 888-895, 202012
    Link to Paper Search Results by DOI
  20. Oral squamous cell carcinoma of the tongue dorsum with multiple cancer-associated mutations in the TP53 gene, Oral Oncology, 20200512
    Link to Paper Search Results by DOI
  21. Induction of integration-free human-induced pluripotent stem cells under serum- and feeder-free conditions, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 56(1), 85-95, 202001
    Link to Paper Search Results by DOI
  22. Induction of integration-free human induced pluripotent stem cells under serum-​ and feeder-free conditions, In Vitro Cell Dev Biol Anim, 56(1), 85-95, 2019
  23. Establishment and Characterization of Disease-specific Human iPSCs in Serum-, Integration- and Feeder-free Cultures., IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 55, S6-S6, 2019
  24. A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017), PATHOLOGY INTERNATIONAL, 67(7), 365-369, 201707
    Link to Paper Search Results by DOI
  25. Disseminated intravascular coagulation (DIC) and the idiopathic thrombocytopenic purpura (ITP) diagnosed by abnormal intraoral hematoma, Japanese Society of Oral Medicine, 23(1), 28-33, 201706
  26. Generation of cleidocranial dysplasia-specific human induced pluripotent stem cells in completely serum-, feeder-, and integration-free culture, In Vitro Cell Dev Biol Anim, 52(2), 252-264, 201602
    Link to Paper Search Results by DOI
  27. Generation and maintenance of human induced pluripotent stem cells in serum-free and feeder-free culture condition-comparison of various target cells and virus vectors., Jpn. J. Tissue Cult. Soc. Dent. Res, 25(1), 21-22, (2015), 1(25), 21-22, 2015
  28. Establishment and long-term culture of iPS cells from peripheral blood mononuclear cells with sendai virus vector in serum-, feeder cell-free complete defined medium., Jpn. J. Tissue Cult. Soc. Dent. Res 24(1), 51-52, (2015), 24(1), 51, 2014
  29. ★, Generation of Human Induced Pluripotent Stem(iPS)Cells in Serum- and Feeder-Free Defined Culture and TGF-b1 Regulation of Pluripotency., PLoS ONE, 9(1)(e87151), 2014
    Link to Paper Search Results by DOI
  30. Long-term serial cultivation of mouse induced pluripotent stem cells in serum-free and feeder-free defined medium., Int J Dev Biol., 57(9-10), 715-724, 2013

Invited Lecture, Oral Presentation, Poster Presentation

  1. Investigation of Local Recurrence of Oral Cancer: Relationship with Anatomical Landmarks in Cases of Backward Progression, Nanako Ito, Koichi Koizumi, Tomoaki Shintani, Yasuyuki Asada, Taeko Fukutani, Atsuko Hamada, Sachiko Yamasaki, Tomoaki Hamana, Yukio Yoshioka, Souichi Yanamoto, 9th World Congress of the International Academy of Oral Oncology (IAOO 2023), 2023/11/01, Without Invitation, English, IAOO, Incheon
  2. Reconstruction of the mandible by full custom-made titanium plate Cosmofix®, Sachiko YAMASAKI, Yukio YOSHIOKA, Taeko FUKUTANI, Yuko SHINTAKU, Koichi KOIZUMI, Tomonao AIKAWA, Souichi YANAMOTO, 56th Annual Meeting of Hiroshima University Dental Society, 2023/06/03, Without Invitation, English
  3. A case of recurrent lip cancer with middle skull base invasion responding to cetuximab + paclitaxel combination chemotherapy after nivolumab monotherapy, 2022/11/05, Without Invitation, Japanese
  4. A Case of Oral Squamous Cell Carcinoma of the Tongue Dorsum with Multiple Cancer associated with Mutations of the TP53 Gene, 2020/11/14, Without Invitation, English
  5. Establishment and Characterization of Disease-specific Human iPSCs in Serum-, Integration- and Feeder-free Cultures., Atsuko Hamada, Y. Nakase1, F. Obayashi1,T. Fukutani1, H. Nakatao1, E. Sakaue1, S. Yamasaki1, T.Kanda1, K. Koizumi2, Y. Yoshioka2, R. Tani1, S. Toratani2,J. D. Sato, and T. Okamoto, in vitro bilogy meeting 2019, 2019/06/08, With Invitation, English, Society for in vitro biology, Tampa florida, USA
  6. A clinical study on Adolescent and Young Adult (AYA) patients with oral cancer, Y. YOSHIOKA, T. SAKAUE, K. MATSUI, K. TSUSHIMA, F. OBAYASHI, A. HAMADA, S. YAMASAKI, T. HAMANA, K. SUMI, T. KANDA, K. KOIZUMI, R. TANI, Y. HAYASHIDO, H. SASAHARA, S. TORATANI, T. OKAMOTO, The 51th Annual Meeting of Hiroshima University Dental Society, 2018/06/09, Without Invitation, English, Hiroshima University Dental Society, Hiroshima
  7. Genetic diagnosis of Neurofibromatosis type I (von Recklinghausen's disease) and establishment of NF1-specific induced pluripotent stem cells (iPSCs) for the study of disease mechanisms, Taeko FUKUTANI, A. HAMADA 1,H. NAKATAO 1,F. OBAYASHI 1,S. YAMASAKI 1, T. KANDA 1,K. KOIZUMI 2,S. TORATANI 2,T. OKAMOTO, 7th Hiroshima Conference on Education and Science in Dentistry, 2018/03/30, Without Invitation, English, Hiroshima Conference on Education and Science in Dentistry, Hiroshima
  8. Diversity analysis of gut and oral microbiome in oral cancer patients and beneficial effects of probiotics, Kensaku MATSUI, Ryouji TANI, Sachiko YAMASAKI, Atsuko HAMADA, Takefumi MISHIMA, Kaori UCHISAKO, Hisako SASAHARA, Shigeaki TORATANI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, Hiroshima univ.
  9. Genetic diagnosis of Neurofibromatosis type I (von Recklinghausen's disease) and establishment of NF1-specific induced pluripotent stem cells (iPSCs) in virus integration-, feeder-, and serum-free defined culture for disease model study, Taeko Fukutani, Atsuko HAMADA, Hirotaka NAKATAO, Fumitaka OBAYASHI, Sachiko YAMASAKI, Taku KANDA, Kouichi KOIZUMI, Shigeaki TORATANI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, HIroshima University
  10. "Genetic diagnosis of Cowden Syndrome (CS) and establishment of CS-specific induced pluripotent stem cells (iPSC) in virus integration-, feeder-, and serum-free defined culture for disease model study", Fumitaka Obayashi, Atsuko Hamada, Hirotaka Nakatao, Taeko Fukutani, Eri Akagi, Sachiko Yamasaki, Taku Kanda, Shigeaki Toratani, Tetsuji Okamoto, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, HIroshima University
  11. Generation of disease specific-iPSCs in virus integration-, feeder-, and serum-free defined culture, and their use for disease model study, Atsuko HAMADA, Hirotaka NAKATAO, Fumitaka OHBAYASHI, Taeko HUKUTANI, Sachiko YAMASAKI ,Kouichi KOIZUMI, Shigeaki TORATNI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, Hiroshima University
  12. Function of rbc2lcn Lectin-recognizing Glycoprotein-positive Cells in Squamous Cell Carcinoma Cell Lines, Hirotaka Nakatao, 2017 In Vitro Biology Meeting, 2017, Without Invitation, Japanese, society for in vitro biology, Raleigh, North Carolina,USA
  13. Establishment and characterization of normal and disease-specific human iPSCs in serum-, integration- and feeder-free culture., Sachiko Yamasaki, The 14th international conference on cellular endocrinology, 2016/11/13, With Invitation, English, The Society for In Vitro Biology, San Diego California
  14. Establishment and Characterization of Normal and Disease-specific of Human iPSC in Serum-, Integration- and Feeder-free Cultures., Sachiko Yamasaki, Plenary Symposium on Infinite Potential of Stem Cells, 2016 World Congress on In Vitro Biology, 2016/06/14, With Invitation, English, Plenary Symposium on Infinite Potential of Stem Cells,, San Diego, California,USA
  15. Generation and maintenance of integration-free human induced pluripotent stem (hiPS) cells from peripheral blood mononuclear cells in serum- and feeder-free growth factor defined medium, Sachiko Yamasaki, 2015 in vitro biology biology meeting, 2015/06/03, Without Invitation, English, Society for In vitro biology, Tucson, Arizona
  16. Generation and maintenance of human induced pluripotent stem cells in serum-free and feeder-free culture conditions using Sendai virus vectors, 2014/05/31, Without Invitation, English, Savannah, Georgia, USA
  17. Reprogramming efficiencies of DPCs-derived hiPS cells with various virus vectors in serum- and feeder-free culture conditions., Eri AKAGI, Sachiko YAMASAKI, Atsuko HAMADA, Yuki TAGUCHI, Hanae MUKASA, Manami OHTAKA, Ken NISHIMURA, Mahito NAKANISHI, and Tetsuji OKAMOTO, 2014 world Forum on Biology, 2014/05/31, Without Invitation, English, Savannah, Georgia, USA
  18. Generation of human induced pluripotent stem (iPS) cells in serum- and feeder-free defined culture from dental pulp cells., Sachiko Yamasaki, 5th Hiroshima conference on Education and Science in Dentistry, 2013/10/12, With Invitation, English, Hiroshima, Japan
  19. Generation of human induced pluripotent stem (iPS) cells in serum- and feeder-free defined culture from fetal lung fibroblasts and dental pulp cells derived from a patient with cleidocranial dysplasia., S Yamasaki, A Shimamoto, H Tahara, T Okamoto, 2012 World congress on In Vitro Biology, 2012/06/03, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. 2023, 2027
  2. 2018, 2022
  3. 2017
  4. KAKENHI, 2016, 2017
  5. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2015/01/01, 2015/12/31
  6. 2015
  7. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2015/01/01, 2015/12/31
  8. KAKENHI, 2014, 2015
    Permalink
  9. 2014/04/01
  10. KAKENHI, Generation of disease-specific human induced pluripotent stem (iPS) cells of a patient with Cleidocranial dysplasia in serum- and feeder-free defined culture., 2012, 2013
    Permalink
  11. 2018, 2018
  12. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2018, 2022