Masaru Ueno

Last Updated :2019/05/07

Affiliations, Positions
Graduate School of Integrated Sciences for Life, ., Associate Professor
E-mail
scmuenohiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Ph.D., Kyoto Institute of Technology
  • Master of Engineering, Osaka Prefecture University

Research Fields

  • Biology;Basic biology;Genetics / Chromosome dynamics
  • Agricultural sciences;Boundary agriculture;Applied molecular and cellular biology

Research Keywords

  • Yeast
  • Chromosome
  • Telomere

Educational Activity

Course in Charge

  1. 2019, Liberal Arts Education Program1, 2Term, Introduction to Applied Chemistry, Chemical Engineering,and Biotechnology
  2. 2019, Undergraduate Education, First Semester, Training of Biotechnology I
  3. 2019, Undergraduate Education, 2Term, Molecular biology II
  4. 2019, Graduate Education (Master's Program) , First Semester, Seminar on Molecular Biotechnology
  5. 2019, Graduate Education (Master's Program) , Second Semester, Seminar on Molecular Biotechnology
  6. 2019, Graduate Education (Master's Program) , 1Term, Special Lectures in Integrated Sciences for Life
  7. 2019, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
  8. 2019, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
  9. 2019, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
  10. 2019, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
  11. 2019, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B
  12. 2019, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biotechnology
  13. 2019, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  14. 2019, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  15. 2019, Graduate Education (Master's Program) , 1Term, Advanced Technologies for Life Science
  16. 2019, Graduate Education (Master's Program) , 3Term, Introduction to Disease Models
  17. 2019, Graduate Education (Master's Program) , 1Term, Exercises in Biomedical Science A
  18. 2019, Graduate Education (Master's Program) , 2Term, Exercises in Biomedical Science A
  19. 2019, Graduate Education (Master's Program) , 3Term, Exercises in Biomedical Science B
  20. 2019, Graduate Education (Master's Program) , 4Term, Exercises in Biomedical Science B
  21. 2019, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biomedial Science
  22. 2019, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  23. 2019, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences

Award of Education

  1. 2011/.1
  2. 2016/12/27

Research Activities

Academic Papers

  1. Chromosome passenger complex is required for the survival of cells with ring chromosomes in fission yeast, PLOS ONE, 13(1), 20180103
  2. Mutation in fission yeast phosphatidylinositol 4-kinase Pik1 is synthetically lethal with defect in telomere protection protein Pot1, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 496(4), 1284-1290, 20180219
  3. Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells, SCIENTIFIC REPORTS, 8, 20181004
  4. Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine, PLOS ONE, 12(11), 20171109
  5. A diffusion model for the coordination of DNA replication in Schizosaccharomyces pombe, SCIENTIFIC REPORTS, 6, 20160105
  6. RSC Chromatin-Remodeling Complex Is Important for Mitochondrial Function in Saccharomyces cerevisiae, PLOS ONE, 10(6), 20150618
  7. The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 464(4), 1248-1253, 20150904
  8. Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 464(1), 140-146, 20150814
  9. The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts, YEAST, 32(9), 607-614, 201509
  10. Fission Yeast Exo1 and Rqh1-Dna2 Redundantly Contribute to Resection of Uncapped Telomeres, PLOS ONE, 10(10), 20151014
  11. Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, S. pombe, and Construction of an Overproduction System, PLOS ONE, 9(5), 20140314
  12. Rad51-Dependent Aberrant Chromosome Structures at Telomeres and Ribosomal DNA Activate the Spindle Assembly Checkpoint, MOLECULAR AND CELLULAR BIOLOGY, 34(8), 1389-1397, 201404
  13. SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(16), 5950-5955, 20140422
  14. 3,6-Epidioxy-1,10-bisaboladiene inhibits G(1)-specific transcription through Swi4/Swi6 and Mbp1/Swi6 via the Hog1 stress pathway in yeast, FEBS JOURNAL, 281(20), 4612-4621, 201410
  15. Fission Yeast RecQ Helicase Rqh1 Is Required for the Maintenance of Circular Chromosomes, MOLECULAR AND CELLULAR BIOLOGY, 33(6), 1175-1187, 201303
  16. A Double Mutant between Fission Yeast Telomerase and RecQ Helicase Is Sensitive to Thiabendazole, an Anti-Microtubule Drug, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 76(2), 264-269, 201202
  17. APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage, CELL DIVISION, 7, 20120209
  18. Fission yeast Pot1 and RecQ helicase are required for efficient chromosome segregation., Mol. Cell. Biol, 31, 495-506, 20110201
  19. Fission yeast Pot1 and RecQ helicase are required for efficient chromosome segregation., Mol. Cell. Biol., 31, 495-506, 20110501
  20. Fission Yeast Pot1 and RecQ Helicase Are Required for Efficient Chromosome Segregation, MOLECULAR AND CELLULAR BIOLOGY, 31(3), 495-506, 201102
  21. A novel method of screening cell-cycle blockers as candidates for anti-tumor reagents by using yeast as a screening tool, Biosci. Biotech. Biochem., 74(2), 411-414, 20100201
  22. Expression of mutant RPA in human cancer cells causes telomere shortening., Bioscience Biotechnology and Biochemistry, 74(2), 382-385, 20100201
  23. Roles of DNA Repair Proteins in Telomere Maintenance, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 74(1), 1-6, 201001
  24. Expression of Mutant RPA in Human Cancer Cells Causes Telomere Shortening, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 74(2), 382-385, 201002
  25. Rpd3/HDAC complex is present at the URS1 cis-element with hyperacetylated histone H3, Biosci. Biotechnol. Biochem, 73(2), 378-384, 20090201
  26. The Rpd3/HDAC Complex Is Present at the URS1 cis-Element with Hyperacetylated Histone H3, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 73(2), 378-384, 200902
  27. Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss., Molecular Biology of the Cell, 18(6), 2378-2387, 20070601
  28. The roles of DNA replication and rcombination factors in telomere maintenance, Seikagaku, 79(9), 868, 20070925
  29. Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss, MOLECULAR BIOLOGY OF THE CELL, 18(6), 2378-2387, 200706
  30. Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase, Genes to Cells, 11(12), 1367-1379, 20061201
  31. TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients, The EMBO Journal, 25(16), 3832-3842, 20060801
  32. A starvation-specific serine protease gene, isp6+, is involved in both autophagy and sexual development in Schizosaccharomyces pombe, Current Genetics, 49(6), 403-413, 20060321
  33. Dual DNA recognition codes of a short peptide derived from the basic leucine zipper protein EmBP1, Bioorganic & Medicinal Chemistry, 13(9), 3107-3116, 20050501
  34. Fission yeast Dna2 is required for generation of the telomeric single-strand overhang., Molecular and Cellular Biology, 24(21), 9557-9567, 20041101
  35. Sequence-Specific Binding of the Schizosaccharomyces pombe His1 Protein to Fission Yeast Telomeric DNA, Chemistry & Biodiversity, 1(9), 1344-1353, 20040923
  36. Fission yeast Arp6 is required for telomere silencing, but functions independently of Swi6, Nucleic Acids Research, 32(2), 736-741, 20040201
  37. Synthesis and crystal structures of metal complexes with 4,5-imidazole-dicarboxylate chelates: self-assembled structures via NHOC intermolecular hydrogen bonds, Inorganic Chemistry Communications, 7(11), 1191-1194, 20041101

Invited Lecture, Oral Presentation, Poster Presentation

  1. Fission yeast exo1 and rqh1 contribute to degradation of uncapped telomere, Masaru Ueno, The 8th international fission yeast meeting, 2015/06, Without Invitation, Kobe Japan
  2. Fission yeast exo1 and rqh1 contribute to degradation of uncapped telomere, Masaru Ueno, EMBO Conference on DNA Replication, Chromosome Segregation and Cell Division, 2015/07, Without Invitation, EMBO, Egham UK
  3. Identification of genes required for the formation or maintenance of circular chromosomes, Masaru Ueno, 2015/12, Without Invitation, Kobe Japan
  4. Screening of novel factors involved in formation and maintenance of circular chromosome in S. pombe, Masaru Ueno, The 4th International Symposium of the Mathematics on Chromatin Live Dynamics, 2015/12, Without Invitation
  5. Searching for cancer’s new weak points using fission yeast, 2015/11, With Invitation
  6. Understanding the workings of the Schizosaccharomyces pombe genome in three dimensions, Justin O'Sullivan, The Collaborated Seminar by 5 Graduated Schools, 2015/06, With Invitation, Masaru Ueno, Higashi-Hiroshima
  7. The Smc5/6 complex, regulation of recombination and replication fork stability, Jo Murray, HiHA国際シンポジウム, 2016/03, With Invitation, Higashi-hiroshima
  8. Analysis of glucose-dependent chromosome dynamics in fission yeast, Masaru Ueno, 2016/11/13, Without Invitation
  9. Using single particle trajectory statistics and polymer simulations to analyze and predict changes in chromatin structure, Andrew Seeber, 2016/11/28, With Invitation
  10. Analysis of glucose-dependent chromosome dynamics in fission yeast, Masaru Ueno, 2016/11/30, With Invitation
  11. The Smc5/6 complex and replication stress, Jo Murray, 4th HiHA International Symposium, 2017/03/10, With Invitation
  12. DNA repair pathway choice regulation by the small protein CYREN, Jan Karlseder, HiHA 4th International Symposium, 2017/03/10, With Invitation
  13. modeling chromatin dynamics as a polymer fiber:what we learn from single molecule tracking, Susan Gasser, 5th International Symposium of the Mathematics on Chromatin Live Dynamics in March, 2017/03/09, With Invitation
  14. lattice light sheet microscopy: development and applications, Bi-Chang Chen, 5th International Symposium of the Mathematics on Chromatin Live Dynamics, 2017/03/09, With Invitation
  15. Different regulation of centromere and telomere movement by glucose, medium and DNA damage in fission yeast, Masaru Ueno, 5th International Symposium of the Mathematics on Chromatin Live Dynamics, 2017/03/09, Without Invitation
  16. Different regulation of centromere and subtelomere movement by glucose, medium and DNA damage in fission yeast, Masaru Ueno, 4D Nucleome: The Cell Nucleus in Space and Time, 2017/05/15, Without Invitation, Krakow Poland
  17. Identification of factors affecting chromatin dynamics by live cell imaging and quantitative analysis in fission yeast, Masaru Ueno, 2018/03/21, Without Invitation
  18. Different regulation of centromere and subtelomere movement by glucose, medium and DNA damage in fission yeast, Masaru Ueno, seminar at Friedrich Miescher Institute for Biomedical Research in Switzerland, 2017/05/18, With Invitation, Susan M. Gasser, Switzerland
  19. Replication stress and chromosome instability, Jo Murray, 5th HiHA International Symposium, 2018/03/12, Without Invitation

Social Activities

Organizing Academic Conferences, etc.

  1. 2006/01
  2. 2014/11
  3. 2014/09
  4. 2016/07, 2016/07