Akira Namera

Last Updated :2025/07/15

Affiliations, Positions
Graduate School of Biomedical and Health Sciences, Professor
E-mail
namerahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Pharmaceutical Science, Hiroshima University
  • Master of Pharmaceutical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Society medicine;Legal medicine

Research Keywords

  • separation
  • biological materials
  • drugs
  • poisoning
  • Analysis
  • drugs
  • simple analysis
  • natural toxin
  • Drugs

Affiliated Academic Societies

  • Japanese Association of Forensic Toxocology
  • The International Association of Forensic Toxicoloists
  • The Japan Society for Analytical Chemistry
  • The Pharmaceutical Society of Japan
  • The Japanese Society of Clinical Toxicology, 1999

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Intensive, Social Medicine
  2. 2025, Graduate Education (Master's Program) , First Semester, Seminar
  3. 2025, Graduate Education (Master's Program) , Second Semester, Seminar
  4. 2025, Graduate Education (Master's Program) , First Semester, Research
  5. 2025, Graduate Education (Master's Program) , Second Semester, Research
  6. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  7. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  8. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  9. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  10. 2025, Graduate Education (Master's Program) , First Semester, Lecture on Clinical Forensic Medicine
  11. 2025, Graduate Education (Doctoral Program) , 1Term, Cause of Death Investigation
  12. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on forensic Toxicology
  13. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on forensic Toxicology
  14. 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on forensic Toxicology
  15. 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on forensic Toxicology

Research Activities

Academic Papers

  1. Identification of an unidentified corpse with gingival overgrowth: A case report, LEGAL MEDICINE, 75, 202505
  2. A fatal intoxication case due to the serotonin syndrome induced by dextromethorphan and moclobemide overdose, LEGAL MEDICINE, 74, 202504
  3. Relationship between childhood caries and social background: Regarding the novel emerged correlation between induced abortion and dental caries, PEDIATRIC DENTAL JOURNAL, 35(1), 202504
  4. Electrocardiographic changes in severe quetiapine poisoning, CLINICAL TOXICOLOGY, 63(2), 139-141, 20250201
  5. Early diagnosis of nonconvulsive status epilepticus due to lithium intoxication using 6-channel electroencephalography, CANADIAN JOURNAL OF EMERGENCY MEDICINE, 26(12), 899-902, 202412
  6. Urinary benzyl alcohol and hippuric acid in workers exposed to benzyl alcohol during paint-stripping work, JOURNAL OF OCCUPATIONAL HEALTH, 66(1), 20241114
  7. Pharmacobezoar Associated Prolonged Clinical Course in a Patient with Immediate Release Quetiapine Overdose, JOURNAL OF MEDICAL TOXICOLOGY, 20(4), 430-433, 202410
  8. Giant T waves and QT interval prolongation associated with guanfacine toxicity, CLINICAL TOXICOLOGY, 62(4), 269-271, 20240402
  9. Refractory seizures due to severe quetiapine poisoning, Clinical Toxicology, 61(8), 620-621, 20230901
  10. Unexpected refractory hypotension following intradermal minoxidil injection, Clinical Toxicology, 61(4), 319-320, 20230329
  11. Curent on-site urinalysis testing for drug abuse 2, The Japanese Journal of Clinical Toxicology, 36(1), 51-54, 20230310
  12. QT-Interval Prolongation Associated with Supratherapeutic Guanfacine Concentration: A Case Report, JOURNAL OF MEDICAL TOXICOLOGY, 20(2), 218-221, 202404
  13. Unexpectedly Prolonged Serotonin Syndrome and Fatal Complications Following a Massive Overdose of Paroxetine Controlled-Release, CUREUS JOURNAL OF MEDICAL SCIENCE, 15(12), e5061, 20231217
  14. Detection of lisdexamfetamine and its metabolite d-amphetamine in urine and gastric contents collected from a cadaver at forensic autopsy, FORENSIC TOXICOLOGY, 41(2), 309-317, 202307
  15. Left Stellate Ganglion Blockade for Refractory Ventricular Arrhythmias With Aconitine Poisoning: A Case Report, A & A PRACTICE, 17(2), e01666, 202302
  16. A method for determining valproic acid in human whole blood and urine via gas chromatography-mass spectrometry and small-scale inter-laboratory trial, LEGAL MEDICINE, 59, 20221110
  17. Facile determination of natural cannabinoids in cannabis products using a conventional fully porous particle column and isocratic high-performance liquid chromatography with diode-array detector, Forensic Toxicology, 40, 417-421, 20220527
  18. Comparison of serum and whole blood concentrations in quetiapine overdose cases, FORENSIC TOXICOLOGY, 40(2), 403-406, 20220731
  19. Simple and simultaneous quantification of cyanide, ethanol, and 1-propa- nol in blood by headspace GC-MS/NPD with Deans switch dual detector system, SCIENCE & JUSTICE, 62(2), 193-202, 20220320
  20. Neural dysfunctions following experimental permanent occlusions of bilateral common carotid arteries cause an increase of rat voluntary alcohol drinking behavior, LEGAL MEDICINE, 51, 202107
  21. BIMP affects tubulin structure and causes abnormalities in cell division, LEGAL MEDICINE, 53, 202111
  22. Determination of Glyphosate and Glufosinate in Human Serum by MonoSpin TiO Extraction and Liquid Chromatography-Tandem Mass Spectrometry, ACTA CHROMATOGRAPHICA, 32(1), 10-15, 202004
  23. Simple and reliable method to simultaneously determine urinary 1-and 2-naphthol using in situ derivatization and gas chromatography-mass spectrometry for biological monitoring of naphthalene exposure in occupational health practice, JOURNAL OF OCCUPATIONAL HEALTH, 62(1), 202004
  24. Direct methyl esterification with 2,2-dimethoxypropane for the simultaneous determination of urinary metabolites of toluene, xylene, styrene, and ethylbenzene by gas chromatography-mass spectrometry, JOURNAL OF OCCUPATIONAL HEALTH, 61(1), 82-90, 201901
  25. Assessment of Concentrations of Four Phenothiazine Antipsychotics in Serum and Whole Blood Using Different Diatomaceous Earth-based Solid-phase Columns: A Comparative Analysis, ANALYTICAL SCIENCES, 35(7), 815-819, 201907
  26. High-Throughput MonoSpin Extraction for Quantification of Cardiovascular Drugs in Serum Coupled to High-Performance Liquid Chromatography-Mass Spectrometry, ACTA CHROMATOGRAPHICA, 31(4), 294-298, 201912
  27. Detection of synthetic cannabinoids using GC-EI-MS, positive GC-CI-MS, and negative GC-CI-MS, INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 131(1), 143-152, 2017
  28. Optimization and application of octadecyl-modified monolithic silica for solid-phase extraction of drugs in whole blood samples, JOURNAL OF CHROMATOGRAPHY A, 1517, 9-17, 2017
  29. A neonatal prolonged QT syndrome due to maternal use of oral tricyclic antidepressants, EUROPEAN JOURNAL OF PEDIATRICS, 175(8), 1129-1132, 2016
  30. Comprehensive review of the detection methods for synthetic cannabinoids and cathinones, FORENSIC TOXICOLOGY, 33(2), 175-194, 2015
  31. Evaluation of urinary cyclohexanediols and cyclohexanol as biomarkers of occupational exposure to cyclohexane, JOURNAL OF OCCUPATIONAL HEALTH, 57(4), 365-370, 2015
  32. Spin column extraction as a new sample preparation method in bioanalysis, BIOANALYSIS, 7(17), 2171-2176, 2015
  33. A Case of Severe Puffer Fish Poisoning: Serum Tetrodotoxin Concentration Measurements for 4 Days after Ingestion., J Clin Toxicol., 5, 226, 2015
  34. Time-course profile of urinary excretion of intravenously administered alpha-pyrrolidinovalerophenone and alpha-pyrrolidinobutiophenone in a human, FORENSIC TOXICOLOGY, 32(1), 68-74, 2014
  35. Detection of abused drugs in human blood by using the on-site drug-screening device Oratect (R) III, LEGAL MEDICINE, 16(5), 308-313, 2014
  36. A Method for Routine Analysis of Urinary 4,4 '-methylenebis (2-chloroaniline) by Gas Chromatography-Electron Capture Detection, JOURNAL OF OCCUPATIONAL HEALTH, 56(5), 347-350, 2014
  37. ★, Advances in monolithic materials for sample preparation in drug and pharmaceutical analysis, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 45, 182-196, 2013
  38. Recent advances in unique sample preparation techniques for bioanalysis, BIOANALYSIS, 5(8), 915-932, 2013
  39. ★, Sequential extraction of amphetamines, opiates, and 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid from a limited volume of urine using a monolithic silica spin column coupled with gas chromatography-mass spectrometry, FORENSIC TOXICOLOGY, 31(2), 312-321, 2013
  40. A fatal case of 3,4-methylenedioxypyrovalerone poisoning: coexistence of alpha-pyrrolidinobutiophenone and alpha-pyrrolidinovalerophenone in blood and/or hair, FORENSIC TOXICOLOGY, 31(2), 338-343, 2013
  41. A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere, BMC PUBLIC HEALTH, 13, 2013
  42. Simple segmental hair analysis for alpha-pyrrolidinophenone-type designer drugs by MonoSpin extraction for evaluation of abuse history, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 942, 15-20, 2013
  43. ★, Sequential extraction of inorganic arsenic compounds and methyl arsenate in human urine using mixed-mode monolithic silica spin column coupled with gas chromatography-mass spectrometry, JOURNAL OF SEPARATION SCIENCE, 35(18), 2506-2513, 201209
  44. Colorimetric detection and chromatographic analyses of designer drugs in biological materials: a comprehensive review, FORENSIC TOXICOLOGY, 29(1), 1-24, 201101
  45. Monolith as a new sample preparation material: Recent devices and applications, JOURNAL OF SEPARATION SCIENCE, 34(8), 901-924, 201104
  46. ★, Simultaneous extraction of acidic and basic drugs from urine using mixed-mode monolithic silica spin column bonded with octadecyl and cation-exchange group, JOURNAL OF SEPARATION SCIENCE, 34(16-17), 2232-2239, 201109
  47. Monolithic silica with HPLC separation and solid phase extraction materials for determination of drugs in biological materials, ANALYTICAL METHODS, 3(10), 2189-2200, 201110
  48. Extraction of amphetamines and methylenedioxyamphetamines from urine using a monolithic silica disk-packed spin column and high-performance liquid chromatography-diode array detection, JOURNAL OF CHROMATOGRAPHY A, 1208(1-2), 71-75, 20081024
  49. Miniaturized sample preparation method for determination of amphetamines in urine., Forensic Sci. Int., 143, 163-7, 20040401
  50. Monolithic silica capillary column as a new tool for extraction of methamphetamine in urine., Jpn. J Forensic Toxicol., 22, 200-4, 20040401
  51. Simple and simultaneous analysis of fenfluramine, amphetamine and methamphetamine in whole blood by gas chromatography - mass spectrometry after headspace-solid phase microextraction and derivatization., Forensic Sci. Int., 109(3), 215-223, 20000401
  52. Direct colorimetric method for determination of organophosphates in human urine., Clin Chim Acta, 291(1), 9-18, 20000401
  53. Simple and sensitive analysis of nereistoxin and its metabolites in human serum using headspace solid-phase microextraction and gas chromatography-mass spectrometry, J. Chromatogr. Sci., 37(3), 77-82, 19990401
  54. Solid phase microextraction in forensic toxicology, Jpn. J Forensic Toxicol., 16(1), 1-15, 19980401
  55. Simple analysis of local anaesthetics in human blood using headspace-silod phase microextraction and gas chromatography-mass spectrometer/electron impact ionization-selected ion monitoring(GC-MS/EI-SIM), J. Chromatogr. B, 709(2), 225-232, 19980401
  56. Simple analysis of tetracyclic antidepressants in blood using headspace solid-phase microextraction and GC-MS, J. Anal. Toxicol., 22, 396-400, 19980401
  57. Clinical evaluation of Triage for drugs of abuse : the second report, Jpn. J. Med. Pharm. Sci, 40(1), 175-180, 19980401
  58. Clinical evaluation of Triage for drugs of abuse, Igaku to Yakugaku, 37(3), 723-731, 19970401
  59. Some problems of detecting amphetamines in biological materials by using Triage TM, Res. Pract. Forens. Med., 40, 99-102, 19970401
  60. Rapid quantitative analysis of oleandrin in human blood by high-performance liquid chromatography., Jpn. J. Legal Med., 51(4), 315-318, 19970401

Publications such as books

  1. 2023/08/01, Standard Protocols on Mass Spectrometry, 2023, 8, Scholarly Book, Joint work, 日本語, Akira Namera, 353, 348-353
  2. 2019/03/01, Sample Preparation in LC-MS Bioanalysis, Monolithic Spin Column Ectraction in LC-MS Bioanalysis, John Wiley & Sons, Inc., 2019, 03, Scholarly Book, Joint work, 978-1-119-27429-2, 400, 163-173
  3. 2018, Chromatographic Techniques in the Forensic Analysis of Designer Drugs, Mass Spectrometric Analysis Applied for the Determination of Synthetic Cannabinoids, CRC Press, Taylor & Francis Group, 2018, 2018, Scholarly Book, Joint work, 478, 235-250
  4. 2017, Recent Advances in Analytical Techniques, Recent advances in unique sample preparation techniques for biological and environmental analysis, Bentham Science Publishers, 2017, 2017, Scholarly Book, Joint work, 300, 1-53
  5. 2014, Analytical detection of arsenic species in enviromental and biological materials., Nova Science Publishers, 2014, Scholarly Book, Joint work, English, Akira Namera, Akita Takeuchi, 152, 47-66
  6. 2007/12, Drug and Alcohol Abuse Research Focus - Chromatographic Determination of Methamphetamine and Amphetamine Analogues in Human Urine and Blood - , NOVA Science Publishers= Inc., 2007, 12, Scholarly Book, Joint work, 1600218083, 189
  7. 2006/06, New Research on Methamphetamine Abuse - Single Hair and Segmental Analysis of Methamphetamine and Amphetamine - , NOVA Science Publishers= Inc., 2006, 06, Scholarly Book, Joint work, 1600213782, 182

Invited Lecture, Oral Presentation, Poster Presentation

  1. Examination of recombinant hydrolysis enzymes for rapid screening of metabolites in urine, Akira Namera, The 42th Annual Meeting of the Japanese Associaton of Forensic Toxicology, 2023/06/29, Without Invitation, Japanese

Awards

  1. 2004/04, The 5th Young Scientist Award of Japanese Association of Forensic Toxicology (Yoshimura Prize), Microextraction of illicit drugs and agricultural chemicals in biological matrials

Patented

  1. Patent, JP3783055, 2006/03/24
  2. Patent, JP3658621, 2005/03/25
  3. Patent, JP2952359, 1999/07/16
  4. Patent

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2023, 2025
  2. 2003
  3. 2007
  4. 2007
  5. KAKENHI, 2014, 2016
  6. KAKENHI, Research for non-cholinergic toxicity of a sarin-like organophosphate on animal cardiovascular system., 2008, 2010
  7. KAKENHI, Hair has known the history of drugs abused, 2007, 2010
  8. KAKENHI, 2007, 2010
  9. KAKENHI, High throughput analysis of illegal drugs and medicines using monolith column for extraction from biological materials, 2003, 2006
  10. KAKENHI, 2002, 2004
  11. KAKENHI, 2001, 2002
  12. KAKENHI, 1999, 2000
  13. 2016/04, 2019/03
  14. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  15. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2020, 2022

Social Activities

History as Committee Members

  1. Chief Editor, 2023/01, 2024/07, Forensit Toxicology