Takashi Nakamoto

Last Updated :2024/06/04

Affiliations, Positions
Graduate School of Biomedical and Health Sciences(Dentistry & Oral Health Sciences), Associate Professor
E-mail
tnkhiroshima-u.ac.jp
Self-introduction
Research: I mainly conduct research on osteoporosis screening from dental panoramic X-ray images. Education: I am in charge of education of maxillofacial image diagnosis. Work in hospital:I am engaged exclusively in diagnostic imaging for maxillofacial area.

Basic Information

Major Professional Backgrounds

  • 2008/07/01, Hiroshima University Hospital, Oral and Maxillofacial Radiology, Senior Lecturer
  • 2019/10/01, Hiroshima University, Graduate School of Biomedical and Health Sciences, Associate Professor

Educational Backgrounds

  • Hiroshima University, Graduate School, Division of Dental Research, Oral and Maxillofacial Radiology, Japan, 2000/04, 2004/03
  • The University of Tokushima, Faculty of Dentistry, Division of Dentistry, Japan, 1994/04, 2000/03

Academic Degrees

  • Doctor of Philosophy, Hiroshima University

Educational Activity

  • [Bachelor Degree Program] School of Dentistry : Program of Dentistry : Dentistry
  • [Master's Program] Graduate School of Biomedical and Health Sciences : Division of Integrated Health Sciences
  • [Doctoral Program] Graduate School of Biomedical and Health Sciences : Division of Biomedical Sciences

In Charge of Primary Major Programs

  • Dentistry

Research Fields

  • Medicine,dentistry, and pharmacy;Dentistry;Pathobiological dentistry / Dental radiology

Research Keywords

  • screening
  • radiographs
  • jaw
  • osteoporosis
  • bisphosphonate

Affiliated Academic Societies

  • Japanese Society of Pediatric Dentistry
  • The Hiroshima University Dental Society
  • The Japanese Society of Medical Imaging Technology
  • Japanese Society for Oral and Maxillofacial Radiology

Educational Activity

Course in Charge

  1. 2024, Liberal Arts Education Program1, 2Term, General Health and Oral Sciences I
  2. 2024, Undergraduate Education, 1Term, Medical Ethics
  3. 2024, Undergraduate Education, First Semester, Early Clinical Exposure I
  4. 2024, Undergraduate Education, 2Term, Oral Radiology I
  5. 2024, Undergraduate Education, 3Term, Oral Radiology II
  6. 2024, Undergraduate Education, 4Term, Basic Seminar of Oral Radiology
  7. 2024, Undergraduate Education, Second Semester, Early Clinical Exposure II
  8. 2024, Undergraduate Education, First Semester, Dental Research Practices I
  9. 2024, Undergraduate Education, Second Semester, Early Clinical Exposure III
  10. 2024, Undergraduate Education, Second Semester, Dental Research Practices II
  11. 2024, Undergraduate Education, First Semester, Dental Research Practices III
  12. 2024, Undergraduate Education, Academic Year, Clinical Practice (Dental Radiology)
  13. 2024, Undergraduate Education, 1Term, Medical ethics
  14. 2024, Undergraduate Education, 3Term, Oral Radiology
  15. 2024, Undergraduate Education, Second Semester, Clinical Practice on Oral Health
  16. 2024, Undergraduate Education, Intensive, Clinical practice on oral health
  17. 2024, Undergraduate Education, Intensive, Clinical Practice on Oral Health Management
  18. 2024, Undergraduate Education, 1Term, Medical ethics
  19. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Seminar on Oral and Maxillofacial Radiology
  20. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Seminar on Oral and Maxillofacial Radiology
  21. 2024, Graduate Education (Doctoral Program) , First Semester, Advanced Research on Oral and Maxillofacial Radiology
  22. 2024, Graduate Education (Doctoral Program) , Second Semester, Advanced Research on Oral and Maxillofacial Radiology

Research Activities

Academic Papers

  1. Image preprocessing with contrast-limited adaptive histogram equalization improves the segmentation performance of deep learning for the articular disk of the temporomandibular joint on magnetic resonance images., Oral Surg Oral Med Oral Pathol Oral Radiol, 2023
  2. Intra- and inter-examination reproducibility of T2 mapping for temporomandibular joint assessment at 3.0 T, SCIENTIFIC REPORTS, 12(1), 20220629
  3. ★, Osteoporosis screening support system from panoramic radiographs using deep learning by convolutional neural network, Dentomaxillofacial Radiology, 51, 202207
  4. Cancellous bone-like tissue replacement from calcinosis in patients with systemic sclerosis with multiple external root resorption, BONE REPORTS, 16, 202206
  5. Relationship between dental panoramic radiographic findings and biochemical markers of bone turnover, J. Bone Miner. Res., 18(9), 1689-1694, 20030401
  6. Association of estrogen and vitamin D receptor gene polymorphisms with tooth loss and oral bone loss in Japanese postmenopausal women, Menopause-Journal of the North America Menopause Society, 10, 250-257, 20030401
  7. Relationship between dental panoramic radiographic findings and biochemical markers of bone turnover, J. Bone Miner. Res., 18, 1689-1694, 20030401
  8. ★, Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: Untrained general dental practitioners diagnostic performance, Osteoporos Int, 14, 659-664, 20030401
  9. Detection of vascular disease risk in women by panoramic radiograph, J. Dent. Res., 82, 838-843, 20030401
  10. Effect of estrogen use on tooth retention, oral bone height, and oral bone porosity in Japanese postmenopausal women, Menopause-Journal of the North America Menopause Society, 11(5), 556-62, 20041001
  11. Validation of dental panoramic radiographic measures in identifying postmenopausal women with spinal osteoporosis, American Journal of Roentgenology, 183(6), 1755-60, 20041201
  12. Use of dental panoramic radiographs in identifying younger postmenopausal women with osteoporosis, Osteoporos Int, 17(3), 387-94, 20060301
  13. Screening for osteoporosis by dental panoramic radiographs, Clinical Calcium, 16(2), 291-7, 20060201
  14. Diagnostic performance of general dental practitioners after lecture in identifying postmenopausal women with low bone mineral density by panoramic radiographs, Dentomaxillofacial Radiology, 35(4), 249-52, 20060901
  15. Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis, Dentomaxillofacial Radiology, 36(1), 28-33, 20070101
  16. Identification of postmenopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs, Dentomaxillofacial Radiology, 36(3), 149-54, 20070301
  17. Risk for vertebral osteoporosis in postmenopausal women with alterations of the mandible, Dentomaxillofacial Radiology, 36(3), 143-8, 20070301
  18. Interaction of obesity and skeletal bone mineral density on tooth retention in Japanese postmenopausal women, Menopause-Journal of the North America Menopause Society, 14, 500-4, 20070501
  19. ★, Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: Untrained general dental practitioners diagnostic performance., Osteoporos Int, 14(8), 659-64., 20030401
  20. Association of estrogen and vitamin D receptor gene polymorphisms with tooth loss and oral bone loss in Japanese postmenopausal women, Menopause, 10(3), 250-257., 20030401
  21. Detection of Vascular Disease Risk in Women by Panoramic Radiography, J. Dent. Res., 82(10), 838-843, 20030401
  22. Effect of estrogen use on tooth retention, oral bone height, and oral bone porosity in Japanese postmenopausal women. , 2004;11:, Menopause, 11, 556-562., 20040401
  23. Validation of dental panoramic radiographic measures in identifying postmenopausal women with spinal osteoporosis, AJR Am J Roentgenol, 183, 1755-1760, 20040401
  24. Relationship between self-reported periodontal status and skeletal bone mineral density in Japanese postmenopausal women, Menopause, 12, 144-8, 20050301
  25. Clinical and panoramic predictors of femur bone mineral density, Osteoporos Int, 16, 339-46, 20050301
  26. Visual assessment of the mandibular cortex on panoramic radiographs to identify postmenopausal women with low bone mineral densites, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 100(2), 226-31, 20050801
  27. Diagnostic performance of general dental practitioners after lecture in identifying postmenopausal women with low bone mineral density by panoramic radiographs, Dentomaxillofacial Radiology, 35, 249-252., 20060401
  28. Interaction of obesity and skeletal bone mineral density on tooth retention in Japanese postmenopausal women, Menopause-Journal of the North America Menopause Society, 14, 500-4, 20070501
  29. Risk for vertebral osteoporosis in postmenopausal women with alterations of the mandible, Dentomaxillofacial Radiology, 36(3), 143-8, 20070301
  30. Identification of postmenopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs, Dentomaxillofacial Radiology, 36(3), 149-54, 20070301
  31. Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis, Dentomaxillofacial Radiology, 36(1), 28-33, 20070101
  32. Screening for osteoporosis by dental panoramic radiographs, Clinical Calcium, 16(2), 291-7, 20060201
  33. Visual assessment of the mandibular cortex on panoramic radiographs to identify postmenopausal women with low bone mineral densites, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 100(2), 226-31, 20050801
  34. Use of fuzzy neural network in diagnosing postmenopausal women with osteoporosis based on dental panoramic radiographs, Journal of Advanced Computational Intelligence and Intelligent Informatics, 11(8), 1049-1058, 20071001
  35. Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis, Dentomaxillofacial Radiology, 36(1), 28-33, 20070401
  36. Risk for vertebral osteoporosis in postmenopausal women with alterations of the mandible, Dentomaxillofacial Radiology, 36(3), 143-8, 20070401
  37. Identification of postmenopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs, Dentomaxillofacial Radiology, 36(3), 149-54, 20070401
  38. Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis, Dentomaxillofac Radiol, 20070101
  39. Identification of postmenopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs, Dentomaxillofac Radiol, 20070301
  40. Risk for vertebral osteoporosis in postmenopausal women with alterations of the mandible, Dentomaxillofac Radiol, 20070301
  41. Interaction of obesity and skeletal bone mineral density on tooth retention in Japanese postmenopausal women, Menopause, 20070501
  42. Observer performance in diagnosing osteoporosis by dental panoramic radiographs: results from the osteoporosis screening project in dentistry, Bone, 20080408
  43. Detection of post-menopausal women with low bone mineral density and elevated biochemical markers of bone turnover by panoramic radiographs, Dentomaxillofacial Radiology, 20081201
  44. ★, A computer-aided diagnosis system to screen for osteoporosis using dental panoramic radiographs, Dentomaxillofacial Radiology, 37(5), 274-281, 20080701
  45. Line strength measurement for trabecular bone analysis of mandible on dental panoramic radiographs, Proc. International Workshop on Advanced Image Technology (IWAIT) 2010, 20100101
  46. Cortical Bone Width Measurement Based on Active Shape Models (ASM) on Dental Panoramic Radiograph, Proc. Sixteenth Korea-Japan Joint Workshop on Frontiers of Computer Vision (FCV2010), 20100201
  47. Weighted Fuzzy ARTMAP for Osteoporosis Detection, Proc. Sixteenth Korea-Japan Joint Workshop on Frontiers of Computer Vision (FCV2010), 20100201
  48. Reproducibility and Diagnostic Accuracy of a Computer-aided System of Osteoporosis for Detecting Linearly Eroded Endosteal Margin of the Mandible Lower Border on Panoramic Radiographs, 51(4), 33-38, 20111201
  49. Evaluation of alveolar bone grafting in unilateral cleft lip and palate patients using a computer-aided diagnosis system., Imaging Science in Dentistry, 42(4), 225-229, 20121201
  50. Bone mass of the mandible and the risk of breast cancer among Japanese postmenopausal women., The Breast Journal, 18(1), 93-94, 20120101
  51. Association of estrogen and vitamin D receptor gene polymorphisms with tooth loss and oral bone loss in Japanese postmenopausal Women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 10(3), 250-257, 2003
  52. Relationship between dental panoramic radiographic findings and biochemical markers of bone turnover, JOURNAL OF BONE AND MINERAL RESEARCH, 18(9), 1689-1694, 200309
  53. Dental panoramic radiograph as a tool to detect postmenopausal women with low bone mineral density: untrained general dental practitioners' diagnostic performance, OSTEOPOROSIS INTERNATIONAL, 14(8), 659-664, 200308
  54. Detection of vascular disease risk in women by panoramic radiography, JOURNAL OF DENTAL RESEARCH, 82(10), 838-843, 200310
  55. Effect of estrogen use on tooth retention, oral bone height, and oral bone porosity in Japanese postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 11(5), 556-562, 2004
  56. Validation of dental panoramic radiography measures for identifying postmenopausal women with spinal osteoporosis, AMERICAN JOURNAL OF ROENTGENOLOGY, 183(6), 1755-1760, 200412
  57. Clinical and panoramic predictors of femur bone mineral density, OSTEOPOROSIS INTERNATIONAL, 16(3), 339-346, 200503
  58. Relationship between self-reported periodontal status and skeletal bone mineral density in Japanese postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 12(2), 144-148, 2005
  59. Visual assessment of the mandibular cortex on panoramic radiographs to identify postmenopausal women with low bone mineral densities, ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 100(2), 226-231, 200508
  60. Use of dental panoramic radiographs in identifying younger postmenopausal women with osteoporosis, OSTEOPOROSIS INTERNATIONAL, 17(3), 387-394, 200603
  61. Computer-aided system for measuring the mandibular cortical width on dental panoramic radiographs in identifying postmenopausal women with low bone mineral density, OSTEOPOROSIS INTERNATIONAL, 17(5), 753-759, 200605
  62. Diagnostic performance of general dental practitioners after lecture in identifying post-menopausal women with low bone mineral density by panoramic radiographs, DENTOMAXILLOFACIAL RADIOLOGY, 35(4), 249-252, 200607
  63. Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis, DENTOMAXILLOFACIAL RADIOLOGY, 36(1), 28-33, 200701
  64. Interaction of obesity and skeletal bone mineral density in tooth retention in Japanese postmenopausal women, MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 14(3), 500-504, 2007
  65. Risk of vertebral osteoporosis in post-menopausal women with alterations of the mandible, DENTOMAXILLOFACIAL RADIOLOGY, 36(3), 143-148, 200703
  66. Identification of post-menopausal women at risk of osteoporosis by trained general dental practitioners using panoramic radiographs, DENTOMAXILLOFACIAL RADIOLOGY, 36(3), 149-154, 200703
  67. Observer performance in diagnosing osteoporosis by dental panoramic radiographs: Results from the osteoporosis screening project in dentistry (OSPD), BONE, 43(1), 209-213, 200807
  68. A computer-aided diagnosis system to screen for osteoporosis using dental panoramic radiographs, DENTOMAXILLOFACIAL RADIOLOGY, 37(5), 274-281, 200807
  69. Detection of post-menopausal women with low bone mineral density and elevated biochemical markers of bone turnover by panoramic radiographs, DENTOMAXILLOFACIAL RADIOLOGY, 37(8), 433-437, 200812
  70. ★, A retrospective study of digital subtraction technique to detect sclerotic changes in alveolar bone on intraoral radiographs of bisphosphonate-treated patients, DENTOMAXILLOFACIAL RADIOLOGY, 42(10), 201310
  71. Osteodystrophy in Cholestatic Liver Diseases Is Attenuated by Anti-gamma-Glutamyl Transpeptidase Antibody, PLOS ONE, 10(9), 20150929
  72. Automated Selection of Regions of Interest Using Computer-aided Diagnostic System for Osteoporosis Based on Detection of Linearly Eroded Endosteal Margin of Lower Border of Mandible on Panoramic Radiographs, Dental Radiology, 54(2), 15-21, 2014
  73. A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017), PATHOLOGY INTERNATIONAL, 67(7), 365-369, 201707
  74. Usefulness of subtraction technique to detect sclerotic change in alveolar bone on intra-oral radiographs of oral bisphosphonate-treated patients, 48(2), 107-111, 2016
  75. ★, Improvement of region of interest extraction and scanning method of computer-aided diagnosis system for osteoporosis using panoramic radiographs, ORAL RADIOLOGY, 35(2), 143-151, 201805
  76. Abnormal positioning of the common carotid artery clinically diagnosed as a submandibular mass, ORAL RADIOLOGY, 35(3), 331-334, 201909
  77. The effectiveness of mouthwashes in alleviating radiation-induced oral mucositis in head and neck cancer patients: a systematic review, ORAL RADIOLOGY, 35(3), 207-223, 201909
  78. ★, Computer-aided diagnosis system for osteoporosis based on quantitative evaluation of mandibular lower border porosity using panoramic radiographs, DENTOMAXILLOFACIAL RADIOLOGY, 49(4), 2020
  79. Surgical Sealing of Laterally Localized Accessory Root Canal with Resin Containing S-PRG Filler in Combination with Non-Surgical Endodontic Treatment: A Case Report., Dent J (Basel), 8(4), 131, 20201120
  80. Do various imaging modalities provide potential early detection and diagnosis of medication-related osteonecrosis of the jaw? A review, DENTOMAXILLOFACIAL RADIOLOGY, 50(6), 2021
  81. Surgical Sealing of Laterally Localized Accessory Root Canal with Resin Containing S-PRG Filler in Combination with Non-Surgical Endodontic Treatment: A Case Report, DENTISTRY JOURNAL, 8(4), 202012
  82. Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning, SCIENTIFIC REPORTS, 12(1), 20220107
  83. Evaluation of alveolar bone hypomineralization in pediatric hypophosphatasia using orthopantomography, SCIENTIFIC REPORTS, 12(1), 20220124

Invited Lecture, Oral Presentation, Poster Presentation

  1. Outcome of remained swallowing disorder due to an odontogenic infection-related neck abscess: a case repor, Nagasaki T Yoshikawa M, Kawagoe M, Yamada S, Yoshida M, Otsuka M, Konishi M, Suei Y, Nakamoto T, Kakimoto N, The first annual autumn meeting of Japanese Society of Oral and Maxillofacial Radiology, 2020/10/30, Without Invitation, Japanese
  2. Central giant cell lesions of the mandibular condyle: 2 case reports, 2019/12/07, Without Invitation, English
  3. T2-relaxation times of the temporomandibular joint using 3.0T MRI, Kakimoto N, Nagasaki T, Akiyama Y, Yamaoka H, Shimabukuro K, Wongratanich P, Verdonschot RG, Konishi M, Otsuka M, NakamotoT, Suei Y, 22nd International Congress of DentoMaxilloFacial Radiology, 2019/08/22, Without Invitation, English, International Congress of DentoMaxilloFacial Radiology, Philadelphia
  4. Quantifying of image evaluation method of computer-aided screening support system for osteoporosis based on detection of linearly eroded endosteal margin of lower border of mandible on panoramic radiographs, Takashi Nakamoto, Seina Hatsuta, Shotaro Yagi, Akira Taguchi, Naoya Kakimoto, The 60th general assembly and annual scientific congress, 2019/06/15, Without Invitation, Japanese, Japanese Society for Oral and Maxillofacial Radiology, Tokyo
  5. New advanced computer-aided diagnosis system to screen osteoporosis using dental panoramic radiographs, Takashi Nakamoto, MD Mahmud Uz Zaman, Akira Taguchi, Keiji Tanimoto, Computer Assisted Radiology and Surgery 28th International Congress and Exhibition, 2014/06/25, Without Invitation, English, Computer Assisted Radiology and Surgery, Fukuoka, Japan, A computer-aided diagnosis system to screen osteoporosis using dental panoramic radiographs was developed in 2008 in the department of oral and maxillofacial radiology, Hiroshima University Hospital [1]. This system can detect the change of inferior border of mandibular cortex, such as erosion, fissuring, on dental panoramic radiographs which was seen in the patients of low bone mineral density (BMD). Although the system had high diagnostic accuracy, selecting operation of region of interests (ROI) was manual. Therefore, the system had some difficulty for perfect reproducibility. Furthermore, since the size of ROI was small (100*100 pixels of domain directly under mental foramen), the part of cortical change might not be contained enough. The purpose of this study is 1: to automate selection of ROI for perfect reproducibility, 2: to expand ROI to detect the changed area as much as possible, and 3: to evaluate the diagnostic performance.

Patented

  1. Patent, JP3964795
  2. Patent, 5935061, 2016/05/20

External Funds

Acceptance Results of Competitive Funds

  1. KAKENHI, Computer aided diagnosis system to screen for osteoporosis based on trabecular pattern of jaw, 2006, 2008

Social Activities

Organizing Academic Conferences, etc.

  1. 2011/05