TOSHIO NAKAMAE

Last Updated :2022/12/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Assistant Professor
E-mail
nakamaethiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Orthopaedic surgery

Research Keywords

  • spine surgery low back pain osteoporotic vertebral fracture sports medicine

Affiliated Academic Societies

  • Japanese society for study of spinal cord function
  • International Society for the Study of the Lumbar Spine (ISSLS)
  • The Japanese Orthopaedic Society for Sports Medicine
  • Japanese Society of Lumbar Spine Disorders
  • THE WESTERN JAPANESE RESEARCH SOCIETY FOR SPINE
  • the Chugoku-Shikoku Orthopaedic Association
  • The Central Japan Journal of Orthopaedic Surgery & Traumatology
  • the Japanese Society for Spine Surgery and Related Research

Educational Activity

Course in Charge

  1. 2022, Undergraduate Education, Year, Clinical diagnosis and treatment II
  2. 2022, Undergraduate Education, Intensive, Practice of Medicine I
  3. 2022, Undergraduate Education, 2Term, Surgery II

Research Activities

Academic Papers

  1. Foramen magnum decompression with resection of outer layer of the dura for Chiari type I malformation: Factors correlated with reduction of syrinx, Asian Spine J., 2022
  2. Development of a rat model with lumbar vertebral endplate lesion, Eur Spine J., 2022
  3. Percutaneous intervertebral-vacuum polymethylmethacrylate injection for foraminal stenosis with degenerative lumbar scoliosis, World Neurosurgery, 2022
  4. Primary malignant melanoma of the spinal cord: a two-case report and literature review, Spine Surg Relat Res., 2022
  5. Quantitative Assessment of Bone Marrow Edema in Adolescent Athletes with Lumbar Spondylolysis Using Contrast Ratio on Magnetic Resonance Imaging, ASIAN SPINE JOURNAL, 15(5), 682-687, 202110
  6. Relationship between clinical symptoms of osteoporotic vertebral fracture with intravertebral cleft and radiographic findings., J Orthop Sci, 22(2), 201-206, 2017
  7. Pathology and Treatment of Traumatic Cervical Spine Syndrome: Whiplash Injury, ADVANCES IN ORTHOPEDICS, 2018
  8. Chondroitinase ABC promotes corticospinal axon growth in organotypic cocultures, Spinal Cord, 47(2), 161-165, 2008
  9. Quantitative assessment of myelopathy patients using motor evoked potentials produced by transcranial magnetic stimulation, Eur Spine J, 19(5), 685-690, 2010
  10. The effect of an external magnetic force on cell adhesion and proliferation of magnetically labeled mesenchymal stem cells, Sports Med Arthrosc Rehabil Ther Technol, 2(1), 5-5, 2010
  11. The effects of combining chondroitinase ABC and NEP1-40 on the corticospinal axon growth in organotypic co-cultures, Neurosci Lett, 476(1), 14-17, 2010
  12. Pharmacological inhibition of TNF may reduce pain behavior changes induced by experimental disc puncture in the rat, Spine, 36(4), 232-236, 2011
  13. The usefulness of motor evoked potentials produced by transcranial magnetic stimulation for the patients with myelopathy, Journal of Spine Research, 2(2), 215-219, 2011
  14. Investigation of segmental motor paralysis after cervical laminoplasty using intraoperative spinal cord monitoring with transcranial electric motor evoked potentials, Journal of spinal disorders and techniques, 25(2), 92-98, 2012
  15. Surgical treatment of high-grade dysplastic spondylolisthesis using intraoperative electrophysiological monitoring: report of two cases and review of the literature, European Journal of Orthopaedic Surgery & Traumatology, 23(1), 121-127, 2013
  16. Percutaneous vertebroplasty for osteoporotic vertebral compression fracture with intravertebral cleft associated with delayed neurologic deficit, European Spine Journal, 22(7), 1624-1632, 2013
  17. Efficacy of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fractures with Intravertebral Cleft, The Open Orthopaedics Journal, 9, 107-113, 2015
  18. Bone Marrow Edema and Low Back Pain in Elderly Degenerative Lumbar Scoliosis: A Cross-sectional Study, Spine, 41(10), 885-892, 2016
  19. Risk factors for cement loosening after vertebroplasty for osteoporotic vertebral fracture with intravertebral cleft: a retrospective analysis, Asian Spine J, 12(5), 935-942, 2017
  20. Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome with destructive spondylitis: a case report, Spine Surgery and Related Research, 2018
  21. Expansive laminoplasty for cervical myelopathy with interconnected porous calcium hydroxyapatite ceramic spacers: comparison with autogenous bone spacers, J Spinal Disord Tech, 21(8), 547-552, 2008
  22. CD133+ cells from human peripheral blood promote corticospinal axon regeneration, Neuroreport, 19(8), 799-803, 2008
  23. Clinical results of cervical myelopathy in patients older than 80 years of age: evaluation of spinal function with motor evoked potentials, J Neurosurg Spine, 11(4), 421-426, 2009
  24. Assessment of central motor conduction time in the diagnosis of compressive thoracic myelopathy, Spine, 35(26), 1593-1598, 2010
  25. CD133+ cells from human umbilical cord blood reduce cortical damage and promote axonalgrowth in neonatal rat organ co-cultures exposed to hypoxia, Int J Dev Neurosci, 28(7), 581-587, 2010
  26. Pain behavior changes following disc puncture relate to nucleus pulposus rather than to the disc injury per se: an experimental study in rats, Open Orthop J, 5, 72-77, 2011
  27. MicroRNA-223 expression in neutrophils in the early phase of secondary damage after spinalcord injury, Neurosci Lett, 492(2), 114-118, 2011
  28. Magnetic Field-based Delivery of Human CD133 Positive Cells Promotes Functional Recovery Following Rat Spinal Cord Injury, Spine, 37(13), 768-777, 2012
  29. Heme oxygenase-1 modulates degeneration of the intervertebral disc after puncture in Bach 1 deficient mice, Eur Spine J, 21(9), 1748-1757, 2012
  30. Long-term clinical results of microsurgical transdural discectomy with laminoplasty: follow-up results over 10 years, J Neurosurg Spine, 18(6), 653-660, 2013
  31. Use of prone position magnetic resonance imaging for detecting the terminal filum in patients with occult tethered cord syndrome, J Neurosurg Spine, 18(1), 76-84, 2013
  32. Medium-term Clinical Results of Microsurgical Lumbar Flavectomy That Preserves Facet Joints in Cases of Lumbar Degenerative Spondylolisthesis: Comparison of Bilateral Laminotomy With Bilateral Decompression by a Unilateral Approach, J Spinal Disord Tech, 26(7), 351-358, 2015
  33. Clinical results of microsurgical bilateral decompression via unilateral approach for lumbar canal stenosis with multiple-level involvement, Eur J Orthop Surg Traumatol, 25(1), 191-198, 2015
  34. Targeted Therapy for Low Back Pain in Elderly Degenerative Lumbar Scoliosis: A Cohort Study, Spine, 41(10), 872-879, 2016
  35. Novel hybrid hydroxyapatite spacers ensure sufficient bone bonding in cervical laminoplasty, Asian Spine Journal, 2018
  36. Novel Hybrid Hydroxyapatite Spacers Ensure Sufficient Bone Bonding in Cervical Laminoplasty, ASIAN SPINE JOURNAL, 12(6), 1078-1084, 201812
  37. Transforaminal percutaneous endoscopic discectomy for lumbar disc herniation in athletes under the local anesthesia, J Orthop Sci, 2019
  38. The correlation between sagittal spinopelvic alignment and degree of lumbar degenerative spondylolisthesis, J Orthop Sci, 2019
  39. Electrophysiological Assessment and Classification of Motor Pathway Function in Patients With Spinal Dural Arteriovenous Fistula, J Clin Neurophysiol, 36(1), 45-51, 201901
  40. Electrophysiological Assessment and Classification of Motor Pathway Function in Patients With Spinal Dural Arteriovenous Fistula, JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 36(1), 45-51, 201901
  41. The correlation between sagittal spinopelvic alignment and degree of lumbar degenerative spondylolisthesis, JOURNAL OF ORTHOPAEDIC SCIENCE, 24(6), 969-973, 201911
  42. Transforaminal percutaneous endoscopic discectomy for lumbar disc herniation in athletes under the local anesthesia, JOURNAL OF ORTHOPAEDIC SCIENCE, 24(6), 1015-1019, 201911
  43. A Case Report of a Japanese Boy with Morquio A Syndrome: Effects of Enzyme Replacement Therapy Initiated at the Age of 24 Months, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(3), 202002
  44. Transforaminal percutaneous endoscopic discectomy for lumbar disc herniation in athletes under the local anesthesia, J Orthop Sci., 24(6), 1015-1019, 2019
  45. Long-Term Outcome of Targeted Therapy for Low Back Pain in Elderly Degenerative Lumbar Scoliosis, Eur Spine J, 30(7), 2020-2032, 2021
  46. Quantitative assessment of bone marrow edema in adolescent athletes with lumbar spondylolysis using contrast ratio on magnetic resonance imaging, Asian Spine J, 2020
  47. Quantifying bone marrow edema adjacent to the lumbar vertebral endplate on magnetic resonance imaging: a cross sectional study of patients with chronic low back pain, Asian Spine J., 2021
  48. Spinous process fractures in osteoporotic vertebral fractures: a cross-sectional study, Spine Surgery and Related Research, 2021
  49. Surgical outcomes of cervical myelopathy in patients with athetoid cerebral palsy, Eur J Orthop Surg Traumatol, 2021

Invited Lecture, Oral Presentation, Poster Presentation

  1. Association of vertebral bone marrow edema with low back pain in degenerative lumbar scoliosis in the elderly, Toshio Nakamae, ISSLS (International Society for the Study of the Lumbar Spine), 2019, Without Invitation, English
  2. Pathology and treatment for cervical flexion myelopathy, Toshio Nakamae, 10th Annual Meeting of Cervical Spine Research Society - Asia Pacific Section, 2019, Without Invitation, English
  3. Treatment for Cervical Myelopathy Associated with Athetoid Cerebral Palsy, Toshio Nakamae, 10th Annual Meeting of Cervical Spine Research Society - Asia Pacific Section, 2019, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

  1. 2021, 2023
  2. 2019, 2020

Social Activities

History as Peer Reviews of Academic Papers

  1. 2021, European Spine Journal
  2. 2021, Scientific Reports
  3. 2021, European Spine Journal
  4. 2021, Spine Surgery and Related Research
  5. 2021, Asian Spine Journal
  6. 2021, Spine Surgery and Related Research
  7. 2021, Asian Spine Journal
  8. 2020, Spine Surgery and Related Research
  9. 2020, Scientific Reports
  10. 2020, Journal of pain research
  11. 2020, Asian Spine Journal
  12. 2020, European Spine Journal
  13. 2020, European Spine Journal
  14. 2015, Osteoporosis International
  15. 2015, Osteoporosis International
  16. 2016, BioMed Research International
  17. 2016, European Spine Journal
  18. 2017, European Spine Journal
  19. 2015, European Spine Journal
  20. 2014, European Spine Journal
  21. 2018, European Spine Journal
  22. 2019, Clinical Interventions in Aging
  23. 2018, PLOS ONE