Last Updated :2024/04/03

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor

Basic Information

Major Professional Backgrounds

  • 1995/04/01, 1997/10/20, Kirin Brewery Company, Limited, Researcher
  • 1997/11/01, 1999/03/31, Tokyo Institute of Technology, Research Associate
  • 1999/04/01, 2000/03/31, Tokyo Institute of Technology, Research Associate
  • 2000/04/01, 2008/09/15, Tokyo Institute of Technology, Research Associate
  • 2008/09/16, 2019/03/31, Hiroshima University, Graduate School of Science, Associate Professor

Educational Backgrounds

  • Tokyo Institute of Technology, Japan, 1991/04, 1994/06
  • Kyushu University, Japan, 1989/04, 1991/03
  • Kyushu University, Japan, 1985/04, 1989/03

Academic Degrees

  • Doctor of Science, Tokyo Institute of Technology
  • Master of Science, Kyushu University

Research Fields

  • Agricultural sciences;Agricultural chemistry;Plant nutrition / Soil science

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 2Term, Introduction to Biological Sciences A
  2. 2024, Liberal Arts Education Program1, 2Term, Introductory Seminar for First-Year Students
  3. 2024, Undergraduate Education, 4Term, Plant Physiology B
  4. 2024, Undergraduate Education, Second Semester, Seminar for Molecular Plant Biology
  5. 2024, Undergraduate Education, First Semester, Special Study for Graduation
  6. 2024, Undergraduate Education, Second Semester, Special Study for Graduation
  7. 2024, Undergraduate Education, First Semester, Practice for Fundamental Biology I
  8. 2024, Undergraduate Education, First Semester, Practice for Fundamental Biology III
  9. 2024, Undergraduate Education, Second Semester, Practice for Fundamental Biology IV
  10. 2024, Undergraduate Education, 3Term, Laboratory Work in Biology A
  11. 2024, Graduate Education (Master's Program) , 1Term, Introduction to Life Science
  12. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Mathematical and Life Sciences
  13. 2024, Graduate Education (Master's Program) , 2Term, Topical Seminar in Life Science A
  14. 2024, Graduate Education (Master's Program) , 4Term, Topical Seminar in Life Science B
  15. 2024, Graduate Education (Master's Program) , 4Term, Molecular Plant Biology
  16. 2024, Graduate Education (Master's Program) , First Semester, Exercises in Life Science A
  17. 2024, Graduate Education (Master's Program) , Second Semester, Exercises in Life Science B
  18. 2024, Graduate Education (Master's Program) , 4Term, Introduction to Genetics and Genomics

Research Activities

Academic Papers

  1. Orange protein, phytoene synthase regulator, has protein disulfide reductase activity, PLANT SIGNALING & BEHAVIOR, 17(1), 20221231
  2. Arabidopsis BSD2 reveals a novel redox regulation of Rubisco physiology in vivo, PLANT SIGNALING & BEHAVIOR, 15(4), 20200402
  3. Overexpression of BUNDLE SHEATH DEFECTIVE 2 improves the efficiency of photosynthesis and growth in Arabidopsis, PLANT JOURNAL, 102(1), 129-137, 202004
  4. Dynamics of the leaf endoplasmic reticulum modulate beta-glucosidase-mediated stress-activated ABA production from its glucosyl ester, JOURNAL OF EXPERIMENTAL BOTANY, 71(6), 2058-2071, 20200325
  5. pCYOs: Binary vectors for simple visible selection of transformants using an albino-cotyledon mutant in Arabidopsis thaliana, PLANT BIOTECHNOLOGY, 36(1), 39-42, 201903
  6. A new carotenoid, 6-hydroxy-3-didehydrolutein, produced by recombinant Escherichia coli that expresses the violaxanthin biosynthesis and chaperone AtCYO1 genes—its structure and antioxidant activities., Phytochem. Lett., 35, 113-118, 2019
  7. Direct measurement of intercellular CO2 concentration in a gas-exchange system resolves overestimation using the standard method, JOURNAL OF EXPERIMENTAL BOTANY, 69(8), 1981-1991, 2018
  8. Overexpression of the protein disulfide isomerase AtCYO1 in chloroplasts slows dark-induced senescence in Arabidopsis, BMC PLANT BIOLOGY, 18, 2018
  9. Disruption of ureide degradation affects plant growth and development during and after transition from vegetative to reproductive stages, BMC Plant Biology, 18, 1-16, 2018
  10. Allantoin, a stress-related purine metabolite, can activate jasmonate signaling in a MYC2-regulated and abscisic acid-dependent manner, JOURNAL OF EXPERIMENTAL BOTANY, 67(8), 2519-2532, 2016
  11. Rice CYO1, an ortholog of Arabidopsis thaliana cotyledon chloroplastbiogenesis factor AtCYO1, is expressed in leaves and involved in photosynthetic performance, JOURNAL OF PLANT PHYSIOLOGY, 207, 78-83, 2016
  12. In vitro and in vivo evidence for oxalate oxidase activity of a germin-like protein from azalea, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 458(3), 536-542, 2015
  13. (6E) and (6Z)-9 '-Aporhodoxanthinone, novel carotenoids produced in zeaxanthin-synthesizing-Escherichia coli by redox stress, TETRAHEDRON LETTERS, 56(44), 6063-6065, 2015
  14. The purine metabolite allantoin enhances abiotic stress tolerance through synergistic activation of abscisic acid metabolism, PLANT CELL AND ENVIRONMENT, 37(4), 1022-1036, 2014
  15. Arabidopsis xanthine dehydrogenase mutants defective in purine degradation show a compromised protective response to drought and oxidative stress., Plant Biteochnology, 31, 173-178, 2014
  16. Arabidopsis cotyledon chloroplast biogenesis factor CYO1 uses glutathione as an electron donor and interacts with PSI (A1 and A2) and PSII (CP43 and CP47) subunits, JOURNAL OF PLANT PHYSIOLOGY, 169(12), 1212-1215, 2012
  17. RNA interference-mediated suppression of xanthine dehydrogenase reveals the role of purine metabolism in drought tolerance in Arabidopsis, FEBS LETTERS, 584(6), 1181-1186, 2010
  18. Chloroplast biogenesis during the early stage of leaf development in rice, PLANT BIOTECHNOLOGY, 27(1), 85-90, 2010
  19. Contribution of chloroplast biogenesis to carbon-nitrogen balance during early leaf development in rice, JOURNAL OF PLANT RESEARCH, 123(4), 617-622, 2010
  20. Normalization using ploidy and genomic DNA copy number allows absolute quantification of transcripts, proteins and metabolites in cells, PLANT METHODS, 6, 2010
  21. Arabidopsis cotyledon-specific chloroplast biogenesis factor CYO1 is a protein disulfide isomerase, Plant Cell, 19, 3157-3169, 2007
  22. Isolation of SIP, a protein that interacts with SPB, a possible transcriptional regulatory factor in Rhodobacter sphaeroides., Plant Cell Physiology, 48, 1504-1508, 2007
  23. Identification of a novel cis-element exhibiting cytokinin-dependent protein binding in vitro in the 5’-region of NADPH-protochlorophyllide oxidoreductase gene in cucumber., Plant Mol. Biol., 59, 631-645, 2005
  24. Inactivation and deficiency of core proteins of photosystems I and II caused by genetical phylloquinone and plastoquinone deficiency but retained lamellar structure in a T-DNA mutant of Arabidopsis., Plant J., 41, 627-637, 2005
  25. ARC3, a chloroplast division factor, is a chimera of prokaryotic FtsZ and part of eukaryotic phosphatigylinositol-4-phosphate 5-kinase., Plant Cell Physiology, 45, 960-967, 2004
  26. Distinctive features of plant organs characterized by global analysis of gene expression in Arabidopsis., DNA Res., 11, 11-25, 2004
  27. Digalactosyldiacylglycerol is a major glycolipid in floral organs of Petunia hybrida., Lipids, 38, 1107-1112, 2003
  28. Functional analysis of isoforms of NADPH:protochlorophyllide oxidoreductase (POR), PORB and PORC, in Arabidopsis thaliana., Plant Cell Physiology, 44, 963-974, 2003
  29. Light and cytokinin play a cooperative role in MGDG synthesis in greening cucumber cotyledons., Plant Cell Physiology, 44, 844-855, 2003
  30. Chlorophyllase as a serine hydrolase: Identification of a putative catalytic triad., Plant Cell Physiology, 44, 96-101, 2003
  31. Production of active bovine cathepsin C (dipeptidyl aminopeptidase I) in the methylotrophic yeast Candida boidinii., Appl. Micorobial. Biotech., 59, 252-258, 2002
  32. Identification of two differentially regulated isoforms of protochlorophyllide oxidoreductase (POR) from tobacco revealed a wide variety of light- and development-dependent regulations of POR gene expression among angiosperms., Photosynth. Res., 74, 165-172, 2002
  33. Two types of ferrochelatase in photosynthetic and non-photosynthetic tissues of cucumber; their difference in phylogeny, gene expression and localization., J. Biol. Chem., 277, 4731-4737, 2002
  34. Two distinct isopentenyl diphosphate isomerases in cytosol and plastid are differentially induced by environmental stresses in tobacco., FEBS Lett., 506, 61-64, 2001
  35. Two types of MGDG synthase genes, found widely in both "16:3" and "18:3" plants, differentially mediate galactolipid syntheses in photosynthetic and non-photosynthetic tissues in Arabidopsis thaliana., Proc. Natl. Acad. Sci. USA, 98, 10960-10965, 2001
  36. An Arabidopsis sigma factor (SIG2)-dependent expression of plastid-encoded tRNAs in chloroplasts., Plant Cell Physiology, 42, 1034-1043, 2001
  37. Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: Self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways., DNA Res., 8, 153-161, 2001
  38. Accumulation of plant galactolipid affects cell morphology of Escherichia coli., Biochem. Biophys. Res. Commun., 286, 114-118, 2001
  39. Isolation of protease component from maize cysteine protease-cystatin complex: Release of cystatin is not crucial for the activation of the cysteine protease., Plant Cell Physiology, 42, 710-716, 2001
  40. A Cysteine Protease from maize isolated in a complex with cystatin., Plant Cell Physiology, 42, 185-191, 2000
  41. Overexpression, enzymatic properties and localization of a ferrochelatase of cucumber., Plant Cell Physiology, 42, 192-199, 2000
  42. Chloroplast development in Arabidopsis thaliana requires the nuclear-encoded transcription factor sigma B., FEBS Lett., 485, 178-182, 2000
  43. NADPH-protochlorophyllide oxidoreductase in cucumber is encoded by a single gene and its expression is transcriptionally enhanced by illumination., Photosynth. Res, 64, 147-154, 2000
  44. Identification of a novel light-inducible isoform of NADPH-protochlorophyllide oxidoreductase from Arabidopsis thaliana., FEBS Lett., 474, 133-136, 2000
  45. A novel cysteine protease from maize isolated in a complex with cystatin., Plant Cell Physiology, 41, 185-191, 2000
  46. Photosynthetic regulatory gene cluster in an aerobic photosynthetic bacterium, Roseobacter denitrificans., J. Gen. Appl. Microbiol., 45, 129-134, 1999
  47. Magnesium insertion by magenesium chelatase in the biosynthesis of zinc-bacteriochlorophyll a in an aerobic acidophilic bacterium Acidiphilium rubrum., J. Biol. Chem., 274, 33594-33600, 1999
  48. Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate., Proc. Natl. Acad. Sci. USA, 96, 15362-15367, 1999
  49. Increased caroteniod production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway., Appl. Environ. Microb., 64, 2676-2680, 1998
  50. Production of the carotenoids lycopene, ß-carotene and astaxanthin in the food yeast Candida utilis., Appl. Environ. Microb., 64, 1226-1229, 1998
  51. Production of lycopene by the food yeast, Candida utilis that dose not Naturally synthesize carotenoid., Biochenol. Bioeng., 58, 306-308, 1998
  52. Enzymatic confirmation of reactions involved in routes to astaxanthin formation, elucidated using a direct substrate in vitro assay., Eur. J. Biochem., 252, 229-236, 1998
  53. Growth, pigmentation, and expression of the puf and puc operons in a light-responding-repressor (SPB)-disrupted Rhodobacter sphaeroides., Plant Cell Physiology, 39, 411-417, 1998
  54. Nucleotide sequence and transcriptional analysis of the flanking region of the gene(spb) for the trans-acting factor that controls light-mediated expression of the puf operon in Rhodobacter sphaeroides., Plant Cell Physiology, 38, 558-567, 1997
  55. Expression of the puf operon in an aerobic photosynthetic bacterium, Roseobacter denitrificans., Plant Cell Physiology, 37, 153-159, 1996
  56. A transcription factor with a leucine-zipper motif involved in light-dependent inhibition of expression of the puf operon in the photosynthetic bacterium Rhodobacter sphaeroides., Plant Cell Physiology, 37, 515-522, 1996
  57. A putative transcription factor binding to the upstream region of the puf operon in Rhodobacter sphaeroides., FEBS Lett., 382, 41-44, 1993
  58. Inhibition of accumulation of bacteriochlorophyll and carotenoids by blue light in aerobic photosynthetic bacterium, Roseobacter denitrificans, during anaerobic respiration., Plant Cell Physiology, 33, 1171-1174, 1992
  59. Blue-light irradiation reduces the expression of puf and puc operon of Rhodobacter sphaeroides under semi-aerobic conditions., Plant Cell Physilogy, 33, 471-475, 1992


  1. Patent, 6114580, 2017/03/24

External Funds

Acceptance Results of Competitive Funds

  1. Challenging Research (Pioneering), Research on development of plant growth promoters by chemical biology targeting photosynthesis, 2022
  2. Grant-in-Aid for Scientific Research (B), Redefining the physiological and ecological significance of the oxidative inactivation and degradation of the carbon dioxide fixing enzyme Rubisco., 2021
  3. Strategic Basic Research Programs(ALCA), 2015/11/01, 2020/03/31
  4. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2012/11/01, 2013/10/31
  5. KAKENHI, Analysis of the mechanism that prevents deactivation of Rubisco by oxygen oxidation, 2014, 2016
  6. KAKENHI, Analysis of the different chloroplast biogenesis in cotyledon and leaf, 2008, 2010
  7. KAKENHI, Analysis of chloroplast division mechanism by genome information, gene expression profile and reverse genetics., 2006, 2007
  8. KAKENHI, 2004, 2005
  9. KAKENHI, Mechanism of zinc-insertion into porphyrin ring in acidophilic photosynthetic bacteria, 2000, 2001
  10. KAKENHI, Regulation of expression of photosynthetic genes by the two-component regulatory system of photosynthetic bacteria, 1989, 1999
  11. Strategic Basic Research Programs(ALCA), 2015/11/01, 2019/03/31
  12. Strategic Basic Research Programs(ALCA), 2015/11/01, 2020/03/31