AKIHISA MIYAGAWA

Last Updated :2025/07/30

Affiliations, Positions
Graduate School of Advanced Science and Engineering, Assistant Professor
E-mail
miyagawaakihiroshima-u.ac.jp

Basic Information

Research Fields

  • Chemistry;Applied chemistry;Analytical chemistry

Research Keywords

  • Trace analysis Physical field Particle trapping Zeta potential Ultrasound Molecular crowding

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 3Term, Experimental Methods and Laboratory Work in Chemistry I
  2. 2025, Liberal Arts Education Program1, 4Term, Experimental Methods and Laboratory Work in Chemistry II
  3. 2025, Undergraduate Education, First Semester, Special Study for Graduation
  4. 2025, Undergraduate Education, Second Semester, Special Study for Graduation
  5. 2025, Undergraduate Education, First Semester, Chemical Experiments I
  6. 2025, Undergraduate Education, Second Semester, Chemical Experiments II

Research Activities

Academic Papers

  1. Detection Scheme of Arginine as Aptamer Target Based on Particle Dissociation in Coupled Acoustic-Gravitational Field, Analytical Sciences, 41, 1407-1412, 202507
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  2. Intraparticle Diffusion of Proteins in Diol Group-Functionalized Porous Silica Particle Revealed by Fluorescence Correlation Spectroscopy, Analytical Sciences, 2025
  3. Biosensing Strategies Based on Particle Behavior, Chemosensors, 11, 172, 2023
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  4. Particle Manipulation with External Field; from Recent Advancement to Perspectives, Analytical Sciences, 37, 69-78, 2021
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  5. Amplification sensing manipulated by a sumanene-based supramolecular polymer as a dynamic allosteric effector, Scientific Report, 14, 12534, 2024
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  6. Probing the interaction between biomolecules under sub-zero temperature conditions by electrophoresis in ice grain boundaries., Analytical Chimica Acta, 1311, 342713, 2024
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  7. Acid dissociation constant of bis(2-ethylhexyl) hydrogen phosphate impregnated in a polymer layer coated on silica microparticles, The Bulletin of Chemistry Society of Japan, 95, 566-568, 2022
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  8. Zeptomole detection of DNA based on microparticle dissociation from a glass plate in a combined acoustic-gravitational field., Talanta, 238, 123042, 2022
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  9. Acid dissociation under hydrostatic pressure: structural implications for volumetric parameters, Journal of Molecular Liquids, 328, 115512, 2021
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  10. Space Size Dependent Transformation of Tetraphenylethylene Carboxylate Aggregates by Ice-Confinement, The Journal of Physical Chemistry B, 124, 2209-2217, 2020
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  11. Growth and Morphology of Liquid Phase in Frozen Aqueous NaCl Probed by Voltammetry and Simulations, ChemPhysChem, 19, 3150-3157, 2018
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  12. Multiple MicroRNA Quantification Based on Acoustic Levitation of Single Microspheres after One-Pot Sandwich Interparticle Hybridizations, Analytical Chemistry, 90, 13729-13735, 2018
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  13. Detection of Microsphere Surface Reaction Using Acoustic-Gravity Field, Proceeding of Acoustofluidics 2017, 2017, 66-66, 2017
  14. ★, Zeptomole Detection Scheme Based on Levitation Coordinate Measurements of a Single Microparticle in a Coupled Acoustic-Gravitational Field, Analytical Chemistry, 90, 2310-2316, 2018
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  15. Zeptomole Biosensing of DNA with Flexible Selectivity Based on Acoustic Levitation of a Single Microsphere Binding Gold Nanoparticles by Hybridization, ACS Sensors, 3, 1870-1875, 2018
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  16. Aptamer-Based Sensing of Small Organic Molecules by Measuring Levitation Coordinate of Single Microsphere in combined Acoustic-Gravitational Field, ACS Omega, 5, 3542-3549, 2020
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  17. ★, Multiphase Behavior of Tetraphenylethylene Derivatives with Different Polarities at High Pressures, The Journal of Physical Chemistry B, 124, 7263-7271, 2020
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  18. Hydrostatic-Pressure-Controlled Molecular Recognition: A Steroid Sensing Case Using Modified Cyclodextrin, ChemPhotoChem, 5, 118-122, 2021
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  19. Freeze Control of Nanoparticle Aggregation and Exploration as Surface Enhanced Raman Scattering (SERS) Platform, ChemNanoChem, 7, 434-438, 2021
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  20. Acoustic Sensing Based on Density Shift of Microspheres by Surface Binding of Gold nanoparticles, Analytical Sciences, 33, 939-944, 2017
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  21. Hydrostatic Pressure-Induced Spectral Variation of Reichardt's Dye: A Polarity/Pressure Dual Indicator, ACS Omega, 5, 897-903, 2020
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  22. Kinetic Analysis of the Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle by Confocal Fluorescence Microspectroscopy, Langmuir, 37, 12697-12704, 2021
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  23. Hydrostatic Pressure-Regulated Cellular Calcium Responses, Langmuir, 37, 820-826, 2021
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  24. Effect of Molecular Crowding on Complexation of Metal Ions and 8-Quinolinol-5-Sulfonic Acid., The Journal of Physical Chemistry B, 125, 9853-9859, 2021
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  25. Kinetically revealed transfer mechanism of europium (III) in tributyl phosphate microdroplet/NaNO3 aqueous solution system by fluorescence microspectroscopy, Journal of Molecular Liquids, 352, 118757, 2022
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  26. ★, Direct Quantification of Proteins Modified on a Polystyrene Microparticle Surface Based on  Potential Change, Analytical Chemistry, 94, 6304-6310, 2022
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  27. Kinetics and mechanism of Eu(III) transfer in tributyl phosphate microdroplet/HNO3 aqueous solution system revealed by fluorescence microspectroscopy, Analytical Sciences, 38, 955-961, 2022
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  28. Acid Dissociation Behavior of 8-Hydroxyquinoline-5-Sulfonic Acid in Molecular Crowding Environment Modeled Using Polyethylene Glycol., Journal of Molecular Liquids, 360, 119526, 2022
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  29. Distribution Behavior of Single-Stranded DNA Molecules in an Amino-Group-Functionalized Silica Microparticle, Langmuir, 38, 8462-8468, 2022
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  30. J-aggregation of 5, 10, 15, 20-tetraphenyl-21H, 23H-porphinetetrasulfonic acid in a molecular crowding environment simulated using dextran, Analytical Sciences, 38, 1505-1512, 2022
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  31. Semi-quantification of the binding constant based on bond breaking in a combined acoustic–gravitational field, Analyst, 147, 4735-4738, 2022
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  32. Two-Step Modification of Proteins onto Microparticle Surface Using DMT-MM Condensation Agent, The Bulletin of Chemistry Society of Japan, 96, 95-97, 2023
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  33. Thermodynamic complexation mechanism of zinc ion with 8-hydroxyquinoline-5-sulfonic acid in molecular crowding environment., Journal of Molecular Liquids, 372, 1121181, 2023
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  34. Kinetic Mass Transfer Behavior of Eu(III) in Nitrilotriacetamide-Impregnated Polymer-Coated Silica Particle., The Bulletin of Chemistry Society of Japan, 96, 671-676, 2023
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  35. Effects of Single-Stranded DNA Base Number and Duplex DNA Formation on Intraparticle Diffusion Behavior, The Bulletin of Chemistry Society of Japan, 96, 989-994, 2023
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  36. Pore Size Dependence of Mass Transfer of Zinc Myoglobin in a Single Mesoporous Silica Particle, Langmuir, 39, 11329-11336, 2023
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  37. Investigating hydrophobic environment in alkyl-group-functionalized silica particle with various chain lengths using absorption microspectroscopy, Analytical Sciences, 40, 93-99, 2024
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  38. Competitive Distribution of Europium and Samarium Based on Reaction Rate-Limiting Process in Nitrilotriacetamide Extractant-Impregnated Polymer-Coated Silica Particles, The Bulletin of Chemistry Society of Japan, 96, 1019-1025, 2023
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  39. Biosensing of DNA through difference in interaction between microparticle and glass plate based on particle dissociation in a coupled acoustic-gravitational field, Talanta, 273, 125925, 2024
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  40. Kinetic analysis of mass transfer of Eu(III) in extractant-impregnated polymer-layered silica particle in multiple-ion distribution system, Analytical Sciences, 40, 347-352, 2024
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  41. Molecular crowding effect in Hantzch pyridine synthesis in polyethylene glycol aqueous solution, Physical Chemistry Chemical Physics, 26, 5615-5620, 2024
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  42. Kinetic detection of hydrogen peroxide in single horseradish peroxidase-concentrated silica particle using confocal fluorescence microspectroscopic measurement, Talanta, 273, 125925, 2024
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  43. Evolution of myoglobin diffusion mechanisms: exploring pore and surface diffusion in a single silica particle., Analytical Sciences, 40, 1545-1551, 2024
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  44. Dynamic Interfacial Tension Measurement for the Kinetic Study of Eu(III) Extraction in the NaNO3/Tributyl Phosphate System Based on an Increase in Interfacial Tension., Langmuir, 40, 8645-8653, 2024
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  45. Diffusion behavior of rhodamine 6G in single octadecylsilyl-functionalized silica particle revealed by fluorescence correlation spectroscopy., Analytical Sciences, 40, 1561-1567, 2024
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  46. Chelate extraction of metal ions in aqueous/chloroform system based on molecular crowding environment., The Bulletin of Chemistry Society of Japan, 97, uoae064, 2024
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  47. Effect of Organic Solvent on the Mass Transfer Mechanism of Coumarin 102 in a Single Octadecylsilyl Silica Gel/Organic Solvent-Water System by Laser Trapping and Fluorescence Microspectroscopy, Langmuir, 40, 14303-14310, 2024
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  48. DNA sensing based on aggregation of Janus particles using dynamic light scattering, Analytical Chimica Acta, 1318, 342933, 2024
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  49. Orientation of Antibody Modified and Reacted on Carboxy-Functionalized Polystyrene Particle Revealed by Zeta Potential Measurement, Analytical Chemistry, 96, 14265-14273, 2024
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  50. Temperature Dependence of Intraparticle Diffusion of Coumarin in Single Octadecylsilyl-Functionalized Silica Particle Revealed by Fluorescence Microspectroscopy., The Bulletin of Chemistry Society of Japan, 97, uoae127, 2024
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  51. Intraparticle Diffusion Behavior of Rhodamine 6G in Single Silica Particle Revealed by Fluorescence Correlation Spectroscopy., Langmuir, 41, 4076-4083, 2025
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  52. Protein Adsorption on Carboxy-Functionalized Microparticles Revealed by Zeta Potential and Absorption Spectroscopy Measurements, Analytical Chemistry, 96, 759-765, 2023
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  53. Eu(III) transfer in single N,N,N,N-tetraoctyldiglycolamide-impregnated polymer-coated silica particle using fluorescence microspectroscopy: transfer mechanism and effect of polymer crosslinking degreeParticle., Analytical Sciences, 39, 1929-1936, 2023
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  54. Coumarin-Derivatives Diffusion in Single Octadecylsilyl-Functionalized Silica Particle Observed by Fluorescence Correlation Spectroscopy, The Bulletin of Chemistry Society of Japan, 98, uoaf038, 202505