SEIZI HAMA

Last Updated :2025/06/14

Affiliations, Positions
Center for Brain, Mind and KANSEI Sciences Research, Associate Professor (Special Appointment)
E-mail
shamahiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Hiroshima University

Research Fields

  • Medicine,dentistry, and pharmacy;Clinical surgery;Neurosurgery
  • Complex systems;Biomedical engineering;Rehabilitation science / Welfare engineering

Affiliated Academic Societies

Research Activities

Academic Papers

  1. Transformation of rat glioma cells with the M-CSF gene inhibits tumorigenesis in vivo, Journal of Neuro-Oncology, 40(3), 197-204, 199812
    Link to Paper Search Results by DOI
  2. Parasellar chronic inflammatory disease presenting Tolosa-Hunt syndrome, hypopituitarism and diabetes insipidus: a case report, Endocrine Journal, 43(5), 503-510, 199610
    Link to Paper Search Results by DOI
  3. Symptomatic Rathke's cleft cyst coexisting with central diabetes insipidus and hypophysitis: case report, Endocrine Journal, 46(1), 187-192, 1999
    Link to Paper Search Results by DOI
  4. Peritumoral brain edema associated with meningioma: influence of vascular endothelial growth factor expression and vascular blood supply, Cancer, 85(4), 936-944, 20001119
    Link to Paper Search Results by DOI
  5. Size-adjustable titanium plate for reconstruction of the sella turcica. Technical note, Journal of Neurosurgery, 91(6), 1055-1057, 199912
    Link to Paper Search Results by DOI
  6. ★, Adenovirus-mediated p16 gene transfer prevents drug-induced cell death through G1 arrest in human glioma cells, International Journal of Cancer, 77(1), 47-54, 19980703
    Link to Paper Search Results by DOI
  7. Genetic immunotherapy by intrapleural, intraperitoneal and subcutaneous injection of IL-2 gene-modified Lewis lung carcinoma cells, International Journal of Cancer, 73(6), 844-849, 19971210
    Link to Paper Search Results by DOI
  8. Transformation of human glioma cell lines with the p16 gene inhibits cell proliferation, ANTICANCER RESEARCH, 17(3C), 1933-1938, 1997
  9. High concentrations of recombinant adenovirus expressing p16 gene induces apoptosis in lung cancer cell lines, ANTICANCER RESEARCH, 18(6A), 4275-4282, 1998
  10. Overcoming multi-drug resistance using an intracellular anti-MDR1 sFv., International Journal of Cancer, 92(1), 115-122, 20010401
  11. Adenovirus-mediated p16 gene transfer changes the sensitivity to taxanes and Vinca alkaloids of human ovarian cancer cells, ANTICANCER RESEARCH, 21(4A), 2537-2545, 2001
  12. Preparation of purified, sterilized, and stable adenovirus vectors using albumin, Journal of Virological Methods, 103(2), 191-199, 20020306
    Link to Paper Search Results by DOI
  13. Absence of mutations in the NBS1 gene in B-cell malignant lymphoma patients, ANTICANCER RESEARCH, 20(3B), 1897-1900, 2000
  14. Recurrence of meningiomas, Cancer, 89(5), 1102-1110, 20001113
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  15. ★, Changes in the epithelium of Rathke cleft cyst associated with inflammation, Journal of Neurosurgery, 96(2), 209-216, 20010925
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  16. Cognitive screening test for rehabilitation using spatiotemporal data extracted from a digital trail making test part-A, HELIYON, 10(13), 20240715
    Link to Paper Search Results by DOI
  17. Vertical dynamic visual acuity is significantly lower than horizontal dynamic visual acuity, SCIENTIFIC REPORTS, 13(1), 20231128
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  18. Motor-cognitive functions required for driving in post-stroke individuals identified via machine-learning analysis, Journal of NeuroEngineering and Rehabilitation, 20(1), 139, 20231018
  19. Artificially-reconstructed brain images with stroke lesions from non-imaging data: modeling in categorized patients based on lesion occurrence and sparsity, Scientific Reports, 12, 10116, 20220616
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  20. Projection of Damaged Visual and Language Regions on Low Trail Making Test Part-B Performance in Stroke Patients, Frontiers in Neurology, 13, 853942, 20220602
  21. Increased cerebrovascular reactivity in selected brain regions after extracranial-intracranial bypass improves the speed and accuracy of visual cancellation in patients with severe steno-occlusive disease: a preliminary study, Neurosurgical Review, 45(3), 2257-2268, 20220130
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  22. Lesions in the right Rolandic operculum are associated with self-rating affective and apathetic depressive symptoms for post-stroke patients, Scientific Reports, 10(1), 20264, 20201120
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  23. Relationships between motor and cognitive functions and subsequent post-stroke mood disorders revealed by machine learning analysis, Scientific Reports, 10(1), 19571, 20201111
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  24. Cerebrospinal fluid ctDNA and metabolites are informative biomarkers for the evaluation of CNS germ cell tumors, Scientific Reports, 10(1), 14326, 20200831
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  25. The right hemisphere is important for driving-related cognitive function after stroke, Neurosurgical Review, 44(2), 977-985, 20200311
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  26. Prognostic importance of temozolomide-induced neutropenia in glioblastoma, IDH-wildtype patients, Neurosurgical Review, 41(2), 621-628, 20170909
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  27. High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas, World Neurosurgery, 105, 282-288, 20170824
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  28. Predicting ischemic stroke after carotid artery stenting based on proximal calcification and the jellyfish sign, Journal of Neurosurgery, 128(5), 1280-1288, 20170707
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  29. Neuroanatomic pathways associated with monoaminergic dysregulation after stroke, International Journal of Geriatric Psychiatry, 32(6), 633-642, 20170511
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  30. Effect of Gonadotropin and Adrenocorticotropic Hormone Secretion on Invasiveness of Clinically Nonfunctioning Pituitary Adenomas: A Cell Culture Study, World Neurosurgery, 96, 578-584, 20160904
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  31. p16 Gene Transfer Induces Centrosome Amplification and Abnormal Nucleation Associated with Survivin Downregulation in Glioma Cells, Pathobiology, 82(1), 1-8, 20150228
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  32. Effect of post-trochanteric groove support on stance control associated with the pelvic-lumbar system: A preliminary study, Prosthetics and Orthotics International, 39(5), 405-413, 20140612
    Link to Paper Search Results by DOI
  33. Neuroanatomic pathway associated with attentional deficits after stroke, Brain Research, 1544, 25-32, 20131207
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  34. Neuroanatomic pathways associated with poststroke affective and apathetic depression, The American Journal of Geriatric Psychiatry, 21(9), 840-847, 20130206
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  35. Carotid arterial intraplaque hemorrhage and calcification influences cerebral hemodynamics, Neurosurgical Review, 36(3), 421-427, 20121214
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  36. Masked hyperprolactinemia: tumor-derived factors inhibiting prolactin secretion caused by pituitary-stalk damage, Journal of Clinical Neuroscience, 18(12), 1651-1655, 20111019
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  37. Post-operative hyponatremia in patients with pituitary adenoma: post-operative management with a uniform treatment protocol, Endocrine Journal, 58(5), 373-379, 20110405
    Link to Paper Search Results by DOI
  38. Post-stroke depression and apathy: Interactions between functional recovery, lesion location, and emotional response, Psychogeriatrics, 11(1), 68-76, 20110330
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  39. Vulnerable carotid arterial plaque causing repeated ischemic stroke can be detected with B-mode ultrasonography as a mobile component: Jellyfish sign, Neurosurgical Review, 33(4), 419-430, 20100619
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  40. The combination of low cytoplasmic and high nuclear expression of p27 predicts a better prognosis in high-grade astrocytoma, Anticancer Research, 29(2), 597-603, 20090201
  41. 'Insistence on recovery' as a positive prognostic factor in Japanese stroke patients, Psychiatry and Clinical Neurosciences, 62(4), 386-395, 20080731
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  42. Centrosome amplification induced by survivin suppression enhances both chromosome instability and radiosensitivity in glioma cells, British Journal of Cancer, 98(2), 345-355, 20080115
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  43. Sitting balance as an early predictor of functional improvement in association with depressive symptoms in stroke patients, Psychiatry and Clinical Neurosciences, 61(5), 543-551, 20070914
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  44. Depression or apathy and functional recovery after stroke, International Journal of Geriatric Psychiatry, 22(10), 1046-1051, 20070814
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  45. Retinoblastoma protein prevents staurosporine-induced cell death in a retinoblastoma-defective human glioma cell line, Pathobiology, 74(1), 22-31, 20070521
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  46. Geminin: a good prognostic factor in high-grade astrocytic brain tumors, Cancer, 109(5), 949-956, 20070129
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  47. Survivin subcellular localization in high-grade astrocytomas: simultaneous expression in both nucleus and cytoplasm is negative prognostic marker, Journal of Neuro-Oncology, 82(2), 193-198, 20061207
    Link to Paper Search Results by DOI
  48. Post-stroke affective or apathetic depression and lesion location: left frontal lobe and bilateral basal ganglia, European Archives of Psychiatry and Clinical Neuroscience, 257(3), 149-152, 20061125
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  49. Cytoplasmic, but not nuclear, p16 expression may signal poor prognosis in high-grade astrocytomas, Journal of Neuro-Oncology, 77(3), 273-277, 20060414
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  50. Prognosis of cerebellar glioblastomas: correlation between prognosis and immunoreactivity for epidermal growth factor receptor compared with supratentorial glioblastomas, ANTICANCER RESEARCH, 26(2B), 1351-1357, 20060301
  51. Monoallelic BUB1B mutations and defective mitotic-spindle checkpoint in seven families with premature chromatid separation (PCS) syndrome, American Journal of Medical Genetics - Part A, 140(4), 358-367, 20060112
    Link to Paper Search Results by DOI
  52. Detection and differentiation of lactate and lipids by single-voxel proton MR spectroscopy, Neurosurgical Review, 28(4), 267-277, 20050818
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  53. Malnutrition and nonthyroidal illness syndrome after stroke, Metabolism, 54(6), 699-704, 20050521
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  54. ★, p16 Gene transfer increases cell killing with abnormal nucleation after ionising radiation in glioma cells, British Journal of Cancer, 89(9), 1802-1811, 20031028
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  55. Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line, Cancer Chemotherapy and Pharmacology, 51(4), 271-283, 20030320
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  56. Expression of survivin in astrocytic tumors: correlation with malignant grade and prognosis, Cancer, 97(4), 1077-1083, 20030203
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  57. Growth hormone receptor expression in brain tumors, Hiroshima Journal of Medical Sciences, 61(1), 1-6, 201203
  58. Apparent diffusion coefficient of human brain tumors at MR imaging, Radiology, 235(3), 985-991, 200506
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  59. Relationship between intratumoral hemorrhage and overexpression of vascular endothelial growth factor (VEGF) in pituitary adenoma, Hiroshima Journal of Medical Sciences, 53(2), 23-27, 200406
  60. Supra-diaphragmatic pituitary adenoma removed through the trans-tuberculum sellae approach. Case report., Neurologia medico-chirurgica, 52(2), 91-95, 2012

Invited Lecture, Oral Presentation, Poster Presentation

  1. Cognitive screening test for rehabilitation using spatiotemporal data extracted from a digital trail making test part-A, Seiji Hama, Akiko Yanagawa, 2024/11/03, Without Invitation, Japanese, Japanese Association of Rehabilitation Medicine