AKINORI AWAZU

Last Updated :2026/07/06

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
E-mail
awahiroshima-u.ac.jp
Self-introduction
0

Basic Information

Major Professional Backgrounds

  • 2006/11/01, 2007/03/31, Hiroshima University, Graduate School of Science, Research Associate
  • 2007/04/01, 2011/09/30, Hiroshima University, Graduate School of Science, Assistant Professor
  • 2011/10/01, 2019/03/31, Hiroshima University, Graduate School of Science, Associate Professor

Educational Backgrounds

  • Osaka Prefecture University, Japan, 1999/04, 2001/03
  • Ibaraki University, Japan, 1997/04, 1999/03
  • Ibaraki University, Japan, 1993/04, 1997/03

Academic Degrees

  • Doctor of Engineering, Osaka Prefecture University
  • Master, Ibaraki University

Educational Activity

  • [Bachelor Degree Program] School of Science : Mathematics : Mathematics
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Mathematical and Life Sciences
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Mathematical and Life Sciences

Research Fields

  • Biological Sciences;Genome science;Genome biology
  • Biology;Basic biology;Genetics / Chromosome dynamics
  • Informatics;Frontiers of informatics;Life / Health / Medical informatics
  • Agricultural sciences;Animal life science;Veterinary medical science
  • Biology;Biological Science;Biophysics

Research Keywords

  • Theoretical Biology
  • Molecular cell biology
  • Basic medical science for cats and humans

Affiliated Academic Societies

  • Physical Society of Japan
  • Biophysical Society of Japan
  • Society of Plant Physiology of Japan

Educational Activity

Course in Charge

  1. 2026, Undergraduate Education, 1Term, Advanced Mathematics
  2. 2026, Undergraduate Education, 4Term, Mathematics for Computation
  3. 2026, Undergraduate Education, 3Term, elementary nonlinear studies
  4. 2026, Undergraduate Education, 2Term, Theory of Complex Systems
  5. 2026, Undergraduate Education, 4Term, Mathematics for Modeling and Simulation
  6. 2026, Undergraduate Education, First Semester, Special Study of Mathematics and Informatics for Graduation
  7. 2026, Undergraduate Education, Second Semester, Special Study of Mathematics and Informatics for Graduation
  8. 2026, Undergraduate Education, First Semester, Special Lectures in Mathematics(Bioinformatics in Veterinary Medicine)
  9. 2026, Graduate Education (Master's Program) , 1Term, Special Lectures in Integrated Sciences for Life
  10. 2026, Graduate Education (Master's Program) , 1Term, Introduction to Applied Mathematics and Computational Science
  11. 2026, Graduate Education (Master's Program) , Year, Research for Academic Degree Dissertation in Mathematical and Life Sciences
  12. 2026, Graduate Education (Master's Program) , 4Term, Mathematical Modeling D
  13. 2026, Graduate Education (Master's Program) , 4Term, Computational Mathematics B
  14. 2026, Graduate Education (Master's Program) , 2Term, High-Performance Computing and Data Science
  15. 2026, Graduate Education (Master's Program) , First Semester, Special Lecture on MathematicDNAal and Life Sciences C
  16. 2026, Graduate Education (Master's Program) , 2Term, Topical Seminar in Mathematical Science C
  17. 2026, Graduate Education (Master's Program) , 4Term, Topical Seminar in Mathematical Science D
  18. 2026, Graduate Education (Master's Program) , First Semester, Exercises in Applied Mathematics and Computational Science A
  19. 2026, Graduate Education (Master's Program) , Second Semester, Exercises in Applied Mathematics and Computational Science B
  20. 2026, Graduate Education (Doctoral Program) , Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  21. 2026, Graduate Education (Doctoral Program) , First Semester, Special Lecture on Mathematical and Life Sciences G

Research Activities

Academic Papers

  1. ★, Whole-genome sequencing of CRFK and PG-4 cells to infer the phenotype of the original donor cats, Companion Animal Health and Genetics, 13, 1-15, 2026
    Link to Paper Search Results by DOI
  2. ★, Common tissue-specific expressions and regulatory factors of c-KIT isoforms with and without GNNK and GNSK sequences across five mammals, PLOS ONE, 21(1), 20260120
    Link to Paper Search Results by DOI
  3. ★, Extrinsic heterogeneity: Collectivity in isotropic conformational fluctuations of chromosomes, BIOPHYSICAL JOURNAL, 124(13), 2195-2208, 20250701
    Link to Paper Search Results by DOI
  4. ★, Potential multiple disease progression pathways in female patients with Alzheimer's disease inferred from transcriptome and epigenome data of the dorsolateral prefrontal cortex, PLOS ONE, 20(3), 20250318
    Link to Paper Search Results by DOI
  5. CRISPR-Cas9-Mediated Gene Knockout in a Non-Model Sea Urchin, Heliocidaris crassispina, ZOOLOGICAL SCIENCE, 41(2), 159-166, 202404
    Link to Paper Search Results by DOI
  6. ★, Assembly of continuous high-resolution draft genome sequence of Hemicentrotus pulcherrimus using long-read sequencing, DEVELOPMENT GROWTH & DIFFERENTIATION, 66(4), 297-304, 202405
    Link to Paper Search Results by DOI
  7. ★, Mathematical model of structural changes in nuclear speckle, BIOPHYSICS AND PHYSICOBIOLOGY, 20(2), 2023
    Link to Paper Search Results by DOI
  8. ★, Possibilities of skin coat color-dependent risks and risk factors of squamous cell carcinoma and deafness of domestic cats inferred via RNA-seq data, GENES TO CELLS, 28(12), 893-905, 202312
    Link to Paper Search Results by DOI
  9. ★, The crucial role of CTCF in mitotic progression during early development of sea urchin, DEVELOPMENT GROWTH & DIFFERENTIATION, 65(7), 395-407, 202309
    Link to Paper Search Results by DOI
  10. ★, Formation of Small-World Network Containing Module Networks in Globally and Locally Coupled Map System with Changes in Global Connection with Time Delay Effects, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 92(3), 20230214
    Link to Paper Search Results by DOI
  11. Identification of aberrant transcription termination at specific gene loci with DNA hypomethylated transcription termination sites caused by DNA methyltransferase deficiency, GENES & GENETIC SYSTEMS, 97(3), 139-152, 202206
    Link to Paper Search Results by DOI
  12. Methylome data derived from maternal-zygotic DNA methyltransferase 3aa(-/-) zebrafish, DATA IN BRIEF, 44, 202210
    Link to Paper Search Results by DOI
  13. Molecular dynamics analysis of biomolecular systems including nucleic acids, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
    Link to Paper Search Results by DOI
  14. ★, Epigenetic-structural changes in X chromosomes promote Xic pairing during early differentiation of mouse embryonic stem cells, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
    Link to Paper Search Results by DOI
  15. Ants Alter Collective Behavior After Feeding and Generate Shortcut Paths on a Two-Dimensional Foraging Area, FRONTIERS IN PHYSICS, 10, 20220511
    Link to Paper Search Results by DOI
  16. ★, Partial exogastrulation due to apical-basal polarity of F-actin distribution disruption in sea urchin embryo by omeprazole, GENES TO CELLS, 27(6), 392-408, 202206
    Link to Paper Search Results by DOI
  17. ★, Mathematical model of chromosomal dynamics during DNA double strand break repair in budding yeast, BIOPHYSICS AND PHYSICOBIOLOGY, 19, 2022
    Link to Paper Search Results by DOI
  18. ★, Ribosomal protein L5 facilitates rDNA-bundled condensate and nucleolar assembly, LIFE SCIENCE ALLIANCE, 5(7), 202207
    Link to Paper Search Results by DOI
  19. ★, Self-Organization of Diverse Directional Hierarchical Networks in Simple Coupled Maps with Connection Changes, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 91(2), 20220215
    Link to Paper Search Results by DOI
  20. Structural dynamics of DNA depending on methylation pattern, PHYSICAL REVIEW E, 103(1), 20210111
    Link to Paper Search Results by DOI
  21. ★, Spontaneous Organizations of Diverse Network Structures in Coupled Logistic Maps with a Delayed Connection Change, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 89(11), 20201115
    Link to Paper Search Results by DOI
  22. ★, Ultrasensitive Change in Nucleosome Binding by Multiple Phosphorylations to the Intrinsically Disordered Region of the Histone Chaperone FACT, JOURNAL OF MOLECULAR BIOLOGY, 432(16), 4637-4657, 20200724
    Link to Paper Search Results by DOI
  23. ★, Affinity of rhodopsin to raft enables the aligned oligomer formation from dimers: Coarse-grained molecular dynamics simulation of disk membranes, PLOS ONE, 15(2), 20200207
    Link to Paper Search Results by DOI
  24. Simple Particle Model for Low-Density Granular Flow Interacting with Ambient Fluid, GEOSCIENCES, 10(2), 202002
    Link to Paper Search Results by DOI
  25. Histone Tail Dynamics in Partially Disassembled Nucleosomes During Chromatin Remodeling, FRONTIERS IN MOLECULAR BIOSCIENCES, 6, 20191128
    Link to Paper Search Results by DOI
  26. Establishment of knockout adult sea urchins by using a CRISPR-Cas9 system, DEVELOPMENT GROWTH & DIFFERENTIATION, 61(6), 378-388, 201908
    Link to Paper Search Results by DOI
  27. Verification of mathematical models of response threshold through statistical characterisation of the foraging activity in ant societies, SCIENTIFIC REPORTS, 9, 20190620
    Link to Paper Search Results by DOI
  28. Diverse stochasticity leads a colony of ants to optimal foraging, JOURNAL OF THEORETICAL BIOLOGY, 465, 7-16, 20190321
    Link to Paper Search Results by DOI
  29. ★, Insulator Activities of Nucleosome-Excluding DNA Sequences without Bound Chromatin Looping Proteins, JOURNAL OF PHYSICAL CHEMISTRY B, 123(5), 1035-1043, 20190207
    Link to Paper Search Results by DOI
  30. ★, Torsional Turning Motion of Chromosomes as an Accelerating Force to Align Homologous Chromosomes during Meiosis, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 88(2), 20190215
    Link to Paper Search Results by DOI
  31. Chromosomal Abnormalities in Human Lymphocytes after Computed Tomography Scan Procedure, RADIATION RESEARCH, 190(4), 424-432, 201810
    Link to Paper Search Results by DOI
  32. ★, Broad distribution spectrum from Gaussian to power law appears in stochastic variations in RNA-seq data, SCIENTIFIC REPORTS, 8, 20180529
    Link to Paper Search Results by DOI
  33. Reciprocating Motion of a Self-Propelled Rotor Induced by Forced Halt and Release Operations, JOURNAL OF PHYSICAL CHEMISTRY C, 122(6), 3482-3487, 20180215
    Link to Paper Search Results by DOI
  34. Dynamic changes in the interchromosomal interaction of early histone gene loci during development of sea urchin, JOURNAL OF CELL SCIENCE, 130(24), 4097-4107, 201712
    Link to Paper Search Results by DOI
  35. ★, Excluded volume effect enhances the homology pairing of model chromosomes, IEICE NONLINEAR THEORY AND ITS APPLICATIONS, 7(2), 66-75, 2016
    Link to Paper Search Results by DOI
  36. ★, The 1-Particle-per-k-Nucleotides (1PkN) Elastic Network Model of DNA Dynamics with Sequence-Dependent Geometry, FRONTIERS IN PHYSIOLOGY, 8, 20170314
    Link to Paper Search Results by DOI
  37. ★, Prediction of nucleosome positioning by the incorporation of frequencies and distributions three different nucleotide segment lengths into a general pseudo k-tuple nucleotide composition, BIOINFORMATICS, 33(1), 42-48, 20170101
    Link to Paper Search Results by DOI
  38. A new application of the phase-field method for understanding the mechanisms of nuclear architecture reorganization, JOURNAL OF MATHEMATICAL BIOLOGY, 74(1-2), 333-354, 201701
    Link to Paper Search Results by DOI
  39. The Flux of Euglena gracilis Cells Depends on the Gradient of Light Intensity, PLOS ONE, 11(12), 20161229
    Link to Paper Search Results by DOI
  40. Risk stratification of ventricular fibrillation in Brugada syndrome using noninvasive scoring methods, HEART RHYTHM, 13(10), 1947-1954, 201610
    Link to Paper Search Results by DOI
  41. ★, Cilia play a role in breaking left-right symmetry of the sea urchin embryo, GENES TO CELLS, 21(6), 568-578, 201606
    Link to Paper Search Results by DOI
  42. ★, Simple Elastic Network Models for Exhaustive Analysis of Long Double-Stranded DNA Dynamics with Sequence Geometry Dependence, PLOS ONE, 10(12), 20151201
    Link to Paper Search Results by DOI
  43. ★, Noise-plasticity correlations of gene expression in the multicellular organism Arabidopsis thaliana, JOURNAL OF THEORETICAL BIOLOGY, 387, 13-22, 20151221
    Link to Paper Search Results by DOI
  44. ★, Nuclear dynamical deformation induced hetero- and euchromatin positioning, PHYSICAL REVIEW E, 92(3), 20150914
    Link to Paper Search Results by DOI
  45. Deterioration of the circadian variation of heart rate variability in Brugada syndrome may contribute to the pathogenesis of ventricular fibrillation, JOURNAL OF CARDIOLOGY, 64(2), 133-138, 201408
    Link to Paper Search Results by DOI
  46. ★, Segregation and phase inversion of strongly and weakly fluctuating Brownian particle mixtures and a chain of such particle mixtures in spherical containers, PHYSICAL REVIEW E, 90(4), 20141017
    Link to Paper Search Results by DOI
  47. Localized Bioconvection Patterns and Their Initial State Dependency in Euglena gracilis Suspensions in an Annular Container, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 83(4), 201404
    Link to Paper Search Results by DOI
  48. Motion with Memory of a Self-Propelled Object, JOURNAL OF PHYSICAL CHEMISTRY C, 117(46), 24490-24495, 20131121
    Link to Paper Search Results by DOI
  49. Collective motion of symmetric camphor papers in an annular water channel, PHYSICAL REVIEW E, 88(1), 20130730
    Link to Paper Search Results by DOI
  50. ★, Influences of Excluded Volume of Molecules on Signaling Processes on the Biomembrane, PLOS ONE, 8(5), 20130502
    Link to Paper Search Results by DOI
  51. Stability of transverse dunes against perturbations: A theoretical study using dune skeleton model, AEOLIAN RESEARCH, 9, 63-68, 201306
    Link to Paper Search Results by DOI
  52. Collective Motion and Phase Transitions of Symmetric Camphor Boats, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 81(7), 201207
    Link to Paper Search Results by DOI
  53. Swarming of self-propelled camphor boats, PHYSICAL REVIEW E, 85(5), 20120507
    Link to Paper Search Results by DOI
  54. Segregation-pattern reorientation of a granular mixture on a horizontally oscillating tray, PHYSICAL REVIEW E, 85(4), 20120416
    Link to Paper Search Results by DOI
  55. Bifurcation Analysis of the Transition of Dune Shapes under a Unidirectional Wind, PHYSICAL REVIEW LETTERS, 108(15), 20120412
    Link to Paper Search Results by DOI
  56. Effective stochastic resonance of coupled excitable elements under noise of unequal amplitude, PHYSICAL REVIEW E, 84(2), 20110824
    Link to Paper Search Results by DOI
  57. Localized Bioconvection of Euglena Caused by Phototaxis in the Lateral Direction, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 80(6), 201106
    Link to Paper Search Results by DOI
  58. Effective stochastic resonance under noise of heterogeneous amplitude, PHYSICAL REVIEW E, 82(5), 20101117
    Link to Paper Search Results by DOI
  59. Saddle-node bifurcation to jammed state for quasi-one-dimensional counter-chemotactic flow, PHYSICAL REVIEW E, 82(2), 20100721
    Link to Paper Search Results by DOI
  60. Three-Dimensional Dune Skeleton Model as a Coupled Dynamical System of Two-Dimensional Cross Sections, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 79(6), 201006
    Link to Paper Search Results by DOI
  61. Collective behavior of inanimate boats, PHYSICAL REVIEW E, 81(5), 201005
    Link to Paper Search Results by DOI
  62. ★, Discreteness-induced slow relaxation in reversible catalytic reaction networks, PHYSICAL REVIEW E, 81(5), 201005
    Link to Paper Search Results by DOI
  63. ★, Ubiquitous glassy" relaxation in catalytic reaction networks", PHYSICAL REVIEW E, 80(4), 200910
    Link to Paper Search Results by DOI
  64. ★, Self-organized criticality of a catalytic reaction network under flow, PHYSICAL REVIEW E, 80(1), 200907
    Link to Paper Search Results by DOI
  65. Counter Chemotactic Flow in Quasi-One-Dimensional Path, JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 78(7), 200907
    Link to Paper Search Results by DOI
  66. ★, Input-dependent wave propagations in asymmetric cellular automata: Possible behavior forward loop in biological reaction network, MATHEMATICAL BIOSCIENCES AND ENGINEERING, 5(3), 419-427, 200807
    Link to Paper Search Results by DOI
  67. ★, Network structure formation in pulsating particle populations, PHYSICAL REVIEW E, 76(5), 200711
    Link to Paper Search Results by DOI
  68. ★, Discreteness-induced transition in catalytic reaction networks, PHYSICAL REVIEW E, 76(4), 200710
    Link to Paper Search Results by DOI

Invited Lecture, Oral Presentation, Poster Presentation

  1. Insulator Activities of Nucleosome-Excluding DNA Sequences Without Chromatin Loop Form, Akinori Awazu, Yuki Matsushima, Naoaki Sakamo, The 57th Annual Meeting of Biophysical Society of Japan, 2019, With Invitation, English
  2. Chromatin segregation induced by nucleus envelope dynamical deformities, Akinori Awazu, THE 3RD HIROSHIMA INTERNATIONAL SYMPOSIUM ON FUTURE SCIENCE "FRONTIERS IN BIOIMAGING BASED LIFE SCIENCE", 2018, With Invitation, English
  3. Novel statistical model of fluctuating gene expression levels of Arabidopsis thaliana, Akinori Awazu, Atsushi J Nagano, The 55th Annual Meeting of the Biophysical Society of Japan, 2017, With Invitation, English
  4. Mathematical model of spatiotemporal dynamics of plant hormones responsible for plant stress response, 2020/09/16, Without Invitation, English
  5. A mathematical model of chromosomal dynamics in budding yeast during DNA double strand break, 2020/09/16, Without Invitation, English
  6. Analysis of physical properties and functionalities of ArsInsC and DNA repeat sequences, 2020/09/16, Without Invitation, English
  7. Self organized netowrk structures in coupled dynamical system with connection palasticity inspired by cerebral nervous system, 2020/09/16, Without Invitation, English
  8. The dynamics of chromosomes on early differentiation stage from ES cell, 2020/09/16, Without Invitation, English
  9. Modeling of sea urchin gastrulation based on cytoskeleton imaging, Kaichi Watanabe, Yuta Kurose, Yuhei Yasui, Naoaki Sakamoto, Akinori Awazu, 2020/09/16, Without Invitation, English
  10. Dynamic and cell specific changes in intranuclear chromosomal structures during early development of sea urchin, Yuhei Yasui, Ayaka Sugiyama , Naoaki Sakamoto , Akinori Awazu, 2020/09/16, Without Invitation, English

Awards

  1. 2024/06/21, Development, Growth & Differentiation Young Invesitigator Paper Award 2024, Japanese Society of Developmental Biologists, The crucial role of CTCF in mitotic progression during early development of sea urchin.
  2. 2023/11/15, Biophysics and Physicobiology 10th Editors' Choice Award, Biophysical Society of Japan, Epigenetic-structural changes in X chromosomes promote Xic pairing during early differentiation of mouse embryonic stem cells.

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2024, 2026
  2. Moonshot R&D Program, 2024//5//2, 2027//3//3
  3. Moonshot R&D Program, 2024//5//2, 2027//3//3
  4. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  5. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
  6. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019
  7. KAKENHI, 2014, 2015
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  8. KAKENHI, 2013, 2014
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  9. KAKENHI, 2012, 2013
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  10. KAKENHI, Collective motion of self-propelled particles, 2011, 2012
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  11. KAKENHI, Dynamics and Functions of Diverse Multi-Element Systems Accompanied by Fluctuation, 2010, 2012
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  12. KAKENHI, Study of biological functions through formulation of the response theory of reaction network system, 2007, 2010
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