Kazuyoshi Ukena

Last Updated :2021/07/08

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Professor
E-mail
ukenahiroshima-u.ac.jp
Self-introduction
I want to identify new regulators in the brain and elucidate the molecular mechanisms in the brain of biological function, especially instinctive behavior such as appetite and regulation of energy metabolism. I am aiming for new discoveries in the field of neurometabolic regulation.

Basic Information

Academic Degrees

  • Doctor of Philosophy, Hiroshima University
  • Master of Science, Hiroshima University

Educational Activity

  • 【Bachelor Degree Program】School of Integrated Arts and Sciences : Department of Integrated Arts and Sciences
  • 【Master's Program】Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Life and Environmental Sciences
  • 【Master's Program】Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biomedical Science
  • 【Doctoral Program】Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Life and Environmental Sciences
  • 【Doctoral Program】Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biomedical Science

Research Fields

  • Medicine,dentistry, and pharmacy;Basic medicine;Environmental physiology (including physical medicine and nutritional physiology)
  • Biology;Basic biology;Animal physiology / Animal behavior
  • Biology;Basic biology;Morphology / Structure

Research Keywords

  • Neurometabolism, Neuroendocrinology, Zoology

Educational Activity

Course in Charge

  1. 2021, Liberal Arts Education Program1, 4Term, Stress in the biological context
  2. 2021, Liberal Arts Education Program1, 2Term, Experimental Methods and Laboratory Work in Science A
  3. 2021, Liberal Arts Education Program1, 3Term, Experimental Methods and Laboratory Work in Biology I
  4. 2021, Liberal Arts Education Program1, 4Term, Experimental Methods and Laboratory Work in Biology II
  5. 2021, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  6. 2021, Undergraduate Education, 2Term, Natural Sciences of Life and Environment
  7. 2021, Undergraduate Education, 2Term, Introduction to Life Sciences
  8. 2021, Undergraduate Education, 2Term, Cell Biology
  9. 2021, Undergraduate Education, 1Term, Brain Function
  10. 2021, Undergraduate Education, First Semester, Fundamental Laboratory Work in Biology
  11. 2021, Undergraduate Education, First Semester, Fundamental Methodology in Biology
  12. 2021, Undergraduate Education, 1Term, Fundamentals of Life Science
  13. 2021, Graduate Education (Master's Program) , 1Term, Exercises in Life and Environmental Sciences A
  14. 2021, Graduate Education (Master's Program) , 2Term, Exercises in Life and Environmental Sciences A
  15. 2021, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Life and Environmental Sciences
  16. 2021, Graduate Education (Master's Program) , 3Term, Exercises in Life and Environmental Sciences B
  17. 2021, Graduate Education (Master's Program) , 4Term, Exercises in Life and Environmental Sciences B
  18. 2021, Graduate Education (Master's Program) , 1Term, Introduction to Integrated Arts and Sciences
  19. 2021, Graduate Education (Master's Program) , 3Term, Evolutional and environmental life science
  20. 2021, Graduate Education (Doctoral Program) , 2Term, Seminar in Integrated Arts and Scirnces II
  21. 2021, Graduate Education (Doctoral Program) , 4Term, Exercises in Integrated Life Sciences
  22. 2021, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  23. 2021, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  24. 2021, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
  25. 2021, Graduate Education (Master's Program) , 3Term, Introduction to Disease Models
  26. 2021, Graduate Education (Master's Program) , 1Term, Exercises in Biomedical Science A
  27. 2021, Graduate Education (Master's Program) , 2Term, Exercises in Biomedical Science A
  28. 2021, Graduate Education (Master's Program) , 3Term, Exercises in Biomedical Science B
  29. 2021, Graduate Education (Master's Program) , 4Term, Exercises in Biomedical Science B
  30. 2021, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
  31. 2021, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  32. 2021, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  33. 2021, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D
  34. 2021, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar E
  35. 2021, Graduate Education (Master's Program) , 4Term, Introduction to Genetics and Genomics

Research Activities

Academic Papers

  1. Effects of Overexpression of Neurosecretory Protein GL-Precursor Gene on Glucose Homeostasis and Insulin Sensitivity in Mice, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(9), 202105
  2. Adrenomedullin 2 and 5 activate the calcitonin receptor-like receptor (clr) - Receptor activity-modifying protein 3 (ramp3) receptor complex in Xenopus tropicalis, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 306, 20210515
  3. Effects of Irregular Feeding on the Daily Fluctuations in mRNA Expression of the Neurosecretory Protein GL and Neurosecretory Protein GM Genes in the Mouse Hypothalamus, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(4), 202102
  4. Effects of Chronic Intracerebroventricular Infusion of RFamide-Related Peptide-3 on Energy Metabolism in Male Mice, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(22), 202011
  5. Identification of neuropeptides in gastropod mollusks. - Classical and brand-new approaches –, IOP Conf. Ser.: Earth Environ. Sci., 012001, 202004
  6. Neurosecretory protein GL induces fat accumulation in mice, JOURNAL OF ENDOCRINOLOGY, 244(1), 1-12, 202001
  7. Neurosecretory Protein GL Induces Fat Accumulation in Chicks, FRONTIERS IN ENDOCRINOLOGY, 10, 20190619
  8. Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus, SCIENTIFIC REPORTS, 8, 20180115
  9. Effects of chronic intracerebroventricular infusion of neurosecretory protein GL on body mass and food and water intake in chicks, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 256, 37-42, 20180115
  10. Avian and murine neurosecretory protein GL participates in the regulation of feeding and energy metabolism, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 260, 164-170, 20180501
  11. Chronic subcutaneous infusion of neurosecretory protein GM increases body mass gain in chicks, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 265, 71-76, 20180901
  12. Neurosecretory Protein GL, a Hypothalamic Small Secretory Protein, Participates in Energy Homeostasis in Male Mice, ENDOCRINOLOGY, 158(5), 1120-1129, 201705
  13. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity, ELIFE, 6, 20170811
  14. The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24, BRITISH JOURNAL OF PHARMACOLOGY, 174(20), 3573-3607, 201710
  15. Peripheral Injection of Chicken Growth Hormone-Releasing Hormone Inhibits Feeding Behavior in Chicks, JOURNAL OF POULTRY SCIENCE, 53(1), 29-33, 201601
  16. Identification and localization of gonadotropin-inhibitory hormone (GnIH) orthologs in the hypothalamus of the red-eared slider turtle, Trachemys scripta elegans, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 227, 69-76, 20160201
  17. Synthesis of neurosecretory protein GM composed of 88 amino acid residues by native chemical ligation., Tetrahedron Lett., 57, 804-807, 2016
  18. Production and characterization of neurosecretory protein GM using Escherichia coli and Chinese Hamster Ovary cells, FEBS Open Bio, 5, 844-851, 2015
  19. Effects of neurotensin and LANT-6 on food intake in chicks, Am. J. Life Sci., 3, 17-23, 2015
  20. A unique mechanism of successful fertilization in a domestic bird, SCIENTIFIC REPORTS, 5, 20150109
  21. Central administration of chicken growth hormone-releasing hormone decreases food intake in chicks, PHYSIOLOGY & BEHAVIOR, 139, 195-201, 201502
  22. Microwave-assisted solid-phase peptide synthesis of neurosecretory protein GL composed of 80 amino acid residues, JOURNAL OF PEPTIDE SCIENCE, 21(6), 454-460, 201506
  23. 26Rfa/GPR103, JOURNAL OF MOLECULAR ENDOCRINOLOGY, 52(3), T119-T131, 201406
  24. Characterization of an avian histidine decarboxylase and localization of histaminergic neurons in the chicken brain, NEUROSCIENCE LETTERS, 578, 106-110, 20140822
  25. Identification of a cDNA encoding a novel small secretory protein, neurosecretory protein GL, in the chicken hypothalamic infundibulum, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 446(1), 298-303, 20140328
  26. Identification of Neurotensin and LANT-6 and Localization of mRNA Encoding Their Precursor in the Chicken Brain, ZOOLOGICAL SCIENCE, 31(6), 353-359, 201406
  27. Identification, localization and function of a novel neuropeptide, 26RFa, and its cognate receptor, GPR103, in the avian hypothalamus, GENERAL AND COMPARATIVE ENDOCRINOLOGY, 190, 42-46, 20130901
  28. Identification, Expression, and Physiological Functions of Siberian Hamster Gonadotropin-Inhibitory Hormone, ENDOCRINOLOGY, 153(1), 373-385, 201201
  29. Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 412(4), 673-677, 20110909
  30. Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae, PEPTIDES, 32(4), 670-676, 201104
  31. Identification and structure-activity relationship of an antimicrobial peptide of the palustrin-2 family isolated from the skin of the endangered frog Odorrana ishikawae, PEPTIDES, 32(10), 2052-2057, 201110
  32. Identification, Localisation and Functional Implication of 26RFa Orthologue Peptide in the Brain of Zebra Finch (Taeniopygia guttata), JOURNAL OF NEUROENDOCRINOLOGY, 23(9), 791-803, 201109
  33. Molecular evolution and functional characterization of the orexigenic peptide 26RFa and its receptor in vertebrates, CELL AND TISSUE RESEARCH, 343(3), 475-481, 201103
  34. Synchronised Expressions of LPXRFamide Peptide and its Receptor Genes: Seasonal, Diurnal and Circadian Changes During Spawning Period in Grass Puffer, JOURNAL OF NEUROENDOCRINOLOGY, 23(1), 39-51, 201101
  35. Identification, Localization, and Function of a Novel Avian Hypothalamic Neuropeptide, 26RFa, and Its Cognate Receptor, G Protein-Coupled Receptor-103, ENDOCRINOLOGY, 151(5), 2255-2264, 201005
  36. A New Key Neurohormone Controlling Reproduction, Gonadotrophin-Inhibitory Hormone in Birds: Discovery, Progress and Prospects, JOURNAL OF NEUROENDOCRINOLOGY, 21(4), 271-275, 200904
  37. Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: A new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid, CEREBELLUM, 7(1), 18-25, 200803
  38. The orexigenic effect of GnIH is mediated by central opioid receptors in chicks, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, 150(1), 21-25, 200805
  39. Unique Form and Osmoregulatory Function of a Neurohypophysial Hormone in a Urochordate, Endocrinology, 149(10), 5254-5261, 20081001
  40. Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance, JOURNAL OF ORNITHOLOGY, 148, S515-S520, 200712
  41. Discovery of gonadotropin-inhibitory hormone in a domesticated bird, its mode of action and functional significance., Journal of Ornithology, 515-520, 20070908
  42. Expression, localization and possible actions of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: A new insight into the biosynthesis, metabolism and multiple actions ofprogesterone as a neurosteroid., Cerebellum, 1-8, 20070302
  43. Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: neuroanatomy and functional biology, Journal of Ornithology, 521-526, 20070911
  44. Gonadotropin-inhibitory hormone in seasonally-breeding songbirds: neuroanatomy and functional biology, JOURNAL OF ORNITHOLOGY, 148, S521-S526, 200712
  45. The general and comparative biology of gonadotropin-inhibitory hormone (GnIH)., General and Comparative Endocrinology, 365-370, 20070801
  46. Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family., FEBS J., 273, 1731-1743, 20060401
  47. Gonadotropin-inhibitory hormone inhibits gonadal development and maintenance by decreasing gonadotropin synthesis and release in male quail., Endocrinology, 147, 1187-1194, 20060401
  48. Hypothalamic LPXRF-amide peptides in vertebrates: Identification, localization and hypophysiotropic activity (review)., Peptides, 27, 1121-1129, 20060401
  49. Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals., Proc. Natl. Acad. Sci. USA, 103, 2410-2415, 20060401
  50. Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals., J. Exp. Zool., 305, 807-814, 20060401
  51. Mode of action and functional significance of avian gonadotropin-inhibitory hormone (GnIH): a review., J. Exp. Zool., 305, 801-806, 20060401
  52. Neural interaction of gonadotropin-regulating hormone immunoreactive neurons and the suprachiasmatic nucleus with the paraventricular organ in the Japanese grass lizard (Takydromus tachydromoides)., Zool. Sci., 23, 277-287, 20060401
  53. Neurosteroid biosynthesis in the quail brain: a review., J. Exp. Zool., 305, 733-742, 20060401
  54. Novel fish hypothalamic neuropeptides stimulate the release of gonadotrophins and growth hormone from the pituitary of sockeye salmon, JOURNAL OF ENDOCRINOLOGY, 188(3), 417-423, 200603
  55. Structures and diverse functions of frog growth hormone-releasing peptide (fGRP) and its related peptides (fGRP-RPs): A review, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-COMPARATIVE EXPERIMENTAL BIOLOGY, 305A(9), 815-821, 20060901
  56. A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides: Structure, localization, and function, MASS SPECTROMETRY REVIEWS, 24(4), 469-486, 200507
  57. A novel G protein-coupled receptor for gonadotropin-inhibitory hormone in the Japanese quail (Coturnix japonica): identification, expression and binding activity, JOURNAL OF ENDOCRINOLOGY, 184(1), 257-266, 200501
  58. Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks., Brain Res., 1050, 94-100, 20050401
  59. Melatonin induces the expression of gonadotropin-inhibitory hormone in the avian brain., Proc. Natl. Acad. Sci. USA, 102, 3052-3057, 20050401
  60. 7 alpha-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(49), 17282-17287, 20041207
  61. Dendritic growth in response to environmental estrogens in the developing Purkinje cell in rats., Neurosci. Lett., 364, 114-118, 20040401
  62. Expression and distribution of octopus gonadotropin-releasing hormone in the central nervous system and peripheral organs of the octopus (Octopus vulgaris) by in situ hybridization and immunohistochemistry., J. Comp. Neurol., 477, 310-323, 20040401
  63. Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell., Neuroscience, 126, 325-334, 20040401
  64. Gonadotrophin inhibitory hormone depresses gonadotrophin alpha and follicle-stimulating hormone beta Subunit expression in the pituitary of the domestic chicken., J. Neuroendocrinol., 16, 999-1006, 20040401
  65. Gonadotropin-inhibitory hormone in Gambelユs white-crowned sparrow (Zonotrichia leucophrys gambelli): cDNA identification, transcript localization and functional effects in laboratory and field experiments., J. Endocrinol., 182, 33-42, 20040401
  66. Identification of 3b,5b-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain., Brain Res., 1007, 160-166, 20040401
  67. Organizing actions of neurosteroids in the Purkinje neuron, NEUROSCIENCE RESEARCH, 49(3), 273-279, 200407
  68. Photoperiodic response of serotonin- and galanin-immunoreactive neurons of the paraventricular organ and infundibular nucleus in Japanese quail, Coturnix cotumix japonica, ZOOLOGICAL SCIENCE, 21(5), 575-582, 200405
  69. A novel aspect of the cerebellum: biosynthesis of neurosteroids in the Purkinje cell, CEREBELLUM, 2(3), 215-222, 2003
  70. Biosynthesis and action of neurosteroids in the cerebellar Purkinje neuron., J. Steroid Biochem. Mol. Biol., 85, 311-321, 20030401
  71. Biosynthesis and biological actions of neurosteroids in the avian brain., Avian Poult. Biol. Rev., 14, 63-78, 20030401
  72. Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell., Endocrinology, 144, 4466-4477, 20030401
  73. Developmental changes in gonadotropin-inhibitory hormone in the quail hypothalamo-hypophysial system., J. Endocrinology, 178, 311-318, 20030401
  74. Distribution of a novel avian gonadotropin-inhibitory hormone in the quail brain., Cell Tissue Res., 312, 73-79, 20030401
  75. Gonadotropin-inhibitory peptide in song sparrows (Melospiza melodia) in different reproductive conditions, and in house sparrows (Passer domesticus) relative to chicken-Gonadotropin-releasing hormone., J. Neuroendocrinol., 15, 794-802, 20030401
  76. Neonatal expression of progesterone receptor isoforms in the cerebellar Purkinje cell in rats., Neurosci. Lett., 343, 163-166, 20030401
  77. Review: Biosynthesis and biological actions of neurosteroids in the avian brain., Avian Poultry Biol Reviews, 14, 63-78, 20030401
  78. Review:A novel aspect of the cerebellum: Biosynthesis of neurosteroids in the Purkinje cell., Cerebellum, 2, 215-222., 20030401
  79. Seasonal changes in neurosteroid concentrations in the amphibian brain and environmental factors regulating their changes, BRAIN RESEARCH, 959(2), 214-225, 20030110
  80. A novel amphibian hypothalamic neuropeptide: Isolation, localization, and biological activity, ENDOCRINOLOGY, 143(2), 411-419, 200202
  81. A novel rat hypothalamic RFamide-related peptide identified by immunoaffinity chromatography and mass spectrometry, FEBS LETTERS, 512(1-3), 255-258, 20020213
  82. Androgen biosynthesis in the quail brain, BRAIN RESEARCH, 948(1-2), 180-185, 20020906
  83. Dendritic spine formation in response to progesterone synthesized de novo in the developing Purkinje cell in rats., Neurosci. Lett., 322, 111-115, 20020401
  84. Identification of a cDNA encoding a novel amphibian growth hormone-releasing peptide and localization of its transcript., J. Endocrinol., 174, 395-402, 20020401
  85. Isolation and characterization of a GnRH-like peptide from Octopus vulgaris., Biochem. Biophys. Res. Commun., 291, 1187-1193, 20020401
  86. Novel fish hypothalamic neuropeptide - Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide, EUROPEAN JOURNAL OF BIOCHEMISTRY, 269(24), 6000-6008, 200212
  87. A novel hypothalamic neuropeptide: Gonadotropin-inhibitory hormone., Internat. J. Mol. Med., 8, 400-405, 20010401
  88. Activity and localization of 3 beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4)-isomerase in the zebrafish central nervous system, JOURNAL OF COMPARATIVE NEUROLOGY, 439(3), 291-305, 20011022
  89. Characterization of a cDNA encoding a novel avian hypothalamic neuropeptide exerting an inhibitory effect on gonadotropin release., Biochem. J., 354, 379-385, 20010401
  90. Developmental changes in galanin in lumbosacral sympathetic ganglionic neurons innervating the avian uterine oviduct and galanin induction by sex steroids., J. Endocrinol., 170, 357-368, 20010401
  91. Developmental changes in progesterone biosynthesis and metabolism in the quail brain., Brain Res., 898, 190-194, 20010401
  92. Distribution of novel RFamide-related peptide-like immunoreactivity in the mouse central nervous system., Neurosci. Lett., 300, 153-156, 20010401
  93. Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis., J. Neurosci., 21, 6221-6232, 20010401
  94. A novel avian hypothalamic peptide inhibiting gonadotropin release, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 275(2), 661-667, 20000828
  95. Existence of galanin in lumbosacral sympathetic ganglionic neurons that project to the quail uterine oviduct., Endocrinology, 141, 4402-4412, 20000401
  96. Neurosteroid biosynthesis in the avian brain., 4th International Symposium on Recent Trends in Life Sciences, 25, 20000401
  97. Neurosteroidogenesis in the avian brain., VII International Symposium on Avian Endocrinology, 20000401
  98. Novel brain function: biosynthesis and actions of neurosteroids in neurons, NEUROSCIENCE RESEARCH, 36(4), 261-273, 200004
  99. Production of progesterone and expression of progesterone receptor in the brain of the non-breeding and brooding ring dove., VII International Symposium on Avian Endocrinology, 20000401
  100. Review:Novel brain function : biosynthesis and actions of neurosteroids in neurons, Neurosci. Res., 36, 261-273, 20000401
  101. Comparison of precursor structures of the GGNG peptides derived from the earthworm Eisenia foetida and the leech Hirudo nipponia., Biosci. Biotechnol. Biochem., 63, 443-445, 19990401
  102. Expression and activity of 3b-hydroxysteroid dehydrogenase/D5-D4-isomerase in the rat Purkinje neuron during neonatal life., Endocrinology, 140, 805-813, 19990401
  103. Localization of the leech excitatory peptide, a member of the GGNG peptides, in the central nervous system of a leech (Whitmania pigra) by immunohistochemistry and in situ hybridization, Cell Tissue Res., 297, 155-162, 19990401
  104. Neurosteroids in the cerebellar purkinje neuron and their actions., Int. J. Mol. Med., 4, 49-56, 19990401
  105. Possible functions of oxytocin/vasopressin-superfamily peptides in annelids with special reference to reproduction and osmoregulation, Journal of Experimental Zoology, 284, 401-406, 19990401
  106. Pregnenolone, pregnenolone sulfate, and cytochrome P450 side-chain cleavage enzyme in the amphibian brain and their seasonal changes., Endocrinology, 140, 1936-1944, 19990401
  107. Neurosteroids in the cerebellar Purkinje neuron and their actions. (Review)., International Journal of Molecular Medicine, 4, 49-56, 19990401
  108. Review:Neurosteroids in vertebrate brains., Comparative Biochemistry and Physiology Part C, 124, 121-129, 19990401
  109. Cytochrome P450 side-chain cleavage enzyme in the cerebellar Purkinje neuron and its neonatal change in rats., Endocrinology, 139, 137-147, 19980401
  110. Developmental changes in galanin receptors in the quail oviduct and the effect of ovarian sex steroids on galanin receptor induction., Endocrinology, 139, 4230-4236, 19980401
  111. Immunohistochemical localization of annetocin, an earthworm oxytocin-related peptide, and identification and ultrastructural characteristics of the annetocin-secretory cells in the oligochaete earthworm Eisenia foetida., Zoological Science, 15, 381-388, 19980401
  112. Biosynthesis and function of neurosteroids in the rat cerebellar Purkinje neuron., Evolutionary Aspects of Chemical Messengers and Their Receptors, 48, 19970401
  113. Characterization of binding of the annelidan myoactive peptides, GGNG peptides, to tissues of the earthworm, Eisenia foetida, Journal of Experimental Zoology, 279, 562-570, 19970401
  114. Immunochemical demostration of Eisenia tetradecapeptide, a bioactive peptide isolated from the gut of the earthworm Eisenia foetida, in tissues of the earthworm., Cell Tissue Res., 288, 567-573, 19970401
  115. The leech excitatory peptide, a member of the GGNG peptide family : isolation and comparison with the earthworm GGNG peptides., FEBS Lett, 410, 437-442, 19970401
  116. An excitatory tetradecapeptide isolated from the gut of the earthworm, Eisenia foetida, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., 236-237, 19960401
  117. Annetocin, an annelid oxytocin-related peptide, induces egg-laying behavior in the earthworm, Eisenia foetida., J. Exp. Zool., 276, 151-156, 19960401
  118. Annetocin, an annelid oxytocin-related peptide, induces egg-laying behavior of the earthworm, Eisenia foetida, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., 234-235, 19960401
  119. Bioactivity and cDNA cloning of GGNG peptides isolated from the earthworms and the leech, Proc. 3rd Congr. Asia-Oceania Soc. Comp. Endocrinol., 209-210, 19960401
  120. Gene structures of the GGNG-peptides derived from Annelida and the gene products, Peptide Chem, 1995, 321-324, 19960401
  121. Inhibitory pentapeptides isolated from the gut of the earthworm, Eisenia foetida., Comp. Biochem. Physiol. A., 114, 245-249, 19960401
  122. A novel gut tetradecapeptide isolated from the earthworm, Eisenia foetida., Peptides, 16, 995-999, 19950401
  123. Bioactive peptides of annelids are closely related to those of molluscs, Acta Biologica Hungarica, 46(2-4), 453-456, 19950401
  124. Effects of annetocin, an oxytocin-related peptide isolated from the earthworm Eisenia foetida, and some putative neurotransmitters on gut motility of the earthworm., J. Exp. Zool., 272, 184-193, 19950401
  125. Neurosteroid biosynthesis in vertebrate brains., Comparative Biochem. Physiol. Part C, 124, 121-129, 19950601
  126. The GGNG peptides : novel myoactive peptides isolated from the gut and the whole body of the earthworms., Biochem. Biophys. Res. Commun., 216, 1072-1078, 19950401
  127. Annetocin : an oxytocin-related peptide isolated from the earthworm, Eisenia foetida., Biochem. Biophys. Res. Commun., 198, 393-399, 19940401

Publications such as books

  1. 2015, Handbook of Hormones. Comparative Endocrinology for Basic and Clinical Research, Pyroglutamylated RFamide Peptide, Elsevier, 2015, Scholarly Book, Joint work, Ukena K, Tsutsui K, 16-17
  2. 2007/10, Study on processing mechanisms of novel identified neuropeptides. , 2007, 10, Report, Single work
  3. 2004, A novel amphibian neurosteroid stimulating locomotor activity. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  4. 2004, Classical and novel neurosteroids in vertebrate brains. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  5. 2004, Comparative aspects of novel hypothalamic LPXRF-amide peptides in the vertebrate brain: Structure, localization and function. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  6. 2004, Effects of RF-amide peptides on the release of TSH from the bullfrog pituitary. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  7. 2004, Identification and localization of a novel lamprey hypothalamic neuropeptide of the RF-amide peptide family. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  8. 2004, Novel avian neurosteroid: Identification of 7alpha-hydroxypregnenolone in the quail brain. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  9. 2004, Synapse formation in response to estrogen synthesized de novo in the developing Purkinje cell. , Trends in Comparative Endocrinology= AOSCE, 2004, Scholarly Book, Joint work
  10. 2003, Biosynthesis and action of neurosteroids in the cerebellar Purkinje neuron. , Hormonal Steroids and Hormones and Cancer, 2003, Scholarly Book, Cocompilation
  11. 2002, Novel cerebellar function: neurosteroids in the Purkinje neuron and their genomic and nongenomic actions. , Neuroplasticity= development= and steroid hormone action= CRC press, 2002, Scholarly Book, Joint work
  12. 2001, A novel avian hypothalamic peptide. , Recent Advances in Comparative Endocrinology= Academia Sinica, 2001, Scholarly Book, Joint work
  13. 2001, A novel hypothalamic peptide inhibiting gonadotropin release. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001, Scholarly Book, Joint work
  14. 2001, Isolation and characterization of a GnRH-like peptide from Octopus Vulgaris. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001, Scholarly Book, Joint work
  15. 2001, Sympathetic ganglionic galanin neurons evoke avian oviposition by innervating the uterine oviduct: a novel neuronal mechanism of avian oviposition. , Perspective in Comparative Endocrinology: Unity and Diversity= Medimond Inc., 2001, Scholarly Book, Joint work
  16. 2000, Neuronal neurosteroidogenesis in the cerebellum. , Molecular Steroidogenesis= Universal Academy Press, 2000, Scholarly Book, Joint work
  17. 1997, Neurosteroids in the avian brain. , Frontiers in environmental and metabolic endocrinology= Burdwan Press, 1997, Scholarly Book, Joint work
  18. 1997, P450scc activity in the brain. , Perspectives in avian endocrinology= Journal of Endocrinology Ltd., 1997, Scholarly Book, Joint work
  19. 1996, Gene structures of the GGNG-peptides derived from annelida and the gene products. , Peptide Chemistry 1995= Protein Research Foundation, 1996, Scholarly Book, Joint work

Social Activities

Other Social Contributions

  1. Research, Recently discovered brain chemical NPGL controls appetite and body fat composition–beneficial for our ancestors; potential cause of obesity pandemic, 2017/08/21
  2. Research, New appetite control mechanism found in brain - reason food looks even better when dieting, 2017/05/01

History as Peer Reviews of Academic Papers

  1. 2020, Front. Neuroendcrinol., Others
  2. 2020, Front. Physiol., Others
  3. 2020, Zool. Sci., Others
  4. 2020, Brain Res. Bull., Others
  5. 2020, Zool. Sci., Others
  6. 2020, J. Int. Neurosci., Others
  7. 2020, Front. Physiol., Others
  8. 2020, Frontiers in Pharmacology, Editor
  9. 2020, Frontiers in Physiology, Editor