TAKENORI ISHIDA

Last Updated :2023/06/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor or Lecturer
E-mail
tishishihiroshima-u.ac.jp
Self-introduction
Every substance has a surface. My research connects biotechnology and different fields by using biomolecules (proteins and peptides) that interact with the surface. Specifically, we are developing a technology to easily detect asbestos using proteins that bind to the surface of asbestos fibers. We have discovered peptides that bind to the surface (lipid bilayer) of exosomes, which has the potential to be used for cancer diagnosis and regenerative medicine, and are developing exosome purification technologies using the peptides.

Basic Information

Major Professional Backgrounds

  • 2007/04/01, 2008/03/31, Strategic Basic Research Programs Japan Science and Technology Agency, Postdoctoral fellow
  • 2008/04/01, 2010/01/31, Hiroshima University, Postdoctoral fellow
  • 2010/02/01, 2017/05/31, Hiroshima University, Graduate School of Advanced Sciences of Matter, Assistant Professor (Special Appointment)
  • 2017/06/01, 2019/03/31, Hiroshima University, Graduate School of Advanced Sciences of Matter, Lecturer
  • 2019/04/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Lecturer

Educational Backgrounds

  • Hiroshima University, 1998/04, 2002/03
  • Hiroshima University, 2002/04, 2004/03
  • Hiroshima University, 2004/04, 2007/03

Academic Degrees

  • Master, Hiroshima University
  • Doctor of Engineering, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Engineering : Cluster 3(Applied Chemistry, Biotechnology and Chemical Engineering) : Program of Biotechnology
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology

Research Fields

  • Agricultural sciences;Agricultural chemistry;Applied biochemistry

Research Keywords

  • Asbestos, Exosome, Biosensing, Peptide, Protein Engineering

Affiliated Academic Societies

  • The Society for Biotechnology, Japan
  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • The Molecular Biology Society of Japan

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, First Semester, Training of Biotechnology I
  2. 2023, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
  3. 2023, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
  4. 2023, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
  5. 2023, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B

Research Activities

Academic Papers

  1. ★, Molecular engineering of a fluorescent bioprobe for sensitive and selective detection of amphibole asbestos, PLoS ONE, 8(9), e76231, 20130927
  2. ★, Inhibition of quorum sensing in Pseudomonas aeruginosa by N-acyl cyclopentylamides, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(10), 3183-3188, 200705
  3. ★, Detection of chrysotile asbestos by using a chrysotile-binding protein, BIOTECHNOLOGY AND BIOENGINEERING, 99(2), 285-289, 20080201
  4. ★, Selective Detection of Airborne Asbestos Fibers Using Protein-Based Fluorescent Probes, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 44(2), 755-759, 20100115
  5. ★, Evaluation of Sensitivity of Fluorescence-Based Asbestos Detection by Correlative Microscopy, JOURNAL OF FLUORESCENCE, 22(1), 357-363, 2012
  6. Development of an automated asbestos counting software based on fluorescence microscopy, ENVIRONMENTAL MONITORING AND ASSESSMENT, 187(1), 2015
  7. Differential Counting of Asbestos Using Phase Contrast and Fluorescence Microscopy, ANNALS OF OCCUPATIONAL HYGIENE, 60(9), 1104-1115, 2016
  8. ★, Rapid on-site detection of airborne asbestos fibers and potentially hazardous nanomaterials using fluorescence microscopy-based biosensing, BIOTECHNOLOGY JOURNAL, 11(6), 757-767, 20160524
  9. Synthetic Phosphorus Metabolic Pathway for Biosafety and Contamination Management of Cyanobacterial Cultivation, ACS SYNTHETIC BIOLOGY, 7(9), 2189-2198, 201809
    Link to Paper Search Results by DOI
  10. ★, Live-cell imaging of macrophage phagocytosis of asbestos fibers under updates fluorescence microscopy, GENES AND ENVIRONMENT, 41, 20190605
    Link to Paper Search Results by DOI
  11. ★, Application of peptides with an affinity for phospholipid membranes during the automated purification of extracellular vesicles, SCIENTIFIC REPORTS, 10(1), 20201030
    Link to Paper Search Results by DOI

Patented

  1. Patent, 6712383, 2020/06/03

External Funds

Acceptance Results of Competitive Funds

  1. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2012/11/01, 2013/10/31
  2. Adaptable and Seamless Technology transfer Program through targetdriven R&D, 2015/01/01, 2015/12/31
  3. 2013/04/01, 2016/03/31
  4. KAKENHI(Grant-in-Aid for Scientific Research (C)), 2019, 2021

Social Activities

History as Peer Reviews of Academic Papers

  1. 2019, Cell Biology and Toxicology, Others