RYUICHI HIROTA

Last Updated :2023/06/01

Affiliations, Positions
Graduate School of Integrated Sciences for Life, Associate Professor
Web Site
http://home.hiroshima-u.ac.jp/akbio/
E-mail
hirotahiroshima-u.ac.jp

Basic Information

Major Professional Backgrounds

  • 2007/03/01, 2017/05/31, Graduate School of Advanced Sciences of Matter, Assistant Professor
  • 2013/09/28, 2014/11/28, University of Illinois Urbana-Champaign, Visiting Scholar
  • 2017/06/01, 2019/03/31, Graduate School of Advanced Sciences of Matter, Associate Professor
  • 2019/04/01, Graduate School of Integrated Sciences for Life, Associate Professor

Academic Degrees

  • Dr. Engineering, Hiroshima University
  • Master of Engineering, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Engineering : Cluster 3(Applied Chemistry, Biotechnology and Chemical Engineering) : Program of Biotechnology
  • [Master's Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology
  • [Doctoral Program] Graduate School of Integrated Sciences for Life : Division of Integrated Sciences for Life : Program of Biotechnology

In Charge of Primary Major Programs

  • Biotechnology

Research Fields

  • Agricultural sciences;Agricultural chemistry;Applied microbiology

Research Keywords

  • environmental biotecnology
  • bacteria
  • inorganic phosphorus compounds
  • reduced phosphorus compounds
  • molecular biology

Affiliated Academic Societies

  • American society for microbiology
  • The Society for Biotechnology
  • The Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • Japan Society for Environmental Biotechnology

Educational Activity

Course in Charge

  1. 2023, Undergraduate Education, 1Term, Biochemistry I
  2. 2023, Undergraduate Education, Second Semester, Basic Experiments in Chemistry
  3. 2023, Undergraduate Education, 4Term, Basic life science
  4. 2023, Undergraduate Education, First Semester, Training of Biotechnology I
  5. 2023, Graduate Education (Master's Program) , 3Term, Research Methods in Life Science
  6. 2023, Graduate Education (Master's Program) , Academic Year, Seminar in Biotechnology
  7. 2023, Graduate Education (Master's Program) , 1Term, Exercises in Biotechnology A
  8. 2023, Graduate Education (Master's Program) , 2Term, Exercises in Biotechnology A
  9. 2023, Graduate Education (Master's Program) , 3Term, Exercises in Biotechnology B
  10. 2023, Graduate Education (Master's Program) , 4Term, Exercises in Biotechnology B
  11. 2023, Graduate Education (Master's Program) , Academic Year, Research for Academic Degree Dissertation in Biotechnology
  12. 2023, Graduate Education (Doctoral Program) , Academic Year, Research for Academic Degree Dissertation in Integrated Life Sciences

Research Activities

Academic Papers

  1. A Novel Pathway for Biosynthesis of the Herbicidal Phosphonate Natural Product Phosphonothrixin Is Widespread in Actinobacteria, Journal of Bacteriology, e00485-22, 20230419
    Link to Paper Search Results by DOI
  2. Assessment of horizontal gene transfer-mediated destabilization of Synechococcus elongatus PCC 7942 biocontainment system, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 135(3), 190-195, 202303
    Link to Paper Search Results by DOI
  3. ★, Biodiversity risk assessment of genetically modified Chaetoceros gracilis for outdoor cultivation, The Journal of General and Applied Microbiology, 68(3), 151-162, 2022
  4. ★, Gatekeeper Residue Replacement in a Phosphite Transporter Enhances Mutational Robustness of the Biocontainment Strategy, ACS SYNTHETIC BIOLOGY, 11(10), 3397-3404, 20221021
    Link to Paper Search Results by DOI
  5. Engineering Cofactor Specificity of a Thermostable Phosphite Dehydrogenase for a Highly Efficient and Robust NADPH Regeneration System, FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 9, 20210401
    Link to Paper Search Results by DOI
  6. Phosphite Reduces the Predation Impact of Poterioochromonas malhamensis on Cyanobacterial Culture, Plants, 10(7), 1361, 20210702
  7. Biological Phosphite Oxidation and Its Application to Phosphorus Recycling, Phosphorus Recovery and Recycling, 499-514, 20180326
  8. ★, Synthetic Phosphorus Metabolic Pathway for Biosafety and Contamination Management of Cyanobacterial Cultivation, ACS Synthetic Biology, 20180911
    Link to Paper Search Results by DOI
  9. ★, A Novel Biocontainment Strategy Makes Bacterial Growth and Survival Dependent on Phosphite, SCIENTIFIC REPORTS, 7, 20170320
    Link to Paper Search Results by DOI
  10. A Lactobacillus mutant capable of accumulating long-chain polyphosphates that enhance intestinal barrier function, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 80(5), 955-961, 201605
    Link to Paper Search Results by DOI
  11. Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(39), 12175-12180, 20150929
    Link to Paper Search Results by DOI
  12. ★, Environmental biotechnology for efficient utilization of industrial phosphite waste, Global Environ Res, 19(1), 77-82, 2015
  13. ★, A New Subfamily of Polyphosphate Kinase 2 (Class III PPK2) Catalyzes both Nucleoside Monophosphate Phosphorylation and Nucleoside Diphosphate Phosphorylation, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(8), 2602-2608, 201404
    Link to Paper Search Results by DOI
  14. ★, Application of a phosphite dehydrogenase gene as a novel dominant selection marker for yeasts, JOURNAL OF BIOTECHNOLOGY, 182, 68-73, 20140720
    Link to Paper Search Results by DOI
  15. ★, Stable polyphosphate accumulation by a pseudo-revertant of an Escherichia coli phoU mutant, BIOTECHNOLOGY LETTERS, 35(5), 695-701, 201305
    Link to Paper Search Results by DOI
  16. ★, Isolation and characterization of a soluble and thermostable phosphite dehydrogenase from Ralstonia sp strain 4506, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 113(4), 445-450, 201204
    Link to Paper Search Results by DOI
  17. Construction of membrane-anchoring fusion protein of Thermococcus kodakaraensis glycerol kinase and its application to repetitive batchwise reactions, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 113(4), 521-525, 201204
    Link to Paper Search Results by DOI
  18. Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway, MICROBIAL CELL FACTORIES, 11, 20120906
    Link to Paper Search Results by DOI
  19. Overproduction of YjbB reduces the level of polyphosphate in Escherichia coli: a hypothetical role of YjbB in phosphate export and polyphosphate accumulation, FEMS MICROBIOLOGY LETTERS, 320(1), 25-32, 201107
    Link to Paper Search Results by DOI
  20. Feasibility of thermophilic adenosine triphosphate-regeneration system using Thermus thermophilus polyphosphate kinase, PROCESS BIOCHEMISTRY, 46(9), 1747-1752, 201109
    Link to Paper Search Results by DOI
  21. ★, Bacterial phosphate metabolism and its application to phosphorus recovery and industrial bioprocesses, JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 109(5), 423-432, 201005
    Link to Paper Search Results by DOI
  22. Production of 2-deoxyribose 5-phosphate from fructose to demonstrate a potential of artificial bio-synthetic pathway using thermophilic enzymes, JOURNAL OF BIOTECHNOLOGY, 148(4), 204-207, 20100802
    Link to Paper Search Results by DOI
  23. ★, The silicon layer supports acid resistance of Bacillus cereus spore, JOURNAL OF BACTERIOLOGY, 20100101
  24. Reciprocating-flow ATP amplification system for increasing the number of amplification cycles, ANALYTICAL BIOCHEMISTRY, 395(2), 161-165, 20091215
    Link to Paper Search Results by DOI
  25. Continuous-Flow ATP amplification system on a chip, SENSORS AND ACTUATORS B-CHEMICAL, 142(1), 118-122, 20091012
    Link to Paper Search Results by DOI
  26. Transcriptional Analysis of the Multicopy hao Gene Coding for Hydroxylamine Oxidoreductase in Nitrosomonas sp. Strain ENI-11, Biosci. Biotechnol. Biochem., 1875-1881, 20070823
  27. ★, Use of an Escherichia coli recombinant producing thermostable polyphosphate kinase as an ATP regenerator to produce fructose 1,6-diphosphate, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(17), 5676-5678, 200709
    Link to Paper Search Results by DOI
  28. ★, Transcriptional analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 70(8), 1875-1881, 200608
    Link to Paper Search Results by DOI
  29. ★, Isolation and characterization of cbbL and cbbS genes encoding form I ribulose-1,5-bisphosphate carboxylase/oxygenase large and small subunits in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 66(3), 632-635, 200203
    Link to Paper Search Results by DOI
  30. Molecular analysis of the nitrification henes in Nitrosomonas sp. strain ENI-11, Proceedings of 5th International Symposium on Environmental Biotechmology, 67-70, 20010701
  31. ★, Mutational analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in the ammonia-oxidizing bacterium Nitrosomonas sp. strain ENI-11, Biosc. Biochem. Biotechnol., 64, 1754-1757, 20000401
  32. ★, Physical map location of the multicopy genes coding for ammonia monooxygenase and hydroxylamine oxidoreductase in the ammonia-oxidizing bacterium Nitrosomonas sp strain ENI-11, JOURNAL OF BACTERIOLOGY, 182(3), 825-828, 200002
    Link to Paper Search Results by DOI
  33. Mutational analysis of the multicopy hao gene coding for hydroxylamine oxidoreductase in Nitrosomonas sp strain ENI-11, BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 64(8), 1754-1757, 200008
    Link to Paper Search Results by DOI
  34. ★, Isolation and characterization of two cryptic plasmids in the ammonia-oxidizing bacterium Nitrosomonas sp. strain ENI-11, JOURNAL OF BACTERIOLOGY, 181, 3375-3381, 19990401
  35. Biodiversity risk assessment of genetically modified Chaetoceros gracilis for outdoor cultivation, The Journal of General and Applied Microbiology, 20220531