KAZUNORI KUME

Last Updated :2020/09/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
E-mail
kume513hiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Doctor of Science, Hiroshima University
  • Master of Science, Hiroshima University

Research Fields

  • Biology;Biological Science;Cell biology
  • Agricultural sciences;Agricultural chemistry;Applied biochemistry

Educational Activity

Course in Charge

  1. 2020, Undergraduate Education, Second Semester, Basic Experiments in Chemistry
  2. 2020, Undergraduate Education, Second Semester, Experiments on Biotechnology II
  3. 2020, Undergraduate Education, 3Term, Molecular Bioinformatics
  4. 2020, Graduate Education (Master's Program) , First Semester, Seminar on Molecular Biotechnology
  5. 2020, Graduate Education (Master's Program) , Second Semester, Seminar on Molecular Biotechnology
  6. 2020, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
  7. 2020, Graduate Education (Master's Program) , 1Term, English Presentation Methods in Science and Technology
  8. 2020, Graduate Education (Master's Program) , 4Term, societal implementation of life science
  9. 2020, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
  10. 2020, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
  11. 2020, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
  12. 2020, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
  13. 2020, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B
  14. 2020, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biotechnology
  15. 2020, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
  16. 2020, Graduate Education (Master's Program) , 1Term, Advanced Technologies for Life Science
  17. 2020, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar A
  18. 2020, Graduate Education (Master's Program) , 3Term, Biomedical Science Seminar B
  19. 2020, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar C
  20. 2020, Graduate Education (Doctoral Program) , 3Term, Biomedical Science Seminar D

Research Activities

Academic Papers

  1. Casein Kinase 1 gamma Ensures Monopolar Growth Polarity under Incomplete DNA Replication Downstream of Cds1 and Calcineurin in Fission Yeast, MOLECULAR AND CELLULAR BIOLOGY, 35(9), 1533-1542, 201505
  2. Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application for a positive screening for drugs inhibiting calcineurin, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 79(5), 790-794, 20150504
  3. Isolation of a spontaneous cerulenin-resistant sake yeast with both high ethyl caproate-producing ability and normal checkpoint integrity, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 79(7), 1191-1199, 20150703
  4. The essential function of Rrs1 in ribosome biogenesis is conserved in budding and fission yeasts, YEAST, 32(9), 607-614, 201509
  5. Casein kinase 1 gamma acts as a molecular switch for cell polarization through phosphorylation of the polarity factor Tea1 in fission yeast, GENES TO CELLS, 20(12), 1046-1058, 201512
  6. Late-maturing cooking rice Sensyuraku has excellent properties, equivalent to sake rice, for high-quality sake brewing, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 78(11), 1954-1962, 20141102
  7. Ras/cAMP-dependent Protein Kinase (PKA) Regulates Multiple Aspects of Cellular Events by Phosphorylating the Whi3 Cell Cycle Regulator in Budding Yeast, JOURNAL OF BIOLOGICAL CHEMISTRY, 288(15), 10558-10566, 20130412
  8. Fission Yeast Leucine-Rich Repeat Protein Lrp1 Is Essential for Cell Morphogenesis as a Component of the Morphogenesis Orb6 Network (MOR), BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(5), 1086-1091, 201305
  9. Evidence of Antagonistic Regulation of Restart from G(1) Delay in Response to Osmotic Stress by the Hog1 and Whi3 in Budding Yeast, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(10), 2002-2007, 201310
  10. Polishing Properties of Sake Rice Koshitanrei for High-Quality Sake Brewing, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(10), 2160-2165, 201310
  11. Isolation of a Non-Urea-Producing Sake Yeast Strain Carrying a Discriminable Molecular Marker, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 77(12), 2505-2509, 201312
  12. Calcineurin ensures a link between the DNA replication checkpoint and microtubule-dependent polarized growth., Calcineurin ensures a link between the DNA replication checkpoint and microtubule-dependent polarized growth., 13(3), 234-U357, 2011
  13. Sake Lees Fermented with Lactic Acid Bacteria Prevents Allergic Rhinitis-Like Symptoms and IgE-Mediated Basophil Degranulation, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 75(1), 140-144, 201101
  14. Implication of Ca2+ in the Regulation of Replicative Life Span of Budding Yeast, JOURNAL OF BIOLOGICAL CHEMISTRY, 286(33), 28681-28687, 20110819
  15. Fission Yeast Germinal Center (GC) Kinase Ppk11 Interacts with Pmo25 and Plays an Auxiliary Role in Concert with the Morphogenesis Orb6 Network (MOR) in Cell Morphogenesis, JOURNAL OF BIOLOGICAL CHEMISTRY, 285(45), 35196-35205, 20101105
  16. The mitosis-to-interphase transition is coordinated by cross talk between the SIN and MOR pathways in Schizosaccharomyces pombe, JOURNAL OF CELL BIOLOGY, 190(5), 793-805, 20100906
  17. A method for Pmo25-associated kinase assay in fission yeast: The activity is dependent on two GC kinases Nak1 and Sid1, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 71(2), 615-617, 200702
  18. The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint, MOLECULAR BIOLOGY OF THE CELL, 17(3), 1421-1435, 200603
  19. Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis, EMBO JOURNAL, 24(17), 3012-3025, 20050907
  20. Mal3, the fission yeast EB1 homologue, cooperates with Bub1 spindle checkpoint to prevent monopolar attachment, EMBO REPORTS, 6(12), 1194-1200, 200512
  21. Effect of ethanol on cell growth of budding yeast: Genes that are important for cell growth in the presence of ethanol, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 68(4), 968-972, 200404
  22. Search for kinases related to transition of growth polarity in fission yeast., BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 74(5), 2010
  23. Identification of a mutation causing a defective spindle assembly checkpoint in high ethyl caproate-producing sake yeast strain K1801, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 80(8), 1657-1662, 201608
  24. Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5, ELIFE, 5, 20160730
  25. Stimulating S-adenosyl-L-methionine synthesis extends lifespan via activation of AMPK, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(42), 11913-11918, 20161018
  26. A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control, PLOS GENETICS, 13(5), 201705
  27. Identification of three signaling molecules required for calcineurin-dependent monopolar growth induced by the DNA replication checkpoint in fission yeast, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 491(4), 883-889, 20170930
  28. A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast, MOLECULAR BIOLOGY OF THE CELL, 28(25), 3647-3659, 20171201
  29. Role of nucleocytoplasmic transport in interphase microtubule organization in fission yeast, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 503(2), 1160-1167, 20180905
  30. Evidence of antagonistic regulation of restart from G(1) delay in response to osmotic stress by the Hog1 and Whi3 in budding yeast., Evidence of antagonistic regulation of restart from G(1) delay in response to osmotic stress by the Hog1 and Whi3 in budding yeast., 77(10), 2013
  31. Fission yeast leucine-rich repeat protein Lrp1 is essential for cell morphogenesis as a component of the morphogenesis Orb6 network (MOR)., Fission yeast leucine-rich repeat protein Lrp1 is essential for cell morphogenesis as a component of the morphogenesis Orb6 network (MOR)., 77(5), 2013
  32. Ras/cAMP-dependent protein kinase (PKA) regulates multiple aspects of cellular events by phosphorylating the Whi3 cell cycle regulator in budding yeast., Ras/cAMP-dependent protein kinase (PKA) regulates multiple aspects of cellular events by phosphorylating the Whi3 cell cycle regulator in budding yeast., 288(15), 2013
  33. Implication of Ca2+ in the regulation of replicative life span of budding yeast., Implication of Ca2+ in the regulation of replicative life span of budding yeast., 286(33), 2011

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, 2014, 2016
  2. KAKENHI, Cell morphogenesis network regulates coordination between cell morphogenesis and cell growth, 2009, 2011
  3. KAKENHI, 2007, 2008
  4. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2017, 2019