SOTARO FUJII

Last Updated :2025/06/16

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Assistant Professor
E-mail
sofujihiroshima-u.ac.jp

Basic Information

Academic Degrees

  • Hiroshima University
  • Hiroshima University

Research Fields

  • Agricultural sciences;Agricultural chemistry;Applied microbiology

Research Keywords

  • Extremophiles

Educational Activity

Course in Charge

  1. 2025, Liberal Arts Education Program1, 1Term, Introduction to Applied Biological Sciences toward SDGs
  2. 2025, Liberal Arts Education Program1, 1Term, Introductory Seminar for First-Year Students
  3. 2025, Undergraduate Education, 1Term, Introduction to Applied Biological Sciences
  4. 2025, Undergraduate Education, Intensive, Laboratory Work in General Chemistry
  5. 2025, Undergraduate Education, 4Term, Introduction to Molecular Biochemistry
  6. 2025, Undergraduate Education, Intensive, Introduction to Molecular Biochemistry
  7. 2025, Undergraduate Education, 3Term, Bio-organic Chemistry
  8. 2025, Undergraduate Education, Second Semester, Graduation Thesis I
  9. 2025, Undergraduate Education, First Semester, Graduation Thesis II
  10. 2025, Undergraduate Education, Second Semester, Graduation Thesis III
  11. 2025, Undergraduate Education, 3Term, Genome Science II
  12. 2025, Undergraduate Education, Intensive, Laboratory Work in Molecular Agro-life Science I
  13. 2025, Undergraduate Education, 4Term, Bio-Analytical Science
  14. 2025, Undergraduate Education, 3Term, Reading of Foreign Literature in Molecular Agro-Life Science
  15. 2025, Graduate Education (Master's Program) , 1Term, Exercises in Food andAgriLife Science A
  16. 2025, Graduate Education (Master's Program) , 2Term, Exercises in Food andAgriLife Science A
  17. 2025, Graduate Education (Master's Program) , 3Term, Exercises in Food andAgriLife Science B
  18. 2025, Graduate Education (Master's Program) , 4Term, Exercises in Food andAgriLife Science B
  19. 2025, Graduate Education (Master's Program) , Year, Research for Academic Degree Dissertation in Food andAgriLife Science
  20. 2025, Graduate Education (Master's Program) , 2Term, Applied Molecular Cell Biology I
  21. 2025, Graduate Education (Master's Program) , 4Term, Applied Molecular Cell Biology II

Research Activities

Academic Papers

  1. Cytochromes P460 and c′-β: exploiting a novel fold for multiple functions, JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 30(2), 181-207, 202503
    Link to Paper Search Results by DOI
  2. Thermal tolerance of larvae of seven Chironomus species and up-regulation of heat shock protein-coding genes in Chironomus sulfurosus, LIMNOLOGY, 26(1), 125-133, 202501
    Link to Paper Search Results by DOI
  3. Conformational rigidity of cytochrome c'-a from a thermophile is associated with slow NO binding, BIOPHYSICAL JOURNAL, 123(16), 2594-2603, 20240820
    Link to Paper Search Results by DOI
  4. Membrane contact sites regulate vacuolar fission via sphingolipid metabolism, ELIFE, 12, 20240327
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  5. Isolation and characterization of bacteria from the gut of a mesopelagic copepod Cephalophanes reflugens (Copepoda: Calanoida), JOURNAL OF PLANKTON RESEARCH, 46(1), 48-58, 20240120
    Link to Paper Search Results by DOI
  6. Species-specific Microorganisms in Acid-tolerant Chironomus Larvae Reared in a Neutral pH Range under Laboratory Conditions: Single Dataset Analysis, MICROBES AND ENVIRONMENTS, 38(6), 2023
    Link to Paper Search Results by DOI
  7. Contribution of a surface salt bridge to the protein stability of deep-sea Shewanella benthica cytochrome c', JOURNAL OF STRUCTURAL BIOLOGY, 215(4), 202312
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  8. Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi, IUCrJ, 10(4), 20230701
    Link to Paper Search Results by DOI
  9. A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-beta: Implications for NO sensors, Journal of Biological Chemistry, 299(6), 104742, 20230424
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  10. Lentilactobacillus hilgardii H-50 strongly inhibits lipopolysaccharide-induced inflammatory responses in mouse splenocytes via its specific surface layer proteins, JOURNAL OF APPLIED MICROBIOLOGY, 134(3), 20230301
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  11. Heterologous expression and biochemical comparison of two homologous SoxX proteins of endosymbiotic Candidatus Vesicomyosocius okutanii and free-living Hydrogenovibrio crunogenus from deep-sea environments, PROTEIN EXPRESSION AND PURIFICATION, 200, 202212
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  12. Crystal structure of thermally stable homodimeric cytochrome c '-beta from Thermus thermophilus, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 78, 217-225, 20220527
    Link to Paper Search Results by DOI
  13. ★, High thermal stability and unique trimer formation of cytochrome c' from thermophilic Hydrogenophilus thermoluteolus., Biosci. Biotechnol. Biochem., 77(8), 1677-1681, 2013
  14. Stabilization of mesophilic Allochromatium vinosum cytochrome c through specific mutations modeled by a thermophilic homologue, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 82(2), 304-311, 2018
    Link to Paper Search Results by DOI
  15. Commonly stabilized cytochromes c from deep-sea Shewanella and Pseudomonas, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 82(5), 792-799, 2018
    Link to Paper Search Results by DOI
  16. ★, High stability of apo-cytochrome c' from thermophilic Hydrogenophilus thermoluteolus, Bioscience, Biotechnology, and Biochemistry, 78(7), 1191-1194, 2014
  17. Thermal stability of cytochrome c' from mesophilic Shewanella amazonensis., Biosci. Biotechnol. Biochem., 79(7), 1125-1129, 20150310
  18. Comparative study on stabilization mechanism of monomeric cytochrome c5 from deep-sea piezophilic Shewanella violacea., Biosci. Biotechnol. Biochem., 80(12), 2365-2370, 20160920
  19. Difference in NaCl tolerance of membrane-bound 5'-nucleotidases purified from deep-sea and brackish water Shewanella species., Extremophiles, 21(2), 357-368, 20170321
  20. ★, Structural and functional insights into thermally stable cytochrome c' from a thermophile, Protein Sci., 26, 737-748, 2017
  21. Pyrophosphate hydrolysis in the extremely halophilic archaeon Haloarcula japonica is catalyzed by a single enzyme with a broad ionic strength range., Extremophiles, 21(3), 471-477, 20170217
  22. Pseudomonas aeruginosa cytochrome c551 denaturation by five systematic urea derivatives that differ in the alkyl chain length., Biosci. Biotechnol. Biochem., 81(7), 1274-1278, 20170320
  23. Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure., Extrempphiles, 23(2), 239-248, 20190128
  24. Conferment of CO-Controlled Dimer-Monomer Transition Property to Thermostable Cytochrome c ' by Mutation in the Subunit-Subunit Interface, BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 92(3), 702-709, 201903
    Link to Paper Search Results by DOI
  25. One fold, two functions: cytochrome P460 and cytochrome c '-beta from the methanotroph Methylococcus capsulatus (Bath), CHEMICAL SCIENCE, 10(10), 3031-3041, 20190314
    Link to Paper Search Results by DOI
  26. Response of neutrophilic Shewanella violacea to acid stress: growth rate, organic acid production, and gene expression, EXTREMOPHILES, 23(3), 319-326, 201905
    Link to Paper Search Results by DOI
  27. Differences in biochemical properties of two 5-nucleotidases from deep- and shallow-sea Shewanella species under various harsh conditions, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 83(6), 1085-1093, 20190603
    Link to Paper Search Results by DOI
  28. Expression of two glutamate decarboxylase genes in Lactobacillus brevis during gamma-aminobutyric acid production with date residue extract, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 84(5), 1069-1072, 20200503
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  29. Fermented date residue extract mix containing gamma-aminobutyric acid augments the immune function of mouse splenocytes, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 85(7), 1753-1758, 20210624
    Link to Paper Search Results by DOI
  30. Identification of six CPC-like genes and their differential expression in leaves of tea plant, Camellia sinensis, JOURNAL OF PLANT PHYSIOLOGY, 263, 202108
    Link to Paper Search Results by DOI
  31. ★, Transcriptome analysis of Chironomus sulfurosus larvae living in acidic environments: Insights into molecular mechanisms for acid tolerance, Journal of Insect Physiology, 133, 104288, 20210731
  32. ★, Thermal stability tuning without affecting gas-binding function of Thermochromatium tepidum cytochrome c', BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 85(8), 1846-1852, 20210723
  33. Unexpectedly high thermostability of an NADP-dependent malic enzyme from a psychrophilic bacterium, Shewanella livingstonensis Ac10, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 21, S1389-1723, 20210808

External Funds

Acceptance Results of Competitive Funds

  1. JSPS oversea fellowship, NO-binding affinity and structures in cytochromes c' from extremophiles, 2021/02/01, 2023/01/31