MASAAKI TAKEDA

Last Updated :2026/02/03

Affiliations, Positions
Hiroshima University Hospital, Associate Professor/Lecturer

Basic Information

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Neurosurgery

Affiliated Academic Societies

  • The Japan Neurosurgical Society, 1998/05
  • Japanese Society of Spinal Surgery
  • The Japan Stroke Society
  • Japanese society of skull base surgery
  • The Japan brain dock society
  • Japanese society of clinical neurophysiology
  • Congress of Neurological Surgeons

Educational Activity

Course in Charge

  1. 2025, Undergraduate Education, Year, Medical Neuroscience III

Research Activities

Academic Papers

  1. Repeated human cranial bone-derived mesenchymal stem cell transplantation improved electrophysiological recovery in a spinal cord injury rat model, NEUROSCIENCE LETTERS, 844, 20250101
  2. Impact of intravenously administered cranial bone-derived mesenchymal stem cells on functional recovery in experimental spinal cord injury, NEUROSCIENCE LETTERS, 799, 20230316
  3. Establishment of longitudinal transcranial stimulation motor evoked potentials monitoring of the forelimbs and hindlimbs in an ischemic stroke rat model, SCIENTIFIC REPORTS, 12(1), 20221128
  4. Longitudinal electrophysiological changes after mesenchymal stem cell transplantation in a spinal cord injury rat model, PLOS ONE, 17(8), 20220805
  5. Healing process of Type II odontoid fractures after C1-C2 posterior screw fixation: Predictive factors for pseudoarthrosis, Surg Neurol Int., 116-116, 20220331
  6. Imaging evolution from "presyrinx" to syrinx in patient with spinal lipoma, Surg Neurol Int., 633-633, 20211230
  7. Transplantation of rat cranial bone-derived mesenchymal stem cells promotes functional recovery in rats with spinal cord injury, SCIENTIFIC REPORTS, 11(1), 20211109
  8. A novel bone-thinning technique for transcranial stimulation motor-evoked potentials in rats, SCIENTIFIC REPORTS, 11(1), 20210614
  9. Spinal Osseous Epidural Arteriovenous Fistula with Intradural Reflux: A Case Report, NMC Case Rep J, 8(1), 229-233, 20210611
  10. Spinal arteriovenous fistula in the lipoma of the filum terminale: A report of two cases and literature review, Surg Neurol Int, 103-103, 20210317
  11. Early Transplantation of Human Cranial Bone-derived Mesenchymal Stem Cells Enhances Functional Recovery in Ischemic Stroke Model Rats, Neurol Med Chir (Tokyo), 60(2), 83-93, 20200215
  12. Asymptomatic spinal dural arteriovenous fistula: case series and systematic review, J Neurosurg Spine, 31(5), 733-741, 20190719
  13. Concurrent Schwannoma and Meningioma Arising in the Same Spinal Level: A Report of Two Cases, NMC Case Rep J, 5(4), 105-109, 20180913
  14. Rat Cranial Bone-Derived Mesenchymal Stem Cell Transplantation Promotes Functional Recovery in Ischemic Stroke Model Rats, Stem Cells Dev, 27(15), 1053-1061, 20180801
  15. Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma, Neurol Med Chir (Tokyo), 57(10), 521-533, 20171015
  16. The characteristics of human cranial bone marrow mesenchymal stem cells, NEUROSCIENCE LETTERS, 606, 161-166, 20151008
  17. Gowers' intrasyringeal hemorrhage associated with Chiari type I malformation in Noonan syndrome., Surg Neurol Int, 5, 20140120
  18. Interactive effects of cell therapy and rehabilitation realize the full potential of neurogenesis in brain injury model, NEUROSCIENCE LETTERS, 555, 73-78, 20131025
  19. Interactive effects of cell therapy and rehabilitation realize the full potential of neurogenesis in brain injury model., Neurosci Lett, 555, 73-78, 20131025
  20. Simulated microgravity facilitates cell migration and neuroprotection after bone marrow stromal cell transplantation in spinal cord injury, STEM CELL RESEARCH & THERAPY, 4, 20130401
  21. Electrical stimulation enhances neurogenin2 expression through beta-catenin signaling pathway of mouse bone marrow stromal cells and intensifies the effect of cell transplantation on brain injury, NEUROSCIENCE LETTERS, 533, 71-76, 20130115
  22. Effects of simulated microgravity on proliferation and chemosensitivity in malignant glioma cells, Neurosci Lett, 463(1), 54-59, 20090929
  23. Posterolateral protrusion of the vertebral artery over the posterior arch of the atlas: quantitative anatomical study using three-dimensional computed tomography angiography., J Neurosurg Spine, 9(2), 167-174, 20080809
  24. Intravenous administration of bone marrow stromal cells increases survivin and Bcl-2 protein expression and improves sensorimotor function following ischemia in rats., Neurosci Lett, 430(2), 109-114, 20080110
  25. Human cranial bone-derived mesenchymal stem cells cultured under simulated microgravity can improve cerebral infarction in rats, EXPERIMENTAL NEUROLOGY, 382, 202412
  26. Relevance of the Foramen of Vesalius for Preoperative Tumor Embolization in Skull Base Meningioma, WORLD NEUROSURGERY, 187, E501-E508, 202407
  27. A novel rat model for longitudinal electrophysiological evaluation after cold-induced brain injury, JOURNAL OF NEUROSURGERY, 139(3), 840-847, 202309
  28. Assessment of Intraoperative Spinal Angiography via the Popliteal Artery for Spinal Vascular Diseases, WORLD NEUROSURGERY, 169, 1-8, 202301
  29. Effects of Preservation of the Semispinalis Cervicis Inserted into C2 on Craniocervical Alignment After Laminoplasty, World Neurosurg, e1367-e1376, 202102
  30. Effects of Preservation of the Semispinalis Cervicis Inserted into C2 on Craniocervical Alignment After Laminoplasty, WORLD NEUROSURGERY, 146, E1367-E1376, 202102
  31. Early Transplantation of Human Cranial Bone-derived Mesenchymal Stem Cells Enhances Functional Recovery in Ischemic Stroke Model Rats, NEUROLOGIA MEDICO-CHIRURGICA, 60(2), 83-93, 202002
  32. Localized controlled fibrin glue application with gelatin sponge for hemostasis and dural defect repair: Technical note, INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT, 18, 201912
  33. Cauda Equina Occupation Ratio as a New Imaging Parameter for the Evaluation of Spinal Dural Arteriovenous Fistulae, World Neurosurg, e1020-e1027, 201910
  34. Factors Related to Frailty Associated with Clinical Deterioration After Meningioma Surgery in the Elderly, World Neurosurg, e167-e173, 201811
  35. Factors Related to Frailty Associated with Clinical Deterioration After Meningioma Surgery in the Elderly, WORLD NEUROSURGERY, 119, E167-E173, 201811
  36. Usefulness of Preoperative Simulation in Skull Base Approach: A Case Report, J Neurol Surg B Skull Base, 79(suppl 4), s378-s382, 201810
  37. Isolated Tuberculoma Mimicking Foramen Magnum Meningioma in the Absence of Primary Tuberculosis: A Case Report, NEUROSPINE, 15(3), 277-282, 201809
  38. Concurrent Schwannoma and Meningioma Arising in the Same Spinal Level: A Report of Two Cases., NMC Case Rep J, 5(4), 105-109, 201809
  39. Rat Cranial Bone-Derived Mesenchymal Stem Cell Transplantation Promotes Functional Recovery in Ischemic Stroke Model Rats, STEM CELLS AND DEVELOPMENT, 27(15), 1053-1061, 201808
  40. Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma, Neurosurg Focus, 44(4), E14-E14, 201804
  41. Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma, NEUROSURGICAL FOCUS, 44(4), 201804
  42. Epidemiology and Overview of the Clinical Spectrum of Degenerative Cervical Myelopathy, Neurosurg Clin N Am, 29(1), 1-12, 201801
  43. Intraoperative Neurophysiologic Monitoring for Degenerative Cervical Myelopathy, Neurosurg Clin N Am, 29(1), 159-167, 201801
  44. Epidemiology and Overview of the Clinical Spectrum of Degenerative Cervical Myelopathy, NEUROSURGERY CLINICS OF NORTH AMERICA, 29(1), 1-+, 201801
  45. ★, Intraoperative Neurophysiologic Monitoring for Degenerative Cervical Myelopathy, NEUROSURGERY CLINICS OF NORTH AMERICA, 29(1), 159-+, 201801
  46. Pure Intra-optic Canal Schwannoma: Report of Two Cases, Asian J Neurosurg, 12(4), 797-800, 201710
  47. Review of Current Evidence Regarding Surgery in Elderly Patients with Meningioma, NEUROLOGIA MEDICO-CHIRURGICA, 57(10), 521-533, 201710
  48. The Position and Role of Four-Dimensional Computed Tomography Angiography in the Diagnosis and Treatment of Spinal Arteriovenous Fistulas, World Neurosurg, 611-619, 201707
  49. Neurologic Decline in an Older Patient with Repaired Myelomeningocele Complicated with Lumbar Canal Stenosis, World Neurosurg, 103(952), e1-e4, 201707
  50. The Position and Role of Four-Dimensional Computed Tomography Angiography in the Diagnosis and Treatment of Spinal Arteriovenous Fistulas, WORLD NEUROSURGERY, 103, 611-619, 201707
  51. Neurologic Decline in an Older Patient with Repaired Myelomeningocele Complicated with Lumbar Canal Stenosis, WORLD NEUROSURGERY, 103, 201707
  52. Preoperative simulation of the running course of the abducens nerve in a large petroclival meningioma: a case report and literature review, Neurosurg Rev, 40(2), 339-343, 201704
  53. Preoperative simulation of the running course of the abducens nerve in a large petroclival meningioma: a case report and literature review, NEUROSURGICAL REVIEW, 40(2), 339-343, 201704
  54. Surgical resection of large encephalocele: a report of two cases and consideration of resectability based on developmental morphology, Childs Nerv Syst, 33(3), 541-545, 201703
  55. Application of Compound Action Potential of Facial Muscles Evoked by Transcranial Stimulation as a Reference Waveform of Motor-evoked Potential in Spinal Surgery, Hiroshima J Med Sci, 66(1), 1-5, 201703
  56. A Case of Holocord Leptomeningeal Dissemination from Cerebellar Hemangioblastoma without von Hippel-Lindau Disease, Hiroshima J Med Sci, 66(1), 7-10, 201703
  57. Surgical resection of large encephalocele: a report of two cases and consideration of resectability based on developmental morphology, CHILDS NERVOUS SYSTEM, 33(3), 541-545, 201703
  58. Somatosensory evoked potentials in carotid artery stenting: Effectiveness in ascertaining cerebral ischemic events, J Clin Neurosci, 71-76, 201608
  59. Somatosensory evoked potentials in carotid artery stenting: Effectiveness in ascertaining cerebral ischemic events, JOURNAL OF CLINICAL NEUROSCIENCE, 30, 71-76, 201608
  60. A Case of Cutaneous Meningioma in the Rudimentary Meningocele, Hiroshima J Med Sci, 65(1), 9-12, 201603
  61. Ginkgo leaf sign: a highly predictive imaging feature of spinal meningioma, J Neurosurg Spine, 23(5), 642-646, 201511
  62. Ginkgo leaf sign: a highly predictive imaging feature of spinal meningioma, JOURNAL OF NEUROSURGERY-SPINE, 23(5), 642-646, 201511
  63. Visualization of regional cerebrospinal fluid flow with a dye injection technique in focal arachnoid pathologies, JOURNAL OF NEUROSURGERY-SPINE, 22(5), 554-557, 201505
  64. A case of petrous apex cholesterol granuloma successfully treated with endoscopic endonasal surgery, Hiroshima J Med Sci, 63(4), 39-42, 201412
  65. Application of 4D-CTA using 320-row area detector computed tomography on spinal arteriovenous fistulae: initial experience, NEUROSURGICAL REVIEW, 36(2), 289-296, 201304
  66. Utility of Direct Stimulation of Roots in Spinal Surgery, NEUROLOGIA MEDICO-CHIRURGICA, 51(5), 356-360, 201105
  67. Simultaneous cranial and spinal subdural hematoma., Neurol Med Chir (Tokyo), 45(12), 645-649, 200512
  68. [A case of aqueductal stenosis with acute progressive hydrocephalus during pregnancy], No Shinkei Geka, 33(1), 59-63, 200501
  69. Asymptomatic spinal dural arteriovenous fistula: case series and systematic review., J Neurosurg Spine, 19(5), 1-9, 2019
  70. Cauda Equina Occupation Ratio as a New Imaging Parameter for the Evaluation of Spinal Dural Arteriovenous Fistulae., World Neurosurg, 12(19), 31975-31978, 2019
  71. Asymptomatic spinal dural arteriovenous fistula: case series and systematic review, J Neurosurg Spine, 31, 733-741, 2019
  72. Cauda Equina Occupation Ratio as a New Imaging Parameter for the Evaluation of Spinal Dural Arteriovenous Fistulae., World Neurosurg, 130, e1020-e1027, 2019
  73. Application of Compound Action Potential of Facial Muscles Evoked by Transcranial Stimulation as a Reference Waveform of Motor-evoked Potential in Spinal Surgery., Hiroshima J Med Sci., 66(1), 1-5, 2017
  74. Thoracolumbar extradural arachnoid cyst--three surgical case reports, Neurol Med Chir (Tokyo), 53(2), 129-33, 2013
  75. Percutaneous endoscopic lumbar discectomy - early clinical experience, Neurol Med Chir (Tokyo), 52(9), 625-630, 2012
  76. Spontaneous C1 anterior arch fracture as a postoperative complication of foramen magnum decompression for Chiari malformation type 1, Surg Neurol Int, 138-138, 2011
  77. Simulated microgravity maintains the undifferentiated state and enhances the neural repair potential of bone marrow stromal cells., Stem Cells Dev., 20(5), 893-900, 2011
  78. Lateral buttock congenital dermal sinus tract., Neurol Med Chir (Tokyo), 51(6), 460-462, 2011
  79. Accuracy and pitfalls of multidetector-row computed tomography in detecting spinal dural arteriovenous fistulas., J Neurosurg Spine, 12(3), 243-248, 2010
  80. Spinal epidural granulocytic sarcoma in a child precedent to clinical manifestation of acute myeloid lymphoma: case report., Neurol Med Chir (Tokyo), 49(5), 221-224, 2009
  81. Multiple concurrent anastomotic procedures in the management of moyamoya disease: a case report with review of literature., Hiroshima J Med Sci, 57(1), 47-51, 2008
  82. Multi-detector-row CT angiography as a preoperative evaluation for spinal arteriovenous fistulae., Neurosurg Rev, 30(4), 321-326, 2007
  83. Penetrating injury of the upper cervical spine by a chopstick--case report., Neurol Med Chir (Tokyo), 47(7), 328-330, 2007
  84. Novel electrical stimulation sets the cultured myoblast contractile function to 'on'., Pathobiology, 73(6), 288-294, 2006

Invited Lecture, Oral Presentation, Poster Presentation

  1. Pitfalls in the evaluation of rat motor function using motor evoked potentials, 2025/10/30, Without Invitation, Japanese
  2. Characteristics of Pectoralis Minor Syndrome in Thoracic Outlet Syndrome, 2025/06/12, Without Invitation, Japanese
  3. Influence of physiologic closure of the metopic suture in Helmet Therapy for positional cranial deformity, 2025/06/05, Without Invitation, Japanese
  4. Intraoperative neurophysiological monitoring for congenital spinal anomalies of infant, 2024/11/07, Without Invitation, Japanese
  5. Evaluation of nerve conduction study of medial antebrachial cutaneous nerve in thoracic outlet syndrome, 2024/10/24, Without Invitation, Japanese
  6. Evaluation of nerve conduction study of medial antebrachial cutaneous nerve in thoracic outlet syndrome, 2024/10/16, Without Invitation, Japanese
  7. Evaluation of nerve conduction study of medial antebrachial cutaneous nerve in disputed thoracic outlet syndrome, Masaaki Takeda, Takafumi Mitsuhara, Yuyo Maeda, Nobutaka Horie, The 15th annual meeting of Asia Spine, 2024/07/06, Without Invitation, English, Taiwan Neurosurgical Spine Society, The Lin Hotel Taichung
  8. Results of treatment of severe carpal tunnel syndrome, 2024/06/13, Without Invitation, Japanese
  9. Diagnosis of pectoralis minor syndrome using various modalities, 2023/10/25, Without Invitation, Japanese
  10. The Spine painDETECT as a screening tool for peripheral nerve disease, 2023/06/15, Without Invitation, Japanese
  11. Case report: disappearing of SEP waveform during craniotomy for pediatric cerebellar tumor, 2022/07/07, Without Invitation, Japanese
  12. Diagnosis of nonspecific neurogenic thoracic outlet syndrome by F-wave, 2022/06/16, Without Invitation, Japanese
  13. Diagnosis of TOS by selective scalene and pectoralis minor muscle block, 2021/10/27, Without Invitation, Japanese
  14. Diagnosis of TOS by selective scalene and pectoralis minor muscle block, 2021/06/03, Without Invitation, Japanese
  15. Pectoralis minor syndrome in recurrent TOS, Masaaki Takeda,Takafumi Mitsuhara,Kiyoharu Shimizu,Kaoru Kurisu, 2020/11/09, Without Invitation, Japanese
  16. Pectoralis minor syndrome in recurrent TOS, 2020/10/15, Without Invitation, Japanese
  17. Intraoperative neurophysiological monitoring for the repair of neural tube defects, Masaaki Takeda, 2019/09/19, Without Invitation, English
  18. Differential diagnosis of neurogenic and vascular TOS with nerve conduction study, Masaaki Takeda, 2018/10/11, Without Invitation, Japanese
  19. Differential diagnosis of neurogenic and vascular TOS with nerve conduction study, Masaaki Takeda, 2018/06/15, Without Invitation, Japanese
  20. Spinal subdural hematoma secondary to cerebral subdural hematoma triggered by Japanese drum “wadaiko” performance, Masaaki Takeda, 9th Asia Spine, 2018/06/09, Without Invitation, English
  21. Diagnosis and postoperative evaluation of thoracic outlet syndrome by F-wave, Masaaki Takeda, 2017/10/13, Without Invitation, Japanese
  22. Diagnosis and postoperative evaluation of thoracic outlet syndrome by F-wave, Masaaki Takeda, 8th Asia Spine, 2017/06/09, Without Invitation, English
  23. Intraoperative neurophysiological monitoring during spine surgery, Masaaki Takeda, 1st-international-and-5th-annual-conference of Nepalese Society of Neurosurgeons, 2017/03/10, Without Invitation, English
  24. Somatosensory evoked potentials in carotid artery stenting: Effectiveness in ascertaining cerebral ischemic events, Masaaki Takeda, 2016/10/27, Without Invitation, Japanese
  25. Optimal stimulating point for lower extremities MEP in lumbar spine surgery., Masaaki Takeda, 2016/10/01, Without Invitation, Japanese
  26. Supraclavicular microsurgical approach for thoracic outlet syndrome, Masaaki Takeda, 2016/07/22, Without Invitation, Japanese
  27. Position-related changes of SEP in posterior approach to the cervical lesion, Masaaki Takeda, 2016/07/02, Without Invitation, Japanese
  28. Utility of nerve conduction study for thoracic outlet syndrome, Masaaki Takeda, Yamaguchi Satoshi, 2015/11/19, Without Invitation, Japanese
  29. Utility of nerve conduction study for thoracic outlet syndrome, Masaaki Takeda, Satoshi Yamaguchi, Kaoru Kurisu, 2015/11/05, Without Invitation, Japanese
  30. Diagnosis and surgical management of thoracic outlet syndrome, Masaaki Takeda, Satoshi Yamaguchi, Kaoru Kurisu, 2015/06/25, Without Invitation, Japanese
  31. The indirect stimulation technique used to assess pedicle screw placements, Masaaki Takeda, Satoshi Yamaguchi, Mizuki Morishige, Kaoru Kurisu, 2014/11/20, Without Invitation, Japanese
  32. The stimulation technique used to assess pedicle screw placements, Masaaki Takeda, Satoshi Yamaguchi, Kaoru Kurisu, 8th Asia Pacific Cervical Spine Society Meeting 2014, 2014/11/15, Without Invitation, English
  33. Indirect nerve root stimulation technique for asessment of instrument placements during spine surgery, Masaaki Takeda, Satoshi Yamaguchi, Mizuki Morishige, Kaoru Kurisu, 2014/10/11, Without Invitation, Japanese
  34. The stimulation technique used to assess pedicle screw placements, Masaaki Takeda, Satoshi Yamaguchi, 2014/09/12, Without Invitation, Japanese
  35. Accessory Nerve Schwannoma in Cisterna Magna; A Case Report, Masaaki Takeda, Satoshi Yamaguchi, Kaoru Kurisu, 2014/06/20, Without Invitation, Japanese
  36. Diagnosis and surgical management of bilateral thoracic outlet syndrome – a case report -, Masaaki Takeda, Satoshi Yamaguchi, Mizuki Morishige, Kaoru Kurisu, The 5th Annual Meeting of Asia Spine, 2014/06/14, Without Invitation, English, Masanori Ito Department of Neurosurgery, Juntendo University Urayasu Hospital, Station Conference Tokyo
  37. The stimulation technique used to assess pedicle screw placements, Masaaki Takeda, Satoshi Yamaguchi, Takafumi Mitsuhara, Mizuki Morishige, Kaoru Kurisu, 2014/06/13, Without Invitation, Japanese
  38. Intraoperative neurophysiological monitoring during spinal surgery, Masaaki Takeda, 2014/06/13, With Invitation, Japanese
  39. Transplantation of Bone Marrow Stromal Cells Cultured under Simulated Microgravity into a Spinal Cord Injury Rat, M. Takeda, T. Magaki, A. Sasaki, T. Manabe, M. Matsumoto, Y. Kawahara, L. Yuge, and K. Kurisu, 25th ASGSB Annual Meeting, 2009/11/05, Without Invitation, English
  40. Simulated Microgravity Inhibits Proliferation of Glioblastoma Cells, Takeda M, 24th Annual ASGSB Meeting, 2008/06/22, Without Invitation, English, Angers, France
  41. Simulated Microgravity Inhibits Proliferation of Malignant Glioma Cells, Takeda M, Okazaki T, Magaki T, Sasaki A,S L Wu,Kawahara Y, Yoshimoto R, Manabe T, Kajiume T, Yuge L and Kurisu K, the 23rd Annual Meeting of the ASGSB, 2007/10/25, Without Invitation, English, NASA Research Park, adjoining the Ames Research Center, Moffett Field,California
  42. Simulated Microgravity Inhibits Neural Differentiation of Mouse Bone Marrow Cells, Takeda T, Okazaki T, Magaki T, Yuge L. and Kurisu K, American Society for Gravitational and Space Biology 2006 Annual Meeting, 2006/11/05, Without Invitation, English, American Society for Gravitational and Space Biology, Sheraton National Hotel, Arlington
  43. Diagnosis of nonspecific neurogenic thoracic outlet syndrome by F-wave, Without Invitation, Japanese

Awards

  1. 2009, Travel Grant, American Society for Gravitational and Space Biology 25th Annual Meeting, Raleigh, NC, Transplantation of Bone Marrow Stromal Cells Cultured under Simulated Microgravity into a Spinal Cord Injury Rat

External Funds

Acceptance Results of Competitive Funds

  1. 2022, 2022
  2. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2022, 2024
  3. 2019, 2021
  4. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2019, 2021

Social Activities

Organizing Academic Conferences, etc.

  1. 2018/06, 2018/06