NORIFUMI SHIGEMOTO

Last Updated :2025/07/05

Affiliations, Positions
Translational Research Center, Associate Professor
Web Site
https://www.hiroshima-u.ac.jp/trc
E-mail
trcshigehiroshima-u.ac.jp
Self-introduction
I will work to develop as a research university through efforts to improve R & D.

Basic Information

Educational Backgrounds

  • Hiroshima University, Graduate School of Biomedical Sciences, Japan, 2009/04, 2013/05
  • Hiroshima University, Faculty of Medicine, Japan, 1996/04, 2002/03

Academic Degrees

  • Doctor of Philosophy in Medical Science, Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Digestive surgery
  • Medicine,dentistry, and pharmacy;Clinical internal medicine;Infectious disease medicine
  • Medicine,dentistry, and pharmacy;Basic medicine;Bacteriology (including mycology)

Research Keywords

  • Emerging and reemerging infectious diseases
  • Surgical site infection
  • Translational Research
  • Antimicrobial resistance

Affiliated Academic Societies

  • Japan Society of Clinical Trials and Research, 2019/12
  • The Japanese Society of Clinical Pharmacology and Therapeutics, 2021/08
  • Japan Surgical Society
    Related URL
  • The Japanese Society of Gastroenterological Surgery
    Related URL
  • The Japanese Association for Infectious Diseases
    Related URL
  • Japan Society for Surgical Infection
    Related URL
  • Japanese Society of Chemotherapy
    Related URL
  • Japanese Society of Travel and Health
    Related URL
  • The Japan Society of Coloproctology
    Related URL
  • Japanese Society for Bacteriology
    Related URL
  • The Japanese Association for Thoracic Surgery, 2002/05, 2002/05
    Related URL
  • The Japanese Society of Pediatric Surgeons, 2002/05, 2002/05
  • Japan Surgical Association, 2003, 2003
  • Japan Society of Clinical Oncology
    Related URL
  • Japanese Association for Acute Medicine
    Related URL
  • Japanese Society for Abdominal Emergency Medicine
  • The Japanese Association for Surgery of Trauma
    Related URL
  • Japanese Society of Medical Oncology
    Related URL
  • The Japanese Society for Clinical Microbiology
  • Japanese Society for Infection Prevention and Control
    Related URL
  • Japanese Society of Clinical Studies on Intestinal Microflora
  • Japanese Breast Cancer Society

Educational Activity

Course in Charge

  1. 2025, Graduate Education (Master's Program) , First Semester, Lecture on Biodesign A1
  2. 2025, Graduate Education (Master's Program) , 2Term, Lecture on Translational Research A
  3. 2025, Graduate Education (Master's Program) , 4Term, Lecture on Translational Research B
  4. 2025, Undergraduate Education, Year, Systemic Disease Control
  5. 2025, Graduate Education (Master's Program) , 1Term, Seminar on Global Infectious Diseases

Research Activities

Academic Papers

  1. Fosfomycin as salvage therapy for persistent methicillin-resistant Staphylococcus aureus bacteremia: A case series and review of the literature, JOURNAL OF INFECTION AND CHEMOTHERAPY, 30(4), 352-356, 202404
    Link to Paper Search Results by DOI
  2. A case of bacteremia caused by Dialister micraerophilus with Enterocloster clostridioformis and Eggerthella lenta in a patient with pyometra, BMC INFECTIOUS DISEASES, 24(1), 20240124
    Link to Paper Search Results by DOI
  3. Clinical characteristics of extrapulmonary nontuberculous mycobacteria infections in comparison with pulmonary infections: A single-center, retrospective study in Japan, JOURNAL OF INFECTION AND CHEMOTHERAPY, 29(9), 875-881, 202309
    Link to Paper Search Results by DOI
  4. Virtual reality as a learning tool for improving infection control procedures, AMERICAN JOURNAL OF INFECTION CONTROL, 51(2), 129-134, 202302
    Link to Paper Search Results by DOI
  5. Viable SARS-CoV-2 detected in the air of hospital rooms of patients with COVID-19 with an early infection, INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 126, 73-78, 202301
    Link to Paper Search Results by DOI
  6. Indwelling catheterization, renal stones, and hydronephrosis are risk factors for symptomatic Staphylococcus aureus-related urinary tract infection, WORLD JOURNAL OF UROLOGY, 39(2), 511-516, 2021
  7. Ceftolozane-Tazobactam Pharmacokinetics in the Abdominal Tissue of Patients Undergoing Lower Gastrointestinal Surgery: Dosing Considerations Based on Site-Specific Pharmacodynamic Target Attainment, INFECTIOUS DISEASES AND THERAPY, 12(1), 193-207, 202301
  8. Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review, INTERNAL MEDICINE, 62(3), 431-437, 2022
    Link to Paper Search Results by DOI
  9. A multicenter study to investigate the positive rate of SARS-CoV-2 in middle ear and mastoid specimens from otologic surgery patients, AURIS NASUS LARYNX, 50(2), 285-291, 202304
    Link to Paper Search Results by DOI
  10. Prevalence of Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum detection in urine and respiratory tract samples in Hiroshima, Japan, HELIYON, 9(3), 202303
    Link to Paper Search Results by DOI
  11. Pharmacokinetics of cefmetazole in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients scheduled for lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment, JOURNAL OF INFECTION AND CHEMOTHERAPY, 29(3), 309-315, 202303
    Link to Paper Search Results by DOI
  12. Pharmacokinetics of flomoxef in plasma, peritoneal fluid, peritoneum, and subcutaneous adipose tissue of patients undergoing lower gastrointestinal surgery: Dosing considerations based on site-specific pharmacodynamic target attainment, JOURNAL OF INFECTION AND CHEMOTHERAPY, 29(2), 186-192, 202302
    Link to Paper Search Results by DOI
  13. Clinical characteristics of Actinotignum schaalii bacteremia in a Japanese tertiary hospital, ANAEROBE, 77, 202210
    Link to Paper Search Results by DOI
  14. Duration of infectious viral shedding in patients with mild to moderate COVID-19 treated with REGN-CoV2?, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(7), 912-917, 202207
    Link to Paper Search Results by DOI
  15. Adverse reactions to the BNT162b2 and mRNA-1273 mRNA COVID-19 vaccines in Japan, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(4), 576-581, 202204
    Link to Paper Search Results by DOI
  16. Vertebral osteomyelitis caused by Mycobacteroides abscessus subsp. abscessus resulting in spinal cord injury due to vertebral body fractures, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(2), 290-294, 202202
    Link to Paper Search Results by DOI
  17. Duration of infectious virus shedding in patients with severe coronavirus disease 2019 who required mechanical ventilation, JOURNAL OF INFECTION AND CHEMOTHERAPY, 28(1), 19-23, 202201
    Link to Paper Search Results by DOI
  18. Laboratory identification and clinical characteristics of Streptococcus bovis/Streptococcus equinus complex bacteremia: a retrospective, multicenter study in Hiroshima, Japan, BMC INFECTIOUS DISEASES, 21(1), 20211126
    Link to Paper Search Results by DOI
  19. Case Report: Emphysematous Pyelonephritis With a Congenital Giant Ureterocele, FRONTIERS IN PEDIATRICS, 9, 20211126
    Link to Paper Search Results by DOI
  20. Postoperative mediastinitis after cardiac surgery caused by Mycoplasma hominis: a case report, SURGICAL CASE REPORTS, 7(1), 20211123
    Link to Paper Search Results by DOI
  21. The effect of pulsed-xenon ultraviolet disinfection on surfaces contaminated with vancomycin-resistant Enterococci in a Japanese hospital, JOURNAL OF INFECTION AND CHEMOTHERAPY, 27(11), 1665-1668, 202111
    Link to Paper Search Results by DOI
  22. Combining pulsed xenon ultraviolet disinfection with terminal manual cleaning helps reduce the acquisition rate of methicillin-resistant Staphylococcus aureus, AMERICAN JOURNAL OF INFECTION CONTROL, 49(8), 1048-1051, 202108
    Link to Paper Search Results by DOI
  23. Clinical and microbiological characteristics of Eggerthella lenta bacteremia at a Japanese tertiary hospital, JOURNAL OF INFECTION AND CHEMOTHERAPY, 27(8), 1261-1264, 202108
    Link to Paper Search Results by DOI
  24. Methicillin-resistant Staphylococcus aureus contamination of hospital-use-only mobile phones and efficacy of 222-nm ultraviolet disinfection, AMERICAN JOURNAL OF INFECTION CONTROL, 49(6), 800-803, 202106
    Link to Paper Search Results by DOI
  25. Pilot study on the decontamination efficacy of an installed 222-nm ultraviolet disinfection device (Care222(TM)), with a motion sensor, in a shared bathroom, PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 34, 202106
    Link to Paper Search Results by DOI
  26. High incidence of postoperative silent venous thromboembolism in ulcerative colitis: a retrospective observational study, BMC SURGERY, 21(1), 20210519
    Link to Paper Search Results by DOI
  27. Complicated cutaneous leishmaniasis caused by an imported case of Leishmania tropica in Japan: a case report, TROPICAL MEDICINE AND HEALTH, 49(1), 20210306
    Link to Paper Search Results by DOI
  28. Effectiveness of 222-nm ultraviolet light on disinfecting SARS-CoV-2 surface contamination, AMERICAN JOURNAL OF INFECTION CONTROL, 49(3), 299-301, 202103
    Link to Paper Search Results by DOI
  29. Effect of intermittent irradiation and fluence-response of 222 nm ultraviolet light on SARS-CoV-2 contamination, PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 33, 202103
    Link to Paper Search Results by DOI
  30. Effectiveness of pulsed xenon ultraviolet disinfection for Clostridioides (Clostridium) difficile surface contamination in a Japanese hospital, AMERICAN JOURNAL OF INFECTION CONTROL, 49(1), 55-58, 202101
    Link to Paper Search Results by DOI
  31. Indwelling catheterization, renal stones, and hydronephrosis are risk factors for symptomatic Staphylococcus aureus-related urinary tract infection, WORLD JOURNAL OF UROLOGY, 39(2), 511-516, 202102
    Link to Paper Search Results by DOI
  32. Complete Nucleotide Sequence of the IncN Plasmid Encoding IMP-6 and CTX-M-2 from Emerging Carbapenem-Resistant Enterobacteriaceae in Japan, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59(2), 1356-1359, 201502
    Link to Paper Search Results by DOI
  33. Persistence and Epidemic Propagation of a Pseudomonas aeruginosa Sequence Type 235 Clone Harboring an IS26 Composite Transposon Carrying the bla(IMP-1) Integron in Hiroshima, Japan, 2005 to 2012, ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59(5), 2678-2687, 201505
    Link to Paper Search Results by DOI
  34. Complete Nucleotide Sequence of pKOI-34, an IncL/M Plasmid Carrying blaIMP-34 in Klebsiella oxytoca Isolated in Japan., Antimicrob Agents Chemother, 60(5), 3156-3162, 20160422
  35. Hand-assisted laparoscopic restorative proctocolectomy for ulcerative colitis, WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 8(8), 578-582, 20160827
    Link to Paper Search Results by DOI
  36. Two Cases of Severe Ulcerative Colitis with Colonic Dilatation Resolved with Tacrolimus Therapy., Case Rep Gastroenterol, 9(2), 272-277, 20150731
  37. Persistence and epidemic propagation of a Pseudomonas aeruginosa sequence type 235 clone harboring an IS26 composite transposon carrying the blaIMP-1 integron in Hiroshima, Japan, 2005 to 2012., Antimicrob Agents Chemother, 59(5), 2678-2687, 201505
  38. Complete nucleotide sequence of the IncN plasmid encoding IMP-6 and CTX-M-2 from emerging carbapenem-resistant Enterobacteriaceae in Japan., Antimicrob Agents Chemother, 59(2), 1356-1359, 201502
  39. Imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae producing OXA-181 in Japan., Antimicrob Agents Chemother, 59(2), 1379-1380, 201502
  40. Pharmacokinetics and pharmacodynamic target attainment of intravenous pazufloxacin in the bile of patients undergoing biliary pancreatic surgery., J Chemother, 26(5), 287-292, 201410
  41. Tripoli metallo-B-lactamase-1 (TMB-1)-producing Acinetobacter spp. with decreased resistance to imipenem in Japan., Antimicrob Agents Chemother, 58(4), 2477-2478, 2014
  42. The first case of septicemia caused by imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae., Ann Lab Med, 33(5), 383-385, 201309
  43. Meropenem resistance in imipenem-susceptible meropenem-resistant Klebsiella pneumoniae isolates not detected by rapid automated testing systems., J Clin Microbiol, 51(8), 2735-2738, 201310
  44. ★, A novel metallo-B-lactamase, IMP-34, in Klebsiella isolates with decreased resistance to imipenem., Diagn Microbiol Infect Dis, 76(1), 119-121, 201303
  45. Rapid detection of blaIMP-6 by amplification refractory mutation system., J Microbiol Methods, 88(1), 182-184, 201201
  46. ★, Emergence in Japan of an imipenem-susceptible, meropenem-resistant Klebsiella pneumoniae carrying blaIMP-6., Diagn Microbiol Infect Dis, 72(1), 109-112, 201201
  47. Prognostic impact of perioperative serum CA 19-9 levels in patients with resectable pancreatic cancer., Ann Surg Oncol, 17(9), 2321-2329, 201009
  48. [Antibiotic-resistant infectious thoracoabdominal aortic aneurysm; report of a case]., Kyobu Geka, 62(4), 333-335, 200908
  49. Usefulness of computed tomography as a preoperative diagnostic modality in a case with acute jejunogastric intussusception., J Gastrointest Surg, 11(8), 1078-1080, 200708

Invited Lecture, Oral Presentation, Poster Presentation

  1. Analysis of SSI surveillance with DPC data, Norifumi Shigemoto, Hiroki Kitagawa, Keitaro Omori, Yuko Kubo, Yuka Sano, Minako Mori, Hiroki Ohge, The 36th Annual Meeting of Japan Society for Surgical Infection, 2023/12/15, Without Invitation, Japanese, Japan Society for Surgical Infection, Kitakyushu City
  2. Clinical Immersion Initiatives in Corona Era, Norifumi Shigemoto, Daisuke Sugiyama, Tomohiko Kisaka, Matsuura Yasuyuki, Shigei Kan, Kazuhiro Tsuga, The 42nd Annual Scientific Meeting of the Japanese Society of Clinical Pharmacology and Therapeutics, 2021/12/11, Without Invitation, Japanese, apanese Society of Clinical Pharmacology and Therapeutics, Sendai
  3. Clinical Immersion Initiatives in Corona Era, Norifumi Shigemoto, ,Daisuke Sugiyama, Matsuura Yasuyuki, Shisei Kan, Tomohiko Kisaka, Kazuhiro Tsuga, 2022/09/10, Without Invitation, Japanese, Okayama
  4. Clinical Immersion Initiatives in Corona Era, Norifumi Shigemto, 2021/09/10, Without Invitation, Japanese

Awards

  1. 2011, Young Scientist Best Presentation Award, Japanese Society for Bacteriology - Chu Shikoku Brunch, Multiple Drug Resistant plasmid, pKPI-6, is carried by Imipenem-susceptible Meropenem-resistant Klebsiella pneumoniae(ISMRK)
  2. 2012, Award in the Category of Basic Research Conferred by the Director of the West Japan Branch of the Japanese Society of Chemotherapy., West Japan Branch of the Japanese Society of Chemotherapy., A novel metallo-β-lactamase, IMP-34, in Klebsiella isolates with decreased resistance to imipenem