RYOTA NOMURA
Last Updated :2025/06/16
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences, Professor
- Web Site
- E-mail
- rnomura
hiroshima-u.ac.jp
- Self-introduction
- Specialty: Pediatric dentistry, Oral microbiology
Basic Information
Major Professional Backgrounds
- 2022/02/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Professor
Educational Backgrounds
- Osaka University, Japan, 2002/04, 2006/03
- Osaka University, School of Dentistry, Japan, 1996/04, 2002/03
Academic Degrees
Educational Activity
- [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
- [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences : Program of Dental Sciences
Research Fields
- Medicine,dentistry, and pharmacy;Dentistry;Orthodontics / Pediatric dentistry
Research Keywords
Affiliated Academic Societies
- Pediatric Dentistry, 2002/04, 2002/04
Educational Activity
Course in Charge
- 2025, Liberal Arts Education Program1, 2Term, General Health and Oral Sciences I
- 2025, Undergraduate Education, 2Term, Pediatrics
- 2025, Undergraduate Education, 2Term, Topics in Dental Research II
- 2025, Undergraduate Education, 4Term, Special Subject
- 2025, Undergraduate Education, 1Term, Pediatric Dentistry I
- 2025, Undergraduate Education, 2Term, Pediatric Dentistry II
- 2025, Undergraduate Education, First Semester, Dental Research Practices I
- 2025, Undergraduate Education, 3Term, Basic Practice of Pediatric Dentistry I
- 2025, Undergraduate Education, 4Term, Basic Practice of Pediatric Dentistry II
- 2025, Undergraduate Education, Second Semester, Dental Research Practices II
- 2025, Undergraduate Education, 2Term, Advanced Course in Growth and Development of Occlusion
- 2025, Undergraduate Education, First Semester, Dental Research Practices III
- 2025, Undergraduate Education, Year, Clinical Practice (Pedodontics)
- 2025, Undergraduate Education, 2Term, Pediatric Dentistry
- 2025, Undergraduate Education, 2Term, Pediatrics
- 2025, Undergraduate Education, First Semester, Overview of Oral Engineering
- 2025, Undergraduate Education, 2Term, Pediatric Dentistry
- 2025, Undergraduate Education, 3Term, Practice of Pediatric Dentistry
- 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Pediatric Dentistry
- 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Pediatric Dentistry
- 2025, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Pediatric Dentistry
- 2025, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Pediatric Dentistry
- 2025, Graduate Education (Master's Program) , First Semester, Lecture on Oral Health Sciences
- 2025, Graduate Education (Doctoral Program) , First Semester, Training Course for Specialist of Pediatric Dentistry
- 2025, Graduate Education (Doctoral Program) , Second Semester, Training Course for Specialist of Pediatric Dentistry
Research Activities
Academic Papers
- Clinical and genetic analysis of oral and nasal staphylococcus aureus isolates in dental patients, SCIENTIFIC REPORTS, 15(1), 20250416
- A Systematic Review of the Oral Health Status of Hemophilic Patients, CHILDREN-BASEL, 12(4), 20250410
- Effect of Helicobacter pylori on enamel and dentin development - an in vitro study in mice, JOURNAL OF ORAL MICROBIOLOGY, 17(1), 20251231
- A Case of Severe Early Childhood Caries Occurring in a Childhood Cancer Patient, CHILDREN-BASEL, 12(3), 20250220
- A Second Residual Tooth Occurring from One Tooth, DIAGNOSTICS, 15(6), 20250314
- Long-Term Follow-Up of a Patient with Ankylosis of a Primary Incisor Caused by Trauma: A Case Report, REPORTS, 8(1), 20250226
- Relationship between childhood caries and social background: Regarding the novel emerged correlation between induced abortion and dental caries, PEDIATRIC DENTAL JOURNAL, 35(1), 202504
- Case Study of a Broken Instrument in a Primary Tooth and Literature Review, CHILDREN-BASEL, 12(2), 202502
- A Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage, CHILDREN-BASEL, 12(1), 202501
- RadImageNet and ImageNet as Datasets for Transfer Learning in the Assessment of Dental Radiographs: A Comparative Study, JOURNAL OF IMAGING INFORMATICS IN MEDICINE, 38(1), 534-544, 202502
- Usefulness of Generative Artificial Intelligence (AI) Tools in Pediatric Dentistry, DIAGNOSTICS, 14(24), 202412
- Role of fimbriae variations in Porphyromonas gulae biofilm formation, JOURNAL OF ORAL BIOSCIENCES, 66(4), 28-33, 202412
- Eruption Disturbance in Children Receiving Bisphosphonates: Two Case Reports, PHARMACEUTICALS, 17(11), 202411
- Relationship Between the Presence of Red Complex Species and the Distribution of Other Oral Bacteria, Including Major Periodontal Pathogens in Older Japanese Individuals, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(22), 202411
- Is Oral Streptococcus mutans with Collagen-Binding Protein a Risk Factor for Intracranial Aneurysm Rupture or Formation?, CEREBROVASCULAR DISEASES, 53(6), 722-728, 202501
- Current knowledge regarding infective endocarditis prevention among dentists affiliated with the Japanese Society of Pediatric Dentistry, PEDIATRIC DENTAL JOURNAL, 34(3), 129-135, 202412
- Unique oral finding in a patient with Pitt-Hopkins Syndrome, PEDIATRIC DENTAL JOURNAL, 34(3), 201-205, 202412
- Eruption disturbance in first molar and primary second molar caused by multiple compound odontomas: a case report, JOURNAL OF CLINICAL PEDIATRIC DENTISTRY, 48(6), 236-242, 2024
- Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses, BMC ORAL HEALTH, 24(1), 20240911
- A Narrative Review of the Association between Dental Abnormalities and Chemotherapy, JOURNAL OF CLINICAL MEDICINE, 13(16), 202408
- Inhibitory Effects of Surface Pre-Reacted Glass Ionomer Filler Eluate on Streptococcus mutans in the Presence of Sucrose, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(17), 202409
- Contribution of collagen-binding protein Cnm of Streptococcus mutans to induced IgA nephropathy-like nephritis in rats, COMMUNICATIONS BIOLOGY, 7(1), 20240914
- Role of N1-Domain, Linker, N2-Domain, and Latch in the Binding Activity and Stability of the Collagen-Binding Domain for the Collagen-Binding Protein Cbm from Streptococcus mutans, PHYSCHEM, 4(2), 120-130, 202406
- High-performance silica-containing professional mechanical tooth-cleaning paste that effectively adsorbs pigments, PEDIATRIC DENTAL JOURNAL, 34(2), 62-69, 202408
- Effects of Oleanolic Acid Derived from Wine Pomace on Periodontopathic Bacterial Growth in Healthy Individuals: A Randomized Placebo-Controlled Study, DENTISTRY JOURNAL, 12(5), 202405
- Dental Abnormalities in Pediatric Patients Receiving Chemotherapy, JOURNAL OF CLINICAL MEDICINE, 13(10), 202405
- Fusion of a tooth with a supernumerary tooth: A case report and literature review of 35 cases, Children, 11(1), 6-6, 2023
- Dens invaginatus of fourteen teeth in a pediatric patient:, Pediatric Dental Journal, 33(3), 240-245, 2023
- Eruption disturbance in first molar and primary second molar caused by multiple compound odontomas: A Case report, Journal of Clinical Pediatric Dentistry, 2023
- Age estimation using post-mortem computed tomography and fetal dental radiographic findings in an early to mid-pregnancy fetus: A case report, Legal Medicine, 62, 102232-102232, 2023
- Oral and rectal colonization of methicillin-resistant Staphylococcus aureus in long-term care facility residents and their association with clinical status, Microbiology and Immunology, 2023
- Porphyromonas gingivalis infection in the oral cavity is associated with elevated galactose-deficient IgA1 and increased nephritis severity in IgA nephropathy, Clinical and Experimental Nephrology, 2023
- Harboring Cnm-expressing Streptococcus mutans in the oral cavity relates to both deep and lobar cerebral microbleeds, European Journal of Neurology, 30(11), 3487-3496, 2023
- Investigation of periodontal disease development and Porphyromonas gulae FimA genotype distribution in small dogs, SCIENTIFIC REPORTS, 14(1), 20240304
- Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity, JOURNAL OF ORAL MICROBIOLOGY, 16(1), 2023
- Evaluation of Periodontal Status and Oral Health Habits with Continual Dental Support for Young Patients with Hemophilia, APPLIED SCIENCES-BASEL, 14(4), 2023
- Inhibitory Effects of Shikonin Dispersion, an Extract of Lithospermum erythrorhizon Encapsulated in β-1,3-1,6 Glucan, on Streptococcus mutans and Non-Mutans Streptococci, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25(2), 202401
- Effects of mouthwash on periodontal pathogens and glycemic control in patients with type 2 diabetes mellitus, SCIENTIFIC REPORTS, 14(1), 20240202
- Dens invaginatus of fourteen teeth in a pediatric patient, PEDIATRIC DENTAL JOURNAL, 33(3), 240-245, 202312
- Structure, Stability and Binding Properties of Collagen-Binding Domains from Streptococcus mutans, CHEMISTRY-SWITZERLAND, 5(3), 1911-1920, 202309
- Inhibitory Effect of Adsorption of Streptococcus mutans onto Scallop-Derived Hydroxyapatite, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(14), 202307
- Application of the salivary multi test in children with severe congenital neutropenia: A case report, PEDIATRIC DENTAL JOURNAL, 33(2), 152-158, 202308
- Multiple-Ion Releasing Bioactive Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler: Innovative Technology for Dental Treatment and Care, JOURNAL OF FUNCTIONAL BIOMATERIALS, 14(4), 202304
- Distribution of periodontopathic bacterial species between saliva and tonsils, ODONTOLOGY, 111(3), 719-727, 202307
- Simultaneous Presence of Campylobacter rectus and Cnm-Positive Streptococcus mutans in the Oral Cavity Is Associated with Renal Dysfunction in IgA Nephropathy Patients: 5-Year Follow-Up Analysis, NEPHRON, 147(3-4), 134-143, 202304
- Character ization of protease from animal periodontal pathogen Porphyromonas gulae, JAPANESE JOURNAL OF VETERINARY RESEARCH, 70(3-4), 79-90, 202211
- Development of Rat Caries-Induced Pulpitis Model for Vital Pulp Therapy, JOURNAL OF DENTAL RESEARCH, 102(5), 574-582, 202305
- Five-Year Follow-Up of a Child with Non-Syndromic Oligodontia from before the Primary Dentition Stage: A Case Report, CHILDREN-BASEL, 10(4), 202304
- cnm-positive Streptococcus mutans is associated with galactose-deficient IgA in patients with IgA nephropathy, PLOS ONE, 18(3), 20230302
- A Third Supernumerary Tooth Occurring in the Same Region: A Case Report, DENTISTRY JOURNAL, 11(2), 202302
- Possible association of fimA genotype of Porphyromonas gulae with the severity of periodontal disease and the number of permanent teeth in dogs, FRONTIERS IN VETERINARY SCIENCE, 10, 20230206
- Detection of Helicobacter pylori from Extracted Teeth of a Patient with Idiopathic Thrombocytopenic Purpura, MICROORGANISMS, 10(11), 202211
- Analysis of the feasibility of using deep learning for multiclass classification of dental anomalies on panoramic radiographs, DENTAL MATERIALS JOURNAL, 41(6), 889-895, 202212
- Dental radiographic information of term newborn babies within the first month: Analyzing five radiographic cases along with physical attributes in Japan, LEGAL MEDICINE, 60, 202302
- Clinical characteristics of children and guardians possessing CBP-positive Streptococcus mutans strains: a cross-sectional study, SCIENTIFIC REPORTS, 12(1), 20221020
- Green tea catechins inhibit Porphyromonas gulae LPS-induced inflammatory responses in human gingival epithelial cells, JOURNAL OF ORAL BIOSCIENCES, 64(3), 352-358, 202209
- Characterization of the unique oral microbiome of children with Down syndrome, SCIENTIFIC REPORTS, 12(1), 20220819
Invited Lecture, Oral Presentation, Poster Presentation
- Three-year survey of dental caries conditions in Cambodian public primary school, Asao Y., Iwamoto Y., Nakano M., Akitomo T., Usuda M., Kametani M., Kusaka S., Tachikake M., Mitsuhata C., Nomura R, Asao Y., Iwamoto Y., Nakano M., Akitomo T., Usuda M., Kametani M., Kusaka S., Tachikake M., Mitsuhata C., Nomura R, Korean Academy of Pediatric Dentistry 2023 Conference, 2023/05/30, Without Invitation, English
- Interaction of essential oils in Citrus unshiu to cause inhibition of Streptococcus mutans bacterial growth, Okuda M., Ohata J., Matayoshi S., Nomura R., Nakano K., Okuda M., Ohata J., Matayoshi S., Nomura R., Nakano K., Korean Academy of Pediatric Dentistry 2023 Conference, 2023/05/30, Without Invitation, English
- Contributions of Streptococcus mutans to dental caries and infective endocarditis, Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., Korean Academy of Pediatric Dentistry 2023 Conference, 2023/05/30, Without Invitation, English
- IgA adherence to Streptococcus mutans Cnm for IgA nephropathy onset, Matsuoka D., Suehara K., Naka S., Misaki T., Nagasawa Y., Ito S., Nomura R., Nakano K, Matsuoka D., Suehara K., Naka S., Misaki T., Nagasawa Y., Ito S., Nomura R., Nakano K, 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Effects of mouthwash on oral and systemic health of diabetic, Tojo F., Matayoshi S., Nomura R., Nakano K, Tojo F., Matayoshi S., Nomura R., Nakano K, 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Periodontal disease in dogs correlates with FimA of Porphyromonas gulae, Suehiro Y., Matayoshi S., Yasuda J., Yasuda H., Gongora E., Matsumoto-Nakano M., Nomura R., Nakano K, Suehiro Y., Matayoshi S., Yasuda J., Yasuda H., Gongora E., Matsumoto-Nakano M., Nomura R., Nakano K, 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Association of Helicobacter pylori in oral cavity and Parkinson's disease, Kadota T., Matsuoka Y., Hamada M., Ogaya Y., Nomura R., Nakano N., Kadota T., Matsuoka Y., Hamada M., Ogaya Y., Nomura R., Nakano N., 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Possible unique oral microbiome characteristics in children harboring Helicobacter pylori in the oral cavity, Ogaya Y., Kadota Y., Nomura R., Nakano K, Ogaya Y., Kadota Y., Nomura R., Nakano K, 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Serum agglutinating ability of Streptococcus mutans killed by antibiotic, Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., 101st General Session & Exhibition of the IADR (Bogotá, Colombia), 2023/07/30, Without Invitation, English
- Effects of continuous dental support on periodontal status and oral health activities of hemophilic patients, Kametani M., Akitomo T., Niizato N., Usuda M., Kusaka S., Asao Y., Nakano M., Iwamoto Y., Tachikake M., Mitsuhata C., Nomura R, Kametani M., Akitomo T., Niizato N., Usuda M., Kusaka S., Asao Y., Nakano M., Iwamoto Y., Tachikake M., Mitsuhata C., Nomura R, 29th IAPD Congress (Maastricht, Netherland), 2023/07/20, Without Invitation, English
- Inhibitory effects of S-PRG filler eluate on acid tolerance of Streptococcus mutans, Usuda M., Kametani M., Akitomo T., Nakano M., Suehiro Y., Matayoshi S., Mitsuhata C., Nakano K., Nomura R., Usuda M., Kametani M., Akitomo T., Nakano M., Suehiro Y., Matayoshi S., Mitsuhata C., Nakano K., Nomura R., 29th IAPD Congress (Maastricht, Netherland), 2023/07/20, Without Invitation, English
- Effect of professional mechanical tooth cleaning paste with high-performance silica on stain deposition, Akitomo T., Kusaka S., Usuda M., Kametani M., Hirose M., Takane S., Mitsuhata C., Nakano K., Nomura R, Akitomo T., Kusaka S., Usuda M., Kametani M., Hirose M., Takane S., Mitsuhata C., Nakano K., Nomura R, 29th IAPD Congress (Maastricht, Netherland), 2023/07/20, Without Invitation, English
- Pathogenicity of collagen-binding protein in Streptococcus mutans, Matsuoka D., Naka S., Goto K., Nomura R., Nakano K., Matsumoto-Nakano M, Matsuoka D., Naka S., Goto K., Nomura R., Nakano K., Matsumoto-Nakano M, 29th IAPD Congress (Maastricht, Netherland), 2023/07/20, Without Invitation, English
- Cariology and systemic disorder collagen-binding properties of killed Streptococcus mutans strains, Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., 29th IAPD Congress (Maastricht, Netherland), 2023/07/01, Without Invitation, English
- Association of Helicobacter pylori in the oral cavity and dental caries with lifestyle-related disease, Kadota T., Hamada M., Nomura R., Nakano K, Kadota T., Hamada M., Nomura R., Nakano K, The 70th ORCA congress (Egmond aan zee, Netherland), 2023/07/01, Without Invitation, English
- Absorption effect of high-performance silica on food-derived dyes, Akitomo T., Kusaka S., Usuda M., Kametani M., Ogawa M., Kaneki A., Mitsuhata C. Nomura R, Akitomo T., Kusaka S., Usuda M., Kametani M., Ogawa M., Kaneki A., Mitsuhata C. Nomura R, 32nd Annual Conference of the Taiwan Academy of Pediatric Dentistry (Kaohsiung, Taiwan), 2023/06/30, Without Invitation, English
- The changes on dental caries status of first molars among primary school children in Cambodia, Asao Y., Iwamoto Y., Nishimura T., Nakano M., Tachikake M., Mitsuhata C., Nomura R, Asao Y., Iwamoto Y., Nishimura T., Nakano M., Tachikake M., Mitsuhata C., Nomura R, 32nd Annual Conference of the Taiwan Academy of Pediatric Dentistry (Kaohsiung, Taiwan), 2023/06/30, Without Invitation, English
- Evaluation of killed Streptococcus mutans strains by fluorescence microscopy, Mikasa Y., Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., Mikasa Y., Suehiro Y., Matayoshi S., Otsugu M., Nomura R., Nakano K., 32nd Annual Conference of the Taiwan Academy of Pediatric Dentistry (Kaohsiung, Taiwan), 2023/06/30, Without Invitation, English
- Possible mediation of tonsils to IgA nephropathy caused by cnm-positive Streptococcus mutans, a major pathogen of dental caries, Misaki T., Naka S., Nagasawa Y., Matsuoka D., Matayoshi S., Ito S., Nomura R., Matsumoto-Nakano M., Nakano K, Misaki T., Naka S., Nagasawa Y., Matsuoka D., Matayoshi S., Ito S., Nomura R., Matsumoto-Nakano M., Nakano K, 17th International symposium on IgA nephropathy (IIgAN) (Tokyo), 2023/12/10, Without Invitation, English
- Relation between Porphyromonas gingivalis infection in oral cavity and elevated galactose-deficient IgA1 in IgA nephropathy, Ito S., Misaki T., Nagasawa Y., Nomura R., Naka S., Fukunaga A., Matsuoka D., Matayoshi S., Matsumoto-Nakano., Kazuhiko Nakano K, Ito S., Misaki T., Nagasawa Y., Nomura R., Naka S., Fukunaga A., Matsuoka D., Matayoshi S., Matsumoto-Nakano., Kazuhiko Nakano K, 17th International symposium on IgA nephropathy (IIgAN) (Tokyo), 2023/12/10, Without Invitation, English
- Prevalence of periodontitis-related bacteria in tonsils of IgA nephropathy patients compared with those in habitual tonsilitis patients, Nagasawa Y., Nomura R., Misaki T., Ito S., Naka S., Matsuoka D., Matayoshi S., Matsumoto-Nakano M., Nakano K, Nagasawa Y., Nomura R., Misaki T., Ito S., Naka S., Matsuoka D., Matayoshi S., Matsumoto-Nakano M., Nakano K, 17th International symposium on IgA nephropathy (IIgAN) (Tokyo), 2023/12/10, Without Invitation, English
- cnm-positive Streptococcus mutans, a major pathogen of dental caries may cause IgA nephropathy via tonsils, Misaki T., Naka S., Nagasawa Y., Matsuoka D., Matayoshi S., Ito S., Nomura R., Matsumoto-Nakano M., Nakano K., Misaki T., Naka S., Nagasawa Y., Matsuoka D., Matayoshi S., Ito S., Nomura R., Matsumoto-Nakano M., Nakano K., The Kidney Week 2023 (Philadelphia, USA),, 2023/11/15, Without Invitation, English
- Collagen-binding protein pathogenicity in rat model of IgA nephropathy, Suehara K., Matsuoka D., Naka S., Misaki T., Nagasawa Y., Ito S., Nomura R., Nakano K., Matsumoto-Nakano M, Suehara K., Matsuoka D., Naka S., Misaki T., Nagasawa Y., Ito S., Nomura R., Nakano K., Matsumoto-Nakano M, Japanese Association for Dental Research (JADR) (Sendai), 2023/11/30, Without Invitation, English
- The oral conditions of Cambodian public primary school children before and after the COVID-19 pandemic:, Asao Y., Iwamoto Y., Nishimura T., Kaneki A., Usuda M., Kametani M., Akitomo T., Nakano M., Kondo M., Ogura T., Mitsuhata M., Nomura R., Naito M, Asao Y., Iwamoto Y., Nishimura T., Kaneki A., Usuda M., Kametani M., Akitomo T., Nakano M., Kondo M., Ogura T., Mitsuhata M., Nomura R., Naito M, 15th International Conference of the Asian Academy of Preventive Dentistry (Hong Kong), 2023/11/20, Without Invitation, English
External Funds
Acceptance Results of Competitive Funds
- KAKENHI(Grant-in-Aid for Scientific Research (B)), 2021, 2023
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
- KAKENHI(Grant-in-Aid for Scientific Research (B)), 2021, 2023
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2022, 2024
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2022, 2024
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2021, 2023
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2022, 2024
- KAKENHI(Grant-in-Aid for Scientific Research (C)), 2023, 2025