秋 庸裕Tsunehiro Aki

Last Updated :2021/02/01

所属・職名
大学院統合生命科学研究科 教授
ホームページ
メールアドレス
akihiroshima-u.ac.jp
その他連絡先
東広島市鏡山一丁目3番1号 先端科学総合研究棟608N
TEL:082-424-7755 FAX:082-424-7755

基本情報

主な職歴

  • 2001年10月01日, 2007年03月31日, 広島大学, 大学院先端物質科学研究科, 助教授
  • 1994年04月01日, 1996年03月31日, 米国National Institutes of Health, 博士研究員
  • 1996年04月01日, 2001年09月30日, 広島大学, 工学部, 助手
  • 2007年04月01日, 2014年08月31日, 広島大学, 大学院先端物質科学研究科, 准教授
  • 2014年09月01日, 2019年03月31日, 広島大学, 大学院先端物質科学研究科, 教授
  • 2019年04月01日, 広島大学, 大学院統合生命科学研究科, 教授

学歴

  • 広島大学, 大学院工学研究科, 工業化学専攻, 1989年04月, 1994年03月
  • 広島大学, 工学部, 第三類(化学系), 1985年04月, 1989年03月

学位

  • 博士(工学) (広島大学)

教育担当

  • 【学士課程】 工学部 : 第三類(応用化学・生物工学・化学工学系)
  • 【博士課程前期】 統合生命科学研究科 : 統合生命科学専攻 : 生物工学プログラム
  • 【博士課程後期】 統合生命科学研究科 : 統合生命科学専攻 : 生物工学プログラム

研究分野

  • 農学 / 農芸化学 / 応用微生物学
  • 工学 / プロセス・化学工学 / 生物機能・バイオプロセス

教育活動

授業担当

  1. 2020年, 学部専門, セメスター(後期), 基礎化学実験
  2. 2020年, 学部専門, 2ターム, 基礎工業概論
  3. 2020年, 学部専門, 3ターム, 酵素化学
  4. 2020年, 学部専門, 集中, 食品プロセス工学II
  5. 2020年, 学部専門, セメスター(後期), 生物工学討論
  6. 2020年, 修士課程・博士課程前期, 1ターム, 生命科学概論
  7. 2020年, 修士課程・博士課程前期, セメスター(前期), 分子生命機能科学セミナー
  8. 2020年, 修士課程・博士課程前期, セメスター(後期), 分子生命機能科学セミナー
  9. 2020年, 修士課程・博士課程前期, 1ターム, 生物工学特別演習A
  10. 2020年, 修士課程・博士課程前期, 2ターム, 生物工学特別演習A
  11. 2020年, 博士課程・博士課程後期, 1ターム, 生命科学研究計画法
  12. 2020年, 修士課程・博士課程前期, 2ターム, 細胞機能科学A
  13. 2020年, 修士課程・博士課程前期, 1ターム, 生命科学概論
  14. 2020年, 修士課程・博士課程前期, 年度, 生物工学演習
  15. 2020年, 修士課程・博士課程前期, 年度, 生物工学演習
  16. 2020年, 修士課程・博士課程前期, 3ターム, 生物工学特別演習B
  17. 2020年, 修士課程・博士課程前期, 4ターム, 生物工学特別演習B
  18. 2020年, 修士課程・博士課程前期, 年度, 生物工学特別研究
  19. 2020年, 博士課程・博士課程後期, 年度, 統合生命科学特別研究

研究活動

学術論文(★は代表的な論文)

  1. Direct detection of mRNA expression in microbial cells by fluorescence in situ hybridization using RNase H-assisted rolling circle amplification, SCIENTIFIC REPORTS, 10巻, 1号, 20200615
  2. Complete genome sequence of Nitratireductor sp. strain OM-1: A lipid-producing bacterium with potential use in wastewater treatment, Biotechnology Reports, 24巻, pp. e00366, 20190809
  3. Marine Oomycetes (Halophytophthora and Salispina): A Potential Source of Fatty Acids with Cytotoxic Activity Against Breast Adenocarcinoma Cells (MCF7), JOURNAL OF OLEO SCIENCE, 68巻, 12号, pp. 1163-1174, 2019
  4. Growth and fatty acid profiles of Halophytophthora vesicula and Salispina spinosa from Philippine mangrove leaves, LETTERS IN APPLIED MICROBIOLOGY, 69巻, 3号, pp. 221-228, 201909
  5. Metabolite Profile Analysis of Aurantiochytrium limacinum SR21 Grown on Acetate-based Medium for Lipid Fermentation, JOURNAL OF OLEO SCIENCE, 68巻, 6号, pp. 541-549, 201906
  6. A Possible Trifunctional beta-Carotene Synthase Gene Identified in the Draft Genome of Aurantiochytrium sp Strain KH105, GENES, 9巻, 4号, 201804
  7. RNase H-assisted RNA-primed rolling circle amplification for targeted RNA sequence detection, SCIENTIFIC REPORTS, 8巻, 20180517
  8. Isolation of High Carotenoid-producing Aurantiochytrium sp Mutants and Improvement of Astaxanthin Productivity Using Metabolic Information, JOURNAL OF OLEO SCIENCE, 67巻, 5号, pp. 571-578, 201805
  9. Efficient conversion of mannitol derived from brown seaweed to fructose for fermentation with a thraustochytrid, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 125巻, 2号, pp. 180-184, 201802
  10. Prominent IgE-binding and cytokine-inducing capacities of a newly cloned N-terminal region of Der f 14, an apolipophorin-like house dust mite allergen, JOURNAL OF BIOCHEMISTRY, 163巻, 1号, pp. 51-60, 201801
  11. Improved methanization and microbial diversity during batch mode cultivation with repetition of substrate addition using defined organic matter and marine sediment inoculum at seawater salinity, BIORESOURCE TECHNOLOGY, 245巻, pp. 833-840, 201712
  12. Der f 35: An MD-2-like house dust mite allergen that cross-reacts with Der f 2 and Pso o 2, ALLERGY, 72巻, 11号, pp. 1728-1736, 201711
  13. Quantitative In Situ Mass Spectrometry Analysis of Mannitol Decomposition Products under Hydrothermal Conditions, ENERGY & FUELS, 31巻, 10号, pp. 10866-10873, 201710
  14. Real-Time Mass Spectrometric Analysis of Hydrothermal Reaction Products, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 56巻, 36号, pp. 9993-9998, 20170913
  15. Growth and Fatty Acid Production of Halophytophthora S13005YL1-3.1 under Different Salinity and pH Levels, PHILIPPINE AGRICULTURAL SCIENTIST, 100巻, pp. S6-S11, 201707
  16. 海藻カロテノイドと不飽和脂肪酸代謝, 化学と生物, 54巻, 5号, pp. 308-309, 201605
  17. 吸入性抗原:最近の進歩/ダニアレルゲン, アレルギー・免疫, 24巻, pp. 28-33, 2016
  18. 海藻バイオマスの利用とラビリンチュラによる油脂生産, 海洋と生物, 38巻, 1号, pp. 36-40, 201601
  19. 海洋大型藻類からのエネルギー・マテリアル回収, 環境バイオテクノロジー学会誌, 16巻, 1号, pp. 3-9, 201601
  20. In situ mass spectrometry of glucose decomposition under hydrothermal reactions, KOREAN JOURNAL OF CHEMICAL ENGINEERING, 34巻, 5号, pp. 1524-1530, 201705
  21. In-situ Mass Spectroscopic Analysis of Glucose Decomposition under Hydrothermal Condition: Quantitative Analysis for Reaction Kinetics, JOURNAL OF THE JAPAN PETROLEUM INSTITUTE, 60巻, 2号, pp. 101-109, 201703
  22. Decomposition kinetics of uronic acids obtained from kelp under hydrothermal condition, JOURNAL OF THE ENERGY INSTITUTE, 90巻, 2号, pp. 185-190, 201704
  23. Der f 34, a Novel Major House Dust Mite Allergen Belonging to a Highly Conserved Rid/YjgF/YER057c/UK114 Family of Imine Deaminases, JOURNAL OF BIOLOGICAL CHEMISTRY, 291巻, 41号, pp. 21607-21615, 20161007
  24. Decomposition Kinetics of Mannose, Its Sugar Alcohol, and Its Uronic Acid under Hydrothermal Condition, JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 49巻, 7号, pp. 663-667, 201607
  25. Kinetics of Sorbitol Decomposition under Hydrothermal Condition, JOURNAL OF THE JAPAN PETROLEUM INSTITUTE, 59巻, 4号, pp. 149-154, 201607
  26. Bacterial community structure and predicted alginate metabolic pathway in an alginate-degrading bacterial consortium, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 121巻, 3号, pp. 286-292, 201603
  27. Detection of Acyl-CoA Derivatized with Butylamide for in vitro Fatty Acid Desaturase Assay, JOURNAL OF OLEO SCIENCE, 65巻, 2号, pp. 161-167, 201602
  28. High-rate Fermentation of Acetate to Methane under Saline Condition by Aceticlastic Methanogens Immobilized in Marine Sediment, PEDIATRIC NEUROLOGY, 55巻, pp. 9-15, 201602
  29. Characterization of a halotolerant acetoclastic methanogen highly enriched from marine sediment and its application in removal of acetate, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 121巻, 2号, pp. 196-202, 201602
  30. Identification of amino acid residues that determine the substrate specificity of mammalian membrane-bound front-end fatty acid desaturases, JOURNAL OF LIPID RESEARCH, 57巻, 1号, pp. 89-99, 201601
  31. Semi-continuous methane production from undiluted brown algae using a halophilic marine microbial community, BIORESOURCE TECHNOLOGY, 200巻, pp. 616-623, 201601
  32. Isolation and characterization of bacterium producing lipid from short-chain fatty acids, BIORESOURCE TECHNOLOGY, 201巻, pp. 215-221, 201602
  33. Effect of Salinity on Propionate Degradation by Acclimated Marine Sediments, APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 177巻, 7号, pp. 1541-1552, 201512
  34. Dysgonomonas alginatilytica sp nov., an alginate-degrading bacterium isolated from a microbial consortium, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 65巻, pp. 3570-3575, 201510
  35. Improved methane production from brown algae under high salinity by fed-batch acclimation, BIORESOURCE TECHNOLOGY, 187巻, pp. 275-281, 201507
  36. Determination of Mannitol Decomposition Rate under Hydrothermal Pretreatment Condition, JOURNAL OF THE JAPAN PETROLEUM INSTITUTE, 58巻, 4号, pp. 252-255, 201507
  37. Behavior of organics in kelp during hydrothermal pretreatment: Fundamental characteristics and effect of salt, J. Jpn. Inst. Energy, 93巻, 5号, pp. 531-535, 201405
  38. Enzymatic Analysis of Positional Distribution of Fatty Acids in Solid Fat by 1,3-Selective Transesterification with Candida antarctica Lipase B, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 91巻, 8号, pp. 1323-1330, 201408
  39. Evaluation of marine sediments as microbial sources for methane production from brown algae under high salinity, BIORESOURCE TECHNOLOGY, 169巻, pp. 362-366, 201410
  40. Regulation of Polyunsaturated Fatty Acid Biosynthesis by Seaweed Fucoxanthin and Its Metabolite in Cultured Hepatocytes, LIPIDS, 49巻, 2号, pp. 133-141, 201402
  41. Value-added lipid production from brown seaweed biomass by two-stage fermentation using acetic acid bacterium and thraustochytrid, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 98巻, 22号, pp. 9207-9216, 201411
  42. Unexpected T cell regulatory activity of anti-histone H1 autoantibody: Its mode of action in regulatory T cell-dependent and -independent manners, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 431巻, 2号, pp. 246-252, 20130208
  43. Utilization of Waste Syrup for Production of Polyunsaturated Fatty Acids and Xanthophylls by Aurantiochytrium, JOURNAL OF OLEO SCIENCE, 62巻, 9号, pp. 729-736, 201309
  44. Prophylactic effect of Lactobacillus oral vaccine expressing a Japanese cedar pollen allergen, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 113巻, 4号, pp. 536-541, 201204
  45. Fermented sake lees with lactic acid bacteria prevents allergic rhinitis-like symptoms and IgE-mediated basophil degranulation, Biosci. Biotechnol. Biochem., 20110301
  46. Metabolism and Synthesis of Lipids in the Polyunsaturated Fatty Acid-Producing Fungus Mortierella alliacea, JOURNAL OF OLEO SCIENCE, 60巻, 1号, pp. 11-17, 201101
  47. Purification and characterization of intracellular lipase from the polyunsaturated fatty acid-producing fungus Mortierella alliacea, NEW BIOTECHNOLOGY, 28巻, 2号, pp. 158-164, 20110228
  48. Sake Lees Fermented with Lactic Acid Bacteria Prevents Allergic Rhinitis-Like Symptoms and IgE-Mediated Basophil Degranulation, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 75巻, 1号, pp. 140-144, 201101
  49. Simultaneous thermogravimetry and differential thermal analysis for comparing burning characteristics between oleaginous and non-oleaginous microorganisms, THERMOCHIMICA ACTA, 517巻, 1-2号, pp. 115-120, 20110420
  50. Thermal analysis for differentiating between oleaginous and non-oleaginous microorganisms, BIOCHEMICAL ENGINEERING JOURNAL, 57巻, pp. 23-29, 20111115
  51. アレルゲンによる上皮細胞からのTSLP産生誘導, 臨床免疫・アレルギー科, 56巻, 5号, pp. 473-477, 20111101
  52. 微粉砕コンニャクグルコマンナンの抗炎症作用, 生物機能研究, 15巻, pp. 44-47, 20111101
  53. A New Lipid Transfer Protein Homolog Identified as an IgE-Binding Antigen from Japanese Cedar Pollen, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 74巻, 3号, pp. 504-509, 201003
  54. Enhanced production of squalene in the thraustochytrid Aurantiochytrium mangrovei by medium optimization and treatment with terbinafine, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 26巻, 7号, pp. 1303-1309, 201007
  55. Molecular cloning and immunochemical characterization of a new Japanese cedar pollen allergen homologous to plant subtilisin-like serine protease., World Allergy Organization J., 3巻, 11号, pp. 262-265, 20101101
  56. Molecular Cloning and Immunochemical Characterization of a Novel Major Japanese Cedar Pollen Allergen Belonging to the Aspartic Protease Family, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 152巻, 3号, pp. 207-218, 2010
  57. Optimization of nitrogen source for enhanced production of squalene from thraustochytrid Aurantiochytrium sp., NEW BIOTECHNOLOGY, 27巻, 4号, pp. 382-389, 20100930
  58. アレルギーワクチンの創製, 化学と生物, 48巻, 7号, pp. 453-455, 20100701
  59. Improvement of Stearidonic Acid Production in Oleaginous Saccharomyces cerevisiae, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73巻, 6号, pp. 1447-1449, 200906
  60. Isolation and immunochemical characterization of native Der f 17, a new class of EF-hand calcium-binding allergen from the house dust mite, Dermatophagoides farinae., Proceedings of the World Allergy Congress 2009, 20090101
  61. Oral vaccination of lactic acid bacteria expressing a major allergen prevents nasal symptoms and IgE response in a murine model of cedar pollinosis, Proceedings of the World Allergy Congress 2009, 20090101
  62. Screening and Characterization of Squalene-Producing Thraustochytrids from Hong Kong Mangroves, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 57巻, 10号, pp. 4267-4272, 20090527
  63. Development of a two-step chromatography procedure that allows the purification of a high-purity anti-histone H1 monoclonal immunoglobulin M antibody with immunosuppressant activity, BIOMEDICAL CHROMATOGRAPHY, 22巻, 1号, pp. 13-19, 200801
  64. アレルギーワクチンの開発に向けて, バイオインダストリー, 25巻, 9号, pp. 69-77, 20080901
  65. Dietary pulverized konjac glucomannan prevents the development of allergic rhinitis-like symptoms and IgE response in mice, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71巻, 10号, pp. 2551-2556, 200710
  66. Dietary pulverized konjac glucomannan suppresses scratching behavior and skin inflammatory immune responses in NC/Nga mice, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 144巻, 2号, pp. 95-104, 2007
  67. Heterologous production of dihomo-gamma-linolenic acid in Saccharomyces cerevisiae, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73巻, 21号, pp. 6965-6971, 200711
  68. Nutritional enrichment of larval fish feed with thraustochytrid producing polyunsaturated fatty acids and xanthophylls, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 104巻, 3号, pp. 200-206, 200709
  69. Anti-histone H1 autoantibody directly acts on T cells to exert its immunosuppressive activity., Animal Cell Technology: Basic & Applied Aspects, 15巻, IN PRESS号, 20060925
  70. Decrease in the allergenicity of Japanese cedar pollen allergen by treatment with positive and negative cluster ions, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 141巻, 4号, pp. 313-321, 2006
  71. Utilization of shochu distillery wastewater for production of polyunsaturated fatty acids and xanthophylls using thraustochytrid, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 102巻, 4号, pp. 323-327, 200610
  72. プロテオーム解析によるスギ花粉・ダニアレルゲンの全容解明, アレルギー・免疫, 13巻, pp. 340-344, 20060301
  73. A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: Its oral intake suppresses spontaneously occurring dermatitis in NC/Nga mice, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 136巻, 3号, pp. 258-265, 2005
  74. Characterization of immunosuppressive factors expressed in serum by rat tolerogenic liver transplantation, TRANSPLANTATION PROCEEDINGS, 37巻, 1号, pp. 80-81, 2005
  75. Molecular cloning of a class IV chitinase allergen from Japanese cedar (Cryptomeria japonica) pollen and competitive inhibition of its immunoglobulin E-binding capacity by latex C-serum, CLINICAL AND EXPERIMENTAL ALLERGY, 35巻, 2号, pp. 234-243, 200502
  76. イオン処理によるダニアレルゲンのアレルゲン性の低減化, アレルギーの臨床, 25巻, pp. 818-822, 20051001
  77. ダニアレルゲン-分子種構成、分子多型、ならびに特異的免疫治療-, アレルギー科, 19巻, pp. 549-556, 20050601
  78. 海洋微生物による有用脂質の生産と応用, Foods & Food Ingredients Journal of Japan, 210巻, pp. 758-764, 20050801
  79. ★, 高度不飽和脂肪酸の生合成と生産に関する研究, オレオサイエンス, 5巻, pp. 589-599, 20051201
  80. Liver transplantation-induced antihistone H1 autoantibodies suppress mixed lymphocyte reaction, TRANSPLANTATION, 77巻, 10号, pp. 1595-1603, 20040527
  81. The ability of konjac-glucomannan to suppress spontaneously occurring dermatitis in NC/Nga mice depends upon the particle size, BIOFACTORS, 21巻, 1-4号, pp. 163-166, 2004
  82. Two-dimensional IgE-binding spectrum of Japanese cedar (Cryptomeria japonica) pollen allergens, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 133巻, 2号, pp. 125-135, 2004
  83. 海洋微生物ラビリンチュラと脂質工学, 生物工学会誌, 82巻, pp. 288, 20040701
  84. 次世代スギ花粉症診断および治療技術の開発, 化学工業, 55巻, pp. 48-55, 20040101
  85. 乳酸菌L137株におけるアレルゲン遺伝子の発現―経口減感作療法を目指して―, 生物工学会誌, 82巻, pp. 434-435, 20040901
  86. cDNA cloning and functional expression of alpha-glucosidase from Mortierella alliacea, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 62巻, 2-3号, pp. 202-209, 200308
  87. Differential response to low temperature of two Delta 6 fatty acid desaturases from Mucor circinelloides, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 62巻, 4号, pp. 362-368, 200309
  88. Evidence of isozymes for Delta 6 fatty acid desaturase in rat hepatocytes, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 67巻, 2号, pp. 451-454, 200302
  89. Extracellular secretion of free fatty acids by disruption of a fatty acyl-CoA synthetase gene in Saccharomyces cerevisiae, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 95巻, 5号, pp. 435-440, 200305
  90. Grouping newly isolated docosahexaenoic acid-producing thraustochytrids based on their polyunsaturated fatty acid profiles and comparative analysis of 18S rRNA genes, MARINE BIOTECHNOLOGY, 5巻, 5号, pp. 450-457, 2003
  91. Thraustochytrid as a potential source of carotenoids, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 80巻, 8号, pp. 789-794, 200308
  92. 微生物によるカロテノイドの生産, オレオサイエンス, 3巻, pp. 175-181, 20030401
  93. A high-molecular-weight mite antigen (HM1) fraction aggravates airway hyperresponsiveness of allergic mice to house dusts and whole mite cultures, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 129巻, 3号, pp. 204-211, 200211
  94. Analysis of immunosuppressive factors expressed in serum of liver transplanted rats., Animal Cell Technology: Basic & Applied Aspects, 12巻, pp. 257-261, 20020401
  95. Der f 16: a novel gelsolin-related molecule identified as an allergen from the house dust mite, Dermatophagoides farinae, FEBS LETTERS, 516巻, 1-3号, pp. 234-238, 20020410
  96. Enzyme preparation of glycerides rich in docosahexaenoic acid from Thraustochytrid single cell oils by Candida rugosa Lipase., J. Oleo Sci., 51巻, pp. 447-455, 20020401
  97. Gamma-linolenic acid suppresses IgE production in vitro as well as in vivo., Animal Cell Technology: Basic & Applied Aspects, 12巻, pp. 461-465, 20020401
  98. Identification and expression of a rat fatty acid elongase involved in the biosynthesis of C18 fatty acids, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66巻, 3号, pp. 613-621, 200203
  99. Identification of differentially expressed genes in atopic dermatitis-prone NC/Nga mouse., Animal Cell Technology: Basic & Applied Aspects, 12巻, pp. 379-383, 20020401
  100. Inducing proliferative response of T cell on high-molecular-size antigen in Dermatophagoides farinae feces., Int. Archives Allergy Immunol, 127巻, pp. 127、276-284, 20020501
  101. Induction of a proliferative response of T cells by a high-molecular antigen in Dermatophagoides farinae feces, INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 127巻, 4号, pp. 276-284, 200204
  102. Molecular cloning and characterization of a new Japanese cedar pollen allergen homologous to plant isoflavone reductase family, CLINICAL AND EXPERIMENTAL ALLERGY, 32巻, 7号, pp. 1064-1070, 200207
  103. Purification and characterization of a novel fungal alpha-glucosidase from Mortierella alliacea with high starch-hydrolytic activity, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66巻, 11号, pp. 2415-2423, 200211
  104. Toward elucidating the full spectrum of mite allergens - State of the art, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 94巻, 4号, pp. 285-298, 200210
  105. スギ花粉,ダニ抗原の分子種構成と分子多型, アレルギー科, 14巻, pp. 275-284, 20020401
  106. Immunosuppressive autoreactive antibodies induced by liver transplantation., Scandinavian Journal of Immunology, 54巻, S1号, pp. 109, 20010401
  107. Lack of effect of the abnormal fatty acid metabolism in NC/Nga mice on their atopic dermatitis, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 65巻, 2号, pp. 431-434, 200102
  108. Production of arachidonic acid by filamentous fungus, Mortierella alliacea strain YN-15, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 78巻, 6号, pp. 599-604, 200106
  109. Production of polyunsaturated fatty acids by genetic engineering of yeast., J. Oleo Sci., 50巻, 5号, pp. 359-365, 20010501
  110. Profile of polyunsaturated fatty acids produced by Thraustochytrium sp KK17-3, JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 78巻, 6号, pp. 605-610, 200106
  111. ラビリンチュラ類における高度不飽和脂肪酸の生合成機構, 海洋と生物, 23巻, pp. 46-51, 20010201
  112. 高度不飽和脂肪酸の生合成:脂肪酸修飾酵素とその利用, 科学と工業, 75巻, pp. 61-66, 20010201
  113. Newly described house dust mite allergens., Allergy Clin. Immunol. Int., (Suppl.) 1巻, pp. 74-76, 20001001
  114. Purification and characterization of sea squirt alpha-N-acetylgalactosaminidase, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 89巻, 1号, pp. 84-86, 200001
  115. T-cell epitope analysis of Mag 3, an important allergen from the house dust mite, Dermatophagoides farinae, IMMUNOLOGY LETTERS, 72巻, 1号, pp. 53-60, 20000403
  116. 脂肪酸不飽和化系と融合酵素, 化学と生物, 38巻, pp. 520-527, 20000801
  117. 哺乳類のΔ-6脂肪酸不飽和化酵素:その遺伝子クローニングと生理学的意義, 油化学, 49巻, pp. 3-10, 20000101
  118. A newly identified allergen p29, the C-terminal fragment of Cry j 1, induces potently conjunctival congestion of patients with cedar pollenosis., The 9th Tohwa University International Symposium, pp. 271-274, 19990401
  119. Cloning and expression of Der f 6, a serine protease allergen from the house dust mite, Dermatophagoides farinae., Biochim= Biophys. Acta, 1454巻, pp. 201-7, 19990401
  120. Molecular cloning and functional characterization of rat Delta-6 fatty acid desaturase., Biochem. Biophys. Res. Commun., 255巻, 3号, pp. 575-579, 19990201
  121. Purification and characterization of M-177, a 177 kD allergen, from the house dust mite, Dermatophagoides farinae., Allergol. Int., 48巻, pp. 43-51, 19990101
  122. Altered antigenicity of M-177, a 177-KDa allergen from the house dust mite, Dermatophagoides farinae, in stored extract., Clin. Exp. Allergy, 28巻, pp. 1549-58, 19980401
  123. Lipid composition of a newly isolated polyunsaturated fatty acid-producing fungus, Achlya sp. ma-2801., J. Ferment. Bioeng., 86巻, 5号, pp. 504-507, 19981101
  124. Transcription regulation by repressosome and by RNA polymerase contact., Cold Spring Harbor Symp. Quant. Biol., 62巻, pp. 1-10, 19980401
  125. Atomic force microscopic demonstration of DNA looping by GalR and HU., Nucl. Acids Res., 25巻, pp. 873-876, 19970201
  126. Identification on T-cell epitope sequences on an important mite antigen, Clin. Exp. Allergy, 27巻, pp. 1086-94, 19970401
  127. Repression and activation of promoter-bound RNA polymerase by Gal repressor., J. Mol. Biol., 272巻, pp. 293-300, 19970901
  128. Repressor induced site-specific binding of HU for transcriptional regulation., EMBO J., 16巻, pp. 3666-3674, 19970601
  129. Cloning and characterization of a new allergen, Mag3, from the house dust mite, Dermatophagoides farinae: Cross-reactivity with high-molocular-weight allergen., Mol. Immunol., 33巻, pp. 311-319, 19960401
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著書等出版物

  1. リンの事典, 朝倉書店, 2017年, 事典・辞書, 共編著, 大竹久夫他編
  2. バイオマスエネルギーの技術と市場, 藻類の分子育種とその応用, シーエムシー出版, 2016年, 単行本(学術書), 共著, 冷牟田修一, 秋 庸裕
  3. 微細藻類によるエネルギー生産と事業展望-石油業界からみたバイオマスエネルギー, シーエムシー出版, 2012年, 07, 単行本(学術書), 共編著, 9784781306575, 261
  4. 機能性脂質を生産する海洋微生物ラビリンチュラ類の機能開発と応用, 財団法人日本水産油脂協会, 2011年, 01, 単行本(学術書), 単著, 19
  5. Biocatalysis and Biomolecular Engineering, John Wiley & Sons, Inc., 2010年, 05, 単行本(学術書), 共編著, 9780470487594, 490
  6. 油脂・脂質の基礎と応用,改訂第2版, 社団法人 日本油化学会, 2009年, 04, 単行本(学術書), 編著
  7. Biocatalysis and Biotechnology for Functional Foods and Industrial Products , CRC Press, 2006年, 12, 単行本(学術書), 共著
  8. 油脂・脂質の基礎と応用 , 日本油化学会, 2005年, 04, 単行本(学術書), 共編著
  9. Handbook of Industrial Biocatalysis , CRC Press, 2005年, 04, 単行本(学術書), 共著
  10. Fatty acid-modifying enzymes: imprications for industrial applications. , CRC Press= Taylor & Fransis Group, 2005年, 01, 単行本(学術書), 共著, 秋 庸裕 河本 正次 S. Shigeta 小埜 和久
  11. 油化学辞典 , 丸善, 2004年, 03, 事典・辞書, 共編著, 阿部正彦
  12. 機能性脂質のフロンティア , シーエムシー, 2004年, 12, 単行本(学術書), 共編著
  13. 生物工学実験書 , 培風館, 2002年, 04, 単行本(学術書), 共編著
  14. 機能性脂質の新展開 , シーエムシー, 2001年, 01, 単行本(学術書), 共編著, 289
  15. 油化学便覧 , 丸善, 2001年, 11, 単行本(学術書), 共編著, 686

招待講演、口頭・ポスター発表等

  1. 2019年09月19日, 招待, 日本語
  2. 2019年09月13日, 通常, 英語
  3. 2019年08月30日, 招待, 英語
  4. Gas-to-lipids bioprocessing by acetogens and thraustochytrids, 2019年05月06日, 招待, 英語

受賞

  1. 2005年03月, 日本油化学会進歩賞, 高度不飽和脂肪酸の生合成と生産に関する研究
  2. 2004年11月, 日本油化学会オレオサイエンス賞, 微生物によるカロテノイドの生産
  3. 2004年09月, 日本農芸化学会中四国支部奨励賞, 不飽和脂肪酸の代謝,生理機能及び微生物生産に関する研究

取得

  1. 特許権, 特許第6351328号, 2018年06月15日, 高付加価値脂質の生産方法
  2. 特許権, 特許第6553411号, 2019年07月12日, 微生物、炭化水素の生産方法、廃液の処理方法及び微生物のスクリーニング方法
  3. 特許権, 特許第6639858号, 2020年01月07日, 成分分析方法

社会活動

委員会等委員歴

  1. 日本生物工学会脂質駆動産業創生研究部会 幹事, 2019年04月
  2. Biocatalysis and Agricultural Biotechnology 編集委員, 2016年01月
  3. 日本生物工学会西日本支部 評議員, 2015年04月
  4. 日本油化学会 英文誌編集委員, 2008年04月
  5. 日本油化学会 国際交流委員, 2005年04月
  6. 日本農芸化学会中四国支部 参与, 2001年04月

学術会議等の主催

  1. The 15th International Symposium on Biocatalysis and Agricultural Biotechnology, Local Chair, 2019年09月