奈女良 昭Akira Namera

Last Updated :2022/12/01

所属・職名
大学院医系科学研究科(医) 教授
メールアドレス
namerahiroshima-u.ac.jp

基本情報

学位

  • 博士(薬学) (広島大学)
  • 薬学修士 (広島大学)

研究分野

  • 医歯薬学 / 社会医学 / 法医学

研究キーワード

  • 生体試料
  • 薬毒物
  • 薬毒物
  • 中毒
  • 分析
  • 単離
  • 迅速検査法
  • 自然毒
  • 薬物

所属学会

  • 日本法中毒学会
  • 国際法中毒学会
  • 日本分析化学会
  • 日本薬学会
  • 日本中毒学会, 1999年

教育活動

授業担当

  1. 2022年, 学部専門, 集中, 社会医学
  2. 2022年, 修士課程・博士課程前期, セメスター(前期), 特別演習
  3. 2022年, 修士課程・博士課程前期, セメスター(後期), 特別演習
  4. 2022年, 修士課程・博士課程前期, セメスター(前期), 特別研究
  5. 2022年, 修士課程・博士課程前期, セメスター(後期), 特別研究
  6. 2022年, 博士課程・博士課程後期, セメスター(前期), 特別演習
  7. 2022年, 博士課程・博士課程後期, セメスター(後期), 特別演習
  8. 2022年, 博士課程・博士課程後期, セメスター(前期), 特別研究
  9. 2022年, 博士課程・博士課程後期, セメスター(後期), 特別研究
  10. 2022年, 修士課程・博士課程前期, セメスター(前期), 臨床法医学概論
  11. 2022年, 博士課程・博士課程後期, 1ターム, 死因究明学
  12. 2022年, 博士課程・博士課程後期, セメスター(前期), 分子中毒学特別演習
  13. 2022年, 博士課程・博士課程後期, セメスター(後期), 分子中毒学特別演習
  14. 2022年, 博士課程・博士課程後期, セメスター(前期), 分子中毒学特別研究
  15. 2022年, 博士課程・博士課程後期, セメスター(後期), 分子中毒学特別研究

研究活動

学術論文(★は代表的な論文)

  1. Facile determination of natural cannabinoids in cannabis products using a conventional fully porous particle column and isocratic high-performance liquid chromatography with diode-array detector, Forensic Toxicology, 40巻, pp. 417-421, 20220527
  2. Comparison of serum and whole blood concentrations in quetiapine overdose cases, FORENSIC TOXICOLOGY, 40巻, 2号, pp. 403-406, 202207
  3. Simple and simultaneous quantification of cyanide, ethanol, and 1-propa- nol in blood by headspace GC-MS/NPD with Deans switch dual detector system, SCIENCE & JUSTICE, 62巻, 2号, pp. 193-202, 202203
  4. 血中向精神薬分析における固相担体カラムを用いた液─液抽出法による前処理の全自動化, 日本法科学技術学会誌, 26巻, pp. 91-102, 20210120
  5. Neural dysfunctions following experimental permanent occlusions of bilateral common carotid arteries cause an increase of rat voluntary alcohol drinking behavior, LEGAL MEDICINE, 51巻, 202107
  6. BIMP affects tubulin structure and causes abnormalities in cell division, LEGAL MEDICINE, 53巻, 202111
  7. Determination of Glyphosate and Glufosinate in Human Serum by MonoSpin TiO Extraction and Liquid Chromatography-Tandem Mass Spectrometry, ACTA CHROMATOGRAPHICA, 32巻, 1号, pp. 10-15, 202004
  8. Simple and reliable method to simultaneously determine urinary 1-and 2-naphthol using in situ derivatization and gas chromatography-mass spectrometry for biological monitoring of naphthalene exposure in occupational health practice, JOURNAL OF OCCUPATIONAL HEALTH, 62巻, 1号, 202004
  9. Direct methyl esterification with 2,2-dimethoxypropane for the simultaneous determination of urinary metabolites of toluene, xylene, styrene, and ethylbenzene by gas chromatography-mass spectrometry, JOURNAL OF OCCUPATIONAL HEALTH, 61巻, 1号, pp. 82-90, 201901
  10. Assessment of Concentrations of Four Phenothiazine Antipsychotics in Serum and Whole Blood Using Different Diatomaceous Earth-based Solid-phase Columns: A Comparative Analysis, ANALYTICAL SCIENCES, 35巻, 7号, pp. 815-819, 201907
  11. High-Throughput MonoSpin Extraction for Quantification of Cardiovascular Drugs in Serum Coupled to High-Performance Liquid Chromatography-Mass Spectrometry, ACTA CHROMATOGRAPHICA, 31巻, 4号, pp. 294-298, 201912
  12. Detection of synthetic cannabinoids using GC-EI-MS, positive GC-CI-MS, and negative GC-CI-MS, INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 131巻, 1号, pp. 143-152, 2017
  13. Optimization and application of octadecyl-modified monolithic silica for solid-phase extraction of drugs in whole blood samples, JOURNAL OF CHROMATOGRAPHY A, 1517巻, pp. 9-17, 2017
  14. A neonatal prolonged QT syndrome due to maternal use of oral tricyclic antidepressants, EUROPEAN JOURNAL OF PEDIATRICS, 175巻, 8号, pp. 1129-1132, 2016
  15. Comprehensive review of the detection methods for synthetic cannabinoids and cathinones, FORENSIC TOXICOLOGY, 33巻, 2号, pp. 175-194, 2015
  16. Evaluation of urinary cyclohexanediols and cyclohexanol as biomarkers of occupational exposure to cyclohexane, JOURNAL OF OCCUPATIONAL HEALTH, 57巻, 4号, pp. 365-370, 2015
  17. Spin column extraction as a new sample preparation method in bioanalysis, BIOANALYSIS, 7巻, 17号, pp. 2171-2176, 2015
  18. A Case of Severe Puffer Fish Poisoning: Serum Tetrodotoxin Concentration Measurements for 4 Days after Ingestion., J Clin Toxicol., 5巻, pp. 226, 2015
  19. Time-course profile of urinary excretion of intravenously administered alpha-pyrrolidinovalerophenone and alpha-pyrrolidinobutiophenone in a human, FORENSIC TOXICOLOGY, 32巻, 1号, pp. 68-74, 2014
  20. Detection of abused drugs in human blood by using the on-site drug-screening device Oratect (R) III, LEGAL MEDICINE, 16巻, 5号, pp. 308-313, 2014
  21. A Method for Routine Analysis of Urinary 4,4 '-methylenebis (2-chloroaniline) by Gas Chromatography-Electron Capture Detection, JOURNAL OF OCCUPATIONAL HEALTH, 56巻, 5号, pp. 347-350, 2014
  22. いわゆる「脱法ドラッグ(危険ドラッグ)関連精神障害における入院時特徴と尿中および毛髪中の脱法新薬の追及」, 日本精神科救急学会誌, 17巻, pp. 28-34, 2014
  23. 室内火災の現場より救出され一酸化炭素中毒を合併したシアン中毒傷病者の一例, 日本救急医学会誌, 25巻, pp. 797-803, 2014
  24. ★, Advances in monolithic materials for sample preparation in drug and pharmaceutical analysis, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 45巻, pp. 182-196, 2013
  25. Recent advances in unique sample preparation techniques for bioanalysis, BIOANALYSIS, 5巻, 8号, pp. 915-932, 2013
  26. ★, Sequential extraction of amphetamines, opiates, and 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid from a limited volume of urine using a monolithic silica spin column coupled with gas chromatography-mass spectrometry, FORENSIC TOXICOLOGY, 31巻, 2号, pp. 312-321, 2013
  27. A fatal case of 3,4-methylenedioxypyrovalerone poisoning: coexistence of alpha-pyrrolidinobutiophenone and alpha-pyrrolidinovalerophenone in blood and/or hair, FORENSIC TOXICOLOGY, 31巻, 2号, pp. 338-343, 2013
  28. A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere, BMC PUBLIC HEALTH, 13巻, 2013
  29. Simple segmental hair analysis for alpha-pyrrolidinophenone-type designer drugs by MonoSpin extraction for evaluation of abuse history, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 942巻, pp. 15-20, 2013
  30. ★, Sequential extraction of inorganic arsenic compounds and methyl arsenate in human urine using mixed-mode monolithic silica spin column coupled with gas chromatography-mass spectrometry, JOURNAL OF SEPARATION SCIENCE, 35巻, 18号, pp. 2506-2513, 201209
  31. Colorimetric detection and chromatographic analyses of designer drugs in biological materials: a comprehensive review, FORENSIC TOXICOLOGY, 29巻, 1号, pp. 1-24, 201101
  32. Monolith as a new sample preparation material: Recent devices and applications, JOURNAL OF SEPARATION SCIENCE, 34巻, 8号, pp. 901-924, 201104
  33. ★, Simultaneous extraction of acidic and basic drugs from urine using mixed-mode monolithic silica spin column bonded with octadecyl and cation-exchange group, JOURNAL OF SEPARATION SCIENCE, 34巻, 16-17号, pp. 2232-2239, 201109
  34. Monolithic silica with HPLC separation and solid phase extraction materials for determination of drugs in biological materials, ANALYTICAL METHODS, 3巻, 10号, pp. 2189-2200, 201110
  35. Extraction of amphetamines and methylenedioxyamphetamines from urine using a monolithic silica disk-packed spin column and high-performance liquid chromatography-diode array detection, JOURNAL OF CHROMATOGRAPHY A, 1208巻, 1-2号, pp. 71-75, 20081024
  36. Miniaturized sample preparation method for determination of amphetamines in urine., Forensic Sci. Int., 143巻, pp. 163-7, 20040401
  37. Monolithic silica capillary column as a new tool for extraction of methamphetamine in urine., Jpn. J Forensic Toxicol., 22巻, pp. 200-4, 20040401
  38. Direct colorimetric method for determination of organophophates in human urine (共著), Clinica Chimica Acta, 291巻, pp. 9-18, 20000401
  39. Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography-mass spectrometry after headspace-solid phase microextraction and derivatization(共著), Forensic Science International, 109巻, pp. 215-223, 20000401
  40. Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography - mass spectrometry after headspace-solid phase microextraction and derivatization., Forensic Sci. Int., 109巻, 3号, pp. 215-223, 20000401
  41. Direct colorimetric method for determination of organophosphates in human urine., Clin Chim Acta, 291巻, 1号, pp. 9-18, 20000401
  42. Simple and sensitive analysis of nereistoxin and its metabolites in human serum using headspace solid-phase microextraction and gas chromatography-mass spectrometry, J. Chromatogr. Sci., 37巻, 3号, pp. 77-82, 19990401
  43. 法中毒学における固相マイクロ抽出(SPME)法, Jpn. J Forensic Toxicol., 16巻, 1号, pp. 1-15, 19980401
  44. Simple analysis of local anaesthetics in human blood using headspace-silod phase microextraction and gas chromatography-mass spectrometer/electron impact ionization-selected ion monitoring(GC-MS/EI-SIM), J. Chromatogr. B, 709巻, 2号, pp. 225-232, 19980401
  45. Simple analysis of tetracyclic antidepressants in blood using headspace solid-phase microextraction and GC-MS, J. Anal. Toxicol., 22巻, pp. 396-400, 19980401
  46. 乱用薬物スクリーニングキットTriageの臨床的有用性の評価-第2報-, 医学と薬学, 40巻, 1号, pp. 175-180, 19980401
  47. 乱用薬物スクリーニングキット Triage の臨床的有用性の評価?第2報?, pp. 175-180, 19980401
  48. 乱用薬物スクリーニングキットTriageの臨床的有用性の評価, 医学と薬学, 37巻, 3号, pp. 723-731, 19970401
  49. Triage TMによるアンフェタミン類の検出における問題点, 法医学の実際と研究, 40巻, pp. 99-102, 19970401
  50. Rapid quantitative analysis of oleandrin in human blood by high-performance liquid chromatography., Jpn. J. Legal Med., 51巻, 4号, pp. 315-318, 19970401

著書等出版物

  1. 2019年03月01日, Sample Preparation in LC-MS Bioanalysis, Monolithic Spin Column Ectraction in LC-MS Bioanalysis, 2019年, 03, 単行本(学術書), 共著, 978-1-119-27429-2, 400, 163-173
  2. 2018年, Chromatographic Techniques in the Forensic Analysis of Designer Drugs, Mass Spectrometric Analysis Applied for the Determination of Synthetic Cannabinoids, CRC Press, Taylor & Francis Group, 2018年, 2018, 単行本(学術書), 共著, 478, 235-250
  3. 2017年, Recent Advances in Analytical Techniques, Recent advances in unique sample preparation techniques for biological and environmental analysis, Bentham Science Publishers, 2017年, 2017, 単行本(学術書), 共著, 300, 1-53
  4. 2014年, Analytical detection of arsenic species in enviromental and biological materials., Nova Science Publishers, 2014年, 単行本(学術書), 共著, English, 152, 47-66
  5. 2007年12月, Drug and Alcohol Abuse Research Focus - Chromatographic Determination of Methamphetamine and Amphetamine Analogues in Human Urine and Blood - , NOVA Science Publishers= Inc., 2007年, 12, 単行本(学術書), 共著, 中本晃弘 西田まなみ 屋敷 幹雄 , 1600218083, 189
  6. 2006年06月, New Research on Methamphetamine Abuse - Single Hair and Segmental Analysis of Methamphetamine and Amphetamine - , NOVA Science Publishers= Inc., 2006年, 06, 単行本(学術書), 共著, 西田まなみ 屋敷幹雄 , 1600213782, 182

社会活動

委員会等委員歴

  1. 編集委員, 2016年07月, 2018年06月, 日本中毒学会
  2. 理事, 2017年07月, 2020年06月, 日本法中毒学会