石井 大典DAISUKE ISHII

Last Updated :2025/04/17

所属・職名
大学院医系科学研究科(保) 教授
メールアドレス
ishiidhiroshima-u.ac.jp
自己紹介
脳損傷後の機能回復を促進する新たな方法の探索を行っています.現在は,半側空間無視モデルマウスを用いた新規治療物質の探索,中枢神経損傷後の感覚障害に対する効果的な介入法の開発研究に取り組んでいます.これらは,回復メカニズムの解明と新たなリハビリテーション介入法の開発を目指すものです.

基本情報

主な職歴

  • 2025年04月, 広島大学, 大学院医系科学研究科, 教授
  • 2022年04月, 2025年03月, 茨城県立医療大学, 保健医療学部作業療法学科, 准教授
  • 2017年10月, 2022年03月, 茨城県立医療大学, 保健医療学部医科学センター, 助教
  • 2017年04月, 2017年09月, 国際医療福祉大学, 成田保健医療学部作業療法学科, 助教
  • 2013年04月, 2017年01月, 木更津病院, 作業療法士
  • 2008年04月, 2013年03月, 介護老人保健施設 秀眉園, 作業療法士

学歴

  • 千葉大学, 大学院医学薬学府, 先端生命科学専攻, 2010年04月, 2013年03月
  • 千葉大学, 大学院医学薬学府 医科学専攻, 2008年04月, 2010年03月
  • 昭和大学, 保健医療学部, 作業療法学科, 2004年04月, 2008年03月

研究分野

  • 複合領域 / 人間医工学 / リハビリテーション科学・福祉工学
  • 医歯薬学 / 基礎医学 / 生理学一般

研究キーワード

  • 半側空間無視モデルマウス、視床出血モデルラット、行動実験、体性感覚、電気生理、体性感覚誘発電位、恐怖記憶

所属学会

  • 日本神経科学学会
  • 日本生理学会
  • 日本作業療法研究学会
  • 脳機能とリハビリテーション研究会
  • 日本作業療法士協会

研究活動

学術論文(★は代表的な論文)

  1. Case Report: Repetitive peripheral magnetic stimulation and task-oriented training improve motor function in chronic severe post-stroke paralysis, Frontiers in Stroke, 4巻, 2025
  2. Age-Related Impact in Illusory Torque Cues Induced by Asymmetric Vibrations, IEEE Transactions on Haptics, 2025
  3. Factors associated with stiff knee gait in patients with knee osteoarthritis., Journal of orthopaedics, 64巻, 2025
  4. The rodent model of unilateral spatial neglect and its clinical applications, Journal of Rehabilitation Neurosciences, 24巻, 2024
  5. Role of the medial agranular cortex in unilateral spatial neglect., Experimental brain research, 242巻, 6号, 2024
  6. Decreased and Improved Movement Abilities in a Case of Myotonic Dystrophy Type 1: Examining Longitudinal Characteristics Based on Repeated Evaluations., Cureus, 16巻, 5号, 2024
  7. Combined Exercise and Education Program: Effect of Smaller Group Size and Longer Duration on Physical Function and Social Engagement among Community-Dwelling Older Adults, The Journal of Aging Research & Lifestyle, 12巻, 2023
  8. Asymmetry of Interhemispheric Connectivity during Rapid Movements of Right and Left Hands: A TMS-EEG Study., Journal of motor behavior, 54巻, 2号, 2022
  9. Effects of short-term upper limb immobilization on sensory information processing and corticospinal excitability., Experimental brain research, 240巻, 7-8号, 2022
  10. Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex Modulates Cognitive Function Related to Motor Execution During Sequential Task: A Randomized Control Study., Frontiers in human neuroscience, 16巻, 2022
  11. Effects of medication and dual tasking on postural sway in Parkinson's disease: A pilot case study, Advanced Robotics, 35巻, 2021
  12. Opposite modulations of corticospinal excitability by intermittent and continuous peripheral electrical stimulation in healthy subjects., Neuroscience letters, 740巻, 2021
  13. Ipsilesional spatial bias after a focal cerebral infarction in the medial agranular cortex: A mouse model of unilateral spatial neglect., Behavioural brain research, 401巻, 2021
  14. A study on the immediate effects of neuromuscular electrical stimulation on the corticospinal tract excitability of the infraspinatus muscle., Journal of back and musculoskeletal rehabilitation, 34巻, 4号, 2021
  15. Experience of After-Effect of Memory Update Reduces Sensitivity to Errors During Sensory-Motor Adaptation Task., Frontiers in human neuroscience, 15巻, 2021
  16. Relationship Between Motor Function, DTI, and Neurophysiological Parameters in Patients with Stroke in the Recovery Rehabilitation unit., Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 30巻, 8号, 2021
  17. Contralateral and Ipsilateral Interactions in the Somatosensory Pathway in Healthy Humans., Frontiers in systems neuroscience, 15巻, 2021
  18. The Progress of the Gait Impairment and Brain Activation in a Patient with Post-stroke Hemidystonia., Physical therapy research, 24巻, 2号, 2021
  19. Gait Training after Stroke with a Wearable Robotic Device: A Case Report of Further Improvements in Walking Ability after a Recovery Plateau., Progress in rehabilitation medicine, 6巻, 2021
  20. Interaction of the Left-Right Somatosensory Pathways in Patients With Thalamic Hemorrhage: A Case Report., Frontiers in human neuroscience, 15巻, 2021
  21. Cathodal tDCS on the motor area decreases the tactile threshold of the distal pulp of the hallux., Neuroscience letters, 719巻, 2020
  22. A Short-Duration Combined Exercise and Education Program to Improve Physical Function and Social Engagement in Community-Dwelling Elderly Adults., International quarterly of community health education, 40巻, 4号, 2020
  23. Successful transcatheter arterial embolization in an asymptomatic patient with primary racemose hemangioma of the bronchial artery., Respiratory medicine case reports, 30巻, 2020
  24. Spondylodiscitis and spinal epidural abscess related to long-term placement of an airway stent for malignant central airway obstruction., Thoracic cancer, 11巻, 8号, 2020
  25. Spontaneous recovery of fear differs among early - late adolescent and adult male mice., The International journal of neuroscience, 129巻, 1号, 2019
  26. Paternal methyl donor deficient diets during development affect male offspring behavior and memory-related gene expression in mice., Developmental psychobiology, 61巻, 1号, 2019
  27. Effect of Visuospatial Attention on the Sensorimotor Gating System., Frontiers in behavioral neuroscience, 13巻, 2019
  28. Development of the fear regulation system from early adolescence to young adulthood in female mice., Neurobiology of learning and memory, 150巻, 2018
  29. Differential effects of high-definition transcranial direct current stimulation on verbal working memory performance according to sensory modality., Neuroscience letters, 687巻, 2018
  30. Transient contribution of left posterior parietal cortex to cognitive restructuring., Scientific reports, 5巻, 2015
  31. An isolated retrieval trial before extinction session does not prevent the return of fear., Behavioural brain research, 287巻, 2015
  32. Sex differences in fear extinction and involvements of extracellular signal-regulated kinase (ERK)., Neurobiology of learning and memory, 123巻, 2015
  33. Longitudinal Follow-Up of Mirror Movements after Stroke: A Case Study., Case reports in neurological medicine, 2015巻, 2015
  34. Effects of memory age and interval of fear extinction sessions on contextual fear extinction., Neuroscience letters, 578巻, 2014
  35. Methyl donor-deficient diet during development can affect fear and anxiety in adulthood in C57BL/6J mice., PloS one, 9巻, 8号, 2014
  36. Perinatal exposure to bisphenol A enhances contextual fear memory and affects the serotoninergic system in juvenile female mice., Hormones and behavior, 63巻, 5号, 2013
  37. No erasure effect of retrieval-extinction trial on fear memory in the hippocampus-independent and dependent paradigms., Neuroscience letters, 523巻, 1号, 2012
  38. Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain., Progress in neuro-psychopharmacology & biological psychiatry, 39巻, 2号, 2012
  39. Enhancement of acoustic prepulse inhibition by contextual fear conditioning in mice is maintained even after contextual fear extinction., Progress in neuro-psychopharmacology & biological psychiatry, 34巻, 1号, 2010
  40. Effects of aripiprazole on MK-801-induced prepulse inhibition deficits and mitogen-activated protein kinase signal transduction pathway., Neuroscience letters, 471巻, 1号, 2010
  41. d-serine enhances extinction of auditory cued fear conditioning via ERK1/2 phosphorylation in mice., Progress in neuro-psychopharmacology & biological psychiatry, 34巻, 6号, 2010