広島大学

Basic Information

Major Professional Backgrounds

• 2019/04, 2019/09, Japan Society for the Promotion of Science, Special Postdoctoral Researcher（DC2)
• 2019/10, 2023/09, Kyushu University, Assistant Professor
• 2023/10/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Assistant Professor

Educational Backgrounds

• Hiroshima University, Graduate School of Biosphere Science , Japan, 2017/04, 2019/09
• Hiroshima University, Graduate School of Biosphere Science , Japan, 2015/04, 2017/03
• Hiroshima University, School of Applied Biological Science, Japan, 2011/04, 2015/03

Academic Degrees

• Hiroshima University
• Hiroshima University

Research Fields

• Agricultural sciences;Animal life science;Animal production science

Research Keywords

• Glucagon-like peptide
• Endocrinology
• Beef cows
• Dairy cows

Affiliated Academic Societies

• Warm Regional Society of Animal Science, Japan
• American Dairy Science Association (ADSA)
• Japanese Society of Animal Science

Educational Activity

Course in Charge

1. 2025, Undergraduate Education, Intensive, Laboratory Work in General Physics
2. 2025, Undergraduate Education, 3Term, Research Front of Bioresource Science
3. 2025, Undergraduate Education, 4Term, Environmental Animal Physiology
4. 2025, Undergraduate Education, 2Term, Reading of Foreign Literature in Applied Animal and Plant Schience
5. 2025, Undergraduate Education, 2Term, Production System in Livestock
6. 2025, Undergraduate Education, Intensive, Laboratory and Field Works in Animal Production II
7. 2025, Undergraduate Education, Second Semester, Graduation Thesis I
8. 2025, Undergraduate Education, First Semester, Graduation Thesis II
9. 2025, Undergraduate Education, Second Semester, Graduation Thesis III
10. 2025, Undergraduate Education, Intensive, (AIMS) Introduction Physiology of Domestic Animals
11. 2025, Undergraduate Education, Intensive, Introductory Physiology of Domestic Animals
12. 2025, Graduate Education (Doctoral Program) , 1Term, Research Plans in Life Science
13. 2025, Graduate Education (Master's Program) , 3Term, Smart Livestock Farming

Research Activities

Academic Papers

1. Effect of feeding sodium butyrate to beef female cows during pre- and post-partum period on concentrations of glucagon-like peptides in plasma and colostrum, Animal Science Journal, 95(1), e13961., 202405
2. Effect of Ca-octanoate supplementation on concentrations of ghrelin and ghrelin-related hormones in plasma and milk of beef cattle, Heliyon, 9(6), e16795, 202306
3. Estimation of silent phenotypes of calf antibiotic dysbiosis, Scientific Reports, 13, 6359, 202304
4. Effect of kraft pulp inclusion in calf starter on performance, health, and plasma concentration of glucagon-like peptide 2 in calves, Journal of Dairy Science, 106(6), 4443-4453, 202306
5. Development of a novel feeding method for Japanese black calves with thermophile probiotics at postweaning, Journal of Applied Microbiology, 132(5), 3870-3882, 202203
6. Rumen microbiota and its relation to fermentation in lactose-fed calves, Journal of Dairy Science, 104(10), 10744-10752, 202110
7. Glucagon-like peptide 2 (GLP-2) in bovine colostrum and transition milk, Heliyon, 7(5), e07046, 202105
8. Effects of starch concentration of close-up diets on rumen pH and plasma metabolite responses of dairy cows to grain challenges after calving, Journal of Dairy Science, 103(12), 11461-11471, 202012
9. Effects of feeding high volumes of milk replacer on reproductive performance and on concentrations of metabolites and hormones in blood of Japanese black heifer calves, Animal Science Journal, 92(1), e13505, 202101
10. Effects of pre- and postpartum dietary starch content on productivity, plasma energy metabolites, and serum inflammation indicators of dairy cows, Journal of Dairy Science, 104(4), 4362-4374, 202104
11. ★, Effects of feeding a moderate- or high-energy close-up diet to cows on response of newborn calves to milk replacer feeding and intravenous injection of glucagon-like peptide 1, Domestic Animal Endocrinology, 74(106528), 202101
12. Feeding colostrum or a 1:1 colostrum:milk mixture for 3 days postnatal increases small intestinal development and minimally influences plasma glucagon-like peptide-2 and serum insulin-like growth factor-1 concentrations in Holstein bull calves, Journal of Dairy Science, 103(5), 4236-4251, 202003
13. Effects of feeding a high- or moderate-starch prepartum diet to cows on newborn dairy heifer calf responses to intravenous glucose tolerance tests early in life, Journal of Dairy Science, 102(10), 8931-8940, 201910
14. The effect of tributyrin supplementation to milk replacer on plasma glucagon-like peptide 2 concentrations in pre-weaning calves, Animal Science Journal, 90(9), 1185-1192, 201909
15. ★, Effect of extended colostrum feeding on plasma glucagon-like peptide-1 concentration in newborn calves, Journal of Dairy Science, 102(5), 4619-4627, 201903
16. Effects of pulse-dose ruminal infusion of butyrate on plasma glucagon-like peptide 1 and 2 concentrations in dairy calves, Journal of Dairy Science, 102(3), 2254-2265, 201903
17. ★, Short communication: The effect of delayed colostrum feeding on plasma concentrations of glucagon-like peptide 1 and 2 in newborn calves, Journal of Dairy Science, 101(7), 6627-6631, 201807
18. ★, Plasma concentrations of glucagon-like peptide 1 and 2 in calves fed calf starters containing lactose, Journal of Dairy Science, 100(11), 9361-9371, 201709
19. Response of plasma glucagon-like peptide-2 to feeding pattern and intraruminal administration of volatile fatty acids in sheep, Domestic Animal Endocrinology, 60, 31-41, 201707
20. Effects of partial replacement of corn grain with lactose in calf starters on ruminal fermentation and growth performance, Journal of Dairy Science, 100(8), 6177-6186, 201708

Invited Lecture, Oral Presentation, Poster Presentation

1. Effect of feeding sodium butyrate to beef female cows during calving transition period on glucagon-like peptide 1 and 2 concentrations in colostrum and transition milk., Y. Inabu, H. Horike, H. Yamano, Y. Taguchi, S. Okada, T. Etoh, Y. Shiotsuka, R. Fujino, H. Takahashi, H. Horike, H. Yamano, Y. Taguchi, S. Okada, T. Etoh, Y. Shiotsuka, R. Fujino, H. Takahashi, International Symposium on Ruminant Physiology (ISRP), 2024, Without Invitation, English, Chicago, Secretion of glucagon-like peptide (GLP)-1 and 2 (GLP-2), a gut-derived peptide secreted from intestinal L-cells, is potently stimulated by dietary butyrate provision. Since the hormones contained in milk are transferred from the maternal blood circulation, an increase in circulating levels of GLP-1 and 2 due to dietary butyrate could result in increased levels in colostrum and transition milk. This study evaluated the effect of feeding beef cows with sodium butyrate (SB) during the late pregnancy and early post-partum periods on concentrations of GLP-1 and 2 in plasma, colostrum, and transition milk. Twelve Japanese Black female cows were fed hay and concentrate according to Japanese feeding standard for beef cows (2008) with (BUTY) or without (CON; n = 6 for each treatment) SB supplementation at 1.5% of the dietary dry matter from 60 d before the expected calving date (−60 d) to 4 d after calving. Blood samples were collected 1 h before feeding on −60, −30, and −7 d, and 0 (calving date), 1, 2, and 3 d after calving. Milk samples were collected immediately after blood sampling post-partum. Data were analyzed by ANOVA of JMP® 14 using fit model procedure. Plasma total cholesterol concentration was higher (P = 0.04) for the BUTY (151 ± 6.27 mg/dL) than for the CON (131 ± 6.27 mg/dL). In addition, plasma GLP-1 concentration was higher for the BUTY (0.82 ± 0.092 ng/mL) than for the CON (0.50 ± 0.092) at 3 d after calving (P < 0.05). On the other hand, plasma GLP-2 concentration was not affected by treatment. This study showed for the first time that GLP-1 and 2 were present in bovine colostrum at higher concentrations as compared to in plasma at −7 and 0 d (P < 0.01). On the other hand, treatment did not affect metabolite and hormone concentrations in colostrum and transition milk. In summary, feeding beef cows with SB during the calving transition period likely increases plasma GLP-1 concentrations post-partum without affecting the components of colostrum and transition milk.
2. Effects of exposure to white LED or electrodeless induction lamp on milk production performance and blood compositions of dairy cows, Inabu Y, Takakura Y, Shinohara Y, Sunadome M, Watanabe R, Kushibiki S, Obitsu T, Sugino T., ADSA Annual Meeting, 2024, Without Invitation, English
3. Effect of kraft pulp inclusion in calf starter on plasma concentration of glucagon-like peptide 2 in calves, Inabu Y, Kurosu K, Yasukawa Y, Hasunuma T, Ijima N, Funo H, Nishimura K, Kushibiki S, Kawashima K, Sugino T., International Symposium on Ruminant Physiology, 2019, Without Invitation, English
4. Effects of feeding moderate- or high-starch close-up diet to cows on response of newborn calves to intravenous injection of glucagon-like peptide 1, Inabu Y, Haisan J, Oba M, Sugino T., ADSA Annual Meeting, 2019, Without Invitation, English
5. Effects of pulse-dose intraruminal butyrate infusion on glucagon-like peptide 2 in dairy calves, Hatew B, Inabu Y, Sugino T, Steele M., ADSA Annual Meeting, 2018, Without Invitation, English
6. Effect of extended colostrum feeding on plasma glucagon-like peptide 1 concentration in newborn calves, Inabu Y, Pyo J, Pletts S, Steele M A, Sugino T., ADSA Annual Meeting, 2018, Without Invitation, English
7. Pulse-dose intraruminal butyrate infusion increases plasma glucagon-like peptide 2 in dairy calves, Hatew B, Inabu Y, Steele M A., Western Canadian Dairy Seminar, 2018, Without Invitation, English
8. Effect of extended colostrum feeding duration on gastrointestinal tract structural development of Holstein bull calves, Pyo J G, Pletts S I, Inabu Y, He Z, Haines D, Sugino T, Guan L L, Steele M A., Western Canadian Dairy Seminar, 2018, Without Invitation, English
9. Effect of lactose inclusion in the calf starter on starter intake, growth performance and digestive organ development, Inouchi K, Saegusa A, Inabu Y, Sugino T, Oba M., ASAS-ADSA-CSAS-WSASAS Joint Annual Meeting, 2016, Without Invitation, English
10. Plasma concentrations of glucagon-like peptide 1 and 2 in calves fed calf starters containing lactose, Inabu Y, Saegusa A, Inouchi K, Oba M, Sugino T., ASAS-ADSA-CSAS-WSASAS Joint Annual Meeting, 2016, Without Invitation, English
11. The effects of extended colostrum feeding on gastrointestinal tract growth of the neonatal dairy calf, Pyo J, Pletts S, Romao J, Inabu Y, He Z, Haines D, Sugino T, Guan L, Steele M., ASAS-CSAS Annual Meeting, 2018, Without Invitation, English
12. Effect of delayed colostrum feeding on plasma concentrations of glucagon-like peptide 1 and 2 in calves, Inabu Y, Fischer A, Sugino T, Oba M, Guan L L, Steele M A., ADSA Annual Meeting, 2017, Without Invitation, English
13. Effect of lactose inclusion in calf starters on rumen fermentation of weaned calves, Saegusa A, Inouchi K, Ueno M, Inabu Y, Koike S, Sugino T, Oba M., ASAS-ADSA-CSAS-WSASAS Joint Annual Meeting, 2016, Without Invitation, English

External Funds

Acceptance Results of Competitive Funds

1. 2024
2. 2024, 2027
3. 2023
4. 2020, 2022
5. 2019, 2019