YASUYUKI KINOSHITA

Last Updated :2024/02/27

Affiliations, Positions
Hiroshima University Hospital(Medical), Associate Professor or Lecturer
E-mail
y-kinoshitahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • MD, PhD, Hiroshima University

Affiliated Academic Societies

  • The Japan Neurosurgical Society
  • The Japanese Congress of Neurological Surgeons
  • The japan Society for Hypothalamic and Pituitary Tumors
  • The Japan Endocrine Society
  • The Japanese Society for Neuroendoscopy
  • The Pituitary Society
  • The Japanese Congress of Brain Tumor Surgery
  • Conference on Neurosurgical Techniques and Tools
  • The Japan Brain Dock Society
  • The Japan Society for CNS Computed Imaging
  • Japan Society for Surgical Infection
  • The Japanese Headache Society

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, Year, Medical Neuroscience III
  2. 2023, Undergraduate Education, Intensive, Practice of Medicine I

Research Activities

Academic Papers

  1. Differences in invasiveness and recurrence rate among nonfunctioning pituitary neuroendocrine tumors depending on tumor subtype, Neurosurg Rev, 46(1), 317, 2023
  2. Long-Term Follow-Up Over 16 Years for Pituitary Hyperplasia Due to Primary Hypothyroidism With Positive Thyroid Stimulation Blocking Antibody: A Case Report, Cureus, 2023
  3. Characteristics and therapeutic strategies of brain and cranial radiation-induced sarcoma: analysis of 165 cases from our case experience and comprehensive review, Japanese Journal of Clinical Oncology, 2023
  4. Optic tract edema in craniopharyngioma as a predictor of BRAFV600E mutation presence, Japanese Journal of Clinical Oncology, 53(5), 378-385, 20230429
  5. Usefulness of critical flicker fusion frequency measurement and its laterality for evaluating compressive optic neuropathy due to pituitary neuroendocrine tumors, Neurosurgical Review, 46(1), 4, 202212
  6. ★, Natural course of Rathke's cleft cysts and risk factors for progression., Journal of Neurosurgery, 138(5), 1426-1432, 202209
  7. ★, Influence of growth hormone therapy on germinoma survivors, Pituitary, 25(6), 854-860, 202212
  8. ★, Predictive factors for recovery from adult growth hormone deficiency after transsphenoidal surgery for non-functioning pituitary adenoma, Journal of Neurosurgery, 25(1), 100-107, 2022
  9. ★, Isolated neurohypophysial sarcoidosis involving cavernous sinus mimicking malignant tumor, NMC Case Report Journal, 9, 31-35, 2022
  10. Intratumoral hemorrhage after endoscopic third ventriculostomy for obstructive hydrocephalus caused by brain tumors., World Neurosurgery, 158, e258-e264, 2022
  11. ★, Predictive factors of postoperative diabetes insipidus in 333 patients undergoing transsphenoidal surgery for non-functioning pituitary adenoma, Pituitary, 25(1), 100-107, 202202
  12. Metachronous double pituitary adenoma with altered transcriptional factor profile: a case report and literature review, NMC Case Report, 8(1), 657-663, 20211007
  13. ★, Pseudocapsular resection in elderly patients with non-functioning pituitary adenoma, Clinical Neurology and Neurosurgery, 210, 106997, 202111
  14. Clinical characteristics and thyroid hormone dynamics of thyrotropin-secreting pituitary adenomas at a single institution, Endocrine, 73(1), 151-159, 202107
  15. Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor, Eur J Radiol, 136, 109523, 202103
  16. Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature., World Neurosurgery, 134, e360-e371, 202002
  17. ★, Physiologic pituitary hyperplasia causing visual disturbance during adolescence, Journal of Clinical Neuroscience, 2019
  18. Sellar xanthogranuloma: a quest based on nine cases assessed with anterior pituitary provocation test., World Neurosurg, 2019
  19. ★, Nonfunctioning pituitary adenomas in elder patients, Journal of Clinical Neuroscience, 53, 127-131, 201807
  20. Factors Related to Frailty Associated with Clinical Deterioration After Meningioma Surgery in the Elderly., World neurosurgery, 201807
  21. Postoperative changes in metabolic parameters of patients with surgically controlled acromegaly: assessment of new stringent cure criteria, Neurol Med Chir (Tokyo), 58(4), 137, 201804
  22. Proton MRS detection of high lipid levels and low ADC is characteristics of germinoma., World Neurosurgery, 112, 84, 201804
  23. Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma., Neurosurg Focus, 44(4), E14, 201804
  24. ★, Pitfalls of a neuroendoscopic biopsy of intraventricular germ cell tumors, WORLD NEUROSURGERY, 106, 430-434, 201710
  25. Preoperative and Postoperative Pituitary Function in Patients with Tuberculum Sellae Meningioma -Based on Pituitary Provocation Tests., Neurol Med Chir (Tokyo), 57(10), 548-556, 201710
  26. Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma., Neurol Med Chir (Tokyo), 57(10), 521-533, 201710
  27. A Case of Intradural Retroclival Chordoma, No Shinkei Geka, 45, 623-627, 201707
  28. ★, Transsphenoidal posterior pituitary lobe biopsy in patients with neurohypophysial lesions., WORLD NEUROSURGERY, 99, 543-547, 201703
  29. Changes in quality of life in patients with acromegaly after surgical remission - A prospective study using SF-36 questionnaire., ENDOCRINE JOURNAL, 64(1), 27-38, 201701
  30. Effect of Gonadotropin and Adrenocorticotropic Hormone Secretion on Invasiveness of Clinically Nonfunctioning Pituitary Adenomas: A Cell Culture Study., WORLD NEUROSURGERY, 96, 578-584, 201612
  31. ★, The long-term recurrence of Rathke's cleft cysts as predicted by histology but not by surgical procedure, JOURNAL OF NEUROSURGERY, 125(4), 1002-1007, 201610
  32. Treatable glomerular hyperfiltration in patients with active acromegaly, EUROPEAN JOURNAL OF ENDOCRINOLOGY, 175(4), 325-333, 201610
  33. ★, The Surgical Side Effects of Pseudocapsular Resection in Nonfunctioning Pituitary Adenomas., WORLD NEUROSURGERY, 93, 430-435, 201609
  34. ★, Solitary Langerhans cell histiocytosis located in the neurohypophysis with a positive titer HCG-beta in the cerebrospinal fluid, CHILDS NERVOUS SYSTEM, 32(5), 901-904, 201605
  35. ★, Diffusion-weighted imaging and the apparent diffusion coefficient on 3T MR imaging in the differentiation of craniopharyngiomas and germ cell tumors, NEUROSURGICAL REVIEW, 39(2), 207-213, 201604
  36. ★, Clinical features and natural course of acromegaly in patients with discordance in the nadir GH level on the oral glucose test and the IGF-1 value at three months after adenomectomy, NEUROSURGICAL REVIEW, 39(2), 313-319, 2016
  37. Pituitary metastases: current practice in Japan, JOURNAL OF NEUROSURGERY, 123(4), 998-1007, 2015
  38. Treatment Strategy for Acromegaly, Jpn J Neurosurg, 24(8), 521-527, 2015
  39. ★, Postoperative fever specific to neuroendoscopic procedures, NEUROSURGICAL REVIEW, 37(1), 99-104, 201401
  40. ★, Pituitary adenomas in childhood and adolescence with a focus on intratumoral hemorrhage, PITUITARY, 17(1), 1-6, 2014
  41. Transsphenoidal surgical treatment of pituitary adenomas in patients aged 80 years or older, NEUROSURGICAL REVIEW, 37(2), 269-276, 2014
  42. ★, Impact of subclinical haemorrhage on the pituitary gland in patients with pituitary adenomas, CLINICAL ENDOCRINOLOGY, 80(5), 720-725, 2014
  43. A case of petrous apex cholesterol granuloma successfully treated with endoscopic endonasal surgery., Hiroshima J Med Sci, 63, 39-42, 2014
  44. ★, A craniopharyngioma with spontaneous involution of a gadolinium-enhanced region on magnetic resonance imaging, SURGICAL NEUROLOGY INTERNATIONAL, 5, 128, 2014
  45. Pharmacological Treatment for Pituitary Adenomas, Jpn J Neurosurg, 22(2), 101-108, 20130220
  46. ★, The arginine and GHRP-2 tests as alternatives to the insulin tolerance test for the diagnosis of adult GH deficiency in Japanese patients: A comparison, ENDOCRINE JOURNAL, 60(1), 97-105, 2013
  47. ★, A Rathke's cleft cyst located entirely in the anterior pituitary lobe, ACTA NEUROCHIRURGICA, 155(6), 1085-1086, 2013
  48. Severe growth hormone deficiency is rare in surgically-cured acromegalics, PITUITARY, 16(3), 326-332, 2013
  49. Growth Hormone Receptor Expression in Brain Tumors, Hiroshima Journal of Medical Sciences, 61(1), 1-6, 201203
  50. ★, Supra-diaphragmatic Pituitary Adenoma Removed Through the Trans-tuberculum Sellae Approach - Case Report, NEUROLOGIA MEDICO-CHIRURGICA, 52(2), 91-95, 2012
  51. Endonasal Endoscopic Transsphenoidal Surgery for theSellar or Parasellar Lesion, Japanese journal of neurosurgery, 20(0), 20110410
  52. ★, Post-operative hyponatremia in patients with pituitary adenoma: post-operative management with a uniform treatment protocol, ENDOCRINE JOURNAL, 58(5), 373-379, 2011
  53. ★, Masked hyperprolactinemia: Tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damage, JOURNAL OF CLINICAL NEUROSCIENCE, 18(12), 1651-1655, 2011
  54. Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas, EUROPEAN JOURNAL OF RADIOLOGY, 80(2), 412-417, 2011
  55. Gradual declination of IGF-1 over a year after transsphenoidal adenomectomy of GH producing pituitary adenomas, ENDOCRINE JOURNAL, 58(12), 1087-1091, 2011
  56. Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions, EUROPEAN JOURNAL OF RADIOLOGY, 74(3), 420-427, 2010
  57. The endoscopic surgery improves the outcome of the transsphenoidal surgery in the patients with functional pituitary adenomas, ENDOCRINE JOURNAL, 57, S524-S524, 2010
  58. Dissecting Aneurysm of the Posterior Inferior Cerebellar Artery : A Case Report, Japanese journal of neurosurgery, 14(6), 407-412, 20050620
  59. Occipital Sinus Pericranii associated with a Cerebellar Venous Angioma, JAPANESE JOURNAL OF NEUROSURGERY, 12(7), 496-501, 20030720

Invited Lecture, Oral Presentation, Poster Presentation

  1. Treatments of functional pituitary adenoma, 2023/05/21, With Invitation, Japanese
  2. 生理的過形成に伴い一過性両耳側半盲を繰り返す1例, 第27回 臨床内分泌代謝Update, 2017/11/25, Without Invitation, Japanese
  3. Influence of pseudo-capsular resection in non-functioning pituitary adenomas with a focus on postoperative pituitary functions, Joint neurosurgical convention 2016, The 7th international MT.bandai symposium for neuroscience, The 8th Pan-pacific neurosurgery congress, 2016/04/09, Without Invitation, English, Cambodia
  4. Masked hyperprolactinemia: Tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damage, Yasuyuki Kinoshita, 13th Pituitary Congress, 2013/06/13, Without Invitation

Awards

  1. 2013/11/02, Acromegaly Forum Incentive Award, Acromegaly Forum
  2. 2013/06/08, Kojinkai Award, Hiroshima University, Kojinkai, The arginine and GHRP-2 tests as alternatives to the insulin tolerance test for the diagnosis of adult GH deficiency in Japanese patients: A comparison

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2019/04, 2022/03
  2. KAKENHI, 2015, 2018

Social Activities

History as Peer Reviews of Academic Papers

  1. 2024, Endocrine, Others, 1
  2. 2024, Pituitary, Others, 1
  3. 2024, Journal of Neuro-Oncology, Others, 1
  4. 2024, Cureus, Others, 1
  5. 2024, BMC Cancer, Others, 1
  6. 2023, World Neurosurgery, Others, 1
  7. 2023, Journal of Neuro-Oncology, Others, 2
  8. 2023, Neurosurgical Review, Others, 2
  9. 2023, Scientific Reports, Others, 3
  10. 2023, Endocrine Journal, Others, 1
  11. 2023, PLOS ONE, Others, 1
  12. 2022, Expert Review of Endocrinology & Metabolism, Others, 1
  13. 2022, Endocrinology, Diabetes & Metabolism, CASE REPORTS, Others, 2
  14. 2022, Neurosurgical Review, Others, 1
  15. 2021, Neurosurgical Review, Others, 1
  16. 2021, Neuroendocrinology, Others, 1
  17. 2020, Frontiers Neurology, Others, 1
  18. 2020, Neurosurgical Review, Others, 1
  19. 2020, Scientific Reports, Others, 1
  20. 2019, Endocrine Journal, Others, 1
  21. 2019, Endocrinology, Diabetes & Metabolism, CASE REPORTS, Others, 1