TAKUYA KUMAMOTO

Last Updated :2024/04/03

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Pharmaceutical Sciences), Professor
E-mail
tkum632hiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 1996/04, 1997/03, Nagoya University, Department of Sciences, Postdoctoral fellow, Japan Society for the Promotion of Science
  • 1997/04, 2005/03, Chiba University, Research Associate
  • 2001/08, 2002/11, Universite catholique de Louvain, Department of Sciences, Postdoctoral fellow, Japan Society for the Promotion of Science
  • 2005/04, 2007/05, Chiba University, Lecturer
  • 2007/06, 2010/03, Chiba University, Associate Professor
  • 2010/04, 2017/03, Musashino University, Professor
  • 2017/04/01, Hiroshima University, Graduate School of Biomedical & Health Sciences, Professor

Academic Degrees

  • The University of Tokyo
  • The University of Tokyo

Research Fields

  • Medicine,dentistry, and pharmacy;Pharmacy;Chemical pharmacy

Research Keywords

  • Synthetic organic chemistry

Affiliated Academic Societies

  • Pharmaceutical Society of Japan
  • The Society of Synthetic Organic Chemistry, Japan
  • International Federation of Pharmacy
  • Chemical Society of Japan
  • The Japanese Association of Molecular Target Therapy of Cancer

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, First Semester, Outline of Pathology
  2. 2024, Undergraduate Education, 3Term, Introduction to Pharmaceutical Sciences
  3. 2024, Undergraduate Education, 1Term, Organic Chemistry IA
  4. 2024, Undergraduate Education, 2Term, Organic Chemistry IB
  5. 2024, Undergraduate Education, 3Term, Organic Chemistry IIA
  6. 2024, Undergraduate Education, 4Term, Organic Chemistry IIB
  7. 2024, Undergraduate Education, First Semester, Research Practice A
  8. 2024, Undergraduate Education, Second Semester, Research Practice B
  9. 2024, Undergraduate Education, First Semester, Practice of Organic Reactions
  10. 2024, Undergraduate Education, 1Term, Organic Chemistry III
  11. 2024, Undergraduate Education, 2Term, Medicinal Organic Chemistry
  12. 2024, Undergraduate Education, 3Term, Organic Chemistry IV
  13. 2024, Undergraduate Education, 3Term, Japanese Pharmacopoeia
  14. 2024, Undergraduate Education, Second Semester, Experiments in Organic Chemistry
  15. 2024, Undergraduate Education, Year, Special laboratory Works in Pharmaceutical Sciences I
  16. 2024, Undergraduate Education, Year, Special laboratory Works in Pharmaceutical Sciences II
  17. 2024, Undergraduate Education, Second Semester, Special laboratory Works in Pharmaceutical Sciences III
  18. 2024, Undergraduate Education, Year, Special laboratory Works in Clinical Pharmacy I
  19. 2024, Undergraduate Education, Year, Special laboratory Works in Clinical Pharmacy II
  20. 2024, Undergraduate Education, Year, Special laboratory Works in Clinical Pharmacy III
  21. 2024, Graduate Education (Master's Program) , First Semester, Lecture on Medicinal Science
  22. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Lecture on Medicinal Science
  23. 2024, Graduate Education (Master's Program) , First Semester, Lecture on Synthetic Organic Chemistry
  24. 2024, Graduate Education (Master's Program) , First Semester, Seminar on Synthetic Organic Chemistry
  25. 2024, Graduate Education (Master's Program) , Second Semester, Seminar on Synthetic Organic Chemistry
  26. 2024, Graduate Education (Master's Program) , First Semester, Research on Synthetic Organic Chemistry
  27. 2024, Graduate Education (Master's Program) , Second Semester, Research on Synthetic Organic Chemistry
  28. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Synthetic Organic Chemistry
  29. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Synthetic Organic Chemistry
  30. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Synthetic Organic Chemistry

Research Activities

Academic Papers

  1. Palladium-Catalyzed Reductive Heck Hydroarylation of Unactivated Alkenes Using Hydrosilane at Room Temperature, J Org Chem, 89(4), 2787-2793, 20240201
    Link to Paper Search Results by DOI
  2. Features and mechanisms of propofol-induced protein kinase C (PKC) translocation and activation in living cells, Front. Pharmacol., Sec. Neuropharmacology, 14, 1284586, 20231107
    Link to Paper Search Results by DOI
  3. Actinorhodin Biosynthesis Terminates with an Unprecedented Biaryl Coupling Reaction, Angew. Chem. Int. Ed, 62(5), e202214400, 20230126
    Link to Paper Search Results by DOI
  4. ★, Asymmetric Total Synthesis of Brasiliquinones B and C via Oxidative Cyclization of a Hydroquinone-Silyl Enol Ether Hybrid, Journal of Organic Chemistry, 87(18), 12491-12497, 20220830
    Link to Paper Search Results by DOI
  5. ★, Total Synthesis of 6-Deoxydihydrokalafungin, a Key Biosynthetic Precursor of Actinorhodin, and Its Epimer, Molecules, 26(21), 6397, 20211022
    Link to Paper Search Results by DOI
  6. ★, Total Synthesis of (+.-)-4-Deoxyblennolide C via Spirochromanone, Heterocycles, 103, 20210215
    Link to Paper Search Results by DOI
  7. Direct N1-Selective Alkylation of Hydantoins Using Potassium Bases, Chem Pharm Bull, 69(4), 407-410, 20210401
    Link to Paper Search Results by DOI
  8. ★, Chemistry of Anti-Hiv Active Trimeric Pyranonaphthoquinone Conocurvone: Synthetic Studies towards Monomeric Teretifolione B and Related Compounds, Heterocycles, Vol 100, No. 2, 2020, pp. 177 - 193(2), 177-193, 20191223
    Link to Paper Search Results by DOI
  9. Unveiling TwoConsecutive Hydroxylations:Mechanisms ofAromatic Hydroxylations Catalyzed by Flavin-DependentMonooxygenases for the Biosynthesis of Actinorhodin andRelated Antibiotics, ChemBioChem, 21(5), 623-627, 20190918
    Link to Paper Search Results by DOI
  10. Practical and Scalable Synthesis of a Glucokinase Activator via One-pot Difluorination and Julia Olefination, Org. Process Res. Dev., 24(7), 1294-1303, 20200616
    Link to Paper Search Results by DOI
  11. Possible utility of peptide-transporter-targeting [19F]dipeptides for visualization of the biodistribution of cancers by nuclear magnetic resonance imaging, International Journal of Pharmaceutics, 586, 119575, 20200702
    Link to Paper Search Results by DOI
  12. Design, synthesis, and evaluation of polyamine-memantine hybrids as NMDA channel blockers, Bioorganic & Medicinal Chemistry, 26(3), 603-608, 201802
    Link to Paper Search Results by DOI
  13. ★, Preparation of Optically Active 2,2-Disubstituted 5-Hydroxychromenes by the Enzymatic Resolution of Racemic Esters, Heterocycles, 97(1), 604-611, 20180518
    Repository URL
  14. ★, Asymmetric total syntheses of teretifolione B and methylteretifolione B via Diels-Alder reaction of optically active pyranobenzyne and substituted furans, TETRAHEDRON, 73(34), 5063-5071, 2017
    Link to Paper Search Results by DOI
  15. ★, Total synthesis of (+)-blennolide C and (+)-gonytolide C via spirochromanone, TETRAHEDRON LETTERS, 58(47), 4479-4482, 20171122
    Link to Paper Search Results by DOI
  16. Current Challenges and Potential Opportunities for the Pharmaceutical Sciences to Make Global Impact: An FIP Perspective, JOURNAL OF PHARMACEUTICAL SCIENCES, 105(9), 2489-2497, 2016
  17. An Insight into Different Stabilization Mechanisms of Phenytoin Derivatives Supersaturation by HPMC and PVP, JOURNAL OF PHARMACEUTICAL SCIENCES, 104(8), 2574-2582, 2015
  18. Synthesis and evaluation of C-11-labeled pyroglutamic acid amide derivatives for the imaging of glial cells by PET, JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 58, S45-S45, 2015
  19. ★, SELECTIVE SYNTHESIS OF BENZYL ENOL ETHERS OF beta-DICARBONYL COMPOUNDS IN BASIC CONDITION AND THE APPLICATION TOWARDS SYNTHESIS OF NAPHTHOQUINONES, HETEROCYCLES, 88(1), 817-825, 2014
  20. Catalytic Performance of Polystyrene-Bound ChibaG Derivatives as Guanidine Organobases in Asymmetric Michael Additions, HELVETICA CHIMICA ACTA, 97(3), 307-314, 2014
  21. ★, Synthesis of a Natural Chromenoquinone via the Diels-Alder Reaction of Pyranobenzyne and Furan, CHEMICAL & PHARMACEUTICAL BULLETIN, 62(8), 820-823, 2014
  22. Synthesis of ortho-Phenylenebis(guanidine) Derivatives with Potential Chirality, HELVETICA CHIMICA ACTA, 97(11), 1453-1468, 2014
  23. Quantitative analysis of miroestrol and kwakhurin for standardisation of Thai miracle herb "Kwao Keur' (Pueraria mirifica) and establishment of simple isolation procedure for highly estrogenic miroestrol and deoxymiroestrol, NATURAL PRODUCT RESEARCH, 27(4-5), 371-378, 2013
  24. Synthesis of the Aziridinomitosene Skeleton by Application of Guanidinium Ylide-Mediated Aziridination, HELVETICA CHIMICA ACTA, 96(3), 379-388, 2013
  25. Immobilized 1,2-Bis(guanidinoalkyl)benzenes: Potentially Useful for the Purification of Arsenic-Polluted Water, SYNLETT, 24(19), 2510-2514, 2013
  26. Synthesis of (-)-benzolactam-V8 by application of asymmetric aziridination, TETRAHEDRON, 68(3), 878-882, 2012
  27. Synthesis of jadomycin A and related jadomycin aglycons: structural re-examination of jadomycins S and T may be needed, TETRAHEDRON LETTERS, 53(4), 383-387, 2012
  28. CHIBA-G-CATALYZED INTRAMOLECULAR OXO-MICHAEL ADDITION: SYNTHETIC APPROACHES TO VITAMINE E SKELETON, HETEROCYCLES, 84(2), 1045-1056, 2012
  29. New 2-Aryl-1,4-naphthoquinone-1-oxime Methyl Ether Compound Induces Microtubule Depolymerization and Subsequent Apoptosis, JOURNAL OF PHARMACOLOGICAL SCIENCES, 118(4), 467-478, 2012
  30. Mechanism of nanoparticle formation from ternary coground phenytoin and its derivatives, JOURNAL OF PHARMACEUTICAL SCIENCES, 101(9), 3413-3424, 2012
  31. Enantioselective Construction of a Polyhydroxylated Pyrrolidine Skeleton from 3-Vinylaziridine-2-carboxylates: Synthesis of (+)-DMDP and a Potential Common Intermediate for (+)-Hyacinthacine A(1) and (+)-1-epi-Australine, JOURNAL OF ORGANIC CHEMISTRY, 77(18), 7988-7999, 2012
  32. Syntheses of Prekinamycin and a Tetracyclic Quinone from Common Synthetic Intermediates, HELVETICA CHIMICA ACTA, 94(4), 578-591, 2011
  33. Q172H Replacement Overcomes Effects on the Metabolism of Cyclophosphamide and Efavirenz Caused by CYP2B6 Variant with Arg262, DRUG METABOLISM AND DISPOSITION, 39(11), 2045-2048, 2011
  34. Biologically active constituents of Aglaia erythrosperma, NATURAL PRODUCT RESEARCH, 25(17), 1621-1628, 2011
  35. Synthesis of optically active left fragment of ambruticin via enzymatic resolution, JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 62(1), 114-114, 2010
  36. Complexability of o-bisguanidinobenzenes with arsenic and phosphoric acids in solution and solid states, and the potential use of their immobilized derivatives as solid base ligands for metal salts and arsenic acid, MOLECULAR DIVERSITY, 14(1), 131-145, 2010
  37. Synthetic studies on jadomycins: synthesis of dimethyljadomycin A, TETRAHEDRON LETTERS, 51(9), 1338-1340, 2010
  38. Ring-opening reaction of unactivated 3-arylaziridine-2-carboxylates with nitrile reagents, TETRAHEDRON, 66(21), 3836-3841, 2010
  39. Access to the nicotine system by application of a guanidine-catalyzed asymmetric Michael addition of diphenyliminoacetate with 3-pyridyl vinyl ketone, TETRAHEDRON LETTERS, 51(30), 3927-3930, 2010
  40. Design of New Scaffolds for Increased Superbasicity of Bisguanidine Proton Sponges, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 83(9), 1055-1057, 2010
  41. Synthetic Studies towards Kinamycin Antibiotics, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130(11), 1535-1541, 2010
  42. Synthesis, Physical Properties, and Cytotoxicity of Nitroxyl - Aziridine Hybrid, HELVETICA CHIMICA ACTA, 93(11), 2109-2114, 2010
  43. Exceptional Superbasicity of Bis(guanidine) Proton Sponges Imposed by the Bis(secododecahedrane) Molecular Scaffold: A Computational Study, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 6563-6572, 2010
  44. M10709, A NEW CYCLIC PEPTIDE ANTIBIOTIC FROM CLINICALLY ISOLATED STREPTOMYCES SP., HETEROCYCLES, 80(1), 281-288, 2010
  45. CHARACTERIZATION OF VARIOUS O-BISGUANIDINOBENZENE-BENZOIC ACID COMPLEXES IN SOLID AND IN SOLUTION STATES, HETEROCYCLES, 80(1), 303-311, 2010
  46. The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells, JOURNAL OF NATURAL MEDICINES, 63(1), 15-20, 2009
  47. Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7, JOURNAL OF NATURAL MEDICINES, 63(1), 21-27, 2009
  48. Inhibitory effect of the extracts from Thai medicinal plants on iNOS expression in mouse macrophage RAW 264.7, JOURNAL OF NATURAL MEDICINES, 63(1), 107-110, 2009
  49. Insight into estrogenicity of phytoestrogens using in silico simulation, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 379(1), 139-144, 2009
  50. Synthetic studies toward miroestrols: trials for elongation of the methyl group of 5-substituted 2-methyl-2-cyclohexanone to 3-methyl-2-butenyl function, TETRAHEDRON, 65(4), 771-785, 2009
  51. SEMI-QUANTITATIVE APPROACHES TO THE COORDINATION ABILITY OF o-BISGUANIDINOBENZENES WITH METAL SALTS, HETEROCYCLES, 77(1), 375-387, 2009
  52. DIHYDROXYLATION OF FUNCTIONALIZED COUMARIN DERIVATIVES, HETEROCYCLES, 77(1), 603-610, 2009
  53. ISOLATION OF beta-SITOSTEROL AND DIGALACTOPYRANOSYL-DIACYLGLYCERIDE FROM CITRUS HYSTRIX, A THAI TRADITIONAL HERB, AS PANCREATIC LIPASE INHIBITORS, HETEROCYCLES, 78(6), 1497-1505, 2009
  54. Isolation of Acridone Alkaloids and N-[(4-Monoterpenyloxy)phenylethyl]-Substituted Sulfur-Containing Propanamide Derivatives from Glycosmis parva and Their Anti-herpes Simplex Virus Activity, CHEMICAL & PHARMACEUTICAL BULLETIN, 57(11), 1246-1250, 2009
  55. Optical resolution of (+/-)-1,2-bis(2-methylphenyl)ethylene-1,2-diamine as a chiral framework for 2-iminoimidazolidine with 2-methylphenyl pendant and the guanidine-catalyzed asymmetric Michael reaction of tert-butyl diphenyliminoacetate and ethyl acrylate, JOURNAL OF ORGANIC CHEMISTRY, 73(1), 133-141, 2008
  56. A new sesquiterpene and other terpenoid constituents of Chisocheton penduliflorus, ARCHIVES OF PHARMACAL RESEARCH, 31(1), 21-27, 2008
  57. Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes, BIOCHEMICAL PHARMACOLOGY, 75(3), 752-760, 2008
  58. Electrochemical dissolution and redeposition of electropolymerized polyindole film, CHEMISTRY LETTERS, 37(2), 196-197, 2008
  59. The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2, CHEMICO-BIOLOGICAL INTERACTIONS, 172(1), 11-21, 2008
  60. Guanidine-catalyzed asymmetric synthesis of 2,2-disubstituted chromane skeletons by intramolecular oxa-Michael addition, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2759-2766, 2008
  61. Diels-Alder reactions using 4,7-dioxygenated indanones as dienophiles for regioselective construction of oxygenated 2,3-dihydrobenz[f]indenone skeleton, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 4, 2008
  62. Chemical constituents of Aristolochia constricta: Antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid, JOURNAL OF NATURAL PRODUCTS, 71(7), 1167-1172, 2008
  63. Simultaneous analysis of six phenethylamine-type designer drugs by TLC, LC-MS, and GC-MS, FORENSIC TOXICOLOGY, 26(1), 6-12, 2008
  64. EPIMERIZATION OF TRANS-3-ARYLAZIRIDINE-2-CARBOXYLATES AT THE C3 POSITION, HETEROCYCLES, 76(2), 1155-1170, 2008
  65. Ring-opening reactions of 3-aryl-1-benzylaziridine-2-carboxylates and application to the asymmetric synthesis of an amphetamine-type compound, HELVETICA CHIMICA ACTA, 90(1), 128-142, 2007
  66. Application of ascorbic acid 2-glucoside as a solubilizing agent for clarithromycin: Solubilization and nanoparticle formation, INTERNATIONAL JOURNAL OF PHARMACEUTICS, 331(1), 38-45, 2007
  67. Boron trichloride mediated regioselective claisen rearrangement of resorcinol derivatives: Application to resorcinol carvonyl ethers, SYNTHESIS-STUTTGART, 1785-1796, 2007
  68. Practical enzymatic desymmetrization of 2-(ethoxycarbonyl)propane-1,3-diyl dihexanoate and model cyclization for the A-D ring system of lysergic acid, HELVETICA CHIMICA ACTA, 90(7), 1420-1438, 2007
  69. ★, Total synthesis of (+/-)-methyl-kinamycin C, TETRAHEDRON, 63(24), 5189-5199, 2007
  70. Quantum-chemical study of 1,2-bis(dimethylethyleneguanidino)benzenes, HETEROCYCLES, 71(12), 2639-2658, 2007
  71. OXIDATIVE METABOLISM OF 5-MeO-DIPT BY RAT CYP2DENZYMES, DRUG METABOLISM REVIEWS, 39, 115-116, 2007
  72. Highly diastereoselective silyl-modified Sakurai multicomponent reaction, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45(20), 3357-3360, 2006
  73. Structural Revision of the Ring-Opened Product in the ZnCl 2-Catalyzed Reactions of 1-Benzyl-2-phenylaziridine with Thiols, Synlett, 362-364, 2004
    Link to Paper Search Results by DOI
  74. Synthetic studies on kinamycin antibiotics: Synthesis of a trioxygenated benz[f]indenone and its Diels-Alder reaction to a kinamycin skeleton, Helvetica Chimica Acta, 85, 1186-1195, 2002
    Link to Paper Search Results by DOI
  75. Remarkable Stereocontrol in the Palladium-Catalysed Cyclopropanation of Vinyl- and Dienylboronates by Substituted Diazoalkanes,, Advanced Synthesis and Catalysis, 344, 1063-1067, 2002
    Link to Paper Search Results by DOI
  76. Modified guanidines as chiral superbases: Application to asymmetric Michael reaction of glycine imine with acrylate or its related compounds, Chemical Communications, 245-246, 2001
    Link to Paper Search Results by DOI
  77. ★, Synthetic studies on kinamycin antibiotics: Elaboration of a highly oxygenated D ring, Tetrahedron, 57, 2717-2728, 2001
    Link to Paper Search Results by DOI
  78. Synthesis of enantiomeric 4-hydroxypropranolols from 1,4-dihydroxynaphthalene, Tetrahedron Asymmetry, 12, 791-795, 2001
    Link to Paper Search Results by DOI
  79. ★, Synthetic studies on kinamycin antibiotics: Elaboration of a highly oxygenated D-ring, Tetrahedron Letters, 41, 5693-5697, 2000
    Link to Paper Search Results by DOI
  80. Solvent effects on stereoselectivity in 2,3-dimethyl-4-chromanone cyclization by quinine-catalyzed asymmetric intramolecular oxo-Michael addition, Tetrahedron Asymmetry, 11, 4633-4637, 2000
    Link to Paper Search Results by DOI
  81. Enantioselective total synthesis of anti HIV-1 active (+)-calanolide A through a quinine-catalyzed asymmetric intramolecular oxo-Michael addition, Tetrahedron Letters, 41, 10229-10232, 2000
    Link to Paper Search Results by DOI
  82. An approach to anti-HIV-1 active Calophyllum coumarin synthesis: An enantioselective construction of 2,3-dimethyl-4-chromanone ring by quinineassisted intramolecular Michael-type addition, Tetrahedron Letters, 41, 3777-3780, 1999
    Link to Paper Search Results by DOI
  83. Enantioselective Horner-Wadsworth-Emmons reaction using chiral lithium 2-aminoalkoxides, Chemical and Pharmaceutical Bulletin, 45, 753-755, 1997
    Link to Paper Search Results by DOI
  84. Chiral lithium 2-aminoalkoxides as reagents for enantioselective Michael reaction, Tetrahedron Asymmetry, 5(8), 1431-1432, 1994
    Link to Paper Search Results by DOI

Publications such as books

  1. 2019/04, Chapter 1. Recent Progress in Aryne Cycloaddition Reactions, Cycloaddition Reactions: Advances in Research and Applications, NOVA SCIENCE PUBLISHERS, 2019, 4, Scholarly Book, Joint work, 英語, Takuya KUMAMOTO, Kazuaki KATAKAWA, 978-1-53615-420-7, 282, 45, Chapter 1.
    Amazon URL

Invited Lecture, Oral Presentation, Poster Presentation

  1. Modified synthesis of ß-amyloid PET tracer [18F]FC119S for our automated synthesizer, Takuya Kumamoto, Jun Ogura, Makoto Funasaka, Eiko N. Minakawa, Kazuhiko Seki, Koichi Kato, FIP Brisbane 2023 81TH FIP WORLD CONGRESS OF PHARMACY AND PHARMACEUTICAL SCIENCES, 2023/09/26, Without Invitation, English, FIP, Brisbane
  2. Total Synthesis of Brasiliquinones, Takuya KUMAMOTO, International Congress on Pure & Applied Chemistry (ICPAC) Bali 2023, 2023/09/14, With Invitation, English, INSTITUT KIMIA MALAYSIA, Bali (online)
    Related URL
  3. Synthetic Studies toward Natural Xanthone Blennolides via Spirochromanones, Takuya Kumamoto, ICPAC Kota Kinabalu 2022, 2022/11/27, With Invitation, English, Institut Kimia Malaysia, Kota Kinabalu, Malaysia
    Related URL, Attached File's URL
  4. Direct N1-selective alkylation of hydantoins using potassium bases, Takuya Kumamoto, Yumi Shintani, Koichi Kato, Masashi Kawami, Mikihisa Takano, FIP Seville 2022 80TH FIP WORLD CONGRESS OF PHARMACY AND PHARMACEUTICAL SCIENCES, 2022/09/20, Without Invitation, English
  5. Digital science, accelerating medicine discovery, Takuya Kumamoto, FIP Seville 2022 80TH FIP WORLD CONGRESS OF PHARMACY AND PHARMACEUTICAL SCIENCES, 2022/09/19, With Invitation, English, FIP (International Pharmacy Federation), Seville, Spain
    Related URL
  6. Synthetic study toward natural chromenoquinone teretifolione B via chiral chromene synthesis, Takuya Kumamoto, Mika Kainuma, Yuki Wakamiya, Kazuaki Katakawa, AIMECS 2021 13th AFMC International Medicinal Chemistry Symposium, 2021/11/29, Without Invitation, English, Asian Federation for Medicinal Chemistry (AFMC)
  7. Asymmetric synthesis of brasiliquinones, Takuya Kumamoto, Hiroki Miyake, Ryo Nakajima, 47th Progress of Reaction and Synthesis Symposium, 2021/10/02, Without Invitation, Japanese, Pharmaceutical Society of Japan
  8. Synthetic study towards anticancer aromatic polyketides antibiotics, Takuya Kumamoto, Hiroshima University and Council of Scientific & Industrial Research JOINT INTERNATIONAL WORKSHOP​, 2021/09/30, With Invitation, English, Hiroshima University and Council of Scientific & Industrial Research, Zoom
    Related URL
  9. Asymmetric total synthesis of brasiliquinones, Hiroki Miyake, Ryo Nakajima, Takuya Kumamoto, 37th Organic Synthesis Seminer, 2021/09/16, Without Invitation, Japanese, Online
  10. Synthetic study toward chromene / xanthone natural products, Takuya Kumamoto, Joint Symposium between CSIR-CDRI and HiU-P-DDS, 2021/03/05, With Invitation, English, Hiroshima University, CSIR-CDRI, (Zoom meeting)
  11. Synthetic study toward polyketide antibiotics, Takuya Kumamoto, HU and BITS Pilani 2nd Joint Workshop, 2020/11/20, With Invitation, English, Hiroshima University, BITS Pilani, (Zoom meeting)
  12. Total synthesis of (+-)-brasiliquinone, Hiroki Miyake, Ryo Nakajima, Takuya Kumamoto, 64th Pharmaceutical Society of Japan Kanto branch, 2020/09/19, Without Invitation, Japanese, Pharmaceutical Society of Japan Kanto branch, Tokyo (Online)
  13. Introduction of SIG New Medicines, Takuya Kumamoto, Intro to FIP SIG: Drug Delivery & Manufacturing, New Medicines & New Generation of Pharm. Scientists, 2020/07/12, With Invitation, English, FIP, Zoom meeting
  14. Total synthesis of 6-deoxydehydrokalafungin, 45th Symposium of Progress in Organic Reactions and Synthesis, 2019/10/28, Without Invitation, Japanese
  15. Synthesis of Polycyclic Chromene Natural Products Based on Benzyne Cycloaddition Strategy, Kazuaki Katakawa, Mika Kainuma, Shun Maeda, Saki Kato, Ryusei Fukagawa, Shunsuke Sueki, Masahiro Anada, Takuya Kumamoto, 27th International Society of Heterocyclic Chemistry Congress, 2019/09/03, Without Invitation, English
  16. Total synthesis of 6-deoxydehydrokarafungin, Takuya Kumamoto, Mika Kainuma, Azusa Takahashi, Yoshika Matsuo, Masahiro Anada, Kazuaki Katakawa, 27th International Society of Heterocyclic Chemistry Congress, 2019/09/03, Without Invitation, English, International Society of Heterocyclic Chemistry, Kyoto
    Related URL
  17. Synthetic studies towards natural xanthones blennolides via spiro intermediates, Tsubasa Nakaue, Takuya NISHIO, Ryo NAKAJIMA, Takuya KUMAMOTO*, 27th International Society of Heterocyclic Chemistry Congress, 2019/09/03, Without Invitation, English, Kyoto
  18. Synthetic Studies toward Natural Xanthones via Spiro Compounds, Takuya Kumamoto, Kanna Adachi, Sho Hasegawa, Takuya Nishio, Tsubasa Nakaue, Ryo Nakajima, and Kazuaki Katakawa, 27th French-Japanese Society of Medicinal and Fine Chemistry, 2019/05/20, Without Invitation, English
  19. Synthesis and evaluation of 11C-labeled pyrogluamic amide derivatives as pet tracers for glial cells, Takuya Kumamoto, Miho Shukuri, Naoki Ihara, Koichi Kato, Takashi Hanakawa, 78th FIP World Congress of Pharmacy and Pharmaceutical Sciences, 2018/09/03, Without Invitation, English, FIP, Glasgow, England
  20. Total synthesis of blennolide C and gonytolide C, Kumamoto, T., Adachi, K.; Hasegawa, S.; Katakawa, K.;, International Symposium on Main Group Chemistry Directed towards Organic Synthesis, 2018/08/25, Without Invitation, English
    Related URL
  21. Synthetic Studies of Eustifoline-B from Pyranobenzyne, Kazuaki Katakawa, Shun Maeda, Ryusei Fukagawa, Masahiro Anada, Takuya Kumamoto, Pharmaceutical Society of Japan 138th Annual Meeting, 2018/03/27, Without Invitation, Japanese
  22. Synthetic Studies toward DDHK as an biosynthetic intermediate of actinorhodin, Azusa Takahashi, Mika Kainuma, Kazuaki Katakawa, Masahiro Anada, Takuya Kumamoto, Pharmaceutical Society of Japan 138th Annual Meeting, 2018/03/26, Without Invitation, Japanese
  23. Synthetic Studies on Blennolides, Takuya Nishio, Ai Kotake, Sayaka, Yamaguchi, Asuna Okuda, Kazuaki Katakawa, Takuya Kumamoto, 2017/10/21, Without Invitation, Japanese
  24. Environmental impact of drug manufacturing, Takuya Kumamoto, FIP PSWC 2017, 2017/05/24, With Invitation, English, International Pharmacy Federation, Stockholm
    Related URL
  25. Synthetic studies toward natural chromenes with biological activity: Asymmetric total synthesis of gonytolide C and blennolide C via spiro chromanone, Kanna Adachi, Kazuaki Katakawa, Takuya Kumamoto, the 6th FIP Pharmaceutical Sciences World Congress 2017, 2017/05/21, Without Invitation, English, International Pharmaceutical Federation, Stockholm

Social Activities

History as Committee Members

  1. FIP Foundation, 2023/10/01, FIP
  2. International Pharmacy Federation, Board of Pharmaceutical Sciences, Special Interest Group New Medicines, Chair, 2019/09, 2023/09, International Pharmacy Federation
  3. International Affairs, 2016/04, 2021/03, Pharmaceutical Society of Japan
  4. Board of Pharmaceutical Sciences， Special Interest Group on Drug Design and Discovery, 2012/04, 2019/09, International Pharmacy Federation