KOTA TAKEMOTO

Last Updated :2024/12/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medical), Assistant Professor
Web Site
http://home.hiroshima-u.ac.jp/jibika/
E-mail
kota61hiroshima-u.ac.jp
Other Contact Details
Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan., Japan
TEL : (+81)82-257-5252 FAX : (+81)82-257-5254
Self-introduction
In the fields of rhinology and allergology, I am engaged in research on elucidating pathologies and developing new treatment methods.

Basic Information

Major Professional Backgrounds

  • 2014/04/01, 2016/03, JA Hiroshima General Hospital, medical intern
  • 2016/04/01, 2016/08/31, Hiroshima University, Hospital, Otorhinolaryngology, Head and Neck Surgery, medical practitioner
  • 2016/09/01, 2019/06, Higashihiroshima Medical Center, Otorhinolaryngology, Head and Neck Surgery, medical staff
  • 2019/07/01, 2023/04/30, Hiroshima University, Hospital, Otorhinolaryngology, Head and Neck Surgery, medical practitioner
  • 2023/05/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Assistant Professor

Educational Backgrounds

  • Hiroshima University, School of Medicine, Japan, 2008/04/01, 2014/03
  • Hiroshima University Graduate School, Japan, 2019/04/01, 2023/03

Academic Degrees

  • Hiroshima University

In Charge of Primary Major Programs

  • Medicine

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Otorhinolaryngology

Research Keywords

  • nose and paranasal sinuses nitric oxide nasal allergy allergy and inflammation in the upper airway endoscopic sinus surgery

Affiliated Academic Societies

  • Japan Society of Immunology, Allergology and Infection in Otorhinolaryngology
  • The Oto-Rhino-Laryngological Society of Japan
  • Japanese Society of Allergology
  • Japanese Rhinologic Society
  • Practica oto-rhino-laryngologica
  • The Society of Swallowing and Dysphagia of Japan

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 2Term, Otorhinology
  2. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Otorhinolaryngology,Head and Neck Surgery
  3. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Otorhinolaryngology,Head and Neck Surgery
  4. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Otorhinolaryngology,Head and Neck Surgery
  5. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Otorhinolaryngology,Head and Neck Surgery

Research Activities

Academic Papers

  1. Severe Type 2 Inflammation Leads to High Platelet-Activating-Factor-Associated Pathology in Chronic Rhinosinusitis with Nasal Polyps-A Hierarchical Cluster Analysis Using Bulk RNA Barcoding and Sequencing, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(4), 202402
    Link to Paper Search Results by DOI
  2. Oncostatin M's Involvement in the Pathogenesis of Chronic Rhinosinusitis: Focus on Type 1 and 2 Inflammation, BIOMEDICINES, 11(12), 202312
    Link to Paper Search Results by DOI
  3. Swallowing Exercise Evaluated Using High-Density Surface Electromyography in Patients with Head and Neck Cancer: Supplementary Analysis of an Exploratory Phase II Trial, MEDICINA-LITHUANIA, 59(12), 202312
    Link to Paper Search Results by DOI
  4. Exhaled Nitric Oxide and Olfactory Dysfunction in Patients with Asthma: Association with Chronic Rhinosinusitis, MEDICINA-LITHUANIA, 59(10), 202310
    Link to Paper Search Results by DOI
  5. Peritonsillar abscesses in infants requiring intratracheal intubation: Two case reports*, OTOLARYNGOLOGY CASE REPORTS, 24, 202209
    Link to Paper Search Results by DOI
  6. Expression of Mesenchymal Stem Cell (MSC) Markers and Differentiation Processes in Cultured Cells from Human Ethmoid Sinus and Inferior Turbinate Mucosa, Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology), 2024
  7. ★, Functional Alteration and Differential Expression of the Bitter Taste Receptor T2R38 in Human Paranasal Sinus in Patients with Chronic Rhinosinusitis, Int J Mol Sci, 24(5), 4499, 2023
  8. Co-Expression and Localization of Angiotensin-Converting Enzyme-2 (ACE2) and the Transmembrane Serine Protease 2 (TMPRSS2) in Paranasal Ciliated Epithelium of Patients with Chronic Rhinosinusitis, Am J Rhinol Allergy, 36,3, 313-322, 2022
  9. Deep Association between Transglutaminase 1 and Tissue Eosinophil Infiltration Leading to Nasal Polyp Formation and/or Maintenance with Fibrin Polymerization in Chronic Rhinosinusitis with Nasal Polyps, Int. J. Mol. Sci, 23, 21, 12955, 2022
  10. Impact of Preventive Measures on Subjective Symptoms and Antigen Sensitization against Japanese Cedar, Cypress Pollen and House Dust Mites in Patients with Allergic Rhinitis: A Retrospective Analysis in the COVID-19 Era, Atmosphere, 13, 1000, 2022
  11. Peritonsillar abscesses in infants requiring intratracheal intubation: Two case reports, Otolaryngology Case Reports, 24, 100454, 2022
  12. ★, Nitric oxide synthase-2 (CCTTT)n polymorphism is associated with local gene expression and clinical manifestations in patients with chronic rhinosinusitis, European Journal of Inflammation, 20, 1-10, 2022
  13. Distinct Gene Set Enrichment Profiles in Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Bulk RNA Barcoding and Sequencing, Int J Mol Sci, 23, 10, 5653, 2022
  14. Differential expression of angiotensin-converting enzyme-2 in human paranasal sinus mucosa in patients with chronic rhinosinusitis, J Laryngol Otol, 135, 9, 773-778, 2021
  15. The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis, Int J Mol Sci, 15,22(14), 7561, 2021
  16. Increased tissue expression of lectin-like oxidized LDL receptor-1(LOX-1) is associated with disease severity in chronic rhinosinusitis with nasal polyps, Diagnostics, 10, 246, 2020
  17. ★, Efficacy of anti-PD-1 therapy in a patient with brain metastasis of squamous cell carcinoma, Auris Nasus Larynx, 46(5), 813-817, 2019

Invited Lecture, Oral Presentation, Poster Presentation

  1. Quantitative assessment of sinus imaging patterns in patients with chronic rhinosinusitis., 42nd Congress of the International Society of Inflammation and Allergy of the Nose 24th Congress of the International Rhinologic Society, 2024/04/04, Without Invitation, English
  2. Expression and localization of the bitter taste receptor in patients with chronic rhinosinusitis, Kota Takemoto, Sachio Takeno, Takashi Ishino, Yuichiro Horibe, Takashi Oda, Chie Ishikawa, Tomohiro Kawasumi, The 61st Annual Meeting of Japanese Rhinologic Society, 2022/10/14, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. 2016
  2. 2019
  3. TAIHO PHARMACEUTICAL CO. Donation, 2022
  4. TAIHO PHARMACEUTICAL CO. Donation, 2023

Social Activities

Organizing Academic Conferences, etc.

  1. 2022/07, 2022/07
  2. 2022/07, 2022/07