Last Updated :2020/07/01

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Medicine), Associate Professor or Lecturer

Basic Information

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Psychiatric science

Research Keywords

  • depression
  • neuroimaging

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Intensive, Symptomatology, Diagnosis and Treatment
  2. 2020, Undergraduate Education, Intensive, Practice for medical research
  3. 2020, Undergraduate Education, 1Term, Psychiatry
  4. 2020, Undergraduate Education, 1Term, Psychiatry

Research Activities

Academic Papers

  1. Attenuated left prefrontal activation during a verbal fluency task in patients with depression., Neuropsychobiology, 47, 21-26, 20030401
  2. Brain activity during expectancy of emotional stimuli: an fMRI study., NeuroReport, 14, 51-55, 20030401
  3. Negative correlation between right prefrontal activity during response inhibition and impulsiveness: A fMRI study., European Archives of Psychiatry and Clinical Neuroscience, 254, 245-251, 20040401
  4. Prediction of immediate and future rewards differentially recruits cortico-basal ganglia loops., Nature Neuroscience, 7, 887-893, 20040401
  5. Brain mechanism of reward prediction under predictable and unpredictable environmental dynamics., Neural Networks in Healthcare: Potential and Challenges, 19, 1233-1241, 20060401
  6. Gender differences in brain activity toward unpleasant linguistic stimuli concerning interpersonal relationships: an fMRI study., European Archives of Psychiatry and Clinical Neuroscience, 255, 327-333, 20050401
  7. Reduced activation of posterior cingulate cortex during imagery in subjects with high degrees of alexithymia: a functional magnetic resonance imaging study., Biological Psychiatry, 57, 982-990, 20050401
  8. Attenuated anterior cingulate activation during a verbal fluency task in elderly patients with a history of multiple-episode depression., American Journal of Geriatric Psychiatry, 15(7), 594-603, 20070701
  9. Modulation of default-mode network activity by acute tryptophan depletion is associated with mood change: A resting state functional magnetic resonance imaging study, NEUROSCIENCE RESEARCH, 69(2), 129-134, FEB 2011
  10. Personality traits and the amplitude of spontaneous low-frequency oscillations during resting state, NEUROSCIENCE LETTERS, 492(2), 109-113, APR 1 2011
  11. Inter-individual discount factor differences in reward prediction are topographically associated with caudate activation, EXPERIMENTAL BRAIN RESEARCH, 212(4), 593-601, AUG 2011
  12. The Effect of Negative and Positive Emotionality on Associative Memory: An fMRI Study, PLOS ONE, 6(9), SEP 14 2011
  13. Neural and Personality Correlates of Individual Differences Related to the Effects of Acute Tryptophan Depletion on Future Reward Evaluation, NEUROPSYCHOBIOLOGY, 65(2), 55-64, 2012
  14. Sadness Enhances the Experience of Pain and Affects Pain-Evoked Cortical Activities: An MEG Study, JOURNAL OF PAIN, 13(7), 628-635, JUL 2012
  15. Effects of depression on reward-based decision making and variability of action in probabilistic learning, JOURNAL OF BEHAVIOR THERAPY AND EXPERIMENTAL PSYCHIATRY, 43(4), 1088-1094, DEC 2012
  17. Depressive symptoms and apathy are associated with psychomotor slowness and frontal activation, EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 262(6), 493-499, SEP 2012
  18. Cognitive behavioral therapy for depression changes medial prefrontal and ventral anterior cingulate cortex activity associated with self-referential processing, SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 9(4), 487-493, APR 2014
  19. Psychosocial functioning is correlated with activation in the anterior cingulate cortex and left lateral prefrontal cortex during a verbal fluency task in euthymic bipolar disorder: A preliminary fMRI study, PSYCHIATRY AND CLINICAL NEUROSCIENCES, 68(3), 188-196, MAR 2014
  20. Possible involvement of rumination in gray matter abnormalities in persistent symptoms of major depression: An exploratory magnetic resonance imaging voxel-based morphometry study, JOURNAL OF AFFECTIVE DISORDERS, 168, 229-235, OCT 15 2014
  21. Hippocampal activation during associative encoding of word pairs and its relation to symptomatic improvement in depression: A functional and volumetric MRI study, JOURNAL OF AFFECTIVE DISORDERS, 152, 462-467, JAN 2014
  22. fMRI Study of Social Anxiety during Social Ostracism with and without Emotional Support, PLOS ONE, 10(5), MAY 22 2015
  23. Direct and indirect influences of childhood abuse on depression symptoms in patients with major depressive disorder, BMC PSYCHIATRY, 15, OCT 14 2015
  24. Behavioral activation can normalize neural hypoactivation in subthreshold depression during a monetary incentive delay task, JOURNAL OF AFFECTIVE DISORDERS, 189, 254-262, JAN 1 2016
  25. Childhood poverty and recruitment of adult emotion regulatory neurocircuitry, SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 10(11), 1596-1606, NOV 2015
  26. Changes in the regional cerebral blood flow detected by arterial spin labeling after 6-week escitalopram treatment for major depressive disorder, JOURNAL OF AFFECTIVE DISORDERS, 194, 135-143, APR 2016
  27. Association of thalamic hyperactivity with treatment-resistant depression and poor response in early treatment for major depression: a resting-state fMRI study using fractional amplitude of low-frequency fluctuations, TRANSLATIONAL PSYCHIATRY, 6, MAR 8 2016
  28. Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices, JOURNAL OF AFFECTIVE DISORDERS, 208, 610-614, JAN 15 2017
  29. Increased amygdala reactivity following early life stress: a potential resilience enhancer role, BMC PSYCHIATRY, 17, JAN 18 2017
  30. Effects of behavioural activation on the neural basis of other perspective self-referential processing in subthreshold depression: a functional magnetic resonance imaging study, PSYCHOLOGICAL MEDICINE, 47(5), 877-888, APR 2017
  31. Disrupted Brain Activation and Deactivation Pattern during Semantic Verbal Fluency Task in Patients with Major Depression, NEUROPSYCHOBIOLOGY, 74(2), 69-77, 2016
  32. Neural circuitry of emotion regulation: Effects of appraisal, attention, and cortisol administration, COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE, 17(2), 437-451, APR 2017
  33. Regional brain functions in the resting state indicative of potential differences between depression and chronic pain, SCIENTIFIC REPORTS, 7, JUN 7 2017
  34. The neural correlates of the metacognitive function of other perspective: a multiple regression analysis study, NEUROREPORT, 28(11), 671-676, AUG 2 2017
  35. Prediction of clinical depression scores and detection of changes in whole-brain using resting-state functional MRI data with partial least squares regression, PLOS ONE, 12(7), JUL 12 2017
  36. Patients with major depressive disorder exhibit reduced reward size coding in the striatum, PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 79, 317-323, OCT 3 2017
  37. Multiple co-clustering based on nonparametric mixture models with heterogeneous marginal distributions, PLOS ONE, 12(10), OCT 19 2017
  38. BDNF as a possible modulator of EEG oscillatory response at the parietal cortex during visuo-tactile integration processes using a rubber hand, NEUROSCIENCE RESEARCH, 124, 16-24, NOV 2017
  39. Functional alterations of Postcentral gyrus Modulated by angry Facial expressions during intraoral Tactile stimuli in Patients with Burning Mouth syndrome: a Functional Magnetic resonance imaging study, FRONTIERS IN PSYCHIATRY, 8, NOV 6 2017
  40. Effects of behavioral activation on default mode network connectivity in subthreshold depression: A preliminary resting-state fMRI study, JOURNAL OF AFFECTIVE DISORDERS, 227, 156-163, FEB 2018
  41. Changes in resting-state brain networks after cognitive-behavioral therapy for chronic pain, PSYCHOLOGICAL MEDICINE, 48(7), 1148-1156, MAY 2018
  42. Effects of behavioural activation on the neural circuit related to intrinsic motivation, BJPSYCH OPEN, 4(5), 317-323, SEP 2018
  43. A prediction model of working memory across health and psychiatric disease using whole-brain functional connectivity, ELIFE, 7, 20181210
  44. Distinctive Neuroanatomical Substrates for Depression in Bipolar Disorder versus Major Depressive Disorder, CEREBRAL CORTEX, 29(1), 202-214, 201901
  45. Harmonization of resting-state functional MRI data across multiple imaging sites via the separation of site differences into sampling bias and measurement bias, PLOS BIOLOGY, 17(4), 201904
  46. Identification of depression subtypes and relevant brain regions using a data-driven approach, SCIENTIFIC REPORTS, 8, 20180920