Kazuaki Tanabe
Last Updated :2021/01/05
- Affiliations, Positions
- Graduate School of Biomedical and Health Sciences(Health Sciences), Professor
- E-mail
- ktanabe2
hiroshima-u.ac.jp
- Other Contact Details
- 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan, Japan
TEL : (+81)82-257-5380 FAX : (+81)82-257-5384
- Self-introduction
- Clinical and basic research for upper gastroenterological surgery
Basic Information
Educational Backgrounds
- Hiroshima University, Graduate School, Division of Medicine, Japan, 2000/04, 2003/03
- Hiroshima University, Faculty of Medicine, Japan, 1988/04, 1994/03
Academic Degrees
- Doctor of Philosophy in Medical Science, Hiroshima University
Educational Activity
- 【Bachelor Degree Program】School of Medicine : Program of Health Sciences
- 【Master's Program】Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
- 【Doctoral Program】Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
In Charge of Primary Major Programs
Research Fields
- Medicine,dentistry, and pharmacy;Clinical surgery;Digestive surgery
Research Keywords
- Wnt signaling
- Cancer stem cell
- Cancer
Affiliated Academic Societies
- Japan Gastric Cancer Association
Educational Activity
Course in Charge
- 2020, Undergraduate Education, Second Semester, Physiology II
- 2020, Undergraduate Education, Second Semester, Physiology II
- 2020, Undergraduate Education, Year, Clinical diagnosis and treatment I
- 2020, Undergraduate Education, Intensive, Symptomatology, Diagnosis and Treatment
- 2020, Undergraduate Education, Intensive, Integrated Clinical Practice
- 2020, Undergraduate Education, Second Semester, Practice in Basic Medicine
- 2020, Undergraduate Education, 2Term, Clinical pharmacology
- 2020, Undergraduate Education, 1Term, Microbiology Immunology
- 2020, Undergraduate Education, First Semester, Disease Management in Adult
- 2020, Undergraduate Education, Second Semester, Organ Response for Surgical Injury
- 2020, Undergraduate Education, Year, Graduate thesis
- 2020, Undergraduate Education, Intensive, Clinical Practice in Acute Care Nursing
- 2020, Undergraduate Education, Second Semester, Anatomy and Physiology II
- 2020, Undergraduate Education, 1Term, Lecture of Patho-physiology for Adult Diseases
- 2020, Undergraduate Education, 4Term, Principles of Rehabilitation
- 2020, Undergraduate Education, 2Term, Introduction to Rehabilitation Science
- 2020, Undergraduate Education, 2Term, Introduction to Rehabilitation Science
- 2020, Undergraduate Education, Second Semester, Emergency Medicine and Infection Control
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Lecture on Health Promotion
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Lecture on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Lecture on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , Year, Advanced Research on Development of Nursing Science
- 2020, Graduate Education (Doctoral Program) , First Semester, Practice of Oncology
- 2020, Graduate Education (Doctoral Program) , 1Term, Practice of Oncology
- 2020, Graduate Education (Doctoral Program) , Second Semester, Methodology of Education for Health Promotion
- 2020, Graduate Education (Master's Program) , First Semester, Advanced Lecture on Health Science 1(Survey Research)
- 2020, Graduate Education (Master's Program) , First Semester, Advanced Lecture on Health Science 1(Survey Research)
- 2020, Graduate Education (Master's Program) , First Semester, Advanced Lecture on Health Science 3(Experiment Research)
- 2020, Graduate Education (Master's Program) , First Semester, Advanced Lecture on Health Science 3(Experiment Research)
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Development of Nursing Science
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Development of Nursing Science
- 2020, Graduate Education (Master's Program) , First Semester, Lecture on Health Care for Adults
- 2020, Graduate Education (Master's Program) , First Semester, Lecture on Health Care for Adults
- 2020, Graduate Education (Master's Program) , First Semester, Seminar on Health Care for Adults
- 2020, Graduate Education (Master's Program) , Second Semester, Seminar on Health Care for Adults
- 2020, Graduate Education (Master's Program) , First Semester, Seminar on Health Care for Adults
- 2020, Graduate Education (Master's Program) , Second Semester, Seminar on Health Care for Adults
- 2020, Graduate Education (Master's Program) , Year, Research on Health Care for Adults
- 2020, Graduate Education (Master's Program) , Year, Methodology of Education for Health Care for Adults
- 2020, Graduate Education (Master's Program) , Year, Educational Practice on Health Care for Adults
- 2020, Graduate Education (Master's Program) , Year, Integrated Educational Practice on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Lecture on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Lecture on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Health Care for Adults
- 2020, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Health Care for Adults
Research Activities
Academic Papers
- ★, Phase II/III study of second-line chemotherapy comparing irinotecan-alone with S-1 plus irinotecan in advanced gastric cancer refractory to first-line treatment with S-1 (JACCRO GC-05)., Ann Oncol, 26, 1916-1922, 2015
- Initial experiences of robotic versus conventional laparoscopic surgery for colorectal cancer, focusing on short-term outcomes: a matched case-control study, WORLD JOURNAL OF SURGICAL ONCOLOGY, 13, 20150312
- ★, Sequential paclitaxel followed by tegafur and uracil (UFT) or S-1 versus UFT or S-1 monotherapy as adjuvant chemotherapy for T4a/b gastric cancer (SAMIT): a phase 3 factorial randomised controlled trial, LANCET ONCOLOGY, 15(8), 886-893, 201407
- ★, Hypoxia-mediated CD24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasion., Cancer Science, 105, 1411-1420, 20140901
- ★, Fasting Enhances TRAIL-Mediated Liver Natural Killer Cell Activity via HSP70 Upregulation, PLOS ONE, 9(10), 20141030
- Risk factors for surgical complications after D2 gastrectomy following neoadjuvant chemotherapy for gastric cancer., J Clin Oncol, 32(Suppl 3), abstr 164, 20140101
- ★, Induction of a Pathological Complete Response by Four Courses of Neoadjuvant Chemotherapy for Gastric Cancer: Early Results of the Randomized Phase II COMPASS Trial, ANNALS OF SURGICAL ONCOLOGY, 21(1), 213-219, 201401
- Low Creatinine Clearance is a Risk Factor for D2 Gastrectomy after Neoadjuvant Chemotherapy, ANNALS OF SURGICAL ONCOLOGY, 21(9), 3015-3022, 201409
- Accuracy of CT Staging of Locally Advanced Gastric Cancer after Neoadjuvant Chemotherapy: Cohort Evaluation within a Randomized Phase II Study, ANNALS OF SURGICAL ONCOLOGY, 21, 385-389, 201406
- ★, Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 and Changes in Body Weight are Useful Tools for Evaluation of Reconstruction Methods Following Distal Gastrectomy, ANNALS OF SURGICAL ONCOLOGY, 21, 370-378, 201406
- ★, Double-blind, placebo-controlled, randomized phase II study of TJ-14 (hangeshashinto) for gastric cancer chemotherapy-induced oral mucositis, CANCER CHEMOTHERAPY AND PHARMACOLOGY, 73(5), 1047-1054, 201405
- ★, The Usefulness of Preoperative 18FDG Positron-Emission Tomography and Computed Tomography for Predicting the Malignant Potential of Gastrointestinal Stromal Tumors, DIGESTIVE SURGERY, 31(2), 79-86, 2014
- ★, Addition of docetaxel to S-1 without platinum prolongs survival of patients with advanced gastric cancer: a randomized study (START), JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 140(2), 319-328, 201402
- A large esophageal gastrointestinal stromal tumor that was successfully resected after neoadjuvant imatinib treatment: case report, WORLD JOURNAL OF SURGICAL ONCOLOGY, 12, 20140227
- A case of gastric cancer following living donor liver transplantation., Hiroshima J Med Sci, 63, 23-26, 2014
- Assessment of postoperative quality of life following pylorus-preserving gastrectomy and Billroth-I distal gastrectomy in gastric cancer patients: results of the nationwide postgastrectomy syndrome assessment study, GASTRIC CANCER, 19(1), 302-311, 201601
- Specific Features of Dumping Syndrome after Various Types of Gastrectomy as Assessed by a Newly Developed Integrated Questionnaire, the PGSAS-45, DIGESTIVE SURGERY, 33(2), 94-103, 2016
- Intraoperative assessment of tissue oxygen saturation of the remnant stomach by near-infrared spectroscopy in two cases of pancreatectomy following gastrectomy, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 22, 75-78, 2016
- Enhanced recovery program is safe and improves postoperative insulin resistance in gastrectomy, WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 8(5), 382-388, 20160527
- Survival results of a randomised two-by-two factorial phase II trial comparing neoadjuvant chemotherapy with two and four courses of S-1 plus cisplatin (SC) and paclitaxel plus cisplatin (PC) followed by D2 gastrectomy for resectable advanced gastric cancer, EUROPEAN JOURNAL OF CANCER, 62, 103-111, 201607
- Feasibility and Safety of Transhiatal Approach and D2 Total Gastrectomy after Neoadjuvant Chemotherapy for Adenocarcinoma of the Esophago-Gastric Junction: A Subset Analysis of the COMPASS Trial, DIGESTIVE SURGERY, 33(5), 424-430, 2016
- Laparoscopic Repair and Percutaneous Endoscopic Gastrostomy to Treat Giant Esophageal Hiatal Hernia with Gastric Obstruction: A Case Report., Hiroshima J Med Sci, 64(1-2), 27-30, 2015
- Assessment of postoperative quality of life following pylorus-preserving gastrectomy and Billroth-I distal gastrectomy in gastric cancer patients: results of the nationwide postgastrectomy syndrome assessment study., Gastric Cancer, 19(1), 302-311, 2015
- Intrahepatic cholangiocarcinoma coinciding with a liver metastasis from a rectal carcinoma: a case report, SURGICAL CASE REPORTS, 2, 20160909
- Overexpression of Transmembrane Protein BST2 is Associated with Poor Survival of Patients with Esophageal, Gastric, or Colorectal Cancer., Ann Surg Oncol
- Laparoscopic extra-abdominal suturing technique for the repair of Larrey's diaphragmatic hernia using the port closure needle (Endo Close(R)): A case report., Int J Surg Case Rep, 2016
- Possible role of soluble fibrin monomer complex after gastroenterological surgery, WORLD JOURNAL OF GASTROENTEROLOGY, 23(12), 2209-2216, 2017, 5, 28
- ★, Predictive factors for body weight loss and its impact on quality of life following gastrectomy, WORLD JOURNAL OF GASTROENTEROLOGY, 23(26), 4823-4830, 2017, 07, 14
- ★, Early results of a randomized two-by-two factorial phase II trial comparing neoadjuvant chemotherapy with two and four courses of cisplatin/S-1 and docetaxel/cisplatin/S-1 as neoadjuvant chemotherapy for locally advanced gastric cancer, ANNALS OF ONCOLOGY, 28(8), 1876-1881, 2017, 08
- PRESENT STATUS AND PROBLEMATIC POINTS OF DAY SURGERY OF BREAST CANCER, 60(9), 2283-2290, 19990925
- Kidney Metastasis of Resected Early Gastric Carcinoma : Report of a Case, 37(3), 248-250, 20070301
- A STUDY ON THE ADEQUATE EXTENT OF DISSECTION OF REGIONAL LYMPH NODES FOR t_2 AND t_3 GASTRIC CANCER, 60(12), 3088-3092, 19991225
- Overexpression of PCDHB9 promotes peritoneal metastasis and correlates with poor prognosis in patients with gastric cancer, JOURNAL OF PATHOLOGY, 243(1), 100-110, 2017, 09
- A rare case of spontaneous rupture of an aneurysm of the right gastric artery, INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 40, 27-31, 2017
- The gastric carcinosarcoma with severe venous invasion: a case report, SURGICAL CASE REPORTS, 4, 20180130
- The long-term survival of stage IV gastric cancer patients with conversion therapy, GASTRIC CANCER, 21(2), 315-323, 201803
- Clinicopathological and Prognostic Significance of Epithelial Gremlin1 Expression in Gastric Cancer, ANTICANCER RESEARCH, 38(3), 1419-1425, 201803
- The clinical impact of Hangeshashinto (TJ-14) in the treatment of chemotherapy-induced oral mucositis in gastric cancer and colorectal cancer: Analyses of pooled data from two phase II randomized clinical trials (HANGESHA-G and HANGESHA-C), JOURNAL OF CANCER, 9(10), 1725-1730, 2018
- A phase II trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer with early relapse after S-1 adjuvant therapy: XParTS-I trial, GASTRIC CANCER, 21(5), 811-818, 201809
- Revascularization for cavernous transformation radical lymphadenectomy in the treatment of gastric cancer: A case report., Int J Surg Case Rep, 50, 84-87, 2018
- Palliative surgery for advanced gastric cancer: Partial gastrectomy using the inverted laparoscopic and endoscopic cooperative surgery method., Int J Surg Case Rep, 50, 42-45, 2018
- A randomised phase II trial of capecitabine plus cisplatin versus S-1 plus cisplatin as a first-line treatment for advanced gastric cancer: Capecitabine plus cisplatin ascertainment versus S-1 plus cisplatin randomised PII trial (XParTS II)., Eur J Cancer, 101, 220-228, 2018
- Laparoscopic proximal gastrectomy with hinged double flap method using knotless barbed absorbable sutures: A case series., Int J Surg Case Rep, 51, 165-169, 2018
- A phase II trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer with early relapse after S-1 adjuvant therapy: XParTS-I trial., Gastric Cancer, 21(5), 811-818, 2018
Invited Lecture, Oral Presentation, Poster Presentation
- A randomized phase II trial of capecitabine plus cisplatin (XP) versus S-1 plus cisplatin (SP) as a first-line treatment for advanced gastric cancer: XP ascertainment vs. SP randomized PII trial (XParTS II), Kobayashi M, Tanabe K et al., ASCO-GI, 2015/01/15, Without Invitation, English
- A randomized 2X2 phase II trial comparing two and four courses of S-1/cisplatin (SC) and paclitaxel/cisplatin (PC) as neoadjuvant chemotherapy for locally resectable advanced gastric cancer: Survival results of COMPASS., Yoshikawa T, Tanabe K et al., ASCO-GI, 2015, 2015/01/15, Without Invitation, English
- A phase II trial of capecitabine plus cisplatin (XP) for patients with advanced gastric cancer who relapsed after S-1 adjuvant therapy, XP after TS-1 adjuvant failure (XParTS)., Takahashi M, Tanabe K et al., ASCO-GI, 2015, 2015/01/15, Without Invitation, English
Awards
- 2015/11/13, Phoenix Outstanding Researcher Award, Hiroshima University