KAZUYA DOI

Last Updated :2025/02/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Associate Professor or Lecturer
E-mail
kazuya17hiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Dental Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Prosthodontics / Dental materials science and

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 3Term, Prosthetic Dentistry I
  2. 2024, Undergraduate Education, 4Term, Prosthetic Dentistry II
  3. 2024, Undergraduate Education, 3Term, Removable Prosthodontics I
  4. 2024, Undergraduate Education, 4Term, Removable Prosthodontics II
  5. 2024, Undergraduate Education, 2Term, Oral Implantology
  6. 2024, Undergraduate Education, 1Term, Basic Practice of Functional and Regenerative Oral Medicine I
  7. 2024, Undergraduate Education, 2Term, Basic Practice of Functional and Regenerative Oral Medicine II
  8. 2024, Undergraduate Education, 1Term, Practice of Prosthodontic Treatment for Edentulous Patients I
  9. 2024, Undergraduate Education, 2Term, Practice of Prosthodontic Treatment for Edentulous Patients II
  10. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  11. 2024, Undergraduate Education, 3Term, Practice of Prosthodontic Treatment for Partial Edentulous Patients I
  12. 2024, Undergraduate Education, 4Term, Practice of Prosthodontic Treatment for Partial Edentulous Patients II
  13. 2024, Undergraduate Education, 3Term, Basic Practice of Dental Prosthesis I
  14. 2024, Undergraduate Education, 4Term, Basic Practice of Dental Prosthesis II
  15. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  16. 2024, Undergraduate Education, 2Term, Advanced Course in Functional and Regenerative Oral Medicine
  17. 2024, Undergraduate Education, 2Term, General Seminar on Clinical Dentistry
  18. 2024, Undergraduate Education, 2Term, Basic and clinical integrated theory
  19. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  20. 2024, Undergraduate Education, Academic Year, Clinical Practice (Denture Prosthodontics I)
  21. 2024, Undergraduate Education, Academic Year, Clinical Practice (Denture Prosthodontics II)
  22. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Advanced Prosthodontics
  23. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Advanced Prosthodontics
  24. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Advanced Prosthodontics
  25. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Advanced Prosthodontics

Research Activities

Academic Papers

  1. Histological and histomorphometric aspects of continual intermittent parathyroid hormone administration on osseointegration in osteoporosis rabbit model, PLOS ONE, 17(6), 2022
    Link to Paper Search Results by DOI
  2. Implant Stability Following Osseointegration of Dental Implants in Bone Sites Reconstructed with Novel Porous Titanium Scaffold, JOURNAL OF HARD TISSUE BIOLOGY, 31(2), 115-120, 2022
  3. Comparative Study of Surface Modification Treatment for Porous Titanium, J Oral Maxillofac Res, 11(2), e5-e5, 20200730
  4. Use of an intraoral scanner to evaluate oral health, JOURNAL OF ORAL SCIENCE, 63(3), 292-294, 20210729
    Link to Paper Search Results by DOI
  5. The development of novel bioactive porous titanium as a bone reconstruction material, RSC Advances, 10: 22684-22690, 2020., 10, 22684-22690, 20200612
  6. Development of a novel bioactive titanium membrane with alkali treatment for bone regeneration, DENTAL MATERIALS JOURNAL, 39(5), 877-882, 20200522
    Link to Paper Search Results by DOI
  7. Novel fabrication of porous titanium by a resin-impregnated titanium substitution technique for bone reconstruction, RSC ADVANCES, 9(3), 1625-1631, 20190113
    Link to Paper Search Results by DOI
  8. Effect of autoclave heat sterilization on the surface properties of the sodium titanate hydrogel layer on alkali-treated titanium membranes, J-Hiroshima Univ Dent Soc, 51(2), 85-90, 20191201
  9. Bone reconstruction therapy of nobei porous titanium, Dental Diamond, 44(5), 102-106, 20190401
  10. Histological and Bone Morphometric Evaluation of Osseointegration Aspects by Alkali Hydrothermally-Treated Implants, APPLIED SCIENCES-BASEL, 8(4), 2018
    Link to Paper Search Results by DOI
  11. Enhancement of calcification by osteoblasts cultured on hydroxyapatite surfaces with adsorbed inorganic polyphosphate, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 54(6), 449-457, 2018
    Link to Paper Search Results by DOI
  12. Stability of Implants Placed in Bone Reconstructed with Block-type Interconnected Porous Hydroxyapatite, JOURNAL OF HARD TISSUE BIOLOGY, 26(4), 393-397, 2017
  13. Effects of continual intermittent administration of parathyroid hormone on implant stability in the presence of osteoporosis: an in vivo study using resonance frequency analysis in a rabbit model, JOURNAL OF APPLIED ORAL SCIENCE, 25(5), 498-505, 2017
    Link to Paper Search Results by DOI
  14. Investigation of Effective Modification Treatments for Titanium Membranes, APPLIED SCIENCES-BASEL, 7(10), 2017
    Link to Paper Search Results by DOI
  15. Novel porous titanium structure as bone reconstruction material, PHARM STAGE, 17(5), 41-47, 2017
  16. A stability evaluation of a novel titanium dental implant/interconnected porous hydroxyapatite complex under functional loading conditions, DENTAL MATERIALS JOURNAL, 36(5), 647-653, 2017
    Link to Paper Search Results by DOI
  17. Enhanced Osseointegration of a Modified Titanium Implant with Bound Phospho-Threonine: A Preliminary In Vivo Study., J Funct Biomater, 8(2), E16-E16, 2017
    Link to Paper Search Results by DOI
  18. Intermittent administration of parathyroid hormone enhances primary stability of dental implants in a bone-reduced rabbit model, JOURNAL OF ORAL SCIENCE, 58(2), 241-246, 2016
    Link to Paper Search Results by DOI
  19. Tooth loss might not alter molecular pathogenesis in an aged transgenic Alzheimer's disease model mouse, GERODONTOLOGY, 33(3), 308-314, 2016
    Link to Paper Search Results by DOI
  20. Osseointegration aspects of placed implant in bone reconstruction with newly developed block-type interconnected porous calcium hydroxyapatite., Journal of applied oral science, 24(4), 325-331, 2016
  21. Radiographic Comparison of Periimplant Bone Resorption and Assessment of Survival Rates of 2 Implant Systems: A 10-Year Prospective Multicenter Study, IMPLANT DENTISTRY, 24(1), 77-82, 2015
    Link to Paper Search Results by DOI
  22. ★, Correlation between the Bone Density Recorded by a Computerized Implant Motor and by a Histomorphometric Analysis: A Preliminary In Vitro Study on Bovine Ribs, CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, 17, E35-E44, 2015
    Link to Paper Search Results by DOI
  23. The Effect of Superstructures Connected to Implants with Different Surface Properties on the Surrounding Bone, J Funct Biomater, 623-633, 2015
  24. Influence of implant surface topography on primary stability in a standardized osteoporosis rabbit model study., Journal of functional biomaterial, 6(1), 143-152, 2015
  25. Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study, JOURNAL OF FUNCTIONAL BIOMATERIALS, 6(1), 143-152, 201503
    Link to Paper Search Results by DOI
  26. The Effect of Superstructures Connected to Implants with Different Surface Properties on the Surrounding Bone, JOURNAL OF FUNCTIONAL BIOMATERIALS, 6(3), 623-633, 201509
    Link to Paper Search Results by DOI
  27. The influence of fixation in formalin on the measurement of stability of implants using resonance frequency analysis and Periotest M (R): A study in a dog, BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 52(1), 29-33, 2014
    Link to Paper Search Results by DOI
  28. Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration: an animal study., Dental Materials Journal, 33(3), 179-186, 20140301
  29. Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration: An animal study, DENTAL MATERIALS JOURNAL, 33(2), 179-186, 2014
    Link to Paper Search Results by DOI
  30. Inorganic Polyphosphate Suppresses Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase (iNOS) Expression in Macrophages, PLOS ONE, 8(9), 2013
    Link to Paper Search Results by DOI
  31. Polyphosphate-Mediated Inhibition of Tartrate-Resistant Acid Phosphatase and Suppression of Bone Resorption of Osteoclasts, PLOS ONE, 8(11), 2013
    Link to Paper Search Results by DOI
  32. Influence of formalin fixation on the implant stability quotient and mechanical characteristics of bone, BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 51(6), 550-554, 2013
    Link to Paper Search Results by DOI
  33. Correlation between the Bone Density Recorded by a Computerized Implant Motor and by a Histomorphometric Analysis: A Preliminary In Vitro Study on Bovine Ribs., 20130701
  34. Development of inorganic polyphosphate-adsorbed interconnected porous hydroxyapatite, 5(4), 417-419, 20131001
  35. Development of Implant/Interconnected Porous Hydroxyapatite Complex as New Concept Graft Material, PLOS ONE, 7(11), 2012
    Link to Paper Search Results by DOI
  36. Comparative evaluation of bone regeneration using spherical and irregularly shaped granules of interconnected porous hydroxylapatite. A beagle dog study., J Prosthodont Res, 55(2), 104-9, 20110401
  37. Enhanced initial bone regeneration with inorganic polyphosphate-adsorbed hydroxyapatite, ACTA BIOMATERIALIA, 6(7), 2808-2815, 2010
    Link to Paper Search Results by DOI
  38. Effect of combined application of bFGF and inorganic polyphosphate on bioactivities of osteoblasts and initial bone regeneration, ACTA BIOMATERIALIA, 5(5), 1716-1724, 2009
    Link to Paper Search Results by DOI
  39. Bone formation ability of carbonate apatite-collagen scaffolds with different carbonate contents, DMJ, 28, 234-242, 20090101
  40. Initial bone regeneration around fenestrated implants in Beagle dogs using basic fibroblast growth factor-gelatin hydrogel complex with varying biodegradation rates., Journal of prosthdontic research, 53(1), 41-47, 2009
  41. Bone formation ability of carbonate apatite-collagen scaffolds with different carbonate contents, DENTAL MATERIALS JOURNAL, 28(2), 234-242, 2009
    Link to Paper Search Results by DOI
  42. Development of cell-hybrid artificial bone: Effect of osteogenic differentiation of bone marrow stromal stem cells on bone formation with newly developed interconnected porous calcium hydroxyapatite, DENTAL MATERIALS JOURNAL, 26(2), 162-169, 2007
    Link to Paper Search Results by DOI
  43. Development of new drug delivery system for implant bone augmentation using a basic fibroblast growth factor-gelatin hydrogel complex, DENTAL MATERIALS JOURNAL, 26(2), 170-177, 2007
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Evaluation of alkali treatment for porous titanium as bone reconstruction material, Kobatake R, Doi K, Makihara Y, Oki Y, Umehara H, Kubo T, Tsuga K, 98th General session & exhibition of the IADR, 2020/03/18, Without Invitation, English, IADR, Washington DC
  2. Aspect of apatite formation ability of alkali treated titanium membrane:, Umehara H, Doi K, Kobatake R, Kubo T, Tsuga K, 72n d annual meeting of Japanese society for dental materials and devices, 2019/10/06, Without Invitation, Japanese, Japanese society for dental materials and devices, Sapporo
  3. Investigation of surface topography and apatite formation ability on the alkali treated titanium membrane, Umehara H, Kubo T, Doi K, Kobatake R, Oki Y, Tsuga K, The 38th annual meeting of the Chugoku/Shikoku branch of the Japanese society o f oral implantology, 2018/11/17, Without Invitation, Japanese, Japanese society o f oral implantology, Hiroshima
  4. Biology of non-absorbable artificial bone for implant therapy, Doi K, The 61 Autumun meeting of Japanese society periodontology, 2018/10/26, With Invitation, Japanese, Japanese society of periodontology, Osaka, other
  5. Osseointegration aspect of implants placed in bone reconstructed site with novel porous titanium, Kobatake R, Doi K, Oki Y, Yokoi M, Makihara Y, Umehara H, Kubo T, Tsuga K, 27th annual scientific meeting of European association for Osseointegration, 2018/10/12, Without Invitation, English, EAO, Viena
  6. Intermittent parathyroid hormone administration enhances implant stability in osteoporosis model, Oki Y, Doi K, Makihara Y, Kubo T, Tsuga K, 27th annual scientific meeting of European association for osseointegration, 2018/10/12, Without Invitation, English
  7. Investigation of material property and bioactivity of novel developed bioactive titanium membrane, Umehara H, Doi K, Kobatake R, Oki Y, Kubo T, Tsuga K, Academy of Osseointegration, 2018/10/10, Without Invitation, English, AAO, Seoul
  8. Surface decontamination of titanium thin membrane by UV LED irradiation, Makihara Y, Doi K, Umehara H, Yasuda K, Abe Y, Tsuga K, The 11th Congress of the Asian Academy of Osseointegration, 2018/10/10, Without Invitation, English, AAO, Seoul
  9. Investigation of material property and bioactivity of novel developed bioactive titanium membrane, Doi k, Kubo T, Kobatake R, Oki Y, Umehara H, Makihara Y, Tsuga K, The 47th Annual Meeting of the Japanese Society of Oral Implantology, 2018/09/15, Without Invitation, Japanese, Japanese Society of Oral Implantology, Osaka
  10. Physical and biological characteristics of a novel porous titanium block for bone reconstruction, Kobatake R, Doi K, Oki Y, Makihara Y, Kubo T, Tsuga K, 96th General session & exhibition of the IADR, 2018/07/25, Without Invitation, English, IADR, London (UK)
  11. Histological aspects of an implant in the bone reconstructed with porous titanium, Kobatake R, Kubo T, Doi K, Oki Y, Makihara Y, Tsuga K, The 37th annual meeting of the Chugoku-Shikoku branch of the Japanese society of oral implantology, 2017/11/18, Without Invitation, Japanese, Japanese society of oral implantology, Tokushima, experimental
  12. Influence of surface modification on structure and mechanical strength of titanium thin membrane, Umehara H, Kubo T, Doi K, Kobatake R, Oki Y, Tsuga K, The 37th annual meeting of the Chugoku-Shikoku branch of the Japanese society of oral implantology, 2017/11/18, Without Invitation, Japanese, The Japanese society of oral implantology, Tokushima
  13. Effect of polymerization temperature on the properties of autopolymerizing resin, Morita K, Tsuka H, Kobatake R, Doi K, Tsuga K, The 70nd General Session of the Japanese Society for Dental Materials and Devices, 2017/10/15, Without Invitation, Japanese, The Japanese Society for Dental Materials and Devices, Niigata
  14. Novel development of bioactive porous hydroxyapatite, Doi K, Abe Y, Okazaki Y, Kobatake R, Morita K, Tsuka H, Tsuga K, The 70th of academic meeting of the Japanese society for dental materials and devices, 2017/10/15, Without Invitation, Japanese, The Japanese society for dental materials and devices, Niigata
  15. Evaluation of laser pretreatment on bonding durability of adhesive resin cements to polyetheretherketone(PEEK), Tsuka H, Morita K, Doi K, Kobatake R, Abekura H, Tsuga K, The 70th Scientific Meeting of the Japan Society for Dental Materials and Devices, 2017/10/14, Without Invitation, Japanese, The Japan Society for Dental Materials and Devices, Niigata, experimental
  16. Bioactive surface modification of titanium membrane, Oki Y,Doi K, Kobatake R, Yokoi, Kato K, Kubo T, Tsuga T, 26th Annual scientific meeting of the European association for osseointegration, 2017/10/05, Without Invitation, English, European association for osseointegration, Madrid
  17. Novel development of three demensional porous titanium, Doi Kazuya, Hiroshima University New Technology Presentation Meetings, 2017/08/21, With Invitation, Japanese, HIroshima university, Hiroshima, published
  18. Novel porous titanium biomaterial with three dimensional structure, Doi K, Bio tech 2017 Academic forum, 2017/06/30, With Invitation, Japanese, Reede expo. Japan, Tokyo
  19. Effect of intermittent parathyroid hormone administration on osseointegration aspects in rabbit osteoporosis model, Kazuya Doi, Yoshifumi Oki, Hiroshi Oue, Yusuke Makihara, Katsunori Koretake, Takayasu Kubo, Kazuhiro Tsuga, European Association of Osseoinntegration 24th annual scientific meeting, 2015/09/24, Without Invitation, English, Stockholm
  20. Evaluation of implant stability in implant-interconnected pours hydroxyapatite complex, Kajihara S, Doi K, Kubo T, Oue H, Makihara Y, Morita K, Kato K, Akagawa Y., The 23th European Assosiation for Osseointegration, 2014/09/24, Without Invitation, English, European Assosiation for Osseointegration, Rome
  21. Effect of intermittent PTH administration on primary stability in osteoporosis rabbit model, Oue H, Doi K, Oki Y, Makihara Y, Kajihara S, Koretake K, Kubo T, Akagawa Y, Tsuga T., The 23th European Assosiation for Osseointegration, 2014/09/24, Without Invitation, English, European Assosiation for Osseointegration, Rome
  22. Effect of intermittent parathyroid hormone administration on primary stability in rabbit osteoporosis model, Asian Academy of Osseointegration; 9th meeting (Sapporo, Japan), 2014, 2014/07/04, Without Invitation, English
  23. Evaluation of implant stability in novel implant/interconnected porous calucium hydroxyapatite complex, Makihara Y, Doi k, Kubo T, Oue H, Kajihara S, Morita K, Akagawa Y, Tsuga K., Asian Academy of Osseointegration; 9th meeting (Sapporo, Japan), 2014, 2014/07/04, Without Invitation, English, Asian Academy of Osseointegration, Sapporo

Awards

  1. 2009, The 13th Meeting of the International College of Prosthodontists, International College of Prosthodontists

Patented

  1. Patent, 4215595

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  2. Adaptable and Seamless Technology transfer Program through targetdriven R&D(A-STEP), 2021/05/01, 2022/03/31
  3. KAKENHI, 2012, 2014
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  4. KAKENHI, 2012, 2014
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  5. KAKENHI, Development of diagnosis system of immediate loading dental implant based on bone dinamics, 2011, 2013
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  6. KAKENHI, Development of novel nucleic acid medicine artificial bone using bioprocessed NF-kB decoy, 2011, 2013
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  7. KAKENHI, Development of poly(P) adsorbed Electrical polarized hydroxyapatite artificial bone., 2010, 2011
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  8. KAKENHI, New development of bFGF/ poly-phosphate adsorbed artificial bone, 2009, 2011
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  9. KAKENHI, Bone regeneration using the Intelligent artificial bone, 2008, 2009
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  10. KAKENHI, Establish of bone improve therapy using inteligent artificial bone, 2015, 2017
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  11. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2018, 2020

Social Activities

History as Committee Members

  1. Representative of JOI(Blanch-chushikoku), 2018, 2018, Society of Japanese Oral implantoloy