KOJI IIDA

Last Updated :2025/07/07

Affiliations, Positions
Epilepsy Center, Professor
E-mail
iidakhiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Dr. of Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Neurosurgery

Research Keywords

  • magnetoencephalography
  • intractable epilepsy
  • epilepsy
  • pituitary adenoma
  • severe head injury
  • epilepsy surgery
  • Brain tumor

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Year, Medical Neuroscience III
  2. 2025, Undergraduate Education, Intensive, Practice for medical research
  3. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Epileptology
  5. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Epileptology
  6. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Epileptology
  7. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Epileptology
  8. 2025, Graduate Education (Master's Program) , First Semester, Further Study in Physiology and Pathology of Health

Research Activities

Academic Papers

  1. A Survey on the Awareness of Epilepsy Treatments in Community Pharmacies, Cureus, 202502
  2. Magnetoencephalographic detection of synchronized epileptic activity between the hippocampus and insular cortex, Epilepsy Behav Rep, 26, 100669-100669, 202404
    Link to Paper Search Results by DOI
  3. Incidence and prevalence of epilepsy in Japan: a retrospective analysis of insurance claims data of 9,864,278 insured persons, JOURNAL OF EPIDEMIOLOGY, 34(2), 70-75, 202402
    Link to Paper Search Results by DOI
  4. Paradoxical effects of levetiracetam in people with epilepsy with rhythmic epileptiform discharges, Epilepsy Behav, 143, 20230430
  5. Paradoxical effects of levetiracetam in people with epilepsy with rhythmic epileptiform discharges, EPILEPSY & BEHAVIOR, 143, 202306
    Link to Paper Search Results by DOI
  6. Hippocampal volumetry to determine the resection side in patients with intractable non-lesional bilateral temporal lobe epilepsy, SCIENTIFIC REPORTS, 13(1), 20230223
    Link to Paper Search Results by DOI
  7. Magnetoencephalographic spikes with small spikes on simultaneous electroencephalography have high spatial clustering in temporal lobe epilepsy, EPILEPSY RESEARCH, 192, 202305
    Link to Paper Search Results by DOI
  8. Gradient magnetic-oscillation topography depicts high frequency oscillations on brain surface related to epileptic focus in intractable epilepsy with lesions, Hiroshima J Med Sci, 72, 11-19, 202306
  9. Primary somatosensory cortex sensitivity may increase upon completion of a motor task, NEUROSCIENCE LETTERS, 801, 20230328
    Link to Paper Search Results by DOI
  10. Immediate and 6-month seizure outcomes following first and second SARS-CoV2 mRN vaccinations: A multicenter study with a nationwide survey, Epilepsy Behav, 139, 109070, 2023
  11. A longitudinal seizure outcome following the COVID-19 pandemic in 2020 and 2021: Transient exacerbation or sustainable mitigation., J Neurol Sci, 434, 20220315
  12. Impact of COVID-19 pandeimc on epilepsy care in Japan: A national-lebel multicenter retrospective cohort study, Epilepsia Open, 28(7), 431-441, 2022
  13. Prevalence of immune-related adverse events and anti-tumor efficacy following immune checkpoint inhibitor therapy in Japanese patients with various solid tumors, BMC CANCER, 22(1), 20221129
    Link to Paper Search Results by DOI
  14. Characterization of cortical activity in juvenile myoclonic epilepsy by gradient magnetic field topography, CLINICAL NEUROPHYSIOLOGY, 141, 62-74, 202209
    Link to Paper Search Results by DOI
  15. Neural sources of vagus nerve stimulation-induced slow cortical potentials, Neuromodulation, 20220215
    Link to Paper Search Results by DOI
  16. Risk factors for psychological distress in electroencephalography technicians during the COVID-19 pandemic: A national-leverl corss-sectional survey in Japan, Epilepsy Behav, 125, 108361, 202112
    Link to Paper Search Results by DOI
  17. Overcomig the challenges of epilepsy in Nepal – From grassroots to advanced level, Annapuruna Journal of Health Sciences (AJHS), 1, 55-57, 20210208
  18. Seizure deterioration with increased levetiracetam blood concentration during the postpartum period in refractory temporal lobe epilepsy, Intern Med, DOI: 10.2169/internalmedicine.8173-21, 2021
  19. Interpersonal communication skills related to seizure outcomes in pediatric patients with vagus nerve stimulation, Interdiscip Neurosurg, 24, 101080, 2021
  20. Initiating an epilepsy surgery program with limited resources in Indonesia, SCIENTIFIC REPORTS, 11(1), 20210303
    Link to Paper Search Results by DOI
  21. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area, EPILEPSY & BEHAVIOR, 117, 202104
    Link to Paper Search Results by DOI
  22. ★, Comparison of seizure outcomes and ADL recovery period after total or anterior corpus callosotomy in adolescent and young adults with drop attacks and severe mental retardation, Epilepsy Res, 176, 106706, 2021
  23. Comparison of seizure outcomes and ADL recovery period after total or anterior corpus callosotomy in adolescent and young adults with drop attacks and severe mental retardation, EPILEPSY RESEARCH, 176, 202110
    Link to Paper Search Results by DOI
  24. Efficacy and safety of perampanel monotherapy in patients with focal-onset seizures with newly diagnosed epilepsy or recurrence of epilepsy after a period of remission: the open-label Study 342 (FREEDOM study), Epilepsia Open, 5, 274-284, 2020
  25. Surgery for radiologically normal-appearing temporal lobe epilepsy in a center with limited resources., Scientific Reports, 10, 2020
  26. Surgery for Radiologically Normal-Appearing Temporal Lobe Epilepsy in a Centre with Limited Resources, SCIENTIFIC REPORTS, 10(1), 20200518
    Link to Paper Search Results by DOI
  27. Secondary epileptogenesis on gradient magnetic-field topography correlates with seizure outcomes after vagus nerve stimulation, Epilepsy Res, 167, 106463, 2020
  28. Preoperative sensory aura predicts risk for seizure in temporal lobe epilepsy surgery, EPILEPSY & BEHAVIOR, 111, 202010
    Link to Paper Search Results by DOI
  29. Comparative Evaluation of Angioscopy and Intravascular Ultrasound for Assessing Plaque Protrusion During Carotid Artery Stenting Procedures, WORLD NEUROSURGERY, 125, E448-E455, 201905
    Link to Paper Search Results by DOI
  30. Anti-seizure effect and neuronal activity change in the genetic-epileptic model rat with acute and chronic vagus nerve stimulation., Epilepsy Res, 2019
  31. Preservation of memory despite unresected contralateral hippocampal volume loss after resection of hippocampal sclerosis in seizure free patients, World Neurosurgery, 2019
  32. Hemipherotomy for drug-resistant hemiepheric epilepsy in Indonesian population., Epilepsy Behav Rep, 20191105
  33. Application of Rubber Band with Hooks on Both Ends for Vagus Nerve Stimulator Implantation, WORLD NEUROSURGERY, 111, 258-260, 201803
    Link to Paper Search Results by DOI
  34. Long-term outcomes of epilepsy surgery in 85 pediatric patients followed up for over 10 years: a retrospective survey, JOURNAL OF NEUROSURGERY-PEDIATRICS, 19(5), 606-615, 201705
    Link to Paper Search Results by DOI
  35. Stereoelectroencephalography: Indication and Efficacy, NEUROLOGIA MEDICO-CHIRURGICA, 57(8), 375-385, 201708
    Link to Paper Search Results by DOI
  36. We could predict good responders to vagus nerve stimulation: A surrogate marker by slow cortical potential shift., Clin Neurophysiol, 128, 1583-1589, 2017
  37. Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma, NEUROLOGIA MEDICO-CHIRURGICA, 57(10), 521-533, 201710
    Link to Paper Search Results by DOI
  38. We could predict good responders to vagus nerve stimulation: A surrogate marker by slow cortical potential shift, CLINICAL NEUROPHYSIOLOGY, 128(9), 1583-1589, 201709
    Link to Paper Search Results by DOI
  39. Magnetoencephalography using gradient magnetic field topography (GMFT) can predict successful anterior corpus callosotomy in patients with drop attacks, CLINICAL NEUROPHYSIOLOGY, 127(1), 221-229, 201601
    Link to Paper Search Results by DOI
  40. Combined surgical intervention with vagus nerve stimulation following corpus callosotomy in patients with Lennox-Gastaut syndrome, ACTA NEUROCHIRURGICA, 158(5), 1005-1012, 201605
    Link to Paper Search Results by DOI
  41. Novel Software for Performing Leksell Stereotactic Surgery without the Use of Printing Films: Technical Note, NEUROLOGIA MEDICO-CHIRURGICA, 56(4), 193-197, 2016
    Link to Paper Search Results by DOI
  42. Determination of hemispheric language dominance using functional magnetic resonance imaging and the Shiritori (Japanese word chain) task in patients with epilepsy: Comparison with the Wada test, EPILEPSY RESEARCH, 124, 16-22, 201608
    Link to Paper Search Results by DOI
  43. Characteristic expression of p57/Kip2 in balloon cells in focal cortical dysplasia, Neuropathology, 35(5), 401-409, 201510
    Link to Paper Search Results by DOI
  44. Diagnostic performance of positron emission tomography for presurgical evaluation in patients with non-lesional intractable partial epilepsy: comparison between 18F-FDG, 11C-flumazenil and 11C-flumazenil binding potential imaging by using statistical imaging analysis., Hiroshima J Med Sci, 2015
  45. Electrocorticographic-Histopathologic Correlations Implying Epileptogenicity of Dysembryoplastic Neuroepithelial Tumor, Neurol Med Chir, 53(10), 676-687, 201310
    Link to Paper Search Results by DOI
  46. Successful treatment of mesial temporal lobe epilepsy with bilateral hippocampal atrophy and false temporal scalp ictal onset: A case repor, Hiroshima J Med Sci, 61, 37-41, 2012
  47. Late recurrence of intractable epilepsy associated with MRI-occult pilocytic astrocytoma in the temporal lobe nine years after initial removal: A case report., Hiroshima J Med Sci, 60, 63-68, 2011
  48. Gradient magnetic-field topography reflecting cortical activities of neocortical epilepsy spikes, EPILEPSY RESEARCH, 90(1-2), 121-131, 201006
    Link to Paper Search Results by DOI
  49. Development of a freeware for analysis of neuromagnetic epileptic discharges., Hiroshima J Med Sci, 59, 21-25, 2010
  50. P16-1 Quasi gradient magnetic field topography compatible with 32/64bit MS-Windows Vista or Mac OSZ 10.6, Clin Neurphysiol, 2010
  51. LC method for the determination of meropenen in cerebrospinal fluid: Application to therapeutic drug monitoring, Chromatographia, 69, 1031-1034, 2009
  52. The pharmacokinetics and pharmacodynamics exposure of meropenem in the cerebrospinal fluid of neurosurgical patients., Journal of Chemotherapy, 20(5), 615-621, 20081001
  53. Abnormality of Ca2+ channels in CA3 pyramidal neurons of Noda Epileptic Rats (NERs), Epilepsia, 39, 55-55, 2008
  54. Interhemispheric reorganization of language in children with medically intractable epilepsy of the left hemisphere, J Int Neuropsychol Soc, 13, 505-516, 20070101
  55. Zygomatic osteotomy for resection of cavernous angioma in dominant hemispheric temporal lobe, Hiroshima Journal of Medical Science, 55, 39-43, 20060331
  56. Natural course of incidentally found nonfunctioning pituitary adenoma, with special reference to pituitary apoplexy during follow-up examination., J Neurosurg, 104(6), 884-891, 20060601
  57. Preoperative simulation of intracerebral epileptiform discharges: synthetic aperture magnetometry virtual sensor analysis of interictal magnetoencephalography data, J Neurosurg, 105, 41-49, 20060331
  58. Efficacy of steroid for cerebral swelling and seizures during subdural grid EEG recording in children., Epilepsia, 47, 176-180, 20060331
  59. ★, 14.Characterizing Magnetic Spike Sources by using Magnetoencephalography-guided Neuronavigation in Pediatric Epilepsy Surgery, Journal of Neurosurg (Pediatrics 2), 102, 187-196, 20051231
  60. Neurophysiological findings of neuronal migration disorders: Intrinsic epileptogenicity of focal cortical dysplasia on electroencephalography, electrocorticography, and magnetoencephalograophy, J Child Neurol, 20, 357-363, 20050331
  61. Cortical resection with electrocorticography for intractable porencehpaly-related partial epilepsy, Epilepsia, 46, 76-83, 20050331
  62. Startle-induced seizures associated with infantile hemiplegia: Implication of the supplementary motor area, Epilepsy Disord, 7, 49-52, 20050331
  63. Hypothalamic hamartoma, Neurologia Medico Chirurgica (Tokyo), 45, 225-236, 20050331
  64. Three-dimensionally reconstructed magnetic source imaging and neuronavigation in pediatric epilepsy: Technical note., Neurosurgery, 55, 1244-1248, 20040331
  65. Dipole source localization of epileptic discharges in EEG and MEG, International Congress Series, 1270, 56-60, 20040331
  66. Anatomy and techniques for epilepsy surgery, NEUROLOGICAL SURGERY, 32(12), 1215-1227, 200412
    Link to Paper Search Results by DOI
  67. Hyperemia prior to acute brain swelling during rewarming of patients who have been treated with moderate hypothermia for severe head injuries, J Neurosurg, 98, 793-799, 2003
  68. Mortality in 154 surgically treated patients with acromegaly--a 10-year follow-up survey, Endocr J, 50, 163-172, 2003
  69. Epileptic seizure induced by N-acetyl-L-aspartate in rats: in vivo and in vitro studies., Brain Research, 861, 143-150, 20000401
  70. Induction of convulsive seizures by acoustic priming in a new genetically defined model of epilepsy (Noda epileptic rat: NER),, Epilepsy Research, 30(2), 115-126, 19980401

Publications such as books

  1. 2015/01, MRI-negative Epilepsy: Evaluation and Surgical Management, MEG and magnetic source imaging in MRI-negative refractory partial epilepsy, Cambridge University Press, 2015, 1, Scholarly Book, Joint work, 47-55
  2. 2012/01, Neurosurgical treatment of vascular diseases of the CNS ( central nervous system), Therapeutic hypothermia for ischemic and hemorrhagic stroke, Dilivros, 2012, 1, Scholarly Book, Joint work, 423-431
  3. 2012/01, Neurosurgical treatment of vascular diseases of the CNS ( central nervous system), Epilepsy surgery and cerebral vascular malformations, Dilivros, 2012, 1, Scholarly Book, Joint work, 英語, 151-159

Invited Lecture, Oral Presentation, Poster Presentation

  1. How to interpret EEG, Iida K, 9th Himalayan Epilepsy Workshop, 2024/05/28, With Invitation, English, Neurofoundation Nepal (NFN), Hirohisma University Hospital, JICA, Kathmandu, Nepal
  2. Epilepsy treatment -Clinical significance of seizure semiology/neuroimaging and surgical strategy, Iida K, 8th Himalayan Epilepsy Workshop (CME seminar), 2024/05/24, With Invitation, English, Neurofoundation Nepal (NFN), Hiroshima University Hospital, JICA, Chitwan, Nepal
  3. Introduction of robot-assisted stereo-electroencephalography (SEEG): As a new technique for intractable epilepsy patients in Japan, Iida K, 28th Annual scientific meeting of Indonesian Neurosurgical Society (INS), 2024/06/09, With Invitation, English, 28th Annual scientific meeting of Indonesian Neurosurgical Society (INS), Jakarta, Indonesiia
  4. Epilepsy treatment -Clinical significance of seizure semiology/neuroimaging and surgical strategy, Iida K, 7th Himalayan Epilepsy Workshop (CME seminar), 2023/08/12, With Invitation, Japanese
  5. Phase 2 Study of Intravenous Perampanel in Japanese Epilepsy Patients -Safety Evaluation of Alternative to Oral Dosing-, Iida K, Hanaya R, Yamamuro S, Yamaguchi K, Onishi K, Ngo LY, Inoue Y., The 51st Annual Meeting of Japanese Association of Acute Medicine, 2023/11/29, Without Invitation, Japanese, The 51st Annual Meeting of Japanese Association of Acute Medicine, Tokyo
  6. Customizing withdrawal of antiepileptic drugs in pre-monitroing admission to capture seizures during limited video-EEG monitoring, Kagawa K, Iida K, Ochi A, Baba S, Makajima M, Iimura Y, Hashizume A, Katagiri M, Kurisu K, Otsubo H, 70th AES Annual Meeting 2016, 2016/12/03, Without Invitation, English
  7. Therapeutic advance in refractory epilepsies: Epileptogenic localization and surgical intervention., Annapurna Epilepsy CME program, 2016/04/27, With Invitation, English, Annapurna Epilepsy CME program
  8. Role of epilepsy center as a central insititute of medical care for epilepsy, Chitwan Medical College CME program, 2016/04/24, With Invitation, English, Chitwan Medical College, Nepal
  9. Intra/extra-operative funcitional mapping for cerebral tumor resection adjacent to eloquent cortex., 2008, With Invitation
  10. Callosotomy and other palliative procedures, 2nd Himalayan epilepsy workshop, 2008, With Invitation, English
  11. Invasive evaluation for epilepsy surgery, 2nd Himalayan epilepsy workshop, 2008, With Invitation, English
  12. Extra-temporal lobe epilepsy –case presentations-, 2007, With Invitation, English
  13. Mesial temporal lobe epilepsy –case presentations-., 1st Himalayan epilepsy workshop., 2007, With Invitation, English
  14. Surgical candidates for intractable epilepsy. -Seizure semiology, EEG findings, and surgical strategy in mesial TLE -, 2005, With Invitation, English
  15. An orderly approach to the electroencephalogram (EEG)　- EEG analysis as presurgical evaluation., CME supported by Nepal epilepsy society, 2005, With Invitation, English
  16. Treatment of status epilepticus in Hiroshima University. Indonesian Neurological Association, Course on Epilepsy and surgical treatment, 2000, With Invitation, English