TAKAO MASAKI

Last Updated :2020/10/08

Affiliations, Positions
Hiroshima University Hospital, Professor
E-mail
masakithiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Kidney internal medicine

Affiliated Academic Societies

  • The Japanese Society of Internal Medicine Japanese Society of Nephrology The Japanese Society for Dialysis Therapy The Japanese Association of Rehabilitation Medicine Japanese Society for Peritoneal Dialysis Japanese Society for Hemodiafiltration American Society of Nephrology International Society of Nephrology European Renal Association

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Year, Clinical diagnosis and treatment I
  2. 2020, Undergraduate Education, Intensive, Practice for medical research
  3. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Nephrology
  4. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Nephrology
  5. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced research on Nephrology
  6. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Nephrology
  7. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Nephrology
  8. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Nephrology
  9. 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Nephrology
  10. 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Nephrology

Research Activities

Academic Papers

  1. Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice, DIABETOLOGY & METABOLIC SYNDROME, 11, 20190722
  2. Novel Asp511Thr mutation in McArdle disease with acute kidney injury caused by rhabdomyolysis, CEN CASE REPORTS, 8(3), 194-199, 201908
  3. Renal medullary tonicity regulates RNF183 expression in the collecting ducts via NFAT5, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 514(2), 436-442, 20190625
  4. microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress, PLOS ONE, 14(6), 20190614
  5. Long-term maintenance of hemoglobin levels in hemodialysis patients treated with bi-weekly epoetin beta pegol switched from darbepoetin alfa: a single-center, 12-month observational study in Japan, JOURNAL OF ARTIFICIAL ORGANS, 22(2), 146-153, 201906
  6. Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis, PLOS ONE, 12(3), 20170309
  7. Hypomagnesemia is not an independent risk factor for mortality in Japanese maintenance hemodialysis patients, INTERNATIONAL UROLOGY AND NEPHROLOGY, 51(6), 1043-1052, 201906
  8. Calnexin promotes the folding of mutant iduronate 2-sulfatase related to mucopolysaccharidosis type II, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 514(1), 217-223, 20190618
  9. Tocilizumab histologically improved AA renal amyloidosis in a patient with multicentric Castleman disease: A case report, CLINICAL NEPHROLOGY, 90(3), 232-236, 201809
  10. NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells, JOURNAL OF BIOLOGICAL CHEMISTRY, 294(1), 101-115, 20190104
  11. The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(12), 201812
  12. Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis, STEM CELLS TRANSLATIONAL MEDICINE, 7(12), 893-905, 201812
  13. pH after the first session of direct hemoperfusion with polymyxin B-immobilized fibers predicts mortality in patients with sepsis and septic shock, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(5), 1167-1173, OCT 2018
  14. TGF-beta 1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA, SCIENTIFIC REPORTS, 8, SEP 19 2018
  15. Coronary artery calcification score and common iliac artery calcification score in non-dialysis CKD patients, NEPHROLOGY, 23(9), 837-845, SEP 2018
  16. Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction, PLOS ONE, 13(8), AUG 16 2018
  17. Comparing the 12-month patency of low- versus high-pressure dilation in failing arteriovenous fistulae: A prospective multicenter trial (YOROI study), JOURNAL OF VASCULAR ACCESS, 19(5), 477-483, SEP 2018
  18. AA Amyloidosis and Atypical Familial Mediterranean Fever with Exon 2 and 3 Mutations., Case Rep Nephrol Dial, 7, 102-107, 2017
  19. Coronary artery calcification score and common iliac artery calcification score in non-dialysis CKD patients, Nephrology (Carlton), 23(9), 837-845, 2018
  20. A Case of Fibronectin Glomerulopathy Caused by Missense Mutations in the Fibronectin 1 Gene, kidney Int Rep, 2(5), 969-972, 2017
  21. Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II, CELL DEATH & DISEASE, 9(808), 20180724
  22. Klotho as a Therapeutic Target during the Development of Renal Fibrosis, SCIENTIFIC ASPECTS OF DIALYSIS THERAPY: JSDT/ISBP ANNIVERSARY EDITION, 189, 178-183, 2017
  23. Na+-Cl- cotransporter-mediated chloride uptake contributes to hypertension and renal damage in aldosterone-infused rats, AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 315(2), 300-312, 2018
  24. Dec1 and CLOCK Regulate Na+/K+-ATPase 1 Subunit Expression and Blood Pressure, HYPERTENSION, 72(3), 746-754, 201809
  25. Inhibition of the H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis, PLOS ONE, 13(5), 20180503
  26. A case of immunotactoid glomerulopathy with false-negative IgG staining, BMC NEPHROLOGY, 19, 20180615
  27. High-normal albuminuria and incident chronic kidney disease in a male nondiabetic population, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(4), 835-842, 201808
  28. N-terminal pro brain natriuretic peptide as a cardiac biomarker in Japanese hemodialysis patients, INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 41(3), 135-143, 201803
  29. Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report, BMC NEPHROLOGY, 19, 20180503
  30. Rationale and design of oBservational clinical Research In chronic kidney disease patients with renal anemia: renal proGnosis in patients with Hyporesponsive anemia To Erythropoiesis-stimulating agents, darbepoetiN alfa (BRIGHTEN Trial), CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(1), 78-84, 201802
  31. Addition of Novel Biomarkers for Predicting All-Cause and Cardiovascular Mortality in Prevalent Hemodialysis Patients, THERAPEUTIC APHERESIS AND DIALYSIS, 22(1), 31-39, 201802
  32. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-alpha and TGF-beta(1) pathways, SCIENTIFIC REPORTS, 7, 20170515
  33. Protective Effects of Japanese Soybean Paste (Miso) on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP), AMERICAN JOURNAL OF HYPERTENSION, 31(1), 43-47, 201801
  34. Diffuse large B-cell lymphoma presenting as bilateral renal infiltration leading to acute kidney injury, CEN CASE REPORTS, 6(2), 140-147, 201711
  35. Valproic acid attenuates renal fibrosis through the induction of autophagy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 21(5), 771-780, 201710
  36. Inhibition of H3K9 methyltransferase G9a ameliorates methylglyoxal-induced peritoneal fibrosis., Clin Exp Nephrol, 2017
  37. High glucose promotes TGF-beta 1 production by inducing FOS expression in human peritoneal mesothelial cells, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 20(1), 30-38, 2016
  38. Inhibition of H3K9 histone methyltransferase G9a attenuates renal fibrosis and retains klotho expression, KIDNEY INTERNATIONAL, 89(1), 147-157, 2016
  39. Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 27(1), 203-215, 2016
  40. Vascular access intervention by a nephrologist in Hiroshima, JOURNAL OF VASCULAR ACCESS, 16, S58-S61, 2015
  41. Expression of age-related factors during the development of renal damage in patients with IgA nephropathy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 19(5), 830-837, 2015
  42. Efficacy of add-on therapy of aliskiren to an angiotensin II receptor blocker on renal outcomes in advanced-stage chronic kidney disease: a prospective, randomized, open-label study, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 19(4), 631-638, 2015
  43. Hemodialysis Immediately After Cardiac Catheterization Is a Risk Factor for Intradialytic Hypotension, THERAPEUTIC APHERESIS AND DIALYSIS, 19(3), 245-249, 2015
  44. The Serum Lipids Levels may be Underestimated in Patients on Hemodialysis, INTERNAL MEDICINE, 54(8), 887-894, 2015
  45. Successful treatment with plasma exchange for ANCA-negative pauci-immune crescentic glomerulonephritis with D-negative hemolytic uremic syndrome, CLINICAL NEPHROLOGY, 82(4), 268-272, 2014
  46. Telomeric G-Tail Length and Hospitalization for Cardiovascular Events in Hemodialysis Patients, CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 9(12), 2117-2122, 2014
  47. Low serum testosterone is associated with atherosclerosis in postmenopausal women undergoing hemodialysis, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 18(3), 499-506, 2014
  48. Characteristic kidney pathology, gene abnormality and treatments in LCAT deficiency, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 18(2), 189-193, 2014
  49. Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats, PLOS ONE, 9(4), 2014
  50. Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta 1 signaling, KIDNEY INTERNATIONAL, 84(2), 297-307, 2013
  51. Morning blood pressure is useful for detection of left ventricular hypertrophy in hemodialysis patients, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 16(6), 921-929, 2012
  52. PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) HETERODIMERS REDUCE SERUM LDL-CHOLESTEROL (LDL-C) LEVELS IN MAINTENANCE HEMODIALYSIS (HD) PATIENTS ASSOCIATED WITH DYSLIPIDEMIA CHARACTERIZED BY INCREASED TRIGLYCERIDE-RICH LIPOPROTEINS, NEPHROLOGY DIALYSIS TRANSPLANTATION, 27, 215-216, 2012
  53. A SUPER HIGH-FLUX DIALYZER (PS: APS-EA) ELIMINATES 40% OF INJECTED RECOMBINANT HUMAN (RH) ERITHROPOIETIN (EPO) DURING 4-HOUR HEMODIALYSIS (HD), NEPHROLOGY DIALYSIS TRANSPLANTATION, 27, 213-213, 2012
  54. 15-Deoxy-Delta 12,14-prostaglandin J(2) Inhibits Angiotensin II-induced Fibronectin Expression via Hepatocyte Growth Factor Induction in Human Peritoneal Mesothelial Cells, THERAPEUTIC APHERESIS AND DIALYSIS, 14(1), 43-51, 2010
  55. C-C Chemokine Receptor 2 Expression by Circulating Monocytes Influences Atherosclerosis in Patients on Chronic Hemodialysis, THERAPEUTIC APHERESIS AND DIALYSIS, 13(3), 205-212, 2009
  56. Mizoribine Suppresses the Progression of Experimental Peritoneal Fibrosis in a Rat Model, NEPHRON EXPERIMENTAL NEPHROLOGY, 112(2), E59-E69, 2009
  57. PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta, LABORATORY INVESTIGATION, 89(1), 47-58, 2009
  58. Activation of signal transducer and activator of transcription 3 correlates with cell proliferation and renal injury in human glomerulonephritis, NEPHROLOGY DIALYSIS TRANSPLANTATION, 23(11), 3418-3426, 2008
  59. Calcium channel antagonists reduce restenosis after percutaneous transluminal angioplasty of an arteriovenous fistula in hemodialysis patients, THERAPEUTIC APHERESIS AND DIALYSIS, 12(3), 232-236, 2008
  60. Hypomagnesemia as a predictor of mortality in hemodialysis patients and the role of proton pump inhibitors: A cross-sectional, 1-year, retrospective cohort study., Hemodial Int, 20(4), 580-588, 2016.10
  61. Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice., PLoS One., 11(8), e0160993, 2016.8.11
  62. Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury, TRANSPLANTATION, 84(2), 207-213, 2007
  63. Signal transducer and activator of transcription 3 involvement in the development of renal interstitial fibrosis after unilateral ureteral obstruction, NEPHROLOGY, 12(6), 565-571, 2007
  64. Glucose-based PD solution, but not icodextrin-based PD solution, induces plasminogen activator inhibitor-1 and tissue-type plasminogen activator in human peritoneal mesothelial cells via ERK1/2, THERAPEUTIC APHERESIS AND DIALYSIS, 11(2), 94-100, 2007
  65. Effect of AST-120, an oral adsorbrnt, on inhibition of the loss of renal function in CRF patients, NEPHROLOGY DIALYSIS TRANSPLANTATION, 21, 383-383, 2006
  66. Mizoribine suppresses the progression of experimental peritoneal fibrosis in a rat model., Nephron Exp Nephrol, 112(2), 59-69, 2009
  67. Vascular access intervention by a nephrologist in Hiroshima, JOURNAL OF VASCULAR ACCESS, 16, S58-S61, 201511
  68. Expression of age-related factors during the development of renal damage in patients with IgA nephropathy, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 19(5), 830-837, 201510
  69. Hemodialysis Immediately After Cardiac Catheterization Is a Risk Factor for Intradialytic Hypotension, THERAPEUTIC APHERESIS AND DIALYSIS, 19(3), 245-249, 201506
  70. The Serum Lipids Levels may be Underestimated in Patients on Hemodialysis, INTERNAL MEDICINE, 54(8), 887-894, 2015
  71. Telomeric G-Tail Length and Hospitalization for Cardiovascular Events in Hemodialysis Patients, CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 9(12), 2117-2122, 201412
  72. Successful treatment with plasma exchange for ANCA-negative pauci-immune crescentic glomerulonephritis with D-negative hemolytic uremic syndrome, CLINICAL NEPHROLOGY, 82(4), 268-272, 201410
  73. 15-Deoxy-Delta 12,14-prostaglandin J(2) Inhibits Angiotensin II-induced Fibronectin Expression via Hepatocyte Growth Factor Induction in Human Peritoneal Mesothelial Cells, THERAPEUTIC APHERESIS AND DIALYSIS, 14(1), 43-51, 201002
  74. Mesenchymal stem cells ameliorate experimental peritoneal fibrosis by suppressing inflammation and inhibiting TGF-beta 1 signaling, KIDNEY INTERNATIONAL, 84(2), 297-307, 201308
  75. PDGF receptor tyrosine kinase inhibitor suppresses mesangial cell proliferation involving STAT3 activation., Clin Exp Immunol, 144(2), 353-361, 20060501
  76. ★, Tenascin expression may reflect the activity and chronicity of human IgA nephropathy., 50(4), 205-213, 19981001
  77. Role of tenascin in human immunoglobulin A nephropathy., 25(5), 247-254, 19970901
  78. The influence of steroid therapy in patients with IgA nephropathy., Nephron, 86(6), 197-198, 20001001
  79. Activation of the ERK pathway precedes tubular proliferation in the obstructed rat kidney., Kidney International, 63(4), 1256-1264, 20030401
  80. Heterogeneity of antigen expression explains controversy over glomerular macrophage accumulation in mouse glomerulonephritis., Nephrology Dialysis Transplantation, 18(1), 178-181, 20030101
  81. Activation of the extracellular-signal regulated protein kinase pathway in human glomerulopathies., Journal of the American Society of Nephrology, 15(7), 1835-1843, 20040601
  82. Low serum testosterone is associated with atherosclerosis in postmenopausal women undergoing hemodialysis., Clin Exp Nephrol, 20130701
  83. Morning blood pressure is useful for detection of left ventricular hypertrophy in hemodialysis patients, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 16(6), 921-929, 201212
  84. Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats, PLOS ONE, 9(4), 20140402
  85. Characteristic kidney pathology, gene abnormality and treatments in LCAT deficiency, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 18(2), 189-193, 201404
  86. Low serum testosterone is associated with atherosclerosis in postmenopausal women undergoing hemodialysis, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 18(3), 499-506, 201406
  87. Long-term maintenance of hemoglobin levels in hemodialysis patients treated with bi-weekly epoetin beta pegol switched from darbepoetin alfa: a single-center, 12-month observational study in Japan, JOURNAL OF ARTIFICIAL ORGANS, 22(2), 146-153, 2019
  88. Hypomagnesemia as a predictor of mortality in hemodialysis patients and the role of proton pump inhibitors: A cross-sectional, 1-year, retrospective cohort study, HEMODIALYSIS INTERNATIONAL, 20(4), 580-588, 2016
  89. Transition of adolescent and young adult patients with childhood-onset chronic kidney disease from pediatric to adult renal services: a nationwide survey in Japan, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 20(6), 918-925, 2016
  90. Seasonal variation in hemodialysis initiation: A single-center retrospective analysis, PLOS ONE, 12(6), 2017
  91. A Case of Fibronectin Glomerulopathy Caused by Missense Mutations in the Fibronectin 1 Gene, KIDNEY INTERNATIONAL REPORTS, 2(5), 969-972, 2017
  92. Protective Effects of Japanese Soybean Paste (Miso) on Stroke in Stroke-Prone Spontaneously Hypertensive Rats (SHRSP), AMERICAN JOURNAL OF HYPERTENSION, 31(1), 43-47, 2018
  93. Rationale and design of oBservational clinical Research In chronic kidney disease patients with renal anemia: renal proGnosis in patients with Hyporesponsive anemia To Erythropoiesis-stimulating agents, darbepoetiN alfa (BRIGHTEN Trial), CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(1), 78-84, 2018
  94. Rationale and design of oBservational clinical Research In chronic kidney disease patients with renal anemia: renal proGnosis in patients with Hyporesponsive anemia To Erythropoiesis-stimulating agents, darbepoetiN alfa (BRIGHTEN Trial) (vol 22, pg 78, 2018), CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(1), 85-86, 2018
  95. A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-alpha and TGF-beta(1) pathways, SCIENTIFIC REPORTS, 7, 2017
  96. Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report, BMC NEPHROLOGY, 19, 2018
  97. A case of immunotactoid glomerulopathy with false-negative IgG staining, BMC NEPHROLOGY, 19, 2018
  98. A consensus statement on health-care transition of patients with childhood-onset chronic kidney diseases: providing adequate medical care in adolescence and young adulthood, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(4), 743-751, 2018
  99. Tocilizumab histologically improved AA renal amyloidosis in a patient with multicentric Castleman disease: A case report, CLINICAL NEPHROLOGY, 90(3), 232-236, 2018
  100. Comparing the 12-month patency of low- versus high-pressure dilation in failing arteriovenous fistulae: A prospective multicenter trial (YOROI study), JOURNAL OF VASCULAR ACCESS, 19(5), 477-483, 2018
  101. pH after the first session of direct hemoperfusion with polymyxin B-immobilized fibers predicts mortality in patients with sepsis and septic shock, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(5), 1167-1173, 2018
  102. TGF-beta 1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA, SCIENTIFIC REPORTS, 8, 2018
  103. Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis, STEM CELLS TRANSLATIONAL MEDICINE, 7(12), 893-905, 2018
  104. The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(12), 2018
  105. Calnexin promotes the folding of mutant iduronate 2-sulfatase related to mucopolysaccharidosis type II, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 514(1), 217-223, 2019
  106. Hypomagnesemia is not an independent risk factor for mortality in Japanese maintenance hemodialysis patients, INTERNATIONAL UROLOGY AND NEPHROLOGY, 51(6), 1043-1052, 2019
  107. Renal medullary tonicity regulates RNF183 expression in the collecting ducts via NFAT5, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 514(2), 436-442, 2019
  108. microRNA-200c regulates KLOTHO expression in human kidney cells under oxidative stress, PLOS ONE, 14(6), 2019
  109. Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice, DIABETOLOGY & METABOLIC SYNDROME, 11, 2019
  110. High-normal albuminuria is associated with subclinical atherosclerosis in male population with estimated glomerular filtration rate >= 60 mL/min/1.73 m(2): A cross-sectional study, PLOS ONE, 14(8), 2019
  111. Relationship of matrix Gla protein and vitamin K with vascular calcification in hemodialysis patients, RENAL FAILURE, 41(1), 770-777, 2019
  112. Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16(INK4a), KIDNEY INTERNATIONAL, 96(5), 1162-1175, 2019
  113. Vascular access management after percutaneous transluminal angioplasty using a calcium alginate sheet: a randomized controlled trial, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34(9), 1592-1596, 2019
  114. Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(19), 2019
  115. ELEVATION OF SERUM BISPHENOL S (BPS) CONCENTRATIONS IN PATIENTS UNDERGOING HEMODIAYLSIS (HD) BY CHANGING DIALYZERS FROM POLYSULFONE TO POLYETHERSULFONE MEMBRANES, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34, 227-227, 2019
  116. THE IMPACT OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) ON SERUM LIPID PROFILE IN HEMODIALYSIS (HD) PATIENTS, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34, 293-293, 2019
  117. DOCOSAHEXAENOIC ACID ADMINISTRATION INCREASES EGFR THROUGH UPREGULATION OF NNOS EXPRESSION, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34, 2019
  118. LDL-CHOLESTEROL LEVEL IS ASSOCIATED WITH DOWNREGULATION OF KLOTHO EXPRESSION IN PATIENTS WITH IGA NEPHROPATHY, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34, 471-471, 2019
  119. WEEKLY AND MONTHLY ERYTHROPOIESIS STIMULATING AGENTS ARE REMOVED DURING HEMODIALYSIS SESSION, NEPHROLOGY DIALYSIS TRANSPLANTATION, 34, 521-521, 2019
  120. Iliopsoas Abscess in Hemodialysis Patients With End-Stage Kidney Disease, THERAPEUTIC APHERESIS AND DIALYSIS, 23(6), 534-541, 2019
  121. Relationship of serum magnesium level with body composition and survival in hemodialysis patients, HEMODIALYSIS INTERNATIONAL, 24(1), 99-107, 2020
  122. High-normal albuminuria is strongly associated with incident chronic kidney disease in a nondiabetic population with normal range of albuminuria and normal kidney function, CLINICAL AND EXPERIMENTAL NEPHROLOGY, 24(5), 435-443, 2020
  123. Hypoxia-preconditioned mesenchymal stem cells prevent renal fibrosis and inflammation in ischemia-reperfusion rats, STEM CELL RESEARCH & THERAPY, 11(1), 2020
  124. Eighteen-year follow-up cohort study on hepatitis B and C virus infections related long-term prognosis among hemodialysis patients in Hiroshima, JOURNAL OF MEDICAL VIROLOGY, 2020

Invited Lecture, Oral Presentation, Poster Presentation

  1. Inhibition of H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis, Ryo Tamura, Shigehiro Doi, Toshinori Ueno, Takao Masaki, ISN FRONTIERS MEETINGS 2018, 2018/02/22, Without Invitation, English
  2. TGF-b1 promotes fibrotic gene expression through induction of histone variant H3.3 and histone chaperone HIRA, Toshihiro Shindo, Shigehiro Doi, Kensuke Sasaki, Ayumu Nakashima, Takao Masaki, ISN FRONTIERS MEETINGS 2018, 2018/02/22, Without Invitation, English
  3. MicroRNA-200c is involved in Klotho reduction by oxidative stress in human tubular cells, Kenichi Morii, Satoshi Yamasaki, Shigehiro Doi, Kensuke Sasaki, Toshinori Ueno, Ayumu Nakashima, Takao Masaki, ISN FRONTIERS MEETINGS 2018, 2018/02/22, Without Invitation, English
  4. Prognostic Factors in sepsis patients who have undergone direct hemoperfusion with polymyxin b-immobilized fibers, Aiko Okubo, Ayumu Nakashima, Shigehiro Doi, Toshihiro Ueno, Takao Masaki, ISN FRONTIERS MEETINGS 2018, 2018/02/22, Without Invitation, English
  5. Mesenchymal stem cells cultured in serum-free medium ameliorate experimental renal fibrosis by their strong immunosuppressive effects, Ken Yoshida, Ayumu Nakashima, Shigehiro Doi, Toshinori Ueno, Yukio Kato, Yukihito Higashi, Takao Masaki, ISN FRONTIERS MEETINGS 2018, 2018/02/22, Without Invitation, English
  6. Inhibition of H3K4 methyltransferase SET7/9 ameliorates peritoneal fibrosis, Ryo Tamura, Shigehiro Doi, Toshinori Ueno, Takao Masaki, American Society of Nephrology 2017, 2017/10/31, Without Invitation, English
  7. TGF-b1 promotes fibrotic gene expression through induction of histone variant H3.3 and histone chaperone HIRA, Toshihiro Shindo, Shigehiro Doi, Kensuke Sasaki, Ayumu Nakashima, Takao Masaki, American Society of Nephrology 2017, 2017/10/31, Without Invitation, English
  8. MicroRNA-200c is involved in Klotho reduction by oxidative stress in human tubular cells, Kenichi Morii, Satoshi Yamasaki, Shigehiro Doi, Kensuke Sasaki, Toshinori Ueno, Ayumu Nakashima, Takao Masaki, American Society of Nephrology 2017, 2017/10/31, Without Invitation, Japanese
  9. Prognostic Factors in sepsis patients who have undergone direct hemoperfusion with polymyxin b-immobilized fibers, Aiko Okubo, Ayumu Nakashima, Shigehiro Doi, Toshihiro Ueno, Takao Masaki, American Society of Nephrology 2017, 2017/10/31, Without Invitation, English
  10. Mesenchymal stem cells cultured in serum-free medium ameliorate experimental renal fibrosis by their strong immunosuppressive effects, Ken Yoshida, Ayumu Nakashima, Shigehiro Doi, Toshinori Ueno, Yukio Kato, Yukihito Higashi, Takao Masaki, American Society of Nephrology 2017, 2017/10/31, Without Invitation, English
  11. Inhibitory Effect the Chromatin Histone H3-Lysine 4 Methyltransferase(SET7/9)on the Tubulointerstitial Fibrosis, Kensuke Sasaki, Ayumu Nakashima, Shigehiro Doi, Takao Masaki, American Society of Nephrology 2014, 2014/11/11, Without Invitation, English
  12. Mizoribine Suppressed Pyroptosis and Ameliorated Renal Inflammation in Aldosterone-Salt Treated Rats, Toshiki Doi, Shigehiro Doi, Ayumu Nakashima, Takao Masaki, American Society of Nephrology 2013, 2013/11/06, Without Invitation, English
  13. High Glucose Promotes TGF-β1 Productiono by Inducing FOS Expression in Human Peritoneal Mesothelial Cells, Shigehiro Doi, Keiko Kokoroishi, Ayumu Nakashima, Toshiki Doi, Takao Masaki, American Society of Nephrology 2013, 2013/11/06, Without Invitation, English
  14. Serum Lipids Levels may be Underestimated in Patients on Hemodialysis, Toshinori Ueno, Shigehiro Doi, Toru Kawai, Takao Masaki, WCN 2014 Satellite Symposium Kidney and Lipids, 2013/06/06, Without Invitation, English, fukuoka

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2014, 2016
  2. KAKENHI, 2013, 2015
  3. KANENHI, 2016, 2018
  4. KAKENHI, 2017, 2020
  5. KAKEN, 2016, 2018
  6. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  7. KAKENHI, 2019, 2022
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