RYUICHI HIROTA
Last Updated :2023/06/01
- Affiliations, Positions
- Graduate School of Integrated Sciences for Life, Associate Professor
- Web Site
- E-mail
- hirota
hiroshima-u.ac.jp
Basic Information
Major Professional Backgrounds
- 2007/03/01, 2017/05/31, Graduate School of Advanced Sciences of Matter, Assistant Professor
- 2013/09/28, 2014/11/28, University of Illinois Urbana-Champaign, Visiting Scholar
- 2017/06/01, 2019/03/31, Graduate School of Advanced Sciences of Matter, Associate Professor
- 2019/04/01, Graduate School of Integrated Sciences for Life, Associate Professor
Academic Degrees
- Dr. Engineering, Hiroshima University
- Master of Engineering, Hiroshima University
Educational Activity
- [Bachelor Degree Program] School of Engineering : Cluster 3(Applied Chemistry, Biotechnology and Chemical Engineering) : Program of Biotechnology
- [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology
- [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology
In Charge of Primary Major Programs
Research Fields
- Agricultural sciences;Agricultural chemistry;Applied microbiology
Research Keywords
- environmental biotecnology
- bacteria
- inorganic phosphorus compounds
- reduced phosphorus compounds
- molecular biology
Affiliated Academic Societies
- American society for microbiology
- The Society for Biotechnology
- The Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Japan Society for Environmental Biotechnology
Educational Activity
Course in Charge
- 2023, Undergraduate Education, 1Term, Biochemistry I
- 2023, Undergraduate Education, Second Semester, Basic Experiments in Chemistry
- 2023, Undergraduate Education, 4Term, Basic life science
- 2023, Undergraduate Education, First Semester, Training of Biotechnology I
- 2023, Graduate Education (Master's Program) , 3Term, Research Methods in Life Science
- 2023, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
- 2023, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
- 2023, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
- 2023, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
- 2023, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B
- 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biotechnology
- 2023, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences
Research Activities
Academic Papers
- A Novel Pathway for Biosynthesis of the Herbicidal Phosphonate Natural Product Phosphonothrixin Is Widespread in Actinobacteria, Journal of Bacteriology, e00485-22, 20230419
- Assessment of horizontal gene transfer-mediated destabilization of Synechococcus elongatus PCC 7942 biocontainment system, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 135(3), 190-195, 202303
- ★, Biodiversity risk assessment of genetically modified Chaetoceros gracilis for outdoor cultivation, The Journal of General and Applied Microbiology, 68(3), 151-162, 2022
- ★, Gatekeeper Residue Replacement in a Phosphite Transporter Enhances Mutational Robustness of the Biocontainment Strategy, ACS SYNTHETIC BIOLOGY, 11(10), 3397-3404, 20221021
- Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 9, 20210401
- Phosphite Reduces the Predation Impact of Poterioochromonas malhamensis on Cyanobacterial Culture, Plants, 10(7), 1361, 20210702
- Biological Phosphite Oxidation and Its Application to Phosphorus Recycling, Phosphorus Recovery and Recycling, 499-514, 20180326
- ★, Synthetic Phosphorus Metabolic Pathway for Biosafety and Contamination Management of Cyanobacterial Cultivation, ACS Synthetic Biology, 20180911
- ★, A Novel Biocontainment Strategy Makes Bacterial Growth and Survival Dependent on Phosphite, SCIENTIFIC REPORTS, 7, 20170320
- A Lactobacillus mutant capable of accumulating long-chain polyphosphates that enhance intestinal barrier function, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 80(5), 955-961, 201605
- Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(39), 12175-12180, 20150929
- ★, Environmental biotechnology for efficient utilization of industrial phosphite waste, Global Environ Res, 19(1), 77-82, 2015
- ★, A New Subfamily of Polyphosphate Kinase 2 (Class III PPK2) Catalyzes both Nucleoside Monophosphate Phosphorylation and Nucleoside Diphosphate Phosphorylation, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(8), 2602-2608, 201404
- ★, Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts, JOURNAL OF BIOTECHNOLOGY, 182, 68-73, 20140720
- ★, Stable polyphosphate accumulation by a pseudo-revertant of an Escherichia coli phoU mutant, BIOTECHNOLOGY LETTERS, 35(5), 695-701, 201305
- ★, Isolation and characterization of a soluble and thermostable phosphite dehydrogenase from Ralstonia sp strain 4506, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 113(4), 445-450, 201204
- Construction of membrane-anchoring fusion protein of Thermococcus kodakaraensis glycerol kinase and its application to repetitive batchwise reactions, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 113(4), 521-525, 201204
- Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway, MICROBIAL CELL FACTORIES, 11, 20120906
- Overproduction of YjbB reduces the level of polyphosphate in Escherichia coli: a hypothetical role of YjbB in phosphate export and polyphosphate accumulation, FEMS MICROBIOLOGY LETTERS, 320(1), 25-32, 201107
- Feasibility of thermophilic adenosine triphosphate-regeneration system using Thermus thermophilus polyphosphate kinase, PROCESS BIOCHEMISTRY, 46(9), 1747-1752, 201109
- ★, Bacterial phosphate metabolism and its application to phosphorus recovery and industrial bioprocesses, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 109(5), 423-432, 201005
- Production of 2-deoxyribose 5-phosphate from fructose to demonstrate a potential of artificial bio-synthetic pathway using thermophilic enzymes, JOURNAL OF BIOTECHNOLOGY, 148(4), 204-207, 20100802
- ★, The silicon layer supports acid resistance of Bacillus cereus spore, JOURNAL OF BACTERIOLOGY, 20100101
- Reciprocating-flow ATP amplification system for increasing the number of amplification cycles, ANALYTICAL BIOCHEMISTRY, 395(2), 161-165, 20091215
- Continuous-Flow ATP amplification system on a chip, SENSORS AND ACTUATORS B-CHEMICAL, 142(1), 118-122, 20091012
- Transcriptional Analysis of the Multicopy hao Gene Coding for Hydroxylamine Oxidoreductase in Nitrosomonas sp. Strain ENI-11, Biosci. Biotechnol. Biochem., 1875-1881, 20070823
- ★, Use of an Escherichia coli recombinant producing thermostable polyphosphate kinase as an ATP regenerator to produce fructose 1,6-diphosphate, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(17), 5676-5678, 200709
- ★, Transcriptional analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 70(8), 1875-1881, 200608
- ★, Isolation and characterization of cbbL and cbbS genes encoding form I ribulose-1,5-bisphosphate carboxylase/oxygenase large and small subunits in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66(3), 632-635, 200203
- Molecular analysis of the nitrification henes in Nitrosomonas sp. strain ENI-11, Proceedings of 5th International Symposium on Environmental Biotechmology, 67-70, 20010701
- ★, Mutational analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in the ammonia-oxidizing bacterium Nitrosomonas sp. strain ENI-11, Biosc. Biochem. Biotechnol., 64, 1754-1757, 20000401
- ★, Physical map location of the multicopy genes coding for ammonia monooxygenase and hydroxylamine oxidoreductase in the ammonia-oxidizing bacterium Nitrosomonas sp strain ENI-11, JOURNAL OF BACTERIOLOGY, 182(3), 825-828, 200002
- Mutational analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 64(8), 1754-1757, 200008
- ★, Isolation and characterization of two cryptic plasmids in the ammonia-oxidizing bacterium Nitrosomonas sp. strain ENI-11, JOURNAL OF BACTERIOLOGY, 181, 3375-3381, 19990401
- Biodiversity risk assessment of genetically modified Chaetoceros gracilis for outdoor cultivation, The Journal of General and Applied Microbiology, 20220531