CHISA SHUKUNAMI

Last Updated :2019/04/09

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), ., Professor
Web Site
E-mail
shukunamhiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2013/07/23, Hiroshima University, Institute of Biomedical & Health Sciences, Professor
  • 2007/04/01, KyotoUniversity, Institute for Frontier Medical Sciences, Associate Professor
  • 1998/09/01, 2007/03/31, Kyoto University, Associate Professor

Educational Backgrounds

  • Osaka University, Graduate School, Division of Dental Research, Japan, 1991/04, 1995/03
  • Hiroshima University, Faculty of Dentistry, Japan, 1985/04, 1991/03

Academic Degrees

  • DDS Ph.D, Osaka University

Educational Activity

  • School of Dentistry:Program of Dentistry, Graduate School of Biomedical & Health Sciences:Medical and Dental Sciences Major, Graduate School of Biomedical & Health Sciences:Biomedical Sciences Major

In Charge of Primary Major Programs

  • Dentistry
  • Oral Health Science
  • Oral Engineering

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Functional basic dentistry
  • Biology;Biological Science;Functional biochemistry
  • Medicine,dentistry, and pharmacy;Clinical surgery;Orthopaedic surgery
  • Biology;Biological Science;Developmental biology

Research Keywords

  • tenomodulin
  • ligament
  • tendon

Affiliated Academic Societies

  • The Japanese Society for Bone and Mineral Reserach

Educational Activity

Course in Charge

  1. 2019, Undergraduate Education, 4Term, Advanced Coursework
  2. 2019, Undergraduate Education, 4Term, Overview of Dentistry
  3. 2019, Undergraduate Education, 1Term, Oral biochemistry
  4. 2019, Undergraduate Education, 3Term, Oral biochemistry
  5. 2019, Undergraduate Education, First Semester, Laboratory of Oral Function Sciences-Biochemistry,Physiology,Pharmacology-
  6. 2019, Undergraduate Education, 1Term, Topics in Denral Research
  7. 2019, Undergraduate Education, 2Term, Topics in Denral Research
  8. 2019, Undergraduate Education, 4Term, Start-Up Coursework
  9. 2019, Undergraduate Education, Intensive, Advanced Course of Mucosal Immunology on the bench
  10. 2019, Undergraduate Education, Intensive, Advanced Course of Mucosal Immunology on the bench
  11. 2019, Undergraduate Education, 1Term, International Future Dentistry with the Outcomes of Researches
  12. 2019, Undergraduate Education, Intensive, Practice of Molecular Biology and Biochemistry
  13. 2019, Undergraduate Education, Intensive, Advanced Course of Mucosal Immunology on the bench
  14. 2019, Undergraduate Education, 2Term, Practice on Basic Dental Sciences
  15. 2019, Undergraduate Education, 1Term, Basic Biochemistry
  16. 2019, Undergraduate Education, 4Term, Start-Up Coursework
  17. 2019, Undergraduate Education, 4Term, Advanced Coursework
  18. 2019, Undergraduate Education, 1Term, Basic Biochemistry
  19. 2019, Undergraduate Education, 4Term, Start-Up Coursework
  20. 2019, Undergraduate Education, 4Term, Advanced Coursework
  21. 2019, Graduate Education (Master's Program) , First Semester, Seminar on Dental and Medical Biochemistry
  22. 2019, Graduate Education (Master's Program) , Second Semester, Seminar on Dental and Medical Biochemistry
  23. 2019, Graduate Education (Master's Program) , First Semester, Research on Dental and Medical Biochemistry
  24. 2019, Graduate Education (Master's Program) , Second Semester, Research on Dental and Medical Biochemistry
  25. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced seminar on Dental and Medical Biochemistry
  26. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced seminar on Dental and Medical Biochemistry
  27. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced research on Dental and Medical Biochemistry
  28. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced research on Dental and Medical Biochemistry
  29. 2019, Graduate Education (Master's Program) , First Semester, Seminar
  30. 2019, Graduate Education (Master's Program) , Second Semester, Seminar
  31. 2019, Graduate Education (Master's Program) , First Semester, Research
  32. 2019, Graduate Education (Master's Program) , Second Semester, Research
  33. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar
  34. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar
  35. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced Research
  36. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced Research
  37. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Dental and Medical Biochemistry
  38. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Dental and Medical Biochemistry
  39. 2019, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Dental and Medical Biochemistry
  40. 2019, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Dental and Medical Biochemistry

Research Activities

Academic Papers

  1. Scleraxis and osterix antagonistically regulate tensile force-responsive remodeling of the periodontal ligament and alveolar bone, DEVELOPMENT, 142(4), 787-796, 20150215
  2. Loss of tenomodulin results in reduced self-renewal and augmented senescence of tendon stem/progenitor cells, Stem Cells and Development, 24(5), 597-609, 201501
  3. A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis, AMERICAN JOURNAL OF HUMAN GENETICS, 97(2), 337-342, 20150806
  4. Conservation of structure and function in vertebrate c-FLIP proteins despite rapid evolutionary change, Biochem Biophys Rep., 175-189, 2015
  5. FGF-2 stimulates the growth of tenogenic progenitor cells to facilitate the generation of Tenomodulin-positive tenocytes in a rat rotator cuff healing model, The American Journal of Sports Medicine, 2411-2422, 201510
  6. OASIS modulates hypoxia pathway activity to regulate bone angiogenesis, Scientific Reports, 5, 16455-Nov 12 2015, 2015
  7. Tenomodulin, 108-109, 2015
  8. Sox9- and Scleraxis-Cre Lineage Fate Mapping in Aortic and Mitral Valve Structures, Journal of Cardiovascular Development and Disease, 1(2), 163-176, 20140826
  9. The N- Terminal Cleavage of Chondromodulin-I in Growth- Plate Cartilage at the Hypertrophic and Calcified Zones during Bone Development, PLOS ONE, 9(4), 20140407
  10. Generation and characterization of ScxCre transgenic mice, GENESIS, 51(4), 275-283, 2013
  11. Tenomodulin expression in the periodontal ligament enhances cellular adhesion., PLoS One, 8, e60203, 2013
  12. Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis, NATURE GENETICS, 45(6), 676-679, 2013
  13. Pax1 acts as a negative regulator of chondrocyte maturation, EXPERIMENTAL CELL RESEARCH, 319(20), 3128-3139, 20131210
  14. Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament, DEVELOPMENT, 140(11), 2280-2288, 2013
  15. Direct conversion of tenocytes into chondrocytes by Sox9., Exp Cell Res, 318, 1492-1507, 2012
  16. Synthetic disulfide-bridged cyclic peptides mimic the anti-angiogenic actions of chondromodulin-I., Cancer Sci, 103, 1311-1318, 2012
  17. Conversion of human bone marrow-derived mesenchymal stem cells into tendon progenitor cells by ectopic expression of scleraxis., Stem Cells Dev, 21, 846-858, 2012
  18. Functional investigation of a non-coding variant associated with adolescent idiopathic scoliosis in zebrafish: elevated expression of the ladybird homeobox gene causes body axis deformation., PLOS Genetics, 12, 20160128
  19. Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor., J Cell Biol., 133, 457-468, 1996

Awards

  1. 1995年12月, The 3rd Pan Pacific Connective Tissue Societies Symposium Young Investigator Award

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2014, 2016

Social Activities

Organizing Academic Conferences, etc.

  1. 2017/09