YUICHI MINE

Last Updated :2025/06/30

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Associate Professor/Lecturer

Basic Information

Major Professional Backgrounds

  • 2018/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Lecturer
  • 2018/04/01, 2020/03/31, Hiroshima University, Translational Research Center, Department Head
  • 2017/04/01, 2018/03/31, Kyushu University, School of Medical Sciences, Lecturer
  • 2017/06/14, 2017/07/14, National Center for Advancing Translational Sciences, Division of Pre-Clinical Innovation, Special Volunteer
  • 2015/10/01, 2017/03/31, Kyushu University, School of Medical Sciences, Assistant Professor
  • 2014/04/01, 2015/09/30, Japan Science and Technology Agency, Department of Innovation Research, Chief
  • 2010/11/01, 2014/03/31, Hiroshima University, Graduate School of Biomedical & Health Sciences, Assistant Professor (Special Appointment)

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Affiliated Academic Societies

  • International Association for Dental Research
  • Japan Prosthodontic Society
  • Japan Academy of Digital Dentistry
  • The Japanese Society for Dental Materials and Devices
  • Nippon Academy of Dental Technology
  • Japanese Society of Gerodontology
  • Japanese Orthodontic Society
  • Japanese Association for Medical Artificial Intelligence
  • Japan Dental Artificial Intelligence Study Group
  • Society for Regulatory Science of medical Products
  • Japanese Cancer Association
  • The Japanese Society for Regenerative Medicine
  • The Japanese Tissue Culture Association

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 4Term, General Health and Oral Sciences II
  2. 2025, Undergraduate Education, 4Term, Overview of Dentistry
  3. 2025, Undergraduate Education, 4Term, Research Start-Up
  4. 2025, Undergraduate Education, 2Term, Team Care for Oral Health
  5. 2025, Undergraduate Education, 4Term, Special Subject
  6. 2025, Undergraduate Education, 4Term, Research Start-Up
  7. 2025, Undergraduate Education, 2Term, Team Care for Oral Health
  8. 2025, Undergraduate Education, 1Term, Introductory Course for Oral Engineering
  9. 2025, Undergraduate Education, 2Term, Practice on Stmatognathic System and Function
  10. 2025, Undergraduate Education, 1Term, Practice on Biomaterial
  11. 2025, Undergraduate Education, 2Term, Precision Casting Science
  12. 2025, Undergraduate Education, 2Term, Practice in Crown Restoration and Health Engineering (Inlay)
  13. 2025, Undergraduate Education, 4Term, Practice on Precision Casting Science
  14. 2025, Undergraduate Education, 3Term, Esthetic Dentistry
  15. 2025, Undergraduate Education, 4Term, Research Start-Up
  16. 2025, Undergraduate Education, 2Term, Team Care for Oral Health
  17. 2025, Undergraduate Education, 2Term, Practice of Removable Denture and Health (Anaplastology II)
  18. 2025, Undergraduate Education, Year, Practical Training on Digital Dentistry
  19. 2025, Undergraduate Education, 3Term, Practice of Pediatric Dentistry
  20. 2025, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  21. 2025, Undergraduate Education, 3Term, Medical Design Engineering I
  22. 2025, Undergraduate Education, 4Term, Medical Design Engineering II
  23. 2025, Undergraduate Education, Second Semester, Special Study for Graduation
  24. 2025, Undergraduate Education, First Semester, Clinical Practice in Oral Health Engineering
  25. 2025, Undergraduate Education, First Semester, Special Study for Graduation
  26. 2025, Undergraduate Education, 4Term, Practice on Applied Biomaterial
  27. 2025, Undergraduate Education, 4Term, Practice in Crown Restoration and Health Engineering
  28. 2025, Undergraduate Education, 4Term, Practice of Removable Denture and Health
  29. 2025, Undergraduate Education, 4Term, Practice on Medical Design and Engineering
  30. 2025, Undergraduate Education, 4Term, Practice of Oral Process Engineering
  31. 2025, Undergraduate Education, Second Semester, Clinical Practice in Oral Health Engineering
  32. 2025, Undergraduate Education, Second Semester, Special Study for Graduation
  33. 2025, Graduate Education (Master's Program) , First Semester, Lecture on Oral Health Sciences
  34. 2025, Graduate Education (Master's Program) , First Semester, Seminar on Translational Oral Sciences

Research Activities

Academic Papers

  1. Analysis of Risedronate Analog on Extraction Socket Healing in Mice, IN VIVO, 39(2), 648-655, 2025
    Link to Paper Search Results by DOI
  2. RadImageNet and ImageNet as Datasets for Transfer Learning in the Assessment of Dental Radiographs: A Comparative Study, JOURNAL OF IMAGING INFORMATICS IN MEDICINE, 38(1), 534-544, 202502
    Link to Paper Search Results by DOI
  3. Anti-fungal effects of slightly acidic electrolyzed water on Candida species, JOURNAL OF ORAL BIOSCIENCES, 67(1), 202503
    Link to Paper Search Results by DOI
  4. Activation of platelet-derived growth factor receptors regulate connective tissue growth factor protein levels via the AKT pathway in malignant mesothelioma cells, JOURNAL OF BIOCHEMISTRY, 176(6), 460-471, 20241023
    Link to Paper Search Results by DOI
  5. Prediction of a Cephalometric Parameter and Skeletal Patterns from Lateral Profile Photographs: A Retrospective Comparative Analysis of Regression Convolutional Neural Networks, JOURNAL OF CLINICAL MEDICINE, 13(21), 202411
    Link to Paper Search Results by DOI
  6. Sex estimation from maxillofacial radiographs using a deep learning approach, DENTAL MATERIALS JOURNAL, 43(3), 202406
    Link to Paper Search Results by DOI
  7. Effects of handheld nonthermal plasma on the biological responses, mineralization, and inflammatory reactions of polyaryletherketone implant materials, JOURNAL OF DENTAL SCIENCES, 19(4), 2018-2026, 202410
    Link to Paper Search Results by DOI
  8. Image preprocessing with contrast-limited adaptive histogram equalization improves the segmentation performance of deep learning for the articular disk of the temporomandibular joint on magnetic resonance images, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 138(1), 128-141, 202407
    Link to Paper Search Results by DOI
  9. Fracture characteristics and translucency of multilayer monolithic zirconia crowns of various thicknesses, JOURNAL OF DENTISTRY, 145, 202406
    Link to Paper Search Results by DOI
  10. Innovation from Dentistry: The Inside Story From Research to Patents, Licenses, and Royalty Income, Journal of Oral Tissue Engineering, 2023
  11. Evaluation of shade correspondence between high-translucency pre-colored zirconia and shade tab by considering the influence of cement shade and substrate materials, HELIYON, 9(12), 202312
    Link to Paper Search Results by DOI
  12. Optimizing Dental Bond Strength: Insights from Comprehensive Literature Review and Future Implications for Clinical Practice, BIOMEDICINES, 11(11), 202311
    Link to Paper Search Results by DOI
  13. The Physiological Function of Deglutition and Swallowing in Patients With Maxillary Protrusion After Mandibular Advancement, JOURNAL OF CRANIOFACIAL SURGERY, 34(7), 1966-1970, 202310
    Link to Paper Search Results by DOI
  14. Enhancing Dental Cement Bond Strength with Autofocus-Laser-Cutter-Generated Grooves on Polyetheretherketone Surfaces, POLYMERS, 15(18), 202309
    Link to Paper Search Results by DOI
  15. Effect of Various Airborne Particle Abrasion Conditions on Bonding between Polyether-Ether-Ketone (PEEK) and Dental Resin Cement, POLYMERS, 15(9), 20230428
    Link to Paper Search Results by DOI
  16. An in vitro study of digital impressions and three-dimensional printed models of orbital defects using mobile devices and monoscopic photogrammetry, JOURNAL OF ORAL SCIENCE, 65(2), 127-130, 202304
    Link to Paper Search Results by DOI
  17. Effects of the methyl methacrylate addition, polymerization temperature and time on the MBG@PMMA core-shell structure and its application as addition in electrospun composite fiber bioscaffold, CERAMICS INTERNATIONAL, 49(5), 7630-7639, 20230301
    Link to Paper Search Results by DOI
  18. Analysis of the feasibility of using deep learning for multiclass classification of dental anomalies on panoramic radiographs, DENTAL MATERIALS JOURNAL, 41(6), 889-895, 202212
    Link to Paper Search Results by DOI
  19. BMP and activin membrane-bound inhibitor regulate connective tissue growth factor controlling mesothelioma cell proliferation, BMC CANCER, 22(1), 20220915
    Link to Paper Search Results by DOI
  20. Detecting the presence of supernumerary teeth during the early mixed dentition stage using deep learning algorithms: A pilot study, INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY, 32(5), 678-685, 202209
    Link to Paper Search Results by DOI
  21. Influence of dental abrasives on surface roughness, gloss, and color of titanium, JOURNAL OF ORAL SCIENCE, 64(3), 247-250, 202207
    Link to Paper Search Results by DOI
  22. Lansoprazole and zoledronate delays hard tissue healing of tooth extraction sockets in dexamethasone-treated mice, BIOMEDICINE & PHARMACOTHERAPY, 150, 202206
    Link to Paper Search Results by DOI
  23. Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning, SCIENTIFIC REPORTS, 202201
  24. Alterations to titanium surface depending on the fluorides and abrasives in toothpaste, MATERIALS, 202201
  25. Occlusal Trauma and Bisphosphonate-Related Osteonecrosis of the Jaw in Mice, CALCIFIED TISSUE INTERNATIONAL, 202109
  26. Landmark annotation and mandibular lateral deviation analysis of posteroanterior cephalograms using a convolutional neural network, JOURNAL OF DENTAL SCIENCES, 202107
  27. In vivo Efficacy of Lacticaseibacillus rhamnosus L8020 in a Mouse Model of Oral Candidiasis, JOURNAL OF FUNGI, 202105
  28. Biofilm formation on the surface of (poly)ether-ether-ketone and in vitro antimicrobial efficacy of photodynamic therapy on peri-implant mucositis, POLYMERS, 202103
  29. Mesoporous properties of bioactive glass synthesized by spray pyrolysis with various polyethylene glycol and acid additions, POLYMERS, 202102
  30. Accuracy Evaluation of a Three-Dimensional Model Generated from Patient-Specific Monocular Video Data for Maxillofacial Prosthetic Rehabilitation: A Pilot Study, JOURNAL OF PROSTHODONTICS, 202010
  31. Comprehensive analysis of transcriptional profiles in oral epithelial-like cells stimulated with oral probiotic Lactobacillus spp., ARCHIVES OF ORAL BIOLOGY, 118, 104832, 202010
  32. Cytotoxicity assay using a human pluripotent stem cell–derived cranial neural crest cell model, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL, 505-510, 202008
  33. Applying deep artificial neural network approach to maxillofacial prostheses coloration, JOURNAL OF PROSTHODONTIC RESEARCH, 64(3), 296-300, 202007
  34. Assembly Sequence Planning by Probabilistic Tree Transformation, EMITTER-INTERNATIONAL JOURNAL OF ENGINEERING TECHNOLOGY, 6(2), 354-368, 2018
  35. Biomimetic Peptides for the Treatment of Cancer, ANTICANCER RESEARCH, 36(7), 3565-3570, 2016
  36. Inhibition of RANKL-dependent cellular fusion in pre-osteoclasts by amiloride and a NHE10-specific monoclonal antibody, CELL BIOLOGY INTERNATIONAL, 39(6), 696-709, 2015
  37. Involvement of ERK and p38 MAPK pathways on Interleukin-33-induced RANKL expression in osteoblastic cells, CELL BIOLOGY INTERNATIONAL, 38(5), 655-662, 2014
  38. Impact of Biomimetic Diamond-like Carbon coated Titanium on Osteoblast and Osteoclast Differentiation in vitro, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 27(3), 373-378, 2014
  39. Biomimetic Diamond-like Carbon coated Titanium Inhibits RANKL-dependent Osteoclast Differentiation in vitro, JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY, 25(4), 523-528, 2012
  40. Blocking of sodium and potassium ion-dependent adenosine triphosphatase-alpha 1 with ouabain and vanadate suppresses cell-cell fusion during RANKL-mediated osteoclastogenesis, EUROPEAN JOURNAL OF PHARMACOLOGY, 670(2-3), 409-418, 2011
  41. Evaluation of trabecular bone formation in a canine model surrounding a dental implant fixture immobilized with an antimicrobial peptide derived from histatin, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 22(12), 2765-2772, 2011
  42. Bovine milk fermented with Lactobacillus rhamnosus L8020 decreases the oral carriage of mutans streptococci and the burden of periodontal pathogens, JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY, 2(2), 1-10, 2011
  43. Impact of titanium ions on osteoblast-, osteoclast- and gingival epithelial-like cells, JOURNAL OF PROSTHODONTIC RESEARCH, 54(1), 1-6, 2010
  44. Immobilized-OPG-Fc on a titanium surface inhibits RANKL-dependent osteoclast differentiation in vitro, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 21(2), 647-653, 2010
  45. Titanium Immobilized with an Antimicrobial Peptide Derived from Histatin Accelerates the Differentiation of Osteoblastic Cell Line, MC3T3-E1, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 11(4), 1458-1470, 2010
  46. Titanium ion induces necrosis and sensitivity to lipopolysaccharide in gingival epithelial-like cells, TOXICOLOGY IN VITRO, 24(7), 1905-1910, 2010
  47. Impact of the microgravity environment in a 3-dimensional clinostat on osteoblast- and osteoclast-like cells, CELL BIOLOGY INTERNATIONAL, 32(9), 1176-1181, 2008
  48. Titanium surface roughness accelerates RANKL-dependent differentiation in the osteoclast precursor cell line, RAW264.7, DENTAL MATERIALS JOURNAL, 26(5), 739-745, 2007

Invited Lecture, Oral Presentation, Poster Presentation

  1. Age estimation from lateral cephalograms using a deep learning approach, Yoshimi Y, Mine Y, Murayama T, Tanimoto K, 2024 TAO APOC 37th Annual Meeting of TAO 14th Asia Pacific Orthodontic Congress, 2024/12/03, Without Invitation, English
  2. Fully automated teeth detection from mixed dentition panoramic radiographs using deep learning object detection model, Nishimura T, Iwamoto Y, Mine Y, Okazaki S, Tabata E, Murayama T, Nomura R, 13th Biennial Conference of the Pediatric Dentistry Association of Asia (PDAA), 2024/10/30, Without Invitation, English
  3. Dental Anomaly Detection Using RadImageNet Transfer Learning Models, Okazaki S, Mine Y, Iwamoto Y, Nishimura T, Nomura R, Murayama T, Joint 37th IADR-SEA Annual Scientific Meeting and 2nd International Oral Health Symposium, 2023/11/25, Without Invitation, English
  4. Regulation of bone-related cell differentiation by synthetic BMP-2 peptide and RANKL-binding peptide, Shuto T, Mine Y, Tani A, International Dental Materials Congress 2022, 2022/11/04, Without Invitation, English
  5. Analysis of mandibular lateral deviation on posteroanterior cephalograms using a deep learning algorithm, Okazaki S, Mine Y, Yoshimi Y, Ito S, Takeda S, Tanimoto K, Murayama T, International Dental Materials Congress 2022, 2022/11/04, Without Invitation, English
  6. Multiclass Classification of Odontoma and Supernumerary Tooth Using Deep Learning, Okazaki S, Mine Y, Iwamoto Y, Urabe S, Mitsuhata C, Murayama T, 2022 IADR/APR General Session & Exhibition, 2022/06/20, Without Invitation, English
  7. Artificial Intelligence in Dentistry: Current Status of Deep Learning Studies, Mine Y, The 2nd International Symposium on Digital Dentistry and Biomedical Materials, 2022/05/26, With Invitation, English
  8. Grad-CAM Helps Explainability of Supernumerary Teeth Detection by Deep Learning, Okazaki S, Mine Y, Iwamoto Y, Takeda S, Mitsuhata C, Murayama T, The 35th Annual Scientific Meeting of International Association of Dental Research - South East Asia Division (IADR-SEA), 2021/12/09, Without Invitation, English
  9. Mandibular lateral deviation detection of posteroanterior cephalograms using a deep learning approach, Okazaki S, Mine Y, Yoshimi Y, Ito S, Takeda S, Tanimoto K, Murayama T, The 6th Joint Scientific Meeting in Dentistry (JSMiD) 2021, 2021/08/01, Without Invitation, English
  10. Artificial Intelligence in Medicine and Dentistry, Mine Y, The 6th Joint Scientific Meeting in Dentistry (JSMiD) 2021, 2021/07/30, With Invitation, English
  11. Lacticaseibacillus rhamnosus L8020 and Murine Oral Candidiasis Model, Hamaoka M, Mine Y, Ito R, Yumisashi Y, Yoshioka R, Taji T, Murayama T, Nikawa H, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/24, Without Invitation, English
  12. Evaluation of Extraction Socket Healing in Zoledronate-medicated Mice Combining Lansoprazole, Yoshioka R, Mine Y, Nikawa H, Murayama T, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/21, Without Invitation, English
  13. Detection of Supernumerary Teeth Using Deep Learning Approach, Takeda S, Mine Y, Iwamoto Y, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 2021 IADR/AADR/CADR General Session & Exhibition, 2021/07/21, Without Invitation, English
  14. Detection of Supernumerary Teeth during Early Mixed Dentition Stage with Deep Learning-based Convolutional Neural Network Algorithms, Mine Y, Iwamoto Y, Takeda S, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 28th Congress of the IAPD, 2021/06/10, Without Invitation, English
  15. Lansoprazole Delays Extraction Socket Healing in Bisphosphonate-medicated Mice, Yoshioka R, Mine Y, Nikawa H, Murayama T, The 34th Annual Scientific Meeting of International Association of Dental Research - South East Asia Division (IADR-SEA) Virtual Meeting, 2020/11/26, Without Invitation, English
  16. Detection of Dental and Oral Anomalies with Machine Learning: Comparison between Convolutional Neural Networks and Random Forest, Nakamura K, Mine Y, Iwamoto Y, Takeda S, Mitsuhata C, Kozai K, Murayama T, IAPD20 Virtual (International Association of Paediatric Dentistry), 2020/09/13, Without Invitation, English
  17. Evaluation of alveolar bone in bisphosphonate-medicated mice with hyperocclusive state, Okuda K, Mine Y, Nikawa H, Murayama T, 4th Meeting of the International Association for Dental Research and Asia Pacific Region 2019, 2019/11/28, Without Invitation, English
  18. Detection of Dental and Oral Anomalies Using Deep Learning Approach, Mine Y, Iwamoto Y, Nakamura K, Mitsuhata C, Kozai K, Murayama T, 2019 IADR/AADR/CADR General Session & Exhibition, 2019/06/19, Without Invitation, English
  19. A synthetic peptide derived from the sibling protein mepe inhibits ectopic mineralization but not bone formation, Minamizaki T, Toshishige M, Yoshioka H, Ahmed F, Mine Y, Yoshiko Y, World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2019), 2019/04/07, Without Invitation, English
  20. Application of dispatching rules for dental technical work and its evaluation by discrete-event simulatio, Yanase H, Mine Y, Eguchi T, Murayama T, 1st Meeting of the International Oral Engineering Consortium, 2018/09/24, Without Invitation, English
  21. Current Status of Translational Research for Development of Pharmaceutical and Regenerative Medical Products in Academia, Mine Y, Murayama T, The 51st Annual Meeting of Hiroshima University Dental Society, 2018/06/09, Without Invitation, English

Patented

  1. Patent, 9138507, Method for manufacturing an implant material