YUICHI MINE

Last Updated :2025/02/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Associate Professor or Lecturer

Basic Information

Major Professional Backgrounds

  • 2018/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Lecturer
  • 2018/04/01, 2020/03/31, Hiroshima University, Translational Research Center, Department Head
  • 2017/04/01, 2018/03/31, Kyushu University, School of Medical Sciences, Lecturer
  • 2017/06/14, 2017/07/14, National Center for Advancing Translational Sciences, Division of Pre-Clinical Innovation, Special Volunteer
  • 2015/10/01, 2017/03/31, Kyushu University, School of Medical Sciences, Assistant Professor
  • 2014/04/01, 2015/09/30, Japan Science and Technology Agency, Department of Innovation Research, Chief
  • 2010/11/01, 2014/03/31, Hiroshima University, Graduate School of Biomedical & Health Sciences, Assistant Professor (Special Appointment)

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Affiliated Academic Societies

  • International Association for Dental Research
  • Japan Prosthodontic Society
  • Japan Academy of Digital Dentistry
  • The Japanese Society for Dental Materials and Devices
  • Nippon Academy of Dental Technology
  • Japanese Society of Gerodontology
  • Japanese Orthodontic Society
  • Japanese Association for Medical Artificial Intelligence
  • Japan Dental Artificial Intelligence Study Group
  • Society for Regulatory Science of medical Products
  • Japanese Cancer Association
  • The Japanese Society for Regenerative Medicine
  • The Japanese Tissue Culture Association

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, First Semester, Special Study for Graduation
  2. 2024, Undergraduate Education, 4Term, Practice on Applied Biomaterial
  3. 2024, Undergraduate Education, 4Term, Practice in Crown Restoration and Health Engineering
  4. 2024, Undergraduate Education, 4Term, Practice of Removable Denture and Health
  5. 2024, Undergraduate Education, 4Term, Practice on Medical Design and Engineering
  6. 2024, Undergraduate Education, 4Term, Practice of Oral Process Engineering
  7. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  8. 2024, Undergraduate Education, Second Semester, Special Study for Graduation
  9. 2024, Graduate Education (Master's Program) , First Semester, Lecture on Oral Health Sciences
  10. 2024, Liberal Arts Education Program1, 4Term, General Health and Oral Sciences II
  11. 2024, Undergraduate Education, 4Term, Overview of Dentistry
  12. 2024, Undergraduate Education, 4Term, Research Start-Up
  13. 2024, Undergraduate Education, 2Term, Team Care for Oral Health
  14. 2024, Undergraduate Education, 4Term, Special Subject
  15. 2024, Undergraduate Education, 4Term, Research Start-Up
  16. 2024, Undergraduate Education, 2Term, Team Care for Oral Health
  17. 2024, Undergraduate Education, 1Term, Introductory course for oral engineering
  18. 2024, Undergraduate Education, 2Term, Practice on Stmatognathic System and Function
  19. 2024, Undergraduate Education, 1Term, Practice on Biomaterial
  20. 2024, Undergraduate Education, 2Term, Precision Casting Science
  21. 2024, Undergraduate Education, 2Term, Practice in Crown Restoration and Health Engineering (Inlay)
  22. 2024, Undergraduate Education, 4Term, Practice on Precision Casting Science
  23. 2024, Undergraduate Education, 3Term, Esthetic Dentistry
  24. 2024, Undergraduate Education, 4Term, Research Start-Up
  25. 2024, Undergraduate Education, 2Term, Team Care for Oral Health
  26. 2024, Undergraduate Education, 2Term, Practice of Removable Denture and Health (Anaplastology II)
  27. 2024, Undergraduate Education, Academic Year, Practical Training on Digital Dentistry
  28. 2024, Undergraduate Education, 3Term, Practice of Pediatric Dentistry
  29. 2024, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  30. 2024, Undergraduate Education, 3Term, Medical Design Engineering I
  31. 2024, Undergraduate Education, 4Term, Medical Design Engineering II
  32. 2024, Undergraduate Education, Second Semester, Special Study for Graduation
  33. 2024, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
  34. 2024, Graduate Education (Master's Program) , First Semester, Seminar on Translational Oral Sciences

Research Activities

Academic Papers

  1. Innovation from Dentistry: The Inside Story From Research to Patents, Licenses, and Royalty Income, Journal of Oral Tissue Engineering, 2023
  2. Evaluation of shade correspondence between high-translucency pre-colored zirconia and shade tab by considering the influence of cement shade and substrate materials, HELIYON, 9(12), 202312
  3. Optimizing Dental Bond Strength: Insights from Comprehensive Literature Review and Future Implications for Clinical Practice, BIOMEDICINES, 11(11), 202311
  4. The Physiological Function of Deglutition and Swallowing in Patients With Maxillary Protrusion After Mandibular Advancement, JOURNAL OF CRANIOFACIAL SURGERY, 34(7), 1966-1970, 202310
  5. Enhancing Dental Cement Bond Strength with Autofocus-Laser-Cutter-Generated Grooves on Polyetheretherketone Surfaces, POLYMERS, 15(18), 202309
  6. Effect of Various Airborne Particle Abrasion Conditions on Bonding between Polyether-Ether-Ketone (PEEK) and Dental Resin Cement, POLYMERS, 15(9), 20230428
  7. An in vitro study of digital impressions and three-dimensional printed models of orbital defects using mobile devices and monoscopic photogrammetry, JOURNAL OF ORAL SCIENCE, 65(2), 127-130, 202304
  8. Effects of the methyl methacrylate addition, polymerization temperature and time on the MBG@PMMA core-shell structure and its application as addition in electrospun composite fiber bioscaffold, CERAMICS INTERNATIONAL, 49(5), 7630-7639, 20230301
  9. Analysis of the feasibility of using deep learning for multiclass classification of dental anomalies on panoramic radiographs, DENTAL MATERIALS JOURNAL, 41(6), 889-895, 202212
  10. BMP and activin membrane-bound inhibitor regulate connective tissue growth factor controlling mesothelioma cell proliferation, BMC CANCER, 22(1), 20220915
  11. Detecting the presence of supernumerary teeth during the early mixed dentition stage using deep learning algorithms: A pilot study, INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY, 32(5), 678-685, 202209
  12. Influence of dental abrasives on surface roughness, gloss, and color of titanium, JOURNAL OF ORAL SCIENCE, 64(3), 247-250, 202207
  13. Lansoprazole and zoledronate delays hard tissue healing of tooth extraction sockets in dexamethasone-treated mice, BIOMEDICINE & PHARMACOTHERAPY, 150, 202206
  14. Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning, SCIENTIFIC REPORTS, 202201
  15. Alterations to titanium surface depending on the fluorides and abrasives in toothpaste, MATERIALS, 202201
  16. Occlusal Trauma and Bisphosphonate-Related Osteonecrosis of the Jaw in Mice, CALCIFIED TISSUE INTERNATIONAL, 202109
  17. Landmark annotation and mandibular lateral deviation analysis of posteroanterior cephalograms using a convolutional neural network, JOURNAL OF DENTAL SCIENCES, 202107
  18. In vivo Efficacy of Lacticaseibacillus rhamnosus L8020 in a Mouse Model of Oral Candidiasis, JOURNAL OF FUNGI, 202105
  19. Biofilm formation on the surface of (poly)ether-ether-ketone and in vitro antimicrobial efficacy of photodynamic therapy on peri-implant mucositis, POLYMERS, 202103
  20. Mesoporous properties of bioactive glass synthesized by spray pyrolysis with various polyethylene glycol and acid additions, POLYMERS, 202102
  21. Accuracy Evaluation of a Three-Dimensional Model Generated from Patient-Specific Monocular Video Data for Maxillofacial Prosthetic Rehabilitation: A Pilot Study, JOURNAL OF PROSTHODONTICS, 202010
  22. Comprehensive analysis of transcriptional profiles in oral epithelial-like cells stimulated with oral probiotic Lactobacillus spp., ARCHIVES OF ORAL BIOLOGY, 118, 104832, 202010
  23. Cytotoxicity assay using a human pluripotent stem cell–derived cranial neural crest cell model, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL, 505-510, 202008
  24. Applying deep artificial neural network approach to maxillofacial prostheses coloration, JOURNAL OF PROSTHODONTIC RESEARCH, 64(3), 296-300, 202007
  25. Assembly Sequence Planning by Probabilistic Tree Transformation, EMITTER-INTERNATIONAL JOURNAL OF ENGINEERING TECHNOLOGY, 6(2), 354-368, 2018
  26. Biomimetic Peptides for the Treatment of Cancer, ANTICANCER RESEARCH, 36(7), 3565-3570, 2016
  27. Inhibition of RANKL-dependent cellular fusion in pre-osteoclasts by amiloride and a NHE10-specific monoclonal antibody, CELL BIOLOGY INTERNATIONAL, 39(6), 696-709, 2015
  28. Involvement of ERK and p38 MAPK pathways on Interleukin-33-induced RANKL expression in osteoblastic cells, CELL BIOLOGY INTERNATIONAL, 38(5), 655-662, 2014
  29. Impact of Biomimetic Diamond-like Carbon coated Titanium on Osteoblast and Osteoclast Differentiation in vitro, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 27(3), 373-378, 2014
  30. Biomimetic Diamond-like Carbon coated Titanium Inhibits RANKL-dependent Osteoclast Differentiation in vitro, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 25(4), 523-528, 2012
  31. Blocking of sodium and potassium ion-dependent adenosine triphosphatase-alpha 1 with ouabain and vanadate suppresses cell-cell fusion during RANKL-mediated osteoclastogenesis, EUROPEAN JOURNAL OF PHARMACOLOGY, 670(2-3), 409-418, 2011
  32. Evaluation of trabecular bone formation in a canine model surrounding a dental implant fixture immobilized with an antimicrobial peptide derived from histatin, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 22(12), 2765-2772, 2011
  33. Bovine milk fermented with Lactobacillus rhamnosus L8020 decreases the oral carriage of mutans streptococci and the burden of periodontal pathogens, JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY, 2(2), 1-10, 2011
  34. Impact of titanium ions on osteoblast-, osteoclast- and gingival epithelial-like cells, JOURNAL OF PROSTHODONTIC RESEARCH, 54(1), 1-6, 2010
  35. Immobilized-OPG-Fc on a titanium surface inhibits RANKL-dependent osteoclast differentiation in vitro, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 21(2), 647-653, 2010
  36. Titanium Immobilized with an Antimicrobial Peptide Derived from Histatin Accelerates the Differentiation of Osteoblastic Cell Line, MC3T3-E1, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 11(4), 1458-1470, 2010
  37. Titanium ion induces necrosis and sensitivity to lipopolysaccharide in gingival epithelial-like cells, TOXICOLOGY IN VITRO, 24(7), 1905-1910, 2010
  38. Impact of the microgravity environment in a 3-dimensional clinostat on osteoblast- and osteoclast-like cells, CELL BIOLOGY INTERNATIONAL, 32(9), 1176-1181, 2008
  39. Titanium surface roughness accelerates RANKL-dependent differentiation in the osteoclast precursor cell line, RAW264.7, DENTAL MATERIALS JOURNAL, 26(5), 739-745, 2007

Invited Lecture, Oral Presentation, Poster Presentation

  1. Dental Anomaly Detection Using RadImageNet Transfer Learning Models, Okazaki S, Mine Y, Iwamoto Y, Nishimura T, Nomura R, Murayama T, Joint 37th IADR-SEA Annual Scientific Meeting and 2nd International Oral Health Symposium, 2023/11/25, Without Invitation, English
  2. Regulation of bone-related cell differentiation by synthetic BMP-2 peptide and RANKL-binding peptide, Shuto T, Mine Y, Tani A, International Dental Materials Congress 2022, 2022/11/04, Without Invitation, English
  3. Analysis of mandibular lateral deviation on posteroanterior cephalograms using a deep learning algorithm, Okazaki S, Mine Y, Yoshimi Y, Ito S, Takeda S, Tanimoto K, Murayama T, International Dental Materials Congress 2022, 2022/11/04, Without Invitation, English
  4. Multiclass Classification of Odontoma and Supernumerary Tooth Using Deep Learning, Okazaki S, Mine Y, Iwamoto Y, Urabe S, Mitsuhata C, Murayama T, 2022 IADR/APR General Session & Exhibition, 2022/06/20, Without Invitation, English
  5. Artificial Intelligence in Dentistry: Current Status of Deep Learning Studies, Mine Y, The 2nd International Symposium on Digital Dentistry and Biomedical Materials, 2022/05/26, With Invitation, English
  6. Grad-CAM Helps Explainability of Supernumerary Teeth Detection by Deep Learning, Okazaki S, Mine Y, Iwamoto Y, Takeda S, Mitsuhata C, Murayama T, The 35th Annual Scientific Meeting of International Association of Dental Research - South East Asia Division (IADR-SEA), 2021/12/09, Without Invitation, English
  7. Mandibular lateral deviation detection of posteroanterior cephalograms using a deep learning approach, Okazaki S, Mine Y, Yoshimi Y, Ito S, Takeda S, Tanimoto K, Murayama T, The 6th Joint Scientific Meeting in Dentistry (JSMiD) 2021, 2021/08/01, Without Invitation, English
  8. Artificial Intelligence in Medicine and Dentistry, Mine Y, The 6th Joint Scientific Meeting in Dentistry (JSMiD) 2021, 2021/07/30, With Invitation, English
  9. Lacticaseibacillus rhamnosus L8020 and Murine Oral Candidiasis Model, Hamaoka M, Mine Y, Ito R, Yumisashi Y, Yoshioka R, Taji T, Murayama T, Nikawa H, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/24, Without Invitation, English
  10. Evaluation of Extraction Socket Healing in Zoledronate-medicated Mice Combining Lansoprazole, Yoshioka R, Mine Y, Nikawa H, Murayama T, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/21, Without Invitation, English
  11. Detection of Supernumerary Teeth Using Deep Learning Approach, Takeda S, Mine Y, Iwamoto Y, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/21, Without Invitation, English
  12. Detection of Supernumerary Teeth during Early Mixed Dentition Stage with Deep Learning-based Convolutional Neural Network Algorithms, Mine Y, Iwamoto Y, Takeda S, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 28th Congress of the IAPD, 2021/06/10, Without Invitation, English
  13. Lansoprazole Delays Extraction Socket Healing in Bisphosphonate-medicated Mice, Yoshioka R, Mine Y, Nikawa H, Murayama T, The 34th Annual Scientific Meeting of International Association of Dental Research - South East Asia Division (IADR-SEA) Virtual Meeting, 2020/11/26, Without Invitation, English
  14. Detection of Dental and Oral Anomalies with Machine Learning: Comparison between Convolutional Neural Networks and Random Forest, Nakamura K, Mine Y, Iwamoto Y, Takeda S, Mitsuhata C, Kozai K, Murayama T, IAPD20 Virtual (International Association of Paediatric Dentistry), 2020/09/13, Without Invitation, English
  15. Evaluation of alveolar bone in bisphosphonate-medicated mice with hyperocclusive state, Okuda K, Mine Y, Nikawa H, Murayama T, 4th Meeting of the International Association for Dental Research and Asia Pacific Region 2019, 2019/11/28, Without Invitation, English
  16. Detection of Dental and Oral Anomalies Using Deep Learning Approach, Mine Y, Iwamoto Y, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 2019 IADR/AADR/CADR General Session & Exhibition, 2019/06/19, Without Invitation, English
  17. A synthetic peptide derived from the sibling protein mepe inhibits ectopic mineralization but not bone formation, Minamizaki T, Toshishige M, Yoshioka H, Ahmed F, Mine Y, Yoshiko Y, World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2019), 2019/04/07, Without Invitation, English
  18. Current Status of Translational Research for Development of Pharmaceutical and Regenerative Medical Products in Academia, Mine Y, Murayama T, The 51st Annual Meeting of Hiroshima University Dental Society, 2018/06/09, Without Invitation, English

Patented

  1. Patent, 9138507, Method for manufacturing an implant material