SACHIKO YAMASAKI

Last Updated :2024/05/15

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Assistant Professor

Basic Information

Major Professional Backgrounds

  • 2024/02/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Assistant Professor
  • 2008/04/01, 2009/03/31, Hiroshima University Hospital, Oral surgery, Clinical Fellow
  • 2011/10/01, 2011/10/31, Hiroshima University Hospital, Oral surgery, Clinical staff
  • 2012/04/01, 2014/09/30, Hiroshima University Hospital, Oral surgery, Clinical Fellow
  • 2014/10/01, 2024/01/31, Hiroshima University, Hospital Oral surgery, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2008/04, 2012/03
  • Hiroshima University, SCHOOL OF DENTISTRY, Japan, 2001/04, 2007/03

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Surgical dentistry

Research Keywords

  • stem cell
  • Regenerative medicine

Affiliated Academic Societies

  • Japan Society for Head and Neck Cancer
  • Japanese Society of Oral Oncology
  • Japanese Society of Oral and Maxillofacial Surgeons
  • Japanese Stomatological Society
  • The Hiroshima University Dental Society
  • Society for In Vitro Biology
  • International Society for Stem Cell Research
  • Japanese Society of Oral Medicine

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 2Term, Topics in Dental Research II
  2. 2024, Undergraduate Education, 3Term, Stomatognathic Function
  3. 2024, Undergraduate Education, 1Term, Oral and Maxillofacial Surgery I
  4. 2024, Undergraduate Education, 2Term, Oral and Maxillofacial Surgery II
  5. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  6. 2024, Undergraduate Education, 3Term, Basic Practice of Oral and Maxillofacial Medicine I
  7. 2024, Undergraduate Education, 4Term, Basic Practice of Oral and Maxillofacial Medicine II
  8. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  9. 2024, Undergraduate Education, 2Term, Advanced Course in Applied Oral Biology and Medicine
  10. 2024, Undergraduate Education, 2Term, Advanced Course in Oral and Maxillofacial Medicine
  11. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  12. 2024, Undergraduate Education, Academic Year, Clinical Practice (Oral Surgery I)
  13. 2024, Undergraduate Education, Second Semester, Clinical Practice on Oral Health
  14. 2024, Undergraduate Education, Intensive, Clinical practice on oral health
  15. 2024, Undergraduate Education, Intensive, Clinical Practice on Oral Health Management

Research Activities

Academic Papers

  1. Tumor-Infiltrating CD45RO(+) Memory Cells Are Associated with Favorable Prognosis in Oral Squamous Cell Carcinoma Patients, CANCERS, 15(8), 202304
    Link to Paper Search Results by DOI
  2. A rare case of pleomorphic adenoma originating at the tip of palatine uvula, JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY MEDICINE AND PATHOLOGY, 34(6), 784-787, 202211
    Link to Paper Search Results by DOI
  3. Identification of a familial cleidocranial dysplasia with a novel RUNX2 mutation and establishment of patient-derived induced pluripotent stem cells, ODONTOLOGY, 110(3), 444-451, 202207
    Link to Paper Search Results by DOI
  4. Two Cases of Temporomandibular Synovial Chondromatosis Associated with Gli1 Gene Mutation, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 19(8), 202204
    Link to Paper Search Results by DOI
  5. Identification of a Cowden syndrome patient with a novel PTEN mutation and establishment of patient‑derived induced pluripotent stem cells, In Vitro Cellular & Developmental Biology - Animal, 1-10, 20220103
    Link to Paper Search Results by DOI
  6. Identification of a familial cleidocranial dysplasia with a novel RUNX2 mutation and establishment of patient‑derived induced pluripotent stem cells, Odontology, 2021, 1-8, 20211115
    Link to Paper Search Results by DOI
  7. A Clinical Study of Salivary Gland Tumors in the Department of Oral and Maxillofacial Surgery at Hiroshima University Hospital, 53(1), 16-22, 202106
  8. MICA A5.1 homozygous genotype is associated with a risk for early-onset oral cancer, ORAL ONCOLOGY, 116, 202105
    Link to Paper Search Results by DOI
  9. Induction of Noonan syndrome-specific human-induced pluripotent stem cells under serum-, feeder-, and integration-free conditions, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 56(10), 888-895, 202012
    Link to Paper Search Results by DOI
  10. Oral squamous cell carcinoma of the tongue dorsum with multiple cancer-associated mutations in the TP53 gene, Oral Oncology, 20200512
    Link to Paper Search Results by DOI
  11. Induction of integration-free human-induced pluripotent stem cells under serum- and feeder-free conditions, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 56(1), 85-95, 202001
    Link to Paper Search Results by DOI
  12. Induction of integration-free human induced pluripotent stem cells under serum-​ and feeder-free conditions, In Vitro Cell Dev Biol Anim, 56(1), 85-95, 2019
  13. Establishment and Characterization of Disease-specific Human iPSCs in Serum-, Integration- and Feeder-free Cultures., IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 55, S6-S6, 2019
  14. A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017), PATHOLOGY INTERNATIONAL, 67(7), 365-369, 201707
    Link to Paper Search Results by DOI
  15. Disseminated intravascular coagulation (DIC) and the idiopathic thrombocytopenic purpura (ITP) diagnosed by abnormal intraoral hematoma, Japanese Society of Oral Medicine, 23(1), 28-33, 201706
  16. Generation of cleidocranial dysplasia-specific human induced pluripotent stem cells in completely serum-, feeder-, and integration-free culture, In Vitro Cell Dev Biol Anim, 52(2), 252-264, 201602
    Link to Paper Search Results by DOI
  17. Generation and maintenance of human induced pluripotent stem cells in serum-free and feeder-free culture condition-comparison of various target cells and virus vectors., Jpn. J. Tissue Cult. Soc. Dent. Res, 25(1), 21-22, (2015), 1(25), 21-22, 2015
  18. Establishment and long-term culture of iPS cells from peripheral blood mononuclear cells with sendai virus vector in serum-, feeder cell-free complete defined medium., Jpn. J. Tissue Cult. Soc. Dent. Res 24(1), 51-52, (2015), 24(1), 51, 2014
  19. ★, Generation of Human Induced Pluripotent Stem(iPS)Cells in Serum- and Feeder-Free Defined Culture and TGF-b1 Regulation of Pluripotency., PLoS ONE, 9(1)(e87151), 2014
    Link to Paper Search Results by DOI
  20. Long-term serial cultivation of mouse induced pluripotent stem cells in serum-free and feeder-free defined medium., Int J Dev Biol., 57(9-10), 715-724, 2013

Invited Lecture, Oral Presentation, Poster Presentation

  1. A Case of Oral Squamous Cell Carcinoma of the Tongue Dorsum with Multiple Cancer associated with Mutations of the TP53 Gene, 2020/11/14, Without Invitation, English
  2. Establishment and Characterization of Disease-specific Human iPSCs in Serum-, Integration- and Feeder-free Cultures., Atsuko Hamada, Y. Nakase1, F. Obayashi1,T. Fukutani1, H. Nakatao1, E. Sakaue1, S. Yamasaki1, T.Kanda1, K. Koizumi2, Y. Yoshioka2, R. Tani1, S. Toratani2,J. D. Sato, and T. Okamoto, in vitro bilogy meeting 2019, 2019/06/08, With Invitation, English, Society for in vitro biology, Tampa florida, USA
  3. A clinical study on Adolescent and Young Adult (AYA) patients with oral cancer, Y. YOSHIOKA, T. SAKAUE, K. MATSUI, K. TSUSHIMA, F. OBAYASHI, A. HAMADA, S. YAMASAKI, T. HAMANA, K. SUMI, T. KANDA, K. KOIZUMI, R. TANI, Y. HAYASHIDO, H. SASAHARA, S. TORATANI, T. OKAMOTO, The 51th Annual Meeting of Hiroshima University Dental Society, 2018/06/09, Without Invitation, English, Hiroshima University Dental Society, Hiroshima
  4. Genetic diagnosis of Neurofibromatosis type I (von Recklinghausen's disease) and establishment of NF1-specific induced pluripotent stem cells (iPSCs) for the study of disease mechanisms, Taeko FUKUTANI, A. HAMADA 1,H. NAKATAO 1,F. OBAYASHI 1,S. YAMASAKI 1, T. KANDA 1,K. KOIZUMI 2,S. TORATANI 2,T. OKAMOTO, 7th Hiroshima Conference on Education and Science in Dentistry, 2018/03/30, Without Invitation, English, Hiroshima Conference on Education and Science in Dentistry, Hiroshima
  5. Diversity analysis of gut and oral microbiome in oral cancer patients and beneficial effects of probiotics, Kensaku MATSUI, Ryouji TANI, Sachiko YAMASAKI, Atsuko HAMADA, Takefumi MISHIMA, Kaori UCHISAKO, Hisako SASAHARA, Shigeaki TORATANI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, Hiroshima univ.
  6. Genetic diagnosis of Neurofibromatosis type I (von Recklinghausen's disease) and establishment of NF1-specific induced pluripotent stem cells (iPSCs) in virus integration-, feeder-, and serum-free defined culture for disease model study, Taeko Fukutani, Atsuko HAMADA, Hirotaka NAKATAO, Fumitaka OBAYASHI, Sachiko YAMASAKI, Taku KANDA, Kouichi KOIZUMI, Shigeaki TORATANI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, HIroshima University
  7. "Genetic diagnosis of Cowden Syndrome (CS) and establishment of CS-specific induced pluripotent stem cells (iPSC) in virus integration-, feeder-, and serum-free defined culture for disease model study", Fumitaka Obayashi, Atsuko Hamada, Hirotaka Nakatao, Taeko Fukutani, Eri Akagi, Sachiko Yamasaki, Taku Kanda, Shigeaki Toratani, Tetsuji Okamoto, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, HIroshima University
  8. Generation of disease specific-iPSCs in virus integration-, feeder-, and serum-free defined culture, and their use for disease model study, Atsuko HAMADA, Hirotaka NAKATAO, Fumitaka OHBAYASHI, Taeko HUKUTANI, Sachiko YAMASAKI ,Kouichi KOIZUMI, Shigeaki TORATNI, Tetsuji OKAMOTO, the 15th international conference on cellual endocrinology, 2017/10/09, Without Invitation, English, Hiroshima University
  9. Function of rbc2lcn Lectin-recognizing Glycoprotein-positive Cells in Squamous Cell Carcinoma Cell Lines, Hirotaka Nakatao, 2017 In Vitro Biology Meeting, 2017, Without Invitation, Japanese, society for in vitro biology, Raleigh, North Carolina,USA
  10. Establishment and characterization of normal and disease-specific human iPSCs in serum-, integration- and feeder-free culture., Sachiko Yamasaki, The 14th international conference on cellular endocrinology, 2016/11/13, With Invitation, English, The Society for In Vitro Biology, San Diego California
  11. Establishment and Characterization of Normal and Disease-specific of Human iPSC in Serum-, Integration- and Feeder-free Cultures., Sachiko Yamasaki, Plenary Symposium on Infinite Potential of Stem Cells, 2016 World Congress on In Vitro Biology, 2016/06/14, With Invitation, English, Plenary Symposium on Infinite Potential of Stem Cells,, San Diego, California,USA
  12. Generation and maintenance of integration-free human induced pluripotent stem (hiPS) cells from peripheral blood mononuclear cells in serum- and feeder-free growth factor defined medium, Sachiko Yamasaki, 2015 in vitro biology biology meeting, 2015/06/03, Without Invitation, English, Society for In vitro biology, Tucson, Arizona
  13. Generation and maintenance of human induced pluripotent stem cells in serum-free and feeder-free culture conditions using Sendai virus vectors, 2014/05/31, Without Invitation, English, Savannah, Georgia, USA
  14. Reprogramming efficiencies of DPCs-derived hiPS cells with various virus vectors in serum- and feeder-free culture conditions., Eri AKAGI, Sachiko YAMASAKI, Atsuko HAMADA, Yuki TAGUCHI, Hanae MUKASA, Manami OHTAKA, Ken NISHIMURA, Mahito NAKANISHI, and Tetsuji OKAMOTO, 2014 world Forum on Biology, 2014/05/31, Without Invitation, English, Savannah, Georgia, USA
  15. Generation of human induced pluripotent stem (iPS) cells in serum- and feeder-free defined culture from dental pulp cells., Sachiko Yamasaki, 5th Hiroshima conference on Education and Science in Dentistry, 2013/10/12, With Invitation, English, Hiroshima, Japan
  16. Generation of human induced pluripotent stem (iPS) cells in serum- and feeder-free defined culture from fetal lung fibroblasts and dental pulp cells derived from a patient with cleidocranial dysplasia., S Yamasaki, A Shimamoto, H Tahara, T Okamoto, 2012 World congress on In Vitro Biology, 2012/06/03, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. 2018, 2022
  2. 2017
  3. KAKENHI, 2016, 2017
  4. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2015/01/01, 2015/12/31
  5. 2015
  6. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2015/01/01, 2015/12/31
  7. KAKENHI, 2014, 2015
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  8. 2014/04/01
  9. KAKENHI, Generation of disease-specific human induced pluripotent stem (iPS) cells of a patient with Cleidocranial dysplasia in serum- and feeder-free defined culture., 2012, 2013
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  10. 2018, 2018
  11. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2018, 2022