SHUICHIRO NESHIGE

Last Updated :2025/06/12

Affiliations, Positions
Hiroshima University Hospital(Medical), Assistant Professor
E-mail
s-neshigehiroshima-u.ac.jp
Self-introduction
Neurology specialized in clinical neurophysiology and epilepsy is of my interest.

Basic Information

Major Professional Backgrounds

  • 2008/04/01, 2010/03/31, Hiroshima University, Hospital, Clinical Resident
  • 2010/04, 2012/03, National Hospital Organization Kure Medical Center, Clinical Fellow
  • 2012/04, 2014/03, Ota Memorial Hospital, Clinical Fellow
  • 2014/04/01, 2015/03/31, Hiroshima University, Hospital, Clinical Fellow
  • 2018/09, 2018/12, Kyoto University Hospital, Clinical Fellow
  • 2019/01/01, Hiroshima University, Hospital, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical & Health Sciences , Japan, 2014/04, 2018/08
  • Oita University, Japan, 2001/04, 2008/03

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Neurology

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Intensive, Introduction to clinical clerkship
  2. 2025, Undergraduate Education, Year, Medical Neuroscience III
  3. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2025, Undergraduate Education, Intensive, Practice of Medicine II

Research Activities

Academic Papers

  1. Early initiation of intravenous cyclophosphamide and one-year outcome in super-refractory cryptogenic-new onset refractory status epilepticus, EPILEPSIA OPEN, 10(1), 307-313, 202502
  2. Screening of toxic-metabolic encephalopathy with and without epileptic seizure with density spectral array, JOURNAL OF THE NEUROLOGICAL SCIENCES, 472, 20250515
  3. Alpha-band activity in density spectral array predictive for neurological outcome in patients with hypoxic-ischemic encephalopathy, CLINICAL NEUROLOGY AND NEUROSURGERY, 250, 202503
  4. ★, Presenteeism in people with previous and current epilepsy: Determinants and psychosocial associations, SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 125, 16-22, 202502
  5. Diffusion-weighted imaging findings predictive of postoperative recurrence of chronic subdural hematoma, JOURNAL OF THE NEUROLOGICAL SCIENCES, 467, 20241215
  6. ★, Interictal head-turning sign in patients with idiopathic generalized epilepsy during initial medical interview: A matched multicenter study, EPILEPSY & BEHAVIOR, 160, 202411
  7. Vagus nerve size determined via ultrasonography is associated with white matter lesions in patients with vascular risk factors, JOURNAL OF ULTRASOUND, 27(3), 723-732, 202409
  8. Clinical manifestations and outcomes associated with a high 2HELPS2B score in patients with acute impaired consciousness, JOURNAL OF THE NEUROLOGICAL SCIENCES, 465, 20241015
  9. Redefined giant somatosensory evoked potentials: Evoked epileptic complexes of excitatory and inhibitory components, CLINICAL NEUROPHYSIOLOGY, 164, 119-129, 202408
  10. Emergency medical service response for cases of stroke-suspected seizure: A population-based study, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 33(6), 202406
  11. Irregular Tremulous Movements and Infrequent Seizures: A Clinical-Electrophysiological Diagnosis of Benign Adult Familial Myoclonus Epilepsy, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240317
  12. Chronic Visual Abnormality in an Elderly Patient With Temporal Lobe Epilepsy, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240322
  13. An Early Neurological Indicator of Immune Effector Cell-Associated Neurotoxicity Syndrome, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240330
  14. Specific consistency score for rational selection of epilepsy resection surgery candidates, EPILEPSIA, 65(5), 1322-1332, 202405
  15. Therapeutic Time Window With DWI-ADC (Diffusion-Weighted Imaging-Apparent Diffusion Coefficient) Match and Periodic Discharges for Status Epilepticus, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(2), 20240207
  16. Density spectrum array and difficult to diagnose seizure activity, QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 116(11), 947-948, 202311
  17. ★, On-scene time delays for epileptic seizures in developed community-based integrated care system regions, EPILEPSY & BEHAVIOR, 151, 202402
  18. Attacks With Urinary Incontinence Without Convulsions: Complete Atrioventricular Block Mimicking an Epileptic Seizure, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(11), 20231128
  19. Exacerbation of Repetitive Falls Due to Atonic Seizures Following Perampanel Administration, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(6), 20230622
  20. On-scene time delays for epileptic seizures in emergencies during a social pandemic: A population-based study, EPILEPSY & BEHAVIOR, 142, 202305
  21. Paradoxical effects of levetiracetam in people with epilepsy with rhythmic epileptiform discharges, EPILEPSY & BEHAVIOR, 143, 202306
  22. Clinical diagnostic criteria of benign adult familial myoclonus epilepsy type 1 are highly concordant with genetic testing, NEUROLOGY AND CLINICAL NEUROSCIENCE, 11(3), 140-145, 202305
  23. ★, Immediate and 6-month seizure outcomes following first and second SARS-CoV2 mRNA vaccinations: A multicenter study with a nationwide survey, EPILEPSY & BEHAVIOR, 139, 202302
  24. Unique, Not Psychogenic Movements: Painful Leg and Moving Toes Syndrome, CUREUS JOURNAL OF MEDICAL SCIENCE, 14(9), 20220914
  25. A longitudinal seizure outcome following the COVID-19 pandemic in 2020 and 2021: Transient exacerbation or sustainable mitigation, JOURNAL OF THE NEUROLOGICAL SCIENCES, 434, 20220315
  26. Absence of an Autonomic Sign Assists in the Diagnosis of Extratemporal Lobe Epilepsy Manifesting Generalized Convulsion with Retained Awareness, Internal Medicine, 58(8), 1151-1155, 2019
  27. Low-dose perampanel improves refractory cortical myoclonus by the dispersed and suppressed paroxysmal depolarization shifts in the sensorimotor cortex, CLINICAL NEUROPHYSIOLOGY, 130(10), 1804-1812, 201910
  28. ★, A score to map the lateral nonprimary motor area: Multispectrum intrinsic brain activity versus cortical stimulation, EPILEPSIA, 60(11), 2294-2305, 201911
  29. Efficacy of wide-band electrocorticography on mapping of the primary seonsory-motor area compared with electrical cortical stimulation, Journal of the Neurological Sciences, 381, 86
  30. ★, A rational, multispectral mapping algorithm for primary motor cortex: A primary step before cortical stimulation, EPILEPSIA, 60, 547-559, 201903
  31. ★, Multi-component intrinsic brain activities as a safe, alternative to cortical stimulation for sensori-motor mapping in neurosurgery, Clinical Neurophysiology, 129(9), 2038-2048, 201809
  32. Shifting laxative dosing schedule to an earlier time improves refractory constipation in Parkinson's disease: a case series, Neurology and Clinical Neuroscience, 6(6), 182-184, 2018
  33. Elderly woman with exaggerated startle reflex and unconscious drop attack, Neurology and Clinical Neuroscience, 4(4), 156-158, 2016
  34. Seizures after intracerebral hemorrhage; risk factor, recurrence, efficacy of antiepileptic drug, Journal of the neurological sciences, 359(1-2), 318-322, 2015
  35. Ischemic stroke mortality is more strongly associated with anemia on admission than with underweight status, Journal of Stroke and Cerebrovascular Diseases, 26(6), 1369-1347
  36. Ability of the ankle brachial index and brachial-ankle pulse wave velocity to predict the 3-month outcome in patients with non-cardioembolic stroke, Japan Atherosclerosis Society, 38901
  37. Brain natriuretic peptide and particular left ventricle segment asynergy associated with cardioembolic stroke from old myocardial infarction, Journal of Stroke and Cerebrovascular Diseases, 25(5), 1165-1171
  38. ABI and baPWV Are Independent Predictive Factors for a Clinical Outcome in Acute Non-Cardioembolic Stroke: P061, Cerebrovascular Diseases, 40
  39. Acute ischemic stroke associated with nephrotic syndrome: Incidence and significance—Retrospective cohort study, eNeurologicalSci, 1(3-4), 47-50
  40. Risk Factors for Stroke/Prognosis Acute ischemic stroke associated with nephrotic syndrome: Prevalence and significance, International Journal of Stroke, 10
  41. Cerebrovascular Occlusive Disease Progression of responsible intracranial artery stenosis prior to ischemic stroke onset–Fukuyama Intracranial Artery Stenosis (FICAS) Study–, International Journal of Stroke, 9
  42. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area, EPILEPSY & BEHAVIOR, 117, 202104
  43. Rapid ping-pong eye deviation following a recovery from carbon dioxide narcosis, BMJ CASE REPORTS, 14(3), 202103
  44. Influence of current and previous smoking on current phenotype in Parkinson's disease, JOURNAL OF THE NEUROLOGICAL SCIENCES, 427, 20210815
  45. Psychiatric non-epileptic seizure: diagnostic utility of density spectral array, BMJ case reports, 14, e241015, 2021
  46. A Biomarker for Benign Adult Familial Myoclonus Epilepsy: High-Frequency Activities in Giant Somatosensory Evoked Potentials, Movement Disorders, 2021
  47. Emotional Facial Paresis in Temporal Lobe Epilepsy, Internal Medicine, 60(16), 2021
  48. Extreme delta brush in anti- NMDAR encephalitis: Mimics and chameleons, Epilepsia Open, 6, 443-446, 2021
  49. Efficacy of Lacosamide in a Patient with Refractory Generalized Epilepsy Based on Video Electroencephalography, Internal Medicine, 2021
  50. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study, Anaesthesia, 76(6), 748-758, 2021
  51. Marked response to perampanel: A decade-long course of giant somatosensory evokedpotentials in Unverricht-Lundborg disease, Clinical Neurophysiology, 132, 2329-2331, 2021
  52. ★, A Role of Aging in the Progression of Cortical Excitability in Benign Adult Familial Myoclonus Epilepsy type 1 Patients, Movement Disorders, 2021
  53. Nationwide online EEG education during coronavirus disease 2019 pandemic, Clinical Neurophysiology, 2021
  54. A case of repetitive seizures following immune checkpoint inhibitor therapy as a feature of autoimmune encephalitis, Epileptic Disorders, 2021
  55. Needs of Epilepsy Care from Inter-hospital Network System of Epilepsy: Sample Survey of the Epilepsy Clinic in Kyoto University Hospital, Journal of the Japan Epilepsy Society, 35(3), 2018

Invited Lecture, Oral Presentation, Poster Presentation

  1. A rational, multi-spectrum mapping algorithm for primary motor cortex: a primary step before cortical stimulation, Shuichiro Neshige, Japanese Neurology Society Conference 2019, Without Invitation, Japanese, published
  2. Medical education during the COVID-19 pandemic in Japan: EEG-Webinar using an online application, Shuichiro Neshige, Without Invitation, English, published
  3. Socio-economic and psychological impact on epilepsy outside of the nation-wide COVID-19 pandemic area in Japan, Shuichiro Neshige, Japan Epilepsy Society Conference 2021, Without Invitation, English, published
  4. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area in Japan, Shuichiro Neshige, 13th Asian & Oceanian Epilepsy Congress, Without Invitation, English, published

Awards

  1. 44th JUHN AND MARY WADA awrd, Japanese Epilepsy Society
  2. 2018, Japanese Epilepsy Society Sponsored Award, Japanese Epilepsy Society
  3. 2018, Japanese Epilepsy Society,Hans Berger Award, Japanese Epilepsy Society

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2020, 2022