YASUYUKI KINOSHITA

Last Updated :2026/07/18

Affiliations, Positions
Hiroshima University Hospital, Associate Professor/Lecturer
E-mail
y-kinoshitahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • MD, PhD, Hiroshima University

Affiliated Academic Societies

  • The Japan Neurosurgical Society
  • The Japanese Congress of Neurological Surgeons
  • The japan Society for Hypothalamic and Pituitary Tumors
  • The Japan Endocrine Society
  • The Japanese Society for Neuroendoscopy
  • The Pituitary Society
  • The Japanese Congress of Brain Tumor Surgery
  • Conference on Neurosurgical Techniques and Tools
  • The Japan Brain Dock Society
  • The Japan Society for CNS Computed Imaging
  • Japan Society for Surgical Infection
  • Japanese Society of Clinical Sports Medicine
  • The Japanese Headache Society

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, Year, Medical Neuroscience III

Research Activities

Academic Papers

  1. Possible involvement of genome-wide near-haploidy and MEN1 mutation in the molecular pathogenesis of pituitary carcinoma: Analysis by whole exome sequencing, Neuro-Oncology Advances, 8(1), vdag146, 20260602
    Link to Paper Search Results by DOI
  2. A multicorridor strategy including the infralabyrinthine route for extensive skull base chondrosarcoma, Journal of Neurosurgery: Case Lessons, 11, CASE2618, 20260227
  3. Automatic acromegaly detection using deep learning on hand images: a multicenter observational study, Journal of Clinical Endocrinology & Metabolism, online ahead, 2026
  4. Automatic acromegaly detection using deep learning on hand images: a multicenter observational study, Journal of Clinical Endocrinology & Metabolism, 20260227
    Link to Paper Search Results by DOI
  5. Differences in clinical course between pituitary apoplexy and non-apoplexy patients with nonfunctioning pituitary neuroendocrine Tumors, Neurosurgical Review, 49(1), 247, 20260225
    Link to Paper Search Results by DOI
  6. Imaging characteristics and treatment of recurrent germinoma., Journal of Neurosurgery, online ahead, 20250124
  7. ★, Management policy for postoperative acromegaly patients with normal IGF-1 and high GH levels on oral glucose tests, Pituitary, 26(1), 4, 20241226
    Link to Paper Search Results by DOI
  8. ★, Pseudocapsular resection to prevent recurrence in nonfunctioning pituitary neuroendocrine tumors with more than 5 years of follow-up: a retrospective, single-center study, Journal of Neurosurgery, 142(1), 224, 20240802
    Link to Paper Search Results by DOI
  9. Blood culture bottles for culturing cerebrospinal fluid in cases of bacterial meningitis caused by Enterococcus faecalis: A case report, Journal of Infection and Chemotherapy, 20240524
    Link to Paper Search Results by DOI
  10. Characteristics of radiation-induced brain tumors from our case series and systematic review, Journal of Neurosurgery, 141(6), 1614, 20240607
    Link to Paper Search Results by DOI
  11. Differences in invasiveness and recurrence rate among nonfunctioning pituitary neuroendocrine tumors depending on tumor subtype, Neurosurg Rev, 46(1), 317, 20231130
    Link to Paper Search Results by DOI
  12. Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report, Cureus, 2023
  13. Characteristics and therapeutic strategies of brain and cranial radiation-induced sarcoma: analysis of 165 cases from our case experience and comprehensive review, Japanese Journal of Clinical Oncology, 2023
    Link to Paper Search Results by DOI
  14. Optic tract edema in craniopharyngioma as a predictor of BRAFV600E mutation presence, Japanese Journal of Clinical Oncology, 53(5), 378-385, 20230429
    Link to Paper Search Results by DOI
  15. Usefulness of critical flicker fusion frequency measurement and its laterality for evaluating compressive optic neuropathy due to pituitary neuroendocrine tumors, Neurosurgical Review, 46(1), 4, 202212
    Link to Paper Search Results by DOI
  16. ★, Natural course of Rathke's cleft cysts and risk factors for progression., Journal of Neurosurgery, 138(5), 1426-1432, 202209
    Link to Paper Search Results by DOI
  17. ★, Influence of growth hormone therapy on germinoma survivors, Pituitary, 25(6), 854-860, 202212
    Link to Paper Search Results by DOI
  18. ★, Predictive factors for recovery from adult growth hormone deficiency after transsphenoidal surgery for non-functioning pituitary adenoma, Journal of Neurosurgery, 25(1), 100-107, 2022
    Link to Paper Search Results by DOI
  19. ★, Isolated neurohypophysial sarcoidosis involving cavernous sinus mimicking malignant tumor, NMC Case Report Journal, 9, 31-35, 2022
    Link to Paper Search Results by DOI
  20. Intratumoral hemorrhage after endoscopic third ventriculostomy for obstructive hydrocephalus caused by brain tumors., World Neurosurgery, 158, e258-e264, 2022
    Link to Paper Search Results by DOI
  21. ★, Predictive factors of postoperative diabetes insipidus in 333 patients undergoing transsphenoidal surgery for non-functioning pituitary adenoma, Pituitary, 25(1), 100-107, 202202
    Link to Paper Search Results by DOI
  22. Metachronous double pituitary adenoma with altered transcriptional factor profile: a case report and literature review, NMC Case Report, 8(1), 657-663, 20211007
    Link to Paper Search Results by DOI
  23. ★, Pseudocapsular resection in elderly patients with non-functioning pituitary adenoma, Clinical Neurology and Neurosurgery, 210, 106997, 202111
    Link to Paper Search Results by DOI
  24. Clinical characteristics and thyroid hormone dynamics of thyrotropin-secreting pituitary adenomas at a single institution, Endocrine, 73(1), 151-159, 202107
    Link to Paper Search Results by DOI
  25. Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor, Eur J Radiol, 136, 109523, 202103
    Link to Paper Search Results by DOI
  26. Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature., World Neurosurgery, 134, e360-e371, 202002
    Link to Paper Search Results by DOI
  27. ★, Physiologic pituitary hyperplasia causing visual disturbance during adolescence, Journal of Clinical Neuroscience, 2019
    Link to Paper Search Results by DOI
  28. Sellar xanthogranuloma: a quest based on nine cases assessed with anterior pituitary provocation test., World Neurosurg, 2019
    Link to Paper Search Results by DOI
  29. ★, Nonfunctioning pituitary adenomas in elder patients, Journal of Clinical Neuroscience, 53, 127-131, 201807
    Link to Paper Search Results by DOI
  30. Factors Related to Frailty Associated with Clinical Deterioration After Meningioma Surgery in the Elderly., World neurosurgery, 201807
    Link to Paper Search Results by DOI
  31. Postoperative changes in metabolic parameters of patients with surgically controlled acromegaly: assessment of new stringent cure criteria, Neurol Med Chir (Tokyo), 58(4), 137, 201804
    Link to Paper Search Results by DOI
  32. Proton MRS detection of high lipid levels and low ADC is characteristics of germinoma., World Neurosurgery, 112, 84, 201804
    Link to Paper Search Results by DOI
  33. Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma., Neurosurg Focus, 44(4), E14, 201804
    Link to Paper Search Results by DOI
  34. ★, Pitfalls of a neuroendoscopic biopsy of intraventricular germ cell tumors, WORLD NEUROSURGERY, 106, 430-434, 201710
    Link to Paper Search Results by DOI
  35. Preoperative and Postoperative Pituitary Function in Patients with Tuberculum Sellae Meningioma -Based on Pituitary Provocation Tests., Neurol Med Chir (Tokyo), 57(10), 548-556, 201710
    Link to Paper Search Results by DOI
  36. Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma., Neurol Med Chir (Tokyo), 57(10), 521-533, 201710
    Link to Paper Search Results by DOI
  37. A Case of Intradural Retroclival Chordoma, No Shinkei Geka, 45, 623-627, 201707
  38. ★, Transsphenoidal posterior pituitary lobe biopsy in patients with neurohypophysial lesions., WORLD NEUROSURGERY, 99, 543-547, 201703
    Link to Paper Search Results by DOI
  39. Changes in quality of life in patients with acromegaly after surgical remission - A prospective study using SF-36 questionnaire., ENDOCRINE JOURNAL, 64(1), 27-38, 201701
    Link to Paper Search Results by DOI
  40. Effect of Gonadotropin and Adrenocorticotropic Hormone Secretion on Invasiveness of Clinically Nonfunctioning Pituitary Adenomas: A Cell Culture Study., WORLD NEUROSURGERY, 96, 578-584, 201612
    Link to Paper Search Results by DOI
  41. ★, The long-term recurrence of Rathke's cleft cysts as predicted by histology but not by surgical procedure, JOURNAL OF NEUROSURGERY, 125(4), 1002-1007, 201610
    Link to Paper Search Results by DOI
  42. Treatable glomerular hyperfiltration in patients with active acromegaly, EUROPEAN JOURNAL OF ENDOCRINOLOGY, 175(4), 325-333, 201610
    Link to Paper Search Results by DOI
  43. ★, The Surgical Side Effects of Pseudocapsular Resection in Nonfunctioning Pituitary Adenomas., WORLD NEUROSURGERY, 93, 430-435, 201609
    Link to Paper Search Results by DOI
  44. ★, Solitary Langerhans cell histiocytosis located in the neurohypophysis with a positive titer HCG-beta in the cerebrospinal fluid, CHILDS NERVOUS SYSTEM, 32(5), 901-904, 201605
    Link to Paper Search Results by DOI
  45. ★, Diffusion-weighted imaging and the apparent diffusion coefficient on 3T MR imaging in the differentiation of craniopharyngiomas and germ cell tumors, NEUROSURGICAL REVIEW, 39(2), 207-213, 201604
    Link to Paper Search Results by DOI
  46. ★, Clinical features and natural course of acromegaly in patients with discordance in the nadir GH level on the oral glucose test and the IGF-1 value at three months after adenomectomy, NEUROSURGICAL REVIEW, 39(2), 313-319, 2016
    Link to Paper Search Results by DOI
  47. Pituitary metastases: current practice in Japan, JOURNAL OF NEUROSURGERY, 123(4), 998-1007, 2015
    Link to Paper Search Results by DOI
  48. Treatment Strategy for Acromegaly, Jpn J Neurosurg, 24(8), 521-527, 2015
  49. ★, Postoperative fever specific to neuroendoscopic procedures, NEUROSURGICAL REVIEW, 37(1), 99-104, 201401
    Link to Paper Search Results by DOI
  50. ★, Pituitary adenomas in childhood and adolescence with a focus on intratumoral hemorrhage, PITUITARY, 17(1), 1-6, 2014
    Link to Paper Search Results by DOI
  51. Transsphenoidal surgical treatment of pituitary adenomas in patients aged 80 years or older, NEUROSURGICAL REVIEW, 37(2), 269-276, 2014
    Link to Paper Search Results by DOI
  52. ★, Impact of subclinical haemorrhage on the pituitary gland in patients with pituitary adenomas, CLINICAL ENDOCRINOLOGY, 80(5), 720-725, 2014
    Link to Paper Search Results by DOI
  53. A case of petrous apex cholesterol granuloma successfully treated with endoscopic endonasal surgery., Hiroshima J Med Sci, 63, 39-42, 2014
  54. ★, A craniopharyngioma with spontaneous involution of a gadolinium-enhanced region on magnetic resonance imaging, SURGICAL NEUROLOGY INTERNATIONAL, 5, 128, 2014
    Link to Paper Search Results by DOI
  55. Pharmacological Treatment for Pituitary Adenomas, Jpn J Neurosurg, 22(2), 101-108, 20130220
  56. ★, The arginine and GHRP-2 tests as alternatives to the insulin tolerance test for the diagnosis of adult GH deficiency in Japanese patients: A comparison, ENDOCRINE JOURNAL, 60(1), 97-105, 2013
    Link to Paper Search Results by DOI
  57. ★, A Rathke's cleft cyst located entirely in the anterior pituitary lobe, ACTA NEUROCHIRURGICA, 155(6), 1085-1086, 2013
    Link to Paper Search Results by DOI
  58. Severe growth hormone deficiency is rare in surgically-cured acromegalics, PITUITARY, 16(3), 326-332, 2013
    Link to Paper Search Results by DOI
  59. Growth Hormone Receptor Expression in Brain Tumors, Hiroshima Journal of Medical Sciences, 61(1), 1-6, 201203
  60. ★, Supra-diaphragmatic Pituitary Adenoma Removed Through the Trans-tuberculum Sellae Approach - Case Report, NEUROLOGIA MEDICO-CHIRURGICA, 52(2), 91-95, 2012
    Link to Paper Search Results by DOI
  61. Endonasal Endoscopic Transsphenoidal Surgery for theSellar or Parasellar Lesion, Japanese journal of neurosurgery, 20(0), 20110410
  62. ★, Post-operative hyponatremia in patients with pituitary adenoma: post-operative management with a uniform treatment protocol, ENDOCRINE JOURNAL, 58(5), 373-379, 2011
    Link to Paper Search Results by DOI
  63. ★, Masked hyperprolactinemia: Tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damage, JOURNAL OF CLINICAL NEUROSCIENCE, 18(12), 1651-1655, 2011
    Link to Paper Search Results by DOI
  64. Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas, EUROPEAN JOURNAL OF RADIOLOGY, 80(2), 412-417, 2011
    Link to Paper Search Results by DOI
  65. Gradual declination of IGF-1 over a year after transsphenoidal adenomectomy of GH producing pituitary adenomas, ENDOCRINE JOURNAL, 58(12), 1087-1091, 2011
    Link to Paper Search Results by DOI
  66. Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions, EUROPEAN JOURNAL OF RADIOLOGY, 74(3), 420-427, 2010
    Link to Paper Search Results by DOI
  67. The endoscopic surgery improves the outcome of the transsphenoidal surgery in the patients with functional pituitary adenomas, ENDOCRINE JOURNAL, 57, S524-S524, 2010
  68. Dissecting Aneurysm of the Posterior Inferior Cerebellar Artery : A Case Report, Japanese journal of neurosurgery, 14(6), 407-412, 20050620
  69. Occipital Sinus Pericranii associated with a Cerebellar Venous Angioma, JAPANESE JOURNAL OF NEUROSURGERY, 12(7), 496-501, 20030720

Invited Lecture, Oral Presentation, Poster Presentation

  1. Treatments of functional pituitary adenoma, 2023/05/21, With Invitation, Japanese
  2. 生理的過形成に伴い一過性両耳側半盲を繰り返す1例, 第27回　臨床内分泌代謝Update, 2017/11/25, Without Invitation, Japanese
  3. Influence of pseudo-capsular resection in non-functioning pituitary adenomas with a focus on postoperative pituitary functions, Joint neurosurgical convention 2016, The 7th international MT.bandai symposium for neuroscience, The 8th Pan-pacific neurosurgery congress, 2016/04/09, Without Invitation, English, Cambodia
  4. Masked hyperprolactinemia: Tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damage, Yasuyuki Kinoshita, 13th Pituitary Congress, 2013/06/13, Without Invitation

Awards

  1. 2013/11/02, Acromegaly Forum Incentive Award, Acromegaly Forum
  2. 2013/06/08, Kojinkai Award, Hiroshima University, Kojinkai, The arginine and GHRP-2 tests as alternatives to the insulin tolerance test for the diagnosis of adult GH deficiency in Japanese patients: A comparison

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2019/04, 2022/03
  2. KAKENHI, 2015, 2018

Social Activities

History as Peer Reviews of Academic Papers

  1. 2026, Journal of Neuro-Oncology, Others, 1
  2. 2026, Neuroradiology, Others, 1
  3. 2026, Acta Neurologica Belgica, Others, 1
  4. 2026, Pituitary, Others, 4
  5. 2026, Neurosurgical Review, Others, 4
  6. 2025, Journal of Clinical Neuroscience, Others, 1
  7. 2025, Neurosurgical Review, Others, 4
  8. 2025, Pituitary, Others, 2
  9. 2025, Journal of Neuro-Oncology, Others, 1
  10. 2025, Endocrine, Others, 2
  11. 2025, Endocrine Journal, Others, 1
  12. 2024, Neurosurgical Review, Others, 2
  13. 2024, World Neurosurgery, Others, 2
  14. 2024, Frontiers in Endocrinology, Others, 1
  15. 2024, Endocrine, Others, 1
  16. 2024, Pituitary, Others, 2
  17. 2024, Journal of Neuro-Oncology, Others, 3
  18. 2024, Cureus, Others, 1
  19. 2024, BMC Cancer, Others, 1
  20. 2023, World Neurosurgery, Others, 1
  21. 2023, Journal of Neuro-Oncology, Others, 2
  22. 2023, Neurosurgical Review, Others, 2
  23. 2023, Scientific Reports, Others, 3
  24. 2023, Endocrine Journal, Others, 1
  25. 2023, PLOS ONE, Others, 1
  26. 2022, Expert Review of Endocrinology & Metabolism, Others, 1
  27. 2022, Endocrinology, Diabetes & Metabolism, CASE REPORTS, Others, 2
  28. 2022, Neurosurgical Review, Others, 1
  29. 2021, Neurosurgical Review, Others, 1
  30. 2021, Neuroendocrinology, Others, 1
  31. 2020, Frontiers Neurology, Others, 1
  32. 2020, Neurosurgical Review, Others, 1
  33. 2020, Scientific Reports, Others, 1
  34. 2019, Endocrine Journal, Others, 1
  35. 2019, Endocrinology, Diabetes & Metabolism, CASE REPORTS, Others, 1