SHUICHIRO NESHIGE

Last Updated :2025/07/07

Affiliations, Positions
Hiroshima University Hospital, Assistant Professor
E-mail
s-neshigehiroshima-u.ac.jp
Self-introduction
Neurology specialized in clinical neurophysiology and epilepsy is of my interest.

Basic Information

Major Professional Backgrounds

  • 2008/04/01, 2010/03/31, Hiroshima University, Hospital, Clinical Resident
  • 2010/04, 2012/03, National Hospital Organization Kure Medical Center, Clinical Fellow
  • 2012/04, 2014/03, Ota Memorial Hospital, Clinical Fellow
  • 2014/04/01, 2015/03/31, Hiroshima University, Hospital, Clinical Fellow
  • 2018/09, 2018/12, Kyoto University Hospital, Clinical Fellow
  • 2019/01/01, Hiroshima University, Hospital, Assistant Professor

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical & Health Sciences , Japan, 2014/04, 2018/08
  • Oita University, Japan, 2001/04, 2008/03

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Neurology

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Intensive, Introduction to clinical clerkship
  2. 2025, Undergraduate Education, Year, Medical Neuroscience III
  3. 2025, Undergraduate Education, Intensive, Practice of Medicine I
  4. 2025, Undergraduate Education, Intensive, Practice of Medicine II

Research Activities

Academic Papers

  1. Early initiation of intravenous cyclophosphamide and one-year outcome in super-refractory cryptogenic-new onset refractory status epilepticus, EPILEPSIA OPEN, 10(1), 307-313, 202502
    Link to Paper Search Results by DOI
  2. Screening of toxic-metabolic encephalopathy with and without epileptic seizure with density spectral array, JOURNAL OF THE NEUROLOGICAL SCIENCES, 472, 20250515
    Link to Paper Search Results by DOI
  3. Alpha-band activity in density spectral array predictive for neurological outcome in patients with hypoxic-ischemic encephalopathy, CLINICAL NEUROLOGY AND NEUROSURGERY, 250, 202503
    Link to Paper Search Results by DOI
  4. ★, Presenteeism in people with previous and current epilepsy: Determinants and psychosocial associations, SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 125, 16-22, 202502
    Link to Paper Search Results by DOI
  5. Diffusion-weighted imaging findings predictive of postoperative recurrence of chronic subdural hematoma, JOURNAL OF THE NEUROLOGICAL SCIENCES, 467, 20241215
    Link to Paper Search Results by DOI
  6. ★, Interictal head-turning sign in patients with idiopathic generalized epilepsy during initial medical interview: A matched multicenter study, EPILEPSY & BEHAVIOR, 160, 202411
    Link to Paper Search Results by DOI
  7. Vagus nerve size determined via ultrasonography is associated with white matter lesions in patients with vascular risk factors, JOURNAL OF ULTRASOUND, 27(3), 723-732, 202409
    Link to Paper Search Results by DOI
  8. Clinical manifestations and outcomes associated with a high 2HELPS2B score in patients with acute impaired consciousness, JOURNAL OF THE NEUROLOGICAL SCIENCES, 465, 20241015
    Link to Paper Search Results by DOI
  9. Redefined giant somatosensory evoked potentials: Evoked epileptic complexes of excitatory and inhibitory components, CLINICAL NEUROPHYSIOLOGY, 164, 119-129, 202408
    Link to Paper Search Results by DOI
  10. Emergency medical service response for cases of stroke-suspected seizure: A population-based study, JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 33(6), 202406
    Link to Paper Search Results by DOI
  11. Irregular Tremulous Movements and Infrequent Seizures: A Clinical-Electrophysiological Diagnosis of Benign Adult Familial Myoclonus Epilepsy, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240317
    Link to Paper Search Results by DOI
  12. Chronic Visual Abnormality in an Elderly Patient With Temporal Lobe Epilepsy, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240322
    Link to Paper Search Results by DOI
  13. An Early Neurological Indicator of Immune Effector Cell-Associated Neurotoxicity Syndrome, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(3), 20240330
    Link to Paper Search Results by DOI
  14. Specific consistency score for rational selection of epilepsy resection surgery candidates, EPILEPSIA, 65(5), 1322-1332, 202405
    Link to Paper Search Results by DOI
  15. Therapeutic Time Window With DWI-ADC (Diffusion-Weighted Imaging-Apparent Diffusion Coefficient) Match and Periodic Discharges for Status Epilepticus, CUREUS JOURNAL OF MEDICAL SCIENCE, 16(2), 20240207
    Link to Paper Search Results by DOI
  16. Density spectrum array and difficult to diagnose seizure activity, QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 116(11), 947-948, 202311
    Link to Paper Search Results by DOI
  17. ★, On-scene time delays for epileptic seizures in developed community-based integrated care system regions, EPILEPSY & BEHAVIOR, 151, 202402
    Link to Paper Search Results by DOI
  18. Attacks With Urinary Incontinence Without Convulsions: Complete Atrioventricular Block Mimicking an Epileptic Seizure, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(11), 20231128
    Link to Paper Search Results by DOI
  19. Exacerbation of Repetitive Falls Due to Atonic Seizures Following Perampanel Administration, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(6), 20230622
    Link to Paper Search Results by DOI
  20. Reversible Brain Atrophy in Cryptogenic New-onset Refractory Status Epilepticus, INTERNAL MEDICINE, 62(12), 1835-1842, 2023
    Link to Paper Search Results by DOI
  21. On-scene time delays for epileptic seizures in emergencies during a social pandemic: A population-based study, EPILEPSY & BEHAVIOR, 142, 202305
    Link to Paper Search Results by DOI
  22. Paradoxical effects of levetiracetam in people with epilepsy with rhythmic epileptiform discharges, EPILEPSY & BEHAVIOR, 143, 202306
    Link to Paper Search Results by DOI
  23. Clinical diagnostic criteria of benign adult familial myoclonus epilepsy type 1 are highly concordant with genetic testing, NEUROLOGY AND CLINICAL NEUROSCIENCE, 11(3), 140-145, 202305
    Link to Paper Search Results by DOI
  24. ★, Immediate and 6-month seizure outcomes following first and second SARS-CoV2 mRNA vaccinations: A multicenter study with a nationwide survey, EPILEPSY & BEHAVIOR, 139, 202302
    Link to Paper Search Results by DOI
  25. ★, Are patients with Parkinson's disease at a lower risk of catching the common cold? Propensity score matching, PARKINSONISM & RELATED DISORDERS, 106, 202301
    Link to Paper Search Results by DOI
  26. Unique, Not Psychogenic Movements: Painful Leg and Moving Toes Syndrome, CUREUS JOURNAL OF MEDICAL SCIENCE, 14(9), 20220914
    Link to Paper Search Results by DOI
  27. Impact of COVID-19 pandemic on epilepsy care in Japan: A national-level multicenter retrospective cohort study, EPILEPSIA OPEN, 7(3), 431-441, 202209
    Link to Paper Search Results by DOI
  28. Seizure Deterioration with Increased Levetiracetam Blood Concentration during the Postpartum Period in Refractory Temporal Lobe Epilepsy, INTERNAL MEDICINE, 61(8), 1237-1240, 2022
    Link to Paper Search Results by DOI
  29. A longitudinal seizure outcome following the COVID-19 pandemic in 2020 and 2021: Transient exacerbation or sustainable mitigation, JOURNAL OF THE NEUROLOGICAL SCIENCES, 434, 20220315
    Link to Paper Search Results by DOI
  30. Absence of an Autonomic Sign Assists in the Diagnosis of Extratemporal Lobe Epilepsy Manifesting Generalized Convulsion with Retained Awareness, Internal Medicine, 58(8), 1151-1155, 2019
  31. Low-dose perampanel improves refractory cortical myoclonus by the dispersed and suppressed paroxysmal depolarization shifts in the sensorimotor cortex, CLINICAL NEUROPHYSIOLOGY, 130(10), 1804-1812, 201910
    Link to Paper Search Results by DOI
  32. ★, A score to map the lateral nonprimary motor area: Multispectrum intrinsic brain activity versus cortical stimulation, EPILEPSIA, 60(11), 2294-2305, 201911
    Link to Paper Search Results by DOI
  33. Efficacy of wide-band electrocorticography on mapping of the primary seonsory-motor area compared with electrical cortical stimulation, Journal of the Neurological Sciences, 381, 86
  34. ★, A rational, multispectral mapping algorithm for primary motor cortex: A primary step before cortical stimulation, EPILEPSIA, 60, 547-559, 201903
    Link to Paper Search Results by DOI
  35. ★, Multi-component intrinsic brain activities as a safe, alternative to cortical stimulation for sensori-motor mapping in neurosurgery, Clinical Neurophysiology, 129(9), 2038-2048, 201809
    Link to Paper Search Results by DOI
  36. Shifting laxative dosing schedule to an earlier time improves refractory constipation in Parkinson's disease: a case series, Neurology and Clinical Neuroscience, 6(6), 182-184, 2018
  37. Elderly woman with exaggerated startle reflex and unconscious drop attack, Neurology and Clinical Neuroscience, 4(4), 156-158, 2016
  38. Seizures after intracerebral hemorrhage; risk factor, recurrence, efficacy of antiepileptic drug, Journal of the neurological sciences, 359(1-2), 318-322, 2015
  39. Ischemic stroke mortality is more strongly associated with anemia on admission than with underweight status, Journal of Stroke and Cerebrovascular Diseases, 26(6), 1369-1347
  40. Ability of the ankle brachial index and brachial-ankle pulse wave velocity to predict the 3-month outcome in patients with non-cardioembolic stroke, Japan Atherosclerosis Society, 38901
  41. Brain natriuretic peptide and particular left ventricle segment asynergy associated with cardioembolic stroke from old myocardial infarction, Journal of Stroke and Cerebrovascular Diseases, 25(5), 1165-1171
  42. ABI and baPWV Are Independent Predictive Factors for a Clinical Outcome in Acute Non-Cardioembolic Stroke: P061, Cerebrovascular Diseases, 40
  43. Acute ischemic stroke associated with nephrotic syndrome: Incidence and significance—Retrospective cohort study, eNeurologicalSci, 1(3-4), 47-50
  44. Risk Factors for Stroke/Prognosis Acute ischemic stroke associated with nephrotic syndrome: Prevalence and significance, International Journal of Stroke, 10
  45. Cerebrovascular Occlusive Disease Progression of responsible intracranial artery stenosis prior to ischemic stroke onset–Fukuyama Intracranial Artery Stenosis (FICAS) Study–, International Journal of Stroke, 9
  46. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area, EPILEPSY & BEHAVIOR, 117, 202104
    Link to Paper Search Results by DOI
  47. Rapid ping-pong eye deviation following a recovery from carbon dioxide narcosis, BMJ CASE REPORTS, 14(3), 202103
    Link to Paper Search Results by DOI
  48. Influence of current and previous smoking on current phenotype in Parkinson's disease, JOURNAL OF THE NEUROLOGICAL SCIENCES, 427, 20210815
    Link to Paper Search Results by DOI
  49. Psychiatric non-epileptic seizure: diagnostic utility of density spectral array, BMJ case reports, 14, e241015, 2021
  50. A Biomarker for Benign Adult Familial Myoclonus Epilepsy: High-Frequency Activities in Giant Somatosensory Evoked Potentials, Movement Disorders, 2021
  51. Emotional Facial Paresis in Temporal Lobe Epilepsy, Internal Medicine, 60(16), 2021
  52. Extreme delta brush in anti- NMDAR encephalitis: Mimics and chameleons, Epilepsia Open, 6, 443-446, 2021
  53. Efficacy of Lacosamide in a Patient with Refractory Generalized Epilepsy Based on Video Electroencephalography, Internal Medicine, 2021
  54. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study, Anaesthesia, 76(6), 748-758, 2021
  55. Marked response to perampanel: A decade-long course of giant somatosensory evokedpotentials in Unverricht-Lundborg disease, Clinical Neurophysiology, 132, 2329-2331, 2021
  56. ★, A Role of Aging in the Progression of Cortical Excitability in Benign Adult Familial Myoclonus Epilepsy type 1 Patients, Movement Disorders, 2021
  57. Nationwide online EEG education during coronavirus disease 2019 pandemic, Clinical Neurophysiology, 2021
  58. A case of repetitive seizures following immune checkpoint inhibitor therapy as a feature of autoimmune encephalitis, Epileptic Disorders, 2021
  59. Needs of Epilepsy Care from Inter-hospital Network System of Epilepsy: Sample Survey of the Epilepsy Clinic in Kyoto University Hospital, Journal of the Japan Epilepsy Society, 35(3), 2018
  60. A Biomarker for Benign Adult Familial Myoclonus Epilepsy: High-Frequency Activities in Giant Somatosensory Evoked Potentials, MOVEMENT DISORDERS, 36(10), 2335-2345, 202110
    Link to Paper Search Results by DOI
  61. Risk factors for psychological distress in electroencephalography technicians during the COVID-19 pandemic: A national-level cross-sectional survey in Japan, EPILEPSY & BEHAVIOR, 125, 202112
    Link to Paper Search Results by DOI
  62. Efficacy of Lacosamide in a Patient with Refractory Generalized Epilepsy Based on Video Electroencephalography, INTERNAL MEDICINE, 60(22), 3621-3624, 2021
    Link to Paper Search Results by DOI
  63. Barriers to telemedicine among physicians in epilepsy care during the COVID-19 pandemic: A national-level cross-sectional survey in Japan, EPILEPSY & BEHAVIOR, 126, 202201
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Treatment of functional neurological disorder: notification and afterwards, Shuichiro Neshige, The 121st Annual Meeting of the Japanese Neuropsychiatric Society, 2025, Without Invitation, Japanese
  2. Critical Care EEG: A Brain-Specific Vital Sign for ICU Physicians to Prevent Secondary Brain Injury, Shuichiro Neshige, The 52nd Annual Meeting of the Japanese Society of Intensive Care Medicine, 2025, Without Invitation, Japanese
  3. EEG reading should initially be performed without clinical information, Shuichiro Neshige, Japanese Epilepsy Society, 2022, With Invitation, Japanese
  4. Ictal-interictal continuum should be treated aggressively, Shuichiro Neshige, Japanese Epilepsy Society, 2022, With Invitation, Japanese
  5. Basics of Digital EEG Recording and First EEG Decoding, Shuichiro Neshige, Japanese Society of Clinical Neurophysiology, 2023, With Invitation, Japanese
  6. On Transient Epileptic Amnesia (TEA): Diagnosis and Treatment of TEA, Shuichiro Neshige, Japanese Epilepsy Society, 2024, With Invitation, Japanese
  7. Critical Care EEG in Practice; Diverse Perspectives, Shuichiro Neshige, Japanese Epilepsy Society, 2024, With Invitation, Japanese
  8. A rational, multi-spectrum mapping algorithm for primary motor cortex: a primary step before cortical stimulation, Shuichiro Neshige, Japanese Neurology Society Conference 2019, Without Invitation, Japanese, published
  9. Medical education during the COVID-19 pandemic in Japan: EEG-Webinar using an online application, Shuichiro Neshige, Without Invitation, English, published
  10. Socio-economic and psychological impact on epilepsy outside of the nation-wide COVID-19 pandemic area in Japan, Shuichiro Neshige, Japan Epilepsy Society Conference 2021, Without Invitation, English, published
  11. Socio-economic impact on epilepsy outside of the nation-wide COVID-19 pandemic area in Japan, Shuichiro Neshige, 13th Asian & Oceanian Epilepsy Congress, Without Invitation, English, published

Awards

  1. 44th JUHN AND MARY WADA awrd, Japanese Epilepsy Society
  2. 2018, Japanese Epilepsy Society Sponsored Award, Japanese Epilepsy Society
  3. 2018, Japanese Epilepsy Society,Hans Berger Award, Japanese Epilepsy Society

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Early-Career Scientists), 2020, 2022

Social Activities

History as Committee Members

  1. YES-JAPAN, 2020, 2022, Japanese Epilepsy Society
  2. English Journal Committee, Japanese Epilepsy Society
  3. Classification and Terminology Committee, Japanese Epilepsy Society
  4. Social Issues Review Committee, Japanese Epilepsy Society
  5. Systematic review, Japanese Society of Neurology
  6. Epilepsy Section, 2023, 2025, Japanese Society of Neurology