SIMENG MA

Last Updated :2026/06/02

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Assistant Professor
E-mail
masimenghiroshima-u.ac.jp
Other Contact Details
1-2-3 Kasumi Minami-ku, Hiroshima, Japan, Japan
TEL : (+81)82-257-5312 FAX : (+81)
Self-introduction
My current research focuses on elucidating the pathological mechanisms of chronic pain. In particular, I am working to clarify the functions of glial cells, such as microglia and astrocytes, in the brain, and based on this knowledge, am engaged in developing novel therapeutic strategies.

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical and Health Sciences, Division of Integrated Health Sciences(Doctoral Course)Program of Medicinal Sciences, Japan, 2022/10, 2025/09
  • Hiroshima University, Graduate School of Biomedical and Health Sciences, Division of Integrated Health Sciences(Master's Course)Program of Medicinal Sciences, Japan, 2020/10, 2022/09
  • Hiroshima University, Graduate School of Biomedical and Health Sciences, Research Student, Japan, 2019/10, 2020/09
  • South–Central Minzu University, School of Pharmaceutical Sciences, Pharmaceutical Analysis, China, 2015/09, 2019/06

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Research Activities

Academic Papers

  1. ★, Preventive effect of RAGE antagonists on distal infraorbital nerve injury-induced pain behaviors of male and female mice, Biochemical Pharmacology, 2025
    Link to Paper Search Results by DOI
  2. Intranasal treatment with cannabinoid 2 receptor agonist HU-308 ameliorates cold sensitivity in mice with traumatic trigeminal neuropathic pain, Cells, 2024
    Link to Paper Search Results by DOI
  3. Perineural treatment with high mobility group box-1 monoclonal antibody prevents initiation of pain-like behaviors in female mice with trigeminal neuropathy, Biological and Pharmaceutical Bulletin, 2024
    Link to Paper Search Results by DOI
  4. Blockade of receptor for advanced glycation end-products with azeliragon ameliorates streptozotocin-induced diabetic neuropathy, Neurochemistry International, 2023
    Link to Paper Search Results by DOI
  5. Mirogabalin alleviates nociceptive hypersensitivity without causing sedation in a mouse model of post-traumatic trigeminal neuropathy, Behavioural Brain Research, 2022
    Link to Paper Search Results by DOI
  6. Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson's disease, Biomedicine & Pharmacotherapy, 2022
    Link to Paper Search Results by DOI
  7. Pretreatment with high mobility group box-1 monoclonal antibody prevents the onset of trigeminal neuropathy in mice with a distal infraorbital nerve chronic constriction injury, Molecules, 2021
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Effect of intranasal treatment with the anti-HMGB1 neutralizing antibody on mechanical hypersensitivity in a mouse model of hemi-Parkinson's disease, Yoki Nakamura, Fumiaki Sato, Simeng Ma, Takahiro Kochi, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Norimitsu Morioka, Society for Neuroscience Annual Meeting, 2022/11/15, Without Invitation, English, San Diego, U.S.A.
  2. Preventive effect of anti-HMGB1 nAb on the onset of distal infraorbital nerve chronic constriction neuropathy in female mice, Simeng Ma, Yoki Nakamura, Takahiro Kochi, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Society for Neuroscience Annual Meeting, 2023/11/13, Without Invitation, English, Washington D.C., U.S.A.
  3. Effect of cannabinoid CB2 agonist on cold hypersensitivity in mice with post-traumatic trigeminal neuropathy, Simeng Ma, Yoki Nakamura, Suzuna Uemoto, Kenta Yamamoto, Kazue Hisaoka-Nakashima, Norimitsu Morioka, CINP-AsCNP 2025 Joint Congress, 2025/06/17, Without Invitation, English, Melbourne, Australia

Awards

  1. 2025/06/17, Student Encouragement Award, CINP-AsCNP 2025 Joint Congress