島田 裕士HIROSHI SHIMADA

Last Updated :2024/12/02

所属・職名
大学院統合生命科学研究科 准教授
メールアドレス
hshimadahiroshima-u.ac.jp

基本情報

主な職歴

  • 1995年04月01日, 1997年10月20日, キリンビール(株), 基盤技術研究所, 研究員
  • 1997年11月01日, 1999年03月31日, 東京工業大学, 生命理工学部生体機構学科生体光反応学講座, 助手
  • 1999年04月01日, 2000年03月31日, 東京工業大学, 生命理工学部生命科学科生体光反応学講座, 助手
  • 2000年04月01日, 2008年09月15日, 東京工業大学, 大学院生命理工学研究科生体システム専攻情報・形態形成学講座, 助手
  • 2008年09月16日, 2019年03月31日, 広島大学, 大学院理学研究科, 准教授

学歴

  • 東京工業大学, 大学院総合理工学研究科, 生命化学専攻博士課程, 日本, 1991年04月, 1994年06月
  • 九州大学, 大学院理学研究科, 生物学専攻修士課程, 日本, 1989年04月, 1991年03月
  • 九州大学, 理学部, 生物学科, 日本, 1985年04月, 1989年03月

学位

  • 博士(理学) (東京工業大学)
  • 理学修士 (九州大学)

研究分野

  • 農学 / 農芸化学 / 植物栄養学・土壌学

教育活動

授業担当

  1. 2024年, 学部専門, 2ターム, 生物科学概説A
  2. 2024年, 教養教育, 2ターム, 教養ゼミ
  3. 2024年, 学部専門, 4ターム, 植物生理学B
  4. 2024年, 学部専門, セメスター(後期), 分子形質発現学演習
  5. 2024年, 学部専門, セメスター(前期), 卒業研究
  6. 2024年, 学部専門, セメスター(後期), 卒業研究
  7. 2024年, 学部専門, セメスター(前期), 生物科学基礎実験I
  8. 2024年, 学部専門, セメスター(前期), 生物科学基礎実験III
  9. 2024年, 学部専門, セメスター(後期), 生物科学基礎実験IV
  10. 2024年, 学部専門, 3ターム, 生物学実験A
  11. 2024年, 修士課程・博士課程前期, 1ターム, 生命理学概論
  12. 2024年, 修士課程・博士課程前期, 年度, 数理生命科学特別研究
  13. 2024年, 修士課程・博士課程前期, 2ターム, 生命理学特論C
  14. 2024年, 修士課程・博士課程前期, 4ターム, 生命理学特論D
  15. 2024年, 修士課程・博士課程前期, 4ターム, 分子形質発現学
  16. 2024年, 修士課程・博士課程前期, セメスター(前期), 生命理学特別演習A
  17. 2024年, 修士課程・博士課程前期, セメスター(後期), 生命理学特別演習B
  18. 2024年, 修士課程・博士課程前期, 4ターム, ゲノム機能学概論

研究活動

学術論文(★は代表的な論文)

  1. Orange protein, phytoene synthase regulator, has protein disulfide reductase activity, PLANT SIGNALING & BEHAVIOR, 17巻, 1号, 20221231
  2. Arabidopsis BSD2 reveals a novel redox regulation of Rubisco physiology in vivo, PLANT SIGNALING & BEHAVIOR, 15巻, 4号, 20200402
  3. Overexpression of BUNDLE SHEATH DEFECTIVE 2 improves the efficiency of photosynthesis and growth in Arabidopsis, PLANT JOURNAL, 102巻, 1号, pp. 129-137, 202004
  4. Dynamics of the leaf endoplasmic reticulum modulate beta-glucosidase-mediated stress-activated ABA production from its glucosyl ester, JOURNAL OF EXPERIMENTAL BOTANY, 71巻, 6号, pp. 2058-2071, 20200325
  5. pCYOs: Binary vectors for simple visible selection of transformants using an albino-cotyledon mutant in Arabidopsis thaliana, PLANT BIOTECHNOLOGY, 36巻, 1号, pp. 39-42, 201903
  6. A new carotenoid, 6-hydroxy-3-didehydrolutein, produced by recombinant Escherichia coli that expresses the violaxanthin biosynthesis and chaperone AtCYO1 genes—its structure and antioxidant activities., Phytochem. Lett., 35巻, pp. 113-118, 2019
  7. Direct measurement of intercellular CO2 concentration in a gas-exchange system resolves overestimation using the standard method, JOURNAL OF EXPERIMENTAL BOTANY, 69巻, 8号, pp. 1981-1991, 2018
  8. Overexpression of the protein disulfide isomerase AtCYO1 in chloroplasts slows dark-induced senescence in Arabidopsis, BMC PLANT BIOLOGY, 18巻, 2018
  9. Disruption of ureide degradation affects plant growth and development during and after transition from vegetative to reproductive stages., BMC Plant Biology, 18巻, pp. 1-16, 2018
  10. Allantoin, a stress-related purine metabolite, can activate jasmonate signaling in a MYC2-regulated and abscisic acid-dependent manner, JOURNAL OF EXPERIMENTAL BOTANY, 67巻, 8号, pp. 2519-2532, 2016
  11. Rice CYO1, an ortholog of Arabidopsis thaliana cotyledon chloroplastbiogenesis factor AtCYO1, is expressed in leaves and involved in photosynthetic performance, JOURNAL OF PLANT PHYSIOLOGY, 207巻, pp. 78-83, 2016
  12. In vitro and in vivo evidence for oxalate oxidase activity of a germin-like protein from azalea, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 458巻, 3号, pp. 536-542, 2015
  13. (6E) and (6Z)-9 '-Aporhodoxanthinone, novel carotenoids produced in zeaxanthin-synthesizing-Escherichia coli by redox stress, TETRAHEDRON LETTERS, 56巻, 44号, pp. 6063-6065, 2015
  14. The purine metabolite allantoin enhances abiotic stress tolerance through synergistic activation of abscisic acid metabolism, PLANT CELL AND ENVIRONMENT, 37巻, 4号, pp. 1022-1036, 2014
  15. Arabidopsis xanthine dehydrogenase mutants defective in purine degradation show a compromised protective response to drought and oxidative stress., Plant Biteochnology, 31巻, pp. 173-178, 2014
  16. Arabidopsis cotyledon chloroplast biogenesis factor CYO1 uses glutathione as an electron donor and interacts with PSI (A1 and A2) and PSII (CP43 and CP47) subunits, JOURNAL OF PLANT PHYSIOLOGY, 169巻, 12号, pp. 1212-1215, 2012
  17. RNA interference-mediated suppression of xanthine dehydrogenase reveals the role of purine metabolism in drought tolerance in Arabidopsis, FEBS LETTERS, 584巻, 6号, pp. 1181-1186, 2010
  18. Chloroplast biogenesis during the early stage of leaf development in rice, PLANT BIOTECHNOLOGY, 27巻, 1号, pp. 85-90, 2010
  19. Contribution of chloroplast biogenesis to carbon-nitrogen balance during early leaf development in rice, JOURNAL OF PLANT RESEARCH, 123巻, 4号, pp. 617-622, 2010
  20. Normalization using ploidy and genomic DNA copy number allows absolute quantification of transcripts, proteins and metabolites in cells, PLANT METHODS, 6巻, 2010
  21. Arabidopsis cotyledon-specific chloroplast biogenesis factor CYO1 is a protein disulfide isomerase, Plant Cell, 19巻, pp. 3157-3169, 2007
  22. Isolation of SIP, a protein that interacts with SPB, a possible transcriptional regulatory factor in Rhodobacter sphaeroides., Plant Cell Physiology, 48巻, pp. 1504-1508, 2007
  23. Identification of a novel cis-element exhibiting cytokinin-dependent protein binding in vitro in the 5’-region of NADPH-protochlorophyllide oxidoreductase gene in cucumber., Plant Mol. Biol., 59巻, pp. 631-645, 2005
  24. Inactivation and deficiency of core proteins of photosystems I and II caused by genetical phylloquinone and plastoquinone deficiency but retained lamellar structure in a T-DNA mutant of Arabidopsis., Plant J., 41巻, pp. 627-637, 2005
  25. ARC3, a chloroplast division factor, is a chimera of prokaryotic FtsZ and part of eukaryotic phosphatigylinositol-4-phosphate 5-kinase., Plant Cell Physiology, 45巻, pp. 960-967, 2004
  26. Distinctive features of plant organs characterized by global analysis of gene expression in Arabidopsis., DNA Res., 11巻, pp. 11-25, 2004
  27. Digalactosyldiacylglycerol is a major glycolipid in floral organs of Petunia hybrida., Lipids, 38巻, pp. 1107-1112, 2003
  28. Functional analysis of isoforms of NADPH:protochlorophyllide oxidoreductase (POR), PORB and PORC, in Arabidopsis thaliana., Plant Cell Physiology, 44巻, pp. 963-974, 2003
  29. Light and cytokinin play a cooperative role in MGDG synthesis in greening cucumber cotyledons., Plant Cell Physiology, 44巻, pp. 844-855, 2003
  30. Chlorophyllase as a serine hydrolase: Identification of a putative catalytic triad., Plant Cell Physiology, 44巻, pp. 96-101, 2003
  31. Production of active bovine cathepsin C (dipeptidyl aminopeptidase I) in the methylotrophic yeast Candida boidinii., Appl. Micorobial. Biotech., 59巻, pp. 252-258, 2002
  32. Identification of two differentially regulated isoforms of protochlorophyllide oxidoreductase (POR) from tobacco revealed a wide variety of light- and development-dependent regulations of POR gene expression among angiosperms., Photosynth. Res., 74巻, pp. 165-172, 2002
  33. Two types of ferrochelatase in photosynthetic and non-photosynthetic tissues of cucumber; their difference in phylogeny, gene expression and localization., J. Biol. Chem., 277巻, pp. 4731-4737, 2002
  34. Two distinct isopentenyl diphosphate isomerases in cytosol and plastid are differentially induced by environmental stresses in tobacco., FEBS Lett., 506巻, pp. 61-64, 2001
  35. Two types of MGDG synthase genes, found widely in both "16:3" and "18:3" plants, differentially mediate galactolipid syntheses in photosynthetic and non-photosynthetic tissues in Arabidopsis thaliana., Proc. Natl. Acad. Sci. USA, 98巻, pp. 10960-10965, 2001
  36. An Arabidopsis sigma factor (SIG2)-dependent expression of plastid-encoded tRNAs in chloroplasts., Plant Cell Physiology, 42巻, pp. 1034-1043, 2001
  37. Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: Self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways., DNA Res., 8巻, pp. 153-161, 2001
  38. Accumulation of plant galactolipid affects cell morphology of Escherichia coli., Biochem. Biophys. Res. Commun., 286巻, pp. 114-118, 2001
  39. Isolation of protease component from maize cysteine protease-cystatin complex: Release of cystatin is not crucial for the activation of the cysteine protease., Plant Cell Physiology, 42巻, pp. 710-716, 2001
  40. A Cysteine Protease from maize isolated in a complex with cystatin., Plant Cell Physiology, 42巻, pp. 185-191, 2000
  41. Overexpression, enzymatic properties and localization of a ferrochelatase of cucumber., Plant Cell Physiology, 42巻, pp. 192-199, 2000
  42. Chloroplast development in Arabidopsis thaliana requires the nuclear-encoded transcription factor sigma B., FEBS Lett., 485巻, pp. 178-182, 2000
  43. NADPH-protochlorophyllide oxidoreductase in cucumber is encoded by a single gene and its expression is transcriptionally enhanced by illumination., Photosynth. Res., 64巻, pp. 147-154, 2000
  44. Identification of a novel light-inducible isoform of NADPH-protochlorophyllide oxidoreductase from Arabidopsis thaliana., FEBS Lett., 474巻, pp. 133-136, 2000
  45. A novel cysteine protease from maize isolated in a complex with cystatin., Plant Cell Physiology, 41巻, pp. 185-191, 2000
  46. Photosynthetic regulatory gene cluster in an aerobic photosynthetic bacterium, Roseobacter denitrificans., J. Gen. Appl. Microbiol., 45巻, pp. 129-134, 1999
  47. Magnesium insertion by magenesium chelatase in the biosynthesis of zinc-bacteriochlorophyll a in an aerobic acidophilic bacterium Acidiphilium rubrum., J. Biol. Chem., 274巻, pp. 33594-33600, 1999
  48. Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate., Proc. Natl. Acad. Sci. USA, 96巻, pp. 15362-15367, 1999
  49. Increased caroteniod production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway., Appl. Environ. Microb., 64巻, pp. 2676-2680, 1998
  50. Production of the carotenoids lycopene, ß-carotene and astaxanthin in the food yeast Candida utilis., Appl. Environ. Microb., 64巻, pp. 1226-1229, 1998
  51. Production of lycopene by the food yeast, Candida utilis that dose not Naturally synthesize carotenoid., Biochenol. Bioeng., 58巻, pp. 306-308, 1998
  52. Enzymatic confirmation of reactions involved in routes to astaxanthin formation, elucidated using a direct substrate in vitro assay., Eur. J. Biochem., 252巻, pp. 229-236, 1998
  53. Growth, pigmentation, and expression of the puf and puc operons in a light-responding-repressor (SPB)-disrupted Rhodobacter sphaeroides., Plant Cell Physiology, 39巻, pp. 411-417, 1998
  54. Nucleotide sequence and transcriptional analysis of the flanking region of the gene(spb) for the trans-acting factor that controls light-mediated expression of the puf operon in Rhodobacter sphaeroides., Plant Cell Physiology, 38巻, pp. 558-567, 1997
  55. Expression of the puf operon in an aerobic photosynthetic bacterium, Roseobacter denitrificans., Plant Cell Physiology, 37巻, pp. 153-159, 1996
  56. A transcription factor with a leucine-zipper motif involved in light-dependent inhibition of expression of the puf operon in the photosynthetic bacterium Rhodobacter sphaeroides., Plant Cell Physiology, 37巻, pp. 515-522, 1996
  57. A putative transcription factor binding to the upstream region of the puf operon in Rhodobacter sphaeroides., FEBS Lett., 382巻, pp. 41-44, 1993
  58. Inhibition of accumulation of bacteriochlorophyll and carotenoids by blue light in aerobic photosynthetic bacterium, Roseobacter denitrificans, during anaerobic respiration., Plant Cell Physiology, 33巻, pp. 1171-1174, 1992
  59. Blue-light irradiation reduces the expression of puf and puc operon of Rhodobacter sphaeroides under semi-aerobic conditions., Plant Cell Physilogy, 33巻, pp. 471-475, 1992

取得

  1. 特許権, 6114580, 2017年03月24日, イネ形質転換体及びその作製方法

外部資金

競争的資金等の採択状況

  1. 挑戦的研究(萌芽), 光合成を標的としたケミカルバイオロジーによる植物成長促進剤の開発研究, 2022年
  2. 科学研究費助成事業(基盤研究(B)), 二酸化炭素固定化酵素Rubiscoの酸化失活・分解の生理生態学的意義の再定義, 2021年
  3. 先端的低炭素化技術開発事業(ALCA), 植物の光合成活性を高める技術の開発, 2015年11月01日, 2020年03月31日
  4. 研究成果展開事業(A-STEP), 光合成の明反応と暗反応それぞれの機能強化による植物バイオマス増加, 2012年11月01日, 2013年10月31日
  5. 科学研究費助成事業(基盤研究(C)), 酸素酸化によるルビスコの失活を防ぐメカニズムの解明, 2014年, 2016年
  6. 科学研究費助成事業(基盤研究(C)), 子葉と本葉において異なる葉緑体形成機構の解析, 2008年, 2010年
  7. 科学研究費助成事業(基盤研究(C)), ゲノム情報・遺伝子発現プロファイルと逆遺伝学を利用した葉緑体分裂制御機構の解明, 2006年, 2007年
  8. 科学研究費助成事業(若手研究(B)), 葉緑体分裂制御因子ARC3と(被)制御因子の機能解析による葉緑体形成機構の解明, 2004年, 2005年
  9. 科学研究費助成事業(基盤研究(C)), 好酸性光合成細菌におけるクロロフィル中心金属の亜鉛への置換機構, 2000年, 2001年
  10. 科学研究費助成事業(基盤研究(B)), Two-component制御システムによる光合成細菌の光合成遺伝子発現調節, 1989年, 1999年
  11. 先端的低炭素化技術開発事業(ALCA), 植物の光合成活性を高める技術の開発, 2015年11月01日, 2019年03月31日
  12. 先端的低炭素化技術開発事業(ALCA), 植物の光合成活性を高める技術の開発, 2015年11月01日, 2020年03月31日