MASAHIRO OOHIRA

Last Updated :2024/05/07

Affiliations, Positions
Hiroshima University Hospital, Assistant Professor
E-mail
mohirahiroshima-u.ac.jp
Self-introduction
I am researching cancer immunity and transplantation immunity in hepatobiliary, pancreatic and transplantation fields. Specifically, I am investigating the mechanism of hepatocellular carcinoma recurrence and the development of therapeutic strategies. I am also engaged in research on regenerative medicine, which is cell therapy after liver surgery and liver transplantation.

Basic Information

Major Professional Backgrounds

  • 2009/04/01, 2009/08/31, Hiroshima University Hospital, Clinical Fellow
  • 2012/10/01, 2013/03/31, Hiroshima University Hospital, Clinical Fellow
  • 2013/04/01, 2014/03/31, Hiroshima University, Institute of Biomedical & Health Sciences, Assistant Professor (Special Appointment)
  • 2014/04/01, Hiroshima University Hospital, Assistant Professor
  • 2009/09/01, University of Miami, Department of Surgery, Research Associate III
  • 2011/06/01, University of Miami, Department of Surgery, Research Assistant Professor

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Digestive surgery

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, Intensive, Practice of Medicine I
  2. 2024, Undergraduate Education, Intensive, Practice of Medicine II
  3. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Gastroenterological and Transplant Surgery
  4. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Gastroenterological and Transplant Surgery
  5. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Gastroenterological and Transplant Surgery
  6. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Gastroenterological and Transplant Surgery

Research Activities

Academic Papers

  1. A phase I/II study of adoptive immunotherapy using donor liver graft-derived natural killer cells to prevent bloodstream infection after liver transplantation: a study protocol, Transl Med Commun, 7(1), 19, 20220803
  2. Surgery-related disseminated intravascular coagulation predicts postoperative complications, BMC SURGERY, 23(1), 20230411
    Link to Paper Search Results by DOI
  3. Effect of abdominal aortic calcification on the prognosis and recurrence of colorectal cancer stages II-III: A retrospective cohort study, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 38(1), 20230121
    Link to Paper Search Results by DOI
  4. Protection From Second Warm Ischemic Injury Using a Thermal Barrier Bag in Kidney Transplantation, TRANSPLANTATION DIRECT, 9(3), 202303
    Link to Paper Search Results by DOI
  5. Impact of Abdominal Aortic Calcification After Major Hepatobiliary Pancreatic Surgery: A Retrospective Cohort Study, ANTICANCER RESEARCH, 42(12), 5983-5989, 202212
    Link to Paper Search Results by DOI
  6. Adoptive immunotherapy with natural killer cells from peripheral blood CD34(+) stem cells to prevent hepatocellular carcinoma recurrence after curative hepatectomy: a study protocol for an open-label, single-arm phase I study, BMJ OPEN, 12(11), 202211
    Link to Paper Search Results by DOI
  7. Adoptive immunotherapy overcomes genetic susceptibility to bloodstream infections due to fc-gamma receptor polymorphisms after liver transplantation, AMERICAN JOURNAL OF TRANSPLANTATION, 22(10), 2392-2400, 202210
    Link to Paper Search Results by DOI
  8. Acute portal hypertension using portal vein ligation abrogates TRAIL expression of liver-resident NK cells, HEPATOLOGY COMMUNICATIONS, 6(9), 2551-2564, 202209
    Link to Paper Search Results by DOI
  9. Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation, HUMAN IMMUNOLOGY, 83(6), 494-498, 202206
    Link to Paper Search Results by DOI
  10. Adoptive transfer of TRAIL-expressing natural killer cells prevents recurrence of hepatocellular carcinoma after partial hepatectomy, TRANSPLANTATION, 82(12), 1712-1719, 20061227
    Link to Paper Search Results by DOI
  11. Significant Correlation Between Spleen Volume and Thrombocytopenia in Liver Transplant Patients: A Concept for Predicting Persistent Thrombocytopenia, LIVER TRANSPLANTATION, 15(2), 208-215, 200902
    Link to Paper Search Results by DOI
  12. Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice, JOURNAL OF CLINICAL INVESTIGATION, 119(11), 3226-3235, 200911
    Link to Paper Search Results by DOI
  13. Clinical-Scale Isolation of Interleukin-2-Stimulated Liver Natural Killer Cells for Treatment of Liver Transplantation With Hepatocellular Carcinoma, CELL TRANSPLANTATION, 21(7), 1397-1406, 2012
    Link to Paper Search Results by DOI
  14. Comparative Analysis of T-Cell Depletion Method for Clinical Immunotherapy-Anti-Hepatitis C Effects of Natural Killer Cells Via Interferon-gamma Production, TRANSPLANTATION PROCEEDINGS, 45(5), 2045-2050, 201306
    Link to Paper Search Results by DOI
  15. Possibility of Adoptive Immunotherapy With Peripheral Blood-derived CD3(-)CD56(+) and CD3(+)CD56(+) Cells for Inducing Antihepatocellular Carcinoma and Antihepatitis C Virus Activity, JOURNAL OF IMMUNOTHERAPY, 34(2), 137-146, 201103
    Link to Paper Search Results by DOI
  16. Impact of Adjuvant Immunotherapy Using Liver Allograft-Derived Lymphocytes on Bacteremia in Living-Donor Liver Transplantation, TRANSPLANTATION, 92(5), 575-580, 201109
    Link to Paper Search Results by DOI
  17. Potential Benefit of Mixed Lymphocyte Reaction Assay-based Immune Monitoring After Living Donor Liver Transplantation for Recipients With Autoimmune Hepatitis, TRANSPLANTATION PROCEEDINGS, 46(3), 785-789, 201404
    Link to Paper Search Results by DOI
  18. Clinical Efficacy of Simultaneous Splenectomy in Liver Transplant Recipients With Hepatitis C Virus, TRANSPLANTATION PROCEEDINGS, 46(3), 770-773, 201404
    Link to Paper Search Results by DOI
  19. Bile CXC Motif Chemokine 10 Levels Correlate With Anti-donor Cytotoxic T Cell Responses After Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 46(3), 790-793, 201404
    Link to Paper Search Results by DOI
  20. Risk Factors for Development of New-Onset Diabetes Mellitus and Progressive Impairment of Glucose Metabolism After Living-Donor Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 46(3), 865-869, 201404
    Link to Paper Search Results by DOI
  21. Multiple Hepatic Vein Reconstruction Using an All-in-one Sleeve Patch Graft Technique in Living Donor Liver Transplantation: A Case Report, TRANSPLANTATION PROCEEDINGS, 46(3), 982-985, 201404
    Link to Paper Search Results by DOI
  22. Impact of alloimmune T cell responses on hepatitis C virus replication in liver transplant recipients, HUMAN IMMUNOLOGY, 75(12), 1259-1267, 201412
    Link to Paper Search Results by DOI
  23. Prevention of infection after liver transplantation, 11(1), 61-67, 201402
  24. Treatment of hepatic amyloid light-chain amyloidosis with bortezomib and dexamethasone in a liver transplant patient., Hepatology Research, 45(10), E150-E155, 20150122
  25. Pancreaticoduodenectomy with preservation of gastric tube blood flow after esophagectomy: Report of a case., Int J Surg Case Rep., 201408
  26. Difference in cytotoxicity against hepatocellular carcinoma between liver and periphery natural killer cells in humans., Hepatology, 43(2), 362-372, 20060128
  27. Possible therapeutic effect of lipid supplementation on neurological complications in liver transplant recipients, Transpl Int, 20(7), 632-635, 20070420
  28. Microsurgical hepatic artery reconstruction during living-donor liver transplantation by using head-mounted surgical binocular system, Transpl Int, 20(11), 970-973, 20070720
  29. Prophylaxis against recurrence of HBV hepatitis after living-donor liver transplantation, Hepatogastroenterology, 55(86-87), 1746-1749, 20081224
  30. Using recipient's middle hepatic vein for drainage of the right paramedian sector in right liver graft, Transplantation, 86(11), 1565-1571, 20081217
  31. Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness, Transpl Int, 22(8), 805-813, 20090606
  32. Efficacy and Feasibility of Salvage Living Donor Liver Transplantation after Initial Liver Resection in Patients with Hepatocellular Carcinoma, Dig Surg, 33(1), 8-14, 2015
  33. An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma, Dig Surg, 33(1), 43-50, 2015
  34. Treatment of hepatic amyloid light-chain amyloidosis with bortezomib and dexamethasone in a liver transplant patient, HEPATOLOGY RESEARCH, 45(10), E150-E155, 201510
    Link to Paper Search Results by DOI
  35. Efficacy and Feasibility of Salvage Living Donor Liver Transplantation after Initial Liver Resection in Patients with Hepatocellular Carcinoma, DIGESTIVE SURGERY, 33(1), 8-14, 2016
    Link to Paper Search Results by DOI
  36. An Analysis of Surgical Treatment for the Spontaneous Rupture of Hepatocellular Carcinoma, DIGESTIVE SURGERY, 33(1), 43-50, 2016
    Link to Paper Search Results by DOI
  37. Fc-Gamma Receptor Polymorphisms Predispose Patients to Infectious Complications After Liver Transplantation, AMERICAN JOURNAL OF TRANSPLANTATION, 16(2), 625-633, 201602
    Link to Paper Search Results by DOI
  38. Intraoperative assessment of tissue oxygen saturation of the remnant stomach by near-infrared spectroscopy in two cases of pancreatectomy following gastrectomy, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 22, 75-78, 2016
    Link to Paper Search Results by DOI
  39. Inflammatory pseudotumor of the liver occurring during the course of hepatitis C virus-related hepatocellular carcinoma treatment: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 20, 96-100, 2016
    Link to Paper Search Results by DOI
  40. Different sensitivity of rituximab-treatment to B-cells between ABO-incompatible kidney and liver transplantation, HUMAN IMMUNOLOGY, 77(6), 456-463, 201606
    Link to Paper Search Results by DOI
  41. Stepwise approach to curative surgery using percutaneous transhepatic cholangiodrainage and portal vein embolization for severe bile duct injury during laparoscopic cholecystectomy: a case report, SURGICAL CASE REPORTS, 2, 20160517
    Link to Paper Search Results by DOI
  42. Prediction of long-term survival by using the Glasgow Prognostic Score in patients with hepatocellular carcinoma after liver transplantation, HEPATOLOGY RESEARCH, 46(7), 622-633, 201606
    Link to Paper Search Results by DOI
  43. CD52-Negative NK Cells Are Abundant in the Liver and Less Susceptible to Alemtuzumab Treatment, PLoS One, 11(8), e0161618, 2016
  44. Intrahepatic cholangiocarcinoma coinciding with a liver metastasis from a rectal carcinoma: a case report, Surg Case Rep, 2(1), 94, 20160909
  45. Pseudolymphoma of the liver: a case report and literature review., Surg Case Rep, 1(1), 107, 2015
  46. A case of biliary cystic tumor with repeated hemobilia., Surg Case Rep, 1(1), 34, 2015
  47. CD52-Negative NK Cells Are Abundant in the Liver and Less Susceptible to Alemtuzumab Treatment, PLOS ONE, 11(8), 20160825
    Link to Paper Search Results by DOI
  48. MELD and Child-Pugh Scores Are Related to Immune Status of Intrahepatic Natural Killer Cells in Liver Transplant Candidates, TRANSPLANTATION PROCEEDINGS, 49(1), 98-101, 2017
    Link to Paper Search Results by DOI
  49. Evaluation of the risk factors and prognostic factors of hepatectomy for hepatocellular carcinoma in patients aged 80 years or more, JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 24(1), 58-64, 201701
    Link to Paper Search Results by DOI
  50. Efficacy of repeat hepatectomy for recurrence following curative hepatectomy for colorectal liver metastases: A Retrospective Cohort Study of 128 patients, INTERNATIONAL JOURNAL OF SURGERY, 36, 96-103, 201612
    Link to Paper Search Results by DOI
  51. Elective laparoscopic deroofing to treat the spontaneous rupture of a large simple liver cyst: a case report, SURGICAL CASE REPORTS, 2, 20161207
    Link to Paper Search Results by DOI
  52. Predictive Independent Factors for Extrahepatic Metastasis of Hepatocellular Carcinoma Following Curative Hepatectomy, ANTICANCER RESEARCH, 37(5), 2625-2631, 201705
    Link to Paper Search Results by DOI
  53. Biliary-duodenal anastomosis using magnetic compression following massive resection of small intestine due to strangulated ileus after living donor liver transplantation: a case report, SURGICAL CASE REPORTS, 3, 20170525
    Link to Paper Search Results by DOI
  54. Impact of Steroids on Natural Killer Cells Against Cytotoxicity and Hepatitis C Virus Replication, TRANSPLANTATION PROCEEDINGS, 49(5), 1160-1164, 201706
    Link to Paper Search Results by DOI
  55. Prediction of recurrence following hepatectomy in patients with hepatitis C virus infection-related hepatocellular carcinoma who achieved a sustained virological response., Hepatol Res, 20170323
  56. Perforation of the gallbladder in a patient with acute cytomegalovirus cholecystitis shortly following renal transplantation., Transpl Infect Dis., 20170613
  57. Effect of Fc-g Receptor Polymorphism on Rituximab-Mediated B Cell Depletion in ABO-Incompatible Adult Living Donor Liver Transplantation., Transplant Direct, 3(6), e164, 20170618
  58. Aggressive angiomyxoma of the liver: a case report and literature review, Surg Case Rep, 3(1), 92, 20170824
  59. Acute Graft Rejection and Formation of De Novo Donor-Specific Antibodies Triggered by Low Cyclosporine Levels and Interferon Therapy for Recurrent Hepatitis C Infection After Liver Transplantation: A Case Report, Transplant Proc, 49(7), 1634-1638, 20170825
  60. Aggressive angiomyxoma of the liver: a case report and literature review, SURGICAL CASE REPORTS, 3, 20170823
    Link to Paper Search Results by DOI
  61. Acute Graft Rejection and Formation of De Novo Donor-Specific Antibodies Triggered by Low Cyclosporine Levels and Interferon Therapy for Recurrent Hepatitis C Infection After Liver Transplantation: A Case Report, TRANSPLANTATION PROCEEDINGS, 49(7), 1634-1638, 201709
    Link to Paper Search Results by DOI
  62. Prediction of recurrence following hepatectomy in patients with hepatitis C virus infection-related hepatocellular carcinoma who achieved a sustained virological response, HEPATOLOGY RESEARCH, 47(11), 1186-1195, 201710
    Link to Paper Search Results by DOI
  63. Perforation of the gallbladder in a patient with acute cytomegalovirus cholecystitis shortly following renal transplantation, TRANSPLANT INFECTIOUS DISEASE, 19(5), 201710
    Link to Paper Search Results by DOI
  64. Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice, PLOS ONE, 12(10), 20171031
    Link to Paper Search Results by DOI
  65. Utility of hepatobiliary scintigraphy for recurrent reflux cholangitis following choledochojejunostomy: A case report, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 42, 104-108, 2018
    Link to Paper Search Results by DOI
  66. A case report on the successful perioperative management of hepatectomy for hepatocellular carcinoma in a patient with von Willebrand disease, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 44, 131-134, 2018
    Link to Paper Search Results by DOI
  67. A Phased Desensitization Protocol With Rituximab and Bortezomib for Highly Sensitized Kidney Transplant Candidates, TRANSPLANTATION DIRECT, 1(5), 201506
    Link to Paper Search Results by DOI
  68. A case of biliary cystic tumor with repeated hemobilia, SURGICAL CASE REPORTS, 1, 2015
    Link to Paper Search Results by DOI
  69. Pseudolymphoma of the liver: a case report and literature review, SURGICAL CASE REPORTS, 1, 2015
    Link to Paper Search Results by DOI
  70. Hepatic irradiation persistently eliminates liver resident NK cells, PLOS ONE, 13(6), e0198904, 20180613
    Link to Paper Search Results by DOI
  71. Prognostic factors in patients with recurrent intrahepatic cholangiocarcinoma after curative resection: A retrospective cohort study, INTERNATIONAL JOURNAL OF SURGERY, 54, 156-162, 201806
    Link to Paper Search Results by DOI
  72. Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution, SURGERY, 164(2), 219-226, 201808
    Link to Paper Search Results by DOI
  73. Polymorphisms in TRAIL predict long-term survival and extrahepatic recurrence following initial hepatectomy for hepatocellular carcinoma, J Hepatobiliary Pancreat Sci, 25(8), 370-376, 20180728
  74. Independent risk factors that predict bile leakage after hepatectomy for hepatocellular carcinoma: Cohort study, Int J Surg, 57, 1-7, 20180724
  75. Hybrid Surgery for Portosystemic Encephalopathy in a Patient with Liver Cirrhosis: a case report, Hiroshima Journal of Medical Sciences, 66(1), 11-15, 201703
  76. Independent risk factors that predict bile leakage after hepatectomy for hepatocellular carcinoma: Cohort study, INTERNATIONAL JOURNAL OF SURGERY, 57, 1-7, 201809
    Link to Paper Search Results by DOI
  77. Impact of Abdominal Aortic Calcification Among Liver Transplantation Recipients, LIVER TRANSPLANTATION, 25(1), 79-87, 201901
    Link to Paper Search Results by DOI
  78. Risk Factors for Refractory Ascites After Living Donor Liver Transplant, TRANSPLANTATION PROCEEDINGS, 51(5), 1516-1519, 201906
    Link to Paper Search Results by DOI
  79. Simultaneous Liver-Kidney Transplantation in Patient with a History of Heparin-Induced Thrombocytopenia: A Case Report and Literature Review, AMERICAN JOURNAL OF CASE REPORTS, 20, 980-987, 20190709
    Link to Paper Search Results by DOI
  80. Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation, TRANSPLANTATION PROCEEDINGS, 51(6), 1934-1938, 2019
    Link to Paper Search Results by DOI
  81. Management of Refractory Ascites for Liver Transplant Candidates: A Novel Cell-free and Concentrated Ascites Reinfusion Therapy, TRANSPLANTATION PROCEEDINGS, 51(8), 2740-2744, 201910
    Link to Paper Search Results by DOI
  82. Utility of Doppler Ultrasonography in Liver Transplantation With Celiac Axis Compression Syndrome: A Case Report, TRANSPLANTATION PROCEEDINGS, 51(9), 3103-3106, 201911
    Link to Paper Search Results by DOI
  83. Hepatic epithelioid hemangioendothelioma successfully treated with living donor liver transplantation: A case report and literature review, CLINICAL CASE REPORTS, 8(1), 108-115, 20200101
    Link to Paper Search Results by DOI
  84. Everolimus enhances TRAIL-mediated anti-tumor activity of liver resident natural killer cells in mice, TRANSPLANT INTERNATIONAL, 33(2), 229-243, 20200201
    Link to Paper Search Results by DOI
  85. Successful Treatment of Chronic Myeloid Leukemia With Dasatinib After Kidney Transplantation: A Case Report, TRANSPLANTATION PROCEEDINGS, 52(2), 600-603, 20200301
    Link to Paper Search Results by DOI
  86. Essential updates 2018/2019: Liver transplantation, ANNALS OF GASTROENTEROLOGICAL SURGERY, 4(3), 195-207, 20200501
    Link to Paper Search Results by DOI
  87. Posttransplant Management of Recipients Undergoing Liver Transplantation for Hepatocellular Carcinoma. Working Group Report From the ILTS Transplant Oncology Consensus Conference, TRANSPLANTATION, 104(6), 1143-1149, 20200601
    Link to Paper Search Results by DOI
  88. Treatment outcomes after splenectomy with gastric devascularization or balloon-occluded retrograde transvenous obliteration for gastric varices: a propensity score-weighted analysis from a single institution, JOURNAL OF GASTROENTEROLOGY, 55(9), 877-887, 20200901
    Link to Paper Search Results by DOI
  89. Strategies for Deliberate Induction of Immune Tolerance in Liver Transplantation: From Preclinical Models to Clinical Application, FRONTIERS IN IMMUNOLOGY, 11, 20200731
    Link to Paper Search Results by DOI
  90. Impact on biliary complications of donor abdominal aortic calcification among living donor liver transplantation: a retrospective study, TRANSPLANT INTERNATIONAL, 33(12), 1745-1753, 20201201
    Link to Paper Search Results by DOI
  91. Rapidly Progressive Invasive Urothelial Carcinoma With Flat and Infiltrative Growth Pattern in the Graft Kidney After Living-Related Kidney Transplantation: A Case Report, TRANSPLANTATION PROCEEDINGS, 52(9), 2726-2730, 20201101
    Link to Paper Search Results by DOI
  92. Obliteration of a Portosystemic Shunt by Hybrid Interventional Radiology Using a Transmesenteric Approach Under Minilaparotomy After Liver Transplantation: A Case Report, TRANSPLANTATION PROCEEDINGS, 52(9), 2762-2766, 20201101
    Link to Paper Search Results by DOI
  93. Analysis of Risk Factors Affecting Incidence of Osteoporosis and Fragility Fractures in Liver Transplant Recipients, ANNALS OF TRANSPLANTATION, 26, 20210205
    Link to Paper Search Results by DOI
  94. Loss of antibodies to hepatitis E virus in organ transplant patients with hepatitis E, HEPATOLOGY RESEARCH, 51(5), 538-547, 20210501
    Link to Paper Search Results by DOI
  95. Pilot study to determine the safety and feasibility of deceased donor liver natural killer cell infusion to liver transplant recipients with hepatocellular carcinoma, Cancer Immunol Immunother, 20210721
  96. Risk Factors for Hepatocellular Carcinoma After Splenectomy in Liver Cirrhotic Patients, Am Surg, 20210831
  97. Molecular mismatch predicts T cell mediated rejection and de novo donor specific antibody formation after living-donor liver transplantation, Liver Transpl, 20210727
  98. B cell depletion with anti-CD20 mAb exacerbates anti-donor CD4(+) T cell responses in highly sensitized transplant recipients, SCIENTIFIC REPORTS, 11(1), 20210913
    Link to Paper Search Results by DOI
  99. Molecular Mismatch Predicts T Cell-Mediated Rejection and De Novo Donor-Specific Antibody Formation After Living Donor Liver Transplantation, LIVER TRANSPLANTATION, 27(11), 1592-1602, 202111
    Link to Paper Search Results by DOI
  100. Treatment of multiple huge liver cysts in a hybrid operating room: a case report, SURGICAL CASE REPORTS, 7(1), 20211029
    Link to Paper Search Results by DOI
  101. Impact of abdominal aortic calcification on clinical outcomes following initial hepatectomy for hepatocellular carcinoma: A retrospective cohort study, ANNALS OF GASTROENTEROLOGICAL SURGERY, 6(1), 149-158, 202201
    Link to Paper Search Results by DOI
  102. Pilot study to determine the safety and feasibility of deceased donor liver natural killer cell infusion to liver transplant recipients with hepatocellular carcinoma, CANCER IMMUNOLOGY IMMUNOTHERAPY, 71(3), 589-599, 202203
    Link to Paper Search Results by DOI

Publications such as books

  1. 2015/10/27, Gene Therapy and Cell Therapy Through the Liver, Novel immunotherapy using liver-derived natural killer cells for preventing hepatocellular carcinoma recurrence in liver transplantation, Springer, 2015, 10, Scholarly Book, Joint work, Ohira M, Nishida S, Tzakis A, Ohdan H, ISBN-10: 4431556656, 185, 35-45
    Amazon URL

Invited Lecture, Oral Presentation, Poster Presentation

  1. Phase I study of adjuvant immunotherapy using donor liver derived NK cells for preventing HCC recurrence after liver transplantation, Masahiro Ohira, Yuki Imaoka, Koki Sato, Koki Imaoka, Naoki Tanimine, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Andreas G Tzakis, Seigo Nishida, Hideki Ohdan, ILTS 2022, 2022/05/04, Without Invitation, English
  2. Clinical efficacy of adjuvant immunotherapy for liver transplant recipients with exceeding Japan criteria of hepatocellular carcinoma using donor liver derived natural killer cells, Masahiro Ohira, Yuki Imaoka, Koki Sato, Koki Imaoka, Naoki Tanimine, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Andreas G Tzakis, Seigo Nishida, Hideki Ohdan, American Transplant Congress 2022, 2022/06/04, Without Invitation, English
  3. International Liver Transplantation Society (ILTS) Congress, Naofumi Tsukiyama, Yuka Tanaka, Akhmet Seidakhmetov, Yuki Imaoka, Ryosuke Nakano, Naoki Tanimine, Doskali Marlen, Masahiro Ohira, Hiroyuki Tahara, Kentaro Ide, Hideki Ohdan, American Transplant Congress 2022, 2022/06/04, Without Invitation, English
  4. Analysis of intracellular signaling mediated by the aryl hydrocarbon receptor (AhR) in liver-resident NK cells, Koki Sato, Koki Sato,Masahiro Ohira, Yuki Imaoka, Koki Imaoka, Ryosuke Nakano, Naoki Tanimine, Shintaro Kuroda, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan, International Liver Transplantation Society (ILTS) Congress, 2022/05/04, Without Invitation, English
  5. Polymorphisms in CTLA-4 predict de novo donor specific antibody formation after kidney transplantation, Kosuke Ono, Kosuke Ono, Kentaro Ide, Hiroaki Yamane, Shuji Akimoto, Naoki Tanimine, Hiroyuki Tahara, Masahiro Ohira, Yuka Tanaka, Hideki Ohdan, American Transplant Congress 2022, 2022/06/04, Without Invitation, English
  6. Safety and efficacy of novel cell-free and concentrated ascites reinfusion therapy (KM-CART) for refractory ascites in liver transplant candidates, Sato K, Ohira M,Imaoka Y,Hashimoto S,Tahara H,Ide K,Kobayashi T,Tanaka Y,Ohdan H, 19th Congress of the Euuropean Society for Organ Transplantation, 2019/09/15, Without Invitation, English
  7. Class II HLA Eplet mismatch is a risk factor for de novo Donor-Specific antibody development in kidney transplantation recipient., Yamane H, Tanaka Y,Ono K,Ohira M,Tahara H,Ide K,Ohdan H, 19th Congress of the Euuropean Society for Organ Transplantation, 2019/09/15, Without Invitation, English
  8. INVESTIGATION OF FACTORS AFFECTING PERIOPERATIVE NUTRITIONAL STATUS IN KIDNEY TRANSPLANTATION, Akimoto S, Tahara H, Akhmet Seidakhmetov,Yamane H,Sato K,Imaoka Y,Honmyo N,Nakashima I,Taguchi K,Tanaka A,Jamilya Saparbay,Doskali Marlen, Hashimoto S,Ohira M,Ide K,Tanaka Y,Ohdan H, 19th Congress of the Euuropean Society for Organ Transplantation, 2019/09/15, Without Invitation, English
  9. Surgery-related DIC Predicts the Severity of Complication after Major Hepatobiliary Pancreatic Surgery, Seidakhmetov Akhmet, Imaoka Y,Ohira M,Sato K,Uemura K,Kuroda S,Tahara H,Ide K, Kobayashi T,Ohdan H, A-PHPBA2019, 2019/09/04, Without Invitation, English
  10. Surgery-related DIC Predicts the Severity of Complication after Major Hepatobiliary Pancreatic Surgery, Seidakhmetov Akhmet, Imaoka Y,Ohira M,Sato K,Uemura K,Kuroda S,Tahara H,Ide K,Kobayashi T,Ohdan H, The Liver Week 2019, 2019/06/20, Without Invitation, English
  11. Impact of Donor Abdominal Aortic Calcification On Bile Duct Complication of Recipients After Livinf Donor Liver Transplantation: A Retrospective Study, imaoka Y, Ohira M,Sato K,Hashimoto S,Tahara H,Ide K,Kobayashi T,Tanaka Y,Ohdan H, 2019 American Transplant Congress, 2019/06/01, Without Invitation, English
  12. Novel cell-free and concentrated ascites reinfusion therapy (KM-CART) for management of refractory ascites in liver transplant candidates, Sato K, Ohira M,Imaoka Y,Hashimoto S,Tahara H,Ide K,Kobayashi T,Tanaka Y,Ohdan H, American Transplant Congress 2019, 2019/06/01, Without Invitation, English
  13. Adjuvant Immunotherapeutic Approach For Liver Transplant Recipients With Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells, Ohira M, Imaoka Y,Sato K,Tahara H,Ide K,Kobayashi T,Tanaka Y,Ohdan H, 2019 American Transplant Congress, 2019/06/01, Without Invitation, English
  14. B-cell depletion with rituximab exacerbates anti-donor CD4+ T-Cell responses in patients with donor-specific anti-human leukocyte antigen antibodies, Kentaro Ide, Yuka Tanaka, Hiroyuki Tahara, Masahiro Ohira, Seiichi Shimizu, Asuka Tanaka, Hideki Ohdan, 27th International Congress of the Transplantation Society, 2018/06/30, Without Invitation, English
  15. Predictive factors analysis of osteoporosis and fragility fractures after liver transplantation, Shuji Akimoto, Hiroyuki Tahara, Das Lalit Kumar, Yuki Imaoka, Naruhiko Honmyo, Ikki Nakashima, Kazuhiro Taguchi, Asuka Tanaka, Ryosuke Nakano, Jamilya Saparbay, Nobuki Ishida, Senichiro Yanagawa, Hiroshi Sakai, Seiichi Shimizu, Masahiro Ohira, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan, 27th International Congress of The Transplantation Society, 2018/06/30, Without Invitation, English
  16. Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; A retrospective study, Yuki　Imaoka, Masahiro Ohira, Takuya Yano, Ryosuke Nakano, Naoki Tanimine, Seiichi Shimizu, Shintaro Kuroda, Hiroyuki Tahara, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan, 2018 American Transplant Congress, 2018/06/02, Without Invitation, English
  17. B-cell depletion with rituximab exacerbates anti-donor CD4+ T-Cell responses in patients with donor-specific anti-human leukocyte antigen antibodies, Tanaka A, Kentaro Ide, Yuka Tanaka, Masahiro Ohira, Hiroyuki Tahara, Seiichi Shimizu, Hideki Ohdan., 2018 American Transplant Congress, 2018/06/02, Without Invitation, English
  18. Impact of Polymorphisms in TRAIL among hepatectomy for primary hepatocellular carcinoma, Yuki　Imaoka, Masahiro Ohira, Hideki Ohdan, The 17th meeting of the Society for Natural Immunity, 2018/05/28, Without Invitation, English
  19. Novel immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation, Masahiro Ohira, Ryosuke Nakano, Yuki Imaoka, Yuka Tanaka, Seiichi Shimizu, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Andreas G Tzakis, Seigo Nishida, Hideki Ohdan, The 17th meeting of the Society for Natural Immunity, 2018/05/28, Without Invitation, English
  20. Impact of multiplicity of functional KIR-HLA compound genotypes in liver transplantation, Yano T., Tanimine N, Kurita E, Nakano R, Shimizu S, Ohira M, Ishiyama K, Tanaka Y, Ohdan H, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  21. Prognosis after liver resection for intermediate stage hepatocellular carcinoma, Okimoto.S, Kobayashi T, Kudora S, Ishiyama K, Ide K, Ohira M, Tahara H, Shimizu S, Ohdan H, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  22. Anatomical hepatectomy with the midline incision for right-sided liver tumors, Kobayashi T, Sho Okimoto, Shintaro Kuroda,Michinori Hamaoka,Seiichi Shimizu,Hiroyuki Tahara,Masahiro Ohira,Kentaro Ide,Kohei Ishiyama,Hideki Ohdan, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  23. Fcg receptor polymorphism influences the effect of rituximab on B-cell depletion in ABO-incompatible adult living donor liver transplantation, Sakai H, Hiroshi Sakai, Yuka Tanaka, Seiichi Shimizu, Kentaro Ide, Kohei Ishiyama, Takashi Onoe, Masahiro Ohira, Hiroyuki Tahara, Tsuyoshi Kobayashi and Hideki Ohdan, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  24. Approaches to improve pancreas transplant outcome at Hiroshima University, Kohei Ishiyama, Hiroyuki Tahara, Masahiro Ohira, Kentaro Ide, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  25. The management for portal vein thrombosis / stenosis in liver transplantation, Seiichi Shimizu, Takashi Onoe, Hirotaka Tashiro, Kohei Ishiyama, Kentaro Ide, Masahiro Ohira, Hiroyuki Tahara, Tsuyoshi Kobayashi, Shintaro Kuroda, and Hideki Ohdan, 6th A-PHPBA/29th JSHBPS, 2017/06/07, Without Invitation, English
  26. Evaluation of Immunological States of Patients with Cytomegalovirus Infection After Kidney Transplantation, Tanaka A, Kentaro Ide, Yuka Tanaka, Kohei Ishiyama, Masahiro Ohira, Hiroyuki Tahara, Seiichi Shimizu, Das Lalit Kumar and Hideki Ohdan, American Transplant Congress 2017, 2017/04/29, Without Invitation, English
  27. Current status of desensitization protocol for highly HLA-sensitized kidney transplant candidates, 2017/02/15, Without Invitation, English
  28. Corticosteroids dampen Natural Killer cell function including cytotoxicity and anti-HCV effect, Masahiro Ohira, Ryuichi Hotta, Takuya Yano, Ryosuke Nakano, Andreas Tzakis, Seigo Nishida, Hideki Ohdan, Asian Transplantation Week 2016, 2016/10/29, Without Invitation, English
  29. Cotransplantation of preactivated mesenchymal stem cells inhibits liver natural killer cell–induced islet graft injury during instant blood-mediated inflammatory reaction after syngeneic intraportal islet transplantation, Ishida N Ohdan H, Ishiyama K, Saeki Y, Tanaka Y, Tahara H, Verma S, Saparbay D, Sasaki Y, Onoe T, Ohira M, Yano T, Yanagawa S, Taguchi K, Piao J, Tanaka A, Ide K, Shimizu S, Das L K, Nakano R., 26th International Congress of the Transplantation Society, 2016/08/18, Without Invitation, English
  30. Negative influence of liver irradiation on liver resident NK cells., Nakano R Ohira M, Yano T, Ohdan H., 26th International Congress of the Transplantation Society, 2016/08/18, Without Invitation, English
  31. Different sensitivity of rituximab-treatment to B-cells between ABO-incompatible kidney and liver transplantation., Tanaka A Morimoto H, IdeK, Tanaka Y, Ishiyama K, Ohira M, Tahara H, Shimizu S, Saeki Y, Sakai H, Tano T, Ishida N, Yanagawa S, Tagushi K, Nakano R, Ohdan H., 26th International Congress of the Transplantation Society, 2016/08/18, Without Invitation, English
  32. Reduction in CXCL9–CXCR3 signals diminishes TRAIL-expressing liver NK cells in partially hepatectomized mice under depressed immune status., Yano T Ohira M, Nakano R, Ohdan H., 26th International Congress of the Transplantation Society, 2016/08/18, Without Invitation, English
  33. Immunotherapy using donor liver NK cells for preventing severe infection after liver transplantation, 2016/07/13, Without Invitation, Japanese
  34. The Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) predicts the risk of excessive alcohol consumption in patients, Yano T. Ohira M, Sakamoto R, Narisada A, Tahara H, Ide K, Ishiyama K, Ohdan H., Transplantation Science Symposium Asian Regional Meetingb 2016, 2016/04/08, Without Invitation, Japanese
  35. A phased desensitization protocol with rituximab and bortezomib for highly HLA-sensitized kidney transplant candidates., Ide K Tanaka Y, Sasaki Y, Tahara H, Ohira M, Ishiyama K, Tashiro H, Ohdan H., CAST 2015, 2015/08/23, Without Invitation, English
  36. A case report of successful ABO incompatible renal transplantation from a well-treated HCV positive donor with SVR to HCV negative recipient without any viral transplantation., Verma S Ide K, Shimizu S, Ishiyama K, Ohira M, Tahara H, Tanaka Y, Das KL, Tashiro H, Ohdan H., CAST 2015, 2015/08/23, Without Invitation, English
  37. ERAS using early enteral nutrition prevents systemic inflammatory response syndrome and infection after living donor liver transplantation., Onoe T, Tanaka Y, Ishiyama K, Ide K, Ohira M, Tahara H, Kobayashi T, Kuroda S, Tashiro H, Ohdan H, A-PHPBA 2015, 2015/03/17, Without Invitation, English

Awards

  1. 2006, 2006 World Transplant Congress Young Investigator Award, World Transplant Congress
  2. 2009, 2009 American Transplant Congress Young Investigator Award, American Transplant Congress
  3. 2011, 2011 Annual Scientific Exchange Young Innovator Award, ASTS
  4. 2014, 2014 ILTS Young Investigator Award, ILTS, Novel adjuvant immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation.
  5. 2016/10/29, 2016 Asian Transplant Week, Best Abstract Award (Silver), Asian Transplant Society

Social Activities

History as Peer Reviews of Academic Papers

  1. 2021, Frontiers in Immunology, Others, 1
  2. 2021, Annals of Transplantation, Others, 1
  3. 2013, Hepatology Research, Others, Reviewer, 2
  4. 2013, Transplant International, Others, Reviewer, 1
  5. 2014, Transplant International, Others, Reviewer, 1
  6. 2014, Hepatology Research, Others, Reviewer, 1
  7. 2014, Surgery Today, Others, Reviewer, 1
  8. 2015, Hepatology Research, Others, Reviewer, 2
  9. 2015, Transplant International, Others, Reviewer, 1
  10. 2016, Hepatology Research, Others, Reviewer, 1
  11. 2016, Asia-Pacific Journal of Clinical Oncology, Others, Reviewer, 1
  12. 2016, World Journal of Gastroenterology, Others, Reviewer, 3
  13. 2016, Clinical Journal of Gastroenterology, Others, Reviewer, 1
  14. 2016, World Journal of Radiology, Others, Reviewer, 1
  15. 2017, World Journal of Gastroenterology, Others, Reviewer, 10
  16. 2017, Surgery Today, Others, Reviewer, 1
  17. 2017, World Journal of Hepatology, Others, Reviewer, 1
  18. 2017, Transplant International, Others, Reviewer, 1
  19. 2017, Clinical Transplantation, Others, Reviewer, 1