SETSU KATO

Last Updated :2024/06/04

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
E-mail
setsukatohiroshima-u.ac.jp
Self-introduction
How do microbial cells maintain cellular homeostasis for proliferation? Which kind of processes do they go through when they die? We aim to clarify the boundary of life and death and find the principles of life using the single cell quantitative method. These findings will help us to create useful host cells for bioprocess.

Basic Information

Major Professional Backgrounds

  • 2022/10/01, Hiroshima University, Graduate School of Integrated Sciences for Life, Associate Professor
  • 2017/12/01, 2019/03/31, Hiroshima University, Graduate School of Advanced Sciences of Matter, Assistant Professor
  • 2019/04/01, 2022/09/30, Hiroshima University, Graduate School of Integrated Sciences for Life, Assistant Professor

Educational Backgrounds

  • The University of Tokyo, Japan, 2007/04, 2010/03

Academic Degrees

  • The University of Tokyo
  • The University of Tokyo

Educational Activity

  • [Bachelor Degree Program] School of Engineering : Cluster 3(Applied Chemistry, Biotechnology and Chemical Engineering) : Program of Biotechnology
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology

Research Fields

  • Agricultural sciences;Agricultural chemistry;Applied microbiology
  • Biology;Biological Science;Molecular biology

Affiliated Academic Societies

  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • The Molecular Biology Society of Japan
  • Society of Genome Microbiology, Japan
  • The Society of Biotechnology, Japan

Educational Activity

Course in Charge

  1. 2024, Undergraduate Education, 2Term, Biochemistry I
  2. 2024, Undergraduate Education, Second Semester, Basic Experiments in Chemistry
  3. 2024, Undergraduate Education, 4Term, Basic life science
  4. 2024, Undergraduate Education, First Semester, Training of Biotechnology I
  5. 2024, Undergraduate Education, Year, Graduation Thesis
  6. 2024, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
  7. 2024, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
  8. 2024, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
  9. 2024, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
  10. 2024, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B
  11. 2024, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biotechnology

Research Activities

Academic Papers

  1. Enhancing acetone production from H2 and CO2 using supplemental electron acceptors in an engineered Moorella thermoacetica., Journal of bioscience and bioengineering, 136(1), 2023
  2. A targeted liquid cultivation method for previously uncultured non-colony forming microbes., Frontiers in microbiology, 14, 2023
  3. Reversible Hydrogenase Activity Confers Flexibility to Balance Intracellular Redox in Moorella thermoacetica, FRONTIERS IN MICROBIOLOGY, 13, 20220512
  4. Single-Cell Time-Lapse Observation Reveals Cell Shrinkage upon Cell Death in Batch Culture of Saccharomyces cerevisiae., mBio, 12(6), 2021
  5. Autotrophic growth and ethanol production enabled by diverting acetate flux in the metabolically engineered Moorella thermoacetica., Journal of bioscience and bioengineering, 132(6), 2021
  6. Metabolic engineering of Moorella thermoacetica for thermophilic bioconversion of gaseous substrates to a volatile chemical, AMB EXPRESS, 11(1), 20210423
  7. Direct detection of mRNA expression in microbial cells by fluorescence in situ hybridization using RNase H-assisted rolling circle amplification, SCIENTIFIC REPORTS, 10(1), 20200615
  8. The mechanosensitive channel YbdG from Escherichia coli has a role in adaptation to osmotic up-shock., The Journal of biological chemistry, 294(33), 2019
  9. Ethanol yield and sugar usability in thermophilic ethanol production from lignocellulose hydrolysate by genetically engineered Moorella thermoacetica, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 129(2), 160-164, 202002
  10. Spatial self-organization resolves conflicts between individuality and collective migration, NATURE COMMUNICATIONS, 9, 2018
  11. Cell size homeostasis in bacteria, Experimental Medicine, 36(13), 2193-2197, 2018
  12. Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators., eLife, 6, 2017
  13. A constant size extension drives bacterial cell size homeostasis., Cell, 159(6), 2014
  14. Purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of AdpA, the central transcription factor in the A-factor regulatory cascade in the filamentous bacterium Streptomyces griseus, in complex with a duplex DNA., Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 8), 2012
  15. Conditionally positive effect of the TetR-family transcriptional regulator AtrA on streptomycin production by Streptomyces griseus., Microbiology (Reading, England), 154(Pt 3), 2008
  16. Control of the Streptomyces Subtilisin inhibitor gene by AdpA in the A-factor regulatory cascade in Streptomyces griseus., Journal of bacteriology, 188(17), 2006
  17. The Streptomyces subtilisin inhibitor (SSI) gene in Streptomyces coelicolor A3(2)., Bioscience, biotechnology, and biochemistry, 69(8), 2005

Invited Lecture, Oral Presentation, Poster Presentation

  1. Growth of abnormally shaped cells in E. coli populations, Setsu Kato, The 45th Annual Meeting of the Molecular Biology Society of Japan, 2022/12/01, With Invitation, Japanese, Molecular Biology Society of Japan, Japan, Chiba
  2. Single-cell observation to understand the process of cell death, Setsu Kato, The 35th Japanese Society of Microbial Ecology (JSME) Annual conference, 2022/11/03, With Invitation, English, Japanese Society of Microbial Ecology (JSME), Hokkaido, Japan
  3. Spatial and temporal control of bacterial culture environments in microfluidic devices, Setsu Kato, The 2022 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry, 2022/03/16, With Invitation, Japanese, The Japan Society for Bioscience, Biotechnology, and Agrochemistry, online
  4. Life and death of Escherichia coli cells in batch culture, Setsu Kato, The 44th Annual Meeting of the Molecular Biology Society of Japan, 2021/12/02, With Invitation, English, The Molecular Biology Society of Japan, online
  5. Microbial cell death by nutrient starvation, Setsu Kato, The 2021 Annual Meeting of the Japan Society for Bioscience, Biotechnology, and Agrochemistry, 2021/03/20, With Invitation, Japanese, The Japan Society for Bioscience, Biotechnology, and Agrochemistry, online
  6. Single cell analysis to understand the behavior of bacterial cells, Setsu Kato, 2018 JSME annual meeting and 10th ASME, 2018/07/12, With Invitation, English, JSME, Okinawa, Japan

External Funds

Acceptance Results of Competitive Funds

  1. Fusion Oriented REsearch for disruptive Science and Technology, 2022, 2024
  2. KAKENHI(Grant-in-Aid for Research Activity Start-up), 2018, 2019
  3. KAKENHI(Grant-in-Aid for Scientific Research (B)), 2019, 2022
  4. KAKENHI(Grant-in-Aid for Scientific Research on Innovative Areas), 2020, 2021